WO1998007375A1 - Endovascular flexible stapling device - Google Patents

Endovascular flexible stapling device

Info

Publication number
WO1998007375A1
WO1998007375A1 PCT/US1997/014772 US9714772W WO1998007375A1 WO 1998007375 A1 WO1998007375 A1 WO 1998007375A1 US 9714772 W US9714772 W US 9714772W WO 1998007375 A1 WO1998007375 A1 WO 1998007375A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
flexible
device
stapling
shaft
end
Prior art date
Application number
PCT/US1997/014772
Other languages
French (fr)
Inventor
Robert E. Michler
Shunichi Homma
Original Assignee
The Trustees Of Columbia University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/068Surgical staplers, e.g. containing multiple staples or clamps
    • A61B17/0682Surgical staplers, e.g. containing multiple staples or clamps for applying U-shaped staples or clamps, e.g. without a forming anvil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/0218Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • A61B17/0644Surgical staples, i.e. penetrating the tissue penetrating the tissue, deformable to closed position
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/10Surgical instruments, devices or methods, e.g. tourniquets for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2466Delivery devices therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238Type of minimally invasive operation
    • A61B2017/00243Type of minimally invasive operation cardiac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00367Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00668Type of implements the implement being a tack or a staple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00862Material properties elastic or resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421Cannulas
    • A61B17/3423Access ports, e.g. toroid shape introducers for instruments or hands
    • A61B2017/3425Access ports, e.g. toroid shape introducers for instruments or hands for internal organs, e.g. heart ports

Abstract

The present invention concerns a flexible stapling device (1). More particularly, this invention concerns a flexible endovascular stapling device (1) for an intravascular procedure such as patent foramen ovale closure, which is designed to avoid open heart surgery by permitting the closure of the defect utilizing a stapling means (26) which is positioned by using a flexible shaft/guidewire system.

Description

ENDOVASCULAR FLEXIBLE STAPLING DEVICE

FIELD OF THE INVENTION

The present invention relates to a flexible stapling device. More particularly, this invention relates to a flexible endovascular stapling device useful for intravascular procedures such as patent foramen ovale closure, atrial septal defect closure, valve repair, or valve replacement, which is designed to avoid open heart surgery by permitting the closure of the defect and/or valve repair or replacement utilizing a stapling means which is positioned by using a flexible shaft/guide wire system or by direct vision.

BACKGROUND OF THE INVENTION

Cryptogenic strokes potentially account for 40% of the 500,000 strokes which occur in the United States each year. Many of these events may be associated with a patent foramen ovale (small atrial septal defect) which permits debris in the venous circulation to cross over into the arterial circulation where it may travel to the brain. Treatment for these patients often includes open heart surgery to close the defect. A number of prior art references are known:

U.S. Patent No. 4,473,077, which issued to Noiles et al on September 25, 1984, discloses a flexible shafted surgical stapler generally useful for anastomosis procedures;

U.S. Patent No. 4,485,817, which issued to Swiggett on December 4, 1984, teaches a stapler with flexible shaft construction having hydraulic transmission/drive means . This stapler is used primarily for anastomosis of hollow body vessels; and U.S. Patent No. 5,042,707, which issued to Taheri on August 27, 1991, relates to an articulated stapler for use in the vascular system.

However, none of the above references teaches the use of a flexible stapler for intravascular procedures such as patent foramen ovale closure or a flexible stapler suitable for these procedures .

OBJECTS OF THE INVENTION

It is an object of the invention to provide an endovascular flexible stapling device.

It is also an object of the invention to provide an endovascular flexible stapling device useful for closure of a patent foramen ovale defect, atrial or ventricular septal defect closure, valve repair, or valve replacement, without the need for open heart surgery.

It is a further object of the invention to provide a method of performing intravascular procedures whereby a endovascular flexible stapling device is inserted into a body.

It is a yet further object of the invention to provide for a method of closing a patent foramen ovale defect, atrial or ventricular septal defect closure, valve repair, or valve replacement, without the need for open heart surgery.

These and other objects of the invention will become apparent from the following discussion of the invention.

SUMMARY OF THE INVENTION

The present invention provides for a endovascular flexible stapling device. More particularly, this invention provides for a flexible endovascular stapling device for a procedure such as patent foramen ovale closure, which is designed to avoid open heart surgery by permitting the closure of the defect utilizing a stapling means which is positioned by using a flexible shaft/guide wire system introduced via the femoral vein or the jugular vein. One application for the flexible stapling device of the present invention is to pass the device via a femoral vein into the right atrium of the heart and, with the guidance of transesophageal echocardiography, position the device, and then fire one or more staples to obtain closure of the defect. The construction and obvious advantages of the system provided for by the present invention will be more clearly understood from the following description of the various specific embodiments when read in conjunction with the accompanying drawings.

BRIEF DESCRIPTION OF THE DRAWINGS

Fig. 1 is a longitudinal, partly cross-sectional view of the flexible stapling device of the present invention; Fig. 1(a) is an end view of the flexible stapling device of Fig. 1 showing in cross-section the position of the staples prior to use for effecting closure of a defect;

Fig. 1(b) is a lateral view of a typical staple which is incorporated into the distal end of the device of Fig. 1; Fig. 1(c) is a cross-sectional view of the distal end of the device of Fig. 1(a), showing a staple in a closed position;

Fig. 2 is a longitudinal view of the introducer element used for insertion of the flexible stapling device;

Fig. 3 is a longitudinal view of the guidewire upon which the flexible stapling device of the present invention glides to position the device in proximity to the defect to be closed;

Fig. 4 is a longitudinal view of a typical dilator which is used for gradually increasing the size of a vein to permit the easy introduction of the flexible stapling device of the present invention; and

Fig. 5 is a perspective view of a staple useful according to the invention.

DETAILED DESCRIPTION OF THE INVENTION The present invention is directed to an endovascular flexible stapling device. More particularly, this invention relates to a transfemoral flexible stapling device useful for a number of intravascular procedures. For example, the flexible stapling device can be used for patent foramen ovale closure which is designed to avoid open heart surgery by permitting the closure of the defect utilizing a stapling means which is positioned by using a flexible shaft/guide wire system. However, the device can also be used for atrial or ventricular septal defect closure or valve repair or replacement by an endovascular route or by direct vision.

As noted above, many of the cryptogenic strokes which occur in the United States each year can be associated with the existence of the small atrial septal defects known as patent foramen ovale defects. Historically the primary treatment used for patients who may have been diagnosed with such defects has been medical therapy with anticoagulants or anti-platelet agents, or open heart surgery to repair the septal defect.

The device of the present invention is designed to avoid open heart surgery by allowing for the closure of the septal defect utilizing a flexible shaft device which incorporates a stapling means. This device may be introduced by a femoral vein into the right atrium of the patient's heart where, with the guidance of transesophageal echocardiography, the device may be positioned and staples may be fired.

The invention can perhaps be better appreciated by making reference to the drawings. With reference to Fig. 1 a longitudinal, partly cross-sectional view of the flexible stapling device 1 of the present invention is shown, wherein the essential components are depicted. A flexible catheter shaft 10 is shown which incorporates at the proximal end 11 multiple hand grips 12 for maneuvering the device 1 into a patient's vein and properly locating the distal end 14 in proximity to the defect to be closed. Distal to the hand grips 12 is a guidewire port 16, through which passes the proximal end of a guidewire 18 over which the flexible stapling device 1 slides and is guided into position. Guidewire port 16 could optionally be located elsewhere, for example, at the proximal portion 17 of hand grips 12. Distal to guidewire port 16 is a slide mechanism 20 for retracting a retractable external housing 22, located at the distal end 14 of flexible shaft 10. Slide mechanism 20 is operatively connected by suitable actuation means 24 to retractable external housing 22 to facilitate retraction of the housing 22 once the distal end 14 of the device 1 has been properly positioned in proximity to the defect to be closed. Retractable housing 22 could comprise a cylindrical member having an inner diameter slightly greater then the outer diameter of shaft 10.

Located within retractable housing 22 are one or more, preferably 2 or 4, barbed staples 26 which have been properly positioned to present intimate contact between the barbed tips 28 of the staples 26 and the portion of the patient's septum to be closed once external housing 22 has been retracted.

Fig. la is a cross-sectional view of the distal end of the flexible device 1 of Fig. 1 showing four separate barbed staples 26 releasably positioned on a staple holding member 27 within external housing 22. Each of the staples 26 has been preformed and has barbed ends 28 for insertion into the septum wall presenting the defect. Holding member 27 for the staples 26 has a guidewire exit port 30 through which the guidewire 18 extends distally from the flexible shaft 10 of the device.

An actuator such as handgrips 12 or, optionally, an actuator 15, is operatively connected to holding member 27 and/or staple closer 25, so that staples 26 are simultaneously closed and released when the handgrips 12 are squeezed together or actuator 15 is activated. The operative connection can be mechanical, electrical, or other. After discharge of staples 26, holding member 27 could be either re-fitted with new staples 26 or replaced with a replacement holding member 27 with staples already in place, e.g., a "clip".

In Fig. lb a typical barbed staple 26 is depicted showing the angular preformed configuration of the staple 26. The barbed tips 28 allow for the insertion of the staples to effect closure of the defect without allowing them to spontaneously release from the wall in which they have been inserted. Fig. 1(c) represents the distal end of flexible device '1 where external housing 22 has been retracted and staple 26 has been closed. Barbed ends 28 of staple 26 are in a closed, almost touching position. In one embodiment of the invention, staple closer 25 moves distally relative to holding member 27 to cause barbed ends 28 to close on the intended target tissue or organ, such as the septum. Optionally, other mechanisms that can be activated proximally, are operatively connected to a distal staple holding member, and cause the staples to close on an intended target could be used in place of the system described here. Also, it is contemplated that the device 1 could optionally comprise fiber optics and/or light or imaging transmitting means, as well as one or more working channels or lumens . With reference to Fig. 2, a longitudinal view of an introducer element 40 of the system of the present invention is depicted. A one way-valve 42 is located at the proximal end 41 of the introducer element 40 and a generally circular opening 44 is located at the distal end thereof. Fig. 3 depicts a perspective view of the guidewire 50 showing a curved tip 52 at the distal end thereof.

Fig. 4 depicts a perspective view of a typical dilator 60, which can be a set of 2 or more progressively larger dilators for gradual dilation of a vein or artery. The last dilator passes first through introducer 40 and then into, for example, a vein. In a set of three dilators, the lengths could be 20 cm, 20 cm, and 55 cm. An orifice 62 is located at the proximal end of dilator 60 for passage of the guidewire. A tapered tip 64 is located near the distal end thereof, and a generally circular opening 66 is located at the distal end.

It is contemplated that the flexible shaft of the stapling device of the present invention may be effectively constructed of a suitable wire-reinforced polymeric material. Preferably the material chosen should allow for the easy curvature of the shaft of the device without the need for excessive forces being applied, while at the same time providing for the necessary overall rigidity to the shaft to allow for the insertion of the device in the patient's vein.

In overall length the flexible stapling device depicted in Fig. 1 will be approximately 110 cm. Shorter or longer overall lengths are also contemplated as may be required to effect a particular procedure.

The overall diameter of the cross-section of the flexible shaft 10 of the device 1 depicted in Fig. 1 is approximately 5 mm. It is contemplated that similar devices may be constructed having overall diameters of the flexible shaft which vary somewhat to accommodate the different size veins into which the device must be inserted. Therefore, shaft diameters could range from about 5 to about 15 mm.

The retractable external housing 22 at the distal end of the device 1 will have an overall diameter of approximately 5.5 mm to 16 mm. Again, variations in this diameter are contemplated depending upon the needs of a particular procedure and to accommodate patients having unduly small veins.

The barbed staples which are located at the distal end of the stapler device will have an overall length of approximately 4 mm to 14 mm. Again, the precise configuration of the staple, the actual dimensions of the barbs as well as the overall size of the staple itself, are variables which will be determined by the conditions which prevail in carrying out any particular procedure and the physiological requirements of the patient involved .

The number and actual location of staples within the retractable external housing 22 may also vary depending upon the needs of a particular procedure. In an optional embodiment of the invention shown in Fig. 5, each staple 70 may have a filament 72 extending from staple 70 a sufficient length that the proximal end of each filament would extend outside the patient's body. Then, if staple 70 were not positioned properly, the surgeon could retrieve staple 70 by pulling firmly on filament 72. If staple 70 is properly PC17US97/14772 positioned, filament 72 would merely be cut. It is contemplated that a length of from about 20 to 100 cm of filament 72 would be fixedly attached to each staple 70. The filaments 72 could be comprised of any flexible, physiologically acceptable natural or manufactured material, such as acetates or poly- acetates, etc., used in sutures. The distal end of each filament 72 would be glued or physically affixed to each staple 70.

With regard to the introducer element depicted in Fig. 2 it is generally contemplated that the overall length of this element, taken from the base of the one-way valve located at the proximal end thereof to the distal tip of the element, will be from about 30 to 60 cm, preferably approximately 50 cm. The overall diameter of the introducer element at the distal end will be from about 6 mm to 20 mm, or as initially depicted approximately 6.7 mm, to accommodate the passage of the flexible shaft stapling device through the opening provided.

The guidewire which is depicted in Fig. 3 will have an overall length of at least from about 90 to 130 cm, preferably 110 cm, to properly function with the flexible shaft stapling device depicted in Fig.l. The overall diameter of the guidewire will generally be from about 0.30 to 0.50 mm, preferably about 0.38 mm, although variations in the actual diameter of the guidewire are contemplated. The dilator depicted in Fig. is typical of a series of three or more dilators which vary in length from about 20 to 55 cm.

The overall diameter of the largest cross-section of each dilator will be no more than the opening provided at the distal end of the introducer element. It is, therefore, contemplated that the overall diameter of the dilators will be from about 5 to 15 mm.

In the method of the invention one or more of the smaller diameter dilators is inserted into a femoral vein to permit gradual enlargement of the patient's vein using successively larger diameter dilators and ultimately to allow entry of the introducer element. The largest in the series of dilators used will be inserted first through the introducer element and then into the vein which had been previously enlarged using smaller diameter dilators. After the introducer element has been properly positioned within the patient's vein, and the guidewire positioned through the defect, a flexible stapling device according to the invention is then inserted through the introducer over the guidewire and with the aid of trans-esophageal echocardiography or other similar procedure, the distal end of the flexible stapler device is positioned adjacent or near to the patent foramen ovale requiring closure. The staples are then propelled or fired by retracting the external housing utilizing the slide mechanism provided in the proximal end of the flexible stapler shaft.

While, as described above, the flexible stapling device of the invention is useful for patent foramen ovale closure, there are other intravascular procedures for which the flexible stapling device can be used. Such procedures include, for example, the correction of atrial septal or ventricle septal defect, closure of paravalvular leaks, or annuloplasty repair of valvular insufficiency or valve replacement.

Also, the flexible stapling device need not be inserted percutaneously. In certain applications a cut down procedure at the leg can be employed with direct vision of the procedure or with the heart open during minimally invasive surgery. In addition, multiple sizes of the flexible stapling device should be available .

It will be further apparent to one skilled in this art that the improvements provided for in the present invention, while described with relation to certain specific physical embodiments also lend themselves to being applied in other physical arrangements not specifically provided for herein, which are nonetheless within the spirit and scope of the invention taught here.

Claims

We Claim :
1. A flexible shaft stapling device comprising a generally elongated flexible shaft having proximal and distal ends, an actuator located at the proximal end of said flexible shaft , a guidewire entry port located at the proximal end of said flexible shaft, a guidewire exit port located at the distal end of said flexible shaft, one or more staples releasably positioned on a holding member at the distal end of said flexible shaft, and a stapler closer operatively connected to the actuator for closing the staples, wherein activation of the actuator causes the one or more staples to close and separate from the holding member.
2. The flexible shaft stapling device of Claim 1, wherein the flexible shaft is constructed of a suitable wire reinforced plastic material.
3. The flexible shaft stapling device of Claim 1, wherein the staples located within the retractable housing at the distal end are barbed.
4. The flexible shaft stapling device of Claim 1, wherein the staples are preformed to effect ease of closure upon contact with the wall of a patient's heart or blood vessel .
5. The flexible shaft stapling device of Claim 1, wherein 2 or 4 individual staples are positioned on the holding member .
6. The flexible shaft stapling device of Claim 1, wherein the overall length of the flexible stapling device is from about 80 to 150 cm.
7. The flexible shaft stapling device of Claim 6, wherein the overall length of the flexible stapling device is approximately 110 cm.
8. The flexible shaft stapling device of Claim 1, wherein the overall diameter of the cross-section of the flexible shaft is from about 5 to about 15 mm.
9. The flexible shaft stapling device of Claim 8, wherein the overall diameter of the cross-section of the flexible shaft is approximately 5 mm.
10. The flexible shaft stapling device of Claim 1, wherein the staples have an overall length of approximately 4 mm to 14 mm.
11. A flexible shaft stapling device of Claim 1, wherein the staples are preformed.
12. A flexible shaft stapling device of Claim 1, wherein the staples can be released simultaneously.
13. The flexible shaft stapling device of Claim 1, wherein the actuator is operatively connected to the holding member so that the staples can be simultaneously released from the holding member when the actuator is actuated.
14. The flexible shaft stapling device of Claim 1, wherein a retractable housing is positioned at the distal end of the flexible shaft and the retractable housing is operatively connected to an actuator at the proximal end of the flexible shaft.
15. The flexible shaft stapling device of Claim 14, wherein the retractable housing has an overall diameter of approximately 5.5 mm to 16 mm.
16. A flexible shaft stapling device comprising a generally elongated flexible shaft having proximal and distal ends, an actuator located at the proximal end of said flexible shaft, one or more staples releasably positioned on a holding member at the distal end of said flexible shaft, and a stapler closer operatively connected to the actuator for closing the staples, wherein activation of the actuator causes the one or more staples to close and separate from the holding member.
17. A system for endovascular closure comprising: a generally elongated introducer element having at the proximal end thereof a one way valve and having at the distal end thereof a generally circular opening; an elongated guidewire having a curved tip at the" distal end thereof; one or more longitudinally-extending dilators of varying diameters each having at the proximal end thereof an orifice and each having at the distal end thereof a tapered tip culminating in a generally circular opening for guidewire passage; and an elongated flexible shaft stapling device according to Claim 1.
18. The system according to Claim 17, wherein the generally elongated introducer element has a length of approximately 50 cm.
19. The system according to Claim 17, wherein the generally elongated introducer element has an overall diameter of from about 6 to 20 mm.
20. The system according to Claim 17, wherein the guide wire has an overall diameter of approximately 0.38 mm.
21. The system according to Claim 17, wherein each dilator has an overall length of from about 20 cm to about 55 cm.
22. The system according to Claim 17, wherein the overall diameter of the largest cross-section of each dilator is from about 5 to about 15 mm.
23. The system according to Claim 17 for effecting closure of a patent foramen ovale defect, atrial or ventricular septal defect closure, valve repair, or valve replacement, without the need for open heart surgery.
24. The system according to Claim 17 that is useful during minimally invasive open heart surgery and under direct vision.
25. A method of effecting intravascular closure comprising:
(a) advancing a guidewire percutaneously or by incision using Seldinger technique into a patient's vein; (b) advancing one or more dilators successively over a guidewire into the proximal end of the femoral vein and distally into the patient's femoral vein to permit gradual enlargement ;
(c) advancing the introducer over the guidewire where the introducer has distal and proximal ends and the proximal end of the introducer remains outside the patient ' s body;
(d) advancing a guidewire through the introducer and distally to a position through the defect in the patient's heart septum or other appropriate location;
(e) advancing a flexible stapling device having distal and proximal ends, where said distal end comprises staples and a retractable external housing and the proximal end comprises actuating means to retract the housing and to cause the staples to be fired;
(f) positioning the distal end of the flexible shaft stapling device in proximity to the defect; and
(g) activating the mechanism to effect the positioning of the staples located at the distal end of the flexible shaft; and
(h) withdrawing the flexible stapling device and then the introducer from the patient's vein.
26. The method of Claim 25, wherein transesophageal echocardiography is used to position the guidewire distal tip and/or the distal tip of the stapler device.
27. The method of Claim 25, wherein a patent foramen ovale is closed.
28. The method of Claim 25, wherein a atrial septal defect or a ventricle septal defect is closed or treated.
29. The method of Claim 25, wherein a paravalvular leak is closed.
30. The method of Claim 25, wherein valvular insufficiency is repaired, or valvular stenoses are repaired or replaced with prosthetic material/devices.
31. In a staple useful for surgical application in a body, the improvement wherein the distal portion of a filament having proximal and distal portions is fixedly attached to the staple .
PCT/US1997/014772 1996-08-22 1997-08-22 Endovascular flexible stapling device WO1998007375A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US2464096 true 1996-08-22 1996-08-22
US60/024,640 1996-08-22

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US09242969 US6482224B1 (en) 1996-08-22 1997-08-22 Endovascular flexible stapling device
US10104876 US7794474B2 (en) 1996-08-22 2002-03-21 Endovascular flexible stapling device
US12140605 US8167905B2 (en) 1996-08-22 2008-06-17 Endovascular flexible stapling device
US12144828 US8048110B2 (en) 1996-08-22 2008-06-24 Endovascular flexible stapling device
US13228801 US9468437B2 (en) 1996-08-22 2011-09-09 Endovascular flexible stapling device
US13435582 US20120193391A1 (en) 1996-08-22 2012-03-30 Endovascular flexible stapling device
US14727424 US20150265274A1 (en) 1996-08-22 2015-06-01 Endovascular Flexible Stapling Device
US14731130 US9610078B2 (en) 1996-08-22 2015-06-04 Endovascular flexible stapling device
US15447051 US20170172569A1 (en) 1996-08-22 2017-03-01 Endovascular flexible stapling device

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US09242969 A-371-Of-International 1997-08-22
US09242969 A-371-Of-International US6482224B1 (en) 1996-08-22 1997-08-22 Endovascular flexible stapling device
US10104876 Continuation US7794474B2 (en) 1996-08-22 2002-03-21 Endovascular flexible stapling device

Publications (1)

Publication Number Publication Date
WO1998007375A1 true true WO1998007375A1 (en) 1998-02-26

Family

ID=21821636

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1997/014772 WO1998007375A1 (en) 1996-08-22 1997-08-22 Endovascular flexible stapling device

Country Status (2)

Country Link
US (9) US6482224B1 (en)
WO (1) WO1998007375A1 (en)

Cited By (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003759A3 (en) * 1998-07-15 2000-04-20 St Jude Medical Mitral and tricuspid valve repair
US6461366B1 (en) 1997-09-12 2002-10-08 Evalve, Inc. Surgical device for connecting soft tissue
US6629534B1 (en) 1999-04-09 2003-10-07 Evalve, Inc. Methods and apparatus for cardiac valve repair
US6743239B1 (en) 2000-05-25 2004-06-01 St. Jude Medical, Inc. Devices with a bendable tip for medical procedures
US6752813B2 (en) 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
WO2004087235A2 (en) 2003-03-27 2004-10-14 Cierra, Inc. Methods and apparatus for treatment of patent foramen ovale
US6986775B2 (en) 2002-06-13 2006-01-17 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US7048754B2 (en) 2002-03-01 2006-05-23 Evalve, Inc. Suture fasteners and methods of use
US7373207B2 (en) 2001-12-08 2008-05-13 Lattouf Omar M Treatments for a patient with congestive heart failure
US7509959B2 (en) 1997-06-27 2009-03-31 The Trustees Of Columbia University In The City Of New York Method and apparatus for circulatory valve repair
US7678132B2 (en) 2001-09-06 2010-03-16 Ovalis, Inc. Systems and methods for treating septal defects
US7682319B2 (en) 1999-04-09 2010-03-23 Evalve, Inc. Steerable access sheath and methods of use
US7740640B2 (en) 2001-09-06 2010-06-22 Ovalis, Inc. Clip apparatus for closing septal defects and methods of use
US7811296B2 (en) 1999-04-09 2010-10-12 Evalve, Inc. Fixation devices for variation in engagement of tissue
US7842069B2 (en) 2004-05-07 2010-11-30 Nmt Medical, Inc. Inflatable occluder
US7846179B2 (en) 2005-09-01 2010-12-07 Ovalis, Inc. Suture-based systems and methods for treating septal defects
US7914527B2 (en) 2003-03-27 2011-03-29 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US7922716B2 (en) 2003-03-27 2011-04-12 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of anatomic tissue defects
US7967840B2 (en) 2001-12-19 2011-06-28 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
US7972330B2 (en) 2003-03-27 2011-07-05 Terumo Kabushiki Kaisha Methods and apparatus for closing a layered tissue defect
US8021362B2 (en) 2003-03-27 2011-09-20 Terumo Kabushiki Kaisha Methods and apparatus for closing a layered tissue defect
US8052678B2 (en) 2003-03-27 2011-11-08 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US8057469B2 (en) 2003-03-27 2011-11-15 Terumo Kabushiki Kaisha Methods and apparatus for treatment of patent foramen ovale
US8070826B2 (en) 2001-09-07 2011-12-06 Ovalis, Inc. Needle apparatus for closing septal defects and methods for using such apparatus
US8109274B2 (en) 2005-04-11 2012-02-07 Terumo Kabushiki Kaisha Methods and electrode apparatus to achieve a closure of a layered tissue defect
US8114123B2 (en) 2003-09-19 2012-02-14 St. Jude Medical, Inc. Apparatus and methods for tissue gathering and securing
US8133221B2 (en) 2004-06-21 2012-03-13 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of anatomic tissue defects
US8157829B2 (en) 2003-11-06 2012-04-17 Pressure Products Medical Supplies, Inc. Transseptal puncture apparatus
US8292910B2 (en) 2003-11-06 2012-10-23 Pressure Products Medical Supplies, Inc. Transseptal puncture apparatus
US8568447B2 (en) 2004-05-06 2013-10-29 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US8568431B2 (en) 2004-03-03 2013-10-29 W.L. Gore & Associates, Inc. Delivery/recovery system for septal occluder
US8579936B2 (en) 2005-07-05 2013-11-12 ProMed, Inc. Centering of delivery devices with respect to a septal defect
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
US8920434B2 (en) 2005-03-02 2014-12-30 St. Jude Medical, Cardiology Division, Inc. Remote body tissue engaging methods and apparatus
US9005242B2 (en) 2007-04-05 2015-04-14 W.L. Gore & Associates, Inc. Septal closure device with centering mechanism
US9017373B2 (en) 2002-12-09 2015-04-28 W.L. Gore & Associates, Inc. Septal closure devices
US9028527B2 (en) 2002-06-05 2015-05-12 W.L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with radial and circumferential support
US9060858B2 (en) 2009-09-15 2015-06-23 Evalve, Inc. Methods, systems and devices for cardiac valve repair
US9072513B2 (en) 2002-06-13 2015-07-07 Guided Delivery Systems Inc. Methods and devices for termination
US9084603B2 (en) 2005-12-22 2015-07-21 W.L. Gore & Associates, Inc. Catch members for occluder devices
US9138562B2 (en) 2007-04-18 2015-09-22 W.L. Gore & Associates, Inc. Flexible catheter system
US9149263B2 (en) 2003-07-14 2015-10-06 W. L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9216014B2 (en) 2002-06-03 2015-12-22 W.L. Gore & Associates, Inc. Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
US9226825B2 (en) 2002-06-13 2016-01-05 Guided Delivery Systems, Inc. Delivery devices and methods for heart valve repair
US9241695B2 (en) 2002-03-25 2016-01-26 W.L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure clips
US9326759B2 (en) 2003-07-14 2016-05-03 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9468528B2 (en) 2002-06-13 2016-10-18 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US9468437B2 (en) 1996-08-22 2016-10-18 The Trustees Of Columbia University In The City Of New York Endovascular flexible stapling device
US9474517B2 (en) 2008-03-07 2016-10-25 W. L. Gore & Associates, Inc. Heart occlusion devices
US9510829B2 (en) 1999-04-09 2016-12-06 Evalve, Inc. Fixation devices, systems and methods for engaging tissue
US9545247B2 (en) 2004-05-07 2017-01-17 W.L. Gore & Associates, Inc. Catching mechanisms for tubular septal occluder
US9616197B2 (en) 2009-01-20 2017-04-11 Ancora Heart, Inc. Anchor deployment devices and related methods
US9636106B2 (en) 2008-10-10 2017-05-02 Ancora Heart, Inc. Termination devices and related methods
US9706996B2 (en) 2008-02-06 2017-07-18 Ancora Heart, Inc. Multi-window guide tunnel
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
US9861350B2 (en) 2010-09-03 2018-01-09 Ancora Heart, Inc. Devices and methods for anchoring tissue
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
US9999442B2 (en) 2001-12-08 2018-06-19 Trans Cardiac Therapeutics, Inc. Methods for accessing a left ventricle

Families Citing this family (187)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766183A (en) 1996-10-21 1998-06-16 Lasersurge, Inc. Vascular hole closure
US9320503B2 (en) 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Devices, system, and methods for guiding an operative tool into an interior body region
US7491232B2 (en) 1998-09-18 2009-02-17 Aptus Endosystems, Inc. Catheter-based fastener implantation apparatus and methods with implantation force resolution
US7235087B2 (en) 1999-03-04 2007-06-26 Abbott Park Articulating suturing device and method
US6964668B2 (en) 1999-03-04 2005-11-15 Abbott Laboratories Articulating suturing device and method
US7001400B1 (en) 1999-03-04 2006-02-21 Abbott Laboratories Articulating suturing device and method
US20040092964A1 (en) 1999-03-04 2004-05-13 Modesitt D. Bruce Articulating suturing device and method
US8216256B2 (en) 1999-04-09 2012-07-10 Evalve, Inc. Detachment mechanism for implantable fixation devices
EP1210014A1 (en) * 1999-09-07 2002-06-05 Microvena Corporation Retrievable septal defect closure device
US6391048B1 (en) 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US7842068B2 (en) 2000-12-07 2010-11-30 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US6461364B1 (en) 2000-01-05 2002-10-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US6913608B2 (en) * 2000-10-23 2005-07-05 Viacor, Inc. Automated annular plication for mitral valve repair
DE60132005D1 (en) * 2000-06-23 2008-01-31 Viacor Inc Automatic circular convolution for Mitral Valve Repair
DE60143324D1 (en) 2000-09-08 2010-12-02 Abbott Vascular Inc An apparatus for locating a punctured blood vessel
US6626918B1 (en) 2000-10-06 2003-09-30 Medical Technology Group Apparatus and methods for positioning a vascular sheath
US20060020336A1 (en) * 2001-10-23 2006-01-26 Liddicoat John R Automated annular plication for mitral valve repair
US7211101B2 (en) 2000-12-07 2007-05-01 Abbott Vascular Devices Methods for manufacturing a clip and clip
US6623510B2 (en) 2000-12-07 2003-09-23 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7806904B2 (en) 2000-12-07 2010-10-05 Integrated Vascular Systems, Inc. Closure device
US8083768B2 (en) 2000-12-14 2011-12-27 Ensure Medical, Inc. Vascular plug having composite construction
US6896692B2 (en) 2000-12-14 2005-05-24 Ensure Medical, Inc. Plug with collet and apparatus and method for delivering such plugs
US6846319B2 (en) 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
US6890343B2 (en) 2000-12-14 2005-05-10 Ensure Medical, Inc. Plug with detachable guidewire element and methods for use
US6623509B2 (en) 2000-12-14 2003-09-23 Core Medical, Inc. Apparatus and methods for sealing vascular punctures
US7186264B2 (en) * 2001-03-29 2007-03-06 Viacor, Inc. Method and apparatus for improving mitral valve function
WO2002098302A1 (en) 2001-06-07 2002-12-12 Christy Cummins Surgical staple
WO2003022344A3 (en) 2001-09-06 2003-07-31 Nmt Medical Inc Flexible delivery system
US20030078601A1 (en) * 2001-10-22 2003-04-24 Oleg Shikhman Crimping and cutting device
JP4351531B2 (en) * 2001-10-22 2009-10-28 インターヴェンショナル セラピーズ エルエルシー Wound suturing device
US6575971B2 (en) 2001-11-15 2003-06-10 Quantum Cor, Inc. Cardiac valve leaflet stapler device and methods thereof
US8231639B2 (en) 2001-11-28 2012-07-31 Aptus Endosystems, Inc. Systems and methods for attaching a prosthesis within a body lumen or hollow organ
CN101466316B (en) 2005-10-20 2012-06-27 阿普特斯内系统公司 Devices systems and methods for prosthesis delivery and implantation including the use of a fastener tool
US8075570B2 (en) * 2001-11-28 2011-12-13 Aptus Endosystems, Inc. Intraluminal prosthesis attachment systems and methods
US20050177180A1 (en) 2001-11-28 2005-08-11 Aptus Endosystems, Inc. Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ
CA2464048C (en) * 2001-11-28 2010-06-15 Lee Bolduc Endovascular aneurysm repair system
EP1467661A4 (en) 2001-12-19 2008-11-05 Nmt Medical Inc Septal occluder and associated methods
US6749621B2 (en) 2002-02-21 2004-06-15 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
CA2488688A1 (en) 2002-06-04 2003-12-11 Christy Cummins Blood vessel closure clip and delivery device
US20040127855A1 (en) * 2002-10-10 2004-07-01 Nmt Medical, Inc. Hemostasis valve
US7087064B1 (en) 2002-10-15 2006-08-08 Advanced Cardiovascular Systems, Inc. Apparatuses and methods for heart valve repair
US7766820B2 (en) 2002-10-25 2010-08-03 Nmt Medical, Inc. Expandable sheath tubing
US7335213B1 (en) 2002-11-15 2008-02-26 Abbott Cardiovascular Systems Inc. Apparatus and methods for heart valve repair
US8187324B2 (en) 2002-11-15 2012-05-29 Advanced Cardiovascular Systems, Inc. Telescoping apparatus for delivering and adjusting a medical device in a vessel
US6945978B1 (en) 2002-11-15 2005-09-20 Advanced Cardiovascular Systems, Inc. Heart valve catheter
US7404824B1 (en) 2002-11-15 2008-07-29 Advanced Cardiovascular Systems, Inc. Valve aptation assist device
US7485143B2 (en) 2002-11-15 2009-02-03 Abbott Cardiovascular Systems Inc. Apparatuses and methods for heart valve repair
US7160309B2 (en) 2002-12-31 2007-01-09 Laveille Kao Voss Systems for anchoring a medical device in a body lumen
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7905900B2 (en) * 2003-01-30 2011-03-15 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7857828B2 (en) 2003-01-30 2010-12-28 Integrated Vascular Systems, Inc. Clip applier and methods of use
EP1596723A2 (en) 2003-02-04 2005-11-23 ev3 Sunnyvale, Inc. Patent foramen ovale closure system
US20040176788A1 (en) * 2003-03-07 2004-09-09 Nmt Medical, Inc. Vacuum attachment system
US7658747B2 (en) 2003-03-12 2010-02-09 Nmt Medical, Inc. Medical device for manipulation of a medical implant
US7473266B2 (en) * 2003-03-14 2009-01-06 Nmt Medical, Inc. Collet-based delivery system
US8714429B2 (en) 2003-04-29 2014-05-06 Covidien Lp Dissecting tip for surgical stapler
EP1648340B1 (en) 2003-05-19 2010-03-03 SeptRx, Inc. Tissue distention device and related methods for therapeutic intervention
CA2533556A1 (en) * 2003-07-23 2005-02-03 Viacor, Inc. Method and apparatus for improving mitral valve function
CA2536368A1 (en) 2003-08-19 2005-03-03 Nmt Medical, Inc. Expandable sheath tubing
CA2538707A1 (en) 2003-09-11 2005-04-21 Nmt Medical, Inc. Suture sever tube
US8137364B2 (en) 2003-09-11 2012-03-20 Abbott Laboratories Articulating suturing device and method
JP2007504885A (en) 2003-09-11 2007-03-08 エヌエムティー メディカル, インコーポレイティッド Device for suturing tissue, system and method
US7462188B2 (en) 2003-09-26 2008-12-09 Abbott Laboratories Device and method for suturing intracardiac defects
US7998112B2 (en) 2003-09-30 2011-08-16 Abbott Cardiovascular Systems Inc. Deflectable catheter assembly and method of making same
EP1680028B1 (en) 2003-10-17 2012-01-25 Tyco Healthcare Group LP Surgical stapling device
US8852229B2 (en) 2003-10-17 2014-10-07 Cordis Corporation Locator and closure device and method of use
US7361183B2 (en) 2003-10-17 2008-04-22 Ensure Medical, Inc. Locator and delivery device and method of use
US20050273119A1 (en) 2003-12-09 2005-12-08 Nmt Medical, Inc. Double spiral patent foramen ovale closure clamp
US7449024B2 (en) 2003-12-23 2008-11-11 Abbott Laboratories Suturing device with split arm and method of suturing tissue
JP2007519498A (en) 2004-01-30 2007-07-19 エヌエムティー メディカル, インコーポレイティッド Device for closing cardiac openings, systems, and methods
US20050192626A1 (en) 2004-01-30 2005-09-01 Nmt Medical, Inc. Devices, systems, and methods for closure of cardiac openings
US20050187568A1 (en) 2004-02-20 2005-08-25 Klenk Alan R. Devices and methods for closing a patent foramen ovale with a coil-shaped closure device
US8025199B2 (en) * 2004-02-23 2011-09-27 Tyco Healthcare Group Lp Surgical cutting and stapling device
US20050267524A1 (en) 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
US8361110B2 (en) 2004-04-26 2013-01-29 W.L. Gore & Associates, Inc. Heart-shaped PFO closure device
US7842053B2 (en) 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
US7704268B2 (en) 2004-05-07 2010-04-27 Nmt Medical, Inc. Closure device with hinges
EP1750592B1 (en) 2004-05-14 2016-12-28 Evalve, Inc. Locking mechanisms for fixation devices
US20050267495A1 (en) * 2004-05-17 2005-12-01 Gateway Medical, Inc. Systems and methods for closing internal tissue defects
US8590760B2 (en) 2004-05-25 2013-11-26 Abbott Vascular Inc. Surgical stapler
CN101056596B (en) 2004-09-14 2011-08-03 爱德华兹生命科学股份公司 Device and method for treatment of heart valve regurgitation
CA2581677C (en) 2004-09-24 2014-07-29 Nmt Medical, Inc. Occluder device double securement system for delivery/recovery of such occluder device
US8052592B2 (en) 2005-09-27 2011-11-08 Evalve, Inc. Methods and devices for tissue grasping and assessment
WO2006048905A1 (en) * 2004-11-05 2006-05-11 Ethicon Endo-Surgery, Inc. A device and method for the therapy of obesity
EP1811905B1 (en) * 2004-11-05 2015-08-12 Ethicon Endo-Surgery, Inc. A device for the therapy of obesity
US7981152B1 (en) 2004-12-10 2011-07-19 Advanced Cardiovascular Systems, Inc. Vascular delivery system for accessing and delivering devices into coronary sinus and other vascular sites
US7462185B1 (en) * 2004-12-23 2008-12-09 Cardican Inc. Intravascular stapling tool
US7678121B1 (en) 2004-12-23 2010-03-16 Cardica, Inc. Surgical stapling tool
US7803142B2 (en) 2005-02-02 2010-09-28 Summit Access Llc Microtaper needle and method of use
WO2011034628A1 (en) 2005-02-07 2011-03-24 Evalve, Inc. Methods, systems and devices for cardiac valve repair
US8277480B2 (en) 2005-03-18 2012-10-02 W.L. Gore & Associates, Inc. Catch member for PFO occluder
US7344544B2 (en) * 2005-03-28 2008-03-18 Cardica, Inc. Vascular closure system
US9149602B2 (en) 2005-04-22 2015-10-06 Advanced Cardiovascular Systems, Inc. Dual needle delivery system
US8088144B2 (en) 2005-05-04 2012-01-03 Ensure Medical, Inc. Locator and closure device and method of use
US8926654B2 (en) 2005-05-04 2015-01-06 Cordis Corporation Locator and closure device and method of use
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US8313497B2 (en) 2005-07-01 2012-11-20 Abbott Laboratories Clip applier and methods of use
US8083754B2 (en) 2005-08-08 2011-12-27 Abbott Laboratories Vascular suturing device with needle capture
US7883517B2 (en) 2005-08-08 2011-02-08 Abbott Laboratories Vascular suturing device
US8267947B2 (en) 2005-08-08 2012-09-18 Abbott Laboratories Vascular suturing device
US8062309B2 (en) * 2005-08-19 2011-11-22 Boston Scientific Scimed, Inc. Defect occlusion apparatus, system, and method
US7766906B2 (en) 2005-08-19 2010-08-03 Boston Scientific Scimed, Inc. Occlusion apparatus
US7824397B2 (en) 2005-08-19 2010-11-02 Boston Scientific Scimed, Inc. Occlusion apparatus
US7837619B2 (en) * 2005-08-19 2010-11-23 Boston Scientific Scimed, Inc. Transeptal apparatus, system, and method
US7998095B2 (en) * 2005-08-19 2011-08-16 Boston Scientific Scimed, Inc. Occlusion device
US20070060895A1 (en) 2005-08-24 2007-03-15 Sibbitt Wilmer L Jr Vascular closure methods and apparatuses
US8920442B2 (en) 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US8758397B2 (en) 2005-08-24 2014-06-24 Abbott Vascular Inc. Vascular closure methods and apparatuses
US9456811B2 (en) 2005-08-24 2016-10-04 Abbott Vascular Inc. Vascular closure methods and apparatuses
US8551135B2 (en) 2006-03-31 2013-10-08 W.L. Gore & Associates, Inc. Screw catch mechanism for PFO occluder and method of use
CA2647505C (en) 2006-03-31 2014-07-29 Nmt Medical, Inc. Deformable flap catch mechanism for occluder device
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US9511214B2 (en) 2006-05-02 2016-12-06 Vascular Access Technologies, Inc. Methods of transvascular retrograde access placement and devices for facilitating therein
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US7842048B2 (en) 2006-08-18 2010-11-30 Abbott Laboratories Articulating suture device and method
US8136711B2 (en) * 2006-09-08 2012-03-20 Tyco Healthcare Group Lp Dissection tip and introducer for surgical instrument
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8403196B2 (en) 2006-09-08 2013-03-26 Covidien Lp Dissection tip and introducer for surgical instrument
US7875053B2 (en) * 2006-09-15 2011-01-25 Cardica, Inc. Apparatus and method for closure of patent foramen ovale
US20080221614A1 (en) * 2007-03-09 2008-09-11 Medtronic Vascular, Inc. Method for Closing an Arteriotomy
US20080249545A1 (en) * 2007-04-06 2008-10-09 Interventional Therapies Suturing, crimping and cutting device
US8226681B2 (en) 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8574244B2 (en) 2007-06-25 2013-11-05 Abbott Laboratories System for closing a puncture in a vessel wall
US20090093826A1 (en) * 2007-10-05 2009-04-09 Cardica, Inc. Patent Foramen Ovale Closure System
US20090105815A1 (en) * 2007-10-19 2009-04-23 Matthew Krever Push-in retainer system for use in the direct plication annuloplasty treatment of mitral valve regurgitation
US8197464B2 (en) * 2007-10-19 2012-06-12 Cordis Corporation Deflecting guide catheter for use in a minimally invasive medical procedure for the treatment of mitral valve regurgitation
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US20090157101A1 (en) 2007-12-17 2009-06-18 Abbott Laboratories Tissue closure system and methods of use
US7841502B2 (en) 2007-12-18 2010-11-30 Abbott Laboratories Modular clip applier
EP2257227A4 (en) * 2008-03-14 2014-03-26 Safestitch Medical Inc Hernia stapler with integrated mesh manipulator
US8870049B2 (en) 2008-03-14 2014-10-28 Transenterix, Inc. Hernia stapler
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US20100098519A1 (en) * 2008-10-17 2010-04-22 Memc Electronic Materials, Inc. Support for a semiconductor wafer in a high temperature environment
US8398676B2 (en) 2008-10-30 2013-03-19 Abbott Vascular Inc. Closure device
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US8323312B2 (en) 2008-12-22 2012-12-04 Abbott Laboratories Closure device
US9179910B2 (en) 2009-03-20 2015-11-10 Rotation Medical, Inc. Medical device delivery system and method
US20100191332A1 (en) 2009-01-08 2010-07-29 Euteneuer Charles L Implantable Tendon Protection Systems and Related Kits and Methods
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US20100179589A1 (en) 2009-01-09 2010-07-15 Abbott Vascular Inc. Rapidly eroding anchor
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US20100185234A1 (en) 2009-01-16 2010-07-22 Abbott Vascular Inc. Closure devices, systems, and methods
US20100204717A1 (en) * 2009-02-12 2010-08-12 Cardica, Inc. Surgical Device for Multiple Clip Application
US8905937B2 (en) 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
US7875029B1 (en) 2009-05-04 2011-01-25 Cardica, Inc. Surgical device switchable between clip application and coagulation modes
WO2010141906A1 (en) * 2009-06-04 2010-12-09 Rotation Medical, Inc. Methods and apparatus for deploying sheet-like materials
US8763878B2 (en) 2009-06-04 2014-07-01 Rotation Medical, Inc. Methods and apparatus having bowstring-like staple delivery to a target tissue
US20100324597A1 (en) * 2009-06-19 2010-12-23 Oleg Shikhman Crimping and cutting device
US8409236B2 (en) 2009-08-21 2013-04-02 Vascular Access Technologies, Inc. Methods of transvascular retrograde access placement and devices for facilitating the placement
US20110054492A1 (en) 2009-08-26 2011-03-03 Abbott Laboratories Medical device for repairing a fistula
US8211121B1 (en) * 2010-03-06 2012-07-03 Q-Tech Medical Incorporated Methods and apparatus for image-guided extraluminal occlusion using clamping jaws
US9198750B2 (en) 2010-03-11 2015-12-01 Rotation Medical, Inc. Tendon repair implant and method of arthroscopic implantation
US8303624B2 (en) 2010-03-15 2012-11-06 Abbott Cardiovascular Systems, Inc. Bioabsorbable plug
US8419767B2 (en) 2010-05-04 2013-04-16 Mustafa H. Al-Qbandi Steerable atrial septal occluder implantation device with flexible neck
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
US8663252B2 (en) 2010-09-01 2014-03-04 Abbott Cardiovascular Systems, Inc. Suturing devices and methods
US9370353B2 (en) 2010-09-01 2016-06-21 Abbott Cardiovascular Systems, Inc. Suturing devices and methods
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
WO2012112565A3 (en) 2011-02-15 2013-01-17 Rotation Medical, Inc. Methods and apparatus for delivering and positioning sheet-like materials
WO2012145059A1 (en) 2011-02-15 2012-10-26 Rotation Medical, Inc. Methods and apparatus for fixing sheet-like materials to a target tissue
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US9414822B2 (en) 2011-05-19 2016-08-16 Abbott Cardiovascular Systems, Inc. Tissue eversion apparatus and tissue closure device and methods for use thereof
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
WO2013119321A1 (en) 2011-12-19 2013-08-15 Rotation Medical, Inc. Fasteners for affixing sheet -like materials to bone or tissue
US9271726B2 (en) 2011-12-19 2016-03-01 Rotation Medical, Inc. Fasteners and fastener delivery devices for affixing sheet-like materials to bone or tissue
US9107661B2 (en) 2011-12-19 2015-08-18 Rotation Medical, Inc. Fasteners and fastener delivery devices for affixing sheet-like materials to bone or tissue
EP2793715B1 (en) 2011-12-19 2018-06-06 Rotation Medical, Inc. Apparatus for forming pilot holes in bone and delivering fasteners therein for retaining an implant
WO2013101638A1 (en) 2011-12-29 2013-07-04 Rotation Medical, Inc. Methods and apparatus for delivering and positioning sheet -like materials in surgery
WO2013101640A1 (en) 2011-12-29 2013-07-04 Rotation Medical, Inc. Guidewire having a distal fixation member for delivering and positioning sheet-like materials in surgery
WO2013101641A3 (en) 2011-12-29 2013-08-22 Rotation Medical, Inc. Anatomical location markers and methods of use in positioning sheet-like materials during surgery
US8858573B2 (en) 2012-04-10 2014-10-14 Abbott Cardiovascular Systems, Inc. Apparatus and method for suturing body lumens
US8864778B2 (en) 2012-04-10 2014-10-21 Abbott Cardiovascular Systems, Inc. Apparatus and method for suturing body lumens
US9623217B2 (en) 2012-05-30 2017-04-18 Vascular Access Techonlogies, Inc. Transvascular access methods
WO2013181397A1 (en) 2012-05-30 2013-12-05 Vascular Access Technologies, Inc. Transvascular access device and method
US9241707B2 (en) 2012-05-31 2016-01-26 Abbott Cardiovascular Systems, Inc. Systems, methods, and devices for closing holes in body lumens
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US9936951B2 (en) 2013-03-12 2018-04-10 Covidien Lp Interchangeable tip reload
US20140263558A1 (en) * 2013-03-15 2014-09-18 Cardica, Inc. Extended curved tip for surgical apparatus
US9700312B2 (en) 2014-01-28 2017-07-11 Covidien Lp Surgical apparatus
US9936952B2 (en) 2014-02-03 2018-04-10 Covidien Lp Introducer assembly for a surgical fastener applying apparatus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099827A (en) * 1989-12-13 1992-03-31 Richard Wolf Gmbh Instrument set for closing opened body organs, wounds or the like
US5156608A (en) * 1990-07-30 1992-10-20 Hans Troidl Clip applicator for ligature clips
US5209756A (en) * 1989-11-03 1993-05-11 Bahaa Botros Seedhom Ligament fixation staple

Family Cites Families (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2275167A (en) 1939-04-26 1942-03-03 Bierman William Electrosurgical instrument
US2888928A (en) 1957-04-15 1959-06-02 Seiger Harry Wright Coagulating surgical instrument
US3490442A (en) 1966-02-09 1970-01-20 Hellige & Co Gmbh F Electrode with contact-forming suction cup means
GB1260919A (en) 1969-02-21 1972-01-19 Spitalul Clinic De Obstetrica Device for collecting biocurrents of the foetal heart
US3906955A (en) 1974-05-06 1975-09-23 Richard R Roberts Surgical cauterizing tool having suction means
GB1550676A (en) 1976-07-07 1979-08-15 Vickers Ltd Sensing probe for attachment to a body
US4326529A (en) 1978-05-26 1982-04-27 The United States Of America As Represented By The United States Department Of Energy Corneal-shaping electrode
US4307720A (en) 1979-07-26 1981-12-29 Weber Jr Jaroy Electrocautery apparatus and method and means for cleaning the same
US4562838A (en) 1981-01-23 1986-01-07 Walker William S Electrosurgery instrument
US4809695A (en) * 1981-10-21 1989-03-07 Owen M. Gwathmey Suturing assembly and method
US4485817A (en) 1982-05-28 1984-12-04 United States Surgical Corporation Surgical stapler apparatus with flexible shaft
US4473077A (en) 1982-05-28 1984-09-25 United States Surgical Corporation Surgical stapler apparatus with flexible shaft
GB8316194D0 (en) 1983-06-14 1983-07-20 Medeci Developments Ltd Electrode holders for current therapy
US4938218A (en) 1983-08-30 1990-07-03 Nellcor Incorporated Perinatal pulse oximetry sensor
EP0135840A3 (en) 1983-08-30 1986-06-11 Nellcor Incorporated Perinatal oximeter
USRE33925E (en) 1984-05-22 1992-05-12 Cordis Corporation Electrosurgical catheter aned method for vascular applications
US4682596A (en) 1984-05-22 1987-07-28 Cordis Corporation Electrosurgical catheter and method for vascular applications
US4645865A (en) * 1984-06-29 1987-02-24 Electro Nite Co. High temperature protection sleeve
FI861399A (en) 1985-04-26 1986-10-27 Astra Tech Ab Vakuumfixerad haollare Foer medicinskt bruk.
DE3672496D1 (en) 1986-10-22 1990-08-09 Fukuda Denshi Kk Case for an EKG electrode.
US4919129A (en) 1987-11-30 1990-04-24 Celebration Medical Products, Inc. Extendable electrocautery surgery apparatus and method
US4884567A (en) 1987-12-03 1989-12-05 Dimed Inc. Method for transvenous implantation of objects into the pericardial space of patients
US4911159A (en) 1988-11-21 1990-03-27 Johnson Jeffrey W Electrosurgical instrument with electrical contacts between the probe and the probe holder
FR2641003B1 (en) 1988-12-23 1991-04-05 Tech Milieu Ionisant
US5125928A (en) 1989-04-13 1992-06-30 Everest Medical Corporation Ablation catheter with selectively deployable electrodes
US5078717A (en) 1989-04-13 1992-01-07 Everest Medical Corporation Ablation catheter with selectively deployable electrodes
US4976711A (en) 1989-04-13 1990-12-11 Everest Medical Corporation Ablation catheter with selectively deployable electrodes
US5057107A (en) 1989-04-13 1991-10-15 Everest Medical Corporation Ablation catheter with selectively deployable electrodes
US5055100A (en) 1989-06-19 1991-10-08 Eugene Olsen Suction attachment for electrosurgical instruments or the like
US5056517A (en) 1989-07-24 1991-10-15 Consiglio Nazionale Delle Ricerche Biomagnetically localizable multipurpose catheter and method for magnetocardiographic guided intracardiac mapping, biopsy and ablation of cardiac arrhythmias
GB9008764D0 (en) 1990-04-19 1990-06-13 Egnell Ameda Ltd A resilient suction cup
US5171311A (en) 1990-04-30 1992-12-15 Everest Medical Corporation Percutaneous laparoscopic cholecystectomy instrument
US5071418A (en) 1990-05-16 1991-12-10 Joseph Rosenbaum Electrocautery surgical scalpel
WO1992004864A1 (en) 1990-09-26 1992-04-02 Merwe Marius V D Monitoring device
US5042707A (en) * 1990-10-16 1991-08-27 Taheri Syde A Intravascular stapler, and method of operating same
EP0516026A1 (en) * 1991-05-28 1992-12-02 Takeda Chemical Industries, Ltd. Hydrogel and method of producing same
US5195959A (en) 1991-05-31 1993-03-23 Paul C. Smith Electrosurgical device with suction and irrigation
US5196007A (en) 1991-06-07 1993-03-23 Alan Ellman Electrosurgical handpiece with activator
US5584803A (en) * 1991-07-16 1996-12-17 Heartport, Inc. System for cardiac procedures
WO1993005705A1 (en) 1991-09-19 1993-04-01 Surgicraft Limited A device for use in monitoring electric signals generated by the human body
US6832996B2 (en) 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
US5242456A (en) * 1991-11-21 1993-09-07 Kensey Nash Corporation Apparatus and methods for clamping tissue and reflecting the same
US5197963A (en) 1991-12-02 1993-03-30 Everest Medical Corporation Electrosurgical instrument with extendable sheath for irrigation and aspiration
WO1993015791A1 (en) 1992-02-12 1993-08-19 Dimed, Incorporated System for access to pericardial space
US5295955A (en) 1992-02-14 1994-03-22 Amt, Inc. Method and apparatus for microwave aided liposuction
WO1993021844A1 (en) 1992-04-23 1993-11-11 Scimed Life Systems, Inc. Apparatus and method for sealing vascular punctures
DE69319789D1 (en) 1992-05-21 1998-08-27 Pacesetter Ab electrode assembly
JPH0647050A (en) * 1992-06-04 1994-02-22 Olympus Optical Co Ltd Tissue suture and ligature device
US5324284A (en) 1992-06-05 1994-06-28 Cardiac Pathways, Inc. Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method
US5336252A (en) 1992-06-22 1994-08-09 Cohen Donald M System and method for implanting cardiac electrical leads
EP0647147B1 (en) 1992-06-26 2000-03-15 Schneider (Usa) Inc., Catheter with expandable wire mesh tip
WO1994002077A3 (en) 1992-07-15 1994-04-14 Angelase Inc Ablation catheter system
US5370675A (en) 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US5309910A (en) 1992-09-25 1994-05-10 Ep Technologies, Inc. Cardiac mapping and ablation systems
US5520700A (en) 1992-11-13 1996-05-28 Technion Research & Development Foundation, Ltd. Stapler device particularly useful in medical suturing
US6036699A (en) 1992-12-10 2000-03-14 Perclose, Inc. Device and method for suturing tissue
US5571215A (en) 1993-02-22 1996-11-05 Heartport, Inc. Devices and methods for intracardiac procedures
US5797960A (en) 1993-02-22 1998-08-25 Stevens; John H. Method and apparatus for thoracoscopic intracardiac procedures
US5320630A (en) * 1993-02-23 1994-06-14 Munir Ahmed Endoscopic ligating instrument for applying elastic bands
CA2192819A1 (en) * 1994-06-17 1995-12-28 Christopher Francis Heck Surgical stapling instrument and method thereof
US6325798B1 (en) 1998-02-19 2001-12-04 Curon Medical, Inc. Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions
US5505730A (en) 1994-06-24 1996-04-09 Stuart D. Edwards Thin layer ablation apparatus
US6123715A (en) 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
US5730742A (en) 1994-08-04 1998-03-24 Alto Development Corporation Inclined, flared, thermally-insulated, anti-clog tip for electrocautery suction tubes
US5972023A (en) * 1994-08-15 1999-10-26 Eva Corporation Implantation device for an aortic graft method of treating aortic aneurysm
US5665109A (en) * 1994-12-29 1997-09-09 Yoon; Inbae Methods and apparatus for suturing tissue
US6063081A (en) 1995-02-22 2000-05-16 Medtronic, Inc. Fluid-assisted electrocautery device
US7435247B2 (en) 1998-08-11 2008-10-14 Arthrocare Corporation Systems and methods for electrosurgical tissue treatment
US5709224A (en) 1995-06-07 1998-01-20 Radiotherapeutics Corporation Method and device for permanent vessel occlusion
US6456865B2 (en) 1995-06-08 2002-09-24 Ilan Zadik Samson Non-invasive medical probe
NL1001890C2 (en) 1995-12-13 1997-06-17 Cordis Europ Catheter with plate-shaped electrode array.
US5814065A (en) * 1996-02-09 1998-09-29 Cordis Corporation Suture delivery tool
US5624413A (en) * 1996-02-23 1997-04-29 Medical Components, Inc. Method for inserting a multiple catheter assembly
US6149660A (en) * 1996-04-22 2000-11-21 Vnus Medical Technologies, Inc. Method and apparatus for delivery of an appliance in a vessel
US5676670A (en) * 1996-06-14 1997-10-14 Beth Israel Deaconess Medical Center Catheter apparatus and method for creating a vascular bypass in-vivo
US5855312A (en) * 1996-07-25 1999-01-05 Toledano; Haviv Flexible annular stapler for closed surgery of hollow organs
US5902310A (en) * 1996-08-12 1999-05-11 Ethicon Endo-Surgery, Inc. Apparatus and method for marking tissue
US6482224B1 (en) 1996-08-22 2002-11-19 The Trustees Of Columbia University In The City Of New York Endovascular flexible stapling device
WO2001005306A1 (en) 1999-07-19 2001-01-25 Epicor, Inc. Apparatus and method for ablating tissue
US5827268A (en) 1996-10-30 1998-10-27 Hearten Medical, Inc. Device for the treatment of patent ductus arteriosus and method of using the device
US5781443A (en) * 1996-10-30 1998-07-14 Street; William L. Apparatus for use in parts assembly
US6004341A (en) * 1996-12-05 1999-12-21 Loma Linda University Medical Center Vascular wound closure device
US5972024A (en) * 1996-12-24 1999-10-26 Metacardia, Inc. Suture-staple apparatus and method
JP3134288B2 (en) 1997-01-30 2001-02-13 株式会社ニッショー Intracardiac suture surgical instruments
US5861005A (en) * 1997-02-11 1999-01-19 X-Site, L.L.C. Arterial stapling device
WO1999018864A1 (en) 1997-10-10 1999-04-22 Hearten Medical, Inc. A balloon catheter for abrading a patent foramen ovale and method of using the balloon catheter
WO1999018862A1 (en) 1997-10-10 1999-04-22 Hearten Medical, Inc. A catheter device for abrading a patent foramen ovale and method of using the device
US5944738A (en) 1998-02-06 1999-08-31 Aga Medical Corporation Percutaneous catheter directed constricting occlusion device
JP3799810B2 (en) 1998-03-30 2006-07-19 ニプロ株式会社 Closure plugs and catheter assembly for transcatheter surgery
US6409722B1 (en) 1998-07-07 2002-06-25 Medtronic, Inc. Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
DE69927035T2 (en) 1998-08-03 2006-06-08 Anson Medical Ltd, Abingdon Devices for the repair of arteries
EP1104261A1 (en) 1998-08-13 2001-06-06 Keravision, Inc. Corneal electrosurgical probe with a variable-height active site
US6156032A (en) 1998-09-30 2000-12-05 Scimed Life Systems, Inc. Method for causing a stricture of a body passageway
US5919200A (en) 1998-10-09 1999-07-06 Hearten Medical, Inc. Balloon catheter for abrading a patent foramen ovale and method of using the balloon catheter
US7128073B1 (en) 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US6606523B1 (en) 1999-04-14 2003-08-12 Transneuronix Inc. Gastric stimulator apparatus and method for installing
US6325796B1 (en) * 1999-05-04 2001-12-04 Afx, Inc. Microwave ablation instrument with insertion probe
US6712836B1 (en) 1999-05-13 2004-03-30 St. Jude Medical Atg, Inc. Apparatus and methods for closing septal defects and occluding blood flow
US7526342B2 (en) 1999-08-10 2009-04-28 Maquet Cardiovascular Llc Apparatus for endoscopic cardiac mapping and lead placement
EP1210014A1 (en) 1999-09-07 2002-06-05 Microvena Corporation Retrievable septal defect closure device
US6231561B1 (en) 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US20030069570A1 (en) 1999-10-02 2003-04-10 Witzel Thomas H. Methods for repairing mitral valve annulus percutaneously
US6551303B1 (en) 1999-10-27 2003-04-22 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6383198B1 (en) 1999-12-07 2002-05-07 Scimed Life System, Inc. Flexible vacuum grabber for holding lesions
US6790218B2 (en) 1999-12-23 2004-09-14 Swaminathan Jayaraman Occlusive coil manufacture and delivery
GB0002970D0 (en) 2000-02-09 2000-03-29 Anson Medical Ltd Fixator for the repair of articles
US6558314B1 (en) 2000-02-11 2003-05-06 Iotek, Inc. Devices and method for manipulation of organ tissue
US6641604B1 (en) 2000-02-11 2003-11-04 Iotek, Inc. Devices and method for manipulation of organ tissue
US6650923B1 (en) 2000-04-13 2003-11-18 Ev3 Sunnyvale, Inc. Method for accessing the left atrium of the heart by locating the fossa ovalis
US6551344B2 (en) 2000-04-26 2003-04-22 Ev3 Inc. Septal defect occluder
US6514250B1 (en) 2000-04-27 2003-02-04 Medtronic, Inc. Suction stabilized epicardial ablation devices
US6558382B2 (en) 2000-04-27 2003-05-06 Medtronic, Inc. Suction stabilized epicardial ablation devices
WO2001082811A1 (en) 2000-04-27 2001-11-08 Medtronic, Inc. System and method for assessing transmurality of ablation lesions
US6352543B1 (en) 2000-04-29 2002-03-05 Ventrica, Inc. Methods for forming anastomoses using magnetic force
US6645225B1 (en) 2000-11-01 2003-11-11 Alvan W. Atkinson Method and apparatus for plugging a patent foramen ovale formed in the heart
US6846319B2 (en) 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
US20020143322A1 (en) 2001-01-23 2002-10-03 Haghighi Ali Z. Apparatus and method for shrinking collagen
US6776784B2 (en) 2001-09-06 2004-08-17 Core Medical, Inc. Clip apparatus for closing septal defects and methods of use
US6702835B2 (en) 2001-09-07 2004-03-09 Core Medical, Inc. Needle apparatus for closing septal defects and methods for using such apparatus
US6652518B2 (en) 2001-09-28 2003-11-25 Ethicon, Inc. Transmural ablation tool and method
US6907297B2 (en) 2001-09-28 2005-06-14 Ethicon, Inc. Expandable intracardiac return electrode and method of use
US6669693B2 (en) 2001-11-13 2003-12-30 Mayo Foundation For Medical Education And Research Tissue ablation device and methods of using
US6849075B2 (en) 2001-12-04 2005-02-01 Estech, Inc. Cardiac ablation devices and methods
EP1467661A4 (en) 2001-12-19 2008-11-05 Nmt Medical Inc Septal occluder and associated methods
EP1471835A4 (en) 2002-01-14 2008-03-19 Nmt Medical Inc Patent foramen ovale (pfo) closure method and device
US6749621B2 (en) 2002-02-21 2004-06-15 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
EP1487353A4 (en) 2002-03-25 2008-04-16 Nmt Medical Inc Patent foramen ovale (pfo) closure clips
US7976564B2 (en) 2002-05-06 2011-07-12 St. Jude Medical, Cardiology Division, Inc. PFO closure devices and related methods of use
US20040098042A1 (en) 2002-06-03 2004-05-20 Devellian Carol A. Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
US7063698B2 (en) 2002-06-14 2006-06-20 Ncontact Surgical, Inc. Vacuum coagulation probes
US20040044391A1 (en) 2002-08-29 2004-03-04 Stephen Porter Device for closure of a vascular defect and method of treating the same
US6755790B2 (en) 2002-10-14 2004-06-29 Medtronic, Inc. Transseptal access tissue thickness sensing dilator devices and methods for fabricating and using same
US7172562B2 (en) 2002-11-22 2007-02-06 Mckinley Laurence M System, method and apparatus for locating, measuring and evaluating the enlargement of a foramen
US9017373B2 (en) 2002-12-09 2015-04-28 W.L. Gore & Associates, Inc. Septal closure devices
US6960224B2 (en) 2003-01-22 2005-11-01 Cardia, Inc. Laminated sheets for use in a fully retrievable occlusion device
EP1596723A2 (en) 2003-02-04 2005-11-23 ev3 Sunnyvale, Inc. Patent foramen ovale closure system
US8021359B2 (en) 2003-02-13 2011-09-20 Coaptus Medical Corporation Transseptal closure of a patent foramen ovale and other cardiac defects
DE602004018282D1 (en) 2003-03-17 2009-01-22 Ev3 Endovascular Inc Stent with laminated thin-film composite
US20040267306A1 (en) 2003-04-11 2004-12-30 Velocimed, L.L.C. Closure devices, related delivery methods, and related methods of use
ES2428967T3 (en) 2003-07-14 2013-11-12 W.L. Gore & Associates, Inc. tubular closure device patent foramen ovale (PFO) retention system
US20050055050A1 (en) 2003-07-24 2005-03-10 Alfaro Arthur A. Intravascular occlusion device
US7438714B2 (en) 2003-09-12 2008-10-21 Boston Scientific Scimed, Inc. Vacuum-based catheter stabilizer
WO2005027753A1 (en) 2003-09-19 2005-03-31 St. Jude Medical, Inc. Apparatus and methods for tissue gathering and securing
US20050065509A1 (en) 2003-09-22 2005-03-24 Scimed Life Systems, Inc. Flat electrode arrays for generating flat lesions
US7462188B2 (en) 2003-09-26 2008-12-09 Abbott Laboratories Device and method for suturing intracardiac defects
JP2007527272A (en) 2003-10-10 2007-09-27 コヒーレックス メディカル インコーポレイテッド Patent foramen ovale (pfo) closure device, delivery device, and related methods and systems
EP2213244A1 (en) 2003-10-24 2010-08-04 ev3 Endovascular, Inc. Patent foramen ovale closure system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5209756A (en) * 1989-11-03 1993-05-11 Bahaa Botros Seedhom Ligament fixation staple
US5099827A (en) * 1989-12-13 1992-03-31 Richard Wolf Gmbh Instrument set for closing opened body organs, wounds or the like
US5156608A (en) * 1990-07-30 1992-10-20 Hans Troidl Clip applicator for ligature clips

Cited By (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9468437B2 (en) 1996-08-22 2016-10-18 The Trustees Of Columbia University In The City Of New York Endovascular flexible stapling device
US8133239B2 (en) 1997-06-27 2012-03-13 The Trustees Of Columbia University In The City Of New York Method and apparatus for circulatory valve repair
US7509959B2 (en) 1997-06-27 2009-03-31 The Trustees Of Columbia University In The City Of New York Method and apparatus for circulatory valve repair
US7758596B2 (en) 1997-06-27 2010-07-20 The Trustees Of Columbia University In The City Of New York Method and apparatus for circulatory valve repair
US6461366B1 (en) 1997-09-12 2002-10-08 Evalve, Inc. Surgical device for connecting soft tissue
US6770083B2 (en) 1997-09-12 2004-08-03 Evalve, Inc. Surgical device for connecting soft tissue
US9510837B2 (en) 1997-09-12 2016-12-06 Evalve, Inc. Surgical device for connecting soft tissue
US6695866B1 (en) 1998-07-15 2004-02-24 St. Jude Medical, Inc. Mitral and tricuspid valve repair
US6165183A (en) * 1998-07-15 2000-12-26 St. Jude Medical, Inc. Mitral and tricuspid valve repair
WO2000003759A3 (en) * 1998-07-15 2000-04-20 St Jude Medical Mitral and tricuspid valve repair
US6629534B1 (en) 1999-04-09 2003-10-07 Evalve, Inc. Methods and apparatus for cardiac valve repair
US7811296B2 (en) 1999-04-09 2010-10-12 Evalve, Inc. Fixation devices for variation in engagement of tissue
US6752813B2 (en) 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
US9510829B2 (en) 1999-04-09 2016-12-06 Evalve, Inc. Fixation devices, systems and methods for engaging tissue
US9044246B2 (en) 1999-04-09 2015-06-02 Abbott Vascular Inc. Methods and devices for capturing and fixing leaflets in valve repair
US7682319B2 (en) 1999-04-09 2010-03-23 Evalve, Inc. Steerable access sheath and methods of use
US6743239B1 (en) 2000-05-25 2004-06-01 St. Jude Medical, Inc. Devices with a bendable tip for medical procedures
US7678132B2 (en) 2001-09-06 2010-03-16 Ovalis, Inc. Systems and methods for treating septal defects
US7686828B2 (en) 2001-09-06 2010-03-30 Ovalis, Inc. Systems and methods for treating septal defects
US7740640B2 (en) 2001-09-06 2010-06-22 Ovalis, Inc. Clip apparatus for closing septal defects and methods of use
US8758401B2 (en) 2001-09-06 2014-06-24 ProMed, Inc. Systems and methods for treating septal defects
US8747483B2 (en) 2001-09-07 2014-06-10 ProMed, Inc. Needle apparatus for closing septal defects and methods for using such apparatus
US8070826B2 (en) 2001-09-07 2011-12-06 Ovalis, Inc. Needle apparatus for closing septal defects and methods for using such apparatus
US7871433B2 (en) 2001-12-08 2011-01-18 Lattouf Omar M Treatments for a patient with congestive heart failure
US7373207B2 (en) 2001-12-08 2008-05-13 Lattouf Omar M Treatments for a patient with congestive heart failure
US9999442B2 (en) 2001-12-08 2018-06-19 Trans Cardiac Therapeutics, Inc. Methods for accessing a left ventricle
US7513908B2 (en) 2001-12-08 2009-04-07 Lattouf Omar M Treatments for a patient with congestive heart failure
US8029565B2 (en) 2001-12-08 2011-10-04 Lattouf Omar M Treatment for a patient with congestive heart failure
US7534260B2 (en) 2001-12-08 2009-05-19 Lattouf Omar M Treatments for a patient with congestive heart failure
US7967840B2 (en) 2001-12-19 2011-06-28 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
US7048754B2 (en) 2002-03-01 2006-05-23 Evalve, Inc. Suture fasteners and methods of use
US9241695B2 (en) 2002-03-25 2016-01-26 W.L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure clips
US9216014B2 (en) 2002-06-03 2015-12-22 W.L. Gore & Associates, Inc. Device with biological tissue scaffold for percutaneous closure of an intracardiac defect and methods thereof
US9028527B2 (en) 2002-06-05 2015-05-12 W.L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with radial and circumferential support
US9949829B2 (en) 2002-06-13 2018-04-24 Ancora Heart, Inc. Delivery devices and methods for heart valve repair
US9226825B2 (en) 2002-06-13 2016-01-05 Guided Delivery Systems, Inc. Delivery devices and methods for heart valve repair
US9468528B2 (en) 2002-06-13 2016-10-18 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US9636107B2 (en) 2002-06-13 2017-05-02 Ancora Heart, Inc. Devices and methods for heart valve repair
US6986775B2 (en) 2002-06-13 2006-01-17 Guided Delivery Systems, Inc. Devices and methods for heart valve repair
US9072513B2 (en) 2002-06-13 2015-07-07 Guided Delivery Systems Inc. Methods and devices for termination
US9017373B2 (en) 2002-12-09 2015-04-28 W.L. Gore & Associates, Inc. Septal closure devices
US7914527B2 (en) 2003-03-27 2011-03-29 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US8038672B2 (en) 2003-03-27 2011-10-18 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US8038669B2 (en) 2003-03-27 2011-10-18 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
EP2455037A1 (en) 2003-03-27 2012-05-23 Terumo Kabushiki Kaisha Methods and apparatus for treatment of patent foramen ovale
US8057469B2 (en) 2003-03-27 2011-11-15 Terumo Kabushiki Kaisha Methods and apparatus for treatment of patent foramen ovale
US8075554B2 (en) 2003-03-27 2011-12-13 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US8070747B2 (en) 2003-03-27 2011-12-06 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
WO2004087235A2 (en) 2003-03-27 2004-10-14 Cierra, Inc. Methods and apparatus for treatment of patent foramen ovale
US8021362B2 (en) 2003-03-27 2011-09-20 Terumo Kabushiki Kaisha Methods and apparatus for closing a layered tissue defect
US7972330B2 (en) 2003-03-27 2011-07-05 Terumo Kabushiki Kaisha Methods and apparatus for closing a layered tissue defect
US8852181B2 (en) 2003-03-27 2014-10-07 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of anatomic tissue defects
US8038671B2 (en) 2003-03-27 2011-10-18 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US7922716B2 (en) 2003-03-27 2011-04-12 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of anatomic tissue defects
US8038673B2 (en) 2003-03-27 2011-10-18 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US8052678B2 (en) 2003-03-27 2011-11-08 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of patent foramen ovale
US9149263B2 (en) 2003-07-14 2015-10-06 W. L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9326759B2 (en) 2003-07-14 2016-05-03 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
US8114123B2 (en) 2003-09-19 2012-02-14 St. Jude Medical, Inc. Apparatus and methods for tissue gathering and securing
US8292910B2 (en) 2003-11-06 2012-10-23 Pressure Products Medical Supplies, Inc. Transseptal puncture apparatus
US8992556B2 (en) 2003-11-06 2015-03-31 Pressure Products Medical Supplies, Inc. Transseptal puncture apparatus
US8157829B2 (en) 2003-11-06 2012-04-17 Pressure Products Medical Supplies, Inc. Transseptal puncture apparatus
US8568431B2 (en) 2004-03-03 2013-10-29 W.L. Gore & Associates, Inc. Delivery/recovery system for septal occluder
US8945158B2 (en) 2004-03-03 2015-02-03 W.L. Gore & Associates, Inc. Delivery/recovery system for septal occluder
US8568447B2 (en) 2004-05-06 2013-10-29 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US7842069B2 (en) 2004-05-07 2010-11-30 Nmt Medical, Inc. Inflatable occluder
US9545247B2 (en) 2004-05-07 2017-01-17 W.L. Gore & Associates, Inc. Catching mechanisms for tubular septal occluder
US8133221B2 (en) 2004-06-21 2012-03-13 Terumo Kabushiki Kaisha Energy based devices and methods for treatment of anatomic tissue defects
US8920434B2 (en) 2005-03-02 2014-12-30 St. Jude Medical, Cardiology Division, Inc. Remote body tissue engaging methods and apparatus
US8109274B2 (en) 2005-04-11 2012-02-07 Terumo Kabushiki Kaisha Methods and electrode apparatus to achieve a closure of a layered tissue defect
US8579936B2 (en) 2005-07-05 2013-11-12 ProMed, Inc. Centering of delivery devices with respect to a septal defect
US7846179B2 (en) 2005-09-01 2010-12-07 Ovalis, Inc. Suture-based systems and methods for treating septal defects
US9084603B2 (en) 2005-12-22 2015-07-21 W.L. Gore & Associates, Inc. Catch members for occluder devices
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
US9949728B2 (en) 2007-04-05 2018-04-24 W.L. Gore & Associates, Inc. Septal closure device with centering mechanism
US9005242B2 (en) 2007-04-05 2015-04-14 W.L. Gore & Associates, Inc. Septal closure device with centering mechanism
US9138562B2 (en) 2007-04-18 2015-09-22 W.L. Gore & Associates, Inc. Flexible catheter system
US9706996B2 (en) 2008-02-06 2017-07-18 Ancora Heart, Inc. Multi-window guide tunnel
US9474517B2 (en) 2008-03-07 2016-10-25 W. L. Gore & Associates, Inc. Heart occlusion devices
US9636106B2 (en) 2008-10-10 2017-05-02 Ancora Heart, Inc. Termination devices and related methods
US9616197B2 (en) 2009-01-20 2017-04-11 Ancora Heart, Inc. Anchor deployment devices and related methods
US9060858B2 (en) 2009-09-15 2015-06-23 Evalve, Inc. Methods, systems and devices for cardiac valve repair
US9861350B2 (en) 2010-09-03 2018-01-09 Ancora Heart, Inc. Devices and methods for anchoring tissue
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system

Also Published As

Publication number Publication date Type
US7794474B2 (en) 2010-09-14 grant
US20120095490A1 (en) 2012-04-19 application
US20150265274A1 (en) 2015-09-24 application
US20020099389A1 (en) 2002-07-25 application
US9610078B2 (en) 2017-04-04 grant
US9468437B2 (en) 2016-10-18 grant
US20150265273A1 (en) 2015-09-24 application
US20080272174A1 (en) 2008-11-06 application
US20120193391A1 (en) 2012-08-02 application
US6482224B1 (en) 2002-11-19 grant
US20080249565A1 (en) 2008-10-09 application
US20170172569A1 (en) 2017-06-22 application
US8048110B2 (en) 2011-11-01 grant
US8167905B2 (en) 2012-05-01 grant

Similar Documents

Publication Publication Date Title
US5417699A (en) Device and method for the percutaneous suturing of a vascular puncture site
US7736388B2 (en) Fixation devices, systems and methods for engaging tissue
US6348064B1 (en) Wound site management and wound closure device
US5042707A (en) Intravascular stapler, and method of operating same
US6517553B2 (en) Device and method for suturing of internal puncture sites
US5891159A (en) Automatic purse string suture device
US6780197B2 (en) Apparatus and methods for delivering a vascular closure device to a body lumen
US6514263B1 (en) Helical needle and suture combination having a strain relief element
US5980455A (en) Method for manipulating a tissue structure within a thoracic cavity
US7241310B2 (en) Method and apparatus for reducing mitral regurgitation
US6391048B1 (en) Integrated vascular device with puncture site closure component and sealant and methods of use
US7029480B2 (en) Device and method for suturing of internal puncture sites
US6569196B1 (en) System for minimally invasive insertion of a bioprosthetic heart valve
US5951567A (en) Introducer for channel forming device
US7935128B2 (en) Remotely-reloadable suturing device
US6520973B1 (en) Anastomosis device having an improved needle driver
US20060276684A1 (en) Device and method for treating congestive heart failure
US7699892B2 (en) Minimally invasive procedure for implanting an annuloplasty device
US20010025171A1 (en) Transventricular implant tools and devices
US6746426B1 (en) Transluminally deliverable vascular blockers and methods for facilitating retrograde flow of arterial blood through veins
US6312447B1 (en) Devices and methods for percutaneous mitral valve repair
US20040059351A1 (en) Methods and apparatus for atrioventricular valve repair
US20090163934A1 (en) Detachment mechanism for implantable fixation devices
US6010514A (en) Suturing assembly and method of use
US20040116897A1 (en) Minimally invasive bypass system and related methods

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU CA JP MX US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
COP Corrected version of pamphlet

Free format text: PAGES 1-9, DESCRIPTION, REPLACED BY NEW PAGES 1-9; PAGES 10-14, CLAIMS, REPLACED BY NEW PAGES 10-14; PAGES 1/2-2/2, DRAWINGS, REPLACED BY NEW PAGES 1/2-2/2; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

NENP Non-entry into the national phase in:

Ref country code: JP

Ref document number: 1998510992

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 09242969

Country of ref document: US

NENP Non-entry into the national phase in:

Ref country code: CA

122 Ep: pct application non-entry in european phase