WO1997044109A1 - Device and installation for microwave extracting of organic compounds from a sample - Google Patents
Device and installation for microwave extracting of organic compounds from a sample Download PDFInfo
- Publication number
- WO1997044109A1 WO1997044109A1 PCT/FR1997/000883 FR9700883W WO9744109A1 WO 1997044109 A1 WO1997044109 A1 WO 1997044109A1 FR 9700883 W FR9700883 W FR 9700883W WO 9744109 A1 WO9744109 A1 WO 9744109A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- solvent
- container
- reservoir
- extraction
- cartridge
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/44—Sample treatment involving radiation, e.g. heat
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0211—Solvent extraction of solids in combination with an electric or magnetic field
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0215—Solid material in other stationary receptacles
- B01D11/0219—Fixed bed of solid material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/14—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
Definitions
- the present invention relates generally to the extraction of organic compounds present in samples, and more particularly to a device for extracting, via a solvent, organic compounds from a sample, coupled to a container containing said solvent and subjected to microwave heating.
- the invention also relates to a Soxlhet type extraction installation of organic compounds from a sample, which comprises such an extraction device.
- the extraction under microwave heating of organic compounds from a sample is carried out according to an extraction method of the Soxtec type, according to which the extraction solvent and the sample to be treated are placed in the bottom of a container, which is connected in the upper part to a cooling system, said container being subjected to microwave heating for a determined period so that the organic compounds present in the sample are extracted in the solvent.
- the part of the solvent which evaporates under the microwave heating recondenses on contact with the refrigerant and thus falls back to the bottom of the container where the sample and the solvent containing the extracted compounds are located. .
- the present invention provides a new microwave-assisted extraction device which makes it possible to lighten the abovementioned extraction process by eliminating the filtration step and by reducing the time devoted to the step of reconcentrating the extract.
- the invention provides a new extraction device via a solvent for organic compounds in a sample, coupled to a container containing said solvent and subjected to microwave heating.
- This device comprises: - an elongated member carrying at one end engaged in the container a cartridge containing the sample to be treated, a cylindrical wall closed above, which surrounds a part of said elongated member emerging from the container so that an annular passage vapors is delimited between them, the lower part of said cylindrical wall opening tightly into the container, a solvent tank having an upper opening for the installation of a refrigerant system or a vapor suction system ,
- connection conduit which extends from the interior of the tank in a downwardly inclined direction, towards said elongated member to open into said annular passage of vapors and come into contact with said elongated member.
- the term “refrigerant system” is understood here to mean a conventional system cooled by a refrigerant fluid such as water, or an electronic Peltier effect system.
- a refrigerant fluid such as water
- an electronic Peltier effect system the use of the cartridge makes it possible to eliminate the step of filtration of the solvent containing the extract in which the sediment was found when a microwave extraction was carried out according to the aforementioned prior art.
- the elongate member is movably mounted to slide along its vertical axis inside said container. The vertical movement of raising and lowering of said elongated member can be carried out according to the invention automatically.
- the solvent can be evaporated in the device according to the invention, with or without removing the cartridge from said container, simply by raising said elongated member so that the cartridge is no longer immersed in the solvent comprising the extracted compounds, then heating said solvent so as to evaporate it and to refocus the extract.
- Solvent vapors can be removed via an extractor hood positioned in the upper opening of said tank.
- the use of the device according to the invention allows a saving of time of approximately 1 h 30 min compared to the extraction time according to the abovementioned conventional microwave extraction method.
- the elongated member can be slid into said container, so as to position the sediment contained in the cartridge after extraction above the solvent containing the extracted compounds, then makes it possible to carry out rinsing the sediment while continuing to heat after total extraction of the compounds, said solvent so that it continues to evaporate and recondense while passing through the sediment contained in the cartridge.
- provision may be made for the cylindrical wall and the connection duct to form a single piece.
- the reservoir and the connection conduit form a single piece.
- said cylindrical wall and the container form a single piece.
- Said single piece constituting the reservoir and the connection conduit can then advantageously be in the form of an elbow, the upper part of the elbow constituting said reservoir and the lower part of the elbow constituting said connection conduit.
- the elongated member is then a hollow rod.
- the solvent is evaporated by heating it under the action of a micro field. -waves, is assisted by a flow of nitrogen introduced directly into the solvent via the internal conduit of the rod.
- the reservoir has at its bottom a tap or a solenoid valve for the recovery outside of the solvent present in said reservoir.
- the elongated member is a solid rod or a wire.
- a wire instead of a solid rod as an elongated member may be advantageous for the production of a device according to the invention operating automatically, since the raising and lowering of the wire can easily be automated using a winding system of said wire.
- a solenoid valve is useful in an automated device according to the invention.
- the solvent used in the reservoir can be recovered and recycled for later extraction.
- the cylindrical wall has an upper end edge which delimits an opening in which a closure plug fits in which said rod is mounted in leaktight manner.
- the member extends the cylindrical wall, the reservoir and the connection conduit are made of glass.
- the present invention also provides a Soxlhet type extraction installation of organic compounds from a sample, which comprises a container containing an extraction solvent, heated by conventional heating means.
- This installation is characterized in that it comprises means for emitting microwaves in an application cavity delimited by an upper wall, a side wall and a lower wall, the upper wall of said cavity being provided with an opening. , bordered by a chimney forming a barrier to the propagation towards the outside of microwaves, for the introduction into said application cavity of a flask coupled to an extraction device according to the invention, so that the upper part of said cylindrical wall connected by said conduit for connection to said reservoir of said extraction device, is located outside said microwave application cavity, and said lower wall of said cavity comprising an orifice, bordered a chimney forming a barrier to the propagation to the outside of microwaves, allowing the passage of a first external tube which connects the bottom of said flask to said solvent container, this first external tube having a siphon shape, a second external tube being provided for connecting the reservoir of said extraction device to the solvent container.
- traditional heating is meant here any kind of heating which is not a microwave heating of the electric or gas heating type.
- the installation according to the invention advantageously makes it possible to better control the extraction operation by varying the traditional heating and the microwave heating independently as well as the solvent used.
- traditional heating makes it possible, among other things, to heat solvents which may be more or less transparent to the microwave field.
- FIG. 1 is a longitudinal sectional view of a first embodiment of an extraction device according to the invention coupled to a container
- - Figures 2a to 2c schematically show a variant of the first embodiment of the device represents in FIG. 1, at three successive stages of an extraction process
- FIGS. 3a to 3c show diagrammatically at three different stages of an extraction process
- a second embodiment of the extraction device according to the 'invention
- FIG. 5 is a schematic representation of an installation according to the present invention.
- a a represents an extraction device 100, via a solvent, of organic compounds from a sample.
- This extraction device 100 is coupled to a container 1 intended to contain said solvent and to be subjected to microwave heating.
- the extraction device 100 comprises an elongated member of axis X, here a rod 110 vertically engaged inside the container 1 along its axis. This rod 110 door at one end engaged in the container 1, a cartridge 120 containing the sample to be treated.
- the cartridge 120 is an extraction cartridge made of cellulose or any other suitable porous material. It is fixed by means of a support 111 mounted at the end of the rod 110. This support 111 is produced for example from polytetrafluoroethylene. A locking system 112 is engaged on the rod 110 so as to secure the cartridge 120 to the support 111. According to an alternative embodiment not shown, it is possible to provide that the cartridge is secured to the end of the rod by a magnet system , such a magnet system is advantageous in a device according to the invention operating automatically, because it allows the automatic installation and removal of the cartridge.
- said extraction device 100 has a cylindrical wall 130 which surrounds a part of the rod 110 which emerges from the container 1 so that an annular vapor passage 131 is delimited between said cylindrical wall and said rod.
- lugs 133 are provided to keep the rod 110 centered inside said cylindrical wall 130.
- This cylindrical wall 130 has, at the top, an end edge which delimits an opening 132 This opening 132 is hermetically closed by means of a rode stopper made of polytetrafluoroethylene for example. Inside this rode stopper, the rod 110 is engaged so that it is movably mounted to slide inside the container 1 along its axis X.I1 notes that the upward and downward movement of the rod along its axis X ⁇ ans the container, can be automated. To this end, the lapped bushing 160 has a seal for guiding the rod 110.
- the cylindrical wall 130 has at its lower end an opening which opens into the interior of the container 1.
- the adjustment of the cylindrical wall 130 has the interior of the container 1 is made in a sealed manner.
- the extraction device 100 also includes a solvent tank 140 comprising an upper opening 141 in which a running-in 143 is positioned for the installation of a refrigerant system or a vapor suction system.
- the refrigerant system is a refrigerant system such as water or an automatic Peltier effect system.
- the reservoir 140 has at its bottom a tap 142 for the recovery outside of the solvent present in said reservoir 140.
- a solenoid valve in place of the tap 142.
- a connection duct 150 is provided which extends from the inside of the reservoir 140 in a direction Y inclined downward relative to the axis X of the rod 110, in the direction of the rod 110, to open out. in said annular vapor passage 131 and come into contact with said rod 110.
- the cylindrical wall 1J0 comprises at the level of this connection duct 150 a widening for allowing part of the duct 150 to extend inside said annular passage of the vapors 131 and to come into contact with said rod 110 .
- the cylindrical wall 130 and the connection conduit 150 form a single piece.
- the reservoir and the connection conduit form a single piece, and that the cylindrical wall and the container form a single piece.
- FIGS. 2a to 2c three successive stages of a process for extracting organic compounds have been shown, here polycyclic aromatic compounds contained in a sample, using an alternative embodiment of the extraction device 100 shown in Figure 1.
- the container 1 and the cylindrical wall 130 form a single piece, the reservoir 140 and the connection conduit also forming a single piece.
- FIG. 2a shows the actual extraction step using said device 100.
- a microwave field with a power for example equal to 90 W is applied to the container 1 which contains a solvent S extraction and the rod 110 is positioned in the low position so that the cartridge 120 is immersed in said solvent S.
- the solvent Under the action of the microwave field, the solvent vaporizes and the solvent vapors propagate to the reservoir 140 where, in contact with the refrigerant 144, they recondense. The recondensed droplets are recovered in the reservoir 140.
- the solvent is vaporized either by direct absorption by the latter of microwave energy if said solvent is polar, or, if it is not sufficiently polar, by heat conduction via an element heated by the microwave energy, such as the container, the sample or any other element capable of heating under the direct action of microwaves.
- the valve 142 of the reservoir 140 is then in the closed position.
- the solvent flows along the rod 110 to descend into the cartridge 120 via a central conduit 111 'provided in the locking system 112 and the support 111 , and flow through the porous wall of said cartridge, into the bottom of container 1.
- the rod 110 is positioned in the high position so that the cartridge 120 is above the solvent S and we continue to apply at the bottom of the container 1, the microwave field of the same power, of so that the solvent continues to vaporize and recondense on contact with the refrigerant 144 in the reservoir 140 with its tap 142 closed.
- the solvent droplets recondensed and recovered in the tank, slide along the rod and rinse the sediment present in the raised cartridge 120.
- the cartridge is placed in a basket with a sealed wall, fixed at the end of the rod, so that it remains between said sealed wall and said cartridge. , a gap in which the solvent flows through the cartridge, said basket comprising in the upper part a system for discharging solvent in the event of an overflow.
- Figure 2c shows the next step which is a step of reconcentrating the extract in the container.
- the cartridge 120 is always positioned in the high position, that is to say above the solvent.
- the tap 142 is then opened and a microwave field of the same power is applied to the bottom of the container 1.
- the solvent vaporizes and recondenses in the reservoir 140 under the action of the refrigerant 144, then flows via the tap 142 through a tube 2 connected to said tap, so as to be collected in a graduated container 3.
- the rod, the reservoir, the cylindrical wall and the connection conduit are made either of glass, or of polytetrafluoroethylene or else of quartz for example.
- the glass rod is a solid rod.
- the solid rod is replaced by a wire, which can be automatically wound and unrolls outside the device to allow it to descend and rise ⁇ ans said container.
- the adaptation of the refrigerant system 144 to the running-in provided in the upper opening of the tank must be such that good tightness is observed and the refrigerant is not in contact with the walls of the solvent tank.
- FIGS. 3a to 3c three stages of operation of a second embodiment have been shown in the extraction device 100 according to the invention.
- the upper part of the elbow constitutes the reservoir 140 and the lower part of the elbow constitutes the conduit of connection 150.
- the reservoir 140 does not have a tap at its bottom.
- the rod 110 is a hollow rod.
- the cylindrical wall 130 and the container 101 form a single piece.
- these two elements are two different parts coupled together.
- FIG. 3a shows the actual extraction of the polycyclic organic compounds contained in the matrix positioned in the cartridge 120, under the action of the microwave field applied to the bottom of the container 1 which contains the cartridge 120 positioned in position low at the end of the rod 110 so that it bathes in the solvent S.
- the microwave field is for example of a power of 30 W.
- the solvent S vaporizes and the solvent vapors rise in the reservoir 140 or they recondense.
- the recondensed solvent droplets then fall via the connection duct 150 into the container, flowing along the rod 110 to pass through the cartridge 120 and reach the bottom of the container.
- the rod 110 is raised in the high position so that the cartridge 120 is placed above the quantity of solvent S contained in the bottom of container 1, while the solvent field S at the bottom of container 1 is continued to apply the microwave field.
- This step shown in Figure 3b is the rinsing step. Under the action in the microwave field, the heated solvent S evaporates and rises to the reservoir 140 via the connection conduit 150.
- the solvent droplets recondensed via the refrigerant 144 slide via the connection duct 150, along the rod 110 and rinse the sediment located in the raised cartridge 120, before falling back into the bottom of the container 1.
- the cartridge 120 is then removed from the container 1.
- a microwave field is applied to the bottom of the container 1 and a flow of nitrogen is introduced from the inside of the rod 110 according to arrow A.
- the solvent vapors formed under the microwave heating are evacuated towards the connection duct 150 and sucked in according to arrow B with the aid of an extractor hood positioned in the upper opening of the tank.
- Such a magnetic stirring bar allows homogenization of the sample and of the solvent during the extraction step.
- the contact and exchange surface between the sample containing the compounds to be extracted and the solution is increased during the extraction step.
- the duration of the extraction is reduced while maintaining a good extraction yield.
- Agitation advantageously avoids the possible phenomena of over-boiling of the heated solvent during extraction, such over-boiling causing a O 97/44109 PC17FR97 / 00883 sudden unwanted rise of the solvent in the container.
- the magnetic bar can advantageously absorb a non-negligible amount of microwave energy and heat by conduction a solvent more or less transparent to microwaves.
- This mstai-ation comprises a container 1001 in the form of a balloon containing an extraction solvent heated by conventional heating means 1002.
- conventional cnauffage means means an electric or gas heating plate for example.
- This installation 1000 further comprises means 1003 for emitting microwaves, for example a magnetron, in a cavity 1100 for applying microwaves.
- This application cavity 1100 is delimited by an upper wall 1110, a cylindrical side wall 1120 and a lower wall 1130.
- the upper wall 1110 of said cavity 1100 is provided with an opening 1111 which is bordered by a chimney 1112 whose height H depends on the section of the opening 1111 and on the frequency of emission of microwaves in said cavity , is such that said chimney forms a barrier to the propagation of microwaves out of the cavity.
- This opening 1111 allows the introduction into said application cavity 1100 of a flask 1 coupled to an extraction device 100 according to the invention.
- this extraction device 100 is that shown more particularly in FIGS. 2a to 2c.
- the lower part 1130 of said microwave application cavity 1100 includes an orifice 1131 also bordered by a chimney 1132 whose height H which is a function of the frequency of emission of the microwaves and of the section of the orifice 1131, is such that said chimney forms a barrier to the propagation of microwaves towards the outside of the cavity.
- the orifice 1131 allows the passage of a first external tube 1004 which connects the bottom of the flask 1 to said container 1001 containing the solvent.
- this first outer tubu_ re 1004 has the shape of a siphon.
- This second external tube fits on the valve 142 of the reservoir 140 and opens into the interior of the solvent container 1001.
- the operating mode of this installation is as follows.
- the solvent in the solvent container 1001 is heated, which evaporates and circulates in the second connection tube 1005 to reach the reservoir 140 where it recondenses when it comes into contact. refrigerant 144.
- the solvent in this flask vaporizes again and is recondensed in the reservoir 140 before flowing through the connection duct 150 and the rod 110 in the bottom of the flask 1 while crossing the cartridge 120.
- the part of the solvent loaded with extracted compounds which does not vaporize flows from the bottom of the flask 1 to the first connection tubing 1004 until the level in this tubing rises.
- the level of the solvent in the tubing increases until it reaches the elbow of the siphon and then falls back into the solvent container 1001.
- the extraction is carried out by means of a vaporized solvent, recon ⁇ ensed then revaporized and recondensed.
- Two sources of heat are used, a traditional source and a source of heat under microwaves, to carry out the extraction.
- Heating the microwave solvent that passes through the cartridge increases the speed of extraction of comDosés. Thanks to this installation, it is possible to better control the extraction operation by varying the traditional heating, the microwave heating and the solvent used. For a given microwave power, by choosing a solvent more or less transparent to microwaves, it is possible to more or less heat said solvent during its passage through the microwave cavity and by this means, vary the time and quality of extraction of the sample placed in the cartridge.
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002256032A CA2256032A1 (en) | 1996-05-20 | 1997-05-20 | Device and installation for microwave extracting of organic compounds from a sample |
EP97925106A EP0907394A1 (en) | 1996-05-20 | 1997-05-20 | Device and installation for microwave extracting of organic compounds from a sample |
JP09541714A JP2000510765A (en) | 1996-05-20 | 1997-05-20 | Apparatus and equipment for extracting organic compounds from samples by adding microwaves |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1904096P | 1996-05-20 | 1996-05-20 | |
US60/019,040 | 1996-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997044109A1 true WO1997044109A1 (en) | 1997-11-27 |
Family
ID=21791115
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR1997/000883 WO1997044109A1 (en) | 1996-05-20 | 1997-05-20 | Device and installation for microwave extracting of organic compounds from a sample |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0907394A1 (en) |
JP (1) | JP2000510765A (en) |
KR (1) | KR20000015867A (en) |
CA (1) | CA2256032A1 (en) |
WO (1) | WO1997044109A1 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2212748A1 (en) * | 2003-01-14 | 2004-07-16 | Universidad De Cordoba | Device for the microwave-accelerated extraction of components of solid samples and applications thereof |
EP1593952A1 (en) * | 2004-05-05 | 2005-11-09 | C. Gerhardt Fabrik und Lager chemischer Apparate GmbH & Co. KG | Apparatus and method for discontinuous hydrolysis |
WO2008089937A2 (en) * | 2007-01-22 | 2008-07-31 | Milestone S.R.L. | Microwave integrated soxhlet |
WO2008089943A1 (en) * | 2007-01-22 | 2008-07-31 | Milestone S.R.L. | Microwave hydrodiffusion for isolation of natural products |
WO2019106313A1 (en) * | 2017-12-01 | 2019-06-06 | Université D'avignon Et Des Pays De Vaucluse | Device for extracting and separating volatile and non-volatile compounds from a biological material, and associated process |
US20210284928A1 (en) * | 2016-12-01 | 2021-09-16 | Natural Extraction Systems, LLC | Rapid botanical oil distillation device utilizing microwave agent |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100556354B1 (en) * | 2002-09-30 | 2006-03-03 | 엘지전자 주식회사 | refining method for organic matter |
JP2007289916A (en) * | 2006-03-31 | 2007-11-08 | Tokyo Electric Power Co Inc:The | Small extractor |
JP4831044B2 (en) * | 2007-03-30 | 2011-12-07 | 東京電力株式会社 | Small extractor for microwave oven |
CN101290277B (en) * | 2007-04-20 | 2011-05-11 | 财团法人食品工业发展研究所 | Rapid extraction method utilizing microwave radiation |
TW200842336A (en) * | 2007-04-26 | 2008-11-01 | Food Industry Res & Dev Inst | Microwave accelerating extraction equipment |
KR100817536B1 (en) * | 2007-10-31 | 2008-03-27 | (주)제네마인 | A high performance extractor as possible with ascending and descending extraction |
JP4831060B2 (en) * | 2007-12-19 | 2011-12-07 | 東京電力株式会社 | Small extractor for microwave oven |
WO2014121814A1 (en) * | 2013-02-05 | 2014-08-14 | Foss Analytical Ab | Solvent extraction apparatus |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3397115A (en) * | 1967-08-07 | 1968-08-13 | Dow Chemical Co | Extraction apparatus |
FR2252861A1 (en) * | 1973-12-04 | 1975-06-27 | Randall Edward | Liq and vapour solvent extraction - performed in a single vessel in which the sample container can be positioned above and below solvent surface |
US4255386A (en) * | 1978-11-30 | 1981-03-10 | The United States Of America As Represented By The Deptartment Of Health, Education And Welfare | Method and apparatus for destroying organic matter to facilitate trace inorganic element analysis |
US4265860A (en) * | 1980-03-27 | 1981-05-05 | J & W Scientific, Incorporated | High pressure Soxhlet extractor |
-
1997
- 1997-05-20 KR KR1019980709417A patent/KR20000015867A/en not_active Application Discontinuation
- 1997-05-20 WO PCT/FR1997/000883 patent/WO1997044109A1/en not_active Application Discontinuation
- 1997-05-20 EP EP97925106A patent/EP0907394A1/en not_active Ceased
- 1997-05-20 JP JP09541714A patent/JP2000510765A/en active Pending
- 1997-05-20 CA CA002256032A patent/CA2256032A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3397115A (en) * | 1967-08-07 | 1968-08-13 | Dow Chemical Co | Extraction apparatus |
FR2252861A1 (en) * | 1973-12-04 | 1975-06-27 | Randall Edward | Liq and vapour solvent extraction - performed in a single vessel in which the sample container can be positioned above and below solvent surface |
US4255386A (en) * | 1978-11-30 | 1981-03-10 | The United States Of America As Represented By The Deptartment Of Health, Education And Welfare | Method and apparatus for destroying organic matter to facilitate trace inorganic element analysis |
US4265860A (en) * | 1980-03-27 | 1981-05-05 | J & W Scientific, Incorporated | High pressure Soxhlet extractor |
Non-Patent Citations (1)
Title |
---|
"Microwave heating accelerates solvent extraction", CHEMICAL ENGINEERING, vol. 102, no. 2, 1 February 1995 (1995-02-01), pages 13, XP000489694 * |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2212748A1 (en) * | 2003-01-14 | 2004-07-16 | Universidad De Cordoba | Device for the microwave-accelerated extraction of components of solid samples and applications thereof |
WO2004062766A1 (en) * | 2003-01-14 | 2004-07-29 | Universidad de Córdoba | Device for the microwave-accelerated extraction of components of solid samples and applications thereof |
EP1593952A1 (en) * | 2004-05-05 | 2005-11-09 | C. Gerhardt Fabrik und Lager chemischer Apparate GmbH & Co. KG | Apparatus and method for discontinuous hydrolysis |
WO2008089937A2 (en) * | 2007-01-22 | 2008-07-31 | Milestone S.R.L. | Microwave integrated soxhlet |
WO2008089943A1 (en) * | 2007-01-22 | 2008-07-31 | Milestone S.R.L. | Microwave hydrodiffusion for isolation of natural products |
EP1955749A1 (en) * | 2007-01-22 | 2008-08-13 | Milestone S.r.l. | Microwave hydrodiffusion for isolation of natural products |
EP1955748A1 (en) * | 2007-01-22 | 2008-08-13 | Milestone S.r.l. | Microwave integrated soxhlet |
WO2008089937A3 (en) * | 2007-01-22 | 2008-09-18 | Milestone Srl | Microwave integrated soxhlet |
US8802021B2 (en) | 2007-01-22 | 2014-08-12 | Milestone S.R.L. | Microwave integrated Soxhlet |
US20210284928A1 (en) * | 2016-12-01 | 2021-09-16 | Natural Extraction Systems, LLC | Rapid botanical oil distillation device utilizing microwave agent |
US11820959B2 (en) * | 2016-12-01 | 2023-11-21 | Natural Extraction Systems, LLC | Rapid botanical oil distillation device utilizing microwave agent |
WO2019106313A1 (en) * | 2017-12-01 | 2019-06-06 | Université D'avignon Et Des Pays De Vaucluse | Device for extracting and separating volatile and non-volatile compounds from a biological material, and associated process |
Also Published As
Publication number | Publication date |
---|---|
JP2000510765A (en) | 2000-08-22 |
CA2256032A1 (en) | 1997-11-27 |
EP0907394A1 (en) | 1999-04-14 |
KR20000015867A (en) | 2000-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1997044109A1 (en) | Device and installation for microwave extracting of organic compounds from a sample | |
CA2019416C (en) | Centrifugal separator for congealable liquid, gas-oil for example | |
EP0180528A2 (en) | Method for the medical analysis of a liquid sample by means of at least one liquid reagent, and apparatus for carrying out the method | |
WO1998057896A1 (en) | Installation for producing ozonized water | |
EP0739483B1 (en) | Device for automatically injecting solubilized or diluted products | |
EP0045247B1 (en) | Apparatus for the automatic preparation of samples for analysing | |
EP2983884A1 (en) | Device for treating a solid composite material by solvolysis with a view to extracting fibres from the treated material | |
EP1144321B1 (en) | Method and device for drawing a molten material contained in a crucible | |
EP3592145A1 (en) | System and method for vitrifying a biological substance | |
BE897901A (en) | APPARATUS AND METHOD FOR DEGASSING A LIQUID, PARTICULARLY WATER | |
CA1251340A (en) | Device suitable e.g. for small solid of liquid sample pyrolysis | |
FR3029629A1 (en) | METHOD AND DEVICE FOR SAMPLING SAMPLE IN A LIQUID | |
EP0017588B1 (en) | Electromagnetic device for the separation of inclusions contained in an electrically conductive fluid | |
FR2709250A1 (en) | Device for selecting spermatozoa | |
FR2570956A1 (en) | Process and device allowing two substances to be separated by dissolving | |
FR2533898A1 (en) | Device for the automatic emptying of a container | |
FR2980262B1 (en) | METHOD OF FREEZING A PLURALITY OF PACKAGING TUBES FILLED EACH OF A PREDETERMINED VOLUME OF BIOLOGICAL SUBSTANCE AND SYSTEM FOR IMPLEMENTING SUCH A METHOD | |
EP0608153A1 (en) | Reaction apparatus with automatic dosing system, especially for DNA extraction | |
FR2691080A1 (en) | Superconducting magnetic separator and process for clarifying liquids - used in partic. for removing fine particles from reprocessing liquids, resulting from reprocessing of used nuclear fuel | |
FR2481325A1 (en) | NACELLE USABLE FOR LIQUID-LIQUID MULTILAYER EPITAXIC DEPOSITS AND METHOD OF DEPOSITION INVOLVING SAID NACELLE | |
WO2005002708A1 (en) | Device for the separation of particles contained in a fluid stream and cleaning installation comprising one such separation device | |
EP4170316A1 (en) | Sample collection apparatus and sample collection device | |
BE516709A (en) | ||
FR2601444A1 (en) | Closure for a receptacle fitted with a metering device | |
FR2545202A1 (en) | METHOD AND DEVICE FOR COOLING A MATERIAL AND APPLICATION TO THE PRODUCTION OF REFRACTORY MATERIALS BY TEMPERATURE |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 97195615.4 Country of ref document: CN |
|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): CA CN JP KR US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2256032 Country of ref document: CA Ref document number: 2256032 Country of ref document: CA Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1019980709417 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1997925106 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1997925106 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1019980709417 Country of ref document: KR |
|
WWR | Wipo information: refused in national office |
Ref document number: 1997925106 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1997925106 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1019980709417 Country of ref document: KR |