WO1997043967A1 - Electrosurgical instrument and method of use - Google Patents
Electrosurgical instrument and method of use Download PDFInfo
- Publication number
- WO1997043967A1 WO1997043967A1 PCT/US1997/008313 US9708313W WO9743967A1 WO 1997043967 A1 WO1997043967 A1 WO 1997043967A1 US 9708313 W US9708313 W US 9708313W WO 9743967 A1 WO9743967 A1 WO 9743967A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- electrode
- instrument
- cutting
- coagulating
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/149—Probes or electrodes therefor bow shaped or with rotatable body at cantilever end, e.g. for resectoscopes, or coagulating rollers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00589—Coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00601—Cutting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00607—Coagulation and cutting with the same instrument
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/1246—Generators therefor characterised by the output polarity
- A61B2018/1253—Generators therefor characterised by the output polarity monopolar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/1246—Generators therefor characterised by the output polarity
- A61B2018/126—Generators therefor characterised by the output polarity bipolar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/1273—Generators therefor including multiple generators in one device
Definitions
- This invention relates in general to a surgical instrument, and in particular to an electrosurgical instrument that sequentially cuts or resects and coagulates tissue with one movement of the instrument through the tissue.
- a cutting electrode of a first instrument is provided with sufficient current to cut through tissue by vaporizing cellular structure in the surgical path of the electrode.
- a coagulation electrode of a second instrument and with a lesser magnitude of current is introduced to the surgical path to thereby coagulate transected bleeding blood vessels by desiccation, shrinkage of surrounding tissue, and/or fusion of vessel walls.
- Typical prior art electrosurgical devices include a scissor-type forceps-style instrument, a ⁇ described in U.S. Patent No. 2,011,169 to Wappler; a double-loop cutting device having a proximal cutting loop connected to a live pole and a distal loop connected to a neutral pole, as described in U.S. Patent No. 4,060,087 to Hiltebrandt et al.; a single-loop surgical snare device having two electrodes for providing bipolar cauterization, as described in U.S. Patent No. 5,318,564 to Korth et al.
- a proximal cutting loop is un-insulated and a distal insulated support loop having no power supply functions to support and guide the proximal cutting loop, as described in U.S. Patent No. 5,318,564 to Eggers.
- Double loop devices having identical power amplitudes to each loop are available for singular cutting or singular coagulating activity.
- a primary object of the present invention is to provide an electrosurgical instrument capable of sequentially cutting and coagulating tissue with a single movement of the instrument through tissue.
- Another object of the present invention is to provide an electrosurgical instrument with a cutting electrode having a first current magnitude appropriate for cutting tissue, and a coagulation electrode having a second current magnitude appropriate for coagulating tissue.
- Another object of the present invention is to provide an electrosurgical instrument having a cutting electrode and coagulation electrode which are formed having differing cross-sectional configurations specifically adapted to allow the coagulation electrode to follow a cutting electrode and thereby promote rapid coagulation of the tissue.
- Another object of the present invention is to provide an electrosurgical instrument with a cutting electrode having a first current magnitude appropriate for cutting tissue, and a coagulation electrode having a second current magnitude appropriate for coagulating tissue.
- the present invention discloses an electrosurgical instrument for sequentially cutting and coagulating tissue, and includes methodology for electrosurgical procedures incorporating principles of the inventive instrument.
- the instrument comprises a cutting electrode connectable to a first power source having a first power amplitude or signal sufficient to cut tissue, and a coagulating electrode connectable to a second power source having a second power amplitude sufficient to coagulate and not cut tissue.
- the electrodes each have respective distal ends maintained in a spaced relationship to each other such that the distal end of the coagulating electrode can immediately follow the distal end of the cutting electrode during movement of the instrument, thereby providing substantially simultaneous cutting and coagulating of affected tissue.
- Non-limiting paired-configurations of respective distal ends include loops, hooks, scalpel-blade shaped members, paddles, and any other configurations that beneficially accomplish resection of tissue and subsequent coagulation.
- Dimensions and/or cross-sectional configurations of paired electrodes can be different from each other to thereby enhance as desired an electrosurgical function. Thus, for example, increasing the size of a coagulating electrode will result in greater surface area being in contact with tissue which results in greater coagulation activity.
- Methodology for performing an electrosurgical procedure in tissue comprises providing the above described instrument with energy delivery to the electrodes.
- the power amplitude or signal to the cutting electrode is preferably greater than that supplied to the coagulation electrode in accord with required respective amplitudes to accomplish cutting and coagulation.
- the charged instrument is then introduced to the tissue to be cut and moved therethrough with a single stroke that effectuates tissue cutting and coagulation.
- Figure 1 is a perspective view of an electrosurgical instrument having uniformly-shaped semi-circular loop electrodes for tissue resection;
- Figure 2 is a perspective view of the instrument of Figure 1 in tissue
- Figure 3 is a perspective view of a second embodiment of an electrosurgical instrument having hook- shaped electrodes
- Figure 4 is a perspective view of a third embodiment of double loop construction similar to Figure 1 except with a separator membrane;
- Figure 5 is a perspective view of a forward portion of a fourth embodiment of an electrosurgical instrument having generally scalpel-blade shaped electrodes
- Figure 6 is a perspective view of a fifth embodiment of an electrosurgical instrument wherein the cutting electrode and coagulation electrode are separated by an electrical insulator and the electrodes and electrical insulator are maintained in a contiguous, generally integral configuration so as to promote ease and manipulation of the instrument through tissue;
- Figure 7 is a cross-sectional view taken about lines 7-7 of Figure 6;
- Figure 8 is a perspective view of a sixth embodiment of an electrosurgical instrument wherein the cutting electrode and coagulation electrode are specifically formed having differing cross-sectional configurations to allow the coagulation electrode to follow and contact the tissue during resection;
- Figure 9 is a cross-sectional view taken about lines 9-9 of Figure 8; and Figure 10 is a perspective view of the electrosurgical instrument of Figure 8 in tissue being utilized with a dispersive electrode positioned in dwelling within the patient adjacent to or residing within the surgical site.
- each electrode 12, 14 is an electrically conductive metal wire, preferably formed of stainless steel, having electrical insulation 16 along its length except for non-insulated distal uniformly- shaped semi-circular loops 18, 20 employed in surgical procedures.
- the non-insulated loops 18, 20 are preferably positioned or spaced from one another to prevent any electrical arcing within the tissue. Should the non-insulated loops 18, 20 arc while in tissue, the loops 18, 20 may be operative to provide only coagulation, thereby safely preventing any cutting action without subsequent coagulation action.
- the electrodes 12, 14 are connectable through a non-conducting handle member 23 to preferably two separate standard electrical energy sources 22a, 22b capable of delivering different selectable power or signal values simultaneously to the two electrodes 12, 14.
- the loop 18 of the cutting electrode 12 is positioned proximally from the loop 20 of the coagulation electrode 14, but such designation is determined solely by the amplitude of power being delivered to the respective electrodes 12, 14 since illustrated electrode-construction is identical.
- the instrument 10 can be moved in a forward or rearward direction by simply reversing current magnitude delivered to the electrodes 12, 14. Movement, of course, must be such that the loop of the coagulation electrode follows the loop of the cutting electrode in substantially the same pathway.
- the electrodes can differ from each other, with, for example, a distal coagulating electrode loop being broader to thereby contact tissue for a longer period of time.
- the distal electrode can be constructed of spring steel. This construction assures that, after the proximal cutting electrode makes site contact, the distal coagulating electrode also follows with substantially the same site contact to thereby effectuate coagulation immediately after cutting. Referring to Figure 2, the loop 18 of the cutting electrode 12 is shown performing a tissue resection of portion 24 from a tissue base 26 by moving the instrument 10 in the direction of the arrow.
- the loop 18 of the cutting electrode 12 first cuts cells originally situated between the tissue portion 24 and tissue base 26, and the loop 20 of the coagulation electrode 14 sequentially substantially immediately thereafter coagulates the transected blood vessels in the tissue base 26 to thereby cause coagulation.
- the power amplitude or signal delivered to the cutting electrode 12 is preferably between about 150 and about 300 watts, while power amplitude delivered to the coagulation electrode 14 is preferably between about 80 and about 140 watts.
- Figure 3 illustrates a second embodiment of an electrosurgical instrument 27 wherein a cutting electrode 28 and coagulation electrode 30 are hook-shaped for use where such a configuration is beneficial.
- each electrode 28, 30 is constructed of an electrically conductive metal wire having electrical insulation 16 along its length except for the non-insulated distal hooks 32, 34 employed in surgical procedures. As with the non-insulated loops 18, 20 of the instrument 10, should the non-insulated hooks 32, 34 arc while in tissue, the hooks 32, 34 may be operative to only provide coagulation, thereby safely preventing any cutting action without subsequent coagulation action.
- the electrodes 28, 30 are connectable through a non-conductive handle member 31 to two separate standard electrical energy sources 22a, 22b capable of delivering different selectable power values simultaneously to the two electrodes 28, 30.
- the hook 32 of the cutting electrode 28 is positioned proximally from the hook 34 of the coagulation electrode 30, but such designation is determined solely by the magnitude of current being delivered to the respective electrodes 12, 14 since electrode construction is identical.
- the instrument 27 can be moved in a forward or rearward direction by simply reversing current magnitude delivered to the electrodes 28, 30. Movement, of course, must be such that the hook of the coagulation electrode follows the hook of the cutting electrode in substantially the same pathway.
- the electrodes can differ from each other, with, for example, a distal coagulating electrode hook being broader to thereby contact tissue for a longer period of time.
- the distal electrode can be constructed of spring steel so that its tissue contact path is substantially the same as that of the proximal cutting electrode and coagulation immediately follows cutting. Power amplitudes for cutting and for coagulation are substantially similar to those recited above for the instrument 10.
- the patient functions as ground, or a third pole at the site functions as ground with use of this embodiment.
- a double-loop cutting portion embodiment shown in Figure 4 is similar to the instrument 10 of Figure 1, except that a flexible, semi-rigid or rigid membrane 36 formed of an electrically insulated material is disposed between the electrode loops 18, 20 to thereby avoid tissue becoming lodged between these loops and to prevent arcing.
- Figure 5 illustrates a two-element cutting portion embodiment 40 comprising two tandem members 42, 44 wherein the first member 42 is shorter and functions as a cutting electrode, while the second member 44 is longer to thereby follow the first member 42 and functions as a coagulating electrode.
- the two members together resemble a single scalpel blade split and spaced along a central vertical axis. While the members 42, 44 are scalpel- blade shaped, they do not need to be sharp. Thus, for example, the cutting member can be sharp or dull, while the coagulating member is dull.
- the members 42, 44 project from an insulated handle member 46 in substantially the same manner as the electrodes of the embodiment of Figure 1, and each is connected to a separate power source (not shown) as in the embodiments of Figures 1 and 3.
- the members 42 and 44 are spaced from one another to prevent arcing and/or may be provided with electrical insulation to prevent arcing between themselves in tissue. Power amplitude to the cutting first member 42 is greater than that to the coagulating second member 44, with respective values being substantially the same as defined for the embodiment of Figure 1.
- the patient functions as ground, or a third pole or dispersive electrode (not shown) at the site functions as ground with use of this embodiment.
- members 42, 44 may be operative to provide coagulation, thereby safely preventing any cutting action without subsequent coagulation action.
- a surgeon connects an embodiment to respective power sources such that the cutting electrode thereof has sufficient power signal to cut tissue while the coagulating electrode thereof has sufficient power to coagulate and not cut tissue. Thereafter, the electrodes are introduced to and drawn through tissue to be cut such that the coagulating electrode immediately follows the cutting electrode.
- FIG. 6 an additional embodiment of the electrosurgical instrument of the present invention is depicted wherein the cutting electrode and coagulation electrode are separated by an electrical insulator and formed in a contiguous orientation to approximate the feel of a conventional prior art single wire loop electrosurgical instrument. More particularly, as shown in Figure 6, the cutting electrode 50 and coagulation electrode 52 are both formed in an arcuate wire loop configuration and are separated by an electrical insulator 54. As best shown in Figure 7, the electrical insulator 54 is formed having an hourglass-like configuration and is permanently affixed to both cutting electrode 50 and coagulation electrode 52.
- Each of the electrodes 50 and 52 are electrically connected by insulated conductors 56 and 58 which extend through the hand piece or handle 60 and are each connected to a respective pair of power sources 22a and 22b (shown in Figure 1).
- actuation of the power sources 22a and 22b cause differing electrosurgical power signals to be supplied to the cutting electrode 50 and coagulation electrode 52.
- the electrosurgical instrument closely approximates the configuration and tactile feel of a conventional single-loop electrosurgical instrument as that currently utilized in the art.
- the surgeon may easily manipulate the electrosurgical instrument in a manner substantially identical to that previously utilized while performing a cutting as well as coagulation function in a single movement through tissue.
- the surgeon may pivot or rotate the electrosurgical instrument after cutting and subsequently move the instrument backward over the cut tissue with only the coagulation electrode contacting the tissue to insure that desired coagulation is being achieved upon the tissue.
- an additional embodiment of the electrosurgical instrument of the present invention is disclosed which is similar to the embodiment of Figure 6 but includes differing shaped cutting and coagulation electrodes specifically adapted to promote cutting and coagulation functions.
- the cutting electrode 70 and coagulation electrode 72 are additionally preferably formed in an arcuate wire loop configuration separated by an electrical insulator 74.
- the cutting electrode 70 and coagulation electrode 72 are formed having differing cross-sectional configurations specifically adapted to promote cutting and coagulation of tissue.
- the cutting electrode 70 preferably is formed having a smaller cross-sectional configuration then the coagulation electrode 72. Additionally, the leading edge of the cutting electrode 70 is preferably formed having a smaller radius 76 then the trailing edge radius 78 of the coagulation electrode. As in the previous embodiments, insulated conductors 80 and 82 serve to electrically interface the electrodes 70 and 72 to a pair of energy or power sources 22a and 22b (shown in Figure 1) through the handle member 90.
- the cutting electrode 70 and coagulation electrode 72 are preferably vertically offset from one another which, in combination with their differing cross-sectional configurations, serves to promote a proper following or tracking of the coagulation electrode 72 relative the cutting electrode 70 through tissue (i.e., the particular configuration and offset spacing of the electrodes 70 and 72 promotes proper contact of the coagulation electrode 72 with the tissue after cutting). Further, due to the surface area of the coagulation electrode 72 be greater than the surface area of the cutting electrode 70, the tissue is contacted for a greater time duration to promote proper coagulation. Additionally, by pivoting or rotating the electrosurgical instrument during tissue resection in a counterclockwise direction as depicted by the arrow in Figure 9, it will be recognized that the coagulation electrode 72 will be pressed downwardly against the cut tissue to promote coagulation.
- the electrosurgical instrument of Figure 8 is depicted in use in a tissue cutting application.
- the electrosurgical instrument can be utilized with a conventional dispersive electrode(s) (not shown) which is applied to the patient's body at a site away from the surgical field
- the present invention additionally contemplates the use of an in-dwelling dispersive electrode 100 which may be inserted into the patient's body 102 to reside within or adjacent the surgical site 104.
- the in-dwelling electrode 100 comprises one or more hypodermic needles or stylets having an electrically conductive distal end 110 and an electrically insulated sleeve 112.
- the proximal end of the hypodermic needle 100 may be connected via conventional conductors (not shown) to the electrosurgical generator or power source 22a and 22b (shown in Figure 1). Further, it is contemplated that a electrically conductive fluid, such as a hypertonic saline solution, may be injected through the needle 100 to reside in the tissue surrounding the operative site.
- electrosurgical power is dispersed from the electrosurgical instrument through the surgical site 104 into the saline solution and into in ⁇ dwelling dispersive electrode 100.
- the in-dwelling dispersive electrode 100 Due to the close proximity of the in-dwelling dispersive electrode 100 to the surgical site 104, electrosurgery results from the concentration of electrical energy in the surgical site 104 such that the local tissue is cut and/or coagulated. Further, due to the saline solution forming an enlarged and greater electrically conductive area or volume within the patient, cutting or burning of tissue adjacent to the operative site and proximal the needle 100 is minimized, and a preferential electrical path from the electrodes 70 and 72 to the dispersive electrode needle 100 is facilitated.
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Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97924740A EP0904024A4 (en) | 1996-05-21 | 1997-05-15 | Electrosurgical instrument and method of use |
JP09542570A JP2000511077A (en) | 1996-05-21 | 1997-05-15 | Electrosurgical instrument and method of using the same |
CA002254921A CA2254921A1 (en) | 1996-05-21 | 1997-05-15 | Electrosurgical instrument and method of use |
AU30081/97A AU3008197A (en) | 1996-05-21 | 1997-05-15 | Electrosurgical instrument and method of use |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65189296A | 1996-05-21 | 1996-05-21 | |
US08/651,892 | 1996-05-21 |
Publications (1)
Publication Number | Publication Date |
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WO1997043967A1 true WO1997043967A1 (en) | 1997-11-27 |
Family
ID=24614664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/008313 WO1997043967A1 (en) | 1996-05-21 | 1997-05-15 | Electrosurgical instrument and method of use |
Country Status (6)
Country | Link |
---|---|
US (2) | US5919189A (en) |
EP (1) | EP0904024A4 (en) |
JP (1) | JP2000511077A (en) |
AU (1) | AU3008197A (en) |
CA (1) | CA2254921A1 (en) |
WO (1) | WO1997043967A1 (en) |
Cited By (6)
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WO1998038932A1 (en) * | 1997-03-07 | 1998-09-11 | Advanced Closure Systems, Inc. | Resectoscope electrode assembly with simultaneous cutting and coagulation |
US5993445A (en) * | 1995-05-22 | 1999-11-30 | Advanced Closure Systems, Inc. | Resectoscope electrode assembly with simultaneous cutting and coagulation |
EP0966232A1 (en) * | 1996-12-20 | 1999-12-29 | Gregg A. Vandusseldorp | Cutting loop for an electrocautery probe |
EP1011497A1 (en) * | 1997-03-31 | 2000-06-28 | Ethicon, Inc. | Serpentine ablation/coagulation electrode |
US7108695B2 (en) * | 1999-05-26 | 2006-09-19 | Ethicon Endo-Surgery, Inc. | Feedback control in an ultrasonic surgical instrument for improved tissue effects |
US10765471B2 (en) | 2016-04-15 | 2020-09-08 | Bolder Surgical, Llc | Electrosurgical sealer and divider |
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US5697882A (en) * | 1992-01-07 | 1997-12-16 | Arthrocare Corporation | System and method for electrosurgical cutting and ablation |
US6159194A (en) * | 1992-01-07 | 2000-12-12 | Arthrocare Corporation | System and method for electrosurgical tissue contraction |
US6682501B1 (en) * | 1996-02-23 | 2004-01-27 | Gyrus Ent, L.L.C. | Submucosal tonsillectomy apparatus and method |
US6620155B2 (en) | 1996-07-16 | 2003-09-16 | Arthrocare Corp. | System and methods for electrosurgical tissue contraction within the spine |
US7276063B2 (en) * | 1998-08-11 | 2007-10-02 | Arthrocare Corporation | Instrument for electrosurgical tissue treatment |
US6325801B1 (en) * | 1999-12-04 | 2001-12-04 | Karl Storz Gmbh & Co. Kg | Instrument for severing tissue with HF current |
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US6808525B2 (en) | 2001-08-27 | 2004-10-26 | Gyrus Medical, Inc. | Bipolar electrosurgical hook probe for cutting and coagulating tissue |
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US8043286B2 (en) | 2002-05-03 | 2011-10-25 | The Board Of Trustees Of The Leland Stanford Junior University | Method and apparatus for plasma-mediated thermo-electrical ablation |
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Also Published As
Publication number | Publication date |
---|---|
US6030383A (en) | 2000-02-29 |
CA2254921A1 (en) | 1997-11-27 |
AU3008197A (en) | 1997-12-09 |
US5919189A (en) | 1999-07-06 |
EP0904024A1 (en) | 1999-03-31 |
JP2000511077A (en) | 2000-08-29 |
EP0904024A4 (en) | 2000-04-19 |
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