Classifications

• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D53/00—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
  • B01D53/02—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography
  • B01D53/04—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K33/00—Medicinal preparations containing inorganic active ingredients
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
  • A61M16/10—Preparation of respiratory gases or vapours
  • A61M16/105—Filters
  • A61M16/106—Filters in a path
  • A61M16/107—Filters in a path in the inspiratory path
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
  • A61M16/10—Preparation of respiratory gases or vapours
  • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M2202/00—Special media to be introduced, removed or treated
  • A61M2202/02—Gases
  • A61M2202/0266—Nitrogen (N)
  • A61M2202/0275—Nitric oxide [NO]
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D2253/00—Adsorbents used in seperation treatment of gases and vapours
  • B01D2253/10—Inorganic adsorbents
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D2253/00—Adsorbents used in seperation treatment of gases and vapours
  • B01D2253/20—Organic adsorbents
  • B01D2253/202—Polymeric adsorbents
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D2257/00—Components to be removed
  • B01D2257/40—Nitrogen compounds
  • B01D2257/404—Nitrogen oxides other than dinitrogen oxide
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01D—SEPARATION
  • B01D2259/00—Type of treatment
  • B01D2259/45—Gas separation or purification devices adapted for specific applications
  • B01D2259/4533—Gas separation or purification devices adapted for specific applications for medical purposes

Definitions

• the invention relates to a method for reducing risks in inhalative NO therapy according to the preamble of claim 1 and to a device suitable for carrying out the method.
• NO nitrogen monoxide
• NO 2 nitrogen dioxide
• N0 2 nitrite
• NO 3 nitrate
• a gas mixture containing NO can either be added directly in the respirator or in the inspiratory leg of the hose system.
• the patient thus receives the breathing gas together with the NO-containing gas mixture.
• the inevitable presence of oxygen and water (moisture) leads to the formation of NO 2 and N0 2 " .
• NO can be administered to the patient using simple breaths such as breathing masks or nasal cannulae in oxygen or oxygen mixtures with air and / or noble gases such as helium. Both here and in respiratory weaning therapies, NO showed a significant improvement in health.
• NO-N 2 or NO-He or also NO-noble gas mixtures are added to the spontaneous breather either in batches (in the rhythm of breathing) or continuously to the "auxiliary breathing volume flow".
• longer oxidation times lead to higher oxidation rates, ie to an increased production of toxic NO 2 .
• HNO 2 nitrous acid
• HN0 3 nitric acid
• the invention has for its object to provide a method for inhalative NO therapy, which ensures a homogeneous mixing of the gas streams used and preferably at the same time allows removal of the gaseous impurities NO2, N 2 O 3 and N 2 O 4 .
• a filter is preferably used which is filled with a filter or absorber mass which is capable of selectively absorbing NO 2 from gas mixtures containing NO.
• a filter or absorber mass which is capable of selectively absorbing NO 2 from gas mixtures containing NO.
• This can be a sulfur-containing polymer, as described in DE 44 19 860 A1.
• a particular advantage of such a filter is that it simultaneously prevents the formation of N0 2 ' (nitrite) and N0 3 " (nitrate) in the condensate and any anions that may have formed can be removed.
• the NO-conducting line part can also be used as a support also contain a sulfur-containing polymer
• the filter material can consist, for example, of a granulate or fleece.
• Figure 1 possible filter arrangements in connection with a
• Respirator Figure 2: possible filter arrangements for spontaneous breathing.
• the device shown in FIG. 1 contains a respirator 1 with a connection piece 2 for the supply of oxygen, a connection piece 3 for the supply of air and an exhaust air connection 4.
• a patient 7 is connected to the respirator 1 via a line 5 with a humidifier 6 .
• a line 8 for the exhaled gas leads from a point near the patient 7 from line 5 back into the respirator.
• Another component of the device is an NO metering device 9, which is connected via a line 10 to a bottle 11 with a gas mixture containing NO. NO is metered into line 5 through line 12, and the analysis is withdrawn via line 13.
• a filter with a sulfur-containing polymer as an effective component is arranged in the NO-conducting line part.
• Possible filter arrangements are labeled A, B1, B2, C1, C2 and C3.
• the lines 14, 15 and 16 shown in dashed lines show further possibilities for the NO supply, which may also be provided with filters effective according to the invention.
• Figure 2 shows a device with possible filter arrangements for spontaneous breathing.
• the NO-containing gas mixture is in the store 17, in the store 18 there is noble gas, in the store 19 air and in the store 20 oxygen.
• a breathing gas is formed from noble gas, air and oxygen, to which the NO-containing gas mixture is admixed.
• the entire mixture passes through line 21 to the humidifier 97/36627 PC17EP97 / 01565
• Filterpositione ⁇ effective according to the invention are denoted by D1, D2 and.

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• Health & Medical Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• Public Health (AREA)
• Life Sciences & Earth Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Engineering & Computer Science (AREA)
• General Health & Medical Sciences (AREA)
• Veterinary Medicine (AREA)
• Hematology (AREA)
• Heart & Thoracic Surgery (AREA)
• Biomedical Technology (AREA)
• Anesthesiology (AREA)
• Pulmonology (AREA)
• Emergency Medicine (AREA)
• Inorganic Chemistry (AREA)
• Epidemiology (AREA)
• General Chemical & Material Sciences (AREA)
• Pharmacology & Pharmacy (AREA)
• Medicinal Chemistry (AREA)
• Analytical Chemistry (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Oil, Petroleum & Natural Gas (AREA)
• Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
• Respiratory Apparatuses And Protective Means (AREA)

Applications Claiming Priority (2)

Publications (1)

Family

ID=7789692

Family Applications (1)

Country Status (3)

Cited By (1)

Families Citing this family (6)

Citations (4)

• 1996
  • 1996-03-28 DE DE19612289A patent/DE19612289A1/de not_active Withdrawn
• 1997
  • 1997-03-27 ZA ZA9702728A patent/ZA972728B/xx unknown
  • 1997-03-27 WO PCT/EP1997/001565 patent/WO1997036627A1/de active Application Filing

Patent Citations (4)

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