WO1997007139A3 - Stabilized chitin derivative compounds - Google Patents

Stabilized chitin derivative compounds Download PDF

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Publication number
WO1997007139A3
WO1997007139A3 PCT/EP1996/003474 EP9603474W WO9707139A3 WO 1997007139 A3 WO1997007139 A3 WO 1997007139A3 EP 9603474 W EP9603474 W EP 9603474W WO 9707139 A3 WO9707139 A3 WO 9707139A3
Authority
WO
WIPO (PCT)
Prior art keywords
polysaccharide
stabilized
chitin derivative
derivative compounds
solution
Prior art date
Application number
PCT/EP1996/003474
Other languages
French (fr)
Other versions
WO1997007139A2 (en
Inventor
Shau-Fong Yen
Mary Sou
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/675,748 external-priority patent/US5773608A/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to AU67426/96A priority Critical patent/AU6742696A/en
Publication of WO1997007139A2 publication Critical patent/WO1997007139A2/en
Publication of WO1997007139A3 publication Critical patent/WO1997007139A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Abstract

A process for sterilizing a polysaccharide composition containing chitosan, a chitosan derivative or a chitin derivative without substantially degrading the polysaccharide. The process has the steps of blending the polysaccharide in a solvent to form a solution or suspension; sterilizing the solution or suspension; dissolving suspended particles, if present; and then aseptically adjusting the pH of the sterilized solution. There is additionally provided a polyol stabilizing agent suitable for the polysaccharide composition.
PCT/EP1996/003474 1995-08-17 1996-08-06 Stabilized chitin derivative compounds WO1997007139A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU67426/96A AU6742696A (en) 1995-08-17 1996-08-06 Stabilized chitin derivative compounds

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51642095A 1995-08-17 1995-08-17
US08/516,420 1995-08-17
US08/675,748 US5773608A (en) 1995-08-17 1996-07-03 Process for preparing stabilized chitin derivative compounds
US08/675,748 1996-07-03

Publications (2)

Publication Number Publication Date
WO1997007139A2 WO1997007139A2 (en) 1997-02-27
WO1997007139A3 true WO1997007139A3 (en) 1997-04-10

Family

ID=27058839

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/003474 WO1997007139A2 (en) 1995-08-17 1996-08-06 Stabilized chitin derivative compounds

Country Status (2)

Country Link
AU (1) AU6742696A (en)
WO (1) WO1997007139A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005030011A1 (en) * 2005-06-17 2006-12-21 Aesculap Ag & Co. Kg Process for the preparation of sterile polysaccharide solutions
WO2016066195A1 (en) * 2014-10-29 2016-05-06 Laboratoire Medidom Sa Heat-sterilized formulation comprising chitosan and process of preparation thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0180934A2 (en) * 1984-11-06 1986-05-14 DECHEMA Deutsche Gesellschaft für Chemisches Apparatewesen, Chemische Technik und Biotechnologie e.V. Use of coarse granules of layered silicates as adsorbents for proteins
GB2179043A (en) * 1985-08-09 1987-02-25 British Food Manufacturing Ind Foamed products
EP0356060A2 (en) * 1988-08-18 1990-02-28 Minnesota Mining And Manufacturing Company Wound filling compositions
WO1994007999A1 (en) * 1992-09-28 1994-04-14 Brown University Research Foundation Chitosan matrices for encapsulated cells
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
EP0665022A1 (en) * 1994-01-28 1995-08-02 Prodex, Inc. Viscoelastic solution of N,O-carboxymethyl chitosan for ophthalmic use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0180934A2 (en) * 1984-11-06 1986-05-14 DECHEMA Deutsche Gesellschaft für Chemisches Apparatewesen, Chemische Technik und Biotechnologie e.V. Use of coarse granules of layered silicates as adsorbents for proteins
GB2179043A (en) * 1985-08-09 1987-02-25 British Food Manufacturing Ind Foamed products
EP0356060A2 (en) * 1988-08-18 1990-02-28 Minnesota Mining And Manufacturing Company Wound filling compositions
WO1994007999A1 (en) * 1992-09-28 1994-04-14 Brown University Research Foundation Chitosan matrices for encapsulated cells
EP0665022A1 (en) * 1994-01-28 1995-08-02 Prodex, Inc. Viscoelastic solution of N,O-carboxymethyl chitosan for ophthalmic use
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system

Also Published As

Publication number Publication date
WO1997007139A2 (en) 1997-02-27
AU6742696A (en) 1997-03-12

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