WO1995026212A1 - A method and an apparatus for training a patient to use an inhaler - Google Patents

A method and an apparatus for training a patient to use an inhaler Download PDF

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Publication number
WO1995026212A1
WO1995026212A1 PCT/SE1995/000315 SE9500315W WO9526212A1 WO 1995026212 A1 WO1995026212 A1 WO 1995026212A1 SE 9500315 W SE9500315 W SE 9500315W WO 9526212 A1 WO9526212 A1 WO 9526212A1
Authority
WO
WIPO (PCT)
Prior art keywords
inhaler
patient
dose
inhalation flow
inhalation
Prior art date
Application number
PCT/SE1995/000315
Other languages
French (fr)
Inventor
Nils Göran MARNFELDT
Johan Mats Bertil Waldeck
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Priority to AU21545/95A priority Critical patent/AU2154595A/en
Publication of WO1995026212A1 publication Critical patent/WO1995026212A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/21General characteristics of the apparatus insensitive to tilting or inclination, e.g. spill-over prevention
    • A61M2205/215Tilt detection, e.g. for warning or shut-off
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated

Definitions

  • the present invention relates to a method and an apparatus for training a patient to use an inhaler.
  • the inhalation flow must reach a certain critical limit. Since the patient cannot tell the difference between an inhalation containing a dose of a drug and an inhalation not containing any dose of the drug, it is difficult for him to know whether he has actually received his dose or not. Therefore, it is important that the patient learns how to use the inhaler correctly right from the beginning and also that he and his doctor can check his use of the inhaler occasionally.
  • a first object of the present invention is to provide an apparatus for training a patient to use an inhaler correctly, this apparatus being inexpensive and easy to use and dispensing with the need of any assistance from trained personnel.
  • a second object of the present invention is to provide a method for training a patient to use an inhaler correctly.
  • the apparatus provides interactive directions for the correct use of an inhaler.
  • the apparatus can be used by everyone without any assis ⁇ tance, since the use of it is self-explanatory. Each step to be performed is indicated to the patient in turn, and the inhalation flow is not measured until a correct acti- vation of the inhaler for making a dose available has been detected.
  • the apparatus comprises an inhaler which is similar to the one the patient normally uses or will use so that the training is realistically performed.
  • Fig 1 is a schematic view showing an embodiment of an apparatus according to the present invention
  • Fig 2 is a block diagram, showing electronical compo ⁇ nents of the apparatus in Fig 1;
  • Fig 3 is a flow diagram, showing the operation of the apparatus in Fig 1.
  • a training apparatus substantially consists of an inhaler 1 and a box-shaped portable processing device 2, to which the inhaler is connected by a cable 3.
  • the inhaler 1 is a Turbuhaler® inhaler, the substance container of which is empty or holds an ineffective sub- stance in the form of a dry powder. It has a replaceable mouthpiece 4 made of e.g. plastics, and a gripping ring 5, which is to be turned in order to make a dose available for inhalation.
  • the processing device 2 On its upper side, the processing device 2 is pro- vided with a switch 6 for turning on the apparatus, and a plurality of light-emitting diodes 7-11 for indicating the different steps to be taken as well as the inhalation flow. Furthermore, there is a picture 12 of a Turbuhaler® inhaler with two arrows indicating how the inhaler is to be operated in order to make a dose available, and a picture 13 indicating inhalation through the inhaler. Furthermore, the training apparatus comprises means for detecting the activation of the inhaler in order to make a dose available for inhalation and for detecting the inhalation flow. Such means may be of the kind disclosed in EP 387 222 and will be briefly described in the follo- wing with reference to Fig. 2.
  • a microphone 16 is arranged in the inhaler 1 close to an inhalation channel (not shown) therein.
  • the microphone 16 is connected to processing means in the processing device 2 by the cable 3.
  • the microphone 16 detects the characteristic click sound created when the gripping ring 5 is turned, as well as the sound of the airflow at an inhalation. These sig ⁇ nals are transferred to the processing device 2 via the cable 3.
  • a first branch 14 of the processing device which is adapted to process the click sound, comprises a rectifier 24 which rectifies the click sound signal.
  • the rectifier 24 is connected to an amplifier 25, which amplifies the rectified signal to about 1 V.
  • the amplified signal is input into a puls stretcher 26, which stretches the ampli ⁇ fied signal to a signal which can be recorded as a valid activation of the inhaler in a processor 27.
  • a second branch 15 of the processing device which is adapted to process the inhalation flow signal, comprises a band pass filter 18, which passes a signal within a limi ⁇ ted frequency range.
  • the filtered signal is input into an amplifier 19, which amplifies the signal to about 1 V.
  • the amplified signal is rectified and low-pass filtered in a detector 20 so that the envelope of the signal is obtai- ned.
  • the envelope signal which represents the momentary inhalation flow, is A/D-converted in a A/D-con- verter 22 before being input into the processor 27.
  • the processor 27 In addition to the inputs from the first and second branches 14, 15, the processor 27 have outputs to the LED's 7-11 on the upper side.
  • the processor 27 detects (step 30) that the training apparatus has been turned on by the pressing of the switch 6, it turns on all the LED's 7-11 for a short while and measures the battery voltage to check whether it is sufficient for performing one or more training cycles (step 31). If the battery is discharged, the processor 27 turns off the apparatus (step 32), whereas if the battery is sufficiently charged, the processor 27 turns on the LED 7 to indicate that the gripping ring 5 is to be turned in order to make a dose available (step 33).
  • the pro ⁇ cessor receives a signal which represents a proper turning of the gripping ring 5 as detected by the microphone 16 (step 34), it turns off the LED 7 and turns on the LED 8 to urge the patient to inhale through the inhaler (step 35).
  • the sound of the inhalation flow is detected by the micro ⁇ phone (step 36).
  • the signal from the microphone 16 is pro ⁇ Registered in the second branch 15 and input into the pro- cessor 27, which determines the size of the inhalation flow (step 37) and turns on one or more of the LEDs 9-11, each LED corresponding to a different inhalation flow achieved.
  • the first LED 9 may be turned on at an inhalation flow of 30 1/min, the second LED 10 at 40 1/min and the third LED 11 at 60 1/min.
  • the processing device comprises a calibration switch arranged inside its cover.
  • the calibration switch is operable from the outside of the cover by means of a magnetic element.
  • the processor 27 turns on the first LED 9.
  • the turning-on level of the first LED 9 can be set by feeding a flow corresponding to the desired turning-on level through the inhaler and, at the same time, pressing the switch 6.
  • the processor turns off the first LED 9 and turns on the second LED 10, the level of which may now be set.
  • the level of the third LED 11 may be set in the same way.
  • the calibrated turning-on levels of the LEDs are stored in a non-volatile memory 28, from which they are fetched when the processor 27 determines which LED(s) to turn on for indicating the inhalation flow. Since it is important that the inhaler is held in a substantially vertical position, at least not deviating more than 45 degrees from the vertical, when the inhaler is activated for making a dose available, the inhaler may, as a further feature, be provided with a position trans- ducer. The position transducer may be connected to the processing device 2 via the cable 3.
  • the processing device 2 need to detect both the click sound created when the inhaler is activated for making a dose available and a correct position of the inhaler during the activation, in order that it shall turn on the LED 8 for urging the patient to inhale through the inhaler.
  • a microphone is used for the detection of the activation of the inhaler and for the detection of the inhalation flow.
  • other means such as a pressure transducer, can be used.
  • the method and the apparatus according to the present invention can be used to train a person to use any kind of inhaler, where first the dose is made available for inha- lation and then the inhalation is performed.
  • the inhaler may be a breath-activated dry powder inhaler, in particular a Turbuhaler® inhaler.

Abstract

An apparatus for training a person to use an inhaler comprises such an inhaler connected to a processing device. The inhaler comprises means for detecting when the inhaler is activated for making a dose of a drug available for inhalation and means for detecting the inhalation flow through the inhaler. The processing device comprises means for indicating to the patient how the inhaler is to be activated in order to make a dose available and means for urging the patient to perform such an activation. The latter means are activated when the apparatus is turned on and deactivated when a proper activation of the inhaler is detected. The processing device further comprises means for urging the patient to inhale through the inhaler. These means are activated when a proper activation of the inhaler is detected and deactivated when an inhalation flow is detected. The measured inhalation flow is indicated by indication means on the processing device. A method for training a person to use an inhaler is also disclosed.

Description

A METHOD AND AN APPARATUS FOR TRAINING A PATIENT TO USE AN INHALER
The present invention relates to a method and an apparatus for training a patient to use an inhaler.
In order that a breath-activated dry powder inhaler should release a dose of a drug contained therein and the dose should reach far enough into the lungs of the patient inhaling through the inhaler, the inhalation flow must reach a certain critical limit. Since the patient cannot tell the difference between an inhalation containing a dose of a drug and an inhalation not containing any dose of the drug, it is difficult for him to know whether he has actually received his dose or not. Therefore, it is important that the patient learns how to use the inhaler correctly right from the beginning and also that he and his doctor can check his use of the inhaler occasionally.
Today, there does not exist any suitable apparatus for training and checking the use of a breath-activated dry powder inhaler. Sometimes, an inhaler is connected to equipment for performing pulmonary function tests (PF ). The inhalation flow is displayed as a function of time on a screen, and a doctor assesses whether the inhalation is correctly performed. However, the PFT equipment is very expensive and may thus be used only at hospitals and the like. Furthermore, a person must be present to instruct the patient, operate the equipment and assess the result. Accordingly, a first object of the present invention is to provide an apparatus for training a patient to use an inhaler correctly, this apparatus being inexpensive and easy to use and dispensing with the need of any assistance from trained personnel.
A second object of the present invention is to provide a method for training a patient to use an inhaler correctly. These objects are achieved by an apparatus and a method having the features recited in appended claims 1 and 16, respectively.
The apparatus according to the invention provides interactive directions for the correct use of an inhaler. The apparatus can be used by everyone without any assis¬ tance, since the use of it is self-explanatory. Each step to be performed is indicated to the patient in turn, and the inhalation flow is not measured until a correct acti- vation of the inhaler for making a dose available has been detected. The apparatus comprises an inhaler which is similar to the one the patient normally uses or will use so that the training is realistically performed.
One embodiment of the apparatus and the method accor- ding to the present invention will now be described in more detail with reference to the accompanying drawings, in which
Fig 1 is a schematic view showing an embodiment of an apparatus according to the present invention; Fig 2 is a block diagram, showing electronical compo¬ nents of the apparatus in Fig 1; and
Fig 3 is a flow diagram, showing the operation of the apparatus in Fig 1.
As appears from Fig 1, a training apparatus according to the present invention substantially consists of an inhaler 1 and a box-shaped portable processing device 2, to which the inhaler is connected by a cable 3.
The inhaler 1 is a Turbuhaler® inhaler, the substance container of which is empty or holds an ineffective sub- stance in the form of a dry powder. It has a replaceable mouthpiece 4 made of e.g. plastics, and a gripping ring 5, which is to be turned in order to make a dose available for inhalation.
On its upper side, the processing device 2 is pro- vided with a switch 6 for turning on the apparatus, and a plurality of light-emitting diodes 7-11 for indicating the different steps to be taken as well as the inhalation flow. Furthermore, there is a picture 12 of a Turbuhaler® inhaler with two arrows indicating how the inhaler is to be operated in order to make a dose available, and a picture 13 indicating inhalation through the inhaler. Furthermore, the training apparatus comprises means for detecting the activation of the inhaler in order to make a dose available for inhalation and for detecting the inhalation flow. Such means may be of the kind disclosed in EP 387 222 and will be briefly described in the follo- wing with reference to Fig. 2.
A microphone 16 is arranged in the inhaler 1 close to an inhalation channel (not shown) therein. The microphone 16 is connected to processing means in the processing device 2 by the cable 3. The microphone 16 detects the characteristic click sound created when the gripping ring 5 is turned, as well as the sound of the airflow at an inhalation. These sig¬ nals are transferred to the processing device 2 via the cable 3. A first branch 14 of the processing device, which is adapted to process the click sound, comprises a rectifier 24 which rectifies the click sound signal. The rectifier 24 is connected to an amplifier 25, which amplifies the rectified signal to about 1 V. The amplified signal is input into a puls stretcher 26, which stretches the ampli¬ fied signal to a signal which can be recorded as a valid activation of the inhaler in a processor 27.
A second branch 15 of the processing device, which is adapted to process the inhalation flow signal, comprises a band pass filter 18, which passes a signal within a limi¬ ted frequency range. The filtered signal is input into an amplifier 19, which amplifies the signal to about 1 V. The amplified signal is rectified and low-pass filtered in a detector 20 so that the envelope of the signal is obtai- ned. Then, the envelope signal, which represents the momentary inhalation flow, is A/D-converted in a A/D-con- verter 22 before being input into the processor 27. In addition to the inputs from the first and second branches 14, 15, the processor 27 have outputs to the LED's 7-11 on the upper side.
The operation of the apparatus shown in Figs 1 and 2 will now be described with reference to the flow diagram in Fig. 3.
When the processor 27 detects (step 30) that the training apparatus has been turned on by the pressing of the switch 6, it turns on all the LED's 7-11 for a short while and measures the battery voltage to check whether it is sufficient for performing one or more training cycles (step 31). If the battery is discharged, the processor 27 turns off the apparatus (step 32), whereas if the battery is sufficiently charged, the processor 27 turns on the LED 7 to indicate that the gripping ring 5 is to be turned in order to make a dose available (step 33). When the pro¬ cessor receives a signal which represents a proper turning of the gripping ring 5 as detected by the microphone 16 (step 34), it turns off the LED 7 and turns on the LED 8 to urge the patient to inhale through the inhaler (step 35). When the patient inhales through the inhaler, the sound of the inhalation flow is detected by the micro¬ phone (step 36). The signal from the microphone 16 is pro¬ cessed in the second branch 15 and input into the pro- cessor 27, which determines the size of the inhalation flow (step 37) and turns on one or more of the LEDs 9-11, each LED corresponding to a different inhalation flow achieved. As an example, the first LED 9 may be turned on at an inhalation flow of 30 1/min, the second LED 10 at 40 1/min and the third LED 11 at 60 1/min.
The levels at which the different LEDs are turned on may be changed without opening the processing device 2. To this end, the processing device comprises a calibration switch arranged inside its cover. The calibration switch is operable from the outside of the cover by means of a magnetic element. To transfer the apparatus to a calibra¬ tion mode both the calibration switch and the switch 6 must be activated at the same time. When the calibration mode is entered, the processor 27 turns on the first LED 9. Then, the turning-on level of the first LED 9 can be set by feeding a flow corresponding to the desired turning-on level through the inhaler and, at the same time, pressing the switch 6. When the level of the the first LED 9 has been set, the processor turns off the first LED 9 and turns on the second LED 10, the level of which may now be set. Finally, the level of the third LED 11 may be set in the same way.
The calibrated turning-on levels of the LEDs are stored in a non-volatile memory 28, from which they are fetched when the processor 27 determines which LED(s) to turn on for indicating the inhalation flow. Since it is important that the inhaler is held in a substantially vertical position, at least not deviating more than 45 degrees from the vertical, when the inhaler is activated for making a dose available, the inhaler may, as a further feature, be provided with a position trans- ducer. The position transducer may be connected to the processing device 2 via the cable 3. In this case, the processing device 2 need to detect both the click sound created when the inhaler is activated for making a dose available and a correct position of the inhaler during the activation, in order that it shall turn on the LED 8 for urging the patient to inhale through the inhaler.
In the embodiment described above a microphone is used for the detection of the activation of the inhaler and for the detection of the inhalation flow. Alternati- vely, other means, such as a pressure transducer, can be used.
The method and the apparatus according to the present invention can be used to train a person to use any kind of inhaler, where first the dose is made available for inha- lation and then the inhalation is performed. For instance, the inhaler may be a breath-activated dry powder inhaler, in particular a Turbuhaler® inhaler.

Claims

1. An apparatus for training a patient to correctly use an inhaler, which is adapted to release a dose of a drug when the patient inhales through the inhaler, with a sufficient inhalation flow, c h a r a c t e r i s e d by such an inhaler (1) without any drug, first means (16) for detecting when the patient properly activates the inhaler for making a dose available for release, second means (16) for detecting the inhalation flow through the inhaler, third means (7) for urging the patient to activate the inhaler for making a dose available, fourth means (8) for urging the patient to inhale through the inhaler when a proper activation of the inhaler has been detected, and fifth means (9-11) for indicating the inhalation flow.
2. An apparatus according to claim 1, c h a r a c ¬ t e r i s e d in that the third means (7) are activated when the apparatus is turned on and deactivated when the first means detect a proper activation; and that the fourth means (8) are activated when the first means detect a proper activation and deactivated when the second means detect an inhalation.
3. An apparatus according to claim 1 or 2, c h a - r a c t e r i s e d in that the first means (16) and the second means (16) are arranged in the inhaler and that the third means (7) and the fourth means (8) are arranged in a portable processing device (2), to which the inhaler is connected.
4. An apparatus according to any one of the preceding claims, c h a r a c t e r i s e d by sixth means (12) for indicating to the patient how the inhaler is to be activated in order to make a dose available.
5. An apparatus according to any one of the preceding claims, c h a r a c t e r i s e d in that the first and the second means comprise a microphone (16).
6. An apparatus according to any one of the preceding claims, c h a r a c t e r i s e d in that the first and the second means comprise a pressure gauge.
7. An apparatus according to any one of the preceding claims, c h a r a c t e r i s e d in that the first means comprise a position transducer;
8. An apparatus according to any one of the preceding claims, c h a r a c t e r i s e d in that the third and the fourth means each comprise a lamp (7, 8).
9. An apparatus according to any one of claims 4-8, c h a r a c t e r i s e d in that the sixth means comprise a pictorial indication (12) of how to activate the inhaler in order to make a dose available.
10. An apparatus according to any one of the pre- ceding claims, c h a r a c t e r i s e d in that the fourth means comprise a pictorial indication (13) of how to inhale through the inhaler.
11. An apparatus according to any one of the pre¬ ceding claims, c h a r a c t e r i s e d in that the fifth means comprise at least two lamps (9-11), each lamp being turned on in response to a different inhalation flow measured b *y the second means.
12. An apparatus according to claim 11, c h a ¬ r a c t e r i s e d by switching means for setting the apparatus in a calibration mode for setting the different inhalation flows at which the lamps (9-11) are turned on, said switching means being arranged inside the processing device but being operable from outside the processing device.
13. An apparatus according to any one of the pre¬ ceding claims, c h a r a c t e r i s e d in that the fifth means (9-11) comprise means for indicating whether the inhalation flow was sufficient to release the dose or not.
14. An apparatus according to any one of the pre¬ ceding claims, c h a r a c t e r i s e d in that the inhaler is a breath-activated dry powder inhaler.
15. An apparatus according to any one of the pre¬ ceding claims, c h a r a c t e r i s e d in that the inhaler is a Turbuhaler® inhaler.
16. A method for training a patient to use an in- haler, which is adapted to release a dose of a drug when the patient inhales through the inhaler with a sufficient inhalation flow, c h a r a c t e r i s e d by the steps of
- providing a training apparatus, comprising such an inha- ler (1) without any drug,
- providing an invitation to the patient to activate the inhaler in order to make a dose of a drug available for release,
- detecting a proper activation of the inhaler for making a dose available,
- providing, in response to the detection of a proper activation, an invitation to the patient to inhale through the inhaler,
- detecting the inhalation flow through the inhaler, - indicating the inhalation flow to the patient.
17. A method according to claim 16, c h a r a c ¬ t e r i s e d by the further steps of
- terminating, in response to the detection of a proper activation, said invitation to activate the inhaler, and - terminating, in response to the detection of an inhala¬ tion flow, said invitation to inhale.
18. A method according to claim 16 or 17, c h a ¬ r a c t e r i s e d in that detecting a proper activation of the inhaler comprises detecting a correct position of the inhaler when the inhaler is activated for making a dose of a drug available.
PCT/SE1995/000315 1994-03-25 1995-03-24 A method and an apparatus for training a patient to use an inhaler WO1995026212A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU21545/95A AU2154595A (en) 1994-03-25 1995-03-24 A method and an apparatus for training a patient to use an inhaler

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401020A SE9401020D0 (en) 1994-03-25 1994-03-25 Method and apparatus in connection with an inhaler
SE9401020-4 1994-03-25

Publications (1)

Publication Number Publication Date
WO1995026212A1 true WO1995026212A1 (en) 1995-10-05

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5957125A (en) * 1996-11-05 1999-09-28 Medical Safety Products, Inc. Apparatus for indicating proper orientation for oral and nasal inhalers
EP0916356A3 (en) * 1997-11-12 2000-03-01 Miat S.P.A. Dose dispenser for substances in powder or granular form
WO2000069496A1 (en) * 1999-05-18 2000-11-23 Glaxo Group Limited Medication dispenser
GB2406283A (en) * 2003-09-24 2005-03-30 Altana Pharma Ag Compliance monitor for a drug delivery device and method of using the compliance monitor.
WO2011083377A1 (en) * 2010-01-07 2011-07-14 Koninklijke Philips Electronics N.V. Respiratory drug delivery apparatus including a feedback and compliance device
CN104707226A (en) * 2015-04-06 2015-06-17 上海朔茂网络科技有限公司 Operation method of inhalable medication training device
WO2015154865A3 (en) * 2014-04-07 2015-12-17 Boehringer Ingelheim International Gmbh Inhalation training device and system for practicing of an inhalation process of a patient
WO2016043601A1 (en) * 2014-09-15 2016-03-24 Adherium (Nz) Ltd Adherence monitor for a dry powder medicament delivery device
US10258753B2 (en) 2012-10-04 2019-04-16 Boehringer Ingelheim International Gmbh System, method, use and information storage medium for practicing of an inhalation process
US10456536B2 (en) 2014-03-25 2019-10-29 Koninklijke Philips N.V. Inhaler with two microphones for detection of inhalation flow

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387222A1 (en) * 1989-03-07 1990-09-12 Aktiebolaget Draco Device in connection with an inhaler
WO1992015353A2 (en) * 1991-03-05 1992-09-17 Miris Medical Corporation Delivery of aerosol medications for inspiration
WO1993012823A2 (en) * 1991-12-20 1993-07-08 Circadian, Inc. Intelligent inhaler providing feedback to both patient

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0387222A1 (en) * 1989-03-07 1990-09-12 Aktiebolaget Draco Device in connection with an inhaler
WO1992015353A2 (en) * 1991-03-05 1992-09-17 Miris Medical Corporation Delivery of aerosol medications for inspiration
WO1993012823A2 (en) * 1991-12-20 1993-07-08 Circadian, Inc. Intelligent inhaler providing feedback to both patient

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5957125A (en) * 1996-11-05 1999-09-28 Medical Safety Products, Inc. Apparatus for indicating proper orientation for oral and nasal inhalers
EP0916356A3 (en) * 1997-11-12 2000-03-01 Miat S.P.A. Dose dispenser for substances in powder or granular form
WO2000069496A1 (en) * 1999-05-18 2000-11-23 Glaxo Group Limited Medication dispenser
US8464707B2 (en) 2003-09-24 2013-06-18 Takeda Gmbh Compliance monitor and method
GB2406283B (en) * 2003-09-24 2006-04-05 Altana Pharma Ag Compliance monitor and method
GB2406283A (en) * 2003-09-24 2005-03-30 Altana Pharma Ag Compliance monitor for a drug delivery device and method of using the compliance monitor.
WO2011083377A1 (en) * 2010-01-07 2011-07-14 Koninklijke Philips Electronics N.V. Respiratory drug delivery apparatus including a feedback and compliance device
US9352107B2 (en) 2010-01-07 2016-05-31 Koninklijke Philips N.V. Respiratory drug delivery apparatus including a feedback and compliance device
US10258753B2 (en) 2012-10-04 2019-04-16 Boehringer Ingelheim International Gmbh System, method, use and information storage medium for practicing of an inhalation process
US10456536B2 (en) 2014-03-25 2019-10-29 Koninklijke Philips N.V. Inhaler with two microphones for detection of inhalation flow
WO2015154865A3 (en) * 2014-04-07 2015-12-17 Boehringer Ingelheim International Gmbh Inhalation training device and system for practicing of an inhalation process of a patient
CN106132466A (en) * 2014-04-07 2016-11-16 勃林格殷格翰国际有限公司 Suction training devices and the system of suction process is practised for patient
EA033261B1 (en) * 2014-04-07 2019-09-30 Бёрингер Ингельхайм Интернациональ Гмбх Inhalation training device and system for practicing an inhalation process
WO2016043601A1 (en) * 2014-09-15 2016-03-24 Adherium (Nz) Ltd Adherence monitor for a dry powder medicament delivery device
CN104707226A (en) * 2015-04-06 2015-06-17 上海朔茂网络科技有限公司 Operation method of inhalable medication training device

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