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WO1995021654A1 - Device for phono-electrophoresis - Google Patents

Device for phono-electrophoresis Download PDF

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Publication number
WO1995021654A1
WO1995021654A1 PCT/RU1994/000023 RU9400023W WO9521654A1 WO 1995021654 A1 WO1995021654 A1 WO 1995021654A1 RU 9400023 W RU9400023 W RU 9400023W WO 9521654 A1 WO9521654 A1 WO 9521654A1
Authority
WO
WIPO (PCT)
Prior art keywords
πatsienτa
τela
ποdlezhaschey
vοzdeysτviyu
τem
Prior art date
Application number
PCT/RU1994/000023
Other languages
French (fr)
Russian (ru)
Inventor
Vladimir Ivanovich Ivanov
Original Assignee
Vladimir Ivanovich Ivanov
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vladimir Ivanovich Ivanov filed Critical Vladimir Ivanovich Ivanov
Priority to RU94005014/14A priority Critical patent/RU94005014A/en
Priority to RU94004927 priority
Priority to RU94004927/14A priority patent/RU94004927A/en
Priority to RU94005014 priority
Publication of WO1995021654A1 publication Critical patent/WO1995021654A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Abstract

The proposed device for phono-electrophoresis comprises: an ultrasonic emitter (1); a hollow cylindrical body (2) which acts as an active electrode and in which is housed a piezo-electric element (3) on whose outer surface in relation to the surface of the body (4) of the patient undergoing electro-ultrasonic treatment there is a protective element (7) made of an ultrasound-conducting material; a device (10) for creating acoustic contact between the protective element (7) and the surface of the patient's body (4); a device (16) for minimizing the therapeutic agent (12) introduced into the cavity (13) formed by the protective element (7) and the surface of the patient's body (4), said device also serving as the device (10) for creating acoustic contact; and a passive electrode (17) placed on the patient's body (4). In the example shown, the device (16) has a semi-permeable membrane (42) and a spring-loaded bellows system (46).

Description

Claims

- 13 -
ΦΟΡΜULΑ IZΟΕΡΕGΕΗSH
I. Usτροysτvο for φοnοeleκτροφορeza, sοdeρzhaschee ulτρazvuκοvοy izluchaτel (I), in ποlοm tsilindρichesκοm κορπuse (2) κοτοροgο, which is aκτivnym eleκτροdοm, ρazmeschen πezοelemenτ (3) for naρuzhnοy ποveρχnοsτi κοτο-
5 ροgο πο οτnοsheniyu κ ποveρχnοsτi τela (4) πatsienτa, ποd- lying eleκτροulτρazvuκοvοmu vοzdeysτviyu, imeeτsya zaschiτ- ny elemenτ (7) of προvοdyaschegο ulτρazvuκ maτeρiala, sρed- sτvο (10) between aκusτichesκοgο κοnτaκτa zaschiτnym τοm elements (7) and ποveρχnοsτyu τela (4) πatsienτa, ποdlezhaschey
Yu eleκτροulτρazvuκοvοmu vοzdeysτviyu, vyποlnennοe of di- eleκτρichesκοgο maτeρiala, sοedinennοe with κορπusοm (2) izluchaτelya (I) and being deρzhaτelem izluchaτelya (I), sρed- sτvο (II) vvοda leκaρsτvennοgο πρeπaρaτa in ποlοsτ (13) οbρazuemuyu zaschiτnym elemenτοm ( 7) and ποveρχnοsτyu τela (4)
15 πatsienτa, ποdlezhaschey eleκτροulτρazvuκοvοmu vοzdeysτviyu, sρedsτvο (14) vyvοda leκaρsτvennοgο πρeπaρaτa of uκazan- nοy ποlοsτi (13) sρedsτvο (15) κοnτροlya presence leκaρsτvennοgο πρeπaρaτa (12) eτοy ποlοsτi (13) and πassivny eleκτροd (7) ρasποlagaemy on τele (4) πatsienτa, ο τ -
20 l and h and Yusch ee with I τem, chτο therein πρedusmοτρenο sρed- sτvο (16) to minimize leκaρsτvennοgο πρeπaρaτa (12) in vvο- dimοgο ποlοsτ (13) οbρazuemuyu zaschiτnym elemenτοm (7) and ποveρχnοsτyu τela (4) πatsienτa , ποdlezhaschey eleκτρο- ulτρazvuκοvοmu vοzdeysτviyu serving οdnοvρemennο and
25 sρedsτvοm (10) and aκusτichesκοgο κοnτaκτa sοedinennοe with κορπusοm (2) izluchaτelya.
?. Usτροysτvο πο π.Ι, ο τ L and b as e e a Yusch I τem, chτο sρedsτvο (16) to minimize leκaρsτvennοgο πρeπa- ρaτa (12) sοdeρzhiτ ποly tsilindρichesκy κορπus (Ι) having
30 dnischv (21). πρisποsοblenny for geρmeτichnοgο κοnτaκτa with ποveρχnοsτyu τela (4) πatsienτa, κοaκsialnο usτanοvlenny with κορπusοm (2) ulτρazvuκοvοgο izluchaτelya (I) and from vyποl- nenny dvuχ κοaκsialnο usτanοvlennyχ ποlyχ tsilindροv
(19), (20), οdni τορtsy κοτορy χ sοedineny between sοbοy 35 οbρazuya Part of the bottom (21) κορπusa (18) and dρugie τορsch (22), (23) tsilindροv (.19), (20) tsilindρichesκοgο κορπusa - 14 - (18) in naπρavleny sτοροnu ποveρ χ nοsτi τela (4) πatsienτa, ποdlezhaschey eleκτροulτρazvuκοvοmu vοzdeysτviyu, πρi eτοm in tsilindρichesκοm κορπuse (18) vyποlneny ποd uglοm κ προ- dοlnοy οsi (25) κορπusa (2) izluchaτelya (I) κanaly sρed - 5 sτva (II) vvοda leκaρsτvennοgο πρeπaρaτa (12) sρedsτ- va (14) vyvοda leκaρsτvennοgο πρeπaρaτa (12) and κanal (26) for sοzdaniya vaκuuma ποlοsτi (27) between οbρazοvannοy lindρami The cylinder (19), (20) κο ρπusa (18).
3. Usτροysτvο πο π.2, ο τ L and h and i e with the capstan τem, Yu chτο κορπus (18) sρedsτva (16) to minimize leκaρsτvennοgο πρeπaρaτa (12) of vyποlnen maτeρiala, οbesπechivayuschegο κοnτροl for sοblyudeniem aκusτichesκοgο κοnτaκτa in ποlοsτi (13 ) οbρazuemοy zaschiτnym elemenτοm (7) of vyποlnennym dieleκτρichesκοgο maτeρiala and ποveρχnοsτyu τela (4) πatsi- 15 enτa, ποdlezhaschey eleκτροulτρazvuκοvοmu vοzdeysτviyu.
4. Usτροysτvο πο π.Ι, ο τ L and b as e e a Yusch I τem, chτο sρedsτvο (16) to minimize leκaρsτvennοgο πρeπaρaτa (12) sοdeρzhiτ ποluπροnitsaemuyu membρanu (42) ρasποlοzhennuyu sο sτοροny τορtsa (43) egο ποlοgο tsilindρichesκοgο κορπusa (44)
20 and ποdπρuzhinenny silφοn (46) for sοzdaniya vyπuκlοy φορ- we membρany (42), in naπρavlennοy sτοροnu ποveρχnοsτi τe- la (4) πatsienτa, ποdlezhaschey eleκτροulτρazvuκοvοmu vοz- deysτviyu associated with membρanοy (42).
5. Usτροysτvο πο π.4, ο τ L and b as e e a Yusch I τem 5 το ποdπρuzhinenny silφοn (46) on usτanοvlen τορtse (43) ποlοgο tsilindρichesκοgο κορπusa (44) sρedsτva (16) minimizes tion leκaρsτvennοgο πρeπaρaτa, and membρana (42) with sοedinena ποslednim οτ τορtsa (43) κορπusa (44) gοφροm (47) on silφο- (46) and zaschiτny elemenτ (7) of vyποlnen dieleκτρiches- 30 κοgο maτeρiala.
6. Usτροysτvο πο π.4, ο τ L and b as e e a Yusch I τem, chτο membρana (42) on zaκρeπlena neποsρedsτvennο τορtse (43) ποlοgο tsilindρichesκοgο κορπusa (44) sρedsτva (16) minimizing leκaρsτvennοgο πρeπaρaτa and ποdπρuzhinenny strong
35 φοn (51) sοedinen sο sρedsτvοm (15) κοnτροlya presence leκaρsτvennοgο πρeπaρaτa (12) and οbem silφοna (51) ρaven amount οbemοv ποlοsτi (13) οbρazuemοy zaschiτnym elemenτοm (7) and ποveρχnοsτyu τela (4) πatsienτa, ποdlezhaschey eleκτρο- - 15 - ulτρazvuκοvοmu vοzdeysτviyu - membρanοy (42) and sρedsτva (15) κοnτροlya presence leκaρsτvennοgο πρeπaρaτa (12) and zaschiτny elemenτ (7) of vyποlnen dieleκτρichesκοgο maτeρi- ala. 5 7. Usτροysτvο πο lyubοmu of π.π.Ι-6, ο τ L and Yusch ich th e I with τem, chτο therein πρedusmοτρena πaρa individualnyχ eleκτροdοv (5,6) πeρvy (6) of κοτορyχ ρasποlοzhen on vnuτρenney ποveρχnοsτi πezοelemenτa (3) πο οτnοsheniyu κ ποveρ χ nοsτi τela (4) πatsienτa, ποdlezhaschey eleκτροulτρa-
Yu zvuκοvοmu vοzdeysτviyu and vτοροy eleκτροd (5) on ρasποlοzhen naρuzhnοy ποveρχnοsτi πezοelemenτa (3) πο οτnοsheniyu κ ποveρχnοsτi τela (4) πatsienτa, ποdlezhaschey eleκτροulτρazvu- κοvοmu vοzdeysτviyu, πρi eτοm zaschiτny elemenτ (7) on ρasποlοzhen vτοροm eleκτροde ( 5) and vyποlnen of προvοdyaschegο
15 ulτρazvuκ dieleκτρichesκο ο maτeρiala.
PCT/RU1994/000023 1994-02-10 1994-02-10 Device for phono-electrophoresis WO1995021654A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
RU94005014/14A RU94005014A (en) 1994-02-10 1994-02-10 Apparatus for phonoelectrophoresis
RU94004927 1994-02-10
RU94004927/14A RU94004927A (en) 1994-02-10 1994-02-10 Apparatus for phonoelectrophoresis
RU94005014 1994-02-10

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU66919/94A AU6691994A (en) 1994-02-10 1994-02-10 Device for phono-electrophoresis

Publications (1)

Publication Number Publication Date
WO1995021654A1 true WO1995021654A1 (en) 1995-08-17

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU1994/000023 WO1995021654A1 (en) 1994-02-10 1994-02-10 Device for phono-electrophoresis

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AU (1) AU6691994A (en)
WO (1) WO1995021654A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1136A (en) * 1996-12-18 2003-01-31 Vertex Pharmaceuticals Incorpo """Substituted nitrogen containing heterocycles as inhibitors of P38 protein kinase""."
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU935109A1 (en) * 1979-10-10 1982-06-15 Тартуский Ордена Трудового Красного Знамени Государственный Университет Apparatus for ultrasonic therapy
SU1003853A1 (en) * 1980-03-17 1983-03-15 Белорусский Научно-Исследовательский Институт Неврологии,Нейрохирургии И Физиотерапии Device for electrophonoresis
EP0254965A1 (en) * 1986-07-31 1988-02-03 Alza Corporation Programmable constant current source transdermal drug delivery system
EP0378132A2 (en) * 1989-01-09 1990-07-18 S.L. Cit Ionofor A device for the administration of medication by iontopheresis for local - regional treatment.
US5002527A (en) * 1988-04-14 1991-03-26 Inventor's Funding Corp. Ltd. Transdermal drug delivery applicators

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU935109A1 (en) * 1979-10-10 1982-06-15 Тартуский Ордена Трудового Красного Знамени Государственный Университет Apparatus for ultrasonic therapy
SU1003853A1 (en) * 1980-03-17 1983-03-15 Белорусский Научно-Исследовательский Институт Неврологии,Нейрохирургии И Физиотерапии Device for electrophonoresis
EP0254965A1 (en) * 1986-07-31 1988-02-03 Alza Corporation Programmable constant current source transdermal drug delivery system
US5002527A (en) * 1988-04-14 1991-03-26 Inventor's Funding Corp. Ltd. Transdermal drug delivery applicators
EP0378132A2 (en) * 1989-01-09 1990-07-18 S.L. Cit Ionofor A device for the administration of medication by iontopheresis for local - regional treatment.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1136A (en) * 1996-12-18 2003-01-31 Vertex Pharmaceuticals Incorpo """Substituted nitrogen containing heterocycles as inhibitors of P38 protein kinase""."
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin

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Publication number Publication date
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