WO1995016036A3 - CHAINE β DE RECEPTEURS D'IFN-η ET LEURS DERIVES - Google Patents

CHAINE β DE RECEPTEURS D'IFN-η ET LEURS DERIVES Download PDF

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Publication number
WO1995016036A3
WO1995016036A3 PCT/US1994/014277 US9414277W WO9516036A3 WO 1995016036 A3 WO1995016036 A3 WO 1995016036A3 US 9414277 W US9414277 W US 9414277W WO 9516036 A3 WO9516036 A3 WO 9516036A3
Authority
WO
WIPO (PCT)
Prior art keywords
ifn
ηreceptor
derivatives
chain
invention concerns
Prior art date
Application number
PCT/US1994/014277
Other languages
English (en)
Other versions
WO1995016036A2 (fr
Inventor
Michel Aguet
Ruth Boehni
Silvio Hemmi
Original Assignee
Michel Aguet
Ruth Boehni
Silvio Hemmi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michel Aguet, Ruth Boehni, Silvio Hemmi filed Critical Michel Aguet
Priority to EP95908418A priority Critical patent/EP0733111A1/fr
Priority to JP7516386A priority patent/JPH09506263A/ja
Publication of WO1995016036A2 publication Critical patent/WO1995016036A2/fr
Publication of WO1995016036A3 publication Critical patent/WO1995016036A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7156—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention se rapporte à de nouveaux polypeptides constituant des sous-unités de récepteurs. Cette invention concerne plus particulièrement de nouvelles protéines transmembranaires qui appartiennent à la famille des récepteurs de l'interféron et qui sont des cofacteurs à spécificité d'espèce nécessaires pour la transduction du signal de l'interféron-η (IFN-η).
PCT/US1994/014277 1993-12-09 1994-12-07 CHAINE β DE RECEPTEURS D'IFN-η ET LEURS DERIVES WO1995016036A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP95908418A EP0733111A1 (fr) 1993-12-09 1994-12-07 CHAINE $g(b) DE RECEPTEURS D'IFN-$g(g) ET LEURS DERIVES
JP7516386A JPH09506263A (ja) 1993-12-09 1994-12-07 ＩＦＮ−γレセプターβ−鎖およびその誘導体

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16459693A 1993-12-09 1993-12-09
US08/164,596 1993-12-09

Publications (2)

Publication Number Publication Date
WO1995016036A2 WO1995016036A2 (fr) 1995-06-15
WO1995016036A3 true WO1995016036A3 (fr) 1995-08-31

Family

ID=22595201

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/014277 WO1995016036A2 (fr) 1993-12-09 1994-12-07 CHAINE β DE RECEPTEURS D'IFN-η ET LEURS DERIVES

Country Status (4)

Country Link
EP (1) EP0733111A1 (fr)
JP (1) JPH09506263A (fr)
CA (1) CA2177471A1 (fr)
WO (1) WO1995016036A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0804222A4 (fr) * 1993-08-20 1998-08-12 Univ New Jersey Med Fonction du facteur accessoire de l'interferon gamma et de son recepteur
US20020025316A1 (en) 1995-08-18 2002-02-28 Ferguson Mark Williams James Pharmaceutical composition containing inhibitors of interferon-gamma
GB2304342A (en) * 1995-08-18 1997-03-19 Univ Manchester Pharmaceutical comprising either an inhibitor or a stimulator of interferon gamma
US6586228B1 (en) 1998-03-09 2003-07-01 Schering Corporation Polynucleotides encoding DIRS1
EP1062332A2 (fr) * 1998-03-09 2000-12-27 Schering Corporation Proteines receptrices humaines; reactifs et procedes associes
US6348316B1 (en) 2000-04-12 2002-02-19 Cedars-Sinai Medical Center Genetic testing for determining the risk of pouchitis development
US7608430B2 (en) 2005-07-08 2009-10-27 Regeneron Pharmaceuticals, Inc. Interferon-γ antagonists and therapeutic uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005847A1 (fr) * 1993-08-20 1995-03-02 University Of Medicine & Dentistry Of New Jersey Fonction du facteur accessoire de l'interferon gamma et de son recepteur

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005847A1 (fr) * 1993-08-20 1995-03-02 University Of Medicine & Dentistry Of New Jersey Fonction du facteur accessoire de l'interferon gamma et de son recepteur

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
ANNUAL MEETING OF THE ISICR ON THE INTERFERON SYSTEM, TOKYO, JAPAN ; OCTOBER 24-28 ,1993. *
ANNUAL MEETING OF THE ISICR, TOKYO, JAPAN; OCTOBER 24-28, 1993. *
J. SOH ET AL: "Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor", CELL, vol. 76, 11 March 1994 (1994-03-11), CAMBRIDGE, NA US, pages 793 - 802 *
J. SOH ET AL: "Identification of a yeast artificial chromosome clone encoding an accessory factor for the human interferon gamma receptor: Evidence for multiple accessory factors", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 90, September 1993 (1993-09-01), WASHINGTON US, pages 8737 - 8741 *
J.R. COOK ET AL: "Localization of the human IFN-gamma receptor accessory factor gene and discovery of a new accessory factor by chromosomal fragmentation", JOURNAL OF INTERFERON RESEARCH , VOL. 13, SUPPL. 1,, September 1993 (1993-09-01), pages S49 *
S. HEMMI ET AL: "A novel member of the Interferon receptor family complements functionality of the murine interferon gamma receptor in human cells", CELL, vol. 76, 11 March 1994 (1994-03-11), CAMBRIDGE, NA US, pages 803 - 810 *
S. HEMMI ET AL: "Expression cloning of a species-specific interferon-gamma receptor accessory component", JOURNAL OF INTERFERON RESEARCH VOL. 13 , SUPPL 1, September 1993 (1993-09-01), pages S55 *
U. KALINA ET AL: "The human gamma interferon receptor accessory factor encoded by chromosome 21 transduces the signal for the induction of 2',5'-Oligoadenylate-synthetase, resistance to virus cytopathic effect , and major histocompatibility complex class I antigens", JOURNAL OF VIROLOGY, vol. 67, no. 3, March 1993 (1993-03-01), pages 1702 - 1706 *
Y. HIBINO ET AL: "Expression and reconstitution of a biologically active mouse Interferon gamma receptor in hamster cells", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 11, 15 April 1991 (1991-04-15), BALTIMORE, MD US, pages 6948 - 6951 *

Also Published As

Publication number Publication date
EP0733111A1 (fr) 1996-09-25
WO1995016036A2 (fr) 1995-06-15
JPH09506263A (ja) 1997-06-24
CA2177471A1 (fr) 1995-06-15

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