WO1995004733A1 - (1,3,4)triazolo(1,5-al)pyridine als zwischenprodukte für die synthese von farbstoffen - Google Patents
(1,3,4)triazolo(1,5-al)pyridine als zwischenprodukte für die synthese von farbstoffen Download PDFInfo
- Publication number
- WO1995004733A1 WO1995004733A1 PCT/EP1994/002233 EP9402233W WO9504733A1 WO 1995004733 A1 WO1995004733 A1 WO 1995004733A1 EP 9402233 W EP9402233 W EP 9402233W WO 9504733 A1 WO9504733 A1 WO 9504733A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- possibly
- triazolo
- dyes
- synthesis
- intermediate products
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7506167A JPH09501167A (ja) | 1993-08-10 | 1994-07-07 | 染料の合成用の中間体としての(1,3,4)トリアゾロ(1,5−al)ピリジン |
DE59404361T DE59404361D1 (de) | 1993-08-10 | 1994-07-07 | [1,3,4]triazolo[1,5-al]pyridine als zwischenprodukte für die synthese von farbstoffen |
KR1019950706012A KR100317847B1 (ko) | 1993-08-10 | 1994-07-07 | 염료의합성을위한중간생성물로서사용되는[1,3,4]트리아졸로[1,5-a]피리딘 |
EP94923712A EP0713488B1 (de) | 1993-08-10 | 1994-07-07 | [1,3,4]triazolo[1,5-al]pyridine als zwischenprodukte für die synthese von farbstoffen |
US08/966,968 US6043369A (en) | 1993-08-10 | 1994-07-07 | [1,3,4] Triazolo [1,5-A] pyridines |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEP4326758.0 | 1993-08-10 | ||
DE4326758A DE4326758A1 (de) | 1993-08-10 | 1993-08-10 | [1,3,4]Triazolo[1,5-a]pyridine |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US59231196A Continuation | 1993-08-10 | 1996-02-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995004733A1 true WO1995004733A1 (de) | 1995-02-16 |
Family
ID=6494813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1994/002233 WO1995004733A1 (de) | 1993-08-10 | 1994-07-07 | (1,3,4)triazolo(1,5-al)pyridine als zwischenprodukte für die synthese von farbstoffen |
Country Status (7)
Country | Link |
---|---|
US (1) | US6043369A (de) |
EP (1) | EP0713488B1 (de) |
JP (1) | JPH09501167A (de) |
KR (1) | KR100317847B1 (de) |
DE (2) | DE4326758A1 (de) |
TW (1) | TW353072B (de) |
WO (1) | WO1995004733A1 (de) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5612465A (en) * | 1993-08-13 | 1997-03-18 | Basf Aktiengesellschaft | Phenylazotriazolopyridine dyestuffs |
EP0745107B1 (de) * | 1994-02-18 | 1998-11-04 | Basf Aktiengesellschaft | Triazolopyridinfarbstoffe |
WO2004039877A2 (de) * | 2002-10-28 | 2004-05-13 | Basf Aktiengesellschaft | Stabilisatormischung |
WO2006018727A2 (en) * | 2004-08-18 | 2006-02-23 | Pharmacia & Upjohn Company Llc | Triazolopyridine compounds useful for the treatment of inflammation |
US8252937B2 (en) | 2007-09-14 | 2012-08-28 | Janssen Pharmaceuticals, Inc. | 1,3-disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones |
US8299101B2 (en) | 2007-03-07 | 2012-10-30 | Janssen Pharmaceuticals, Inc. | 1,4-disubstituted 3-cyano-pyridone derivatives and their use as positive mGluR2-receptor modulators |
US8399493B2 (en) | 2004-09-17 | 2013-03-19 | Janssen Pharmaceuticals, Inc. | Pyridinone derivatives and their use as positive allosteric modulators of mGluR2-receptors |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
US8691849B2 (en) | 2008-09-02 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
US8841323B2 (en) | 2006-03-15 | 2014-09-23 | Janssen Pharmaceuticals, Inc. | 1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of MGLUR2-receptors |
US8906939B2 (en) | 2007-03-07 | 2014-12-09 | Janssen Pharmaceuticals, Inc. | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
US8937060B2 (en) | 2009-05-12 | 2015-01-20 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders |
US8946205B2 (en) | 2009-05-12 | 2015-02-03 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US8993591B2 (en) | 2010-11-08 | 2015-03-31 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
US9012448B2 (en) | 2010-11-08 | 2015-04-21 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
US9085577B2 (en) | 2009-05-12 | 2015-07-21 | Janssen Pharmaceuticals, Inc. | 7-aryl-1,2,4-triazolo[4,3-A]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US9114138B2 (en) | 2007-09-14 | 2015-08-25 | Janssen Pharmaceuticals, Inc. | 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′] bipyridinyl-2′-ones |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US9708315B2 (en) | 2013-09-06 | 2017-07-18 | Janssen Pharmaceutica Nv | 1,2,4-triazolo[4,3-a]pyridine compounds and their use as positive allosteric modulators of MGLUR2 receptors |
US10106542B2 (en) | 2013-06-04 | 2018-10-23 | Janssen Pharmaceutica Nv | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors |
US10537573B2 (en) | 2014-01-21 | 2020-01-21 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
US11369606B2 (en) | 2014-01-21 | 2022-06-28 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4329296A1 (de) * | 1993-08-31 | 1995-03-02 | Basf Ag | Azofarbstoffe mit einer Diazokomponente aus der Anilinreihe und Kupplungskomponente aus der Triazolopyridinreihe |
DE19535501A1 (de) * | 1995-09-25 | 1997-03-27 | Bayer Ag | Pyridonmethidazofarbstoffe |
US6303625B1 (en) * | 1998-07-27 | 2001-10-16 | Ortho-Mcneil Pharmaceutical, Inc. | Triazolopyridines for the treatment of thrombosis disorders |
US8198448B2 (en) * | 2006-07-14 | 2012-06-12 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
PE20080403A1 (es) * | 2006-07-14 | 2008-04-25 | Amgen Inc | Derivados heterociclicos fusionados y metodos de uso |
US8217177B2 (en) * | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
WO2008045393A2 (en) * | 2006-10-11 | 2008-04-17 | Amgen Inc. | Imidazo- and triazolo-pyridine compounds and methods of use therof |
US8119658B2 (en) | 2007-10-01 | 2012-02-21 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
US8394823B2 (en) * | 2008-04-11 | 2013-03-12 | Bristol-Myers Squibb Company | Triazolopyridine compounds useful as DGAT1 inhibitors |
MX339302B (es) | 2011-09-15 | 2016-05-19 | Novartis Ag | 3-(quinolin-6-il-tio)-[1,2,4]-triazolo-[4,3-a]-piridinas 6-sustituidas como cinasas de tirosina. |
CN105017248B (zh) * | 2015-06-16 | 2017-07-07 | 浙江工业大学 | 一种[1,2,4]三唑[4,3‑a]吡啶‑3(2H)‑硫酮类化合物的制备方法及其应用 |
CN105017247B (zh) * | 2015-06-16 | 2017-07-07 | 浙江工业大学 | 一种[1,2,4]三唑[4,3‑a]吡啶‑3(2H)‑硫酮衍生物的制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0210648A1 (de) * | 1985-08-01 | 1987-02-04 | Merrell Dow Pharmaceuticals Inc. | 5-Chloro-s-triazolo[4,3-a]pyridin-7-carbonsäuren |
EP0441718A1 (de) * | 1990-01-29 | 1991-08-14 | Rhone-Poulenc Agrochimie | Triazolopyridinverbindungen mit herbizider Wirkung |
US5101028A (en) * | 1989-08-12 | 1992-03-31 | Basf Aktiengesellschaft | (1,2,4)triazolo[2,3-a]pyridines |
-
1993
- 1993-08-10 DE DE4326758A patent/DE4326758A1/de not_active Withdrawn
-
1994
- 1994-07-07 EP EP94923712A patent/EP0713488B1/de not_active Expired - Lifetime
- 1994-07-07 WO PCT/EP1994/002233 patent/WO1995004733A1/de active IP Right Grant
- 1994-07-07 DE DE59404361T patent/DE59404361D1/de not_active Expired - Fee Related
- 1994-07-07 KR KR1019950706012A patent/KR100317847B1/ko not_active IP Right Cessation
- 1994-07-07 US US08/966,968 patent/US6043369A/en not_active Expired - Fee Related
- 1994-07-07 JP JP7506167A patent/JPH09501167A/ja active Pending
- 1994-07-27 TW TW083106862A patent/TW353072B/zh active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0210648A1 (de) * | 1985-08-01 | 1987-02-04 | Merrell Dow Pharmaceuticals Inc. | 5-Chloro-s-triazolo[4,3-a]pyridin-7-carbonsäuren |
US5101028A (en) * | 1989-08-12 | 1992-03-31 | Basf Aktiengesellschaft | (1,2,4)triazolo[2,3-a]pyridines |
EP0441718A1 (de) * | 1990-01-29 | 1991-08-14 | Rhone-Poulenc Agrochimie | Triazolopyridinverbindungen mit herbizider Wirkung |
Non-Patent Citations (4)
Title |
---|
AYMAN: "Ammonium 1,1,3-Tricyano-2-methylprop-2-enide: A novel reagent in heterocyclic synthesis", J.CHEM.RESEARCH SYNOP., 1993, pages 8 - 9 * |
ITO ET AL: "The preparation of 3-Phenyl[1,2,4]triazolo[4,3-a]pyridines and their Benzologs.", BULL.CHEM.SOC.JAPAN, vol. 53, no. 7, 1980, pages 2007 - 11 * |
POTTS AT EL: "1,2,4-triazoles", J.ORG.CHEM., vol. 31, no. 11, 1966, pages 3522 - 27 * |
POTTS ET AL: "1,2,4-Triazoles.", J.ORG.CHEM., vol. 35, no. 3, 1970, pages 808 - 811 * |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5612465A (en) * | 1993-08-13 | 1997-03-18 | Basf Aktiengesellschaft | Phenylazotriazolopyridine dyestuffs |
EP0745107B1 (de) * | 1994-02-18 | 1998-11-04 | Basf Aktiengesellschaft | Triazolopyridinfarbstoffe |
WO2004039877A2 (de) * | 2002-10-28 | 2004-05-13 | Basf Aktiengesellschaft | Stabilisatormischung |
WO2004039877A3 (de) * | 2002-10-28 | 2004-08-26 | Basf Ag | Stabilisatormischung |
WO2006018727A2 (en) * | 2004-08-18 | 2006-02-23 | Pharmacia & Upjohn Company Llc | Triazolopyridine compounds useful for the treatment of inflammation |
WO2006018727A3 (en) * | 2004-08-18 | 2006-07-06 | Pharmacia & Upjohn Co Llc | Triazolopyridine compounds useful for the treatment of inflammation |
US8399493B2 (en) | 2004-09-17 | 2013-03-19 | Janssen Pharmaceuticals, Inc. | Pyridinone derivatives and their use as positive allosteric modulators of mGluR2-receptors |
US9266834B2 (en) | 2006-03-15 | 2016-02-23 | Janssen Pharmaceuticals, Inc. | 1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of MGLUR2-receptors |
US8841323B2 (en) | 2006-03-15 | 2014-09-23 | Janssen Pharmaceuticals, Inc. | 1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of MGLUR2-receptors |
US8906939B2 (en) | 2007-03-07 | 2014-12-09 | Janssen Pharmaceuticals, Inc. | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
US8299101B2 (en) | 2007-03-07 | 2012-10-30 | Janssen Pharmaceuticals, Inc. | 1,4-disubstituted 3-cyano-pyridone derivatives and their use as positive mGluR2-receptor modulators |
US9067891B2 (en) | 2007-03-07 | 2015-06-30 | Janssen Pharmaceuticals, Inc. | 1,4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of mGluR2-receptors |
US8252937B2 (en) | 2007-09-14 | 2012-08-28 | Janssen Pharmaceuticals, Inc. | 1,3-disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones |
US11071729B2 (en) | 2007-09-14 | 2021-07-27 | Addex Pharmaceuticals S.A. | 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones |
US9114138B2 (en) | 2007-09-14 | 2015-08-25 | Janssen Pharmaceuticals, Inc. | 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′] bipyridinyl-2′-ones |
US9132122B2 (en) | 2007-09-14 | 2015-09-15 | Janssen Pharmaceuticals, Inc. | 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones |
US8691849B2 (en) | 2008-09-02 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
US8691813B2 (en) | 2008-11-28 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
US8937060B2 (en) | 2009-05-12 | 2015-01-20 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders |
US8946205B2 (en) | 2009-05-12 | 2015-02-03 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US9085577B2 (en) | 2009-05-12 | 2015-07-21 | Janssen Pharmaceuticals, Inc. | 7-aryl-1,2,4-triazolo[4,3-A]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US9226930B2 (en) | 2009-05-12 | 2016-01-05 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders |
US9737533B2 (en) | 2009-05-12 | 2017-08-22 | Janssen Pharmaceuticals. Inc. | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders |
US10071095B2 (en) | 2009-05-12 | 2018-09-11 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of neurological and psychiatric disorders |
US9012448B2 (en) | 2010-11-08 | 2015-04-21 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
US8993591B2 (en) | 2010-11-08 | 2015-03-31 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors |
US10106542B2 (en) | 2013-06-04 | 2018-10-23 | Janssen Pharmaceutica Nv | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors |
US10584129B2 (en) | 2013-06-04 | 2020-03-10 | Janssen Pharmaceuticals Nv | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors |
US9708315B2 (en) | 2013-09-06 | 2017-07-18 | Janssen Pharmaceutica Nv | 1,2,4-triazolo[4,3-a]pyridine compounds and their use as positive allosteric modulators of MGLUR2 receptors |
US10537573B2 (en) | 2014-01-21 | 2020-01-21 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
US11103506B2 (en) | 2014-01-21 | 2021-08-31 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
US11369606B2 (en) | 2014-01-21 | 2022-06-28 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
Also Published As
Publication number | Publication date |
---|---|
DE4326758A1 (de) | 1995-02-16 |
US6043369A (en) | 2000-03-28 |
EP0713488B1 (de) | 1997-10-15 |
JPH09501167A (ja) | 1997-02-04 |
KR100317847B1 (ko) | 2002-04-24 |
DE59404361D1 (de) | 1997-11-20 |
KR960703408A (ko) | 1996-08-17 |
EP0713488A1 (de) | 1996-05-29 |
TW353072B (en) | 1999-02-21 |
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