WO1995003747A1 - Segmented pliable intrastromal corneal insert - Google Patents
Segmented pliable intrastromal corneal insert Download PDFInfo
- Publication number
- WO1995003747A1 WO1995003747A1 PCT/US1994/008458 US9408458W WO9503747A1 WO 1995003747 A1 WO1995003747 A1 WO 1995003747A1 US 9408458 W US9408458 W US 9408458W WO 9503747 A1 WO9503747 A1 WO 9503747A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- insert
- intrastromal
- cornea
- channel
- eye
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Eye Examination Apparatus (AREA)
- Electrotherapy Devices (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU75155/94A AU692172B2 (en) | 1993-08-02 | 1994-07-28 | Segmented pliable intrastromal corneal insert |
AT94925119T ATE261705T1 (en) | 1993-08-02 | 1994-07-28 | COLLAPSIBLE, INTRASTROMAL, MULTIPLE SEGMENT CORNEAL INSERT |
BR9407170A BR9407170A (en) | 1993-08-02 | 1994-07-28 | Segmented foldable intrastromal corneal insertion |
JP7505936A JPH09503680A (en) | 1993-08-02 | 1994-07-28 | Segmented supple corneal intrastromal insert |
EP94925119A EP0712297B1 (en) | 1993-08-02 | 1994-07-28 | Segmented pliable intrastromal corneal insert |
DE69433625T DE69433625T2 (en) | 1993-08-02 | 1994-07-28 | COMPATIBLE, INTRASTROMALER, CORNEAL APPLICATION OF SEVERAL SEGMENTS |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10144093A | 1993-08-02 | 1993-08-02 | |
US08/101,440 | 1993-08-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995003747A1 true WO1995003747A1 (en) | 1995-02-09 |
Family
ID=22284651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1994/008458 WO1995003747A1 (en) | 1993-08-02 | 1994-07-28 | Segmented pliable intrastromal corneal insert |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP0712297B1 (en) |
JP (2) | JPH09503680A (en) |
AT (1) | ATE261705T1 (en) |
AU (1) | AU692172B2 (en) |
BR (1) | BR9407170A (en) |
CA (1) | CA2168789A1 (en) |
DE (1) | DE69433625T2 (en) |
DK (1) | DK0712297T3 (en) |
ES (1) | ES2213748T3 (en) |
IL (1) | IL110533A (en) |
PT (1) | PT712297E (en) |
SG (2) | SG114457A1 (en) |
WO (1) | WO1995003747A1 (en) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997028759A1 (en) * | 1996-02-09 | 1997-08-14 | Kera Vision, Inc. | Segmented intrastromal corneal insert for altering corneal refractive properties and methods thereof |
WO1999030644A1 (en) | 1997-12-18 | 1999-06-24 | Keravision, Inc. | Corneal implant introducer |
WO2000025704A1 (en) * | 1998-11-04 | 2000-05-11 | Keravision, Inc. | Variable modulus corneal implant and fabrication methods |
WO2001049334A1 (en) * | 2000-01-06 | 2001-07-12 | Ferrara Ophthalmics Ltda. | Intracorneal implant, and a method of treating cornea deformities |
US6508837B1 (en) | 1993-08-02 | 2003-01-21 | Addition Technology, Inc. | Segmented pre-formed intrastromal corneal insert |
WO2005065644A2 (en) * | 2003-12-22 | 2005-07-21 | Bausch & Lomb Incorporated | Drug delivery device with mesh based suture tab |
WO2009149060A1 (en) * | 2008-06-04 | 2009-12-10 | Acufocus, Inc. | Opaque corneal insert for refractive correction |
US8864824B2 (en) | 2003-06-17 | 2014-10-21 | Acufocus, Inc. | Method and apparatus for aligning a mask with the visual axis of an eye |
US9005281B2 (en) | 2009-08-13 | 2015-04-14 | Acufocus, Inc. | Masked intraocular implants and lenses |
US9138142B2 (en) | 2003-05-28 | 2015-09-22 | Acufocus, Inc. | Masked intraocular devices |
US9204962B2 (en) | 2013-03-13 | 2015-12-08 | Acufocus, Inc. | In situ adjustable optical mask |
US9427922B2 (en) | 2013-03-14 | 2016-08-30 | Acufocus, Inc. | Process for manufacturing an intraocular lens with an embedded mask |
US9427311B2 (en) | 2009-08-13 | 2016-08-30 | Acufocus, Inc. | Corneal inlay with nutrient transport structures |
US9545303B2 (en) | 2011-12-02 | 2017-01-17 | Acufocus, Inc. | Ocular mask having selective spectral transmission |
US9943403B2 (en) | 2014-11-19 | 2018-04-17 | Acufocus, Inc. | Fracturable mask for treating presbyopia |
US10004593B2 (en) | 2009-08-13 | 2018-06-26 | Acufocus, Inc. | Intraocular lens with elastic mask |
EP3226808A4 (en) * | 2014-12-01 | 2018-07-25 | Marwan Ghabra | Intra corneal implants and methods of using same |
EP3492052A1 (en) * | 2017-11-29 | 2019-06-05 | Roberto Gustavo Albertazzi | Injector and intracorneal segment to treat corneal disorders |
CN109907861A (en) * | 2019-04-22 | 2019-06-21 | 清华大学深圳研究生院 | A kind of multifunctionality corneal graft |
US10687935B2 (en) | 2015-10-05 | 2020-06-23 | Acufocus, Inc. | Methods of molding intraocular lenses |
US11364110B2 (en) | 2018-05-09 | 2022-06-21 | Acufocus, Inc. | Intraocular implant with removable optic |
US11464625B2 (en) | 2015-11-24 | 2022-10-11 | Acufocus, Inc. | Toric small aperture intraocular lens with extended depth of focus |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0757102A1 (en) * | 1995-08-04 | 1997-02-05 | Plant Genetic Systems N.V. | Genetic transformation using a PARP inhibitor |
US8029515B2 (en) * | 2005-01-31 | 2011-10-04 | Yichieh Shiuey | Corneal implants and methods and systems for placement |
US20090240327A1 (en) | 2006-05-23 | 2009-09-24 | Albert Daxer | Corneal Implant and Method for Correction of Impaired Vision in the Human Eye |
EP2280676A2 (en) * | 2008-04-25 | 2011-02-09 | The Regents of the University of California | Device to store and inject corneal graft |
RU2525671C2 (en) * | 2012-12-04 | 2014-08-20 | Государственное бюджетное учреждение "Уфимский научно-исследовательский институт глазных болезней Академии наук Республики Башкортостан" | Method of treating extrusion of segments after implantation of intrastromal corneal segments in case of keratectasia |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4961744A (en) * | 1982-01-04 | 1990-10-09 | Keravision, Inc. | Holder for inserting corneal curvature adjustable ring |
US5098443A (en) * | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
US5290271A (en) * | 1990-05-14 | 1994-03-01 | Jernberg Gary R | Surgical implant and method for controlled release of chemotherapeutic agents |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4688570A (en) | 1981-03-09 | 1987-08-25 | The Regents Of The University Of California | Ophthalmologic surgical instrument |
US4671276A (en) | 1982-01-04 | 1987-06-09 | Kera Associates | Apparatus for corneal curvature adjustment |
US4766895A (en) | 1982-01-04 | 1988-08-30 | Kera Corneal Devices, Inc. | Apparatus for corneal curvature adjustment |
US5188125A (en) * | 1982-01-04 | 1993-02-23 | Keravision, Inc. | Method for corneal curvature adjustment |
US4452325A (en) | 1982-09-27 | 1984-06-05 | Conoco Inc. | Composite structure for cutting tools |
FR2556953B1 (en) | 1983-12-21 | 1986-05-16 | Hanna Khalil | SURGICAL APPARATUS FOR RADIATION KERATOTOMY |
AU606315B2 (en) | 1985-09-12 | 1991-02-07 | Summit Technology, Inc. | Surface erosion using lasers |
US4936825A (en) * | 1988-04-11 | 1990-06-26 | Ungerleider Bruce A | Method for reducing intraocular pressure caused by glaucoma |
US5372580A (en) * | 1990-07-12 | 1994-12-13 | University Of Miami | Gel injection adjustable keratoplasty |
US5090955A (en) | 1990-07-12 | 1992-02-25 | University Of Miami | Gel injection adjustable keratoplasty |
SG49160A1 (en) * | 1992-01-14 | 1998-05-18 | Keravision Inc | Method for corneal curvature variation |
WO1994003129A1 (en) * | 1992-08-07 | 1994-02-17 | Keravision Inc. | Hybrid intrastromal corneal ring |
-
1994
- 1994-07-28 DK DK94925119T patent/DK0712297T3/en active
- 1994-07-28 ES ES94925119T patent/ES2213748T3/en not_active Expired - Lifetime
- 1994-07-28 EP EP94925119A patent/EP0712297B1/en not_active Expired - Lifetime
- 1994-07-28 BR BR9407170A patent/BR9407170A/en not_active Application Discontinuation
- 1994-07-28 SG SG200000449A patent/SG114457A1/en unknown
- 1994-07-28 DE DE69433625T patent/DE69433625T2/en not_active Expired - Fee Related
- 1994-07-28 WO PCT/US1994/008458 patent/WO1995003747A1/en active IP Right Grant
- 1994-07-28 EP EP03029374A patent/EP1424047A2/en not_active Withdrawn
- 1994-07-28 JP JP7505936A patent/JPH09503680A/en not_active Withdrawn
- 1994-07-28 AU AU75155/94A patent/AU692172B2/en not_active Ceased
- 1994-07-28 PT PT94925119T patent/PT712297E/en unknown
- 1994-07-28 SG SG1996006953A patent/SG52622A1/en unknown
- 1994-07-28 CA CA002168789A patent/CA2168789A1/en not_active Abandoned
- 1994-07-28 AT AT94925119T patent/ATE261705T1/en not_active IP Right Cessation
- 1994-08-01 IL IL11053394A patent/IL110533A/en not_active IP Right Cessation
-
2004
- 2004-11-05 JP JP2004323027A patent/JP2005095645A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4961744A (en) * | 1982-01-04 | 1990-10-09 | Keravision, Inc. | Holder for inserting corneal curvature adjustable ring |
US5098443A (en) * | 1989-03-23 | 1992-03-24 | University Of Miami | Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents |
US5290271A (en) * | 1990-05-14 | 1994-03-01 | Jernberg Gary R | Surgical implant and method for controlled release of chemotherapeutic agents |
Cited By (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6508837B1 (en) | 1993-08-02 | 2003-01-21 | Addition Technology, Inc. | Segmented pre-formed intrastromal corneal insert |
WO1997028759A1 (en) * | 1996-02-09 | 1997-08-14 | Kera Vision, Inc. | Segmented intrastromal corneal insert for altering corneal refractive properties and methods thereof |
WO1999030644A1 (en) | 1997-12-18 | 1999-06-24 | Keravision, Inc. | Corneal implant introducer |
WO2000025704A1 (en) * | 1998-11-04 | 2000-05-11 | Keravision, Inc. | Variable modulus corneal implant and fabrication methods |
WO2001049334A1 (en) * | 2000-01-06 | 2001-07-12 | Ferrara Ophthalmics Ltda. | Intracorneal implant, and a method of treating cornea deformities |
US10869752B2 (en) | 2003-05-28 | 2020-12-22 | Acufocus, Inc. | Mask for increasing depth of focus |
US9138142B2 (en) | 2003-05-28 | 2015-09-22 | Acufocus, Inc. | Masked intraocular devices |
US8864824B2 (en) | 2003-06-17 | 2014-10-21 | Acufocus, Inc. | Method and apparatus for aligning a mask with the visual axis of an eye |
WO2005065644A2 (en) * | 2003-12-22 | 2005-07-21 | Bausch & Lomb Incorporated | Drug delivery device with mesh based suture tab |
WO2005065644A3 (en) * | 2003-12-22 | 2006-05-11 | Bausch & Lomb | Drug delivery device with mesh based suture tab |
WO2009149060A1 (en) * | 2008-06-04 | 2009-12-10 | Acufocus, Inc. | Opaque corneal insert for refractive correction |
US9492272B2 (en) | 2009-08-13 | 2016-11-15 | Acufocus, Inc. | Masked intraocular implants and lenses |
US9005281B2 (en) | 2009-08-13 | 2015-04-14 | Acufocus, Inc. | Masked intraocular implants and lenses |
US9427311B2 (en) | 2009-08-13 | 2016-08-30 | Acufocus, Inc. | Corneal inlay with nutrient transport structures |
US10449036B2 (en) | 2009-08-13 | 2019-10-22 | Acufocus, Inc. | Masked intraocular implants and lenses |
US10548717B2 (en) | 2009-08-13 | 2020-02-04 | Acufocus, Inc. | Intraocular lens with elastic mask |
US11357617B2 (en) | 2009-08-13 | 2022-06-14 | Acufocus, Inc. | Method of implanting and forming masked intraocular implants and lenses |
US10004593B2 (en) | 2009-08-13 | 2018-06-26 | Acufocus, Inc. | Intraocular lens with elastic mask |
US11311371B2 (en) | 2009-08-13 | 2022-04-26 | Acufocus, Inc. | Intraocular lens with elastic mask |
US9848979B2 (en) | 2011-12-02 | 2017-12-26 | Acufocus, Inc. | Ocular mask having selective spectral transmission |
US10765508B2 (en) | 2011-12-02 | 2020-09-08 | AcFocus, Inc. | Ocular mask having selective spectral transmission |
US9545303B2 (en) | 2011-12-02 | 2017-01-17 | Acufocus, Inc. | Ocular mask having selective spectral transmission |
US10342656B2 (en) | 2011-12-02 | 2019-07-09 | Acufocus, Inc. | Ocular mask having selective spectral transmission |
US10939995B2 (en) | 2013-03-13 | 2021-03-09 | Acufocus, Inc. | In situ adjustable optical mask |
US9603704B2 (en) | 2013-03-13 | 2017-03-28 | Acufocus, Inc. | In situ adjustable optical mask |
US9204962B2 (en) | 2013-03-13 | 2015-12-08 | Acufocus, Inc. | In situ adjustable optical mask |
US11771552B2 (en) | 2013-03-13 | 2023-10-03 | Acufocus, Inc. | In situ adjustable optical mask |
US10350058B2 (en) | 2013-03-13 | 2019-07-16 | Acufocus, Inc. | In situ adjustable optical mask |
US10583619B2 (en) | 2013-03-14 | 2020-03-10 | Acufocus, Inc. | Process for manufacturing an intraocular lens with an embedded mask |
US9844919B2 (en) | 2013-03-14 | 2017-12-19 | Acufocus, Inc. | Process for manufacturing an intraocular lens with an embedded mask |
US9427922B2 (en) | 2013-03-14 | 2016-08-30 | Acufocus, Inc. | Process for manufacturing an intraocular lens with an embedded mask |
US9573328B2 (en) | 2013-03-14 | 2017-02-21 | Acufocus, Inc. | Process for manufacturing an intraocular lens with an embedded mask |
US10183453B2 (en) | 2013-03-14 | 2019-01-22 | Acufocus, Inc. | Process for manufacturing an intraocular lens with an embedded mask |
US9943403B2 (en) | 2014-11-19 | 2018-04-17 | Acufocus, Inc. | Fracturable mask for treating presbyopia |
US10905543B2 (en) | 2014-12-01 | 2021-02-02 | Mag Optics, Ltd. | Intra corneal implants and methods of using same |
EP3226808A4 (en) * | 2014-12-01 | 2018-07-25 | Marwan Ghabra | Intra corneal implants and methods of using same |
US10687935B2 (en) | 2015-10-05 | 2020-06-23 | Acufocus, Inc. | Methods of molding intraocular lenses |
US11690707B2 (en) | 2015-10-05 | 2023-07-04 | Acufocus, Inc. | Methods of molding intraocular lenses |
US11464625B2 (en) | 2015-11-24 | 2022-10-11 | Acufocus, Inc. | Toric small aperture intraocular lens with extended depth of focus |
EP3492052A1 (en) * | 2017-11-29 | 2019-06-05 | Roberto Gustavo Albertazzi | Injector and intracorneal segment to treat corneal disorders |
US11364110B2 (en) | 2018-05-09 | 2022-06-21 | Acufocus, Inc. | Intraocular implant with removable optic |
CN109907861A (en) * | 2019-04-22 | 2019-06-21 | 清华大学深圳研究生院 | A kind of multifunctionality corneal graft |
Also Published As
Publication number | Publication date |
---|---|
SG52622A1 (en) | 1998-09-28 |
EP0712297A4 (en) | 1997-03-05 |
BR9407170A (en) | 1996-09-17 |
PT712297E (en) | 2004-08-31 |
AU692172B2 (en) | 1998-06-04 |
EP1424047A2 (en) | 2004-06-02 |
IL110533A0 (en) | 1994-11-11 |
DK0712297T3 (en) | 2004-07-12 |
EP0712297B1 (en) | 2004-03-17 |
JPH09503680A (en) | 1997-04-15 |
SG114457A1 (en) | 2005-09-28 |
DE69433625T2 (en) | 2005-02-03 |
AU7515594A (en) | 1995-02-28 |
DE69433625D1 (en) | 2004-04-22 |
CA2168789A1 (en) | 1995-02-09 |
ES2213748T3 (en) | 2004-09-01 |
EP0712297A1 (en) | 1996-05-22 |
JP2005095645A (en) | 2005-04-14 |
ATE261705T1 (en) | 2004-04-15 |
IL110533A (en) | 1999-04-11 |
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