WO1994013246A1 - Two compartment infusion bag - Google Patents

Two compartment infusion bag Download PDF

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Publication number
WO1994013246A1
WO1994013246A1 PCT/GB1993/002553 GB9302553W WO9413246A1 WO 1994013246 A1 WO1994013246 A1 WO 1994013246A1 GB 9302553 W GB9302553 W GB 9302553W WO 9413246 A1 WO9413246 A1 WO 9413246A1
Authority
WO
WIPO (PCT)
Prior art keywords
compartment
bag
liquid
bag container
dispensing
Prior art date
Application number
PCT/GB1993/002553
Other languages
French (fr)
Inventor
Francis George Richard Prior
Original Assignee
Lothian Health Board
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lothian Health Board filed Critical Lothian Health Board
Priority to JP6513962A priority Critical patent/JPH09503133A/en
Priority to AU56583/94A priority patent/AU680853B2/en
Priority to US08/454,342 priority patent/US5693040A/en
Priority to DE69321734T priority patent/DE69321734D1/en
Priority to EP94902083A priority patent/EP0674503B1/en
Publication of WO1994013246A1 publication Critical patent/WO1994013246A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers

Definitions

  • the present invention relates to a bag for use in containing a liquid and from which the liquid may be dispensed.
  • the bag is particularly directed to medical applications such as for containing a solution for intravenous or otherwise administration to a patient but not exclusively.
  • a solution or blood product to be intravenously administered or otherwise dispensed is contained in a flexible flat expandable container for containing blood, blood products and the like of the type available from for example Baxter-Travenol, which is connected to a patient by a tube and a giving set using a gravity feed to dispense the solution.
  • a flexible flat expandable container for containing blood, blood products and the like of the type available from for example Baxter-Travenol, which is connected to a patient by a tube and a giving set using a gravity feed to dispense the solution.
  • the present invention provides a bag container suitable for use in dispensing liquid at a controlled rate, which bag is supportable, in use, in a dispensing attitude and which comprises a first compartment means formed and arranged for holding a main body of liquid to be dispensed, and a second compartment means formed and arranged for holding a small portion of said liquid and disposed substantially below said first compartment means in said dispensing attitude of the bag, said first compartment means being connected to an inlet of said second compartment means by a syphon conduit means, and said second compartment means being provided with outlet means for said liquid, said second compartment means with its inlet and outlet means being formed and arranged so that syphoning can be maintained in use of the bag in said dispensing attitude thereof, whereby in use, a substantially constant head of liquid is maintained in said second compartment means during dispensing of most of said liquid held in said bag container.
  • substantially all the solution contained in the bag may be dispensed at a more or less constant rate of delivery without the need for adjustment.
  • the head in the second compartment will begin to reduce and there will then be a reduction in flow rate
  • the capacity of the second compartment should be quite small relative to that of the first compartment in order to maximise the amount of fluid held in the bag which is delivered at a substantially constant rate.
  • the ratio of size between the first compartment and second compartment may be in the region of from 60:1 to 20:1, preferably from 40:1 to 30:1.
  • said first compartment has a volume of 0.5 to 6, e.g. 0.5 to 3, litres desirably from 1 to 3, e.g. l to 2.5, litres. It will be appreciated though that other ratios and sizes may be used for particular applications.
  • the syphon conduit means may be connected and extend between said first and second compartment means in any convenient manner provided the inlet to the syphon conduit is above the outlet thereof (at the inlet to the second compartment) with said bag container in said dispensing attitude.
  • said syphon conduit means extends upwardly from said inlet thereof, proximal the base of said first compartment means, (in the dispensing attitude of the bag) to a greater or lesser extent, but advantageously up towards the upper end of said first compartment means, most desirably to a level above the maximum level of fluid in the bag in order to negate the effects of hydrostatic pressure, and then downwardly to an outlet of said syphon conduit proximal a base portion of said second compartment means, so that more or less a1.1 the liquid contained in said first compartment means may be transferred to said second compartment means, with said bag container being in said dispensing attitude.
  • said syphon conduit means is secured to a side wall of the bag container, most conveniently by being formed integrally therewith.
  • said syphon conduit means is in the form of an elongate hollow tube which may be formed and arranged inside said bag container or alternatively could extend to a greater or lesser extent outside said bag container.
  • the precise form and position of the second compartment is not critical.
  • an upper portion of the second compartment may "overlap" with or extend alongside a lower part of the first compartment.
  • said first compartment means is provided with a separate inlet means to facilitate filling of said first and second compartment means with a liquid to be dispensed.
  • said bag container is provided with connector means or the like above said first compartment means for attaching said bag container to a suitable support means for supporting said bag in said dispensing attitude.
  • a syphon should be established with a substantially full syphon tube. Priming of the syphon to fill the syphon tube may be effected by at least partly filling the first compartment via the second compartment and syphon tube. Complete filling by this route would normally be less preferred due to the relatively small capacity of the syphon tubes normally used.
  • a particular advantage of the present invention is however that, where a substantially flexible and resiliently collapsible wall second compartment is used, then priming may be simply effected by squeezing together the second compartment walls so as to expel air from the second compartment through the syphon tube into the first compartment, and liquid then being drawn back into the expanding second compartment through the syphon " tube thereby filling the latter.
  • the outlet means of said second compartment means is conveniently provided with a giving set of generally known type and description which normally comprises at least a valve means formed and arranged to regulate and control the rate at which liquid is dispensed from the bag container and usually includes an enlarged diameter portion forming a drip chamber whereby the delivery rate may conveniently be monitored in drips per minute (DPM) .
  • a giving set of generally known type and description which normally comprises at least a valve means formed and arranged to regulate and control the rate at which liquid is dispensed from the bag container and usually includes an enlarged diameter portion forming a drip chamber whereby the delivery rate may conveniently be monitored in drips per minute (DPM) .
  • the diameter of the syphon conduit means will restrict the rate at which the liquid may be dispensed from the bag and that the syphon conduit means must be capable of delivering liquid from the first compartment means to the second compartment means at a rate at least equal to the maximum rate at which liquid is required to be dispensed at from the second compartment means outlet means.
  • a syphon conduit means having an internal diameter of from 0.5 to 5 mm e.g. about 1 mm.
  • Fig. l is a side view of a bag container according to the invention, with a giving set connected thereto; and Fig. 2 is a graph comparing the delivery rates (without intervention or adjustment) for a bag according to Fig.
  • the bag container generally indicated by reference number 1
  • the bag container comprises a larger upper compartment 2 and a lower, smaller compartment 4 for holding a liquid 6 to be dispensed.
  • An elongate syphon tube 8 extends from the bottom 10 up to the top 12 of the upper compartment 2 and then bends around and returns down into the bottom 14 of the lower compartment 4. Liquid 6 contained in the upper compartment 2 is syphoned into the lower compartment 4 via the syphon tube 8, due to the differential liquid head between the two compartments 2, 4.
  • a flexible delivery tube 22 e.g. of silicone rubber which has at its distal end 23 a male liner connector 24 for connection to a hyprodermic needle 25.
  • An adjustable clamp 26 is provided on the tube 22 for regulating the rate of flow through the giving set 19. It will of course be understood that the giving set 19 itself should be “primed" prior to use to flush air out of the system in well known manner e.g. by repeatedly squeezing and releasing the flexible walls of the filter chamber 20.
  • liquid will be dispensed at a regular controlled rate. It will be seen that a substantially constant head of liquid 6 (i.e. that between the inlet 20 to the elongate syphon tube 8 at the bottom 10 of the upper compartment 2 and the outlet 28 of the elongate syphon tube 8 at the bottom 14 of the lower compartment 4) is achieved irrespective of the level 29 of liquid 6 in the upper compartment 2.
  • the bag container 1 is also provided with an inlet valve
  • the bag container l is further provided with a support loop 26 for supporting the bag 1 and its contents on a suitable support (not shown) in the dispensing attitude of the container bag.
  • the bag container may be made from any suitable flexible, transparent material which may be readily sterilized.
  • a polymeric material such as silicone rubber, polyalkane e.g. polyethylene or polypropylene, polyvinyl chloride etc.
  • Fig. 2 shows a graph of the change in drip rate of a phsyiological saline solution with time over a period of
  • the abovedescribed bag container of the present invention (2 litres capacity with 50 ml lower compartment) is compared with a conventional bag (2 litres capacity) .
  • the initial drip rate is 60 D.P.M. for both bags corresponding to a delivery rate of about 3.5 ml/min.
  • the drip rate from the bag container of the present invention stays more or less constant over time, whereas the conventional bag shows a significant drop in drip rate over time.
  • the elongate syphon tube may be formed integrally within the wall of the bag container.
  • the base 31 of the upper compartment 2 could be provided with a recess 32 into which the inlet 20 of the syphon tube 8 is extended 33 to maximise the amount of liquid 6 syphoned off from the upper compartment 2.

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Packages (AREA)
  • Bag Frames (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention provides a bag container (1) suitable for use in dispensing liquid e.g. for intravenous administration, at a controlled rate. The bag comprises a first compartment (2) for holding a main body of liquid (6) to be dispensed, and a second compartment (4) for holding a small portion of the liquid (6) and disposed substantially below the first compartment (2). The first compartment (2) is connected to the second compartment (4) by a syphon conduit (8), and the second compartment (4) is provided with an outlet (18). The second compartment (4) is formed and arranged so that syphoning can be maintained in use of the bag (1) in a dispensing attitude thereof, whereby a substantially constant head of liquid (6) is maintained in the second compartment (4) during dispensing of most of said liquid (6) held in said bag container (1).

Description

Two compartment infusion bag
The present invention relates to a bag for use in containing a liquid and from which the liquid may be dispensed. The bag is particularly directed to medical applications such as for containing a solution for intravenous or otherwise administration to a patient but not exclusively.
Conventionally a solution or blood product to be intravenously administered or otherwise dispensed is contained in a flexible flat expandable container for containing blood, blood products and the like of the type available from for example Baxter-Travenol, which is connected to a patient by a tube and a giving set using a gravity feed to dispense the solution. One of the major practical problems encountered with this type of system is that the rate of flow of solution from the bag diminishes as the amount of fluid remaining in the bag reduces and the pressure head of the solution in the bag reduces. Accordingly it is necessary for the rate of dispensing to be adjusted every now and again via the giving set to compensate for the reduction in pressure, due to the change in head of liquid.
There are commercially available electro-mechanical apparatus which dispense solutions at a more or less constant rate by pumping it at a controlled rate. Such apparatus is however cumbersome, expensive and require a power source to operate.
It is an object of the present invention to avoid or minimise one or more of the foregoing disadvantages.
The present invention provides a bag container suitable for use in dispensing liquid at a controlled rate, which bag is supportable, in use, in a dispensing attitude and which comprises a first compartment means formed and arranged for holding a main body of liquid to be dispensed, and a second compartment means formed and arranged for holding a small portion of said liquid and disposed substantially below said first compartment means in said dispensing attitude of the bag, said first compartment means being connected to an inlet of said second compartment means by a syphon conduit means, and said second compartment means being provided with outlet means for said liquid, said second compartment means with its inlet and outlet means being formed and arranged so that syphoning can be maintained in use of the bag in said dispensing attitude thereof, whereby in use, a substantially constant head of liquid is maintained in said second compartment means during dispensing of most of said liquid held in said bag container.
Thus with a bag container according to the present invention, substantially all the solution contained in the bag may be dispensed at a more or less constant rate of delivery without the need for adjustment. In this connection it will be understood that once the first compartment has been drained and/or the siphon broken, then the head in the second compartment will begin to reduce and there will then be a reduction in flow rate
(see also Example hereinbelow) . Accordingly it is desirable that the capacity of the second compartment should be quite small relative to that of the first compartment in order to maximise the amount of fluid held in the bag which is delivered at a substantially constant rate. In general the ratio of size between the first compartment and second compartment may be in the region of from 60:1 to 20:1, preferably from 40:1 to 30:1. Preferably said first compartment has a volume of 0.5 to 6, e.g. 0.5 to 3, litres desirably from 1 to 3, e.g. l to 2.5, litres. It will be appreciated though that other ratios and sizes may be used for particular applications.
The syphon conduit means may be connected and extend between said first and second compartment means in any convenient manner provided the inlet to the syphon conduit is above the outlet thereof (at the inlet to the second compartment) with said bag container in said dispensing attitude. Most preferably though said syphon conduit means extends upwardly from said inlet thereof, proximal the base of said first compartment means, (in the dispensing attitude of the bag) to a greater or lesser extent, but advantageously up towards the upper end of said first compartment means, most desirably to a level above the maximum level of fluid in the bag in order to negate the effects of hydrostatic pressure, and then downwardly to an outlet of said syphon conduit proximal a base portion of said second compartment means, so that more or less a1.1 the liquid contained in said first compartment means may be transferred to said second compartment means, with said bag container being in said dispensing attitude.
Preferably said syphon conduit means is secured to a side wall of the bag container, most conveniently by being formed integrally therewith. Advantageously said syphon conduit means is in the form of an elongate hollow tube which may be formed and arranged inside said bag container or alternatively could extend to a greater or lesser extent outside said bag container.
It will be of course be appreciated that, provided a suitable difference in head is maintained between the inlet and outlet of the siphon tube, the precise form and position of the second compartment is not critical. Thus for example an upper portion of the second compartment may "overlap" with or extend alongside a lower part of the first compartment.
Although it would in principle be possible to fill the bag via the outlet from the second compartment and the syphon tube, desirably said first compartment means is provided with a separate inlet means to facilitate filling of said first and second compartment means with a liquid to be dispensed.
Preferably said bag container is provided with connector means or the like above said first compartment means for attaching said bag container to a suitable support means for supporting said bag in said dispensing attitude.
In use of the bag it is of course necessary that a syphon should be established with a substantially full syphon tube. Priming of the syphon to fill the syphon tube may be effected by at least partly filling the first compartment via the second compartment and syphon tube. Complete filling by this route would normally be less preferred due to the relatively small capacity of the syphon tubes normally used. A particular advantage of the present invention is however that, where a substantially flexible and resiliently collapsible wall second compartment is used, then priming may be simply effected by squeezing together the second compartment walls so as to expel air from the second compartment through the syphon tube into the first compartment, and liquid then being drawn back into the expanding second compartment through the syphon "tube thereby filling the latter.
The outlet means of said second compartment means is conveniently provided with a giving set of generally known type and description which normally comprises at least a valve means formed and arranged to regulate and control the rate at which liquid is dispensed from the bag container and usually includes an enlarged diameter portion forming a drip chamber whereby the delivery rate may conveniently be monitored in drips per minute (DPM) . It is a particular advantage of the present invention though that very simple forms of giving set comprising as little as a screw clamp can be used without the need for frequent adjustment during dispensing to provide the required generally constant flow rate.
It will be understood that the diameter of the syphon conduit means will restrict the rate at which the liquid may be dispensed from the bag and that the syphon conduit means must be capable of delivering liquid from the first compartment means to the second compartment means at a rate at least equal to the maximum rate at which liquid is required to be dispensed at from the second compartment means outlet means. Desirably there is used a syphon conduit means having an internal diameter of from 0.5 to 5 mm e.g. about 1 mm.
Further preferred features and advantages of the present invention will appear from the following detailed description given by way of example of a preferred embodiment illustrated with reference to the accompanying drawing in which:-
Fig. l is a side view of a bag container according to the invention, with a giving set connected thereto; and Fig. 2 is a graph comparing the delivery rates (without intervention or adjustment) for a bag according to Fig.
1 and a conventional single compartment bag. In more detail the bag container, generally indicated by reference number 1, comprises a larger upper compartment 2 and a lower, smaller compartment 4 for holding a liquid 6 to be dispensed. An elongate syphon tube 8 extends from the bottom 10 up to the top 12 of the upper compartment 2 and then bends around and returns down into the bottom 14 of the lower compartment 4. Liquid 6 contained in the upper compartment 2 is syphoned into the lower compartment 4 via the syphon tube 8, due to the differential liquid head between the two compartments 2, 4.
At the base 15 of the second compartment 4 is provided a connector 16 with a membrane seal 17 for receiving the closure piercing device 18 of a conventional giving or administration set 19 which also optionally includes a filter 20 (for use in removing fibrin clots where the bag contains blood) and a drip chamber 21. Downstream of the drip chamber 21 is provided a flexible delivery tube 22 e.g. of silicone rubber which has at its distal end 23 a male liner connector 24 for connection to a hyprodermic needle 25. An adjustable clamp 26 is provided on the tube 22 for regulating the rate of flow through the giving set 19. It will of course be understood that the giving set 19 itself should be "primed" prior to use to flush air out of the system in well known manner e.g. by repeatedly squeezing and releasing the flexible walls of the filter chamber 20.
In use, once the clamp 26 has been opened on the delivery tube 22 of the giving set 19, liquid will be dispensed at a regular controlled rate. It will be seen that a substantially constant head of liquid 6 (i.e. that between the inlet 20 to the elongate syphon tube 8 at the bottom 10 of the upper compartment 2 and the outlet 28 of the elongate syphon tube 8 at the bottom 14 of the lower compartment 4) is achieved irrespective of the level 29 of liquid 6 in the upper compartment 2.
The bag container 1 is also provided with an inlet valve
30 in the bottom 10 of the upper compartment 2 so that the compartment 2 may be filled with liquid 6 to be dispensed. The bag container l is further provided with a support loop 26 for supporting the bag 1 and its contents on a suitable support (not shown) in the dispensing attitude of the container bag.
The bag container may be made from any suitable flexible, transparent material which may be readily sterilized. Preferably there is used a polymeric material such as silicone rubber, polyalkane e.g. polyethylene or polypropylene, polyvinyl chloride etc.
Fig. 2 shows a graph of the change in drip rate of a phsyiological saline solution with time over a period of
4 hours. For comparison the abovedescribed bag container of the present invention (2 litres capacity with 50 ml lower compartment) is compared with a conventional bag (2 litres capacity) . The initial drip rate is 60 D.P.M. for both bags corresponding to a delivery rate of about 3.5 ml/min. As will be seen from the graph the drip rate from the bag container of the present invention stays more or less constant over time, whereas the conventional bag shows a significant drop in drip rate over time.
Various modifications may be made without departing from the scope of the present invention. Thus for example, the elongate syphon tube may be formed integrally within the wall of the bag container. Also the base 31 of the upper compartment 2 could be provided with a recess 32 into which the inlet 20 of the syphon tube 8 is extended 33 to maximise the amount of liquid 6 syphoned off from the upper compartment 2.

Claims

1. A bag container suitable for use in dispensing liquid at a controlled rate, which bag is supportable, in use, in a dispensing attitude and which bag comprises a first compartment means formed and arranged for holding a main body of liquid to be dispensed, and a second compartment means formed and arranged for holding a small portion of said liquid and disposed substantially below said first compartment means in said dispensing attitude of the bag, said first compartment means being connected to an inlet of said second compartment means by a syphon conduit means, and said second compartment means being provided with outlet means for said liquid, said second compartment means with its inlet and outlet means being formed and arranged so that syphoning can be maintained in use of the bag in said dispensing attitude thereof, whereby in use, a substantially constant head of liquid is maintained in said second compartment means during dispensing of most of said liquid held in said bag container.
2. A bag container according to claim 1 wherein said second compartment has a capacity of not more than one twentieth of that of the first compartment.
3. A bag compartment according to claim l wherein the capacity of the first compartment is from 20 to 60 times the capacity of the second compartment.
3. A bag container according to claim 2 wherein said first compartment has a capacity of from 30 to 40 times that of the second compartment.
4. A bag container according to any one of claims 1 to 3 wherein said first compartment has a volume of from 0.5 to 3 litres.
5. A bag container according to any one of claims l to 5 4 wherein said second compartment is in the form of a flexible bag.
6. A bag container according to any one of claims 1 to
5 wherein said syphon conduit means extends from said inlet thereof, proximal the base of said first 0 compartment means towards the upper end of said first compartment means, and then to an outlet of said syphon conduit proximal a base portion of said second compartment means, so that more or less all the liquid contained in said first compartment means may be 5 transferred to said second compartment means, with said bag container being in said dispensing attitude.
■ fx
7. A bag container according to any one of claims l to
6 wherein said syphon conduit means is connected to a side wall of the bag container.
0 8. A bag container according to any one of the preceding claims wherein the outlet of said second compartment is connected to a giving set.
9. A bag container according to any one of the preceding claims which bag is substantially filled with 5 a physiologically acceptable fluid suitable for intravenous administration.
PCT/GB1993/002553 1992-12-16 1993-12-15 Two compartment infusion bag WO1994013246A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP6513962A JPH09503133A (en) 1992-12-16 1993-12-15 2 compartment fluid injection bag
AU56583/94A AU680853B2 (en) 1992-12-16 1993-12-15 Two compartment infusion bag
US08/454,342 US5693040A (en) 1992-12-16 1993-12-15 Two compartment infusion bag
DE69321734T DE69321734D1 (en) 1992-12-16 1993-12-15 INFUSION BAG WITH TWO CHAMBERS
EP94902083A EP0674503B1 (en) 1992-12-16 1993-12-15 Two compartment infusion bag

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929227195A GB9227195D0 (en) 1992-12-16 1992-12-16 Bag
GB9227195.6 1992-12-16

Publications (1)

Publication Number Publication Date
WO1994013246A1 true WO1994013246A1 (en) 1994-06-23

Family

ID=10727384

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1993/002553 WO1994013246A1 (en) 1992-12-16 1993-12-15 Two compartment infusion bag

Country Status (9)

Country Link
US (1) US5693040A (en)
EP (1) EP0674503B1 (en)
JP (1) JPH09503133A (en)
AT (1) ATE172374T1 (en)
AU (1) AU680853B2 (en)
CA (1) CA2151708A1 (en)
DE (1) DE69321734D1 (en)
GB (1) GB9227195D0 (en)
WO (1) WO1994013246A1 (en)

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IL123839A0 (en) * 1998-03-26 1998-10-30 Atad Dev & Medical Services Ltd Pressurized intravenous infusion bag
US6666665B1 (en) 1999-03-04 2003-12-23 Baxter International Inc. Fluid delivery mechanism having a plurality of plungers for compressing a metering chamber
US7678097B1 (en) 1999-11-12 2010-03-16 Baxter International Inc. Containers and methods for manufacturing same
US6921385B2 (en) 2002-08-05 2005-07-26 Alcon, Inc. Apparatus for delivery of fluid to opthalmic surgical handpiece
US7160268B2 (en) * 2002-08-05 2007-01-09 Alcon, Inc. Container for delivery of fluid to ophthalmic surgical handpiece
US20060093765A1 (en) * 2004-10-29 2006-05-04 Sealed Air Corporation (Us) Multi-compartment pouch having a frangible seal
US20080077116A1 (en) * 2006-09-12 2008-03-27 Rosemary Dailey Container for intravenous fluids
US20100286650A1 (en) * 2009-05-07 2010-11-11 Alan Fitzgerald Medical Fluid Container
USD1028219S1 (en) * 2022-06-15 2024-05-21 Hui Yu En Technology (Shenzhen) Co., Ltd. End-expiratory bag collection

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US3949745A (en) * 1975-08-28 1976-04-13 Howell William L Parenteral fluid administration set
US4000738A (en) * 1975-12-19 1977-01-04 Howell William L Parenteral fluid administration set (plastic-bag type)

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US2640358A (en) * 1947-12-11 1953-06-02 Sun Oil Co Sampler
US2542461A (en) * 1949-06-20 1951-02-20 Frank N Bay Automatic surgical irrigator
US2848995A (en) * 1949-07-06 1958-08-26 Abbott Lab Transfusion apparatus
US2648333A (en) * 1951-09-17 1953-08-11 Cutter Lab Drip meter
US2786467A (en) * 1955-07-01 1957-03-26 Russell W Price Apparatus for dispensing intravenous solutions
US3030952A (en) * 1956-12-24 1962-04-24 Baxter Don Inc Solution administration device and method of forming the same
US3028863A (en) * 1959-10-14 1962-04-10 Roger P Mattson Disposable enema units
SE394646B (en) * 1974-04-26 1977-07-04 Nilson B PACKAGING, SEPARATE TUBE PACKAGING, JUST MADE TO PRODUCE ONE SUCH
US4484920A (en) * 1982-04-06 1984-11-27 Baxter Travenol Laboratories, Inc. Container for mixing a liquid and a solid
US4432763A (en) * 1982-05-10 1984-02-21 The Kendall Company Fluid delivery system and method
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4576603A (en) * 1984-06-18 1986-03-18 Gerald Moss Feeding device for enterally administering liquids into a human body
DE69111480T2 (en) * 1990-02-14 1996-03-14 Shinsozai Sogo Kenkyusho Kk Filled and sealed, independent mixing container.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949745A (en) * 1975-08-28 1976-04-13 Howell William L Parenteral fluid administration set
US4000738A (en) * 1975-12-19 1977-01-04 Howell William L Parenteral fluid administration set (plastic-bag type)

Also Published As

Publication number Publication date
EP0674503A1 (en) 1995-10-04
CA2151708A1 (en) 1994-06-23
AU5658394A (en) 1994-07-04
GB9227195D0 (en) 1993-03-03
ATE172374T1 (en) 1998-11-15
DE69321734D1 (en) 1998-11-26
JPH09503133A (en) 1997-03-31
EP0674503B1 (en) 1998-10-21
US5693040A (en) 1997-12-02
AU680853B2 (en) 1997-08-14

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