WO1994010558A1 - Electrochemical sensor - Google Patents
Electrochemical sensor Download PDFInfo
- Publication number
- WO1994010558A1 WO1994010558A1 PCT/GB1993/002241 GB9302241W WO9410558A1 WO 1994010558 A1 WO1994010558 A1 WO 1994010558A1 GB 9302241 W GB9302241 W GB 9302241W WO 9410558 A1 WO9410558 A1 WO 9410558A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sensor
- test station
- electrode
- magazine
- receptacle
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
- G01N33/48757—Test elements dispensed from a stack
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00089—Magazines
Definitions
- This invention relates to an electrochemical sensor of the kind incorporating a plurality of disposable electrodes contained within a housing.
- the invention relates particularly but not exclusively to sensors wherein the electrodes incorporate an immobilised enzyme for assay of biological analytes .
- Suitable electrodes may be manufactured by absorption or deposition of palladium or platinum onto carbon particles which may subsequently be incorporated in a porous self supporting structure.
- a substrate composed of for example carbon paper or carbon cloth may be employed.
- the manufacture and properties of such electrodes is disclosed m US-A-4044193, US-A-4166143, US-A-4293396 and US-A-4476696.
- Alternative constructions of electrodes may be employed.
- the electrode surface may be plated with a mercury film.
- a mixture of enzyme, carbon and mediator species may be deposited on the electrode surface to form an enzyme electrode.
- the electrode may also incorporate a membrane containing mediator according to PCT/GB91 /01444.
- an electrochemical sensor comprises a housing and a plurality of disposable electrode elements located in the housing and arranged so that said electrode elements may be presented sequentially in use to a test station wherein the electrodes may be contacted with a specimen containing an analyte, the test station further including electrical contact means adapted to engage said electrode element to produce a signal characteristic of said analyte
- the signal may be indicative of the present, absence or concentration of the analyte.
- the sensor may include a display adapted to provide a visible, audible or other indication in response to said signal.
- a liquid crystal display may provide a visible measure of the concentration of the analyte or may indicate whether a particular threshold has been attained.
- Each electrode preferably comprises a laminar member having a working surface carrying the immobilised reagents and an impermeable substrate. Liquid applied to the working surface is supported thereon for analysis and is prevented from drainage of the electrode to contaminate an adjacent unused electrode element
- the test station preferably comprises a receptacle for a liquid specimen.
- a receptacle may incorporate an aperture communicating with the working surface of the electrode when the latter is engaged with the test station.
- the receptacle comprises a plate having said aperture for reception of a liquid specimen.
- a multiplicity of electrode elements are arranged m stacked relationship in a magazine, the first electrode element engaging said receptacle at the test station to form an impermeable seal preventing a liquid specimen from contacting the second subsequent electrode.
- the stack of electrodes is preferably biased towards the receptacle for example by means of a spring.
- the electrodes may be circular, rectangular, elliptical, polygonal or otherwise shaped.
- Means is preferably provided to ensure that the electrodes are correctly oriented with respect to the electrical contacts on the test station. This may comprise engagement of surfaces of the electrode element with corresponding formations of the housing.
- the magazine is preferably moveable within the housing, being urged in use towards the receptacle to form a liquid- proof seal.
- an ejector is provided to displace spent electrode elements from the test station
- the ejector may comprise a laminar member slidable between first position wherein an element is located at the test station and a second position wherein the element is ejected from the apparatus.
- a linearly slidable ejector may be provided.
- a rotatable configuration in the manner of a daisy wheel may be employed.
- the magazine may be closable with a removable top, for example connected to the magazine by means of a screw thread.
- the ejector is preferably arranged to disengage the top and magazine prior to ejection of the element.
- the top may be screwed from the magazine and in a second preferred embodiment the magazine may be unscrewed from the fixed top.
- An overcentre sprung arrangement may facilitate movement of the ejector between a position wherein the element is disposed in the magazine with the top seals and a second position wherein the element is deployed at the test station. Upon further actuation the ejector returns to the original position and the used element is ejected.
- the invention finds particular application in completed analysis of biological fluids, for example blood glucose, alcohol in saliva or urine analysis.
- the invention also finds use in environmental analysis, for example analysis for ammonia, chlorine, phenols and heavy metals especially lead, copper, zmc, cadmium and mercury, in river water, industrial effluent or other aqueous samples.
- Figure 1 is an exploded view of the components of a sensor in accordance with the invention.
- FIG. 1 illustrates the assembled sensor
- Figure 3 is a partially cut away detailed view of the sensor
- Figure 4 is a cross-sectional view illustrating use of the ejector arrangement.
- Figures 5 and 6 are cross-sectional views of alternative arrangements .
- the arrangement shown in Figure 1 comprises a plate 1 having a dish-like receptacle 2 communicating with the lower surface of the plate 1 by means of aperture.
- a plurality of laminar disc-like electrode elements 3 is arranged in overlying stacked relation within a tubular magazine 4. The stack of electrodes 3 is urged upwardly against the lower surface of the plate 1 by means of a first spring 5.
- FIG. 2 illustrates an example of a sensor in accordance with this invention.
- a body 10 incorporating an LED display 11 is adapted to conform to a users hand.
- the receptacle 13 is arranged to receive a liquid specimen and an ejector 12 is arranged when manually actuated to discharge a spent electrode element. Operation of the sensor is described below.
- the arrangement shown in Figure 3 includes an upper portion of the inner tube 4 including a sealing ring 15 arranged to prevent ingress of liquid into the stack of unused elements 3.
- a desiccant disc 16 disposed below the stack of elements 3 serves to maintain the latter in an anhydrous environment.
- the compression spring 5 bears against the lower surface of the desiccant disc urging the uppermost electrode element into contact with the receptacle at the test station.
- locating means 17 extending lengthwise to the stack of electrodes serves to maintain the stack in the correct orientation with respect to electrical contacts disposed on the lower surface of the plate 1.
- the electrode elements may be rectangular or otherwise shaped to prevent disorientation of them within the magazine.
- FIG. 4a a stack of electrode elements 30 and desiccant disc 27 are urged upwardly by a spring 25 into engagement with the lower surface of a plate 20 having an aperture 21 to which a liquid specimen 22 may be applied.
- the upper disc 28 of the stack is sealed at the test station by an 0 ring 29 carried by the magazine 23.
- the magazine 23 is urged bv comDression spring 26 into engagement with the lower surface of the plate 20.
- the lower surface of tne plate 20 carries electrical contacts (not shown) adapted to connect to the electrodes on the electrode element 28 at the test station Electrochemical reaction with the analyte specimen 22 produces an electrical signal and provides a visible display in conventional manner.
- Figure 4b illustrates the first stage of ejection of a spent electrode 28 from the test station.
- the magazine 23 is withdrawn against the pressure of the compression spring 26, for example by means of a manual actuator (not shown).
- An ejector 31 shown in Figure 4c may then be used to displace the element 28 from the test station. Withdrawal of the ejector 31 allows the magazine 23 to return to the position shown in Figure 4a and a fresh electrode element is available for use.
- the elements 30 may be disposed in side by side relation rather than in a stack 30.
- the elements may be mounted on a flexible support member, for example on a strip of release paper.
- the elements 30 may be supplied to the test station by a daisy wheel arrangement.
- Figure 5 shows an alternative arrangement wherein the sensor stack 31 is held within a cartridge 32 having a screw top 33 sealed with an 0 ring 34.
- the sensors are arranged to be delivered from the cartridge by turning the screw top 33. Turning the top 33 raises the top on the thread sufficiently to allow a pusher 35 to push the top electrode sensor from the stack into test position 36.
- the pusher 35 may be driven by the turning action of the screw top 33 via a pusher gear mechanism 37.
- the pusher 35 is retracted and the screw top 33 is closed by the action of a coil spring 38.
- the sensor is dispensed from the sealed cartridge automatically upon the rotation of the cap, and the cap closes, sealing the cartridge when manual pressure is released.
- Figure 6 shows a further embodiment wherein the pusher 40 is coupled with a two position spring 41 that allows the pusher to rest in either of two positions in an overcentre manner.
- the sensor cartridge for magazine 42 carries a stack of sensors 43 and a spring 44 maintains an upward pressure on the stack 43.
- the first action of the pusher 40 is to lift the cartridge top 45 from the seal 46 to a sufficient distance to allow the uppermost sensor to be pushed into the test position 47.
- the initial action of the pusher causes the body of the cartridge 42 to be lowered a sufficient distance to allow the uppermost sensor to be pushed into the test station 47.
- the cartridge top can be fixed and can become a non-disposable component of t - the apparatus, the magazine being /placable when the supply of electrode elements is exhausted.
- the electrode elements may incorporate reagents allowing enzyme assay of alcohol, glucose or other metabolites.
- immunoassay agents may be provided, for example as disclosed in EP 0424586.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93924140A EP0667956A1 (en) | 1992-11-03 | 1993-11-01 | Electrochemical sensor |
AU53745/94A AU5374594A (en) | 1992-11-03 | 1993-11-01 | Electrochemical sensor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9223016.8 | 1992-11-03 | ||
GB929223016A GB9223016D0 (en) | 1992-11-03 | 1992-11-03 | Electrochemical sensor |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1994010558A1 true WO1994010558A1 (en) | 1994-05-11 |
Family
ID=10724459
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1993/002241 WO1994010558A1 (en) | 1992-11-03 | 1993-11-01 | Electrochemical sensor |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0667956A1 (en) |
AU (1) | AU5374594A (en) |
GB (1) | GB9223016D0 (en) |
WO (1) | WO1994010558A1 (en) |
Cited By (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0621481A2 (en) * | 1993-04-23 | 1994-10-26 | Roche Diagnostics GmbH | System for analysing the contents of liquid samples |
EP0742436A2 (en) * | 1995-05-05 | 1996-11-13 | Bayer Corporation | Means of handling multiple sensors in a glucose monitoring instrument system |
WO1997029847A1 (en) * | 1996-02-13 | 1997-08-21 | Selfcare, Inc. | Improved glucose monitor and test strip containers for use in same |
US5679518A (en) * | 1994-10-27 | 1997-10-21 | Merck & Co., Inc. | Method for finding transcription activators of the NER steroid hormone receptor |
EP0812570A1 (en) * | 1996-06-11 | 1997-12-17 | Siemens-Elema AB | Arrangement for analysing body fluids |
EP0826963A2 (en) * | 1996-09-02 | 1998-03-04 | Nokia Mobile Phones Ltd. | An apparatus for taking and analysing liquid samples, such as blood samples |
US5739039A (en) * | 1989-12-04 | 1998-04-14 | Ecossensors Limited | Microelectrodes and amperometric assays |
EP0875754A1 (en) * | 1997-04-29 | 1998-11-04 | Eastman Kodak Company | Apparatus, magazine and method for electrochemical detection or measurement |
EP0885591A3 (en) * | 1997-06-19 | 1999-12-22 | Nokia Mobile Phones Ltd. | An apparatus for taking samples |
WO2002008750A1 (en) * | 2000-07-20 | 2002-01-31 | Hypoguard Limited | Test member |
WO2002008753A2 (en) * | 2000-07-20 | 2002-01-31 | Hypoguard Limited | Device for measuring analyte concentration in a fluid |
WO2002018940A2 (en) * | 2000-08-30 | 2002-03-07 | Hypoguard Limited | Device for measuring analyte concentration in a fluid |
EP1260815A2 (en) * | 2001-05-25 | 2002-11-27 | Lifescan, Inc. | Methods for automatically monitoring analyte concentration using minimally invasive devices |
WO2003042691A1 (en) * | 2001-11-14 | 2003-05-22 | Hypoguard Limited | Sensor dispensing device |
WO2003050534A1 (en) * | 2001-12-13 | 2003-06-19 | Hypoguard Limited | Test meter calibration |
WO2004063747A1 (en) * | 2003-01-14 | 2004-07-29 | Hypoguard Limited | Sensor dispensing device |
EP1480036A1 (en) * | 2002-02-28 | 2004-11-24 | ARKRAY, Inc. | Measurement instrument, measurement tool storage case and operation mechanism |
US6827899B2 (en) | 2000-08-30 | 2004-12-07 | Hypoguard Limited | Test device |
EP1494021A1 (en) * | 2002-04-05 | 2005-01-05 | ARKRAY, Inc. | Analytical appliance cartridge with retrieval mechanism, and set of the cartridge and analyzer |
EP1500925A1 (en) * | 2002-04-19 | 2005-01-26 | Matsushita Electric Industrial Co., Ltd. | Biosensor cartridge and biosensor dispensing device |
EP1347296A3 (en) * | 2002-03-18 | 2005-02-09 | Bayer Healthcare, LLC | Storage cartridge for biosensors |
US6872358B2 (en) * | 2002-01-16 | 2005-03-29 | Lifescan, Inc. | Test strip dispenser |
US6881578B2 (en) | 2002-04-02 | 2005-04-19 | Lifescan, Inc. | Analyte concentration determination meters and methods of using the same |
US6908008B2 (en) | 2001-12-21 | 2005-06-21 | Lifescan, Inc. | Test device with means for storing and dispensing diagnostic strips |
WO2006000807A1 (en) * | 2004-06-28 | 2006-01-05 | Lifescan Scotland Limited | A test strip vial with improved vial cap and method of opening |
WO2006009534A1 (en) * | 2004-06-18 | 2006-01-26 | Roche Diagnostics Gmbh | Dispenser for flattened articles such as diagnostic test strips |
US6997343B2 (en) * | 2001-11-14 | 2006-02-14 | Hypoguard Limited | Sensor dispensing device |
WO2006072034A1 (en) * | 2004-12-29 | 2006-07-06 | Lifescan Scotland Limited | Analyte test meter incorporating an improved display |
WO2006116522A1 (en) * | 2005-04-25 | 2006-11-02 | Bayer Healthcare Llc | Sensor release mechanism for a test meter |
US7138089B2 (en) | 2000-07-20 | 2006-11-21 | Hypoguard Limited | Test device for analyzing blood glucose or other analytes in bodily fluids |
US7172728B2 (en) | 2002-04-02 | 2007-02-06 | Lifescan, Inc. | Test strip containers and methods of using the same |
US7364699B2 (en) | 2003-06-18 | 2008-04-29 | Bayer Healthcare Llc | Containers for reading and handling diagnostic reagents and methods of using the same |
US7416699B2 (en) | 1998-08-14 | 2008-08-26 | The Board Of Trustees Of The Leland Stanford Junior University | Carbon nanotube devices |
EP2031389A1 (en) * | 2007-09-03 | 2009-03-04 | Airsec S.A.S. | Vial |
EP1950562A3 (en) * | 2002-04-02 | 2009-06-17 | Lifescan Scotland Limited | Integrated sample testing meter |
US7582262B2 (en) * | 2004-06-18 | 2009-09-01 | Roche Diagnostics Operations, Inc. | Dispenser for flattened articles |
US7611899B2 (en) | 2001-08-13 | 2009-11-03 | Bayer Healthcare Llc | Sensor release for a sensor dispensing instrument |
US7708702B2 (en) | 2006-01-26 | 2010-05-04 | Roche Diagnostics Operations, Inc. | Stack magazine system |
US7712610B2 (en) | 2006-10-26 | 2010-05-11 | Lifescan Scotland Limited | Sensor vial having a deformable seal |
US8101126B2 (en) | 2005-04-25 | 2012-01-24 | Bayer Healthcare Llc | Sensor release mechanism for a meter |
US20120082597A1 (en) * | 2010-09-30 | 2012-04-05 | Abbott Diabetes Care Inc. | Analyte Test Strip Dispensers and Elastomeric Caps for Sealing the Dispensers |
EP2482070A1 (en) * | 2006-11-20 | 2012-08-01 | Bayer Healthcare LLC | Test-sensor cartridge |
US8394328B2 (en) * | 2003-12-31 | 2013-03-12 | Nipro Diagnostics, Inc. | Test strip container with integrated meter having strip coding capability |
DE202012101167U1 (en) * | 2012-03-30 | 2013-07-01 | Seramun Diagnostica Gmbh | Apparatus for determining samples in a sample volume assembly and stator for the apparatus |
WO2013131934A1 (en) * | 2012-03-07 | 2013-09-12 | Sanofi-Aventis Deutschland Gmbh | A cartridge |
US8550295B2 (en) | 2010-02-22 | 2013-10-08 | Roche Diagnostics Operations, Inc. | Container for dispensing a single test strip |
US8940246B2 (en) | 2006-03-13 | 2015-01-27 | Nipro Diagnostics, Inc. | Method and apparatus for coding diagnostic meters |
US8998032B2 (en) | 2005-03-22 | 2015-04-07 | Bayer Healthcare Llc | Cartridge with a wheel for sealing the opening |
US11559810B2 (en) | 2006-03-13 | 2023-01-24 | Trividia Health, Inc. | Method and apparatus for coding diagnostic meters |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2001443A (en) * | 1977-07-22 | 1979-01-31 | Eastman Kodak Co | Testing apparatus for analysis of liquid samples |
US5030418A (en) * | 1987-09-24 | 1991-07-09 | Fuji Photo Film Co., Ltd. | Biochemical analysis apparatus |
-
1992
- 1992-11-03 GB GB929223016A patent/GB9223016D0/en active Pending
-
1993
- 1993-11-01 AU AU53745/94A patent/AU5374594A/en not_active Abandoned
- 1993-11-01 WO PCT/GB1993/002241 patent/WO1994010558A1/en not_active Application Discontinuation
- 1993-11-01 EP EP93924140A patent/EP0667956A1/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2001443A (en) * | 1977-07-22 | 1979-01-31 | Eastman Kodak Co | Testing apparatus for analysis of liquid samples |
US5030418A (en) * | 1987-09-24 | 1991-07-09 | Fuji Photo Film Co., Ltd. | Biochemical analysis apparatus |
Cited By (92)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5739039A (en) * | 1989-12-04 | 1998-04-14 | Ecossensors Limited | Microelectrodes and amperometric assays |
EP0621481A3 (en) * | 1993-04-23 | 1995-10-18 | Boehringer Mannheim Gmbh | System for analysing the contents of liquid samples. |
EP0621481A2 (en) * | 1993-04-23 | 1994-10-26 | Roche Diagnostics GmbH | System for analysing the contents of liquid samples |
US5757666A (en) * | 1993-04-23 | 1998-05-26 | Boehringer Mannheim Gmbh | System for analyzing compounds contained liquid samples |
US5679518A (en) * | 1994-10-27 | 1997-10-21 | Merck & Co., Inc. | Method for finding transcription activators of the NER steroid hormone receptor |
US5939322A (en) * | 1994-10-27 | 1999-08-17 | Merck & Co., Inc. | Human steroid receptor |
EP0742436A2 (en) * | 1995-05-05 | 1996-11-13 | Bayer Corporation | Means of handling multiple sensors in a glucose monitoring instrument system |
EP0742436A3 (en) * | 1995-05-05 | 1997-03-19 | Bayer Ag | Means of handling multiple sensors in a glucose monitoring instrument system |
WO1997029847A1 (en) * | 1996-02-13 | 1997-08-21 | Selfcare, Inc. | Improved glucose monitor and test strip containers for use in same |
EP1225448A3 (en) * | 1996-02-13 | 2002-08-28 | Inverness Medical Technology, Inc. | Improved glucose monitor and test strip containers for use in same |
EP1225448A2 (en) * | 1996-02-13 | 2002-07-24 | Inverness Medical Technology, Inc. | Improved glucose monitor and test strip containers for use in same |
EP1970123A1 (en) * | 1996-02-13 | 2008-09-17 | Diabetes Diagnostics, Inc. | Improved glucose monitor and test strip containers for use in same |
US5989917A (en) * | 1996-02-13 | 1999-11-23 | Selfcare, Inc. | Glucose monitor and test strip containers for use in same |
EP1607137A3 (en) * | 1996-02-13 | 2007-05-02 | Inverness Medical Technology, Inc. | Improved glucose monitor and test strip containers for use in same |
US5902253A (en) * | 1996-06-11 | 1999-05-11 | Siemens-Elema Ab | Apparatus for analyzing body fluids |
EP0812570A1 (en) * | 1996-06-11 | 1997-12-17 | Siemens-Elema AB | Arrangement for analysing body fluids |
EP0826963A3 (en) * | 1996-09-02 | 1998-10-07 | Nokia Mobile Phones Ltd. | An apparatus for taking and analysing liquid samples, such as blood samples |
EP0826963A2 (en) * | 1996-09-02 | 1998-03-04 | Nokia Mobile Phones Ltd. | An apparatus for taking and analysing liquid samples, such as blood samples |
EP0875754A1 (en) * | 1997-04-29 | 1998-11-04 | Eastman Kodak Company | Apparatus, magazine and method for electrochemical detection or measurement |
EP0885591A3 (en) * | 1997-06-19 | 1999-12-22 | Nokia Mobile Phones Ltd. | An apparatus for taking samples |
US7416699B2 (en) | 1998-08-14 | 2008-08-26 | The Board Of Trustees Of The Leland Stanford Junior University | Carbon nanotube devices |
WO2002008753A3 (en) * | 2000-07-20 | 2002-04-18 | Hypoguard Ltd | Device for measuring analyte concentration in a fluid |
US7138089B2 (en) | 2000-07-20 | 2006-11-21 | Hypoguard Limited | Test device for analyzing blood glucose or other analytes in bodily fluids |
WO2002008750A1 (en) * | 2000-07-20 | 2002-01-31 | Hypoguard Limited | Test member |
WO2002008753A2 (en) * | 2000-07-20 | 2002-01-31 | Hypoguard Limited | Device for measuring analyte concentration in a fluid |
GB2365123A (en) * | 2000-07-20 | 2002-02-13 | Hypoguard Ltd | Test strip |
WO2002018940A3 (en) * | 2000-08-30 | 2002-06-06 | Hypoguard Ltd | Device for measuring analyte concentration in a fluid |
US6827899B2 (en) | 2000-08-30 | 2004-12-07 | Hypoguard Limited | Test device |
WO2002018940A2 (en) * | 2000-08-30 | 2002-03-07 | Hypoguard Limited | Device for measuring analyte concentration in a fluid |
EP1260815A3 (en) * | 2001-05-25 | 2005-03-23 | Lifescan, Inc. | Methods for automatically monitoring analyte concentration using minimally invasive devices |
EP1260815A2 (en) * | 2001-05-25 | 2002-11-27 | Lifescan, Inc. | Methods for automatically monitoring analyte concentration using minimally invasive devices |
US7906336B2 (en) | 2001-08-13 | 2011-03-15 | Bayer Healthcare Llc | Sensor dispensing instrument |
US7611899B2 (en) | 2001-08-13 | 2009-11-03 | Bayer Healthcare Llc | Sensor release for a sensor dispensing instrument |
US6997343B2 (en) * | 2001-11-14 | 2006-02-14 | Hypoguard Limited | Sensor dispensing device |
WO2003042691A1 (en) * | 2001-11-14 | 2003-05-22 | Hypoguard Limited | Sensor dispensing device |
WO2003050534A1 (en) * | 2001-12-13 | 2003-06-19 | Hypoguard Limited | Test meter calibration |
US6908008B2 (en) | 2001-12-21 | 2005-06-21 | Lifescan, Inc. | Test device with means for storing and dispensing diagnostic strips |
US6872358B2 (en) * | 2002-01-16 | 2005-03-29 | Lifescan, Inc. | Test strip dispenser |
US7449148B2 (en) | 2002-02-28 | 2008-11-11 | Arkay, Inc. | Dispensing unit for measuring articles |
US7857165B2 (en) | 2002-02-28 | 2010-12-28 | Arkray, Inc. | Dispensing unit for measuring articles |
EP1480036A1 (en) * | 2002-02-28 | 2004-11-24 | ARKRAY, Inc. | Measurement instrument, measurement tool storage case and operation mechanism |
EP1480036A4 (en) * | 2002-02-28 | 2008-05-14 | Arkray Inc | Measurement instrument, measurement tool storage case and operation mechanism |
US7270247B2 (en) | 2002-03-18 | 2007-09-18 | Bayer Healthcare Llc | Storage cartridge for biosensors |
US8105536B2 (en) | 2002-03-18 | 2012-01-31 | Bayer Healthcare Llc | Method of dispensing biosensors |
US8501095B2 (en) | 2002-03-18 | 2013-08-06 | Bayer Healthcare Llc | Method of dispensing biosensors |
AU2003200811B2 (en) * | 2002-03-18 | 2009-04-23 | Bayer Healthcare, Llc | Storage Cartridge for Biosensors |
EP1347296A3 (en) * | 2002-03-18 | 2005-02-09 | Bayer Healthcare, LLC | Storage cartridge for biosensors |
US6881578B2 (en) | 2002-04-02 | 2005-04-19 | Lifescan, Inc. | Analyte concentration determination meters and methods of using the same |
US7172728B2 (en) | 2002-04-02 | 2007-02-06 | Lifescan, Inc. | Test strip containers and methods of using the same |
EP1950562A3 (en) * | 2002-04-02 | 2009-06-17 | Lifescan Scotland Limited | Integrated sample testing meter |
EP1494021A1 (en) * | 2002-04-05 | 2005-01-05 | ARKRAY, Inc. | Analytical appliance cartridge with retrieval mechanism, and set of the cartridge and analyzer |
US8052942B2 (en) * | 2002-04-05 | 2011-11-08 | Arkray, Inc. | Analytical tool cartridge with retrieval mechanism, and set of the cartridge and analyzer |
EP1494021A4 (en) * | 2002-04-05 | 2010-01-13 | Arkray Inc | Analytical appliance cartridge with retrieval mechanism, and set of the cartridge and analyzer |
EP1500925A4 (en) * | 2002-04-19 | 2012-07-11 | Panasonic Corp | Biosensor cartridge and biosensor dispensing device |
EP1500925A1 (en) * | 2002-04-19 | 2005-01-26 | Matsushita Electric Industrial Co., Ltd. | Biosensor cartridge and biosensor dispensing device |
WO2004063747A1 (en) * | 2003-01-14 | 2004-07-29 | Hypoguard Limited | Sensor dispensing device |
JP2006516328A (en) * | 2003-01-14 | 2006-06-29 | ハイポガード・リミテッド | Sensor providing device |
US7364699B2 (en) | 2003-06-18 | 2008-04-29 | Bayer Healthcare Llc | Containers for reading and handling diagnostic reagents and methods of using the same |
US8178351B2 (en) | 2003-06-18 | 2012-05-15 | Bayer Healthcare Llc | Containers for reading and handling diagnostic reagents and methods of using the same |
US7749454B2 (en) | 2003-06-18 | 2010-07-06 | Bayer Healthcare, Llc | Containers for reading and handling diagnostic reagents and methods of using the same |
US7927545B2 (en) | 2003-06-18 | 2011-04-19 | Bayer Healthcare Llc | Containers for reading and handling diagnostic reagents and methods for using the same |
US8394328B2 (en) * | 2003-12-31 | 2013-03-12 | Nipro Diagnostics, Inc. | Test strip container with integrated meter having strip coding capability |
US7582262B2 (en) * | 2004-06-18 | 2009-09-01 | Roche Diagnostics Operations, Inc. | Dispenser for flattened articles |
US7919060B2 (en) | 2004-06-18 | 2011-04-05 | Roche Diagnostics Operations, Inc. | Dispenser for flattened articles |
CN101002091B (en) * | 2004-06-18 | 2011-12-21 | 霍夫曼-拉罗奇有限公司 | Dispenser for flattened articles such as diagnostic test strips |
WO2006009534A1 (en) * | 2004-06-18 | 2006-01-26 | Roche Diagnostics Gmbh | Dispenser for flattened articles such as diagnostic test strips |
WO2006000807A1 (en) * | 2004-06-28 | 2006-01-05 | Lifescan Scotland Limited | A test strip vial with improved vial cap and method of opening |
WO2006072034A1 (en) * | 2004-12-29 | 2006-07-06 | Lifescan Scotland Limited | Analyte test meter incorporating an improved display |
US8998032B2 (en) | 2005-03-22 | 2015-04-07 | Bayer Healthcare Llc | Cartridge with a wheel for sealing the opening |
US8101126B2 (en) | 2005-04-25 | 2012-01-24 | Bayer Healthcare Llc | Sensor release mechanism for a meter |
US8545755B2 (en) | 2005-04-25 | 2013-10-01 | Bayer Healthcare Llc | Sensor release mechanism for a test meter |
US8409505B2 (en) | 2005-04-25 | 2013-04-02 | Bayer Healthcare Llc | Sensor release mechanism for a meter |
WO2006116522A1 (en) * | 2005-04-25 | 2006-11-02 | Bayer Healthcare Llc | Sensor release mechanism for a test meter |
US8197422B2 (en) | 2006-01-26 | 2012-06-12 | Roche Diagnostics Operations, Inc. | Stack magazine system |
US7708702B2 (en) | 2006-01-26 | 2010-05-04 | Roche Diagnostics Operations, Inc. | Stack magazine system |
US8801632B2 (en) | 2006-01-26 | 2014-08-12 | Roche Diagnostics Operations, Inc. | Stack magazine system |
US11559810B2 (en) | 2006-03-13 | 2023-01-24 | Trividia Health, Inc. | Method and apparatus for coding diagnostic meters |
US9623412B2 (en) | 2006-03-13 | 2017-04-18 | Trividia Health, Inc. | Method and apparatus for coding diagnostic meters |
US10814325B2 (en) | 2006-03-13 | 2020-10-27 | Trividia Health, Inc. | Method and apparatus for coding diagnostic meters |
US8940246B2 (en) | 2006-03-13 | 2015-01-27 | Nipro Diagnostics, Inc. | Method and apparatus for coding diagnostic meters |
US7712610B2 (en) | 2006-10-26 | 2010-05-11 | Lifescan Scotland Limited | Sensor vial having a deformable seal |
EP2482070A1 (en) * | 2006-11-20 | 2012-08-01 | Bayer Healthcare LLC | Test-sensor cartridge |
US8413886B2 (en) | 2006-11-20 | 2013-04-09 | Bayer Healthcare Llc | Test-sensor cartridge |
US8685346B2 (en) | 2007-09-03 | 2014-04-01 | Clariant Production (France) S.A.S. | Vial |
EP2031389A1 (en) * | 2007-09-03 | 2009-03-04 | Airsec S.A.S. | Vial |
US8550295B2 (en) | 2010-02-22 | 2013-10-08 | Roche Diagnostics Operations, Inc. | Container for dispensing a single test strip |
US20120082597A1 (en) * | 2010-09-30 | 2012-04-05 | Abbott Diabetes Care Inc. | Analyte Test Strip Dispensers and Elastomeric Caps for Sealing the Dispensers |
CN104160271A (en) * | 2012-03-07 | 2014-11-19 | 赛诺菲-安万特德国有限公司 | A cartridge |
WO2013131934A1 (en) * | 2012-03-07 | 2013-09-12 | Sanofi-Aventis Deutschland Gmbh | A cartridge |
US9237867B2 (en) | 2012-03-07 | 2016-01-19 | Sanofi-Aventis Detuschland Gmbh | Cartridge for insertion into a blood glucose meter |
DE202012101167U1 (en) * | 2012-03-30 | 2013-07-01 | Seramun Diagnostica Gmbh | Apparatus for determining samples in a sample volume assembly and stator for the apparatus |
WO2013143533A1 (en) | 2012-03-30 | 2013-10-03 | Seramun Diagnostica Gmbh | Device for identifying samples in a sample arrangement and stand for the device |
Also Published As
Publication number | Publication date |
---|---|
EP0667956A1 (en) | 1995-08-23 |
AU5374594A (en) | 1994-05-24 |
GB9223016D0 (en) | 1992-12-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1994010558A1 (en) | Electrochemical sensor | |
EP1329395B1 (en) | Test strip dispenser | |
US9134316B2 (en) | Sensor and package | |
EP1347296B1 (en) | Storage cartridge for biosensors | |
US6827899B2 (en) | Test device | |
EP1314029B1 (en) | Device for measuring analyte concentration in a fluid | |
US7172728B2 (en) | Test strip containers and methods of using the same | |
EP1362801B1 (en) | Test strip containers and methods of using the same | |
JP4709279B2 (en) | Test equipment for determination of analyte concentration | |
EP1129211B1 (en) | Electrode strips for testing small volumes | |
CA2422962A1 (en) | Analyte concentration determination meters and methods of using the same | |
WO2007133457A2 (en) | Electrochemical test sensor with reduced sample volume | |
TW201443437A (en) | Dispenser for electrochemical sensors | |
CA2447164A1 (en) | Test element analysis system | |
EP0373629A1 (en) | Test apparatus for measuring concentration of test substance in liquid | |
CN219506511U (en) | Test paper box for detection | |
US20120094369A1 (en) | Test Material, Cassette and Meter for Using the Test Material | |
JPH0249152A (en) | Diffusion limit film holding tool |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AU CA JP US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 1993924140 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1993924140 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref country code: US Ref document number: 1995 433394 Date of ref document: 19951019 Kind code of ref document: A Format of ref document f/p: F |
|
NENP | Non-entry into the national phase |
Ref country code: CA |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1993924140 Country of ref document: EP |