WO1994002141A1 - Injection and injection kit containing omeprazole and its analogs - Google Patents
Injection and injection kit containing omeprazole and its analogs Download PDFInfo
- Publication number
- WO1994002141A1 WO1994002141A1 PCT/JP1993/000998 JP9300998W WO9402141A1 WO 1994002141 A1 WO1994002141 A1 WO 1994002141A1 JP 9300998 W JP9300998 W JP 9300998W WO 9402141 A1 WO9402141 A1 WO 9402141A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- injection
- salt
- pyridyl
- benzimidazole compound
- nonaqueous solvent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
Description
Claims
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69305642T DE69305642T2 (en) | 1992-07-28 | 1993-07-15 | Injectable drug and kit containing omoprazole or related compounds |
US08/373,245 US5589491A (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
RU95104936A RU2126252C1 (en) | 1992-07-28 | 1993-07-15 | Injection preparation and a set for injection that contain omeprazol and its analogs |
SK100-95A SK279554B6 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogues |
EP93916182A EP0652751B1 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
HU9500245A HU226778B1 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
KR1019950700327A KR100258423B1 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
CA002140347A CA2140347C (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
AU45838/93A AU674015B2 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
NO950178A NO304098B1 (en) | 1992-07-28 | 1995-01-17 | Injection solution and injection kit containing 2 - [(2-pyridyl) methylsulfinyl] benzimidazole compound |
FI950379A FI113338B (en) | 1992-07-28 | 1995-01-27 | Method of Preparation of an Injection and Injection Package Containing Omeprazole and Its Analogs |
GR960403351T GR3021937T3 (en) | 1992-07-28 | 1996-12-06 | Injection and injection kit containing omeprazole and its analogs. |
HK52397A HK52397A (en) | 1992-07-28 | 1997-04-24 | Injection and injection kit containing omeprazole and its analogs |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20120392 | 1992-07-28 | ||
JP4/201203 | 1992-07-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1994002141A1 true WO1994002141A1 (en) | 1994-02-03 |
Family
ID=16437061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1993/000998 WO1994002141A1 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
Country Status (20)
Country | Link |
---|---|
US (1) | US5589491A (en) |
EP (1) | EP0652751B1 (en) |
KR (1) | KR100258423B1 (en) |
AT (1) | ATE144421T1 (en) |
AU (1) | AU674015B2 (en) |
CA (1) | CA2140347C (en) |
CZ (1) | CZ284249B6 (en) |
DE (1) | DE69305642T2 (en) |
DK (1) | DK0652751T3 (en) |
ES (1) | ES2093445T3 (en) |
FI (1) | FI113338B (en) |
GR (1) | GR3021937T3 (en) |
HK (1) | HK52397A (en) |
HU (1) | HU226778B1 (en) |
NO (1) | NO304098B1 (en) |
NZ (1) | NZ254237A (en) |
RU (1) | RU2126252C1 (en) |
SG (1) | SG52479A1 (en) |
SK (1) | SK279554B6 (en) |
WO (1) | WO1994002141A1 (en) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996017607A1 (en) * | 1993-07-17 | 1996-06-13 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Method of producing a pantoprazol lyophilisate |
US6316020B1 (en) * | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
WO2002015908A1 (en) * | 2000-08-18 | 2002-02-28 | Takeda Chemical Industries, Ltd. | Injections |
US6730685B1 (en) | 1999-10-22 | 2004-05-04 | Astrazeneca Ab | Formulation of substituted benzimidazoles |
US6780882B2 (en) | 1996-01-04 | 2004-08-24 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6780881B2 (en) | 2000-11-22 | 2004-08-24 | Altana Pharma Ag | Freeze-dried pantoprazole preparation and pantoprazole injection |
WO2005065682A2 (en) | 2003-11-05 | 2005-07-21 | Lyka Labs Limited | Rabeprazole containing formulation |
WO2007091276A2 (en) * | 2006-02-10 | 2007-08-16 | Rajasthan Antibiotic Limited | Novel crystal form of omeprazol sodium |
USRE45198E1 (en) | 1996-01-04 | 2014-10-14 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
CN104288175A (en) * | 2014-09-17 | 2015-01-21 | 大生祥(武汉)中医投资管理有限公司 | Novel benzimidazole isomer preparation and preparation method thereof |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
CN105919953A (en) * | 2016-06-27 | 2016-09-07 | 峨眉山通惠制药有限公司 | Omeprazole sodium composition for injection and production process of omeprazole sodium composition |
GB2585628A (en) * | 2019-05-08 | 2021-01-20 | Alkaloid Ad | Pharmaceutical formulation |
CN112807282A (en) * | 2021-01-13 | 2021-05-18 | 海南葫芦娃药业集团股份有限公司 | Omeprazole sodium freeze-dried powder injection and preparation method thereof |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US20020064555A1 (en) * | 2000-09-29 | 2002-05-30 | Dan Cullen | Proton pump inhibitor formulation |
US20020192299A1 (en) * | 2000-12-28 | 2002-12-19 | Rajneesh Taneja | Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination |
KR100467100B1 (en) * | 2002-03-20 | 2005-01-24 | 일양약품주식회사 | A process for preparation of injection containing 2-[(4-methoxy-3-methyl)-2-pyridinyl]methylsulfinyl-5-(1H-pyrrol-1-yl)-1H-benzimidazole or Na salt thereof |
US20030228363A1 (en) * | 2002-06-07 | 2003-12-11 | Patel Mahendra R. | Stabilized pharmaceutical compositons containing benzimidazole compounds |
US20040006109A1 (en) * | 2002-07-03 | 2004-01-08 | Rajneesh Taneja | Liquid dosage forms of non-enterically coated acid-labile drugs |
US20040082618A1 (en) * | 2002-07-03 | 2004-04-29 | Rajneesh Taneja | Liquid dosage forms of acid labile drugs |
US20040081671A1 (en) * | 2002-07-03 | 2004-04-29 | Rajneesh Taneja | Liquid dosage forms of non-enterically coated acid-labile drugs |
US20070243251A1 (en) * | 2002-12-20 | 2007-10-18 | Rajneesh Taneja | Dosage Forms Containing A PPI, NSAID, and Buffer |
US20040121004A1 (en) * | 2002-12-20 | 2004-06-24 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
AR045258A1 (en) * | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | A PHARMACEUTICAL PRODUCT FOR INJECTION |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US20070026071A1 (en) * | 2005-07-28 | 2007-02-01 | Qpharma, Llc | Magnesium salt proton pump inhibitor dosage forms |
WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0124495A2 (en) * | 1983-03-04 | 1984-11-07 | Aktiebolaget Hässle | Omeprazole salts |
EP0356143A1 (en) * | 1988-08-18 | 1990-02-28 | Takeda Chemical Industries, Ltd. | Injectable solutions |
EP0382489A2 (en) * | 1989-02-10 | 1990-08-16 | Takeda Chemical Industries, Ltd. | Use of benzimidazole derivatives as antibacterial agents |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE416649B (en) * | 1974-05-16 | 1981-01-26 | Haessle Ab | PROCEDURE FOR THE PREPARATION OF SUBSTANCES WHICH PREVENT Gastric acid secretion |
SE7804231L (en) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Gastric acid secretion |
US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
SE8300736D0 (en) * | 1983-02-11 | 1983-02-11 | Haessle Ab | NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS |
JPS6150978A (en) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | Pyridine derivative and preparation thereof |
US5049674A (en) * | 1989-12-20 | 1991-09-17 | Aktiebolaget Hassle | Therapeutically active fluoro substituted benzimidazoles |
-
1993
- 1993-07-15 HU HU9500245A patent/HU226778B1/en not_active IP Right Cessation
- 1993-07-15 RU RU95104936A patent/RU2126252C1/en not_active IP Right Cessation
- 1993-07-15 EP EP93916182A patent/EP0652751B1/en not_active Expired - Lifetime
- 1993-07-15 AT AT93916182T patent/ATE144421T1/en not_active IP Right Cessation
- 1993-07-15 DE DE69305642T patent/DE69305642T2/en not_active Expired - Fee Related
- 1993-07-15 SG SG1996005084A patent/SG52479A1/en unknown
- 1993-07-15 NZ NZ254237A patent/NZ254237A/en not_active IP Right Cessation
- 1993-07-15 KR KR1019950700327A patent/KR100258423B1/en not_active IP Right Cessation
- 1993-07-15 ES ES93916182T patent/ES2093445T3/en not_active Expired - Lifetime
- 1993-07-15 DK DK93916182.4T patent/DK0652751T3/en active
- 1993-07-15 WO PCT/JP1993/000998 patent/WO1994002141A1/en active IP Right Grant
- 1993-07-15 SK SK100-95A patent/SK279554B6/en not_active IP Right Cessation
- 1993-07-15 AU AU45838/93A patent/AU674015B2/en not_active Ceased
- 1993-07-15 CA CA002140347A patent/CA2140347C/en not_active Expired - Lifetime
- 1993-07-15 CZ CZ95217A patent/CZ284249B6/en not_active IP Right Cessation
- 1993-07-15 US US08/373,245 patent/US5589491A/en not_active Expired - Lifetime
-
1995
- 1995-01-17 NO NO950178A patent/NO304098B1/en not_active IP Right Cessation
- 1995-01-27 FI FI950379A patent/FI113338B/en active
-
1996
- 1996-12-06 GR GR960403351T patent/GR3021937T3/en unknown
-
1997
- 1997-04-24 HK HK52397A patent/HK52397A/en not_active IP Right Cessation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0124495A2 (en) * | 1983-03-04 | 1984-11-07 | Aktiebolaget Hässle | Omeprazole salts |
EP0356143A1 (en) * | 1988-08-18 | 1990-02-28 | Takeda Chemical Industries, Ltd. | Injectable solutions |
EP0382489A2 (en) * | 1989-02-10 | 1990-08-16 | Takeda Chemical Industries, Ltd. | Use of benzimidazole derivatives as antibacterial agents |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996017607A1 (en) * | 1993-07-17 | 1996-06-13 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Method of producing a pantoprazol lyophilisate |
US6780882B2 (en) | 1996-01-04 | 2004-08-24 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
USRE45198E1 (en) | 1996-01-04 | 2014-10-14 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6316020B1 (en) * | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
US6730685B1 (en) | 1999-10-22 | 2004-05-04 | Astrazeneca Ab | Formulation of substituted benzimidazoles |
BG65580B1 (en) * | 1999-10-22 | 2009-01-30 | Astrazeneca Ab | Liquid composition with substituted benzimidazoles |
US7396841B2 (en) | 2000-08-18 | 2008-07-08 | Takeda Pharmaceutical Company Limited | Injections |
WO2002015908A1 (en) * | 2000-08-18 | 2002-02-28 | Takeda Chemical Industries, Ltd. | Injections |
US6780881B2 (en) | 2000-11-22 | 2004-08-24 | Altana Pharma Ag | Freeze-dried pantoprazole preparation and pantoprazole injection |
US7351723B2 (en) | 2000-11-22 | 2008-04-01 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
US8754108B2 (en) | 2000-11-22 | 2014-06-17 | Takeda, GmbH | Freeze-dried pantoprazole preparation and pantoprazole injection |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
WO2005065682A2 (en) | 2003-11-05 | 2005-07-21 | Lyka Labs Limited | Rabeprazole containing formulation |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
WO2007091276A3 (en) * | 2006-02-10 | 2007-12-06 | Rajasthan Antibiotic Ltd | Novel crystal form of omeprazol sodium |
WO2007091276A2 (en) * | 2006-02-10 | 2007-08-16 | Rajasthan Antibiotic Limited | Novel crystal form of omeprazol sodium |
CN104288175A (en) * | 2014-09-17 | 2015-01-21 | 大生祥(武汉)中医投资管理有限公司 | Novel benzimidazole isomer preparation and preparation method thereof |
CN105919953A (en) * | 2016-06-27 | 2016-09-07 | 峨眉山通惠制药有限公司 | Omeprazole sodium composition for injection and production process of omeprazole sodium composition |
GB2585628A (en) * | 2019-05-08 | 2021-01-20 | Alkaloid Ad | Pharmaceutical formulation |
CN112807282A (en) * | 2021-01-13 | 2021-05-18 | 海南葫芦娃药业集团股份有限公司 | Omeprazole sodium freeze-dried powder injection and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
AU674015B2 (en) | 1996-12-05 |
EP0652751A1 (en) | 1995-05-17 |
FI950379A0 (en) | 1995-01-27 |
DE69305642T2 (en) | 1997-02-27 |
CZ284249B6 (en) | 1998-10-14 |
NO304098B1 (en) | 1998-10-26 |
SK10095A3 (en) | 1995-07-11 |
DK0652751T3 (en) | 1996-11-18 |
NO950178D0 (en) | 1995-01-17 |
HUT71900A (en) | 1996-02-28 |
FI113338B (en) | 2004-04-15 |
FI950379A (en) | 1995-01-27 |
HU9500245D0 (en) | 1995-03-28 |
ATE144421T1 (en) | 1996-11-15 |
NO950178L (en) | 1995-01-17 |
RU2126252C1 (en) | 1999-02-20 |
EP0652751B1 (en) | 1996-10-23 |
SK279554B6 (en) | 1998-12-02 |
HU226778B1 (en) | 2009-10-28 |
AU4583893A (en) | 1994-02-14 |
US5589491A (en) | 1996-12-31 |
KR100258423B1 (en) | 2000-07-01 |
DE69305642D1 (en) | 1996-11-28 |
CA2140347C (en) | 2001-03-27 |
HK52397A (en) | 1997-05-02 |
CZ21795A3 (en) | 1995-10-18 |
KR950702419A (en) | 1995-07-29 |
ES2093445T3 (en) | 1996-12-16 |
GR3021937T3 (en) | 1997-03-31 |
SG52479A1 (en) | 1998-09-28 |
NZ254237A (en) | 1995-12-21 |
CA2140347A1 (en) | 1994-02-03 |
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