WO1989004875A3 - Characterization and detection of sequences associated with autoimmune diseases - Google Patents
Characterization and detection of sequences associated with autoimmune diseases Download PDFInfo
- Publication number
- WO1989004875A3 WO1989004875A3 PCT/US1988/004067 US8804067W WO8904875A3 WO 1989004875 A3 WO1989004875 A3 WO 1989004875A3 US 8804067 W US8804067 W US 8804067W WO 8904875 A3 WO8904875 A3 WO 8904875A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sequences
- autoimmune diseases
- iddm
- antibodies
- dna sequences
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP89901373A EP0439458B1 (en) | 1987-11-17 | 1988-11-14 | Characterization and detection of sequences associated with autoimmune diseases |
DE3889927T DE3889927T2 (en) | 1987-11-17 | 1988-11-14 | LABELING AND DETECTION OF SEQUENCES ASSOCIATED WITH AUTOIMMUNE DISEASES. |
JP1501309A JP2877165B2 (en) | 1987-11-17 | 1988-11-14 | Characterization and detection of sequences associated with autoimmune diseases |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/121,519 US6194561B1 (en) | 1986-03-13 | 1987-11-17 | Characterization and detection of sequences associated with autoimmune diseases |
US121,519 | 1987-11-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1989004875A2 WO1989004875A2 (en) | 1989-06-01 |
WO1989004875A3 true WO1989004875A3 (en) | 1989-06-15 |
Family
ID=22397216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1988/004067 WO1989004875A2 (en) | 1987-11-17 | 1988-11-14 | Characterization and detection of sequences associated with autoimmune diseases |
Country Status (7)
Country | Link |
---|---|
US (2) | US6194561B1 (en) |
EP (1) | EP0439458B1 (en) |
JP (1) | JP2877165B2 (en) |
AT (1) | ATE106454T1 (en) |
CA (1) | CA1339098C (en) |
DE (1) | DE3889927T2 (en) |
WO (1) | WO1989004875A2 (en) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5310893A (en) * | 1986-03-31 | 1994-05-10 | Hoffmann-La Roche Inc. | Method for HLA DP typing |
US5567809A (en) * | 1986-03-13 | 1996-10-22 | Hoffmann-La Roche Inc. | Methods and reagents for HLA DRbeta DNA typing |
US5714380A (en) * | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
US5192659A (en) * | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
GB9002625D0 (en) * | 1990-02-06 | 1990-04-04 | Univ Singapore | Human leukocyte antigen typing |
DK0527199T4 (en) * | 1990-05-01 | 2000-12-04 | Univ Leland Stanford Junior | Compositions for use in a method of treating a person suffering from disseminated sclerosis |
US7294712B2 (en) * | 1990-06-04 | 2007-11-13 | Aventis Pharma S.A. | Nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses |
JP2560160B2 (en) * | 1990-08-20 | 1996-12-04 | 社団法人北里研究所 | Novel DNA nucleotide sequence and its use |
CA2075037C (en) * | 1990-12-06 | 2002-11-26 | Henry A. Erlich | Methods and reagents for hla drbeta dna typing |
AU656549B2 (en) * | 1990-12-21 | 1995-02-09 | F. Hoffmann-La Roche Ag | HLA DQbeta DNA typing |
IE920447A1 (en) * | 1991-02-12 | 1992-08-12 | Roussel Uclaf | NUCLEOTIDE SEQUENCES CODING FOR ß-CHAIN VARIABLE REGIONS OF¹HUMAN T-LYMPHOCYTE RECEPTORS, CORRESPONDING PEPTIDE SEGMENTS¹AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS |
US5976789A (en) * | 1991-07-17 | 1999-11-02 | Bio Merieux | System of probes enabling HLA-DR typing to be performed, and typing method using said probes |
FR2679252B1 (en) * | 1991-07-17 | 1993-12-10 | Bio Merieux | PROBE SYSTEM FOR HLA DR TYPING, AND TYPING METHOD USING THE SAME. |
FR2684688B1 (en) * | 1991-12-04 | 1994-03-18 | Bertin Et Cie | METHOD FOR SELECTING AT LEAST ONE MUTATION SCREEN, ITS APPLICATION TO A PROCESS FOR QUICK IDENTIFICATION OF POLYMORPHIC ALLELES AND DEVICE FOR ITS IMPLEMENTATION. |
US5763591A (en) * | 1996-03-25 | 1998-06-09 | Cedars-Sinai Medical Center | Polynucleic acid sequences that are functionally associated with the development of autoimmune disease |
FR2749308B1 (en) * | 1996-06-03 | 1998-07-24 | Bio Merieux | NUCLEOTIDE PROBES AND METHOD FOR DETERMINING THE HLA DQB1 TYPE |
WO1998037237A1 (en) * | 1997-02-21 | 1998-08-27 | Saigene Corporation | Compositions and methods for determining predisposition to insulin dependent diabetes mellitus |
US5985567A (en) * | 1997-08-15 | 1999-11-16 | Beckman Coulter, Inc. | Hybridization detection by pretreating bound single-stranded probes |
WO2000065047A1 (en) | 1999-04-26 | 2000-11-02 | Chugai Research Institute For Molecular Medicine, Inc. | Tumor suppressor genes |
KR100762444B1 (en) * | 1999-11-01 | 2007-10-04 | 시오자와 순이찌 | Probe for Diagnosing Rheumatoid Arthritis |
US7820030B2 (en) * | 2003-04-16 | 2010-10-26 | Handylab, Inc. | System and method for electrochemical detection of biological compounds |
EP1536021A1 (en) * | 2003-11-27 | 2005-06-01 | Consortium National de Recherche en Genomique (CNRG) | Method for HLA typing |
US20100086914A1 (en) * | 2008-10-03 | 2010-04-08 | Roche Molecular Systems, Inc. | High resolution, high throughput hla genotyping by clonal sequencing |
US8268561B2 (en) * | 2008-04-09 | 2012-09-18 | Pacific Northwest Research Institute | Methods for screening for genetic predisposition to type I diabetes |
US20100261189A1 (en) * | 2008-10-03 | 2010-10-14 | Roche Molecular Systems, Inc. | System and method for detection of HLA Variants |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0084796A2 (en) * | 1982-01-22 | 1983-08-03 | Cetus Corporation | HLA typing method and cDNA probes used therein |
WO1986007464A1 (en) * | 1985-06-14 | 1986-12-18 | Genetic Systems Corporation | Methods for identifying alleles associated with increased risk of diabetes |
EP0237362A1 (en) * | 1986-03-13 | 1987-09-16 | F. Hoffmann-La Roche Ag | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids and kits therefor |
WO1988002783A1 (en) * | 1986-10-16 | 1988-04-21 | Nordisk Insulinlaboratorium | A process and an agent for detection of gene structures in humans having a great tendency to develop iddm |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
US5110920A (en) | 1982-01-22 | 1992-05-05 | Cetus Corporation | HLA typing method and DNA probes used therein |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4965189A (en) | 1986-07-01 | 1990-10-23 | University Of Massachusetts Medical School | Probes for the determination of the proclivity for development of autoimmune diseases |
US5059519A (en) | 1986-07-01 | 1991-10-22 | University Of Massachusetts Medical School | Oligonucleotide probes for the determination of the proclivity for development of autoimmune diseases |
US5039606A (en) | 1987-10-29 | 1991-08-13 | Virginia Mason Research Center | Diagnostic probe for diabetes type I predisposition |
US4971902A (en) | 1987-10-30 | 1990-11-20 | Virginia Mason Research Center | Diagnostic probe for rheumatoid arthritis predisposition |
-
1987
- 1987-11-17 US US07/121,519 patent/US6194561B1/en not_active Expired - Fee Related
-
1988
- 1988-11-14 JP JP1501309A patent/JP2877165B2/en not_active Expired - Lifetime
- 1988-11-14 AT AT89901373T patent/ATE106454T1/en not_active IP Right Cessation
- 1988-11-14 DE DE3889927T patent/DE3889927T2/en not_active Expired - Lifetime
- 1988-11-14 WO PCT/US1988/004067 patent/WO1989004875A2/en active IP Right Grant
- 1988-11-14 EP EP89901373A patent/EP0439458B1/en not_active Expired - Lifetime
- 1988-11-16 CA CA000583260A patent/CA1339098C/en not_active Expired - Lifetime
-
1995
- 1995-05-23 US US08/448,021 patent/US5665548A/en not_active Expired - Lifetime
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0084796A2 (en) * | 1982-01-22 | 1983-08-03 | Cetus Corporation | HLA typing method and cDNA probes used therein |
WO1986007464A1 (en) * | 1985-06-14 | 1986-12-18 | Genetic Systems Corporation | Methods for identifying alleles associated with increased risk of diabetes |
EP0237362A1 (en) * | 1986-03-13 | 1987-09-16 | F. Hoffmann-La Roche Ag | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids and kits therefor |
WO1988002783A1 (en) * | 1986-10-16 | 1988-04-21 | Nordisk Insulinlaboratorium | A process and an agent for detection of gene structures in humans having a great tendency to develop iddm |
Non-Patent Citations (6)
Title |
---|
Human Immunology, vol. 21, 1988, Am. Soc. for Histocompatability and Immunogenetics (US) G.T. Horn et al.: "Sequence analysis of HLA class II genes from insulin-dependent diabetic individuals", pages 249-263 * |
Human Immunology, vol. 22, 1988, Am. Soc. for Histocompatability and Immunogenetics (US) S.J. Scharf et al.: "Sequence analysis of the HLA-DR beta and HLA-DQ beta loci from three Pemphigus vulgaris patients" pages 61-69 * |
Immunogetics, vol. 24, 1986 Springer-Verlag (DE) B. Owerbach et al.: "Characterization of three HLA-DR beta genes isolated from an HLA-DR 3/4 insulin-dependent diabetic patient", pages 41-46 * |
Journal of Clinical Investigation, vol. 79, April 1987 (US) B. Michelsen et al.: "Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-dq" pages 1144-1152 * |
Proceedings of the National Academy of Sciences of the USA, vol. 85, May 1988 (Washington, DC, US) S.J. Scharf et al.: "HLA class II allelic variation and susceptibility to Pemphigus vulgaris" pages 3504-3508 * |
Science, vol. 239, no. 4843, 26 February 1988 (Washington, DC, US) A.A. Sinha et al.: "A newly characterized HLA DQ beta allele associated with Pemphigus vulgaris", pages 1026-1029 * |
Also Published As
Publication number | Publication date |
---|---|
US6194561B1 (en) | 2001-02-27 |
WO1989004875A2 (en) | 1989-06-01 |
US5665548A (en) | 1997-09-09 |
CA1339098C (en) | 1997-07-29 |
DE3889927D1 (en) | 1994-07-07 |
ATE106454T1 (en) | 1994-06-15 |
JPH03501926A (en) | 1991-05-09 |
EP0439458B1 (en) | 1994-06-01 |
DE3889927T2 (en) | 1994-11-03 |
JP2877165B2 (en) | 1999-03-31 |
EP0439458A1 (en) | 1991-08-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1989004875A3 (en) | Characterization and detection of sequences associated with autoimmune diseases | |
Jacobs et al. | Insulin receptor: covalent labeling and identification of subunits. | |
Fehlmann et al. | Molecular association between major histocompatibility complex class I antigens and insulin receptors in mouse liver membranes. | |
EP0340109A3 (en) | Anti-t-cell receptor determinants as autoimmune disease treatment | |
DE60026332D1 (en) | DIAGNOSIS OF DOMESTIC SPRUE / CELIAC DISEASE WITH THE HELP OF GLIADINE PITOPENES | |
NO20001668D0 (en) | Use of a DNA fragment, as well as complementary chains, derivatives and parts thereof | |
HUP0002472A2 (en) | Isolated dendritic cell membrane protein genes | |
Silver et al. | Chemical characterization of murine Ia alloantigens determined by the iE/iC subregions of the H-2 complex. | |
EP0177814A3 (en) | Peptide antibodies and their use in detecting oncogene products | |
WO1996021020A3 (en) | Borna disease viral sequences, diagnostics and therapeutics for nervous system diseases | |
Chapman et al. | Complete amino acid sequence of the major early embryonic beta-like globin in chickens. | |
Van Schravendijk et al. | Comparative structural analysis of HLA-A3 antigens distinguishable by cytotoxic T lymphocytes: variant E1. | |
KR970706306A (en) | Peptides and pharmaceutical compositions comprising them | |
Martin et al. | Carrier‐reactive hapten‐specific cytotoxic T lymphocyte clones originate from a highly preselected T cell repertoire: implications for chemical‐induced self‐reactivity | |
CA2109961A1 (en) | Peptides for use in induction of t cell activation against hiv-1 | |
EP0378929A3 (en) | Membrane proteins and peptides of haemophilus influenzae type b | |
AU5315790A (en) | Molecules containing at least one peptide sequence carrying one or several epitopes characteristic of a protein produced by p. falciparum at the sporozoite stage and in the hepatocytes | |
Martinko et al. | Primary structure of murine major histocompatibility complex alloantigens: completion of the sequence of the amino-terminal 284 residues of H-2Kb | |
Uehara et al. | Primary structure of murine major histocompatibility alloantigens: amino acid sequence of the cyanogen bromide fragment Ia (positions 139-228) from the H-2Kb molecule | |
KR890009972A (en) | Peptides, methods of preparation thereof, their use to obtain antibodies, and the use of antibodies to inhibit PAI 1 activity in human blood | |
WO1990012807A3 (en) | Purified, highly specific antibodies against gene products including retinoblastoma and method | |
EP0482598A2 (en) | Peptide analog of human TSH receptor affective against autoimmune hyperthyroidism | |
CA2351722A1 (en) | Mast cell-specific signal transducer and cdna thereof | |
AU706774B2 (en) | Immunoreactive and immunotherapeutic molecules which interact in subjects with insulin-dependent diabetes mellitus (IDDM) | |
De Simone et al. | Single-step purification of class 5 outer membrane protein from Neisseria meningitidis using preparative electrophoresis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): DK FI JP NO |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): AT BE CH DE FR GB IT LU NL SE |
|
AK | Designated states |
Kind code of ref document: A3 Designated state(s): DK FI JP NO |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): AT BE CH DE FR GB IT LU NL SE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1989901373 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1989901373 Country of ref document: EP |
|
WWG | Wipo information: grant in national office |
Ref document number: 1989901373 Country of ref document: EP |