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WO1985000292A1 - Fluid delivery apparatus - Google Patents

Fluid delivery apparatus

Info

Publication number
WO1985000292A1
WO1985000292A1 PCT/GB1984/000249 GB8400249W WO8500292A1 WO 1985000292 A1 WO1985000292 A1 WO 1985000292A1 GB 8400249 W GB8400249 W GB 8400249W WO 8500292 A1 WO8500292 A1 WO 8500292A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
container
fluid
device
information
memory
Prior art date
Application number
PCT/GB1984/000249
Other languages
French (fr)
Inventor
Ronald Alan Coffee
Peter Charles Bennett
Leonard Eric Houghton
Graham Charles Johnson
Original Assignee
Imperial Chemical Industries Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M5/1684Monitoring, detecting, signalling or eliminating infusion flow anomalies by detecting the amount of infusate remaining, e.g. signalling end of infusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor

Abstract

Apparatus for supplying a patient with a fluid from a container (1) having a memory device (2) associated therewith. The memory device contains information relating to the contents of the container, such as the nature of the contents and the volume remaining within the container. Means (6) are provided for monitoring a body parameter indicative of the patient's condition and further means are provided for storing information defining the rate of flow of various fluids required for various body conditions. A processor reads the information contained in the memory device and the stored information actuates a flow control device (4) associated with the container in accordance with signals supplied by the monitoring means.

Description

FLUID DELIVERY APPARATUS

This invention relates to fluid delivery apparatus and in particular to apparatus for delivery of a fluid to a patient, eg. in the course of treatment. Examples of such fluids include blood, plasma, saline solutions, drug formulations, insulin, stimulants, and anaesthetics.

It is often desirable to control the flow of fluid to the patient in response to some parameter indicative of the patient's condition: examples of such parameters include respiration rate, pulse, blood pressure, brain activity, temperature, and the composition of a body fluid eg. exhaled breath, urine, or blood.

However, there is often a risk of error; for example supply of the wrong fluid to the patient and/or supply of the wrong quantity of fluid and/or supply at the wrong rate. This risk may be compounded by possible variation in the nature of the fluid eg. differing blood groups, drug formulations of differing concentrations and the like.

We have devised apparatus whereby such risks can be minimised.

Accordingly the present invention provides apparatus for supplying a patient with a fluid comprising means for monitoring a parameter indicative of the patient's body condition, a container having a memory device associated therewith, the memory device containing information relating to the contents of the container, means for connection to said container for delivery of fluid from said container to the patient, flow control means for controlling the flow of fluid from said container to said patient, and means for reading the information stored in the memory device, whereby the flow control means can be operated in accordance with the read information and the signal derived from the monitoring means. It is seen that an important feature of the invention is the provision of an information carrying memory device associated with, and preferably attached to, the container. This memory device is coded with information relating to the contents of the container. Such containers are described in our European Patent Application No. 83300035 (Publication No. 00086029), the disclosure of which is incorporated herein by reference. The memory device is preferably an active electronic memory device, preferably digital, eg. a micro-chip, such as a PROM.

The flow control means may be a simple on/off valve or may be a proportional valve whose setting is determined by the monitored parameter in conjunction with the information carried by the memory device. The flow control means may be incorporated in the container or, alternatively, may be incorporated in the means for connection to the container for delivering the fluid to the patient.

The invention will now be described, by way of example, with reference to the accompanying drawings, in which:- Figure 1 is a diagrammatic representation of an apparatus according to the invention; and

Figure 2 is an axial section of a container fitted with a memory device and a connector to the fluid delivery means. In Figure 1 there is shown a container 1 having a memory device 2 associated therewith. The type of information that may be carried by the memory device 2 includes not only the precise nature of the fluid within the container 1, but also the optimum delivery rate for a given value of a relevant body parameter. Also a security code may be provided so that delivery of the fluid can only take place when the relevant body parameter is being monitored and has a value within a particular range. The memory device 2 may also carry information regarding the amount of fluid remaining within the container 1 so that a warning signal can be given when the container approaches exhaustion of its contents.

An outlet port 3 of container 1 is connected to a fluid flow control device 4 for delivering fluid to a patient (not shown) via a line 5. A monitor 6 is provided to monitor one or more relevant body parameters of the patient. The memory device 2 is read by a control unit 7 which also receives signals from the monitor 6. The unit 7 contains a processor which operates in accordance with a program stored therein. Associated with the processor is a store for information defining the flow rates of various fluids required by patients according to age and other factors and according to the existing value of the body parameter, as monitored by the monitor 6. In response to the information read from the memory device 2 indicating the precise nature of the fluid in container 1 and optimum delivery rates for any given value of a relevant monitored body parameter, the information stored in the processor of the unit 7, and the signals from monitor 6, the unit 7 supplies actuating signals to the fluid flow control device 4 to vary, as appropriate, the fluid delivered to the patient.

In Figure 2 the container 209 is shown inverted, having a cap 229 which is of a resilient plastic material which can sealingly grip the edge 223 of the container opening. The cap is fitted with an outlet port 234 and a vent inlet 235. Inside the supply outlet 234 is a shaped sealed ring 236, formed of rubber or like material. A sealing plate 237 is urged against sealing ring 236 by compression spring 239 the other end of which abuts a circumferential flange 240 within the upper end of outlet 234. Secured inside the vent inlet 235 and extending toward the upper end of the container 209 is an elongate duct 241, at the inner end of which is a springloaded ball valve 242, sealing the duct 241 against leakage of fluid from within container 209, but permitting air to enter container 209 when the pressure differential is sufficient to overcome the spring-loading of ball valve 242. The cap 229 also carries a memory device in the form of a pre-coded microcircuit chip 214 mounted to communicate via external conductive socket connections 243. The outer edge of cap 229 carries a thread 247, and for transport and storage carries a protective threaded cap lid (not shown). The container 209 is mounted on the system via the connector 230, shown immediately below it. This comprises a cover member 244 formed with a flanged edge 245 supporting a freely rotatable threaded collar 246 which can engage with thread 247 to hold cover member 244 and cap 229 tightly together. Cover member

244 is formed with a projecting supply pipe 248 to mate with outlet 234, a projecting vent pipe 249 to mate with vent outlet 235 and female electrical contacts 251 to mate with male sockets 243. Connections 215 from contacts 251 lead to the memory reading device. Pipe 248 projects to a height sufficient so that, when cap 229 and cover 244 are in close contact, sealing plate 237 is lifted off sealing ring 236 so the fluid can flow out around the edges of plate 237 (which for this purpose are preferably partly cut away) into pipe 248. It will be appreciated that the apparatus described with reference to Figure 1 can be modified by removing the store associated with the processor unit 7 and the connection between the unit 7 and the fluid control device 4. In this event, the unit 7 is provided with a display for information regarding the amount of fluid remaining in the container 1, derived from the memory device 2, and for the value of the body parameter, derived from the monitor 6. A doctor or nurse then manually adjusts the flow control device 6 in accordance with known information relating to the flow rate required and the patient's body condition.

Claims

1. Apparatus for supplying a patient with a fluid comprising means for monitoring a parameter indicative of the patient's body condition, a container having a memory device associated therewith, the memory device containing information relating to the contents of the container, means for connection to said container for delivery of fluid from said container to the patient, flow control means for controlling the flow of fluid drom said container to said patient, and means for reading the information stored in the memory device, whereby the flow control means can be operated in accordance with the read information and the signal derived from the monitoring means.
2. Apparatus as claimed in claim 1, further comprising means for storing information defining the flow rates required for various body conditions, the reading means being adapted further to read the information stored in the storage means and to actuate the flow control means in accordance with the information stored in the memory device and the storage means and the signal derived from the monitoring means.
3. Apparatus as claimed in claim 2, wherein the means for reading information and actuating the flow control means comprise a processing unit adapted to operate in accordance with a program stored in a memory thereof.
4. Apparatus as claimed in any one of the preceding claims, wherein the information stored in the memory device comprises data representing the nature of the fluid within the container and the optimum delivery rate for a given value of the body parameter.
5. Apparatus as claimed in any one of the preceding claims, wherein the information stored in the memory device comprises data forming a security code, whereby delivery of fluid is only allowed when the relevant body parameter is being monitored and has a value within a predetermined range.
6. Apparatus as claimed in any one of the preceding claims, wherein the information stored in the memory device comprises information regarding the amount of fluid remaining within the container, whereby a warning signal is given when the container approaches exhaustion of the contents thereof.
7. Apparatus for supplying a patient with a fluid, the apparatus being constructed, arranged and adapted to operate substantially as hereinbefore described with reference to, and as illustrated in, the accompanying drawings.
PCT/GB1984/000249 1983-07-11 1984-07-10 Fluid delivery apparatus WO1985000292A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB8318670 1983-07-11
GB8318670A GB8318670D0 (en) 1983-07-11 1983-07-11 Fluid delivery apparatus

Publications (1)

Publication Number Publication Date
WO1985000292A1 true true WO1985000292A1 (en) 1985-01-31

Family

ID=10545531

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1984/000249 WO1985000292A1 (en) 1983-07-11 1984-07-10 Fluid delivery apparatus

Country Status (4)

Country Link
EP (1) EP0149653A1 (en)
JP (1) JPS60501790A (en)
GB (1) GB8318670D0 (en)
WO (1) WO1985000292A1 (en)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0337924A2 (en) * 1988-04-13 1989-10-18 Mic Medical Instrument Corporation Device for the biofeedback control of body parameters
EP0692766A1 (en) * 1994-07-12 1996-01-17 Medrad, Inc. Closed loop information path for medical fluid delivery systems
US5806519A (en) * 1993-10-28 1998-09-15 Medrad, Inc. Total system for contrast delivery
US5840026A (en) * 1994-09-21 1998-11-24 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US5843037A (en) * 1993-10-28 1998-12-01 Medrad Inc. Multipatient fluid dispensing
US5997502A (en) * 1992-08-17 1999-12-07 Medrad, Inc. Front loading medical injector and syringe for use therewith
EP1249606A1 (en) * 2001-04-10 2002-10-16 Precimedix S.A. Medical infusion pump with programmable pump fluid cassette
US6973435B1 (en) * 1999-07-13 2005-12-06 Sioufi Habib A Method and system for ordering services or products, including prescriptions
US8197437B2 (en) 2004-11-16 2012-06-12 Medrad, Inc. Systems and methods of modeling pharmaceutical propagation in a patient
US8315449B2 (en) 2008-06-24 2012-11-20 Medrad, Inc. Identification of regions of interest and extraction of time value curves in imaging procedures
US8428694B2 (en) 2007-07-17 2013-04-23 Medrad, Inc. Methods for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
US8574200B2 (en) 2002-05-30 2013-11-05 Medrad, Inc. Dual syringe injector system
US8608484B2 (en) 2008-03-04 2013-12-17 Medrad, Inc. Dynamic anthropomorphic cardiovascular phantom
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9238099B2 (en) 2004-11-24 2016-01-19 Bayer Healthcare Llc System and apparatus for modeling pressures generated during an injection procedure
US9302044B2 (en) 2006-12-29 2016-04-05 Bayer Healthcare Llc Patient-based parameter generation systems for medical injection procedures
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US9636452B2 (en) 2000-02-07 2017-05-02 Bayer Healthcare Llc Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US9700672B2 (en) 2011-09-21 2017-07-11 Bayer Healthcare Llc Continuous multi-fluid pump device, drive and actuating system and method
US9744305B2 (en) 2012-09-28 2017-08-29 Bayer Healthcare Llc Quick release plunger
US9844622B2 (en) 2000-07-10 2017-12-19 Bayer Healthcare Llc Syringes for medical injector systems
US9855390B2 (en) 2006-03-15 2018-01-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104582596A (en) * 2012-07-10 2015-04-29 贝克顿迪金森法国两合公司 Integrated injection system and a communication device

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390238A (en) * 1966-05-13 1968-06-25 Clyde W. O'neill Intravenous fluid level signalling apparatus
BE832256A (en) * 1974-01-25 1975-12-01 automatic electronic device for performing assays volumetrically or mixtures for medical purposes
FR2350107A1 (en) * 1976-05-07 1977-12-02 Miles Lab Apparatus for adjustment of the concentration of glucose in the blood
US4078562A (en) * 1976-08-16 1978-03-14 Diana W. Friedman Infusion pump with feedback control
US4291692A (en) * 1979-10-09 1981-09-29 University Of Utah Closed-loop infusion system, both method and apparatus, based on real time urine measurement
EP0058472A1 (en) * 1981-02-12 1982-08-25 Imperial Chemical Industries Plc Agricultural spraying apparatus and containers for use therewith
WO1982003554A1 (en) * 1981-04-15 1982-10-28 Dean L Kamen Fluid flow control system
EP0086029A1 (en) * 1982-02-05 1983-08-17 Imperial Chemical Industries Plc Fluid container

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3390238A (en) * 1966-05-13 1968-06-25 Clyde W. O'neill Intravenous fluid level signalling apparatus
BE832256A (en) * 1974-01-25 1975-12-01 automatic electronic device for performing assays volumetrically or mixtures for medical purposes
FR2350107A1 (en) * 1976-05-07 1977-12-02 Miles Lab Apparatus for adjustment of the concentration of glucose in the blood
US4078562A (en) * 1976-08-16 1978-03-14 Diana W. Friedman Infusion pump with feedback control
US4291692A (en) * 1979-10-09 1981-09-29 University Of Utah Closed-loop infusion system, both method and apparatus, based on real time urine measurement
EP0058472A1 (en) * 1981-02-12 1982-08-25 Imperial Chemical Industries Plc Agricultural spraying apparatus and containers for use therewith
WO1982003554A1 (en) * 1981-04-15 1982-10-28 Dean L Kamen Fluid flow control system
EP0086029A1 (en) * 1982-02-05 1983-08-17 Imperial Chemical Industries Plc Fluid container

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0337924A3 (en) * 1988-04-13 1990-05-09 Mic Medical Instrument Corporation Device for the biofeedback control of body parameters
US5002055A (en) * 1988-04-13 1991-03-26 Mic Medical Instruments Corporation Apparatus for the biofeedback control of body functions
EP0337924A2 (en) * 1988-04-13 1989-10-18 Mic Medical Instrument Corporation Device for the biofeedback control of body parameters
US6090064A (en) * 1992-08-17 2000-07-18 Medrad, Inc. Front loading medical injector and syringe for use therewith
US5997502A (en) * 1992-08-17 1999-12-07 Medrad, Inc. Front loading medical injector and syringe for use therewith
US5806519A (en) * 1993-10-28 1998-09-15 Medrad, Inc. Total system for contrast delivery
US6149627A (en) * 1993-10-28 2000-11-21 Medrad, Inc. Multi-patient fluid dispensing
US5843037A (en) * 1993-10-28 1998-12-01 Medrad Inc. Multipatient fluid dispensing
US5739508A (en) * 1994-07-12 1998-04-14 Medrad, Inc. Closed loop information path for medical fluid delivery systems
EP0692766A1 (en) * 1994-07-12 1996-01-17 Medrad, Inc. Closed loop information path for medical fluid delivery systems
US5920054A (en) * 1994-07-12 1999-07-06 Medrad, Inc. Closed loop information path for medical fluid delivery systems
US5840026A (en) * 1994-09-21 1998-11-24 Medrad, Inc. Patient specific dosing contrast delivery systems and methods
US6973435B1 (en) * 1999-07-13 2005-12-06 Sioufi Habib A Method and system for ordering services or products, including prescriptions
US9636452B2 (en) 2000-02-07 2017-05-02 Bayer Healthcare Llc Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US9844622B2 (en) 2000-07-10 2017-12-19 Bayer Healthcare Llc Syringes for medical injector systems
EP1249606A1 (en) * 2001-04-10 2002-10-16 Precimedix S.A. Medical infusion pump with programmable pump fluid cassette
WO2002081919A1 (en) * 2001-04-10 2002-10-17 Precimedix S.A. Programmable cassette pump for injecting medicaments
US8574200B2 (en) 2002-05-30 2013-11-05 Medrad, Inc. Dual syringe injector system
US8295914B2 (en) 2004-11-16 2012-10-23 Medrad, Inc. Systems and methods of determining patient transfer functions and modeling patient response to a pharmaceutical injection
US8197437B2 (en) 2004-11-16 2012-06-12 Medrad, Inc. Systems and methods of modeling pharmaceutical propagation in a patient
US9616166B2 (en) 2004-11-16 2017-04-11 Bayer Healthcare Llc Systems and methods of determining injection protocols for diagnostic imaging procedures
US8346342B2 (en) 2004-11-16 2013-01-01 Medrad, Inc. Systems and methods of determining patient physiological parameters from an imaging procedure
US9238099B2 (en) 2004-11-24 2016-01-19 Bayer Healthcare Llc System and apparatus for modeling pressures generated during an injection procedure
US9855390B2 (en) 2006-03-15 2018-01-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes
US9302044B2 (en) 2006-12-29 2016-04-05 Bayer Healthcare Llc Patient-based parameter generation systems for medical injection procedures
US9008759B2 (en) 2007-07-17 2015-04-14 Bayer Medical Care Inc. Devices and systems for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
US8428694B2 (en) 2007-07-17 2013-04-23 Medrad, Inc. Methods for determination of parameters for a procedure, for estimation of cardiopulmonary function and for fluid delivery
US8608484B2 (en) 2008-03-04 2013-12-17 Medrad, Inc. Dynamic anthropomorphic cardiovascular phantom
US8315449B2 (en) 2008-06-24 2012-11-20 Medrad, Inc. Identification of regions of interest and extraction of time value curves in imaging procedures
US8699770B2 (en) 2008-06-24 2014-04-15 Bayer Medical Care Inc. Identification of regions of interest and extraction of time value curves in imaging procedures
US9421330B2 (en) 2008-11-03 2016-08-23 Bayer Healthcare Llc Mitigation of contrast-induced nephropathy
US9463335B2 (en) 2010-06-04 2016-10-11 Bayer Healthcare Llc System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9700672B2 (en) 2011-09-21 2017-07-11 Bayer Healthcare Llc Continuous multi-fluid pump device, drive and actuating system and method
US9744305B2 (en) 2012-09-28 2017-08-29 Bayer Healthcare Llc Quick release plunger
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector

Also Published As

Publication number Publication date Type
GB8318670D0 (en) 1983-08-10 grant
EP0149653A1 (en) 1985-07-31 application
JPS60501790A (en) 1985-10-24 application

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