UY31041A1 - Combinacion de antagonista del receptor de progesterona con antiestrogenos no esteroidales para usar en enfermedades mediadas por brca - Google Patents

Combinacion de antagonista del receptor de progesterona con antiestrogenos no esteroidales para usar en enfermedades mediadas por brca

Info

Publication number
UY31041A1
UY31041A1 UY31041A UY31041A UY31041A1 UY 31041 A1 UY31041 A1 UY 31041A1 UY 31041 A UY31041 A UY 31041A UY 31041 A UY31041 A UY 31041A UY 31041 A1 UY31041 A1 UY 31041A1
Authority
UY
Uruguay
Prior art keywords
combination
antiestrogens
diseases
brca
steroid
Prior art date
Application number
UY31041A
Other languages
English (en)
Inventor
Daniel Korr
Jens Hoffmann
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39495863&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY31041(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of UY31041A1 publication Critical patent/UY31041A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Combinacion del antagonista del receptor de progesterona 11B-(4-acetilfenil)-17B-hidroxi-17a-(1,1,2,2,2-pentafluoroetil)-estra-4,9-dien-3-ona, o un derivado o un análogo de éste aceptable para uso farmacéutico, con al menos un antiestrogeno no esteroidal, y uso de dicha combinacion para la profilaxis y el tratamiento de enfermedades mediadas por BRCA1 o BRCA2. Los antiestrogenos no esteroidales que pueden combinarse con el antagonista del receptor de progesterona 11B-(4-acetilfenil)-17B-hidroxi-17a-(1,1,2,2,2-pentafluoroetil)-estra-4,9-dien-3-ona son, por ejemplo, tamoxifeno, raloxifeno, droloxifeno, toremifeno, lasofoxifeno, arzoxifeno, GW5638, EM-800, idoxifeno y basedoxifeno.
UY31041A 2007-04-23 2008-04-22 Combinacion de antagonista del receptor de progesterona con antiestrogenos no esteroidales para usar en enfermedades mediadas por brca UY31041A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07090082 2007-04-23
US91438507P 2007-04-27 2007-04-27

Publications (1)

Publication Number Publication Date
UY31041A1 true UY31041A1 (es) 2008-11-28

Family

ID=39495863

Family Applications (1)

Application Number Title Priority Date Filing Date
UY31041A UY31041A1 (es) 2007-04-23 2008-04-22 Combinacion de antagonista del receptor de progesterona con antiestrogenos no esteroidales para usar en enfermedades mediadas por brca

Country Status (10)

Country Link
US (1) US20080268041A1 (es)
EP (1) EP2148680A1 (es)
JP (1) JP2010524998A (es)
AR (1) AR066231A1 (es)
CA (1) CA2684084A1 (es)
CL (1) CL2008001147A1 (es)
PE (1) PE20090734A1 (es)
TW (1) TW200904450A (es)
UY (1) UY31041A1 (es)
WO (1) WO2008128792A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3205648A1 (en) 2010-06-10 2017-08-16 Seragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
EA029559B1 (ru) 2011-12-14 2018-04-30 Серагон Фармасьютикалс, Инк. Фторированные модуляторы рецепторов эстрогенов и их применение

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
ATE310522T1 (de) * 2000-10-18 2005-12-15 Schering Ag Verwendung von antiprogestinen zur prophylaxe und behandlung von hormonabhängigen erkrankungen
NZ538347A (en) * 2000-10-18 2007-03-30 Schering Ag Use of antiprogestins for the induction of apoptosis in a cell
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases

Also Published As

Publication number Publication date
CA2684084A1 (en) 2008-10-30
AR066231A1 (es) 2009-08-05
EP2148680A1 (en) 2010-02-03
CL2008001147A1 (es) 2008-11-03
TW200904450A (en) 2009-02-01
US20080268041A1 (en) 2008-10-30
WO2008128792A1 (en) 2008-10-30
JP2010524998A (ja) 2010-07-22
PE20090734A1 (es) 2009-07-23

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20171005