US8592432B2 - Compounds and compositions as protein kinase inhibitors - Google Patents

Compounds and compositions as protein kinase inhibitors Download PDF

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Publication number
US8592432B2
US8592432B2 US12/936,199 US93619909A US8592432B2 US 8592432 B2 US8592432 B2 US 8592432B2 US 93619909 A US93619909 A US 93619909A US 8592432 B2 US8592432 B2 US 8592432B2
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United States
Prior art keywords
methyl
isopropoxy
alkyl
phenyl
isopropylsulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related, expires
Application number
US12/936,199
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US20110135668A1 (en
Inventor
Bei Chen
Tao Jiang
Thomas H. Marsilje
Pierre-Yves Michellys
Truc Ngoc Nguyen
Wei Pei
Baogen Wu
Zhaobo Gao
Yonghui Ge
Chen Huang
Yuncheng Li
Xuefeng Zhu
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Novartis AG
Original Assignee
IRM LLC
Novartis AG
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Publication date
Priority to US4311108P priority Critical
Priority to US11602308P priority
Priority to PCT/US2009/039383 priority patent/WO2009126515A1/en
Priority to US12/936,199 priority patent/US8592432B2/en
Application filed by IRM LLC, Novartis AG filed Critical IRM LLC
Assigned to SUZHOU NOVARTIS PHARMA TECHNOLOGY CO., LTD. reassignment SUZHOU NOVARTIS PHARMA TECHNOLOGY CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: GAO, ZHAOBO, GE, YONGHUI, HUANG, CHEN, LI, YUNCHENG
Assigned to NOVARTIS AG reassignment NOVARTIS AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SUZHOU NOVARTIS PHARMA TECHNOLOGY CO., LTD.
Assigned to IRM LLC reassignment IRM LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MICHELLYS, PIERRE-YVES, CHEN, BEI, JIANG, TAO, NGUYEN, TRUC NGOC, WU, BAOGEN, MARSILJE, THOMAS H., III
Assigned to IRM LLC reassignment IRM LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MARSILJE, THOMAS H., III, CHEN, BEI, PEI, WEI, WU, BAOGEN, JIANG, TAO, NGUYEN, TRUC NGOC, ZHU, XUEFENG, MICHELLYS, PIERRE-YVES
Publication of US20110135668A1 publication Critical patent/US20110135668A1/en
Application granted granted Critical
Publication of US8592432B2 publication Critical patent/US8592432B2/en
Assigned to NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. reassignment NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: IRM LLC
Assigned to NOVARTIS AG reassignment NOVARTIS AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.
Expired - Fee Related legal-status Critical Current
Adjusted expiration legal-status Critical

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