US781880A - Product from bone. - Google Patents

Product from bone. Download PDF

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Publication number
US781880A
US781880A US21461804A US1904214618A US781880A US 781880 A US781880 A US 781880A US 21461804 A US21461804 A US 21461804A US 1904214618 A US1904214618 A US 1904214618A US 781880 A US781880 A US 781880A
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US
United States
Prior art keywords
bone
product
fiber
lime
matter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US21461804A
Inventor
Joseph Ross Hunter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WILLIAM HINCKLE SMITH
Original Assignee
WILLIAM HINCKLE SMITH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WILLIAM HINCKLE SMITH filed Critical WILLIAM HINCKLE SMITH
Priority to US21461804A priority Critical patent/US781880A/en
Application granted granted Critical
Publication of US781880A publication Critical patent/US781880A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/84Bones; tendons; teeth; cartilage

Definitions

  • JOSEPH ROSS IIUNTER OF PHILADELPHIA, PENNSYLVANIA, ASSIGNOR TO ⁇ YILLIAH HINCKLE SMITH, OI PHILADELPHIA, PENNSYL ANIA.
  • My invention consists of a new product from l bone.
  • I may omit the removal of the fatty matter pm .w' and carry out the invention in the manner hereinafter described, removing the fatty matter as a part of the same operation that is required to remove the mineral salts.
  • I preferably wash the bone thoroughly to remove the tlesh or foreign matter therefrom, cut it up to make it more convenient for the handling, and to render all parts of the hone more easily accessible to the treating fluid, and thus place it in vessels containing a solution of hydrochloric acid (HUI) and water.
  • the per centage of hydrochloricacid used is preferably relatively small, being about twenty per cent, but varies slightly, according to the character of the bon whether fresh or dead, and the temperature at which the process is to be carried out.
  • the extent of action of hydrochloric acid upon the mineral salts relatively to the action upon the fiber of the bone which I wish to retain depends upon the tempera ture, and I have found that the most suitable temperature is in the vicinity of blood-heat.
  • the fiber remaining from the hydrochloricacid treatment, ordinarily termed ossein," is then washed thoroughly and the hydrochloric acid removed by churning or otherwise working in a solution of sal-soda. If the bone fiber has at this time an objectionable color, itmay be bleached by chlorid of lime without in- E terfering with the result which I wish to obtain.
  • the bone fiber is preferably kept wet until the process is complete, but may be moistened if it dries too much.
  • the bone is put into a beating-engine and thoroughly beaten. This breaks the fiber up somewhat; but I preferably divide it, and I complete the division in a refining or Jordan l engine to the fineness required for the purpose to which it is to be applied.
  • the resultant fibers are pliable and soft and have a l ragged body caused by the projection of small l spurs, filaments, splints, or particles therefrom much as is the case with wool, and the i same result is obtained from this fiber in my product as in wool namely, that it may be felted or woven to advantage, and under strong pressure it may be formed into masses or sheets without the use of adhesive.
  • the coarse products are used for the bulky articles and for those requiring comparatively little capability or necessity of flexure and are preferably united without an adhesive; but for the liner and more delicate fabrics and products a sizing is preferably used.
  • My material is a non-conductor of heat and of electricity: and even in the divided form will not take fire nor readily support combustion. In the compressed form it is substantially fireproof, and it is at all times impervious to moisture.
  • shrec 20 ded cartilaginous residuum from bone.

Description

l fe. 781,880.
UWTED STATES Patented February '7, 1905.
PATENT QFFTCE,
JOSEPH ROSS IIUNTER, OF PHILADELPHIA, PENNSYLVANIA, ASSIGNOR TO \YILLIAH HINCKLE SMITH, OI PHILADELPHIA, PENNSYL ANIA.
PRODUCT FROM BONE.
SPECIFICATION forming part of Letters Patent No. 781,880, dated February '7, 1905.
' Application tiled June 29, 1904. Serial No, 214,618.
Be it known that I, J osnrn Ross HUNTER, a citizen of the United States, residing in the city and county of Philadelphia, State of Pennsylvania, have invented a novel Construction of Products from Bone, of which the following is a specification.
My invention consists of a new product from l bone.
In carrying out my invention I treat bone of any kind in any suitable manner to remove from it fatty matter and then remove the mineral salts, particularly lime, therefrom,
or I may omit the removal of the fatty matter pm .w' and carry out the invention in the manner hereinafter described, removing the fatty matter as a part of the same operation that is required to remove the mineral salts. I preferably wash the bone thoroughly to remove the tlesh or foreign matter therefrom, cut it up to make it more convenient for the handling, and to render all parts of the hone more easily accessible to the treating fluid, and thus place it in vessels containing a solution of hydrochloric acid (HUI) and water. The per centage of hydrochloricacid used is preferably relatively small, being about twenty per cent, but varies slightly, according to the character of the bon whether fresh or dead, and the temperature at which the process is to be carried out. The extent of action of hydrochloric acid upon the mineral salts relatively to the action upon the fiber of the bone which I wish to retain depends upon the tempera ture, and I have found that the most suitable temperature is in the vicinity of blood-heat. The fiber remaining from the hydrochloricacid treatment, ordinarily termed ossein," is then washed thoroughly and the hydrochloric acid removed by churning or otherwise working in a solution of sal-soda. If the bone fiber has at this time an objectionable color, itmay be bleached by chlorid of lime without in- E terfering with the result which I wish to obtain. The bone fiber is preferably kept wet until the process is complete, but may be moistened if it dries too much. From the soda-washing or from the bleaching process the bone is put into a beating-engine and thoroughly beaten. This breaks the fiber up somewhat; but I preferably divide it, and I complete the division in a refining or Jordan l engine to the fineness required for the purpose to which it is to be applied. The resultant fibers are pliable and soft and have a l ragged body caused by the projection of small l spurs, filaments, splints, or particles therefrom much as is the case with wool, and the i same result is obtained from this fiber in my product as in wool namely, that it may be felted or woven to advantage, and under strong pressure it may be formed into masses or sheets without the use of adhesive. The coarse products are used for the bulky articles and for those requiring comparatively little capability or necessity of flexure and are preferably united without an adhesive; but for the liner and more delicate fabrics and products a sizing is preferably used.
My material is a non-conductor of heat and of electricity: and even in the divided form will not take fire nor readily support combustion. In the compressed form it is substantially fireproof, and it is at all times impervious to moisture.
Where reference is made herein to the removal of fluid fatty matter and lime or mineral matter, and particularly the last two named, or to material as free from these substances, the substantial removal of and substantial freedom from these substances will be understood to be intended, as an absolute removal of them, and particularly of the mineral matter is most ditlicult without the destruction of the fibrous residuum, and for most, if not all, purposes the entire removal of these substances is unnecessary. \Vhere ref- .erence is made herein to lime or delimed bone, it will be understood that the lime or deliming refers to such mineral matter as contains calcium, which, as is well known, exists in bone largely in the form of a phosphate.
It will be evident that various changes may l be made by those skilled in the art which may 4:. As a new product of manufacture, ossein fibers having spurs or filaments projecting 5 therefrom.
5. Asa new product of manufacture fibers from bone separated along general lines of natural cleavage.
6. As anew product of manufacture, shrec 20 ded cartilaginous residuum from bone.
JOSEPH ROSS HUNTER.
Vitnesses:
JOHN A. VVIEDERSHEIM, VVM. S. JAoKsoN.
US21461804A 1904-06-29 1904-06-29 Product from bone. Expired - Lifetime US781880A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US21461804A US781880A (en) 1904-06-29 1904-06-29 Product from bone.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21461804A US781880A (en) 1904-06-29 1904-06-29 Product from bone.

Publications (1)

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US781880A true US781880A (en) 1905-02-07

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US21461804A Expired - Lifetime US781880A (en) 1904-06-29 1904-06-29 Product from bone.

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539549A (en) * 1969-02-27 1970-11-10 Charles Greenfield Recovery of protein from bone

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539549A (en) * 1969-02-27 1970-11-10 Charles Greenfield Recovery of protein from bone

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