US5853752A - Methods of preparing gas and gaseous precursor-filled microspheres - Google Patents

Methods of preparing gas and gaseous precursor-filled microspheres Download PDF

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Publication number
US5853752A
US5853752A US08/487,230 US48723095A US5853752A US 5853752 A US5853752 A US 5853752A US 48723095 A US48723095 A US 48723095A US 5853752 A US5853752 A US 5853752A
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US
United States
Prior art keywords
gaseous precursor
method
lipid
liposomes
methane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US08/487,230
Inventor
Evan C. Unger
Thomas A. Fritz
Terry Matsunaga
VaradaRajan Ramaswami
David Yellowhair
Guanli Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ImaRx Therapeutics Inc
Bristol Myers Squibb Pharma Co
Lantheus Medical Imaging Inc
Original Assignee
ImaRx Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US45570789A priority Critical
Priority to US07/569,828 priority patent/US5088499A/en
Priority to US71689991A priority
Priority to US07/717,084 priority patent/US5228446A/en
Priority to US08/076,239 priority patent/US5469854A/en
Priority to US15967493A priority
Priority to US08/159,687 priority patent/US5585112A/en
Priority to US08/160,232 priority patent/US5542935A/en
Priority to US08/487,230 priority patent/US5853752A/en
Application filed by ImaRx Pharmaceutical Corp filed Critical ImaRx Pharmaceutical Corp
Assigned to IMARX PHARMACEUTICAL CORPORATION reassignment IMARX PHARMACEUTICAL CORPORATION ROSS REFERENCE OF ASSIGNMENT ORIGINALLY RECORDED IN PARENT CASE (SERIAL NO. 08/159,787) ON JULY 28, 1995 AT REEL 7569, FRAMES 0038-0042. Assignors: FRITZ, THOMAS A., MATSUNAGA, TERRY, RAMASWAMI, VARADARAJAN, UNGER, EVAN C., WU, GUANLI, YELLOWHAIR, DAVID
Publication of US5853752A publication Critical patent/US5853752A/en
Application granted granted Critical
Assigned to DUPONT PHARMACEUTICALS COMPANY reassignment DUPONT PHARMACEUTICALS COMPANY CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: IMARX PHARMACEUTICAL CORP
Assigned to SILICON VALLEY BANK reassignment SILICON VALLEY BANK SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: IRMARX THERAPEUTICS, INC.
Assigned to BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. reassignment BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: DUPONT CONTRAST IMAGING INC.
Assigned to BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. reassignment BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: DUPONT CONTRAST IMAGING INC.
Assigned to DUPONT CONTRAST IMAGING INC. reassignment DUPONT CONTRAST IMAGING INC. MERGER/CHANGE OF NAME Assignors: IMARX PHARMACEUTICAL CORP.
Priority claimed from US10/113,577 external-priority patent/US20020150539A1/en
Priority claimed from US10/213,600 external-priority patent/US20030003055A1/en
Assigned to IMARX THERAPEUTICS, INC. reassignment IMARX THERAPEUTICS, INC. RELEASE Assignors: SILICON VALLEY BANK
Assigned to IMARX THERAPEUTICS, INC. reassignment IMARX THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: IMARX PHARMACEUTICAL CORPORATION
Assigned to ABLECO FINANCE LLC, AS COLLATERAL AGENT reassignment ABLECO FINANCE LLC, AS COLLATERAL AGENT GRANT OF SECURITY INTEREST Assignors: BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC.
Assigned to LANTHEUS MEDICAL IMAGING, INC. reassignment LANTHEUS MEDICAL IMAGING, INC. CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC.
Assigned to LANTHEUS MEDICAL IMAGING, INC. reassignment LANTHEUS MEDICAL IMAGING, INC. RELEASE OF PATENT SECURITY AGREEMENT Assignors: ABLECO FINANCE LLC
Assigned to HARRIS N.A., AS COLLATERAL AGENT reassignment HARRIS N.A., AS COLLATERAL AGENT SECURITY AGREEMENT Assignors: LANTHEUS MEDICAL IMAGING, INC.
Assigned to WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ASSIGNEE reassignment WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ASSIGNEE ASSIGNMENT OF SECURITY INTEREST IN PATENTS Assignors: BMO HARRIS BANK N.A.
Anticipated expiration legal-status Critical
Assigned to LANTHEUS MEDICAL IMAGING, INC., LANTHEUS HOLDINGS, INC., LANTHEUS MI REAL ESTATE, LLC reassignment LANTHEUS MEDICAL IMAGING, INC. RELEASE OF SECURITY INTEREST IN CERTAIN PATENTS Assignors: WELLS FARGO BANK, NATIONAL ASSOCIATION
Application status is Expired - Lifetime legal-status Critical

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