US553907A - Suppository and method of making same - Google Patents
Suppository and method of making same Download PDFInfo
- Publication number
- US553907A US553907A US553907DA US553907A US 553907 A US553907 A US 553907A US 553907D A US553907D A US 553907DA US 553907 A US553907 A US 553907A
- Authority
- US
- United States
- Prior art keywords
- suppository
- sections
- integument
- tin
- foil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000829 suppository Substances 0.000 title description 39
- 238000004519 manufacturing process Methods 0.000 title description 3
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 13
- 239000000463 material Substances 0.000 description 9
- 239000003814 drug Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000002198 insoluble material Substances 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/08—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
Definitions
- This invention relates to suppositories and analogous articles, composed in whole or in part of medicinal ingredients, which, when molded or shaped into a definite form, are very difficult to handle or transport, and are exceedingly liable to lose their original form or shape, and be seriously damaged if unprotected or exposed at any or all points to the action of the atmosphere.
- the chief object of my present invention is to provide a suppository or analogous article with a new and improved external covering or protecting medium which possesses such characteristic features that it effectirally and perfectly excludes the atmosphere, retains the inclosed article in its original molded form, and is susceptible of being conveniently and swiftly removed entirely from the suppository or analogous article whenever the latter is to be applied to the purpose for which it is designed. This object is accomplished in the manner and by the means hereinafter described and claimed.
- Figure 1 is a perspective view of a suppository inclosed within a pro tecting-integument according to my invention.
- Fig. 2 is a transverse sectional view of the same.
- Fig. 3 is a detail perspective view showing the two similar sections prior to their application to the suppository.
- Fig. 3 is a detail view of a cap or end piece for covering the exposed end of the suppository.
- Fig. a is a detailperspective view of separable moldsections in which the suppositories are molded into the desiredform and inclosed in the intcguments, a pair of the integument-sections being shown in position in the parts of one mold-cavity.
- FIG. 5 is a detail perspective view of the two parts or sections of a forming device for imparting a form or shape to the integumentsections corresponding to the form or shape of the molded suppository.
- Fig. 6 is a detail perspective view of the diesections for uniting the rims of the integument-sections and compressing the folded edges of such rims.
- Fig. 7 is a sectional view of the die-sections, showing how the rims of the integument-sections are united and their edges turned. laterally.
- Fig. 8 is a similar view showing how the folded edges of the rims are compressed to make air-tight joints, and
- Fig. 9 is a detail longitudinal sectional view showing how one end of the inclosing integument can be made of suificient length to be folded over and thus close such end.
- the sections 1 and 2 are preferably composed of tin-foil, but they may be made of starch-paper or any other material'suitable for the purpose in hand, and which has no. special affinity for or will not too closely adhere to the suppository or analogous article when the latter is inclosed between the sections composing the integument.
- the tin-foil or other protecting-sections are formed with continuous laterally-projecting rims 3 and 4, which may be of any suitable width, but in actual practice are one-fourth of an inch in width, more or less. tions are each formed or shaped into approxi- The secmately the form or shape oi the suppository or analogous article to be covered and pro- Thisisreadilyaccomplishedthrough tected. the medium of a former, which is illustrated in Fig. 5.
- This former comprises sections and U.
- the section is constructed with a cavity 7, corresponding exactly, or approximately, with the form or shape of the suppository which is to be covered or protected.
- the section i is constructed with a projecting former 8, of a shape which will accurately lit into the cavity 7.
- the sections composing the integument are formed by placing suitable pieces of tin-toil or starch-paper over the cavity in the former-section U, and then placing the two former-sections together and causing the former S of the section 6 to press the tin foil or starch paper down into the cavity 7 in such manner as to leave the edge of each piece of tin-i'oil or starch-paper extending laterally to term the continuous rims corresponding to the rims 3 and l, hereinbe- :t'ore mentioned.
- the molded or shaped sections of tin-foil or starch-paper are then placed in the moldcavities 9 of the separable mold sectious i l, and after the latter are tightly clamped together the hot fluid, or seniil'luid material from which the suppositories are to be produced, is introduced intothe mold-cavities bei that it provides for the swift removal of the tween the sections of tin-toil or starch-paper.
- the apparatus for heating the material and introducing the same into the molds is preferably such as is described and shown in my ument-sections 1 and 2 may be covered and application for Letters Patent filed of even date herewith, Serial No. 550,445.
- the suppositories are properly shaped by the separable mold-sections, the latter are opened and the suppositories covered with the tin-foil or starch-palier are carefully removed and laid one at a time into the cavity 12 of a lower die-section 13, which cavity is of a form corresponding to the form of the suppository.
- the wall of the cavity 12 is formed with a horizontal top edge 11 to receive and support the laterally-projecting rim, which extends continuously in a longitudinal direction entirely around the suppository.
- the other dieblock section 15 is then pressed upon the die-section 13, which section 15 contains a cavity 16, similar in shape to the cavity 12, and is constructed with a continuous shoulder 17 and rim 1R, both having a shape corresponding approximately to the shape of the incased suppository.
- the shoulder 17 co-opcrates with the flat top edge ll of the die-section 13 to compress the laterally-projecting rims of the tin-foil or starch-paper sections tightly together, so that they are securely united.
- the rim 18 presses the outer edge of the united tin-foil or starch-paper rims upon the outer surfaces of the die-block sections 13 around the horizontal or flat edge l-l, after which the die-sections are separated, the suppository is reversed in position in the die-section 1 3, the edge of the rim is folded over, and
- the diesection i5 is again operated, so that the folded outer edge 3 of the tin-toil or paper-rim is tightly compressed for the purpose of hermetit'iallyscaling the joint or seam, and rendering it impossible for the atmosphere to gain access to the incloscd suppository.
- the folding of the edge of the rim of the inelosing integument is a very desirable and important feature, in that it provides a hermetically'sealed joint which effectually ex.- cludes the atmosphere.
- the laterally-projecting rim constitutes in one sense a lingerpiece which affords ample means for conveniently and swiftly tearing off the tin-foil covering or protecting-integument whenever the suppository or analogous article is to be applied to the purpose for which it is designed.
- the tin-foil or equivalent material will not unduly adhere or stick to the material of which the suppository or analogous article is composed. and the rim provides such a project ing part that the entire covering can be very quickly and entirely removed without liability of damaging the suppository in any manner.
- the rim is a very advantageous element, in
- integumcnt which is very important when it; is considered that the suppository itsellf is very susceptible to heat, and if retained in the fingers an undue length of time in removing the covering the suppository is likely to melt or lose its original. molded form or shape.
- This cap-piece can be molded or shaped into the desired form, and the semicylindrical portions 20 will fit over the end portion of the covered suppository, while the lateral lips 21 can be folded around the rim of the protecting-integument.
- Fig. 9 the two sections 1 and 2, composin g the inclosing integument, are of such length that when applied ashereinbefore eX-- plained the integument extends to such extent that it can be folded over upon itself, as clearly indicated by dotted lines, for the purpose of closing one end of the integument airtight.
- a protecting covering or integument possessing the characteristics described is easily removable, it prevents the article deteriorating in efficacy or becoming contaminated, it preserves the form or shape of the article, and in the molding operation the integument-sections prevent any and all parts of the suppository from adhering 0r sticking to the surfaces of the metal or other mold.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Description
' (No Model.)
- D. GENESE. SUPPOSITORY AND METHOD OF MAKING SAME.
N0.55s,907. Patented Peb.4, 1896. I
UNTTED STATES PATENT OFFICE.
DAVID GENESE, OF BALTIMORE, MARYLAND, ASSIGNOR, BY DIRECT AND MESNE ASSIGNMENTS, TO THE GENESE COMPRESSOR AND MOULDING MACHINE COMPANY OF BALTIMORE CITY, OF MARYLAND.
SUPPOSITORY AND METHOD OF MAKING SAME.
SPECIFICATION forming part of Letters Patent No. 553,907, dated February 4, 1896.
Application filed May 23, 1895. Serial No. 550,444. (No specimens.)
T0 to whom it may concern:
Be it known that 1, DAVID GENEsn, a citizen of the United States, residing at Baltimore city, in the State of Maryland, have invented new and useful Improvements in Pro tecting-Integiunents for Suppositories, 850., of which the following is a specification.
This invention relates to suppositories and analogous articles, composed in whole or in part of medicinal ingredients, which, when molded or shaped into a definite form, are very difficult to handle or transport, and are exceedingly liable to lose their original form or shape, and be seriously damaged if unprotected or exposed at any or all points to the action of the atmosphere.
The chief object of my present invention is to provide a suppository or analogous article with a new and improved external covering or protecting medium which possesses such characteristic features that it effectirally and perfectly excludes the atmosphere, retains the inclosed article in its original molded form, and is susceptible of being conveniently and swiftly removed entirely from the suppository or analogous article whenever the latter is to be applied to the purpose for which it is designed. This object is accomplished in the manner and by the means hereinafter described and claimed.
In order to enable my invention to be clearly understood, I have in the accompanying drawings illustrated, in addition to the suppository itself, a series of molds for shaping the suppositories, a former for imparting to the sections of the integument a definite shape corresponding to the form of the article which is to be inclosed thereby, and a die for uniting the rims of the integument-sections together and compressing the folded edges of such rims.
In the accompanying drawings, illustrating my invention, Figure 1 is a perspective view of a suppository inclosed within a pro tecting-integument according to my invention. Fig. 2 is a transverse sectional view of the same. Fig. 3 is a detail perspective view showing the two similar sections prior to their application to the suppository. Fig. 3 is a detail view of a cap or end piece for covering the exposed end of the suppository. Fig. a is a detailperspective view of separable moldsections in which the suppositories are molded into the desiredform and inclosed in the intcguments, a pair of the integument-sections being shown in position in the parts of one mold-cavity. Fig. 5 is a detail perspective view of the two parts or sections of a forming device for imparting a form or shape to the integumentsections corresponding to the form or shape of the molded suppository. Fig. 6 is a detail perspective view of the diesections for uniting the rims of the integument-sections and compressing the folded edges of such rims. Fig. 7 is a sectional view of the die-sections, showing how the rims of the integument-sections are united and their edges turned. laterally. Fig. 8 is a similar view showing how the folded edges of the rims are compressed to make air-tight joints, and Fig. 9 is a detail longitudinal sectional view showing how one end of the inclosing integument can be made of suificient length to be folded over and thus close such end.
In order to enable those skilled in the art to practice my invention, I will now describe the same in detail, referring to the drawings, wherein The numerals 1 and 2 indicate two similar sections having an outline substantially the same as the outline of the suppository or analogous article which is to be covered and protected.
The sections 1 and 2 are preferably composed of tin-foil, but they may be made of starch-paper or any other material'suitable for the purpose in hand, and which has no. special affinity for or will not too closely adhere to the suppository or analogous article when the latter is inclosed between the sections composing the integument.
The tin-foil or other protecting-sections are formed with continuous laterally-projecting rims 3 and 4, which may be of any suitable width, but in actual practice are one-fourth of an inch in width, more or less. tions are each formed or shaped into approxi- The secmately the form or shape oi the suppository or analogous article to be covered and pro- Thisisreadilyaccomplishedthrough tected. the medium of a former, which is illustrated in Fig. 5. This former comprises sections and U. The section is constructed with a cavity 7, corresponding exactly, or approximately, with the form or shape of the suppository which is to be covered or protected. The section i is constructed with a projecting former 8, of a shape which will accurately lit into the cavity 7. The sections composing the integument are formed by placing suitable pieces of tin-toil or starch-paper over the cavity in the former-section U, and then placing the two former-sections together and causing the former S of the section 6 to press the tin foil or starch paper down into the cavity 7 in such manner as to leave the edge of each piece of tin-i'oil or starch-paper extending laterally to term the continuous rims corresponding to the rims 3 and l, hereinbe- :t'ore mentioned.
The molded or shaped sections of tin-foil or starch-paper are then placed in the moldcavities 9 of the separable mold sectious i l, and after the latter are tightly clamped together the hot fluid, or seniil'luid material from which the suppositories are to be produced, is introduced intothe mold-cavities bei that it provides for the swift removal of the tween the sections of tin-toil or starch-paper.
The introduction of the material in a hot condition into the tin-foil integumcnt secures an air-tight adjustment of the suppository material, and is very important for the preservation of the suppository.
The apparatus for heating the material and introducing the same into the molds is preferably such as is described and shown in my ument-sections 1 and 2 may be covered and application for Letters Patent filed of even date herewith, Serial No. 550,445.
\Vhen the suppositories are properly shaped by the separable mold-sections, the latter are opened and the suppositories covered with the tin-foil or starch-palier are carefully removed and laid one at a time into the cavity 12 of a lower die-section 13, which cavity is of a form corresponding to the form of the suppository.
The wall of the cavity 12 is formed with a horizontal top edge 11 to receive and support the laterally-projecting rim, which extends continuously in a longitudinal direction entirely around the suppository. The other dieblock section 15 is then pressed upon the die-section 13, which section 15 contains a cavity 16, similar in shape to the cavity 12, and is constructed with a continuous shoulder 17 and rim 1R, both having a shape corresponding approximately to the shape of the incased suppository. The shoulder 17 co-opcrates with the flat top edge ll of the die-section 13 to compress the laterally-projecting rims of the tin-foil or starch-paper sections tightly together, so that they are securely united. The rim 18 presses the outer edge of the united tin-foil or starch-paper rims upon the outer surfaces of the die-block sections 13 around the horizontal or flat edge l-l, after which the die-sections are separated, the suppository is reversed in position in the die-section 1 3, the edge of the rim is folded over, and
the diesection i5 is again operated, so that the folded outer edge 3 of the tin-toil or paper-rim is tightly compressed for the purpose of hermetit'iallyscaling the joint or seam, and rendering it impossible for the atmosphere to gain access to the incloscd suppository.
The folding of the edge of the rim of the inelosing integument is a very desirable and important feature, in that it provides a hermetically'sealed joint which effectually ex.- cludes the atmosphere. The laterally-projecting rim constitutes in one sense a lingerpiece which affords ample means for conveniently and swiftly tearing off the tin-foil covering or protecting-integument whenever the suppository or analogous article is to be applied to the purpose for which it is designed. The tin-foil or equivalent material will not unduly adhere or stick to the material of which the suppository or analogous article is composed. and the rim provides such a project ing part that the entire covering can be very quickly and entirely removed without liability of damaging the suppository in any manner.
The rim is a very advantageous element, in
integumcnt, which is very important when it; is considered that the suppository itsellf is very susceptible to heat, and if retained in the fingers an undue length of time in removing the covering the suppository is likely to melt or lose its original. molded form or shape.
The exposed extremity of the suppository of analogous article lying between the integproteeted by stearine-papor, para-dine, or any other material, or it may be covered with a tin-foil or starch-paper cap-piece 19, which is clearly shown in Fig. This cap-piece can be molded or shaped into the desired form, and the semicylindrical portions 20 will fit over the end portion of the covered suppository, while the lateral lips 21 can be folded around the rim of the protecting-integument.
In Fig. 9 the two sections 1 and 2, composin g the inclosing integument, are of such length that when applied ashereinbefore eX-- plained the integument extends to such extent that it can be folded over upon itself, as clearly indicated by dotted lines, for the purpose of closing one end of the integument airtight.
It will be observed from the foregoing that it is proposed to close one end of the integument either by covering the exposed end of the suppository with starch-paper or paraftine or by applying thereto a tin-foil or other cap-piece 10, Fig. 3", or by making the integument-sections of such length that one end of the integument can be folded over upon it self, as in Fig. 9.
I do not wish to be understood as confining myself to any particular means for closing the end of the integument into which the material composing the suppository is introduced.
A protecting covering or integument possessing the characteristics described is easily removable, it prevents the article deteriorating in efficacy or becoming contaminated, it preserves the form or shape of the article, and in the molding operation the integument-sections prevent any and all parts of the suppository from adhering 0r sticking to the surfaces of the metal or other mold.
Having thus described my invention, what I claim is- 1. The method herein described of making suppositories, which consists in reducing a medicament to a fluid condition by heat, lining a mold with sections of insoluble material, such as tin-foil, introducing the hot medicament into the mold between the sec-= tions of the insoluble material, subsequently DAVID GENESE/ \Vitnesses:
GEo. M. CAFFRAY, CHAS. H. SHIPLEY.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US553907A true US553907A (en) | 1896-02-04 |
Family
ID=2622646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US553907D Expired - Lifetime US553907A (en) | Suppository and method of making same |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US553907A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2613397A (en) * | 1946-05-29 | 1952-10-14 | Owens Corning Fiberglass Corp | Manufacture of molded articles |
| US2888783A (en) * | 1953-02-12 | 1959-06-02 | Frederick W Turnbull | Mold for applying enamel |
-
0
- US US553907D patent/US553907A/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2613397A (en) * | 1946-05-29 | 1952-10-14 | Owens Corning Fiberglass Corp | Manufacture of molded articles |
| US2888783A (en) * | 1953-02-12 | 1959-06-02 | Frederick W Turnbull | Mold for applying enamel |
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