US5409466A - Transdermal injection appliance - Google Patents

Transdermal injection appliance Download PDF

Info

Publication number
US5409466A
US5409466A US08186280 US18628094A US5409466A US 5409466 A US5409466 A US 5409466A US 08186280 US08186280 US 08186280 US 18628094 A US18628094 A US 18628094A US 5409466 A US5409466 A US 5409466A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
needle
sleeve
injection
fig
end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
US08186280
Inventor
Robert L. Watson
Robert C. Shober, Jr.
Original Assignee
Watson; Robert L.
Shober, Jr.; Robert C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287Accessories for bringing the needle into the body; Automatic needle insertion

Abstract

A transdermal injection appliance has a pad impregnated with a disinfectant solution such as alcohol, a body with adhesive for holding the pad against the skin of a patient, and a sleeve with a guide passage through the body for guiding an injection needle. A membrane puncturable by the needle is attached to the sleeve to close the passage, the membrane being self-sealing so that an opening through the membrane formed by the needle is closed as soon as the needle is extracted, thereby wiping a majority of blood from the needle and preventing the escape of blood. The tubular sleeve can have an outer end with a coupling for connection to a retractable needle injection assembly. A method of using the appliance with the retractable needle assembly to administer medication without exposing the health care giver to accidental contact with the needle is also disclosed.

Description

CROSS-REFERENCE TO RELATED APPLICATION

This is a division of application Ser. No. 08/109,935 filed Aug. 17, 1993, now U.S. Pat. No. 5,342,319.

FIELD OF THE INVENTION

This invention relates to an appliance for facilitating the safe use of an injection needle by protecting the health care provider from accidental contact with the needle and also protecting the provider from contact with the blood of a patient.

CROSS-REFERENCE TO RELATED APPLICATION

The device of this invention is advantageously used in conjunction with a retractable injection needle assembly disclosed and claimed in U.S. patent application Ser. No. 936,338, Shober et al, filed Aug. 28, 1992, now U.S. Pat. No. 5,279,583, which is hereby incorporated by reference.

BACKGROUND OF THE INVENTION

U.S. patent application Ser. No. 936,338 discloses a needle assembly which has the advantages of housing a needle so that the user is protected from accidental puncture. In that apparatus, a syringe is coupled to a housing which contains the needle and covers it unless intentional steps are taken to cause the point to be exposed during connection to a medication container, a medication delivery apparatus or during intravenous or transcutaneous injection.

However, that application does not treat the problems associated with contact of the health care provider with the blood or serum of the patient during or after an injection. Since contact with the blood or serum of a person infected with certain contagious viruses can be highly dangerous, it is important to avoid such contact.

Normally, before an injection, the area of the skin to be punctured is cleaned with a substance such as alcohol. Following the injection, the needle puncture bleeds to some extent and is typically covered with sterile cotton, sometimes held in place with someone's finger or a small adhesive bandage. A danger exists that accidental contact with the blood emanating from the puncture can occur at that stage of the process.

SUMMARY OF THE INVENTION

Accordingly, an object of the present invention is to provide an appliance that permits transdermal administration of medication by injection with a hypodermic needle and eliminates exposure of the health care provider to blood or an exposed needle and which is also useful as a penetration site for an intravenous (IV) catheter.

A further object is to provide such an appliance which includes means for decontaminating the skin and a .self-sealing membrane through which an injection needle can be inserted and withdrawn.

Another object is to provide an appliance which is suited for attachment to the skin of a patient to facilitate injection and which can be left on the patient following injection until after the injection puncture has stopped bleeding.

A still further object is to provide such an appliance which is provided with a coupling for connection of a retractable needle injection assembly.

Briefly described, the invention comprises a disk having adhesive means for holding the disk on the skin of a patient. The disk has a pad with alcohol or a similar disinfectant therein. A central guide passage through the disk allows the passage of an injection needle, the passage being closed by a membrane which can be punctured by the needle and which is self-sealing so that an opening through the membrane formed by the needle is closed as soon as the needle is extracted, thereby preventing the escape of blood.

The disk itself may alternatively or additionally be impregnated with the disinfectant, allowing the separate pad to be omitted. The membrane can also be a laminated body. When the needle is withdrawn, the needle is wiped relatively clean by a layer of the membrane, reducing exposure to blood.

Additionally, the disk preferably has a coupling for connection to a retractable needle injection assembly.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to impart full understanding of the manner in which these and other objects are attained in accordance with the invention, particularly advantageous embodiments thereof will be described with reference to the accompanying drawings, which form a part of this disclosure, and wherein:

FIG. 1 is an enlarged side elevation, in partial section, of a first embodiment of an appliance in accordance with the invention;

FIG. 2 is a partial top plan view of the device of FIG. 1 with a top cover removed;

FIG. 3 is a partial bottom plan view of the device of FIGS. 1 and 2 with a bottom cover removed;

FIG. 4 is a side elevation, in section, of an automatic needle retracting syringe assembly usable to extract medication from a supply vial;

FIG. 5 is a side elevation, in section of the automatic needle retracting syringe assembly of FIG. 4 coupled to an appliance in accordance with the present invention;

FIG. 6 is a side elevation in partial section of a further embodiment of the invention;

FIG. 7 is a top plan view of another embodiment of the present invention; and

FIG. 8 is a side view, in section, of yet another embodiment of the invention.

DESCRIPTION OF THE PREFERRED EMBODIMENTS

Referring to FIGS. 1-3, the appliance includes an annular, disk-shaped body 10 which is preferably made of a soft elastomer or flexible foam, of either the open- or closed-cell type. Body 10 has a coating 12 of an adhesive such as is commonly used on small adhesive bandages, the primary characteristics of the adhesive being that it is capable of adhering to human skin without harming the skin. Body 10 has a central opening 13 and a recess 14 which receives a disk-shaped, alcohol-impregnated pad 16. Pad 16 is made of a compressible material and is formed with a central recess so that it can be compressed largely into recess 14. Pad 16 can also, or alternatively, be impregnated with a topical anesthetic or disinfectant. A removable and disposable cover 18 is shaped to cover the adhesive surface 12 of body 10 as well as the exposed surface of pad 16. Cover 18 is made of a material which releases from the adhesive in the manner of the disposable covers for a conventional adhesive bandage.

A tubular plastic sleeve 20 extends into central opening 13 of the body, sleeve 20 having a central lumen 22 which is dimensioned to receive an injection needle. At the inner or lower end of sleeve 20 is a resealable laminated membrane 24 made of a self-repairing elastomeric material such as Silastic or latex. In addition to being self-sealing so that it closes after a needle has passed therethrough and been removed, membrane 24 is impervious to blood and serum and should be compatible with skin contact.

At the outer or upper end of sleeve 20 are protruding ears 26 formed and dimensioned to act as one-half of a coupling such as a standard Luer-Lok® fitting so that a retracting needle assembly in accordance with previously mentioned application Ser. No. 936,338 can be connected thereto. An annular, disk-shaped collar 28 of rather stiff or rigid plastic material can also be provided surrounding sleeve 20 for stabilizing purposes. Depending on the materials selected for the other components, collar 28 may not be necessary. However, if needed, it can conveniently be manufactured as an integral part of sleeve 20.

Finally, a peel-off dome cover 30 covers the upper surfaces of body 10, collar 28 and sleeve 20 until the device is ready for use.

In use, cover 18 is removed and discarded and the adhesive surface 12 of body 10 is pressed against the skin of a patient so that it adheres to the area surrounding the desired location for an injection. At this time, pad 16 is compressed by pressure with the skin and discharges a sufficient amount of alcohol to decontaminate the injection area. It is also possible for the health care provider to rub the area with the pad 16 before adhering body 10 to the skin. Alternatively or additionally, as mentioned above, the pad can contain an anesthetic to numb the injection area.

Cover 30 is then removed and an injection needle 32 is passed through lumen 22 of sleeve 20 and through membrane 24, puncturing the membrane. Lumen 22 guides the needle as it passes through pad 16 and into the skin of the patient to which body 10 is adhered. A syringe, not shown in FIGS. 1-3, is then actuated to discharge medication through needle 32 and into the patient in a conventional fashion.

The needle is then extracted from the patient and withdrawn through pad 16 and membrane 24. At this time, the membrane reseals itself, closing the opening so that any discharge of blood or serum from the injection puncture is prevented from entering lumen 22. The needle is disposed of in a standard manner. Body 10 is not removed from the patient's skin at this time. Rather, it remains so that the alcohol in the pad can continue to have a disinfecting effect and so that the pad can absorb the small amount of blood or serum discharge which commonly follows an injection. Because pad 16 is compressed when it is applied, it applies gentle pressure to the area of the puncture to stop bleeding. No separate cotton ball or bandage is required since the pad performs the functions thereof. After an hour or so, the entire device can be removed and discarded, the skin puncture having healed itself sufficiently to require no further attention in most cases.

As will be apparent to one skilled in the art, the appliance described thus far can be used with any conventional needle and syringe and is quite useful, but its use with a conventional, exposed needle does not solve the related problem of protecting the health care provider from possible contact with the needle before or after the injection is given. Contact with the needle after injection is, of course, at least as hazardous as contact with the blood or serum if the patient has a dangerous virus.

For this reason, provision is made for connection of sleeve 20 to the retractable needle assembly mentioned above. Before discussing that connection, reference is made to FIG. 4 which shows an automatic retracting needle assembly of application Ser. No. 936,338, mentioned above. This figure and a brief description thereof is included herein for convenience and to illustrate the use of these devices in conjunction with each other to form a medication administration system.

The apparatus will be described with reference to FIG. 4 in conjunction with a conventional syringe 40 of a type having an internally threaded collar 42 at the end thereof of a type sold under the trademark Luer-Lok®. This kind of threaded collar is designed to receive the proximal end of a plastic fitting 44 holding an injection needle 46. Needles of various sizes are normally provided with a fitting similar to fitting 44 fixedly attached to the proximal end of the needle to facilitate connection of the needle to various devices such as syringes and the like, fitting 44 being similar to the fitting formed by flanges 26 of sleeve 20. The proximal end of fitting 44 has flanges 47 protruding radially in opposite directions, the peripheries of the flanges being dimensioned to be received between the lands of threads 49 within collar 42. A central spout or nipple 48 extends axially from the syringe within the threaded collar and frictionally engages a tapered interior surface of fitting 44, producing a tight fit which, in conjunction with the threads, holds the needle fitting in place and also provides a fluid-tight seal so that fluids from within the syringe 40 can be forced through the lumen of the needle. Fitting 44 also has a conical outer surface for frictionally engaging a cover or the like. Generally, the portion of the Luer-Lok® fitting having the collar and central nipple is regarded as the male portion while that with the tapered interior surface and the flanges, like fitting 44, is regarded as the female portion.

Typically, the needle initially arrives from the manufacturer in a rigid safety sleeve, not shown, which encases the needle and frictionally engages the conical outside of fitting 44, the needle and sleeve being contained in a sterile package. When it is time to use the needle, the outer package is removed and flanges 47 are inserted into collar 42 and rotated to engage threads 49 and lock the needle fitting onto the syringe. The safety sleeve is then pulled off, exposing the needle for use. The needle is a conventional needle in the sense that it is hollow and has a slanted end terminating in a very sharp point to facilitate penetration of skin or a rubber or plastic membrane, as necessary.

An assembly 50 includes a tubular spring sleeve 52 which is substantially cylindrical, the inner diameter of the proximal end of sleeve 52 being selected to frictionally engage the outer conical surface of fitting 44. The distal end of sleeve 52 is formed with an inwardly extending flange 54. Within sleeve 52 is a compression coil spring 56.

The proximal end of a generally tubular needle-encasing sleeve 58 is received within sleeve 52 and is axially slidable therein, the proximal end of sleeve 58 having an outwardly extending flange 60 which engages flange 54 to prevent sleeve 58 from completely emerging from sleeve 52. As will be recognized, one end of spring 56 engages fitting 44 and the other end thereof abuts flange 60, the length of the spring being selected so that it urges flanges 54 and 60 into abutment with each other. Thus, sleeve 58 is telescopically movable between a first position shown in FIG. 4 in which flanges 54 and 60 are in abutment and a second position in which those flanges are spaced apart and spring 56 is compressed. In the second position, sleeve 58 is almost entirely contained within sleeve 52.

Attached to the distal end of sleeve 58 is an end coupling or bell indicated generally at 62 having a first, internally threaded portion 64 and a larger un-threaded skirt portion 65. Bell 62 is provided with a recess to receive the distal end of sleeve 58 and also a rubber diaphragm 59 which extends transversely across the end of sleeve 58 and is penetrated by needle 46 to form a seal preventing the flow of fluid from the bell into the interior of sleeve 58. The distal end of sleeve 58 is fixedly attached to bell 62 by an adhesive or by heat fusion of the members together. Portion 64 is formed substantially like fitting 42 in the sense that it has the same internal diameter and similarly formed internal threads 63 for the purpose of connection to a fitting like fitting 44, if desired, which may be attached to a needle or to some other fluid-conducting device. In addition, a spout 67 extends axially into the interior of threaded portion 64 to engage the interior of a needle fitting in the same manner as spout 48 engages the inner surface of fitting 44.

Enlargement 65 may be formed at the end of the bell and dimensioned to fit over the top of a conventional medication vial indicated generally at 70. A vial of this type generally has a metal top 71 which holds a resealable rubber diaphragm 72 across the end of the vial. To remove medication for delivery to a patient, a needle is pushed through the diaphragm and a syringe attached to the needle is pulled to extract the medication from the vial. To avoid the possibility of injury to the person performing this task, enlargement 65 is positioned on the bottle top, properly centering the needle for insertion through the diaphragm. This substantially eliminates the possibility that the needle might slip to one side and stick the user.

As soon as the needle is withdrawn from the vial, it is again housed within the protective sleeves, preventing accidental puncture of the health care provider. At this stage, the syringe is filled with medication and the apparatus is ready for injecting the medication into the patient.

Without causing the needle to protrude, coupling 62 is attached to the Luer-Lok ears 26 at the top of sleeve 20 by inserting the ears into threads 63 and rotating the syringe to lock the devices together. The assembly as shown in FIGS. 1-3 will have been applied to the patient's skin, as described above. The needle is then pushed into the patient's skin and the syringe is operated in a conventional manner to inject the medication. After injection, the needle is withdrawn from the patient and is automatically again housed within the protective sleeves. Once again, the user is protected from accidental puncture because the needle is totally protected.

At this stage, it will be recognized that the entire process of loading the syringe and injecting the medication has been accomplished without at any time exposing the user to the danger of accidental puncture and without exposing the user to accidental contact with the patient's blood or serum.

A further embodiment of a transdermal injection disk in accordance with the invention is shown in FIG. 6. In this embodiment, the body 10, pad 16 and adhesive coating are substantially the same as in the embodiment of FIGS. 1-3, including the cover 18 of FIG. 1 which has been omitted from FIG. 6. The central sleeve, however, is formed as a unitarily formed sleeve and disk unit 75 wherein the sleeve portion is shorter than in the embodiment of FIG. 1 and the outer end of the sleeve portion is substantially flush with the outer surface of the disk portion. Sleeve 75 has a central lumen 76 dimensioned to receive and guide an injection needle. A resealable membrane 77 is attached to the outer end of sleeve 75 and is therefore punctured by the injection needle before the needle enters lumen 76. An outer cover 79 covers the membrane and the outer surfaces of disk 28 and body 10 and is removed before use. Membrane 77 can also be applied to the outer end of the sleeve in the embodiment of FIGS. 1-3 so long as it is attached in such a way that it does not interfere with attachment to the retractable injection needle assembly.

FIG. 7 is a top plan view of a still further embodiment of an appliance in accordance with the invention wherein a body indicated generally at 80 has a central circular portion 81 which is similar in size to a central reinforcing disk 84. Attachment tabs 82 and 83 extend radially outwardly from body portion 81, all portions thereof being coated with adhesive for attachment to the skin. A pad is received in a recess on the bottom side of the central body portion essentially as shown in FIG. 1. A sleeve 85 with coupling flanges 86 is attached as in the embodiment of FIGS. 1-3 or a sleeve is attached as shown in FIG. 6. Functionally, the embodiment of FIG. 7 is similar to those described heretofore. The advantage of the FIG. 7 embodiment is that it is smaller in overall size and may be usable in areas where use of the overall circular body may be inconvenient, although it has less absorbing area.

FIG. 8 shows an embodiment which is intended primarily to facilitate IV injections. In this embodiment, a body 10 is formed with a tubular guide 92 the central axis of which lies at an acute angle relative to the plane containing the major surfaces of the body. Preferably, the angle is between about 15° and 30°. As in the other embodiments, passage 92 is dimensioned to receive a needle 32 which is guided into a blood vessel for injecting medication, saline solution or other substances. An arrangement to perform this function also can be constructed in a manner similar to FIG. 1 or FIG. 6 but with a bellows arrangement interconnecting sleeve 20 (or the equivalent guide sleeve in FIG. 6) to body 10 so that the angle of the guide tube is adjustable. While this is more flexible in its applications, it is also more complex and expensive in construction.

FIG. 8 also illustrates the use of a laminated membrane having a layer 94 of an elastomeric material and a layer 95 of a material such as foam or the like impregnated with a disinfectant. The other characteristics of this embodiment are similar to the other embodiments described and will not be repeated.

While certain advantageous embodiments have been chosen to illustrate the invention, it will be understood by those skilled in the art that various changes and modifications can be made therein without departing from the scope of the invention as defined in the appended claims.

Claims (1)

What is claimed is:
1. A method of administering medication to a patient using an injection needle without exposing the needle comprising the steps of
providing a retractable needle assembly including an injection needle, a housing having a first portion attached to the needle, a second portion movable relative to the first portion between an extended position in which the needle is enclosed and a retracted position in which part of said needle is exposed,
coupling the assembly to a medication container,
moving the second portion to the retracted position and extracting medication from the container,
moving the second portion to the extended position enclosing the needle,
detaching the needle assembly from the container,
adhering directly to the skin of the patient an appliance having coupling means thereon matable with said second portion,
coupling the needle assembly to the appliance,
moving the second portion to the retracted position, and administering the medication to the patient by extending the needle so that the needle passes through the appliance and the patient's skin, and
removing the needle assembly from said appliance, leaving the appliance adhered to the patient's skin.
US08186280 1993-08-17 1994-01-25 Transdermal injection appliance Expired - Fee Related US5409466A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US08109935 US5342319A (en) 1993-08-17 1993-08-17 Transdermal injection appliance
US08186280 US5409466A (en) 1993-08-17 1994-01-25 Transdermal injection appliance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08186280 US5409466A (en) 1993-08-17 1994-01-25 Transdermal injection appliance
US08259854 US5496264A (en) 1993-08-17 1994-06-15 Hemostatic transdermal injection appliance

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US08109935 Division US5342319A (en) 1993-08-17 1993-08-17 Transdermal injection appliance

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US08259854 Continuation-In-Part US5496264A (en) 1993-08-17 1994-06-15 Hemostatic transdermal injection appliance

Publications (1)

Publication Number Publication Date
US5409466A true US5409466A (en) 1995-04-25

Family

ID=22330366

Family Applications (2)

Application Number Title Priority Date Filing Date
US08109935 Expired - Fee Related US5342319A (en) 1993-08-17 1993-08-17 Transdermal injection appliance
US08186280 Expired - Fee Related US5409466A (en) 1993-08-17 1994-01-25 Transdermal injection appliance

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US08109935 Expired - Fee Related US5342319A (en) 1993-08-17 1993-08-17 Transdermal injection appliance

Country Status (6)

Country Link
US (2) US5342319A (en)
EP (1) EP0678041A4 (en)
JP (1) JPH08505080A (en)
CA (1) CA2141448C (en)
FI (1) FI951755A0 (en)
WO (1) WO1995005858A3 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5728071A (en) * 1996-09-09 1998-03-17 Watson; Robert L. Injection patch
US5853399A (en) * 1995-05-26 1998-12-29 Sasaki; Hiroshi Medical instruments and systems for puncturing an organ
US5971963A (en) * 1998-08-18 1999-10-26 Choi; Soo Bong Portable automatic syringe device and injection needle unit thereof
US20040006316A1 (en) * 2002-07-02 2004-01-08 Patton Catherine C. Infusion device and method thereof
US6796967B2 (en) 2001-10-22 2004-09-28 Nps Pharmaceuticals, Inc. Injection needle assembly
WO2005118053A2 (en) * 2004-05-26 2005-12-15 Kriesel Marshall S Fluid delivery device
US20070135774A1 (en) * 2005-11-03 2007-06-14 Patton Medical Devices, Lp Fluid delivery devices, systems and methods
US20080021375A1 (en) * 2005-08-22 2008-01-24 John Burns Fluid Delivery Devices, Systems and Methods
US7985216B2 (en) 2004-03-16 2011-07-26 Dali Medical Devices Ltd. Medicinal container engagement and automatic needle device
US8376998B2 (en) 2003-09-17 2013-02-19 Elcam Medical Agricultural Cooperative Association Ltd. Automatic injection device

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2252404A1 (en) 1996-04-22 1997-10-30 Abbott Laboratories Container closure system
US5954104A (en) 1997-02-28 1999-09-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5924584A (en) * 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
US5848992A (en) * 1997-03-07 1998-12-15 Hart; Charles C. Superfascial surgical access device
CA2308217A1 (en) * 1997-10-22 1999-05-14 Elan Corporation, Plc An improved automatic syringe
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
US6904662B2 (en) 1998-04-20 2005-06-14 Becton, Dickinson And Company Method of sealing a cartridge or other medical container with a plastic closure
US6209738B1 (en) 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
DE60201121T2 (en) 2001-12-28 2005-05-19 Cane' S.R.L. Containers for disposable needle
US20040051019A1 (en) 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
US20040138602A1 (en) * 2002-10-30 2004-07-15 Rossen Joel S Simplified one-handed preemptive medical procedure site dressing to prevent sharps injuries and exposure to bloodborne pathogens
DK200201823A (en) 2002-11-26 2004-05-27 Maersk Medical As Connector for a hose connection
FR2851921B1 (en) * 2003-03-05 2006-04-07 Mokhtar Chawki Device for direct venipuncture
US20050027255A1 (en) 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
KR101158939B1 (en) 2004-03-26 2012-06-21 우노메디컬 에이/에스 Injector device for infusion set
US20050240154A1 (en) * 2004-04-21 2005-10-27 Unomedical A/S: Infusion set with patch
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
US7867199B2 (en) 2004-12-10 2011-01-11 Unomedical A/S Inserter
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
EP1948032A1 (en) * 2005-11-15 2008-07-30 Inova Medical Ag Self-closing external vessel plug with integrated wide-lumen needle
DK1962925T3 (en) 2005-12-23 2009-08-03 Unomedical As Delivery Device
EP1988958B2 (en) 2006-02-28 2016-03-16 Unomedical A/S Inserter for infusion part
CA2653631A1 (en) 2006-06-07 2007-12-13 Unomedical A/S Inserter
KR20090028701A (en) 2006-06-09 2009-03-19 우노메디컬 에이/에스 Mounting pad
KR20090037492A (en) 2006-08-02 2009-04-15 우노메디컬 에이/에스 Cannula and delivery device
JP4994775B2 (en) 2006-10-12 2012-08-08 日本コヴィディエン株式会社 Needle tip protective part
EP1917990A1 (en) 2006-10-31 2008-05-07 Unomedical A/S Infusion set
US8597253B2 (en) 2007-04-20 2013-12-03 Bard Access Systems Huber needle with safety sheath
CA2691369A1 (en) 2007-06-20 2008-12-24 Unomedical A/S A catheter and a method and an apparatus for making such catheter
US8002752B2 (en) * 2007-06-25 2011-08-23 Medingo, Ltd. Protector apparatus
CA2691341A1 (en) 2007-07-03 2009-01-08 Unomedical A/S Inserter having bistable equilibrium states
DE602008005153D1 (en) 2007-07-10 2011-04-07 Unomedical As Inserter with two feathers
KR20100049576A (en) 2007-07-18 2010-05-12 우노메디컬 에이/에스 Insertion device with pivoting action
JP2010535058A (en) * 2007-08-01 2010-11-18 メディンゴ・リミテッド Apparatus for detecting promote and bodily analyte injection of therapeutic fluid
WO2009103759A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
WO2010072664A1 (en) 2008-12-22 2010-07-01 Unomedical A/S Medical device comprising adhesive pad
US7981080B2 (en) * 2009-01-07 2011-07-19 Halaka Folim G Skin cooling apparatus and method
CN102470211B (en) 2009-07-30 2014-05-07 犹诺医药有限公司 Inserter device with horizontal moving part
CN102548598B (en) 2009-08-07 2014-09-17 犹诺医药有限公司 Delivery device with sensor and one or more cannulas
CN102844060A (en) 2010-03-30 2012-12-26 犹诺医药有限公司 Medical devices
EP2433663A1 (en) 2010-09-27 2012-03-28 Unomedical A/S Insertion system
US20120203137A1 (en) * 2011-02-03 2012-08-09 Avishai Neuman, Md, Pllc Reduced-pain needle assembly
US8486024B2 (en) 2011-04-27 2013-07-16 Covidien Lp Safety IV catheter assemblies
WO2013048975A1 (en) 2011-09-26 2013-04-04 Covidien Lp Safety catheter
WO2013048768A1 (en) 2011-09-26 2013-04-04 Covidien Lp Safety iv catheter and needle assembly
WO2013056223A1 (en) 2011-10-14 2013-04-18 Covidien Lp Safety iv catheter assembly
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US20140324021A1 (en) * 2011-11-07 2014-10-30 Eli Lilly And Company Medicinal patch and injector system
US9549873B2 (en) 2012-02-02 2017-01-24 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container
CN104244903B (en) 2012-02-02 2016-06-29 碧迪股份有限公司 Adapter for coupling to a medical container
KR20140138668A (en) 2012-02-02 2014-12-04 벡톤 디킨슨 홀딩즈 피티이 엘티디. Adaptor for coupling with a medical container
JP1526207S (en) 2013-08-05 2015-06-15
EP3164169A4 (en) * 2014-07-01 2018-03-14 Bard Inc C R Antimicrobial/haemostatic interface pad for placement between percutaneously placed medical device and patient skin
WO2017086867A1 (en) * 2015-11-19 2017-05-26 Hemcheck Sweden Aktiebolag A protective device for and method of reducing the risk to medical personnel of accidentally puncturing themselves on a hypodermic needle
CN106730062B (en) * 2017-01-07 2017-10-31 谢文盛 Intelligent means for extracting drainage of pleural effusion

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4564054A (en) * 1983-03-03 1986-01-14 Bengt Gustavsson Fluid transfer system
US5269765A (en) * 1992-03-10 1993-12-14 Injectimed, Inc. Methods of manufacture of safety sleeves for medical injection devices

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2517544A1 (en) * 1981-12-03 1983-06-10 Alby Albert Flexible foam block anchorages for catheter tubes - to inhibit accidental dislocation
WO1988006427A1 (en) * 1987-02-24 1988-09-07 Ken Heimreid A plaster for use in blood sampling
US4915694A (en) * 1987-10-02 1990-04-10 Vitaphore Corporation Antimicrobial wound dressing and skin fixator for percutaneous conduits
US4861652A (en) * 1987-10-13 1989-08-29 Kimberly-Clark Corporation Diaper article with elasticized waist panel
US4968297A (en) * 1989-05-09 1990-11-06 Iomec, Inc. Iontophoretic electrode with solution containment system
US5015228A (en) * 1989-06-05 1991-05-14 Eastman Kodak Company Sterilizing dressing device and method for skin puncture
FR2658082B1 (en) * 1990-02-15 1995-06-09 Metais Joel Improvements in implantable vascular access devices.
US5176662A (en) * 1990-08-23 1993-01-05 Minimed Technologies, Ltd. Subcutaneous injection set with improved cannula mounting arrangement

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4564054A (en) * 1983-03-03 1986-01-14 Bengt Gustavsson Fluid transfer system
US5269765A (en) * 1992-03-10 1993-12-14 Injectimed, Inc. Methods of manufacture of safety sleeves for medical injection devices

Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853399A (en) * 1995-05-26 1998-12-29 Sasaki; Hiroshi Medical instruments and systems for puncturing an organ
US5882331A (en) * 1995-05-26 1999-03-16 Sasaki; Hiroshi Methods for puncturing an organ within a body cavity
US5728071A (en) * 1996-09-09 1998-03-17 Watson; Robert L. Injection patch
US5993423A (en) * 1998-08-18 1999-11-30 Choi; Soo Bong Portable automatic syringe device and injection needle unit thereof
US5971963A (en) * 1998-08-18 1999-10-26 Choi; Soo Bong Portable automatic syringe device and injection needle unit thereof
US5993411A (en) * 1998-08-18 1999-11-30 Choi; Soo Bong Portable automatic syringe device and injection needle unit thereof
US6796967B2 (en) 2001-10-22 2004-09-28 Nps Pharmaceuticals, Inc. Injection needle assembly
US8221386B2 (en) 2002-07-02 2012-07-17 Patton Medical Devices, Lp Method relating to infusion device
US8777925B2 (en) 2002-07-02 2014-07-15 Medtronic Minimed, Inc. Methods relating to infusion device
US9486575B2 (en) 2002-07-02 2016-11-08 Medtronic Minimed, Inc. Infusion device
US20060217659A1 (en) * 2002-07-02 2006-09-28 Patton Catherine C Infusion devices
US20060264818A1 (en) * 2002-07-02 2006-11-23 Patton Catherine C Infusion device
US20060264900A1 (en) * 2002-07-02 2006-11-23 Patton Catherine C Method relating to infusion device
US20070049874A1 (en) * 2002-07-02 2007-03-01 Patton Catherine C Infusion Device
US20070049875A1 (en) * 2002-07-02 2007-03-01 Patton Catherine C Infusion Device
US20070049876A1 (en) * 2002-07-02 2007-03-01 Patton Catherine C Infusion Device
US20070049877A1 (en) * 2002-07-02 2007-03-01 Patton Catherine C Infusion Device
US20070093757A1 (en) * 2002-07-02 2007-04-26 Patton Catherine C Infusion Device
US8366683B2 (en) 2002-07-02 2013-02-05 Patton Medical Devices, Lp Infusion devices
US8262627B2 (en) 2002-07-02 2012-09-11 Patton Medical Devices, Lp Infusion device
US20040006316A1 (en) * 2002-07-02 2004-01-08 Patton Catherine C. Infusion device and method thereof
US20080172034A1 (en) * 2002-07-02 2008-07-17 Patton Catherine C Methods Relating To Infusion Device
US7524300B2 (en) 2002-07-02 2009-04-28 Patton Medical Devices, Lp Infusion device
US20090118674A1 (en) * 2002-07-02 2009-05-07 Patton Catherine C Infusion Devices
US7704228B2 (en) 2002-07-02 2010-04-27 Patton Medical Devices, Lp Infusion device
US7731680B2 (en) 2002-07-02 2010-06-08 Patton Medical Devices, Lp Infusion device
US7935090B2 (en) 2002-07-02 2011-05-03 Patton Medical Devices, Lp Infusion device
US8221361B2 (en) 2002-07-02 2012-07-17 Patton Medical Devices, Lp Infusion devices
US8216208B2 (en) 2002-07-02 2012-07-10 Patton Medical Devices, Lp Method relating to infusion device
US7338465B2 (en) 2002-07-02 2008-03-04 Patton Medical Devices, Lp Infusion device and method thereof
US8221362B2 (en) 2002-07-02 2012-07-17 Patton Medical Devices, Lp Infusion device
US8376998B2 (en) 2003-09-17 2013-02-19 Elcam Medical Agricultural Cooperative Association Ltd. Automatic injection device
EP2650033A2 (en) 2003-09-17 2013-10-16 Elcam Medical Agricultural Cooperative Association Ltd. Automatic injection device
US7985216B2 (en) 2004-03-16 2011-07-26 Dali Medical Devices Ltd. Medicinal container engagement and automatic needle device
WO2005118053A2 (en) * 2004-05-26 2005-12-15 Kriesel Marshall S Fluid delivery device
WO2005118053A3 (en) * 2004-05-26 2006-03-30 Marshall S Kriesel Fluid delivery device
US20080021375A1 (en) * 2005-08-22 2008-01-24 John Burns Fluid Delivery Devices, Systems and Methods
US8551047B2 (en) 2005-08-22 2013-10-08 Patton Medical Devices, Lp Fluid delivery devices, systems and methods
US8226614B2 (en) 2005-11-03 2012-07-24 Patton Medical Devices, Lp Fluid delivery devices, systems and methods
US9039660B2 (en) 2005-11-03 2015-05-26 Medtronic Minimed, Inc. Fluid delivery devices, systems and methods
US20070135774A1 (en) * 2005-11-03 2007-06-14 Patton Medical Devices, Lp Fluid delivery devices, systems and methods

Also Published As

Publication number Publication date Type
CA2141448A1 (en) 1995-02-18 application
EP0678041A4 (en) 1996-03-27 application
FI951755A0 (en) 1995-04-12 application
JPH08505080A (en) 1996-06-04 application
EP0678041A1 (en) 1995-10-25 application
US5342319A (en) 1994-08-30 grant
CA2141448C (en) 1999-09-07 grant
FI951755D0 (en) grant
FI951755A (en) 1995-04-12 application
WO1995005858A3 (en) 1995-04-27 application
WO1995005858A2 (en) 1995-03-02 application

Similar Documents

Publication Publication Date Title
US3335723A (en) Indwelling catheter unit
US3134380A (en) Shielded hypodermic needle
US5411499A (en) Needleless vial access device
US5312366A (en) Shielded cannula assembly
US5102393A (en) Autoinjector converted from intramuscular to subcutaneous mode of injection
US4988339A (en) Retractable needle/syringe devices for blood collection, catheterization, and medicinal injection procedures
US6298541B1 (en) Method for making a safety shield assembly and related combinations thereof
US5024616A (en) Disposable sheath for hypodermic cannula used with a syringe
US6796967B2 (en) Injection needle assembly
US5067948A (en) Safety, packaging, injection and disposal system for pre-filled pharmaceutical vials
US4894054A (en) Preloaded automatic disposable syringe
US4964866A (en) Needle sheath assembly
US5832971A (en) Syringe filling and delivery device
US4850961A (en) Indwelling placement device with guard
US5080654A (en) Fluid injection device for intravenous delivery system
US6632198B2 (en) Retracting needle syringe
US5279582A (en) Retractable syringe sheath with bottle engagement
US5167643A (en) Needle protection station
US5527306A (en) Vial adapter
US7396346B2 (en) Indwelling catheter set
US5139483A (en) Medical intravenous administration line connector
US5848990A (en) Device for introducing active substance into a patient
US5928200A (en) Self retracting medical needle apparatus and methods
US6440104B1 (en) Safety shield assembly
US5656031A (en) Medical syringe and self retracting needle apparatus

Legal Events

Date Code Title Description
FPAY Fee payment

Year of fee payment: 4

REMI Maintenance fee reminder mailed
LAPS Lapse for failure to pay maintenance fees
FP Expired due to failure to pay maintenance fee

Effective date: 20030425