US3975417A - Process for producing halogenated organotin compounds - Google Patents

Process for producing halogenated organotin compounds Download PDF

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US3975417A
US3975417A US05/516,868 US51686874A US3975417A US 3975417 A US3975417 A US 3975417A US 51686874 A US51686874 A US 51686874A US 3975417 A US3975417 A US 3975417A
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alcohol
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metallic tin
chloride
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US05/516,868
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Seiji Sagawa
Osamu Kimura
Kenji Sekimori
Fumiyuki Ito
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Kyodo Chemical Co Ltd
Sumitomo Chemical Co Ltd
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Kyodo Chemical Co Ltd
Sumitomo Chemical Co Ltd
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Priority claimed from JP7810972A external-priority patent/JPS525483B2/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22Tin compounds
    • C07F7/2208Compounds having tin linked only to carbon, hydrogen and/or halogen

Definitions

  • the present invention relates to a method for preparing halogenated organotin compounds, namely n-octyltin chlorides.
  • halogenated organotin compounds are important intermediates. For example, they are hydrolyzed by a known method to give corresponding organotin oxides, which are useful for the production of various stabilizers for halogen-containing synthetic resins such as polyvinyl chloride.
  • halogenated alkyltin compounds e.g. the Grignard Method, the Wultz Method and the like, are known, amd among them the most convenient and economically advantageous methods are those in which halogenated compounds are reacted directly with metallic tin.
  • the inventors as a result of extensive studies on avoiding these defects, have surprisingly found that the objective products can be obtained, even if chlorides or bromides are employed as the alkylating agent, in a short time and at a high yield as could never be imagined from conventional knowledge, by adding to the reaction system a nitrogen-containing phosphorus compound or a mixture of a phosphorus compound and an amine compound, and in addition a small amount of at least one member selected from the group consisting of bromine, iodine and compounds thereof.
  • the present invention thus provides a process for producing an octyltin chloride of the formula
  • m is an integer of 1 to 3, which comprises reacting n-octyl chloride with metallic tin in an organic solvent in the presence of (1) a mixture of a phosphorus compound with an amine compound, or a phosphorus compound having a nitrogen atom in the molecule, and (2) at least one member of bromine, a bromine compound, iodine and an iodine compound.
  • phosphorus compounds of the present invention are included: triphenyl phosphate, triphenyl phosphite, diphenyl phosphorochloridate, triethyl phosphite, tributyl phosphite and tetraethylphosphonium iodide. Of these, the most favorable is triphenyl phosphite.
  • N-methyl pyrrolidone As the amine compounds used together with the above said phosphorus compounds, the following compounds are included: N-methyl pyrrolidone, quinoline, morpholine, pyridine, dibutylamine, tributylamine, triphenylamine and N,N-dimethylformamide. Of these, the most favorable is N-methyl pyrrolidone.
  • nitrogen-containing phosphorus compounds of the present invention there are included hexamethylphosphoramide, dimethylphosphoramidic dichloride and tetramethylphosphoramidic chloride. Of these, the most favorable is hexamethylphosphoramide.
  • bromine and iodine compounds of the present invention the following compounds are included: inorganic bromine and iodine compounds which are capable of evolving bromine or iodine at the reaction temperature employed, for example, PBr 3 , AlBr 3 , CuI 2 , MgI 2 , MgBr 2 , ZnBr 2 and ZnI 2 .
  • the organic solvents used in the present process include the following alcohols: n-butyl alcohol, methoxybutyl alcohol, 2-ethylhexyl alcohol, n-octyl alcohol, decyl alcohol and lauryl alcohol. Of these, the favorable ones n-butyl alcohol, 2-ethylhexyl alcohol and n-octyl alcohol.
  • the amount of n-octyl chloride employed according to the present invention is 1.5 to 5 times by molar ratio based on metallic tin, preferably 2 to 3 times.
  • the reaction is carried out at 130° to 230°C. for 3 to 20 hours under atmospheric or increased pressure, whereby the reaction is completed and the rate of conversion of tin amounts to approximately 100 %.
  • the mixture of the amine compound and the phosphorus compound, or the nitrogen-containing phosphorus compound is each used in an amount of at least 0.1% by weight based on the metallic tin, e.g. 0.001 g. to 1.5 g., preferably 0.05 to 1 g., per 1 g.
  • tin, and bromine, iodine or compounds thereof is each used in an amount of at least 0.01% by weight based on the metallic tin, e.g. 0.0001 g. to g., preferably 0.001 to 0.2 g., per 1 g. of tin.
  • the solvent is used usually in an amount of 0.1 to 2.0 g., preferably 0.17 to 1.7 g., per 1 g. of tin.
  • any one of mono-, di- or tri-octyltin compounds in a relatively large amount by changing the amount of phosphorus compounds, amine compounds, nitrogen-containing phosphorus compounds and the organic solvents.
  • more favorable mono- or di-octyltin chloride can selectively be obtained by controlling the amount of organic solvents.
  • the organic solvents of the present invention also function as an alkylating catalyst as shown in examples hereinafter, and therefore the use thereof is essential. And the reaction system where organic solvents alone and no phosphorus compounds are used has a disadvantage that a tin reaction does not substantially proceed. Bromine, iodine or compounds thereof act particularly effectively as an initiator of the tin reaction.
  • the phosphorus compounds and the amine compounds of the present invention do not show so highly a catalytic effect when used separately, but show an extremely high synergistic effect when used in combination, and bromine, iodine and compounds thereof are especially effective as an initiator of the tin reaction. Therefore the lack of any one of the above-mentioned conditions can not permit the reaction to proceed completely.
  • the mixture is distilled under a reduced pressure to recover n-octylchloride, n-octanol and hexamethylphosphoramide which are present in excess, and heated while stirring at 90°C. to 100°C. for 30 minutes with the addition of 100 ml. of conc. hydrochloric acid.
  • the resulting layer of hydrochloric acid is separated to remove inorganic tin compounds therefrom.
  • the mixture of octyltinchlorides thus obtained is separated by a known chemical separation process to give 45.5 % of octyltintrichloride, 38.1 % of dioctyltindichloride and 11.2 % of trioctyltinchloride, the total yield of those three compounds really amounting 94.8 % based on the metallic tin employed.
  • the metallic tin does not show any change even when heated at 180°C. for 20 hours.
  • n-octylalcohol is not added, the rate of conversion of tin alone reaches 100 %, however 0 %, 21.3 % and 27.7 % of metallic tin employed are only consumed to produce monooctyltintrichloride, dioctyltindichloride and trioctyltinchloride respectively, the total yield amounting to only 49.0 %.
  • tin foil 94.2 g. of n-octylchloride, 8.5 g. of hexamethylphosphoramide, 50 g. of n-octanol and 2 g. of iodine are placed in the same apparatus as used in Example 1, heated under reflux at 180° to 185°C. for 10 hours, then 100 % of the tin foil is reacted.
  • monooctyltintrichloride, dioctyltindichloride and trioctyltinchloride are obtained in the yields of 69.5 %, 20.0 % and 6.3 % respectively, the total yield being 95.8 %.
  • tin foil 94.2 g. of n-octylchloride, 2.5 g. of hexamethylphosphoramide, 5 g. of n-octanol and 2 g. of iodine are placed in the same apparatus as used in Example 1, heated under reflux at 180° to 190°C. for 4 hours, then 100 % of the tin foil is reacted.
  • monooctyltintrichloride, dioctyltindichloride and trioctyltinchloride are obtained in the yields of 10.0 %, 35.5 % and 51.2 % respectively, the total yield being 96.7 %.
  • tin foil 95 g. of n-octylchloride, 10 g. of triphenylphosphate, 40 g. of N-methyl pyrrolidone, 20 g. of n-octyl alcohol and 2 g. of iodine are placed in a 500 ml. flask with four necks equipped with a stirrer, a reflux condenser and a thermometer, heated under reflux at 185° to 190°C. for 6 hours, then 100 % of the tin foil is reacted to give a yellow clear reaction mixture.
  • the mixture is treated by a known chemical purification procedure to give octyltintrichloride, dioctyltindichloride and trioctyltinchloride in the yields of 43.9 %, 42.1 % and 10.1 % respectively.
  • the total yield of those three octyltinchlorides amounts to 95.2 % based on the metallic tin employed.

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  • Organic Chemistry (AREA)
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Abstract

A process for the production of an octyltin chloride of the formula, (N-C8H17)m SnCl4-m WHEREIN M IS AN INTEGER OF 1 TO 3, WHICH COMPRISES REACTING N-OCTYL CHLORIDE WITH METALLIC TIN IN AN ORGANIC SOLVENT IN THE PRESENCE OF (1) EITHER A MIXTURE OF A PHOSPHORUS COMPOUND WITH AN AMINE, OR A PHOSPHORUS COMPOUND HAVING A NITROGEN ATOM IN THE MOLECULE, AND (2) AT LEAST ONE OF BROMINE, A BROMINE COMPOUND, IODINE AND AN IODINE COMPOUND. The octyltin chlorides are useful for the production of stabilizers for polyvinyl chloride.

Description

This application is a continuation-in-part of copending application, Ser. No. 354,138, filed on Apr. 24, 1973, now abandoned.
The present invention relates to a method for preparing halogenated organotin compounds, namely n-octyltin chlorides.
The halogenated organotin compounds are important intermediates. For example, they are hydrolyzed by a known method to give corresponding organotin oxides, which are useful for the production of various stabilizers for halogen-containing synthetic resins such as polyvinyl chloride.
A number of methods for preparing halogenated alkyltin compounds, e.g. the Grignard Method, the Wultz Method and the like, are known, amd among them the most convenient and economically advantageous methods are those in which halogenated compounds are reacted directly with metallic tin.
Methods for obtaining halogenated alkyltin compounds by using alkyl iodides as an alkylating agent have already been accomplished as an industrial process.
However, as this method needs the use of expensive alkyl iodides, the recovery of iodine is economically indispensable, and moreover, the yields of alkyltin iodides having a long-chain alkyl group having above 8 carbon atoms are only at best approximately 80%.
For the above reason, a development of the process has so far been desired in which objective products can be obtained in a high yield by using low-priced chlorides as an alkylating agent.
Many compounds, however, which have been considered to be an effective catalyst in a direct reaction of alkyl iodides with metallic tin are substantially of no effect in reactions of corresponding bromides or chlorides with metallic tin, and therefore the reactions proceed with extreme difficulty, and the rate of conversion of metallic tin into organotin compounds, particularly when chlorides are employed, is quite low except for a very few activated chlorides, e.g. benzylchloride.
The inventors, as a result of extensive studies on avoiding these defects, have surprisingly found that the objective products can be obtained, even if chlorides or bromides are employed as the alkylating agent, in a short time and at a high yield as could never be imagined from conventional knowledge, by adding to the reaction system a nitrogen-containing phosphorus compound or a mixture of a phosphorus compound and an amine compound, and in addition a small amount of at least one member selected from the group consisting of bromine, iodine and compounds thereof.
The present invention thus provides a process for producing an octyltin chloride of the formula,
(n--C.sub.8 H.sub.17).sub.m SnCl.sub.4-m
wherein m is an integer of 1 to 3, which comprises reacting n-octyl chloride with metallic tin in an organic solvent in the presence of (1) a mixture of a phosphorus compound with an amine compound, or a phosphorus compound having a nitrogen atom in the molecule, and (2) at least one member of bromine, a bromine compound, iodine and an iodine compound.
In carrying out the process of the present invention, as concrete examples of phosphorus compounds of the present invention, the following compounds are included: triphenyl phosphate, triphenyl phosphite, diphenyl phosphorochloridate, triethyl phosphite, tributyl phosphite and tetraethylphosphonium iodide. Of these, the most favorable is triphenyl phosphite.
As the amine compounds used together with the above said phosphorus compounds, the following compounds are included: N-methyl pyrrolidone, quinoline, morpholine, pyridine, dibutylamine, tributylamine, triphenylamine and N,N-dimethylformamide. Of these, the most favorable is N-methyl pyrrolidone.
As the nitrogen-containing phosphorus compounds of the present invention, there are included hexamethylphosphoramide, dimethylphosphoramidic dichloride and tetramethylphosphoramidic chloride. Of these, the most favorable is hexamethylphosphoramide.
Furthermore, as bromine and iodine compounds of the present invention, the following compounds are included: inorganic bromine and iodine compounds which are capable of evolving bromine or iodine at the reaction temperature employed, for example, PBr3, AlBr3, CuI2, MgI2, MgBr2, ZnBr2 and ZnI2.
The organic solvents used in the present process, which also function as an alkylating catalyst, include the following alcohols: n-butyl alcohol, methoxybutyl alcohol, 2-ethylhexyl alcohol, n-octyl alcohol, decyl alcohol and lauryl alcohol. Of these, the favorable ones n-butyl alcohol, 2-ethylhexyl alcohol and n-octyl alcohol.
The amount of n-octyl chloride employed according to the present invention is 1.5 to 5 times by molar ratio based on metallic tin, preferably 2 to 3 times. The reaction is carried out at 130° to 230°C. for 3 to 20 hours under atmospheric or increased pressure, whereby the reaction is completed and the rate of conversion of tin amounts to approximately 100 %. The mixture of the amine compound and the phosphorus compound, or the nitrogen-containing phosphorus compound is each used in an amount of at least 0.1% by weight based on the metallic tin, e.g. 0.001 g. to 1.5 g., preferably 0.05 to 1 g., per 1 g. of tin, and bromine, iodine or compounds thereof is each used in an amount of at least 0.01% by weight based on the metallic tin, e.g. 0.0001 g. to g., preferably 0.001 to 0.2 g., per 1 g. of tin.
The solvent is used usually in an amount of 0.1 to 2.0 g., preferably 0.17 to 1.7 g., per 1 g. of tin.
According to the process of the present invention, it is possible to optionally obtain any one of mono-, di- or tri-octyltin compounds in a relatively large amount by changing the amount of phosphorus compounds, amine compounds, nitrogen-containing phosphorus compounds and the organic solvents. For example, more favorable mono- or di-octyltin chloride can selectively be obtained by controlling the amount of organic solvents.
The organic solvents of the present invention also function as an alkylating catalyst as shown in examples hereinafter, and therefore the use thereof is essential. And the reaction system where organic solvents alone and no phosphorus compounds are used has a disadvantage that a tin reaction does not substantially proceed. Bromine, iodine or compounds thereof act particularly effectively as an initiator of the tin reaction.
The phosphorus compounds and the amine compounds of the present invention do not show so highly a catalytic effect when used separately, but show an extremely high synergistic effect when used in combination, and bromine, iodine and compounds thereof are especially effective as an initiator of the tin reaction. Therefore the lack of any one of the above-mentioned conditions can not permit the reaction to proceed completely.
The present invention will now be illustrated in detail with reference to examples which are illustrative but not limitative thereto.
EXAMPLE 1
30 g. of tin foil, 94.2 g. of n-octylchloride, 25 g. of hexamethylphosphoramide, 25 g. of n-octanol and 2 g. of iodine are placed in a 500 ml. flask with four necks equipped with a stirrer, a reflux condenser and a thermometer, heated under reflux at 170° to 185°C. for 4 hours, then 100 % of the tin foil is reacted to give a yellow clear reaction mixture. The mixture is distilled under a reduced pressure to recover n-octylchloride, n-octanol and hexamethylphosphoramide which are present in excess, and heated while stirring at 90°C. to 100°C. for 30 minutes with the addition of 100 ml. of conc. hydrochloric acid. The resulting layer of hydrochloric acid is separated to remove inorganic tin compounds therefrom. The mixture of octyltinchlorides thus obtained is separated by a known chemical separation process to give 45.5 % of octyltintrichloride, 38.1 % of dioctyltindichloride and 11.2 % of trioctyltinchloride, the total yield of those three compounds really amounting 94.8 % based on the metallic tin employed.
When the above reaction is carried out without adding thereto hexamethylphosphoramide or iodine, the metallic tin does not show any change even when heated at 180°C. for 20 hours. When n-octylalcohol is not added, the rate of conversion of tin alone reaches 100 %, however 0 %, 21.3 % and 27.7 % of metallic tin employed are only consumed to produce monooctyltintrichloride, dioctyltindichloride and trioctyltinchloride respectively, the total yield amounting to only 49.0 %.
EXAMPLE 2
30 g. of tin foil, 94.2 g. of n-octylchloride, 8.5 g. of hexamethylphosphoramide, 50 g. of n-octanol and 2 g. of iodine are placed in the same apparatus as used in Example 1, heated under reflux at 180° to 185°C. for 10 hours, then 100 % of the tin foil is reacted. After the same procedure as given in Example 1, monooctyltintrichloride, dioctyltindichloride and trioctyltinchloride are obtained in the yields of 69.5 %, 20.0 % and 6.3 % respectively, the total yield being 95.8 %.
EXAMPLE 3
30 g. of tin foil, 94.2 g. of n-octylchloride, 2.5 g. of hexamethylphosphoramide, 5 g. of n-octanol and 2 g. of iodine are placed in the same apparatus as used in Example 1, heated under reflux at 180° to 190°C. for 4 hours, then 100 % of the tin foil is reacted. After the same procedure as given in Example 1, monooctyltintrichloride, dioctyltindichloride and trioctyltinchloride are obtained in the yields of 10.0 %, 35.5 % and 51.2 % respectively, the total yield being 96.7 %.
EXAMPLES 4-21
The products and yields thereof which are obtained by reacting, at 180°C. to 190°C., 30 g. of tin foil with 94.2 g. of n-octyl chloride in the presence of materials in the proportion given in Table I are summarized in the Table.
Compounds of the general formula Rm SnX4-m in which m is equal to 4 cannot be obtained in any one of Examples.
                                  Table I                                 
__________________________________________________________________________
                                           Rate of                        
                                                Yields of                 
Ratio of amount of compounds used          conver-                        
                                                R.sub.m SnX.sub.4-m       
Ex. Nitrogen-containing                                                   
                 Organic   Br.sub.2, I.sub.2 or                           
                                      Reaction                            
                                           sion of                        
                                                (%)                       
No. phosphorus compounds                                                  
                 solvents  compounds  time tin                            
             (g.)     (g.) thereof                                        
                                  (g.)                                    
                                      (hr.)                               
                                           (%)  m=1  m=2  m=3             
__________________________________________________________________________
4   Hexamethylphos-                                                       
             25  n-octyl    I.sub.2                                       
                                  2   4    100  45.5 38.1 11.2            
    phoramide    alcohol                                                  
                      25                                                  
5   Dimethylphos-                                                         
             25   "   25    "     2   4    100  43.8 37.9 12.4            
    phoramidic                                                            
    dichloride                                                            
6   Hexamethyl-                                                           
              8.5                                                         
                  "   50    "     2   10   100  69.5 20.0  6.3            
    phosphoramide                                                         
7     "       2.5                                                         
                  "    5    "     2   4    100  10.0 35.5 51.2            
8   Tetramethyl-                                                          
             25   "   10    "     1   5    100  18   55   18              
    phosphoramide                                                         
    chloride                                                              
9   Hexamethyl-                                                           
             25  2-ethyl-                                                 
                      10    "     1   4    100  21   51   20              
    phosphoramide                                                         
                 hexyl                                                    
                 alcohol                                                  
                 methoxy-                                                 
10    "      25  butyl                                                    
                      20    "     1   9    100  18   62   10              
                 alcohol                                                  
11    "      25  lauryl                                                   
                      20    "     1   5    100  18   67    6              
                 alcohol                                                  
12  Hexamethyl-                                                           
             25  n-octyl                                                  
                       5    PBr.sub.3                                     
                                  4   12   100   4   73   17              
    phosphoramide                                                         
                 alcohol                                                  
13    "      25   "    5    Br.sub.2                                      
                                  5   15   100   3   71   16              
14    "      15   "    5    CuI.sub.2                                     
                                  4   14   100   5   70   15              
15    "      25  2-ethyl-                                                 
                      25    I.sub.2                                       
                                  2   4    100  40.2 46.2  9.4            
                 hexyl                                                    
                 alcohol                                                  
16    "      25  lauryl                                                   
                      25    "     2   4    100  35.7 50.6  8.4            
                 alcohol                                                  
17    "      15  n-octyl                                                  
                      15    "     2   5    100  20.5 56.1 19.2            
                 alcohol                                                  
18    "      10   "   15    "     2   8    100  18.5 58.3 19.2            
19  Tetramethyl-                                                          
             25   "   15    "     2   5    100  19.7 55.3 21.4            
    phosphoramidic                                                        
    chloride                                                              
20  Dimethylphos-                                                         
             25  methoxy-                                                 
                      15    "     2   6    100  22.0 49.2 20.6            
    phoamidic    butyl                                                    
    dichloride   alcohol                                                  
21    "      25  n-octyl                                                  
                      15    "     2   6    100  21.2 52.0 21.4            
                 alcohol                                                  
__________________________________________________________________________
EXAMPLE 22
30 g. of tin foil, 95 g. of n-octylchloride, 10 g. of triphenylphosphate, 40 g. of N-methyl pyrrolidone, 20 g. of n-octyl alcohol and 2 g. of iodine are placed in a 500 ml. flask with four necks equipped with a stirrer, a reflux condenser and a thermometer, heated under reflux at 185° to 190°C. for 6 hours, then 100 % of the tin foil is reacted to give a yellow clear reaction mixture. The mixture is treated by a known chemical purification procedure to give octyltintrichloride, dioctyltindichloride and trioctyltinchloride in the yields of 43.9 %, 42.1 % and 10.1 % respectively. The total yield of those three octyltinchlorides amounts to 95.2 % based on the metallic tin employed.
EXAMPLES 23-37
The results of Examples 23-37 which are carried out according to Examples mentioned above are summarized in Table II in which 94.2 g. of n-octyl chloride is used, and the metallic tin employed is tin foil in all cases in an amount of 30 g. Compounds of the general formula
R.sub.m SnX.sub.4-m
in which m is equal to 4 cannot be obtained in any one of the Examples.
                                  Table II                                
__________________________________________________________________________
                                              Rate of                     
                                                   Yields of              
Ratio of amount of compounds              Reac-                           
                                              conver-                     
                                                   R.sub.m SnX.sub.4-m    
Ex.                                                                       
   Organic   Phosphorus                                                   
                      Amine     Br.sub.2, I.sub.2 or                      
                                          tion                            
                                              sion of                     
                                                   (%)                    
No.                                                                       
   solvents  compounds                                                    
                      compounds compounds time                            
                                              tin                         
          (g.)     (g.)      (g.)                                         
                                thereof                                   
                                       (g.)                               
                                          (hr.)                           
                                              (%)  m=1 m=2 m=3            
__________________________________________________________________________
23 n-octyl                                                                
          10 triphenyl                                                    
                   10 N-methyl                                            
                             40  I.sub.2                                  
                                       2  4   100  18.0                   
                                                       68.8               
                                                            9.6           
   alcohol   phosphite                                                    
                      pyrrolidone                                         
24 lauryl  5 diphenyl                                                     
                   10   "    40  "     2  4   100  13.4                   
                                                       71.5               
                                                            9.9           
   alcohol   phosphor-                                                    
             chloridate                                                   
25 n-octyl                                                                
           5 triethyl                                                     
                   10   "    40 AlBr.sub.3                                
                                       4  4   100  10.5                   
                                                       73.7               
                                                           10.1           
   alcohol   phosphite                                                    
26 2-ethyl-                                                               
           5  "    10   "    40 CuI.sub.2                                 
                                       4  4   100  12.0                   
                                                       78.5               
                                                            5.0           
   hexyl                                                                  
   alcohol                                                                
27 n-butyl                                                                
          40  "     5   "    40  I.sub.2                                  
                                       2  4   100  45.0                   
                                                       45.5               
                                                            5.3           
   alcohol                                                                
28 2-ethylhexyl                                                           
          10 triphenyl                                                    
                   20 quinoline                                           
                             20 PBr.sub.3                                 
                                       5  3   100  10.9                   
                                                       45.0               
                                                           34.8           
   alcohol   phosphite                                                    
29   "    10  "    20 morpholine                                          
                             20 MgI.sub.2                                 
                                       5  4   100  12.3                   
                                                       39.9               
                                                           36.9           
30 decyl  10  "    20 tributyl-                                           
                             20 MgBr.sub.2                                
                                       5  3   100  11.8                   
                                                       39.2               
                                                           40.4           
   alcohol            amine                                               
31 methoxybutyl                                                           
          10  "    20 triphenyl-                                          
                             20 Br.sub.2                                  
                                       5  3   100  13.2                   
                                                       38.0               
                                                           39.0           
   alcohol            amine                                               
32 2-ethylhexyl                                                           
          10 diphenyl                                                     
                   10 pyridine                                            
                             20 ZnBr.sub.2                                
                                       5  3   100  11.6                   
                                                       40.2               
                                                           38.3           
   alcohol   phosphor-                                                    
             chloridate                                                   
33 lauryl 10 tetraethyl                                                   
                   20 N,N-di-                                             
                             20 ZnI.sub.2                                 
                                       4  4   100  12.7                   
                                                       35.6               
                                                           40.6           
   alcohol   phosphonium                                                  
                      methyl-                                             
             iodide   formamide                                           
34 methoxybutyl                                                           
           5 triphenyl                                                    
                   20 tributyl-                                           
                             20  I.sub.2                                  
                                       2  4   100  12.0                   
                                                       41.0               
                                                           37.0           
   alcohol   phosphite                                                    
                      amine                                               
35 2-ethylhexyl                                                           
          25 triphenyl                                                    
                   20   "    20  "     2  3   100  36.2                   
                                                       40.0               
                                                           15.3           
   alcohol   phosphate                                                    
36 n-octyl                                                                
           5  "    20   "    20  "     2  5   100  12.6                   
                                                       41.0               
                                                           36.5           
   alcohol                                                                
37 methoxybutyl                                                           
          25  "    20   "    20  "     2  3   100  34.9                   
                                                       48.1               
                                                            6.2           
   alcohol                                                                
__________________________________________________________________________

Claims (6)

What is claimed is:
1. A process for producing an octyltin chloride of the formula
(n-C.sub.8 H.sub.17).sub.m SnCl.sub.4-m
wherein m is an integer of 1 to 3, which comprises reacting n-octyl chloride with metallic tin in the presence of, as a first component, (1) a mixture of (a) a phosphorus compound selected from the group consisting of triethyl phosphite, tributyl phosphite, triphenyl phosphite, triphenyl phosphate, diphenyl phosphorchloridate and tetraethylphosphonium iodide, with (b) an amine compound selected from the group consisting of N-methyl pyrrolidone, quinoline, morpholine, pyridine, dibutylamine, tributylamine, triphenylamine and N,N-dimethylformamide, or (2) a nitrogen-containing phosphorus compound selected from the group consisting of hexamethylphosphoramide, dimethylphosphoramidic dichloride and tetramethylphosphoramidic chloride, together with, as a second component, at least one member selected from the group consisting of bromine, iodine, PBr3, AlBr3, CuI2, MgI2, MgBr2, ZnBr2 and ZnI2 which are capable of evolving bromine or iodine at the reaction temperature employed, and as a third component, an organic solvent selected from the group consisting of n-butyl alcohol, methoxybutyl alcohol, 2-ethylhexyl alcohol, n-octyl alcohol, decyl alcohol and lauryl alcohol.
2. The process according to claim 1, wherein the reaction is carried out at a temperature of from 130°C. to 230°C. for from 3 to 20 hours.
3. The process according to claim 1, wherein the n-octyl chloride is used in an amount of 1.5 to 5 moles per mol of metallic tin.
4. The process according to claim 1, wherein the mixture of the phosphorus compound with the amine compound is used in an amount of at least 0.1% by weight based on the amount of metallic tin.
5. The process according to claim 1, wherein the nitrogen-containing phosphorus compound is used in an amount of at least 0.1% by weight based on the amount of metallic tin.
6. The process according to claim 1, wherein the second component is used in an amount of at least 0.01% by weight based on the amount of metallic tin.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510095A (en) * 1982-01-07 1985-04-09 Manchem Limited Production of organotin halides
US4658046A (en) * 1985-07-08 1987-04-14 Zemex Corporation Process for the preparation of methyltin chlorides
WO2005118600A3 (en) * 2004-05-28 2006-02-16 Baerlocher Italia S P A Process for the preparation of hydrocarbyl metal halides, especially alkyl tin halides

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US3340283A (en) * 1964-05-20 1967-09-05 M & T Chemicals Inc Preparation of organotin-trihalides
US3387012A (en) * 1964-09-12 1968-06-04 Jasching Wolfgang Production of dialiphatic tind dihalides
US3404167A (en) * 1964-11-30 1968-10-01 Argus Chem Process for preparing organotin halides
US3414595A (en) * 1964-08-27 1968-12-03 Pure Chem Ltd Preparation of alkyl tin compounds
US3440255A (en) * 1967-09-28 1969-04-22 Sumio Matsuda Process for preparing organotin halides
US3519667A (en) * 1968-03-29 1970-07-07 Carlisle Chemical Works Process for preparing mono-methyl or ethyltin trichloride
US3519665A (en) * 1968-01-25 1970-07-07 Carlisle Chemical Works Direct synthesis of dialkyltin dichloride
US3745183A (en) * 1963-04-18 1973-07-10 Nitto Chemical Industry Co Ltd Process for producing alkyl tin halides

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US3745183A (en) * 1963-04-18 1973-07-10 Nitto Chemical Industry Co Ltd Process for producing alkyl tin halides
US3340283A (en) * 1964-05-20 1967-09-05 M & T Chemicals Inc Preparation of organotin-trihalides
US3414595A (en) * 1964-08-27 1968-12-03 Pure Chem Ltd Preparation of alkyl tin compounds
US3387012A (en) * 1964-09-12 1968-06-04 Jasching Wolfgang Production of dialiphatic tind dihalides
US3404167A (en) * 1964-11-30 1968-10-01 Argus Chem Process for preparing organotin halides
US3440255A (en) * 1967-09-28 1969-04-22 Sumio Matsuda Process for preparing organotin halides
US3519665A (en) * 1968-01-25 1970-07-07 Carlisle Chemical Works Direct synthesis of dialkyltin dichloride
US3519667A (en) * 1968-03-29 1970-07-07 Carlisle Chemical Works Process for preparing mono-methyl or ethyltin trichloride

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510095A (en) * 1982-01-07 1985-04-09 Manchem Limited Production of organotin halides
US4658046A (en) * 1985-07-08 1987-04-14 Zemex Corporation Process for the preparation of methyltin chlorides
WO2005118600A3 (en) * 2004-05-28 2006-02-16 Baerlocher Italia S P A Process for the preparation of hydrocarbyl metal halides, especially alkyl tin halides
US20090247775A1 (en) * 2004-05-28 2009-10-01 Andrea Comini Process for the preparation of hydrocarbyl halides
CN101044147B (en) * 2004-05-28 2010-06-02 百尔罗赫意大利有限公司 Process for preparing hydrocarbyl halides

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