US3917063A - Packages enabling the extemporaneous preparation of suspensions or sterile solutions - Google Patents

Packages enabling the extemporaneous preparation of suspensions or sterile solutions Download PDF

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US3917063A
US3917063A US36743773A US3917063A US 3917063 A US3917063 A US 3917063A US 36743773 A US36743773 A US 36743773A US 3917063 A US3917063 A US 3917063A
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Prior art keywords
flask
package
flasks
means
set forth
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Jean Chibret
Charles Manni
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EMBALLAGE ET DE CONDITIONNEMEN
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EMBALLAGE ET DE CONDITIONNEMEN
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089Containers or vials which are to be joined to each other in order to mix their contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D55/00Accessories for container closures not otherwise provided for
    • B65D55/02Locking devices; Means for discouraging or indicating unauthorised opening or removal of closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1406Septums, pierceable membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006Piercing means
    • A61J1/201Piercing means having one piercing end
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/08Mixing

Abstract

A package for the extemporaneous preparation of suspensions or sterile solutions, comprises two flasks at least one of which is of a flexible material and which are adapted respectively to contain one a liquid and the other a solid product to be dissolved in or put into suspension in the liquid at the time of use. Each flask has associated therewith stopper means and the package includes means for temporarily putting the flask interiors into communication with one another through at least one part of said stopper means. Said at least one of the flasks is manually deformable to effect the passage of the liquid from its flask into the flask containing the solid product, and the return into said at least one of said flasks of the resultant solution or suspension.

Description

' United States Patent 1 Chibret et a1.

[ NOV.4,1975

[75] Inventors: Jean Chibret; Charles Manni, both of Fontvieille, Monaco [73] Assignee: Societe dEmballage et de Conditionnement, Fontvieille, Monaco [22] Filed: June 6, 1973 [21] Appl. No.: 367,437

[30] Foreign Application Priority Data June 13, 1972 France 7221179 [52] US. Cl. 206/221; 141/329; 215/DIG. 8; 222/83; 259/60 [51] Int. Cl. B65D 25/08 [58] Field of Search 206/219, 222, 221; 215/6, 2l5/DIG. 8; 259/48, 60; 222/80, 81, 83; 141/329, 330, 348, 349

//I II I/ II 3,206,073 9/1965 Scislowicz 222/80 3,337,039 8/1967 Knittel et a]. 206/221 3,651,990 3/1972 Cernel 206/221 3,720,523 3/1973 Nakagami 206/219 FOREIGN PATENTS OR APPLICATIONS 1,266,052 5/1961 France 206/222 Primary ExaminerWilliam 1. Price Assistant Examiner-Bruce H. Bernstein Attorney, Agent, or FirmMcDougall, Hersh & Scott [57] ABSTRACT A package for the extemporaneous preparation of suspensions or sterile solutions, comprises two flasks at least one of which is of a flexible material and which are adapted respectively to contain one a liquid and the other a solid product to be dissolved in or put into suspension in the liquid at the time of use. Each flask has associated therewith stopper means and the package includes means for temporarily putting the flask interiors into communication with one another through at least-one part of said stopper means. Said at least one of the flasks is manually deformable to effect the passage of the liquid from its flask into the flask containing'the solid product, and the return into said at least one of said flasks of the resultant solution or suspension.

12 Claims, 6 Drawing Figures a a t t 4 a r 1 ,4 5 9 5 1 'J' .1 (a VI: 11 10 8 Irv/ y? 3 g; A3 5 .4 t i a; 2

US. Patent Nov. 4, 1975 Sheet 1 of2 3,917,063

FIG. 2

FlG.1

US. Patent Nov. 4, 1975 Sheet 2 of2 3,917,063

FIG.5

FIG l PACKAGES ENABLING THE EXTEMPORANEOUS PREPARATION OF SUSPENSIONS OR STERILE SOLUTIONS This invention relates to packagesenabling the extemporaneous preparation of suspensions or sterile solutions.

It is already known, especially for enabling the preparation at the instant of use, of ophthalmic drops, to confine the lyophilic material and the liquid to be mixed, separately, the first in a flask and the second in an ampoule, the preparation consisting of opening the flask, decanting therein the contents of the ampoule, and mixing the whole, after having-recorked the flask with a dropper subsequently serving for delivery of the drops.

It is manifest that such a procedure does not permit proper regard to be had for desirable aseptic conditions. Moreover, the operator is compelled to carry out a large number of operations of which each may involve a mistake or a difficulty.

The same holds true in the preparation 'of certain antibiotics for which it is first necessary to inject a liquid into a flask by means of a syringe, then to agitate the flask and to withdraw therefrom the solution or suspension by means of the syringe before injecting the patient, generally after having changed the needle.

The primary object of the invention is to simplify these preparations while paying proper regard to the usual conditions of asepsis.

The present invention is a package comprising two flasks of which at least one is of a flexible material and which are adapted to contain one a liquid and the other a solid product to be dissolved in or put into suspension in said liquid at the time of use, stopper means on each flask and means for temporarily putting the interiors of the two flasks into communication with one another through at least one part of said stopper means, and in which the passage of the liquid from its flask to that of the solid product and the return of the solution or of the suspension to the flask for the liquid may be effected by manual deformation of at least one of the flasks.

This package enables there to be obtained a preparation the sterility of which is perfectly maintained both in use and in keeping in stock.

In a preferred form of the invention, the stopper means on one of the flasks makes up at least partially a device for perforating the stopper means on the other flask.

The invention will be better understood on reading the following description in conjunction with the accompanying drawings which illustrate, by way of example, embodiments of the invention, and in which:

FIG. 1 is a sectional elevation ofa package according to a first embodiment of the invention, in the condition before the two flasks have been put into communication with one another;

FIG. 2 is an exploded sectional elevation of the package shown in FIG. 1;

FIG. 3 is a sectional elevation ofa package according to a second embodiment of the invention in the condition before the two flasks have been put into communication with one another;

FIG. 4 is a sectional elevation of a package according to a third embodiment of the invention in the condition after the two flasks have been put into communication with one another;

FIG. 5 is an exploded sectional elevation of the package shown in FIG. 4, the stopper means and the cover being in the condition before the two flasks have been put into communication with one another; and

FIG. 6 is a sectional elevation of a modified plug for the package shown in FIGS. 4 and 5.

The package of FIGS. 1 and 2 is made up mainly by two flasks l and 2, the flask 1 containing a liquid and the flask 2 containing a solid product. The flask l at least is of a flexible material.

The flask 2 is stopped by a plug 3 of elastomeric material provided with a blind hole 4 located below a membrane 5. A ball 6 is held captive resiliently in the plug 3.

Above the plug is a washer 7 which is impervious to the liquid in the flask 1 and is formed by a polyethylene disk coated on one of its faces with a film of aluminium.

The washer 7 itself has thereabove an internallythreaded tubular casing 8, held in place on the plug 3 with the said washer by a collar 9 flanged around and taking support on the rim of the neck of the bottle 2.

The flask 1 is stopped by a dropper 10 the position of which in the neck of the bottle 1 is limited by a shoulder 11. The flask l is screwed by a thread 12 around its neck into the internally-threaded tubular casing 8.

In its position prior to use, the end of the dropper 10, which is open, rests on the impervious washer 7 and the relative position of the flask 1 dropper l0 assembly with respect to the flask 2 and to the parts which are united therewith is ensured by a tearable or rupturable spacing ring 13 accommodated in a peripheral space between a peripheral external flange 20 around the neck of the flask l, and the adjacent end of the tubular casing 8. As shown in FIGS. 1 "and 2, the spacing ring 13 supports a removable cover 14 which can subsequently be used for covering and protecting the lesser diameter end of the dropper 10.

The package of FIGS. 1 and 2 is used as follows:

the spacer ring 13 is torn and removed,

the flask 1 is screwed into. the tubular casing 8, this occasioning successively puncturings of the washer 7 and of the membrane 5 by the end of the dropper l0 7 and the dropping into the flask of the ball 6 expelled from its seat,

deformation of the flask 1 brings about the passage of its contents into the flask 2,

by agitationof the package, the solution or the desired suspension is obtained. The ball 6 then plays the part of an agitator in the flask 2 and speeds up the obtaining of the preparation,

the package is then inverted and the preparation sucked into the flask l, which is thereafter separated (with its dropper 10) from the flask 2.

After the first use of the preparation, the dropper 10 is covered by the cover 14 detached from the spacer ring 13.

For the description of the embodiments of the invention shown firstly in FIGS. 3 and 4, and secondly in FIG. 5, parts similar to those already described with reference to FIGS. 1 and 2 are designated by the same references but provided with the indices 0 and b, respectively.

The package of FIG. 3 includes two flasks 1a and 2a whereof the former holds a perforating dropper 10a and the latter a plug 3a with a ball 6a, an impervious washer7a and an encasing ring 9a. The initial positioning of the flasks la and 2a is ensuredby a spacing ring 15 whichit isnecessary to tear inorder to enable successively the perforation of the washer 7a and that of the membrane 50 aswell as the dropping of the ball 6a into the receptacle 2a and the stepspof transferring the products, such as have been described with reference to FlGS. l and 2. V

The packageofFlGS. 4 and is made upmainly of.

two flaskslb and 2B whereof the former carries a dropper 1"0b closed at its end by a bulging 16 which can be cut off. The flask 2b is stopped by a plug 3b with a perferable membrane Shanda cover 17 kept on the flask 2b an encasing ring 9b. The cover 17 includes a hemispherical central part 18 which can be cut off just as can the bulged part.16 of the dropper.

In this package the flasks 1b and 2b are initially sepa- 7 rated. At the time of use, the bulged part 1 6 of the dropper 10b' and thehemispherical central part 18 of the cover 17 are cutoff along the respective dot-dash lines'x and y indic ated in FIGS. The extremity of the dropper 10b is then introduced into the remaining part of the cover 17, which ensures guidance of the dropper, and 'the latter pierces the perforable membrane 5b of the plug 3b. The package then being in the condition shown in FIG. 4, it is possible to proceed with the trans-1 fer of the liquid and then the preparation by dcforma tions under consideration; without thereby departing from the scope of the invention defined in the claims.

We claim:

1. A package comprising two flasks of which at least one is of a flexible material and which are adapted to contain one a liquid and the other a solid product which is a'se'lected member of thegroup consisting of substances dissol'vable in and'substances suspendible in said liquid at the time of use, stopper means on each flask and means fortemporarily putting the interiors of the two flasks into communication with one another through at least one part of said stopper means, said at least one of the flasks being manually deformable to effeet the passage ofthe liquid fromits flask into that of the solid product and the return of the solution or of the suspension tothe flask for the liquid, said flasks are kept together in alignment and in readiness for the putting of their contents into communication with each other by spacing means which can be torn away- 2. A package as set forth in claim 1, in which the stopper means on one of the flasks makes up at least partially a device for perforating the stopper means on the other flask.

3. A package as set forth in claim 2, in which said one of the flasks carries a dropper having a projecting end adapted for perforations of the stopper means of the other of the flasks.

4. A package as set forth in claim 3, in which the stopper means of said other of the flasks comprises a plug of'elastomeric material held in the neck of the flask and having an axial bore stopped by means which canbe overcome by said dropper projecting end.

5. A package as set forth in claim 4, in which said means which can be overcome is an ejectable ball.

6. A package as set forth in claim 4, in which said means which can beovercome is a perforable membrane.

7. A package as set forthv in claim 4, in which said means which can be overcome consists of an ejectable ball and a perforable membrane.

8. A package as set forth in claim 7, in which the plug has thereabove a washer which is impervious to the liquid and is formed by a polyethylene disk coated .on one of its faces with a film of aluminium.

9. A package as set forth in claim 4, in which said plug has thereabove a cover which includes a hemispherical central part located in alignment with said, axial bore and which can be cut off at the time. of use,

said cover being retained on the plug by an encasing ring onthe rim of the neck of the flask. i

10. The package of claim 3 further including removable means for preventing the projecting end of said dropper from perforating the stopper of the other flask.

11. A package as set forth in claim 1, wherein one flask is adapted to be displaced relative to the other for putting the interiors of the two flasks into communica tion with one another, such displacement being under the guidance of an internally-threaded tubular casing carried by one of the flasks and into which is screwed a threaded neck of the other flask.

12. A package as set forth in claim 1 in which the flask containing the liquid carries a removable cover adapted to be detached from said spacing means and to replace the stopper means on the first flask onceopened.

Claims (12)

1. A package comprising two flasks of which at least one is of a flexible material and which are adapted to contain one a liquid and the other a solid product which is a selected member of the group consisting of substances dissolvable in and substances suspendible in said liquid at the time of use, stopper means on each flask and means for temporarily putting the interiors of the two flasks into communication with one another through at least one part of said stopper means, said at least one of the flasks being manually deformable to effect the passage of the liquid from its flask into that of the solid product and the return of the solution or of the suspension to the flask for the liquid, said flasks are kept together in alignment and in readiness for the putting of their contents into communication with each other by spacing means which can be torn away.
2. A package as set forth in claim 1, in which the stopper means on one of the flasks makes up at least partially a device for perforating the stopper means on the other flask.
3. A package as set forth in claim 2, in which said one of the flasks carries a dropper having a projecting end adapted for perforations of the stopper means of the other of the flasks.
4. A package as set forth in claim 3, in which the stopper means of said other of the flasks comprises a plug of elastomeric material held in the neck of the flask and having an axial bore stopped by means which can be overcome by said dropper projecting end.
5. A package as set forth in claim 4, in which said means which can be overcome is an ejectable ball.
6. A package as set forth in claim 4, in which said means which can be overcome is a perforable membrane.
7. A package as set forth in claim 4, in which said means which can be overcome consists of an ejectable ball and a perforable membrane.
8. A package as set forth in claim 7, in which the plug has thereabove a washer which is impervious to the liquid and is formed by a polyethylene disk coated on one of its faces with a film of aluminium.
9. A package as set forth in claim 4, in which said plug has thereabove a cover which includes a hemispherical central part located in alignment with said axial bore and which can be cut off at the time of use, said cover being retained on the plug by an encasing ring on the rim of the neck of the flask.
10. The package of claim 3 further including removable means for preventing the projecting end of said dropper from perforating the stopper of the other flask.
11. A package as set forth in claim 1, wherein one flask is adapted to be displaced relative to the other for putting the interiors of the two flasks into communication with one another, such displacement being under the guidance of an internally-threaded tubular casing carried by one of the flasks and into which is screwed a threaded neck of the other flask.
12. A package as set forth in claim 1 in which the flask containing the liquid carries a removable cover adapted to be detached from said spacing means and to replace the stopper means on the first flask once opened.
US3917063A 1972-06-13 1973-06-06 Packages enabling the extemporaneous preparation of suspensions or sterile solutions Expired - Lifetime US3917063A (en)

Priority Applications (1)

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FR7221179A FR2188565A5 (en) 1972-06-13 1972-06-13

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BE (1) BE800782A (en)
DE (1) DE2329704A1 (en)
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LU (1) LU67780A1 (en)

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US4573506A (en) * 1983-09-26 1986-03-04 Laboratories Merck Sharp & Dohme - Chibret Two-bottle assembly for preparing and dispensing a solution
US4591049A (en) * 1984-01-16 1986-05-27 Kidde, Inc. Hermetically sealed two-component mixing system
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US4858759A (en) * 1985-12-21 1989-08-22 Hilti Aktiengesellschaft Container arrangement for cartridge dispensing two-component mass
US4936446A (en) * 1988-03-02 1990-06-26 Laboratoires Merck, Sharp & Dohme-Chibret Packaging and dispensing system for packaging two ingredients separately and mixing them extemporaneously at the time of first use, and method of assembling same
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US7425209B2 (en) 1998-09-15 2008-09-16 Baxter International Inc. Sliding reconstitution device for a diluent container
US7641851B2 (en) 2003-12-23 2010-01-05 Baxter International Inc. Method and apparatus for validation of sterilization process
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EP0246835A3 (en) * 1986-05-21 1988-01-07 Johnsen & Jorgensen Jaypak Limited Improvements in and relating to systems and apparatus for mixing products
US4986322A (en) * 1987-03-24 1991-01-22 Societe Semco System of packaging for ready to use preparations
US4936446A (en) * 1988-03-02 1990-06-26 Laboratoires Merck, Sharp & Dohme-Chibret Packaging and dispensing system for packaging two ingredients separately and mixing them extemporaneously at the time of first use, and method of assembling same
US5207320A (en) * 1989-05-24 1993-05-04 Allen Nicholas J Compartmented mixing device with bead
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US5209565A (en) * 1991-12-20 1993-05-11 L'oreal Assembly adapted for the mixing of two different products stored separately
US5380315A (en) * 1992-02-04 1995-01-10 Material Engineering Technology Laboratory Incorporated Mixing apparatus
US5409141A (en) * 1992-03-13 1995-04-25 Nissho Corporation Two component mixing and delivery system
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US5893484A (en) * 1995-07-14 1999-04-13 Ing. Erich Pfeiffer Gmbh Discharge device for fluid media, particularly for single-stroke only discharge
US6164501A (en) * 1996-02-08 2000-12-26 Tebro Device for dispensing a fluid contained in a hermetically closed container
US6237649B1 (en) * 1997-08-27 2001-05-29 Pentapharm Ag Dual vial connecting system for lyophilized products
US6610040B1 (en) 1997-12-04 2003-08-26 Baxter International Inc. Sliding reconstitution device with seal
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US6852103B2 (en) 1997-12-04 2005-02-08 Baxter International Inc. Sliding reconstitution device with seal
EP0945364A3 (en) * 1998-03-23 2000-03-01 Wella Aktiengesellschaft Container for a two-component product
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US6582415B1 (en) 1998-09-15 2003-06-24 Thomas A. Fowles Sliding reconstitution device for a diluent container
US6022339A (en) * 1998-09-15 2000-02-08 Baxter International Inc. Sliding reconstitution device for a diluent container
US7358505B2 (en) 1998-09-15 2008-04-15 Baxter International Inc. Apparatus for fabricating a reconstitution assembly
US6875203B1 (en) 1998-09-15 2005-04-05 Thomas A. Fowles Vial connecting device for a sliding reconstitution device for a diluent container
US7425209B2 (en) 1998-09-15 2008-09-16 Baxter International Inc. Sliding reconstitution device for a diluent container
US6890328B2 (en) 1998-09-15 2005-05-10 Baxter International Inc. Sliding reconstitution device for a diluent container
US8226627B2 (en) 1998-09-15 2012-07-24 Baxter International Inc. Reconstitution assembly, locking device and method for a diluent container
US7074216B2 (en) 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
US20040050885A1 (en) * 2000-12-08 2004-03-18 Giuseppe Stradella Fluid or powdery product dispensing device
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US20050088496A1 (en) * 2003-10-22 2005-04-28 Lui Pui K. Ink refilling cap
US7641851B2 (en) 2003-12-23 2010-01-05 Baxter International Inc. Method and apparatus for validation of sterilization process
US8022375B2 (en) 2003-12-23 2011-09-20 Baxter International Inc. Method and apparatus for validation of sterilization
US20050238408A1 (en) * 2004-01-20 2005-10-27 L'oreal Kit comprising two receptacles and an applicator
US7534062B2 (en) * 2004-01-20 2009-05-19 L'oreal Kit comprising two receptacles and an applicator
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US20130079756A1 (en) * 2011-09-23 2013-03-28 Adapta Medical, Inc. Catheter Reservoir Seal
US8801698B2 (en) * 2011-09-23 2014-08-12 Adapta Medica, Inc. Catheter reservoir seal
US20140358127A1 (en) * 2011-09-23 2014-12-04 Adapta Medical, Inc. Catheter Reservoir Seal
CN105857890A (en) * 2016-06-06 2016-08-17 洛阳海惠新材料股份有限公司 Packaging container of ethylene glycol antimony
CN105857890B (en) * 2016-06-06 2018-03-23 洛阳海惠新材料股份有限公司 One of ethylene glycol antimony packaging container

Also Published As

Publication number Publication date Type
FR2188565A5 (en) 1974-01-18 application
FR2612892A2 (en) 1988-09-30 application
FR2612892B2 (en) 1989-09-08 grant
LU67780A1 (en) 1974-07-10 application
BE800782A1 (en) grant
BE800782A (en) 1973-12-12 grant
DE2329704A1 (en) 1973-12-20 application

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