US3906932A - Needle point for stopper penetration and method of making it - Google Patents

Needle point for stopper penetration and method of making it Download PDF

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Publication number
US3906932A
US3906932A US44634674A US3906932A US 3906932 A US3906932 A US 3906932A US 44634674 A US44634674 A US 44634674A US 3906932 A US3906932 A US 3906932A
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Prior art keywords
needle
stopper
tips
another
end
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Waldemar A Ayres
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Becton Dickinson and Co
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Becton Dickinson and Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B21MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21GMAKING NEEDLES, PINS OR NAILS OF METAL
    • B21G1/00Making needles used for performing operations
    • B21G1/08Making needles used for performing operations of hollow needles or needles with hollow end, e.g. hypodermic needles, larding-needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/19Constructional features of carpules, syringes or blisters
    • A61M2205/192Avoiding coring, e.g. preventing formation of particles during puncture
    • A61M2205/195Avoiding coring, e.g. preventing formation of particles during puncture by the needle tip shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286Needle tip design, e.g. for improved penetration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291Shafts with additional lateral openings

Abstract

A needle point particularly suited for insertion through a container stopper is not deflected to one side during penetration of the stopper. The needle is also non-coring during its passage through the stopper. The needle point has two diagonal faces instead of the usual one. The two faces are on opposite sides of the cannula body so that vector forces applied to each face during passage through a stopper are equal and opposite (therefore self-cancelling). During passage through the stopper, the needle continues in a straight path along the axial line of the needle without sideways deflection. The method of fabricating the new needle comprises (1) making a first diagonal grind on the cannula, (2) rotating the cannula 180* and making a second diagonal grind, and (3) bending the cannula wall tips to bring them together at the axial line.

Description

United States Patent [191 Ayres [451 Sept. 23, 1975 NEEDLE POINT FOR STOPPER PENETRATION AND METHOD OF MAKING IT [75] Inventor: Waldemar A. Ayres, Rutherford,

[73] Assignee: Becton, Dickinson and Company,

East Rutherford, NJ.

22 Filed: Feb. 27, 1974 21 Appl. No: 446,346

[52] US. Cl. 128/2 F; 128/221; 128/272; 222/80; 72/369 [51] Int. Cl.*.... A61B 5/14; A678 7/24; B21D 9/00 [58] Field of Search 128/221, 339,218 N, 215, 128/218 NV, 218 D, 218 R, 218 DA, 218 M,

[56] References Cited UNITED STATES PATENTS 1,331,271 2/1920 MacGregor [28/221 3,181,336 5/1965 Schofield 128/221 X 3,327,710 6/1967 Freeberg et al.... 128/218 M 3,540,112 11/1970 Knox 128/221 X 3,594,296 7/1971 Derwall 128/221 X FOREIGN PATENTS OR APPLICATIONS 591,985 2/1960 Canada 128/221 Primary Examiner-Richard A. Gaudet Assistant ExaminerJ. C. McGowan Attorney, Agent, or Firm-Kane, Dalsimer. Kane, Sullivan and Kurucz [57] ABSTRACT A needle point particularly suited for insertion through a container stopper is not deflected to one side during penetration of the stopper. The needle is also non-coring during its passage through the stopper. The needle point has two diagonal faces instead of the usual one. The two faces are on opposite sides of the cannula body so that vector forces applied to each face during passage through a stopper are equal and opposite (therefore self-cancelling). During passage through the stopper, the needle continues in a straight path along the axial line of the needle without side ways deflection.

The method of fabricating the new needle comprises (1) making a first diagonal grind on the cannula, (2) rotating the cannula 180 and making a second diagonal grind, and (3) bending the cannula wall tips to bring them together at the axial line.

5 Claims, 8 Drawing Figures US Patent Sept. 23,1975 Sheet 1 of 2 3,906,932

lggl

US Patent Sept. 23,1975 Sheet 2 of2 3,06,932

NEEDLE POINT FOR STOPPER PENETRATION AND METHOD OF MAKING IT BACKGROUND OF THE INVENTION With the double ended needle used in the Vacutainer tube supplied commercially by Becton, Dickinson and Company of East Rutherford, N..l., the usual diagonal bevel of the point which penetrates the rubber stopper frequently causes this needle to be deflected considera bly off-center. This occasionally results in the needle point failing to emerge into the central well of the stopper (instead, remaining embedded in the sidewall), whereupon no blood can enter the Vacutainer tube and the device is a failure. The diagonal face of the needle point is clearly the factor which causes this deflection off-center, in most cases.

This difficulty is also a design limitation in devising various kinds of stoppers, particularly for new and special purposes. To avoid the hazard of the above type of malfunction, present stopper design practice requires that a large central well, on the lower side of the stopper, be maintained, and that the roof of this well be horizontal, or substantially so, across its diameter. For various special types of Vacutainer tubes, the diameter of the central well could advantageously be made much smaller and, in some cases, provide a curved or conical roof. In these cases, if the needle were deflected substantially off-center during insertion, the needle point would be likely to remain embedded in the stopper sidewall, or within the increased thickness of the curved or conical roof, without emerging, thus preventing blood from flowing and causing failure of the device.

SUMMARY OF THE INVENTION It is a principal object of the present invention to provide a new needle point which eliminates the forces tending to produce needle deflection during stopper penetration thereby rendering it further feasible to permit increased design flexibility for producing new stoppers.

A further object is to provide a needle point for stopper penetration which is bilaterally symmetrical so that any deflection forces, due to diagonal surfaces, are made equal and opposite so that they are selfcancelling, about the long axis of the needle; the needle point does not core; the needle point is simple, inexpensive and practical to manufacture in large quantities; and the needle point does not produce excessive hemolysis.

Other objects and advantages will become apparent from the following detailed description which is to be taken in conjunction with the accompanying drawings.

DESCRIPTION OF THE DRAWINGS In the drawings FIG. 1 is a side elevational view ofa stopper penetrating needle at an intermediate stage of its manufacture with the opposed tips being spaced apart;

FIG. 2 is the final needle with the tips bent towards one another in substantially abutting relationship;

FIG. 3 is the bottom plan view of the partially formed needle point of FIG. ll;

FIG. 4 is the bottom plan view of the finished needle of FIG. 2;

FIG. 5 is an elevational view with certain parts broken away and removed and sectioned for clarity show ing the needle of the present invention penetrating a stopper of an evacuated tube;

FIG. 6 is a side elevational view of a quantity of needle blanks lying side by side between rigid plates in the course of manufacture, and one plate is moved laterally relative to the other to rotate the needles a predetermined amount;

FIG. 7 is a side elevational view illustrative of a grinding operation contemplated by the present invention; and

FIG. 8 shows the partially formed needle blank being supported between plates with bevel-faced squeeze bars moved towards one another to bend the tips in substantial abutting relationship to form the finished needle of FIG. 2.

DETAILED DESCRIPTION Referring initially to FIGS. I and 3, a partially formed needle blank for penetrating a stopper is initially provided with a pair of opposed bevel-faces l2 and 14 to form a pair of diametrically opposed pointed tips 16 and 18. The force vectors produced by these faces during stopper penetration are equal and opposite and hence self-cancelling with no lateral deflection being produced and an axial vector remaining. However in actual practice the needle blank 10 as shown with beveled faces 12 and 14 would cut a core out of the rubber stopper and consequently this would be objectionable.

It has been found that finished needles 40 having tips 16 and I8 bent inwardly into abutting relationship thereby defining beveled faces 12a and 12b and inwardly bent substantially abutting tips 16a and 18:! enter a stopper without any sideways deflection and without coring.

This penetration into stopper 20 of an evacuated tube 22 is depicted in FIG 5.

Turning now to FIGS. 6 to 8, :an exemplary manufacturing method is illustrated for producing the needles 10a illustrated in FIGS, 2, 4 and 5. Initially needle blanks 10 are disposed and pressed between rigid plates 24 and 26. The needles 10 lie side by side and upon lat' eral movement of one of the plates relative to the other, these needle blanks are adapted to rotate about their respective axes. In this fashion a grinding wheel may be actuated to pass across the tips of the group of needle blanks for purposes of grinding different faces at prede termined angles. Thus in FIG. '7 the needle blanks 10a are provided with bevel-face 12 by the grinding wheel 28. This wheel 28 will then grind bevel-face l4 following shifting of one of the plates 24 and 26 to rotate the needles 180. Alternatively the needles 10 may be held stationary and a second grinding wheel may be passed along the underside to grind the bevel-faces 14. Following the grinding of the two beveled faces 16 and 17, the rigid plates 24 and 26 could be moved relative to each other so that each of the needle blanks would be rotated about their respective axes to the position shown in FIG. 8. Then bevel-faced squeeze bars 30 and 32 would be reciprocated towards one another to bend the tips 16a and 18a as shown to produce the finished needle 10a. Thereafter the processes of deburring, cleaning, etc., could be followed in accordance with well known techniques in the needle art.

Although several somewhat preferred emobodiments of the invention have been disclosed and described in detail herein, it should be understood that this invention is in no sense limited thereby and its scope is to be determined by that of the appended claims What is claimed is:

l. A stopper penetrating needle including a tubular portion having a stopper penetrating end, the end having two beveled faces 180 apart from each other and in converging relationship defining a pair of opposed tips, the tips being bent toward one another whereby the points of each tip are substantially adjacent one another but not united to provide a stopper penetrating pointed end being substantially free of lateral deflection and coring when inserted into the stopper.

2. The invention in accordance with claim 1 wherein the points of the tips are bent into contact with one another.

3. A method of producing a stopper penetrating needle with an end free of lateral deflection and coring when inserted into the stopper including the steps of:

a. providing a plurality of needle blanks essentially in tubular form each having a stopper penetrating end;

b. grinding opposed convergent beveled faces in the tubular needle blanks at the stopper penetrating ends and thereby defining a pair of opposed pointed tips at this end; and

e. bending the tips towards one another into substantial engagement but not united with one another to form the finished stopper penetrating end.

4. The invention in accordance with claim 3 wherein the needle blanks are pressed between two rigid plates relatively movable in a lateral direction with respect to one another and in forming the beveled faces the needle blanks are rotated about their respective axes 180 to permit a grinding wheel to pass twice over the needle blank ends to form the two beveled faces.

5. The invention in accordance with claim 4 wherein the pressed needle blanks are moved about their respective axes through the relative lateral reciprocation of the plates to thereby expose the needle blank ends with beveled faces to a pair of bevel-faced squeeze bars for bending the pointed tips.

Claims (5)

1. A stopper penetrating needle including a tubular portion having a stopper penetrating end, the end having two beveled faces 180* apart from each other and in converging relationship defining a pair of opposed tips, the tips being bent toward one another whereby the points of each tip are substantially adjacent one another but not united to provide a stopper penetrating pointed end being substantially free of lateral deflection and coring when inserted into the stopper.
2. The invention in accordance with claim 1 wherein the points of the tips are bent into contact with one another.
3. A method of producing a stopper penetrating needle with an end free of lateral deflection and coring when inserted into the stopper, including the steps of: a. providing a plurality of needle blanks essentially in tubular form each having a stopper penetrating end; b. grinding opposed convergent beveled faces in the tubular needle blanks at the stopper penetrating ends and thereby defining a pair of opposed pointed tips at this end; and c. bending the tips towards one another into substantial engagement but not united with one another to form the finished stopper penetrating end.
4. The invention in accordance with claim 3 wherein the needle blanks are pressed between two rigid plates relatively movable in a lateral direction with respect to one another and in forming the beveled faces the needle blanks are rotated about their respective axes 180* to permit a grinding wheel to pass twice over the needle blank ends to form the two beveled faces.
5. The invention in accordance with claim 4 wherein the pressed needle blanks are moved 90* about their respective axes through the relative lateral reciprocation of the plates to thereby expose the needle blank ends with beveled faces to a pair of bevel-faced squeeze bars for bending the pointed tips.
US44634674 1974-02-27 1974-02-27 Needle point for stopper penetration and method of making it Expired - Lifetime US3906932A (en)

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Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468224A (en) * 1982-01-28 1984-08-28 Advanced Cardiovascular Systems, Inc. System and method for catheter placement in blood vessels of a human patient
US4585446A (en) * 1984-03-16 1986-04-29 Joseph Kempf Dialysis needle
US4753641A (en) * 1987-09-10 1988-06-28 Vaslow Dale F Emergency medical needle
US4826492A (en) * 1986-01-10 1989-05-02 Hospal Ltd. Medical probe
US5207658A (en) * 1991-11-14 1993-05-04 Rosen Howard J Prick resistant medical needle for intravenous injections
US5254106A (en) * 1992-04-17 1993-10-19 Feaster Fred T Hydrodissection needle
US5478328A (en) * 1992-05-22 1995-12-26 Silverman; David G. Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method
US5520193A (en) * 1993-02-22 1996-05-28 Issei Suzuki Blood collecting needle with vein indicator
US5713874A (en) * 1995-08-01 1998-02-03 Kind-R-Ject Company, Llc Camouflaged injection needle
US20020091359A1 (en) * 2000-12-12 2002-07-11 Luca Caleffi Site for access to the inside of a channel, and corresponding cannula
US6702790B1 (en) * 2002-10-31 2004-03-09 Chauncey F. Ross Hypodermic needle
US6702791B1 (en) 1999-02-04 2004-03-09 Integ, Inc. Needle for body fluid tester
US20040062407A1 (en) * 1999-06-08 2004-04-01 Harman Audio Electronic Systems Gmbh Loudspeaker with a front-mounted sealing element and method of manufacturing the same
WO2004035118A1 (en) * 2002-10-17 2004-04-29 Hans Haindl Method for producing a cannula used specially for a spinal anaesthesia
US6802199B2 (en) 1999-02-04 2004-10-12 Integ, Inc. Needle for body fluid tester
EP1466645A2 (en) * 2003-04-08 2004-10-13 Nipro Corporation Connector set for medical use and indwelling catheter set using such connector set
US20040260203A1 (en) * 2001-12-12 2004-12-23 Arkray Inc. Method and implement for opening hole in soft material
US20050171567A1 (en) * 2004-01-29 2005-08-04 Dehart Damon H. Lancet and method of manufacturing the same
US20050215977A1 (en) * 2004-03-25 2005-09-29 Uschold John E Needles and methods of using same
US20060027009A1 (en) * 2004-08-05 2006-02-09 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US20060027010A1 (en) * 2004-08-05 2006-02-09 Becton, Dickinson And Company Method of producing tapered or pointed cannula
WO2007122254A1 (en) * 2006-04-26 2007-11-01 Novo Nordisk A/S A cannula for an injection device, the cannula having a tapered end, and a method for manufacturing the same
US20080228104A1 (en) * 2004-03-11 2008-09-18 Uber Arthur E Energy Assisted Medical Devices, Systems and Methods
WO2009060047A1 (en) * 2007-11-06 2009-05-14 Aseptic Technologies S.A. Pyramid shaped needle point.
US20090126636A1 (en) * 2007-11-21 2009-05-21 Correa Rafael S Combined punch and needle for automated egg injection machines
US20090326485A1 (en) * 2008-06-30 2009-12-31 Carlyon James L Blunt tip vial access cannula and method for manufacture
US20130046224A1 (en) * 2011-08-11 2013-02-21 Adrian Ravenscroft Method and apparatus for the dialysis of blood
JP2013103077A (en) * 2011-11-16 2013-05-30 Nipro Corp Vaccination needle
JP2014066706A (en) * 2012-09-24 2014-04-17 Siemens Healthcare Diagnostics Products Gmbh Hollow needle for sample pipettor
CN105078753A (en) * 2015-09-10 2015-11-25 肖刚 Hydro-acupuncture rapid dispensing apparatus
WO2016172278A1 (en) * 2015-04-22 2016-10-27 Guiles Marvin A Method and system for harvesting biological tissue

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US1331271A (en) * 1918-04-02 1920-02-17 Macgregor Instr Company Syringe
US3181336A (en) * 1961-11-15 1965-05-04 Schofield Hubert Percival Method of producing the pointed end of a hypodermic needle
US3327710A (en) * 1963-11-15 1967-06-27 Santo John De Combination hypodermic syringe and mixing container
US3540112A (en) * 1967-01-18 1970-11-17 Knox Lab Inc Method for manufacturing a hypodermic needle
US3594296A (en) * 1966-11-15 1971-07-20 Schumag Schumacher Metallwerke Apparatus for grinding the tips of injection needles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1331271A (en) * 1918-04-02 1920-02-17 Macgregor Instr Company Syringe
US3181336A (en) * 1961-11-15 1965-05-04 Schofield Hubert Percival Method of producing the pointed end of a hypodermic needle
US3327710A (en) * 1963-11-15 1967-06-27 Santo John De Combination hypodermic syringe and mixing container
US3594296A (en) * 1966-11-15 1971-07-20 Schumag Schumacher Metallwerke Apparatus for grinding the tips of injection needles
US3540112A (en) * 1967-01-18 1970-11-17 Knox Lab Inc Method for manufacturing a hypodermic needle

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468224A (en) * 1982-01-28 1984-08-28 Advanced Cardiovascular Systems, Inc. System and method for catheter placement in blood vessels of a human patient
US4585446A (en) * 1984-03-16 1986-04-29 Joseph Kempf Dialysis needle
US4826492A (en) * 1986-01-10 1989-05-02 Hospal Ltd. Medical probe
US4753641A (en) * 1987-09-10 1988-06-28 Vaslow Dale F Emergency medical needle
US5207658A (en) * 1991-11-14 1993-05-04 Rosen Howard J Prick resistant medical needle for intravenous injections
US5254106A (en) * 1992-04-17 1993-10-19 Feaster Fred T Hydrodissection needle
US5478328A (en) * 1992-05-22 1995-12-26 Silverman; David G. Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method
US5520193A (en) * 1993-02-22 1996-05-28 Issei Suzuki Blood collecting needle with vein indicator
US5713874A (en) * 1995-08-01 1998-02-03 Kind-R-Ject Company, Llc Camouflaged injection needle
US20040236249A1 (en) * 1999-02-04 2004-11-25 Hilgers Michael Edward Needle for body fluid tester
US6802199B2 (en) 1999-02-04 2004-10-12 Integ, Inc. Needle for body fluid tester
US6702791B1 (en) 1999-02-04 2004-03-09 Integ, Inc. Needle for body fluid tester
US20040062407A1 (en) * 1999-06-08 2004-04-01 Harman Audio Electronic Systems Gmbh Loudspeaker with a front-mounted sealing element and method of manufacturing the same
US20020091359A1 (en) * 2000-12-12 2002-07-11 Luca Caleffi Site for access to the inside of a channel, and corresponding cannula
US6936031B2 (en) 2000-12-12 2005-08-30 Gambro Dasco S.P.A. Site for access to the inside of a channel, and corresponding cannula
US7776023B2 (en) 2001-12-12 2010-08-17 Arkray, Inc. Method and implement for opening hole in soft material
US20090171246A1 (en) * 2001-12-12 2009-07-02 Arkray Inc. Method and Implement for Opening Hole in Soft Material
US20040260203A1 (en) * 2001-12-12 2004-12-23 Arkray Inc. Method and implement for opening hole in soft material
US7458142B2 (en) * 2002-10-17 2008-12-02 Hans Haindl Method for producing a cannula used specially for a spinal anaesthesia
WO2004035118A1 (en) * 2002-10-17 2004-04-29 Hans Haindl Method for producing a cannula used specially for a spinal anaesthesia
US20050275136A1 (en) * 2002-10-17 2005-12-15 Hans Haindl Method for producing a cannula used specially for a spinal anaesthesia
US20040087915A1 (en) * 2002-10-31 2004-05-06 Ross Chauncey F. Hypodermic needle
US6702790B1 (en) * 2002-10-31 2004-03-09 Chauncey F. Ross Hypodermic needle
US6945964B2 (en) * 2002-10-31 2005-09-20 Dianne L. Hilderbrand Hypodermic needle
EP1466645A3 (en) * 2003-04-08 2005-04-27 Nipro Corporation Connector set for medical use and indwelling catheter set using such connector set
US20040204690A1 (en) * 2003-04-08 2004-10-14 Kenji Yashiro Connector set for medical use and indwelling catheter set using such connector set
EP1466645A2 (en) * 2003-04-08 2004-10-13 Nipro Corporation Connector set for medical use and indwelling catheter set using such connector set
WO2005072610A3 (en) * 2004-01-29 2005-11-03 Abbott Lab Lancet and method of manufacturing the same
WO2005072610A2 (en) 2004-01-29 2005-08-11 Abbott Laboratories Lancet and method of manufacturing the same
US20050171567A1 (en) * 2004-01-29 2005-08-04 Dehart Damon H. Lancet and method of manufacturing the same
US20080228104A1 (en) * 2004-03-11 2008-09-18 Uber Arthur E Energy Assisted Medical Devices, Systems and Methods
US20050215977A1 (en) * 2004-03-25 2005-09-29 Uschold John E Needles and methods of using same
US7645268B2 (en) * 2004-03-25 2010-01-12 Boston Scientific Scimed, Inc. Needles and methods of using same
WO2005102426A1 (en) * 2004-03-25 2005-11-03 Boston Scientific Scimed, Inc. Needles
US7076987B2 (en) 2004-08-05 2006-07-18 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US7086266B2 (en) 2004-08-05 2006-08-08 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US20060027010A1 (en) * 2004-08-05 2006-02-09 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US20060027009A1 (en) * 2004-08-05 2006-02-09 Becton, Dickinson And Company Method of producing tapered or pointed cannula
US20090163877A1 (en) * 2006-04-26 2009-06-25 Novo Nordosk A/S Cannula For An Injection Device, The Cannula Having A Tapered End, And A Method For Manufacturing the Same
WO2007122254A1 (en) * 2006-04-26 2007-11-01 Novo Nordisk A/S A cannula for an injection device, the cannula having a tapered end, and a method for manufacturing the same
WO2009060047A1 (en) * 2007-11-06 2009-05-14 Aseptic Technologies S.A. Pyramid shaped needle point.
US8720501B2 (en) 2007-11-06 2014-05-13 Aseptic Technologies S.A. Pyramid shaped needle point
US20100294796A1 (en) * 2007-11-06 2010-11-25 Jacques Thilly Pyramid shaped needle point
US20090126636A1 (en) * 2007-11-21 2009-05-21 Correa Rafael S Combined punch and needle for automated egg injection machines
US20090326485A1 (en) * 2008-06-30 2009-12-31 Carlyon James L Blunt tip vial access cannula and method for manufacture
US8382722B2 (en) * 2008-06-30 2013-02-26 Covidien Lp Blunt tip vial access cannula and method for manufacture
US20140053953A1 (en) * 2008-06-30 2014-02-27 Covidien Lp Blunt tip vial access cannula and method for manufacture
US9713573B2 (en) * 2008-06-30 2017-07-25 Covidien Lp Blunt tip vial access cannula and method for manufacture
US9044573B2 (en) * 2011-08-11 2015-06-02 Phase One Medical, Llc Method and apparatus for the dialysis of blood
US20130046224A1 (en) * 2011-08-11 2013-02-21 Adrian Ravenscroft Method and apparatus for the dialysis of blood
JP2013103077A (en) * 2011-11-16 2013-05-30 Nipro Corp Vaccination needle
US10040060B2 (en) 2012-09-24 2018-08-07 Siemens Healthcare Diagnostics Products Gmbh Hollow needle for a sample pipettor
JP2014066706A (en) * 2012-09-24 2014-04-17 Siemens Healthcare Diagnostics Products Gmbh Hollow needle for sample pipettor
WO2016172278A1 (en) * 2015-04-22 2016-10-27 Guiles Marvin A Method and system for harvesting biological tissue
CN105078753A (en) * 2015-09-10 2015-11-25 肖刚 Hydro-acupuncture rapid dispensing apparatus

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