US3903886A - Glass lined injector - Google Patents

Glass lined injector Download PDF

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Publication number
US3903886A
US3903886A US37867273A US3903886A US 3903886 A US3903886 A US 3903886A US 37867273 A US37867273 A US 37867273A US 3903886 A US3903886 A US 3903886A
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Grant
Patent type
Prior art keywords
syringe
end
injector
body
hub
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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Inventor
Kazuo Omotani
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Kazuo Omotani
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3137Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps

Abstract

A cylindrical injection syringe is made of synthetic resin and has the inner sides tightly lined with glass. The outlet at the needle end is sealed by a thin film of the same resin as the syringe is made from and is molded integrally with the syringe; and the interior of the syringe may be covered with an anticorrosive protective film.

Description

United States Patent 11 1 Omotani 1 Sept. 9, 1975 1 1 GLASS LINED INJECTOR [76] Inventor: Kazuo Om0tani,7-27-Higashi 2 Ch0me, Hiroshima Japan {22] Filed: July 12, 1973 [211 Appl. No: 378,672

[30] Foreign Application Priority Data July 12. 1972 Jupzui I v v I I I 47419154 Oct. 2 1972 Japan 47-113420 [52} U.S. Cl. 1. 128/218 DA; 128/272 [51] Int. Cl. A611" 5/28;A61.1 1/06 [58] Field of Searchm. 128/218 DA, 218 D 218 M 128/218 P. 218 R. DIG 28 215, 234 220,

[56] References Cited UNITED STATES PATENTS 2.5(11233 7/1951 Ryan ct a1 .1 128/218 D 2568.029 9/1951 Scumur.... 1 128/272 Z V/KJM 12/1951 Bluckmun I I I I I I I 128/218 P 2.721))(811 111/1955 Whitaker ct lll. 1. 128/218 D Primary E.mminerRichard A. Gaudet Ass/slam Exuminer.l. C. McGowan A/mrney Agent, or FirmWi1Iiam Anthony Drucker (57] ABSTRACT A cylindrical injection syringe is made of synthetic resin and has the inner sides tightly lined with glass. The outlet at the needle end is sealed by a thin film of the same resin as the syringe is made from and is molded integrally with the syringe; and the interior of the syringe may be covered with an anti corrosive protective film.

5 Claims, 6 Drawing Figures CLASS LINED INJECTOR This invention relates to improvements in injectors made of synthetic resin. More particularly, it concerns an injector syringe with the inner periphery lined with a glass pipe. The inner end surface of the glass pipe is covered with such material as anti corrosive synthetic resin or synthetic rubber, so that the injector syringe itself can serve as a sealed container for liquid chemical which can be directly administered by operating with a piston rod a plug piston fitted in the upper end of the syringe.

It is well known in the art that injectors made of synthetic resins have been recently developed and they are inexpensive so that they can be used as consumables, being discarded after use, thus providing very hygienic effect. However, the liquid chemical used for administration is filled in an ampoule, and it must be withdrawn into the injector syringe by cutting the ampoule at the time of use. Thus, the operation is troublesome, and also minute glass particles are likely to be mingled into the liquid chemical at the time of cutting the ampoule. Further, the ampoule is prone to damage during transport or due to other causes.

In order to solve these problems, a cylindrical synthetic resin cartridge filled with liquid chemical and loaded in the injector syringe has been developed. However, this cartridge is naturally separate from the injector syringe, thus requiring separate manufacturing steps. Also, time and labor are required when loading the cartridge into the injector syringe. Further, depending upon the liquid chemical filled in the cartridge, the cartridge is prone to de-generation due to its contact with the synthetic resin. Furthermore, the injector syringe is prone to cracks or clefts when ambient temperature is low, although it has the merits of cheapness and handiness.

An object of the invention is to provide an injector having an injector syringe, which is made of a synthetic resin and has reinforced mechanical strength with its inner periphery lined with a glass pipe without using any adhesive.

Another object of the invention is to provide an injector, with which the liquid chemical preserved within the injector syringe is free from contact with the synthetic resin constituting the inner wall of the syringe and the chemical alteration of the drug is perfectly prevented.

The invention will now be described in conjunction with some embodiments thereof with reference to the accompanying drawing, in which:

FIG. 1 illustrates the manner of fitting a glass pipe into the injector syringe;

FIG. 2 is a longitudinal cross-section of an injector according to the invention;

FIG. 3 is a longitudinal cross-section showing another embodiment of the invention;

FIG. 4 is a front view showing a piston rod;

FIG. 5 is a longitudinal sectional view showing another cxample of the piston rod, and

FIG. 6 is a sectional view showing an injector needle used for the injector according to the invention.

In accordance with the invention, a glass pipe Sis fitted into and made integral with an injector syringe I made of a synthetic resin. as shown in FIG. I, thus providing a glass lining on the inner periphery of the injector syringe l as shown in FIG. 2. The syringe I has an injector needle mount 2 provided at its forward end.

The passage 3 in the mount 2 is closed with a thin nodal film 4. The film 4 preferably has a profile upwardly curved as shown in FIG. 2. A liquid chemical 13 is poured into the injector syringe l lined with the glass pipe 5 from the upper end opening thereof, and then a plug stopper or piston 6 made of anti-corrosive rubber or similar material is fitted in the open end. The plug piston 6 is formed with a threaded bore 7 open at its top.

FIG. 3 shows another injector according to the invention. In this injector, the inner surface of the forward end of an injector syringe l is not protected by the glass pipe 5. Said injector forward end and the curved thin nodal film 4 are covered by an integrated protection film 14 of a material such as an anti-corrosive synthetic resin or silicone rubber.

The injector as described above according to the invention is combined with a piston rod 9 as shown in FIG. 4 or piston rod 9a as shown in FIG. 5 and an injector needle 11 as shown in FIG. 6.

The piston rod 9 shown in FIG. 4 is provided at its forward end with a threaded projection 10, which is screwed into the connection bore 7 formed in the plug piston 6 fitted in the upper end of the injector syringe l. The piston 9a shown in FIG. 5 has a hollow inner space, in which the injector needle II is accommodated, and which is sealed with a cap 15. This piston rod is also provided at its end with a threaded projection 10a to be screwed into the plug piston 6.

The injector needle shown in FIG. 6 has a hub 12 made of a synthetic resin. The upper end 11a of the needle penetrates the hub 12 and projects therefrom.

In the drawing, numberal 8 designates a rib projecting into the open end of the syringe for preventing the accidental removal of the glass pipe 5.

The injector of the above construction according to the invention in situ constitutes a container, and the chemical 13 is sealed in it. To use this injector, the hub 12 of the injector needle I] is first fitted on the injector needle mount 2 projecting from the end of the injector syringe 1, whereby the upper end 11a of the needle penetrates the nodal film 4 closing the passage 3 and intrudes into the interior of the syringe l for communication with the liquid chemical. Then, the threaded projection 10 or 10a of the piston rod 9 or 90 of FIG. 3 or 4 is screwed into the connecting bore 7 of the plug piston 6. Then, by pushing the piston rod 9 or 90 in the axial direction, the plug piston 6 is caused to slide along the inner periphery of the glass pipe 5, thus forcing out the liquid chemical from the injector needle 11. At this time, if the nodal film penetrated by the upper end of the needle has an upwardly curved profile as shown in FIG. 4, the curved film 4 is downwardly pressed with the pressure exerted by the chemical, so that it is strongly and closely urged against the periphery of the upper needle end portion lla to thereby perfectly prevent the leakage of the liquid.

The injector according to the invention has various advantages. Firstly, since the injector syringe I itself serves as a container containing the liquid chemical sealed therein, the operation of withdrawing the liquid from an ampoule or the operation of loading a separate cartridge as in the prior art is not necessary. but it can be immediately used for administration by connecting the piston rod 9 or 9a to the plug piston 6. Secondly, since the injector syringe I is lined with the glass pipe 5 and protection film 14, the liquid chemical filled therein is not prone to alternation. Further, by virture of the double-wall structure the contraction and fissure of the synthetic resin in cold temperature can be perfectly prevented.

A method of manufacturing the syringe of the above construction will now be described. When lining the syringe 1 with the glass pipe 5, it is most important that the glass pipe 5 and synthetic resin body 1 of the syringe are integrally secured to each other. Also, increasing the production efficiency is important for reducing the cost of the injectors as the disposable.

In the aforementioned method, the glass pipe 5 has an outer diameter 0.1 to 0.2 millimeter smaller than the inner diameter of the syringe body 1 and is mechanically dropped from above the syringe body and fitted therein as shown in FIG. 1. The glass pipe 5 has a length suitable to the axial length of the syringe body 1. The syringe body 1 with the glass pipe 5 fitted therein is then transferred to a heating means, which is preferably an infrared radiation furnace or the like or may be an ordinary heating furnace. in the heating means, the syringe 1 is subjected to a heating treatment at a deformation threshold temperature. At this time, the molecules of the synthetic resin syringe body 1 are stabilized, and at the same time sterilization of the whole system is effected. With this treatment at the aforementioned deformation threshold temperature, the synthetic resin is subjected to the annealing contraction and perfectly secured to the glass pipe 5 for example by heat shrinking.

What is claimed is:

l. A double layer cylindrical injection syringe comprising: a continuous outer tubular body of synthetic resin free from openings along the length thereof and having at one end an integral needle securing hollow hub sealed fully across the entire inner end by a thin rupturable film; an injection needle on said hub; and at the other end of said body a radially projecting gripping flange and an opening sealed by axially displaccable plug means, the entire length of said body being integrally lined along the interior wall by a tightly fitted thin glass tube open at at least one end and positioned between said body and said plug means.

2. A syringe according to claim 1 including a piston rod and plug means which includes a socket for connection to said piston rod for driving the plug means along the glass tube towards the needle hub as a piston head to expel the contents of said tube through said hub.

3. A syringe according to claim 1 in which the rupturable film is made from the same synthetic resin as the tubular syringe body and an injectable liquid is sealed inside the glass tube by said film which is inflected radially to the interior of said tube and includes an interior protective coating extending fully across the inside of the hub end of said syringe.

4. A syringe according to claim 2 including means for storage of a needle within said piston rod.

5. A syringe according to claim 1 in which the resin and glass are tightly shrink fitted to each other.

Claims (5)

1. A double layer cylindrical injection syringe comprising: a continuous outer tubular body of synthetic resin free from openings along the length thereof and having at one end an integral needle securing hollow hub sealed fully across the entire inner end by a thin rupturable film; an injection needle on said hub; and at the other end of said body a radially projecting gripping flange and an opening sealed by axially displaceable plug means, the entire length of said body being integrally lined along the interior wall by a tightly fitted thin glass tube open at at least one end and positioned between said body and said plug means.
2. A syringe according to claim 1 including a piston rod and plug means which includes a socket for connection to said piston rod for driving the plug means along the glass tube towards the needle hub as a piston head to expel the contents of said tube through said hub.
3. A syringe according to claim 1 in which the rupturable film is made from the same synthetic resin as the tubular syringe body and an injectable liquid is sealed inside the glass tube by said film which is inflected radially to the interior of said tube and includes an interior protective coating extending fully across the inside of the hub end of said syringe.
4. A syringe according to claim 2 including means for storage of a needle within said piston rod.
5. A syringe according to claim 1 in which the resin and glass are tightly shrink fitted to each other.
US3903886A 1972-07-12 1973-07-12 Glass lined injector Expired - Lifetime US3903886A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP6915472A JPS5664B2 (en) 1972-07-12 1972-07-12
JP11342072 1972-10-02

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DE (1) DE2335095A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994044A (en) * 1988-10-18 1991-02-19 Carmelo Lo Duca Protected needle syringe
US5137511A (en) * 1987-07-08 1992-08-11 Duoject Medical Systems Inc. Syringe
US5364369A (en) * 1987-07-08 1994-11-15 Reynolds David L Syringe
US6016800A (en) * 1997-10-24 2000-01-25 Century; Theodore J. Intrapulmonary aerosolizer
EP1488758A1 (en) * 2003-06-18 2004-12-22 3M Espe Ag Dispensing cartridge
US20130174518A1 (en) * 2010-09-24 2013-07-11 Terumo Kabushiki Kaisha Method of assembling medicament injection device

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2561233A (en) * 1949-03-19 1951-07-17 Abbott Lab Hypodermic syringe
US2568029A (en) * 1950-02-09 1951-09-18 George H Seemar Unitary container for hypodermic injection ingredients
US2578394A (en) * 1947-12-04 1951-12-11 Premo Pharmaceutical Lab Inc Hypodermic syringe
US2720880A (en) * 1954-07-09 1955-10-18 Bishop & Co Platinum Works J Disposable cartridge syringe
US2768623A (en) * 1954-12-29 1956-10-30 John F Marchand Container for liquids, and more particularly to a container which incorporates therein the function of a syringe
US2813528A (en) * 1956-02-13 1957-11-19 Omega Prec Medical Instr Co In Hypodermic syringe
US3303846A (en) * 1963-10-08 1967-02-14 Functional Container Corp Mixing syringe having separate compartments for incompatible medicaments
US3464414A (en) * 1963-07-31 1969-09-02 Upjohn Co Mixing vial construction

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2578394A (en) * 1947-12-04 1951-12-11 Premo Pharmaceutical Lab Inc Hypodermic syringe
US2561233A (en) * 1949-03-19 1951-07-17 Abbott Lab Hypodermic syringe
US2568029A (en) * 1950-02-09 1951-09-18 George H Seemar Unitary container for hypodermic injection ingredients
US2720880A (en) * 1954-07-09 1955-10-18 Bishop & Co Platinum Works J Disposable cartridge syringe
US2768623A (en) * 1954-12-29 1956-10-30 John F Marchand Container for liquids, and more particularly to a container which incorporates therein the function of a syringe
US2813528A (en) * 1956-02-13 1957-11-19 Omega Prec Medical Instr Co In Hypodermic syringe
US3464414A (en) * 1963-07-31 1969-09-02 Upjohn Co Mixing vial construction
US3303846A (en) * 1963-10-08 1967-02-14 Functional Container Corp Mixing syringe having separate compartments for incompatible medicaments

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137511A (en) * 1987-07-08 1992-08-11 Duoject Medical Systems Inc. Syringe
US5364369A (en) * 1987-07-08 1994-11-15 Reynolds David L Syringe
US4994044A (en) * 1988-10-18 1991-02-19 Carmelo Lo Duca Protected needle syringe
US6016800A (en) * 1997-10-24 2000-01-25 Century; Theodore J. Intrapulmonary aerosolizer
EP1488758A1 (en) * 2003-06-18 2004-12-22 3M Espe Ag Dispensing cartridge
US20050049558A1 (en) * 2003-06-18 2005-03-03 Michael Knee Dispensing cartridge
US20090057338A1 (en) * 2003-06-18 2009-03-05 3M Innovative Properties Company Dispensing cartridge
US9005178B2 (en) 2003-06-18 2015-04-14 3M Innovative Properties Company Dispensing cartridge
US20130174518A1 (en) * 2010-09-24 2013-07-11 Terumo Kabushiki Kaisha Method of assembling medicament injection device

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Publication number Publication date Type
DE2335095A1 (en) 1974-01-31 application

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