US3892237A - Self-injecting syringe - Google Patents

Self-injecting syringe Download PDF

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Publication number
US3892237A
US3892237A US46160574A US3892237A US 3892237 A US3892237 A US 3892237A US 46160574 A US46160574 A US 46160574A US 3892237 A US3892237 A US 3892237A
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Grant
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Prior art keywords
ampoule
means
casing
member
glass
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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Inventor
Maurice Steiner
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Maurice Steiner
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053Media being expelled from injector by pressurised fluid or vacuum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2425Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67BAPPLYING CLOSURE MEMBERS TO BOTTLES JARS, OR SIMILAR CONTAINERS; OPENING CLOSED CONTAINERS
    • B67B7/00Hand- or power-operated devices for opening closed containers
    • B67B7/92Hand- or power-operated devices for opening closed containers by breaking, e.g. for ampoules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3145Filters incorporated in syringes

Abstract

An injecting device having a protecting casing and an empty plastic ampoule therein with a needle fitted onto the empty ampoule in such a manner that its canal is open into said ampoule. A glass ampoule containing the liquid to be injected is sealed inside the casing, and an inclined member is provided for breaking the end of the glass ampoule and filling the plastic ampoule with the liquid from the glass ampoule, and a releasable compression spring is used for ejecting through the needle the liquid of the plastics ampoule after it has been filled.

Description

United States Patent Steiner 1 1 July 1, 1975 1 1 SELF-INJECTING SYRINGE 1,143,897 10/1957 France 128/216 966.962 10/1950 France 128/218 G [761 lnvemo at??? gg'zg gg zf g dc 1.382.399 11/1964 France 128/272 [22] Flled; 1974 Primary Examiner-Richard A. Gaudet [2]] Appl. No.: 461,605 Assistant Examiner-J. C. McGowan Attorney, Agent, or Firm Marmaduke A. Hobbs [30] Foreign Application Priority Data July 17, 1973 France 73.26167 {57] ABSTRACT [52] [1.5. CI 128/216; 128/218 G An m ectmg device having a protecting casing and an [51] Int. Cl A6lm 5/24 1 I h d] r d 158 Field 6: Search 128/216, 215, 272, 218 F, 2" a 128/218 0,218 R173 H 218 NV 218 P onto e empty ampoue 1n sue a manner t at its canal 18 open mto said ampoule. A glass ampoule con- :1: 1 r UNITED STATES PATENTS ing the end of the glass ampoule and filling the plastic 2.871.856 2/1959 Steiner 128/216 ampeule i h h liq id from the glass ampoule, and :1 314001716 Schultz releasable compression spring is used for ejecting 222:2: 5 through the needle the liquid of the plastics ampoule after it has been filled.

FOREIGN PATENTS OR APPLICATIONS 1.133.507 7/1962 Germany 128/216 2 Claims, 6 Drawing Figures llk.

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SELF-INJECTING SYRINGE The present invention relates to injecting devices of the type comprising, on the one hand, a glass ampoule with a breakable tip containing a liquid to be injected and compressed gas, and, on the other hand, an hypodermic needle and communicating means between said needle and said glass ampoule.

In known devices, such communication is ensured through a flexible pipe, or a chamber defined by the device. casing itself.

These known devices are not permitting of an automatic working of the device.

The purpose of the present invention is an automatic working injection device preventing any risk for the patient and ensuring the stability and the purity of the conditioned product.

For this purpose, the injecting device according to the invention comprises a protecting casing, and inside this casing an empty plastics ampoule, a needle fitted onto said empty ampoule in such a manner that its canal is opening into said empty ampoule, a glass ampoule sealed inside the casing and containing the liquid to be injected, means to break the end of the glass am poule, means to provide for the filling of the ampoule of plastic material with the liquid coming out of the glass ampoule, mechanical resilient means for ejecting through the needle the liquid of the plastics ampoule after it has been filled up compressioning means for said mechanical resilient means and, outside said casing, means for releasing said resilient means.

By way of non limiting examples, three embodiments of the injecting device or injecting syringe according to the invention have been illustrated on the attached drawing, on which:

FIG. 1 is a longitudinal section view ofa first embodiment of the syringe.

FIG. 2 is a detailed view of a modification of the device in FIG. 1.

FIG. 3 is a detailed elevation view of a member in FIG. 2.

FIG. 4 is a plan view of the member in FIG. 3.

FIG. 5 is a longitudinal section view of another em bodiment of the syringe according to the invention and FIG. 6 is a plan view of a member of the syringe in FIG. 5.

In the example in FIG. 1, the syringe comprises a cylindrical casing, preferably of plastics, made of two parts, screwed for example, 1 and 2; the upper part 1 contains a tensioned spring 3 bearing, on the one hand, against the bottom of the casing, and on the other hand, against a member 11 of plastics material, the purpose of which will be explained hereafter.

A sealed glass ampoule 5, itself housed in a protecting tube 6 having an opened bottom, is housed in the space freed by the spring. This ampoule is of the selfbreaking type, i.e., to break its neck 7, it is but necessary to apply a pressure at its level. The liquid to be injected is contained in this ampoule together with a certain quantity 8 of compressed gas.

The end of the ampoule is capped with a tightly fitted pipe 10, made of rubber or similar material. This pipe is fitted at its lower end, onto the cylindrical projection provided therefor on the plastics member 11, the socalled piston, which is sliding with some play in the casing 2. A small filter 33, a cotton one for example, is arranged in the space provided between the tip 7 of the glass ampoule 5 and the member 11, so as to prevent, in the case when the breaking of the tip would result in glass spliting, the splits from being carried on into the ampoule l6.

The piston 11 comprises a canal l2 and a valve 13 of the ball type.

A frusto-conical member 14 is positioned, but not tightly fitted, in the corresponding frusto-conical part 15 of a plastics ampoule 16 having an accordion shape. The latter is fitted onto the support 17 of a bevelled needle 18 which is tightly engaged by friction, so as to ensure tightness, into a rubber stopper 19 which can be perforated and is accommodated in an opening provided at the lower portion of the casing.

The lower external portion 22 of casing 2 comprises a threading and two openings, having the shape of narrow slots diametrically opposite, are provided on the same member.

A milled nut 23, rigid with a member 24, adapted to rotate freely about this nut, is fitted onto this threading.

Member 24 has two lugs 26, 26' engaging the two slots 25. These two lugs are protruding inside the casing 2, sufficiently to stop the stroke of piston 11.

The protecting tube of ampoule 6 is stopped by a disc fitted therein 27 which is in contact with the end of a pusher 28 covering the upper end of the syringe and passing through the bottom of the latter.

This pusher shall necessarily be locked during the transport of the syringe by the user. The locking means is not shown on the drawing; this could be a mere pin.

The filter 33 is applied to the upper part which is in a bevelled position 29 of member 11.

The releasing device, of the type described in the US. Pat. No. 3,702,609 comprises hook-shaped members 30 and a ring 31. The ends 32, 32' of members 30 are holding the lower portion of member 11.

The working is as follows:

When the pusher 28 has been unlocked, the upper part of the syringe is grasped, and by applying uprightly the lower part onto a hard object, having an approximately horizontal part, and if necessary onto the ground, with interposition of a handkerchief, a sudden thrust is impelled to the pusher with the hand palm. After the combined protecting tube 6 and ampoule 5 have slid downward, the neck 7 is submitted to a force perpendicular to the axis, owing to the pitch of the upper face 29 of piston 11 and it breaks.

After waiting 2 or 3 seconds, that injection is made in the upper thigh, by applying the syringe and by pulling downward the ring 31. The ends 32, 32 of the members 30 open outwardly thus releasing piston 11. The latter, moved by the released spring 3, urges the combined ampoule 16 and needle 18 forward. The two conical parts 14 and 1S engage into each other, the valve 13 closes, the needle 18 pierces the stopper l9, enters into the flesh of the user and the crushing of ampoule [6 through the action of spring 3 injects the liquid.

The screwing or unscrewing of nut 23 enables the dose ofliquid to be injected to be determined by adjustment of the length of the piston stroke.

In addition, slots 25 permit to ascertain that the ampoule 16 is satisfactorily filled up during the operation.

In the example shown in FIGS. 2 and 4, the ball-valve in FIG. 1 is replaced by a merely mechanical means preferably of plastics made of a blade 34 comprising a narrow portion 35, called guide, a circular opening 36 of the same diameter as canal 12 of the member 29, a vent 37 and an end portion 38 with a flat-spring shape. This blade 34 is acting as a slide" and is housed by soft friction into a groove of same profile provided in the thickness of member 29. The portion 35 engages a slide provided in the thickness of the syringe wall. This slide 39 may, if desired, be provided in a thickening of same wall. its profile constituting, in the plastics molding technics, a counter-stripping" arrangement, this slide may be housed at the level of the connecting face of the two syringe portions.

The spring portion of the slide maintains the latter in a pre-determined position, i.e., with its opening 36 fit ting exactly canal l2, and with its vent 37 freeing a small canal 40 which enables the compressed gas to escape during the liquid transfer.

The working is as follows on the very moment of the release, the slide obturates at the same time, through a sliding movement along slide 39, and at the time when the spring tension begins to be applied to the accordion-ampoule, the canal l2 and vent 40.

The above process chosen for stopping the ampoule and for the gas escape, enables to secure in a proof arrangement, the pliable ampoule onto the member 29.

If the plastics ampoule is conveniently filled up, which is easy to obtain, as it is but necessary to provide for a quantity of liquid slightly in excess in the glass ampoule and the liquid contained in this ampoule will not escape, whatever the position of the syringe, due to the capillarity forces.

In the example shown in FIGS. 5 and 6, the syringe differs only from that in FIG. 1 by the use ofa releasing device 4 ensuring the breaking of tip 7 of the glass ampoule 5 as well as the releasing of spring 3. This spring is here bearing on the one hand against the bottom of casing 1 and on the other hand against this member 4.

This releasing device 4 has the shape of a fork, the two legs of which are gripping the combined tip 7 of the glass ampoule 5 and rubber pipe 10. A canal 21 is provided near the grasping ring 32 of the releasing device 4.

It is obvious that, to actuate the syringe in this embodiment, the user presses down the releasing device until it is flush with casing l, in taking hold ofit through ring 32. The end 7 of the ampoule is broken. The gas 8 urges the liquid into the ampoule l6, emptying the glass ampoule, and escapes outwards through the space provided for by the clearance between the piston ll and the wall, and through the canal 21 connecting the inside of the syringe to the outside.

The user waits a few seconds and then applies the bottom of the syringe to his body; he pulls off then the releasing device 4 by pulling on ring 32.

The spring 3 which is released strikes the piston 11 which urges forward the combined ampoule l6 and needle 18.

What I claim is:

1. An injecting device comprising a protecting casing, and inside this casing an empty plastics collapsible ampoule, a needle having a canal and fitted onto said empty ampoule, said needle canal opening into said empty ampoule, a glass ampoule sealed inside the casing and containing the liquid to be injected, means to break the end of the glass ampoule, means to provide for the filling of the collapsible ampoule with the liquid coming out of the glass ampoule, mechanical resilient means for both propelling said needle through said casing and ejecting through said needle the liquid of the collapsible ampoule by compressing said collapsible ampoule after it has been filled up, compressioning means for said mechanical resilient means, and outside said casing, means for releasing said resilient means.

2. An injecting device as in claim 1, wherein said means to provide for the filling of the collapsible ampoule comprises an obturating member for said empty ampoule slidably mounted in said casing and having an axial canal, a blade slidingly mounted in said obturating member and provided with a hole aligned with said axial canal, means urging said blade towards the outside of said obturating member, and means for urging said blade towards the inside of said obturating member when said resilient means are released.

Claims (2)

1. An injecting device comprising a protecting casing, and inside this casing an empty plastics collapsible ampoule, a needle having a canal and fitted onto said empty ampoule, said needle canal opening into said empty ampoule, a glass ampoule sealed inside the casing and containing the liquid to be injected, means to break the end of the glass ampoule, means to provide for the filling of the collapsible ampoule with the liquid coming out of the glass ampoule, mechanical resilient means for both propelling said needle through said casing and ejecting through said needle the liquid of the collapsible ampoule by compressing said collapsible ampoule after it has been filled up, compressioning means for said mechanical resilient means, and outside said casing, means for releasing said resilient means.
2. An injecting device as in claim 1, wherein said means to provide for the filling of the collapsible ampoule comprises an obturating member for said empty ampoule slidably mounted in said casing and having an axial canal, a blade slidingly mounted in said obturating member and provided with a hole aligned with said axial canal, means urging said blade towards the outside of said obturating member, and means for urging said blade towards tHe inside of said obturating member when said resilient means are released.
US3892237A 1973-07-17 1974-04-17 Self-injecting syringe Expired - Lifetime US3892237A (en)

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US4772271A (en) * 1985-08-13 1988-09-20 Medicorp Holding S.A. Prefilled syringe
USRE32922E (en) * 1983-01-13 1989-05-16 Paul D. Levin Blood sampling instrument
WO1994006690A1 (en) * 1992-09-21 1994-03-31 Habley Medical Technology Corporation Device and method for containing an ampule and transferring liquid within the ampule to a container
US5301381A (en) * 1992-12-07 1994-04-12 Klupt Michael F Toothbrush system
EP0694498A1 (en) 1994-07-28 1996-01-31 AVL Medical Instruments AG Method and device for transferring a liquid from a sealed glass ampoule
US5540709A (en) * 1991-11-12 1996-07-30 Actimed Laboratories, Inc. Lancet device
US5683369A (en) * 1994-04-12 1997-11-04 Tsukada Medical Research Co., Ltd. Bellows type container charged with liquid medicine
US5879336A (en) * 1995-03-13 1999-03-09 Vygon Device for injecting a liquid
US5948366A (en) * 1997-11-24 1999-09-07 Avl Medical Instruments Ag Glass ampoule for holding a drug a calibration liquid or a quality control liquid
JP2981616B2 (en) 1997-12-22 1999-11-22 アー・ファウ・エル・メディカル・インスツルメンツ・アー・ゲー Apparatus for extracting the contents from the glass ampoule
US6047865A (en) * 1996-07-24 2000-04-11 The Boc Group Plc Gas capsule and gas delivery system
EP1017485A1 (en) * 1997-07-29 2000-07-12 Stryker Technologies Corporation Apparatus for storing, mixing, and dispensing two-component bone cement
US6099532A (en) * 1998-07-13 2000-08-08 Howmedica Inc. Disposable monomer dispenser and vial breaker
GB2352233A (en) * 1999-07-17 2001-01-24 Anant Mohanal Ghelani Vial handling device
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US6379337B1 (en) * 1998-12-22 2002-04-30 Owais Mohammad M. B. B. S. Retractable safety needles for medical applications
US6391003B1 (en) 1999-10-25 2002-05-21 Antares Pharma, Inc. Locking mechanism for a jet injector
US6428528B2 (en) 1998-08-11 2002-08-06 Antares Pharma, Inc. Needle assisted jet injector
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US6516977B2 (en) * 1996-02-21 2003-02-11 Kwan-Ho Chan System and method for mixing bone cement
US6669671B1 (en) 1998-12-22 2003-12-30 Owais Mohammad Retractable needle with dual locking mechanisms
US6776775B1 (en) 1999-12-23 2004-08-17 Owais Mohammad Hypodermic syringe needle assembly and method of making the same
US20050107747A1 (en) * 2002-11-22 2005-05-19 Life-Shield Products, Inc. Retractable safe syringe
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US20130145727A1 (en) * 2010-07-07 2013-06-13 Heraeus Medical Gmbh Vacuum cementing system
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US8636704B2 (en) 2009-04-29 2014-01-28 Abbvie Biotechnology Ltd Automatic injection device
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Cited By (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE32922E (en) * 1983-01-13 1989-05-16 Paul D. Levin Blood sampling instrument
US4772271A (en) * 1985-08-13 1988-09-20 Medicorp Holding S.A. Prefilled syringe
US5540709A (en) * 1991-11-12 1996-07-30 Actimed Laboratories, Inc. Lancet device
US5393497A (en) * 1992-09-21 1995-02-28 Habley Medical Technology Corporation Device for containing and opening a glass ampule and for transferring liquid within the ampule to a container
WO1994006690A1 (en) * 1992-09-21 1994-03-31 Habley Medical Technology Corporation Device and method for containing an ampule and transferring liquid within the ampule to a container
US5301381A (en) * 1992-12-07 1994-04-12 Klupt Michael F Toothbrush system
US5321866A (en) * 1992-12-07 1994-06-21 Klupt Michael F Toothbrush system
US5683369A (en) * 1994-04-12 1997-11-04 Tsukada Medical Research Co., Ltd. Bellows type container charged with liquid medicine
EP0694498A1 (en) 1994-07-28 1996-01-31 AVL Medical Instruments AG Method and device for transferring a liquid from a sealed glass ampoule
US5628353A (en) * 1994-07-28 1997-05-13 Avl Medical Instruments Ag Method and device for withdrawing a liquid from a sealed glass ampoule
US5879336A (en) * 1995-03-13 1999-03-09 Vygon Device for injecting a liquid
US20030155381A1 (en) * 1996-02-21 2003-08-21 Kwan-Ho Chan System and method for mixing bone cement
US6516977B2 (en) * 1996-02-21 2003-02-11 Kwan-Ho Chan System and method for mixing bone cement
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DE2431347A1 (en) 1975-01-30 application
FR2237643A1 (en) 1975-02-14 application
FR2237643B1 (en) 1978-03-17 grant

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