New! View global litigation for patent families

US3882863A - Hypodermic injection device having cannula covered with resilient sheath - Google Patents

Hypodermic injection device having cannula covered with resilient sheath Download PDF

Info

Publication number
US3882863A
US3882863A US38468273A US3882863A US 3882863 A US3882863 A US 3882863A US 38468273 A US38468273 A US 38468273A US 3882863 A US3882863 A US 3882863A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
end
cannula
sheath
sleeve
cartridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Stanley J Sarnoff
George B Calkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Survival Technology Inc
SURVIVAL Technology
Original Assignee
SURVIVAL Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock

Abstract

A hypodermic injection device comprising a cartridge holder having a cylindrical body open at one end and closed at the other end, the closed end being provided with an aperture, a cartridge including an ampoule with attached cannula within the holder, the cannula being directed toward the holder''s closed end, the ampoule including a cylindrical sleeve slidably carrying a piston, the sleeve being open at one end and having a necked portion at the other end to receive a hub mounting the cannula, fluid medicament in the sleeve between the piston and cannula, a spring power assembly for moving the cartridge forward and for injecting the fluid medicament carried in the ampoule, a safety assembly for controlling actuation of the spring power assembly, and a resilient sheath covering the cannula to maintain the cannula in sterile condition.

Description

United States Patent 1191 Sarnoff et al.

[ ]*May 13, 1975 [54] HYPODERMIC INJECTION DEVICE 3,403,679 10/1968 Sinclair et a1. 128/218 F A COVERED WITH 3,702,609 11 1972 Steiner 128/218 F 3,712,301 1/1973 Sarnoff 128/218 F [75] Inventors: Stanley J. Sarnoff; George B. FOREIGN PATENTS OR APPLICATIONS Calkins, both f Bethesda Md 1,514,210 H1968 France 128/218 F [73] Assignee: Survival Technology, Inc., Bethesda, Primary Examiner Richard Gaudet Assistant Examiner-J. C. McGowan =1 1 Notice; The portion of the term of this Attorney, Agent, or Firm-Witherspoon and Lane patent subsequent to Mar. 19, 1991, has been disclaimed. 1 1 B RACT A hypodermic injection device comprising a cartridge 2 F A 1 73 2] fled 9 holder havmg a cylmdncal body open at one end and [21] Appl. No.: 384,682 closed at the other end, the closed end being provided with an aperture, a cartridge including an ampoule l. 12 with attached cannula Within the holder the cannula 4 5 5 being directed toward the holders closed end, the am- [58] Fie'ld 218 DA poule including a cylindrical sleeve slidably carrying a 128/218 NV M R piston, the sleeve being open at one end and having a 218 g necked portion at the other end to receive a hub mounting the cannula, fluid medicament in the sleeve between the piston and cannula, a spring power as- [56] References cued sembly for moving the cartridge forward and for in- UNITED STATES PATENTS jecting the fluid medicament carried in the ampoule, a 2,752,918 7/1956 Uytenbogaart 128/218 F afety assembly for controlling actuation of the spring 2,847,995 8/1958 Adams 128/218 N power assembly, and a resilient sheath Covering the ;6 cannula to maintain the cannula in sterile condition. 3:136:313 6/1964 EnstrBm et a1. 128/218 F 7 Claims, 3 Drawing Figures 2|4 lo I06 164 I38 I29 101 113 2 so 136 14s PATENTEU HAY 1 ems 882,863

HYPODERMIC INJECTION DEVICE HAVING CANNULA COVERED WITH RESILIENT SHEATH SUMMARY OF THE INVENTION This invention relates to injection devices of the gun type wherein spring power means drives an ampoule and cannula to insert the cannula and then inject the medicament. The cannula is provided with a resilient sheath to maintain the cannula in sterile condition at 'all times prior to injection.

In the device of this invention, the ampoule and attached cannula are slidably carried in a cylindrical holder which is closed at the end housing the cannula except for an aperture through which the cannula passes when the unit is actuated. A spring power assembly drives a plunger which engages the ampoule to drive the ampoule and cannula forward causing the cannula to travel out through the aperture in the closed end of the cylindrical holder and to enter the locus which is to receive the fluid medicament. Continued movement of the plunger, after placing of the cannula in the locus, forces a piston in the ampoule forwardly to inject the medicament. During this action, the resilient sheath positioned on and over the cannula is held within the closed end of the cylindrical holder and is pierced by the end of the cannula as it proceeds forwardly. As the cannula continues forward, the sheath is compressed between the closed end of the cylindrical holder and the cannula hub. This action continues until the cannula is fully extended, at which time the sheath is not quite fully compressed, thus making it possible for the sheath to act as a shock absorber at all times during forward travel of the cannula. Toward the end of injection, the forward travel of the power spring is such that its energy is less than that now stored in the compressed sheath. Therefore, a. slight retraction of the cannula occurs during the terminal portion of the injection.

In view of the foregoing, it is an object of this invention to provide a gun type injection device with a resilient cannula sheath for maintaining the cannula in sterile condition at all times prior to actuation.

It is another object of this invention to provide a gun type injection device with a resilient cannula sheath to act as a shock absorber during operation of the device.

It is a further object of this invention to provide a gun type injection device wherein the cannula is covered by a resilient sheath which upon being compressed when the device is actuated will react to retract the cannula a small distance during the terminal portion of injection.

IN THE DRAWINGS FIG. 1 is a longitudinal broken away view, partly in section, illustrating the sheath as applied to the cannula when the injection device is in ready position;

FIG. 2 is a view similar to FIG. 1, showing the compressed sheath after firing of the injection device with the cartridge fully projected and just prior to the forward movement of the plunger and injection of the medicament; and

FIG. 3 is a view similar to FIG. 2, illustrating a slight retraction of the cannula from the fully extended position of FIG. 2 which .retraction occurs during the terminal portion of the injection.

DETAILED DESCRIPTION OF THE INVENTION 0 open end. A cartridge assembly 106 is assembled in the shouldered end of the outer sleeve 100. The cartridge assembly 106 includes a cartridge holder sleeve 104 fitted within the sleeve 100 and having a decreased forward end portion 153 forming a shoulder 154 which fits against seat 112 provided by outer sleeve shoulder 110. The extreme forward end portion 156 of the holder sleeve 104 is tapered to form a small circular aperture.

The cartridge 135 includes an ampoule cylinder 136 with liquid medicament 146 there within and a piston 148 at one end with a cannula 150 at the other end. The ampoule cylinder 136 has a necked portion with a diameter less than that of the cylinder I36 and terminates in an enlarged annular flange. The cannula 150 is secured to a cannula hub 81 which in turn is affixed to the enlarged flange on the necked portion 80. More specifically, cannula hub 81 comprises a reduced diameter portion 84 which is secured to cannula 150 and an intermediate body 86 connected to enlarged body 88. The enlarged body 88 fits over and is secured to the annular flange of the necked portion 80 of the ampoule cylinder. Within the neck of the ampoule cylinder 136, between the inner end of the cannula 150 and the medicament, there may be interposed a fluid pressure rupturable diaphragm generally like that described in US. Pat. No. 3,391,695 to Sarnoff.

The cartridge assembly 106 is assembled in the outer sleeve with the cannula 150 spaced from the apertured end of the holder 104. The overall length of the ampoule and cannula is such that it is all contained within the holder sleeve 104, as illustrated in FIG. 1.

The outer sleeve 100 is of such length that it accommodates the cartridge assembly 106 in one end and receives the gun assembly 200 in the other to complete the device. The gun assembly 200 comprises an inner gun sleeve 101 having an out turned flange 103 which fits up against the end of the cartridge holder sleeve 104 when the gun assembly is inserted in the outer sleeve 100. The other end of the inner gun sleeve 101 is centrally apertured to form a hole 120. The rear outer face 122 of the inner gun sleeve 10] is planar and perpendicular to the longitudinal axis of the sleeve for a purpose to be brought out later.

A plunger 162 fits within the out turned flange end of the inner gun sleeve 101. This plunger has a cylindrical body portion 163 and a circular head portion 164 of a diameter larger than the body portion 163 and generally slightly less than that of the piston 148 in the ampoule 135. The head 164 has an opening which is sized to align and correspond to the through hole 166 in the plunger body 163. The plunger head 164 is provided with a plurality of circumferentially spaced, radially extending tabs 168. These tabs 168 form a diameter greater than that of the plunger head 164 so that the tabs will engage the end of the ampoule cylinder 136.

' Longitudinal slots 172 are formed in the plunger head 164 immediately behind the tabs 168. These slots are sized so that they will accommodate the tabs 168 when they are later broken off or bent rearwardly in the operation of the device. These slots extend throughout the length of the head behind the tabs.

Referring to FIGS. 1 and 2, a locking detent 176 is fitted through the hole 166 in the plunger 162 and has a central body portion 178 with outwardly extending lugs 180 on one end fitting an annular shoulder 182 of the plunger head 164. The other end of the locking detent 176 is provided with four equally spaced, longitudinally extending springy detent arms terminating in frusto-conical detent heads 186. This locking detent 176 maintains the plunger 162 and inner gun sleeve 101 in assembled position with a coil spring 138 compressed therebetween as follows: A coil spring 138 is positioned over the plunger body 163 and abuts the plunger head 164 at one end and the inner face of the end wall of the inner sleeve 101 at the other. Upon compressing of the coil spring 138 sufficiently, the detent heads 186 will be cammed inwardly by engaging the periphery of the end wall opening 120 and pass therethrough whereupon the bases of the detent heads 186 will come to rest on the planar face 122 of the inner gun sleeve 101 to retain the plunger and inner gun sleevein assembled condition with the coil spring 138 compressed therebetween. When desired, the rear planar surface 122 of the inner sleeve 101 may be overlaid with a metal washer 127, in which case it is advan tageous to provide a guide and holding flange 128 to surround the opening 120. The flange 128 is provided with a lip portion to retain the washer in place.

As illustrated in FIGS. 1 and 2, the inner gun sleeve 101 has a plurality of longitudinally extending raised ribs 129 running from the flange 103 approximately one-half the length of the said sleeve. An outer gun sleeve 192 fits over inner gun sleeve 101 and is sized to frictionally engage ribs 129. The outer sleeve 192 has a closed end 194 with a central aperture 196 from which extends a frusto-conical cam surface 198 sized and shaped to cooperate with frusto-conical detent heads 186 to cam said heads radially inwardly. The outer gun sleeve 192 is provided with a circumferential locking rib 199 which fits in groove 113 in the outer sleeve 102 to retain the gun assembly 200 in position in said outer sleeve. It should be noted that the length of outer gun sleeve 192 is slightly less than that of the inner gun sleeve 101 so as to make certain that there will be space between the inner wall of the outer gun sleeve 192 and the flange 103 of the inner gun sleeve 101 so that the two gun sleeves may move relative to each other to ca'm frusto-conical detent heads 186 inwardly in operating the device.

In order to make certain that the frusto-conical detent heads 186 are not accidentally cammed inwardly, a safety pin assembly is provided. This safety pin assembly comprises a cap 142 having a cylindrical sleeve 143 sized to fit over the end portion of outer gun sleeve 192. A safety pin 144 extends inwardly from the center of the cap 142 into the opening formed by the inner portions of the detent heads 186 to thereby prevent inward movement of said detent heads. The cap 142 is provided internally with a plurality of spacer abutments 145 to assure proper positioning of the cap on the outer abuts the shoulder 82 formed by hub portions 84 and 86. The length of the sheath is such that its closed end is slightly beyond or spaced from the end of cannula 150. In order to make certain that the sheathed cannula is maintained in proper alignment with aperture 158, a plurality of ribs 157 is formed on the inner face of tapered holder portion 156 surrounding said aperture. Thus, the end of the sheath 250 is held in necessary alignment by bearing against the converging section of the ribs 157.

Upon the actuation of the injection device, the cartridge assembly 106 moves forward whereby the sheath 250 is compressed between the cannula end of the cartridge holder sleeve 104 and the hub shoulder 82, as illustrated in FIG. 2. The cannula sheath, in being compressed, acts as a shock absorber to gradually absorb some of the energy provided by the power spring 138 as it drives the cartridge assembly 106 forward. It should be noted that at no time, even when the cannula is fully extended, is the sheath compressed to such an extent that it would act as a solid and thereby provide no shock absorbing in such a condition.

When the cannula 150 is fully extended as shown in FIG. 2, the cannula sheath 250 will be compressed the greatest amount hence the largest reactionary force will exist in the compressed sheath in such position. As illustrated in FIG. 2, the cartridge has completed its travel under the force of spring 138 and the forward movementaof piston 148 commences under the action of spring 138 to start the injection cycle. The size of the sheath is such that in the maximum compressed condition, as in FIG. 2, the forces stored in the sheath are greater than those in spring 138 when it has reached a point just short of full piston travel. At this point the compressed sheath 250 takes over and causes the cartridge 135 and attached cannula 150 to retract slightly, as shown in FIG. 3, while the last stage of injection takes place. It is at this stage that the forces of the compressed sheath and the spring 138 are counterbalanced.

The importance of the sheath 250 and its multiple features is even more important when consideration is taken of the fact that most of the ampoule cylinders (i.e. cylinder 136 of the device illustrated) are made of glass and hence are subject to breakage under certain amounts and types of shock. The shock absorbing feature enjoyed by the use of the cannula sheath of this invention contributes substantially to overall quality and reliability. Furthermore, the covering of the cannula with the sheath provides greater ease in assembly since it is not necessary to maintain any of the inner portions of the holder and associated elements in sterile condition.

The type of material from which the sheath 250 can be made varies substantially. Even so, the preferred material would be one having good resilient characteristics such as various types of rubber and synthetics. Shelf life is also important. By this it is meant that the material should retain its characteristics over a substantial period of time and under varied conditions.

What is claimed is:

1. In a hypodermic injection device comprising a gun, a cartridge holder in operative relationship to the gun, a cartridge within the holder, said gun comprising a sleeve open at one end thereof, a plunger positioned within the sleeve, spring power means acting on said plunger tending to move it out the open end of the sleeve, restraining means cooperating with said plunger to prevent plunger movement, safety means acting on said restraining means to render it inoperative, said cartridge holder comprising a hollow shell acting as a prolongation of the gun sleeve, said cartridge including an ampoule comprising a hollow cylindrical sleeve, a piston slidably positioned in one end thereof and means mounting a cannula extending from and closing off the other end, a fluid within the cylindrical sleeve between the piston and the cannula, the cartridge fitting within the cartridge holder with the free end of the cannula within the end of the holder remote from the gun, the improvement comprising:

a resilient sheath covering the cannula, said sheath having a closed end and an open end, the length of the sheath being sized such that when assembled on the cannula the closed end of the sheath is not pierced by the cannula end, and means for preventing forward movement of the closed end of the sheath whereby when the power means forces the cartridge forward the cannula will pierce the closed end of the sheath and deliver the fluid medicament from the ampoule sleeve.

2. The invention as set forth in claim 1 and wherein the resilient sheath comprises a resilient cylinder having a closed and an open end, the length of the sheath being sized such that the closed end thereof is spaced from the cannula end.

3. The invention as set forth in claim 1 and wherein the resilient sheath is so sized that upon forward movement of the cartridge, the sheath will be compressed between the cannula hub and the forward end of the cartridge holder and act as a shock absorber.

4. The invention as set forth in claim 3 and wherein the size of the resilient sheath is such that it is never fully compressed, even when the cartridge is fully extended.

5. The invention as set forth in claim 4 and wherein means are provided in the forward end of the cartridge holder for centrally positioning the closed end of the resilient sheath in the cartridge holder.

6. The invention as set forth in claim 1 and wherein the resilient sheath is so sized that when it is compressed by the full extension of the cartridge under action of the power means the reactionary energy stored in the compressed sheath will overcome the force of the power means and retract the cannula a small distance.

7. The invention as set forth in claim 3 and wherein

Claims (7)

1. In a hypodermic injection device comprising a gun, a cartridge holder in operative relationship to the gun, a cartridge within the holder, said gun comprising a sleeve open at one end thereof, a plunger positioned within the sleeve, spring power means acting on said plunger tending to move it out the open end of the sleeve, restraining means cooperating with said plunger to prevent plunger movement, safety means acting on said restraining means to render it inoperative, said cartridge holder comprising a hollow shell acting as a prolongation of the gun sleeve, said cartridge including an ampoule comprising a hollow cylindrical sleeve, a piston slidably positioned in one end thereof and means mounting a cannula extending from and closing off the other end, a fluid within the cylindrical sleeve between the piston and the cannula, the cartridge fitting within the cartridge holder with the free end of the cannula within the end of the holder remote from the gun, the improvement comprising: a resilient sheath covering the cannula, said sheath having a closed end and an oPen end, the length of the sheath being sized such that when assembled on the cannula the closed end of the sheath is not pierced by the cannula end, and means for preventing forward movement of the closed end of the sheath whereby when the power means forces the cartridge forward the cannula will pierce the closed end of the sheath and deliver the fluid medicament from the ampoule sleeve.
2. The invention as set forth in claim 1 and wherein the resilient sheath comprises a resilient cylinder having a closed and an open end, the length of the sheath being sized such that the closed end thereof is spaced from the cannula end.
3. The invention as set forth in claim 1 and wherein the resilient sheath is so sized that upon forward movement of the cartridge, the sheath will be compressed between the cannula hub and the forward end of the cartridge holder and act as a shock absorber.
4. The invention as set forth in claim 3 and wherein the size of the resilient sheath is such that it is never fully compressed, even when the cartridge is fully extended.
5. The invention as set forth in claim 4 and wherein means are provided in the forward end of the cartridge holder for centrally positioning the closed end of the resilient sheath in the cartridge holder.
6. The invention as set forth in claim 1 and wherein the resilient sheath is so sized that when it is compressed by the full extension of the cartridge under action of the power means the reactionary energy stored in the compressed sheath will overcome the force of the power means and retract the cannula a small distance.
7. The invention as set forth in claim 3 and wherein the cylindrical sleeve is made of glass.
US3882863A 1973-08-01 1973-08-01 Hypodermic injection device having cannula covered with resilient sheath Expired - Lifetime US3882863A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US3882863A US3882863A (en) 1973-08-01 1973-08-01 Hypodermic injection device having cannula covered with resilient sheath

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US3882863A US3882863A (en) 1973-08-01 1973-08-01 Hypodermic injection device having cannula covered with resilient sheath
NL7410081A NL160725C (en) 1973-08-01 1974-07-26 Automatic syringe.
DE19742436000 DE2436000C2 (en) 1973-08-01 1974-07-26
DK405374A DK154472C (en) 1973-08-01 1974-07-29 Injektionsproejte
GB3343074A GB1449986A (en) 1973-08-01 1974-07-29 Hypodermic syringe
ES428770A ES428770A1 (en) 1973-08-01 1974-07-30 Improvements introduced in a device for hypodermic injections cion.
BE147099A BE818268A (en) 1973-08-01 1974-07-30 Injection device
JP8759574A JPS5038983A (en) 1973-08-01 1974-08-01
FR7426748A FR2239258B1 (en) 1973-08-01 1974-08-01
JP14484982U JPS5892950U (en) 1973-08-01 1982-09-27

Publications (1)

Publication Number Publication Date
US3882863A true US3882863A (en) 1975-05-13

Family

ID=23518311

Family Applications (1)

Application Number Title Priority Date Filing Date
US3882863A Expired - Lifetime US3882863A (en) 1973-08-01 1973-08-01 Hypodermic injection device having cannula covered with resilient sheath

Country Status (9)

Country Link
US (1) US3882863A (en)
JP (2) JPS5038983A (en)
BE (1) BE818268A (en)
DE (1) DE2436000C2 (en)
DK (1) DK154472C (en)
ES (1) ES428770A1 (en)
FR (1) FR2239258B1 (en)
GB (1) GB1449986A (en)
NL (1) NL160725C (en)

Cited By (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4031893A (en) * 1976-05-14 1977-06-28 Survival Technology, Inc. Hypodermic injection device having means for varying the medicament capacity thereof
US4394863A (en) * 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
US4484910A (en) * 1983-12-21 1984-11-27 Survival Technology, Inc. Dual mode automatic injector
WO1986001120A1 (en) * 1984-08-08 1986-02-27 Survival Technology, Inc. Injection method and apparatus with electrical blood absorbing stimulation
US4624660A (en) * 1984-11-02 1986-11-25 Duphar International Research B.V. Automatic injection device
US4658830A (en) * 1984-08-08 1987-04-21 Survival Technology, Inc. Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms
US4678461A (en) * 1984-11-01 1987-07-07 Survival Technology, Inc. Automatic injector with improved glass container protector
US4723937A (en) * 1985-05-20 1988-02-09 Survival Technology, Inc. Plural dosage automatic injector with a by-pass fitment
US4795433A (en) * 1985-05-20 1989-01-03 Survival Technology, Inc. Automatic injector for emergency treatment
US4822340A (en) * 1985-10-11 1989-04-18 Duphar International Research B.V. Automatic injector
US4902279A (en) * 1988-10-05 1990-02-20 Autoject Systems Inc. Liquid medicament safety injector
DE4037418A1 (en) * 1989-11-28 1991-05-29 Glaxo Group Ltd Feeder for liquid drug
US5026349A (en) * 1988-10-05 1991-06-25 Autoject Systems Inc. Liquid medicament injector system
WO1991016094A1 (en) * 1990-04-12 1991-10-31 Survival Technology, Inc. Dispersion multi-chamber auto-injector
US5085641A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use auto-injector with improved cap structure
US5085642A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use autoinjector
US5092842A (en) * 1987-05-08 1992-03-03 Wilhelm Haselmeier Gmbh & Co. Injection device with a cocking element and a second setting element
US5102393A (en) * 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US5167632A (en) * 1992-01-24 1992-12-01 New Potency Products, Inc. Syringe
US5167641A (en) * 1991-05-29 1992-12-01 Arnis, Inc. Auto-retracting needle injector system
US5273544A (en) * 1991-06-13 1993-12-28 Duphar International Research B.V. Injection device
US5354286A (en) * 1993-12-07 1994-10-11 Survival Technology, Inc. Injection device having polyparaxylylene coated container
US5391151A (en) * 1991-01-15 1995-02-21 Survival Technology, Inc. Subcutaneous injector
US5405362A (en) * 1991-04-29 1995-04-11 The Board Of Regents For The University Of Texas System Interactive external defibrillation and drug injection system
JPH07308386A (en) * 1993-11-15 1995-11-28 Phase Medical Inc Safety device for inserting medical apparatus and protecting the same thereafter
US5478316A (en) * 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
EP0695554A2 (en) 1994-07-27 1996-02-07 Survival Technology, Inc. Automatic injector
US5599315A (en) * 1995-12-01 1997-02-04 Charles J. McPhee Syringe actuation device
US5800405A (en) * 1995-12-01 1998-09-01 I-Flow Corporation Syringe actuation device
WO1999020327A2 (en) 1997-10-21 1999-04-29 I-Flow Corporation Spring-actuated infusion syringe
US6629958B1 (en) * 2000-06-07 2003-10-07 Ronald P. Spinello Leak sealing needle
US6669673B2 (en) 1991-12-18 2003-12-30 Icu Medical, Inc. Medical valve
US20040002684A1 (en) * 1991-12-18 2004-01-01 Lopez George A. Fluid transfer device and method of use
US20040039337A1 (en) * 2002-08-21 2004-02-26 Letzing Michael Alexander Portable safety auto-injector
US6712794B2 (en) 2001-08-21 2004-03-30 Spinal Specialties, Inc. Apparatus for delivering a viscous liquid to a surgical site
US20040215151A1 (en) * 2001-07-28 2004-10-28 Jeremy Marshall Injection devices
US20050038392A1 (en) * 2003-08-11 2005-02-17 Becton, Dickinson And Company Medication delivery pen assembly with needle locking safety shield
US20050171477A1 (en) * 2002-05-23 2005-08-04 Seedlings Life Science Ventures Apparatus and method for rapid auto-injection of medication
US20050222539A1 (en) * 2004-03-30 2005-10-06 Pediamed Pharmaceuticals, Inc. Automatic injection device
US20050277895A1 (en) * 2000-08-02 2005-12-15 Becton, Dickinson And Company Pen needle and safety system
US20050283115A1 (en) * 2000-08-02 2005-12-22 Lucio Giambattista Pen needle and safety shield system
US20060178634A1 (en) * 2004-12-06 2006-08-10 Wyrick Ronald S Medicine injection devices and methods
US20070017533A1 (en) * 2004-12-06 2007-01-25 Washington Biotech Corporation Method and apparatus for delivering epinephrine
US20070203247A1 (en) * 2006-02-28 2007-08-30 Elaine Phillips Epinephrine dosing regimens
US20070293582A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US20080039789A1 (en) * 2004-12-06 2008-02-14 Wyrick Ronald E Medicine injection devices and methods
US20080051715A1 (en) * 2004-08-06 2008-02-28 Young Matthew E Automatic injector with kickback attenuation
US20080097312A1 (en) * 2006-10-18 2008-04-24 Wilmot John G Autoinjector with needle depth adapter
US7470258B2 (en) 2001-03-13 2008-12-30 Mdc Investment Holdings, Inc. Pre-filled safety vial injector
US20090270804A1 (en) * 2004-08-06 2009-10-29 Meridian Medical Technologies, Inc. Automatic injector with needle cover
US20090299278A1 (en) * 2006-05-03 2009-12-03 Lesch Jr Paul R Injector with adjustable dosing
US20100137791A1 (en) * 2008-12-02 2010-06-03 Sanofi-Aventis Deutschland Gmbh Drive assembly suitable for use in a medication delivery device an medication delivery device
US8002765B2 (en) 1995-12-15 2011-08-23 Icu Medical, Inc. Medical valve with fluid escape space
US20110213315A1 (en) * 2008-09-18 2011-09-01 Becton, Dickinson And Company Medical injector with slidable sleeve activation
US20110226646A1 (en) * 2004-12-06 2011-09-22 Wyrick Ronald E Kits Containing Medicine Injection Devices And Containers
EP2424594A1 (en) * 2009-04-29 2012-03-07 Abbott Biotechnology Ltd Automatic injection device
US8162887B2 (en) 2004-06-23 2012-04-24 Abbott Biotechnology Ltd. Automatic injection devices
US20120172814A1 (en) * 2009-06-01 2012-07-05 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US8366682B2 (en) 2009-03-04 2013-02-05 Washington Biotech Corporation Medicine injection apparatuses
US8679061B2 (en) 2006-06-30 2014-03-25 Abbvie Biotechnology Ltd Automatic injection device
US8708968B2 (en) 2011-01-24 2014-04-29 Abbvie Biotechnology Ltd. Removal of needle shields from syringes and automatic injection devices
US8758301B2 (en) 2009-12-15 2014-06-24 Abbvie Biotechnology Ltd Firing button for automatic injection device
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
US20150105733A1 (en) * 2013-10-10 2015-04-16 Ann M. Gilchrist Syringe-Assist Device and Method for Utilizing the Same
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US9180244B2 (en) 2010-04-21 2015-11-10 Abbvie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9265887B2 (en) 2011-01-24 2016-02-23 Abbvie Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9393367B2 (en) 2013-03-12 2016-07-19 Antares Pharma, Inc. Prefilled syringes and kits thereof
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9808582B2 (en) 2006-05-03 2017-11-07 Antares Pharma, Inc. Two-stage reconstituting injector
US9867949B2 (en) 2008-03-10 2018-01-16 Antares Pharma, Inc. Injector safety device

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5329638U (en) * 1976-08-19 1978-03-14
EP0072057B1 (en) * 1981-08-10 1988-02-10 Duphar International Research B.V Automatic injection syringe
US4530695A (en) * 1982-12-31 1985-07-23 N.J. Phillips Pty. Limited Injector
GB2132488B (en) * 1982-12-31 1986-07-30 Phillips Pty Ltd N J Injector for animal dosing
FR2539302B1 (en) * 1983-01-17 1986-03-14 Brunet Jean Louis Syringe for medical purposes
ES2024489B3 (en) * 1986-05-15 1992-03-01 Duphar Int Res B V autosampler.
DE3644984A1 (en) * 1986-07-01 1988-07-07 Eberhardt Schlueter Cartridge or ampoule for an injection device and automatic injection device
JPH0725952Y2 (en) * 1988-12-26 1995-06-14 株式会社トップ Injection device
DE9005419U1 (en) * 1990-05-12 1990-07-19 Nothdurft, Klaus, 7000 Stuttgart, De
EP0461693B1 (en) * 1990-06-13 1995-12-13 Duphar International Research B.V Flexible sealing member for injection device
GB9118204D0 (en) * 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
DE19819409A1 (en) 1998-04-30 1999-11-11 Schering Ag injection device
DE10036594A1 (en) 2000-07-27 2002-02-07 Pfeiffer Erich Gmbh & Co Kg Delivery unit, especially for pharmaceuticals, comprises a container composed of separate chambers which hold a media component, an actuating unit and a connection between the chambers
EP2698180A1 (en) * 2012-08-15 2014-02-19 Sanofi-Aventis Deutschland GmbH Autoinjector

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2752918A (en) * 1949-08-17 1956-07-03 Auguste Rooseboom Hypodermic injection apparatus
US2847995A (en) * 1954-08-23 1958-08-19 Becton Dickinson Co Transfusion needle sheath
US2866458A (en) * 1956-05-09 1958-12-30 Becton Dickinson Co Hypodermic assembly
US2888924A (en) * 1958-02-25 1959-06-02 Russell P Dunmire Hypodermic syringes
US3136313A (en) * 1954-10-27 1964-06-09 Astra Ab Automatic hypodermic syringe
US3403679A (en) * 1964-12-11 1968-10-01 Secr Defence Brit Hypodermic injection apparatus with a secondary capsule-collapsing means
US3702609A (en) * 1968-11-21 1972-11-14 Maurice Steiner Hypodermic syringes, in particular self-injecting syringes
US3712301A (en) * 1971-01-11 1973-01-23 Survival Technology Gun type hypodermic injector with rapid cartridge displacement within holder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795162A (en) * 1972-02-10 1973-08-08 Philips Nv Injektie-inrichting

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2752918A (en) * 1949-08-17 1956-07-03 Auguste Rooseboom Hypodermic injection apparatus
US2847995A (en) * 1954-08-23 1958-08-19 Becton Dickinson Co Transfusion needle sheath
US3136313A (en) * 1954-10-27 1964-06-09 Astra Ab Automatic hypodermic syringe
US2866458A (en) * 1956-05-09 1958-12-30 Becton Dickinson Co Hypodermic assembly
US2888924A (en) * 1958-02-25 1959-06-02 Russell P Dunmire Hypodermic syringes
US3403679A (en) * 1964-12-11 1968-10-01 Secr Defence Brit Hypodermic injection apparatus with a secondary capsule-collapsing means
US3702609A (en) * 1968-11-21 1972-11-14 Maurice Steiner Hypodermic syringes, in particular self-injecting syringes
US3712301A (en) * 1971-01-11 1973-01-23 Survival Technology Gun type hypodermic injector with rapid cartridge displacement within holder

Cited By (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2721545A1 (en) * 1976-05-14 1977-11-24 Philips Nv syringe
US4031893A (en) * 1976-05-14 1977-06-28 Survival Technology, Inc. Hypodermic injection device having means for varying the medicament capacity thereof
US4394863A (en) * 1981-10-23 1983-07-26 Survival Technology, Inc. Automatic injector with cartridge having separate sequentially injectable medicaments
WO1985002776A1 (en) * 1983-12-21 1985-07-04 Survival Technology, Inc. Dual mode automatic injector
US4484910A (en) * 1983-12-21 1984-11-27 Survival Technology, Inc. Dual mode automatic injector
US4832682A (en) * 1984-08-08 1989-05-23 Survival Technology, Inc. Injection method and apparatus with electrical blood absorbing stimulation
WO1986001120A1 (en) * 1984-08-08 1986-02-27 Survival Technology, Inc. Injection method and apparatus with electrical blood absorbing stimulation
US4658830A (en) * 1984-08-08 1987-04-21 Survival Technology, Inc. Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms
US4678461A (en) * 1984-11-01 1987-07-07 Survival Technology, Inc. Automatic injector with improved glass container protector
US4624660A (en) * 1984-11-02 1986-11-25 Duphar International Research B.V. Automatic injection device
US4795433A (en) * 1985-05-20 1989-01-03 Survival Technology, Inc. Automatic injector for emergency treatment
US4723937A (en) * 1985-05-20 1988-02-09 Survival Technology, Inc. Plural dosage automatic injector with a by-pass fitment
US4822340A (en) * 1985-10-11 1989-04-18 Duphar International Research B.V. Automatic injector
US5092842A (en) * 1987-05-08 1992-03-03 Wilhelm Haselmeier Gmbh & Co. Injection device with a cocking element and a second setting element
US4902279A (en) * 1988-10-05 1990-02-20 Autoject Systems Inc. Liquid medicament safety injector
US5026349A (en) * 1988-10-05 1991-06-25 Autoject Systems Inc. Liquid medicament injector system
US5085642A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use autoinjector
US5102393A (en) * 1989-07-17 1992-04-07 Survival Technology, Inc. Autoinjector converted from intramuscular to subcutaneous mode of injection
US5085641A (en) * 1989-07-17 1992-02-04 Survival Technology, Inc. Conveniently carried frequent use auto-injector with improved cap structure
DE4037418A1 (en) * 1989-11-28 1991-05-29 Glaxo Group Ltd Feeder for liquid drug
US5137516A (en) * 1989-11-28 1992-08-11 Glaxo Group Limited Triggered application device for medicament to be more descriptive of the invention
DE4037418C2 (en) * 1989-11-28 1998-01-29 Glaxo Group Ltd Feeder for liquid medicines
US5092843A (en) * 1990-04-12 1992-03-03 Survival Technology, Inc. Dispersion multichamber auto-injector
WO1991016094A1 (en) * 1990-04-12 1991-10-31 Survival Technology, Inc. Dispersion multi-chamber auto-injector
US5391151A (en) * 1991-01-15 1995-02-21 Survival Technology, Inc. Subcutaneous injector
US5405362A (en) * 1991-04-29 1995-04-11 The Board Of Regents For The University Of Texas System Interactive external defibrillation and drug injection system
US5167641A (en) * 1991-05-29 1992-12-01 Arnis, Inc. Auto-retracting needle injector system
WO1992021395A1 (en) * 1991-05-29 1992-12-10 Arnis, Inc. Auto-retracting needle injector system
US5273544A (en) * 1991-06-13 1993-12-28 Duphar International Research B.V. Injection device
US7717885B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7713247B2 (en) 1991-12-18 2010-05-11 Icu Medical, Inc. Medical valve and method of use
US7713249B2 (en) 1991-12-18 2010-05-11 Icu Medical, Inc. Medical valve and method of use
US7717884B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7717883B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7713248B2 (en) 1991-12-18 2010-05-11 Icu Medical, Inc. Medical valve and method of use
US7717886B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US7717887B2 (en) 1991-12-18 2010-05-18 Icu Medical, Inc. Medical valve and method of use
US20040243070A1 (en) * 1991-12-18 2004-12-02 Lopez George A. Medical valve and method of use
US7722576B2 (en) 1991-12-18 2010-05-25 Icu Medical, Inc. Medical valve and method of use
US6669673B2 (en) 1991-12-18 2003-12-30 Icu Medical, Inc. Medical valve
US20040002684A1 (en) * 1991-12-18 2004-01-01 Lopez George A. Fluid transfer device and method of use
US6682509B2 (en) 1991-12-18 2004-01-27 Icu Medical, Inc. Medical valve and method of use
US6758833B2 (en) 1991-12-18 2004-07-06 Icu Medical, Inc. Medical value
US7722575B2 (en) 1991-12-18 2010-05-25 Icu Medical, Inc. Medical valve and method of use
US5167632A (en) * 1992-01-24 1992-12-01 New Potency Products, Inc. Syringe
JPH07308386A (en) * 1993-11-15 1995-11-28 Phase Medical Inc Safety device for inserting medical apparatus and protecting the same thereafter
US5354286A (en) * 1993-12-07 1994-10-11 Survival Technology, Inc. Injection device having polyparaxylylene coated container
US5478316A (en) * 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
EP0695554A2 (en) 1994-07-27 1996-02-07 Survival Technology, Inc. Automatic injector
US5599315A (en) * 1995-12-01 1997-02-04 Charles J. McPhee Syringe actuation device
US5800405A (en) * 1995-12-01 1998-09-01 I-Flow Corporation Syringe actuation device
US8002765B2 (en) 1995-12-15 2011-08-23 Icu Medical, Inc. Medical valve with fluid escape space
US6019747A (en) * 1997-10-21 2000-02-01 I-Flow Corporation Spring-actuated infusion syringe
WO1999020327A2 (en) 1997-10-21 1999-04-29 I-Flow Corporation Spring-actuated infusion syringe
US6629958B1 (en) * 2000-06-07 2003-10-07 Ronald P. Spinello Leak sealing needle
US20050283115A1 (en) * 2000-08-02 2005-12-22 Lucio Giambattista Pen needle and safety shield system
US7666164B2 (en) 2000-08-02 2010-02-23 Becton, Dickinson And Company Pen needle and safety shield system
US20050277895A1 (en) * 2000-08-02 2005-12-15 Becton, Dickinson And Company Pen needle and safety system
US7314464B2 (en) 2000-08-02 2008-01-01 Becton, Dickinson And Company Pen needle and safety system
US7470258B2 (en) 2001-03-13 2008-12-30 Mdc Investment Holdings, Inc. Pre-filled safety vial injector
US20100121272A1 (en) * 2001-07-28 2010-05-13 Owen Mumford Limted Relating to injection devices
US7695453B2 (en) 2001-07-28 2010-04-13 Owen Mumford Limited Injection devices
US20040215151A1 (en) * 2001-07-28 2004-10-28 Jeremy Marshall Injection devices
US8449498B2 (en) 2001-07-28 2013-05-28 Owen Mumford Limited Relating to injection devices
US6712794B2 (en) 2001-08-21 2004-03-30 Spinal Specialties, Inc. Apparatus for delivering a viscous liquid to a surgical site
US9737670B2 (en) 2002-02-11 2017-08-22 Antares Pharma, Inc. Intradermal injector
US9333309B2 (en) 2002-02-11 2016-05-10 Antares Pharma, Inc. Intradermal injector
US7658724B2 (en) 2002-05-23 2010-02-09 Seedings Life Science Ventures LLC Apparatus and method for rapid auto-injection of medication
US6979316B1 (en) 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
US20050171477A1 (en) * 2002-05-23 2005-08-04 Seedlings Life Science Ventures Apparatus and method for rapid auto-injection of medication
US20040039337A1 (en) * 2002-08-21 2004-02-26 Letzing Michael Alexander Portable safety auto-injector
US8932264B2 (en) 2003-08-11 2015-01-13 Becton, Dickinson And Company Medication delivery pen assembly with needle locking safety shield
US20050038392A1 (en) * 2003-08-11 2005-02-17 Becton, Dickinson And Company Medication delivery pen assembly with needle locking safety shield
US20050222539A1 (en) * 2004-03-30 2005-10-06 Pediamed Pharmaceuticals, Inc. Automatic injection device
US8162887B2 (en) 2004-06-23 2012-04-24 Abbott Biotechnology Ltd. Automatic injection devices
US9764090B2 (en) 2004-06-23 2017-09-19 Abbvie Biotechnology Ltd Relating to automatic injection devices
US9017287B2 (en) 2004-06-23 2015-04-28 Abbvie Biotechnology Ltd Automatic injection devices
US8668670B2 (en) 2004-06-23 2014-03-11 Abbvie Biotechnology Ltd Automatic injection devices
US9586010B2 (en) 2004-08-06 2017-03-07 Meridian Medical Technologies, Inc. Automatic injector with needle cover
US20090270804A1 (en) * 2004-08-06 2009-10-29 Meridian Medical Technologies, Inc. Automatic injector with needle cover
US20100318037A1 (en) * 2004-08-06 2010-12-16 Meridian Medical Technologies, Inc. Automatic injector
US8870827B2 (en) 2004-08-06 2014-10-28 Meridian Medical Technologies, Inc. Automatic injector
US8048035B2 (en) 2004-08-06 2011-11-01 Meridian Medical Technologies, Inc. Automatic injector with needle cover
US20110137247A1 (en) * 2004-08-06 2011-06-09 Meridian Medical Technologies, Inc. Automatic injector with needle cover
US7794432B2 (en) 2004-08-06 2010-09-14 Meridian Medical Technologies, Inc. Automatic injector with kickback attenuation
US20080051715A1 (en) * 2004-08-06 2008-02-28 Young Matthew E Automatic injector with kickback attenuation
US20080132838A1 (en) * 2004-12-06 2008-06-05 Washington Biotech Corporation Methods for injecting medicines to a desired depth
US7905352B2 (en) 2004-12-06 2011-03-15 Washington Biotech Corporation Kits containing medicine injection devices and containers
US7927303B2 (en) 2004-12-06 2011-04-19 Washington Biotech Corporation Medicine injection devices and methods
US20080039789A1 (en) * 2004-12-06 2008-02-14 Wyrick Ronald E Medicine injection devices and methods
US20100094217A1 (en) * 2004-12-06 2010-04-15 Wyrick Ronald E Methods Performed by Medicine Injection Apparatuses
US20060178634A1 (en) * 2004-12-06 2006-08-10 Wyrick Ronald S Medicine injection devices and methods
US8187224B2 (en) 2004-12-06 2012-05-29 Washington Biotech Corporation Methods performed by medicine injection apparatuses
US20070017533A1 (en) * 2004-12-06 2007-01-25 Washington Biotech Corporation Method and apparatus for delivering epinephrine
US7931618B2 (en) 2004-12-06 2011-04-26 Washington Biotech Corporation Apparatuses and methods for injecting medicines to a desired depth
US20100100039A1 (en) * 2004-12-06 2010-04-22 Wyrick Ronald E Medicine Injection Apparatuses
US20110226646A1 (en) * 2004-12-06 2011-09-22 Wyrick Ronald E Kits Containing Medicine Injection Devices And Containers
US9629959B2 (en) 2005-01-24 2017-04-25 Antares Pharma, Inc. Prefilled syringe jet injector
US9180259B2 (en) 2005-01-24 2015-11-10 Antares Pharma, Inc. Prefilled syringe jet injector
US20070203247A1 (en) * 2006-02-28 2007-08-30 Elaine Phillips Epinephrine dosing regimens
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US20090299278A1 (en) * 2006-05-03 2009-12-03 Lesch Jr Paul R Injector with adjustable dosing
US9808582B2 (en) 2006-05-03 2017-11-07 Antares Pharma, Inc. Two-stage reconstituting injector
US20070293582A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
US8679061B2 (en) 2006-06-30 2014-03-25 Abbvie Biotechnology Ltd Automatic injection device
US9486584B2 (en) 2006-06-30 2016-11-08 Abbvie Biotechnology Ltd. Automatic injection device
US20100292643A1 (en) * 2006-10-18 2010-11-18 Meridian Medical Technologies, Inc. Autoinjector With Needle Depth Adapter
US20080097312A1 (en) * 2006-10-18 2008-04-24 Wilmot John G Autoinjector with needle depth adapter
US7811254B2 (en) 2006-10-18 2010-10-12 Meridian Medical Technologies, Inc. Autoinjector with needle depth adapter
US9867949B2 (en) 2008-03-10 2018-01-16 Antares Pharma, Inc. Injector safety device
US9561333B2 (en) 2008-08-05 2017-02-07 Antares Pharma, Inc. Multiple dosage injector
US9901681B2 (en) * 2008-09-18 2018-02-27 Becton, Dickinson And Company Medical injector with slidable sleeve activation
US20110213315A1 (en) * 2008-09-18 2011-09-01 Becton, Dickinson And Company Medical injector with slidable sleeve activation
US9545483B2 (en) * 2008-12-02 2017-01-17 Sanofi-Aventis Deutschland Gmbh Drive assembly suitable for use in a medication delivery device and medication delivery device
US20100137791A1 (en) * 2008-12-02 2010-06-03 Sanofi-Aventis Deutschland Gmbh Drive assembly suitable for use in a medication delivery device an medication delivery device
US9731079B2 (en) * 2008-12-02 2017-08-15 Sanofi-Aventis Deutschland Gmbh Drive assembly suitable for use in a medication delivery device and medication delivery device
US20120083745A1 (en) * 2008-12-02 2012-04-05 Sanofi-Aventis Deutschland Gmbh Drive assembly suitable for use in a medication delivery device and medication delivery device
US8366682B2 (en) 2009-03-04 2013-02-05 Washington Biotech Corporation Medicine injection apparatuses
US9265886B2 (en) 2009-03-04 2016-02-23 Washington Biotech Corporation Medicine injection apparatuses
US9750881B2 (en) 2009-03-20 2017-09-05 Antares Pharma, Inc. Hazardous agent injection system
US8945063B2 (en) 2009-03-20 2015-02-03 Antares Pharma, Inc. Hazardous agent injection system
EP2424594A4 (en) * 2009-04-29 2014-12-24 Abbvie Biotechnology Ltd Automatic injection device
EP2424594A1 (en) * 2009-04-29 2012-03-07 Abbott Biotechnology Ltd Automatic injection device
US9561328B2 (en) 2009-04-29 2017-02-07 Abbvie Biotechnology Ltd Automatic injection device
US8636704B2 (en) 2009-04-29 2014-01-28 Abbvie Biotechnology Ltd Automatic injection device
US20120209212A1 (en) * 2009-06-01 2012-08-16 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US9616179B2 (en) * 2009-06-01 2017-04-11 Sanofi—Aventis Deutschland GmbH Resetting mechanism for a drug delivery device
US9662454B2 (en) * 2009-06-01 2017-05-30 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US20120172814A1 (en) * 2009-06-01 2012-07-05 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US20120209211A1 (en) * 2009-06-01 2012-08-16 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US9517310B2 (en) * 2009-06-01 2016-12-13 Sanofi-Aventis Deutschland Gmbh Pen injector with resetting mechanism for receiving new cartridge during driver decoupling and proximal spindle retraction
US20120209210A1 (en) * 2009-06-01 2012-08-16 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US9687613B2 (en) * 2009-06-01 2017-06-27 Sanofi-Aventis Deutschland Gmbh Resetting mechanism for a drug delivery device
US8758301B2 (en) 2009-12-15 2014-06-24 Abbvie Biotechnology Ltd Firing button for automatic injection device
US9821117B2 (en) 2010-04-21 2017-11-21 Abbvie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
US9180244B2 (en) 2010-04-21 2015-11-10 Abbvie Biotechnology Ltd Wearable automatic injection device for controlled delivery of therapeutic agents
US8708968B2 (en) 2011-01-24 2014-04-29 Abbvie Biotechnology Ltd. Removal of needle shields from syringes and automatic injection devices
US9339610B2 (en) 2011-01-24 2016-05-17 Abbvie Biotechnology Ltd Removal of needle shield from syringes and automatic injection devices
US9265887B2 (en) 2011-01-24 2016-02-23 Abbvie Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
US9878102B2 (en) 2011-01-24 2018-01-30 Abbvie Biotechnology Ltd. Automatic injection devices having overmolded gripping surfaces
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US9446195B2 (en) 2011-07-15 2016-09-20 Antares Pharma, Inc. Injection device with cammed ram assembly
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
US9744302B2 (en) 2013-02-11 2017-08-29 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9707354B2 (en) 2013-03-11 2017-07-18 Antares Pharma, Inc. Multiple dosage injector with rack and pinion dosage system
US9393367B2 (en) 2013-03-12 2016-07-19 Antares Pharma, Inc. Prefilled syringes and kits thereof
US20150105733A1 (en) * 2013-10-10 2015-04-16 Ann M. Gilchrist Syringe-Assist Device and Method for Utilizing the Same
US9168562B2 (en) * 2013-10-10 2015-10-27 Ann Gilchrist Syringe-assist device and method for utilizing the same

Also Published As

Publication number Publication date Type
DK405374A (en) 1975-03-24 application
FR2239258B1 (en) 1981-12-24 grant
DK154472C (en) 1989-04-10 grant
JPS5038983A (en) 1975-04-10 application
BE818268A (en) 1975-01-30 grant
NL160725B (en) 1979-07-16 application
DK154472B (en) 1988-11-21 grant
JPS5892950U (en) 1983-06-23 application
FR2239258A1 (en) 1975-02-28 application
NL7410081A (en) 1975-02-04 application
BE818268A1 (en) grant
NL160725C (en) 1979-12-17 grant
GB1449986A (en) 1976-09-15 application
ES428770A1 (en) 1977-01-16 application
DE2436000A1 (en) 1975-02-13 application
DE2436000C2 (en) 1983-10-13 grant

Similar Documents

Publication Publication Date Title
US3583399A (en) Self-aspirating syringe
US3144178A (en) Cartridge holder
US3136313A (en) Automatic hypodermic syringe
US3425413A (en) Multi-dosage jet injector
US4089334A (en) Pyrotechnically powered needleless injector
US5578015A (en) Safety syringe incorporating automatic needle holder release
US5620421A (en) Syringe injector system
US5085641A (en) Conveniently carried frequent use auto-injector with improved cap structure
US6689093B2 (en) Single-use needle-less hypodermic jet injection apparatus and method
US5531694A (en) Needle retraction system
US5215533A (en) Safety syringe incorporating vacuum retraction of the needle
US3976069A (en) Injection syringe with cartridge retaining tab
US6558357B1 (en) Hypodermic syringe with selectively retractable needle
US4226235A (en) Plural injecting device
US2866458A (en) Hypodermic assembly
US5395337A (en) Needle retraction system
US6290679B1 (en) Device for metered administration of an injectable product
US5071353A (en) Training device for an automatic injector
US5295965A (en) Automatic injectors
US4955870A (en) Hypodermic syringe with retractable needle
US6692469B1 (en) Injection devices
US5342308A (en) Single-use syringe with retractable needle
US6752781B2 (en) Durable hypodermic jet injector apparatus and method
US4820275A (en) Retractable needle syringe with integral spring
US4518384A (en) Multiple medicament cartridge clip and medicament discharging device therefor

Legal Events

Date Code Title Description
AS Assignment

Owner name: FIRST PENNSYLVANIA BANK N.A.

Free format text: SECURITY INTEREST;ASSIGNOR:SURVIVAL TECHNOLOGY, INC., A DE CORP.;REEL/FRAME:005126/0187

Effective date: 19890323

AS Assignment

Owner name: SURVIVAL TECHNOLOGY, INC., MARYLAND

Free format text: RELEASED BY SECURED PARTY;ASSIGNOR:FIRST PENNSYLVANIA BANK N.A.;REEL/FRAME:005456/0252

Effective date: 19900914

AS Assignment

Owner name: SURVIVAL TECHNOLOGY INC., MARYLAND

Free format text: RELEASE BY SECURED PARTY;ASSIGNOR:ESTATE OF STANLEY J. SARNOFF C/O ROBERT E. HERZSTEIN SHEARMAN & STERLING;REEL/FRAME:006782/0360

Effective date: 19931109