US3851817A - Method and means for centrifuging chilled blood samples - Google Patents

Method and means for centrifuging chilled blood samples Download PDF

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US3851817A
US3851817A US00364954A US36495473A US3851817A US 3851817 A US3851817 A US 3851817A US 00364954 A US00364954 A US 00364954A US 36495473 A US36495473 A US 36495473A US 3851817 A US3851817 A US 3851817A
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receptacle
liquid
holder element
wall
container
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E Buck
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B15/00—Other accessories for centrifuges
    • B04B15/02—Other accessories for centrifuges for cooling, heating, or heat insulating

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  • ABSTRACT Primary Examiner-George l-I. Krizmanich Attorney, Agent, or Firm-Zarley, McKee, Thomte & Voorhees [57] ABSTRACT
  • the method comprises the steps of taking a receptacle having a double wall configuration with a space therebetween. The space between the double walls is filled with a liquid and the liquid is then frozen. The test liquid specimen is placed in a container and the c0ntainer is placed in the receptacle. The receptacle is then subjected to rotational movement while maintaining the container in close proximity to the inner wall of the receptacle so that the temperature of the test liquid will be reduced from its ambient temperature.
  • the means for centrifuging the chilled blood sample comprises a receptacle holder element having a double wall configuration with a space therebetween.
  • Refrigerant is positioned between the double walls so that the holder element may be placed in a cold environment to freeze the refrigerant.
  • the holder element is adapted to receive a test tube or the like containing the test specimen of liquid to be centrifuged.
  • the configuration of the double walls are such that the receptacle may be placed in close proximity to the inner wall of the holder element so as to permit the refrigerant material to reduce the ambient temperature of the test specimen.
  • a further object of the invention is to provide a means for centrifuging chilled blood samples comprising a double walled receptacle having a refrigerant positioned between the double walls which may be frozen.
  • a further object of the invention is to provide a means for centrifuging chilled blood samples comprising a holder element adapted to receive a test tube therein.
  • a further object of the invention is to provide a method for centrifuging chilled blood samples which eliminates the need of a refrigerated centrifuge.
  • a further object of the invention is to provide a method for centrifuging chilled blood samples which I eliminates the need for maintaining the centrifuge in a chilled atmosphere.
  • a further object of the invention is to provide a method and means for centrifuging chilled blood samples which is economical of manufacture, and durable in use.
  • FIG. 1 is a side view of the receptacle:
  • FIG. 2 is a side view of the receptacle having a test tube mounted therein:
  • FIG. 3 is a sectional view as seen on lines 3 3 of FIG. 2;
  • FIG. 4 is a side elevational view of a centrifuge which is employed with the receptacle of FIGS. 1 3.
  • the numeral 10 refers generally to a conventional centrifuge having a motor 12 positioned in the base 14.
  • Drive shaft 16 extends upwardly from the to outer wall 24 at the upper ends thereof.
  • Space 28 is filled with a re-freezable liquid or semi-solid substance generally referred to by the reference numeral 30.
  • the numeral 32 refers to a test tube or the like which may be inserted into the interior of the receptacle 22 through the open end 34. As seen in FIG. 2, the lip 36 of the test tube 32 engages the tapered upper portion of the inner wall 26. As seen in the drawings, the wall 38 of the test tube is in close proximity to the inner wall 26. v
  • the normal method of operation is as follows.
  • the receptacle 22 is placed in a freezer or the like to freeze or chill the material 30 in the space 28.
  • the test tube 32 may be filled with the blood sample and placed in the receptacle as illustrated in FIG. 2.
  • the receptacle and the test tube would then be placed in the metal cup-like support member 20.
  • the cover of the centrifuge would be closed and the motor 12 energized to centrifuge the blood sample for the proper period of time. It is quite important to note that the wall 38 of the test tube 32 is maintained in close proximity to the inner wall 26 so that the frozen or chilled material 30 will reduce the ambient temperature of the blood sample.
  • the method and means described herein eliminates the need for providing a refrigerated centrifuge and also it eliminates the need for maintaining the centrifuge in an environment having a substantially reduced temperature. While the apparatus has been described as being particularly well-adapted for centrifuging chilled blood samples, it should be noted that the apparatus could be used to chill any types of test specimens requiring reduced temperatures during the centrifuging thereof. Thus it can be seen that the method and means accomplishes at least all of the stated objectives.
  • centrifuge device having at least one supporting means secured to a rotating member and being adapted to support a receptacle during rotation of said supporting means
  • a receptacle holder element on said supporting means said holder element comprising inner and outer walls having a space therebetween,

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Abstract

The method comprises the steps of taking a receptacle having a double wall configuration with a space therebetween. The space between the double walls is filled with a liquid and the liquid is then frozen. The test liquid specimen is placed in a container and the container is placed in the receptacle. The receptacle is then subjected to rotational movement while maintaining the container in close proximity to the inner wall of the receptacle so that the temperature of the test liquid will be reduced from its ambient temperature. The means for centrifuging the chilled blood sample comprises a receptacle holder element having a double wall configuration with a space therebetween. Refrigerant is positioned between the double walls so that the holder element may be placed in a cold environment to freeze the refrigerant. The holder element is adapted to receive a test tube or the like containing the test specimen of liquid to be centrifuged. The configuration of the double walls are such that the receptacle may be placed in close proximity to the inner wall of the holder element so as to permit the refrigerant material to reduce the ambient temperature of the test specimen.

Description

United States Patent [19] Buck [111' 3,851,817 Dec. 3, 1974 METHOD AND MEANS FOR CENTRIFUGING CHILLED BLOOD SAMPLES [76] inventor: Eleanor S. Buck, 726 50th St., Des
Moines, Iowa 50312 [22] Filed: May 29, 1973 21 Appl. No.: 364,954
Primary Examiner-George l-I. Krizmanich Attorney, Agent, or Firm-Zarley, McKee, Thomte & Voorhees [57] ABSTRACT The method comprises the steps of taking a receptacle having a double wall configuration with a space therebetween. The space between the double walls is filled with a liquid and the liquid is then frozen. The test liquid specimen is placed in a container and the c0ntainer is placed in the receptacle. The receptacle is then subjected to rotational movement while maintaining the container in close proximity to the inner wall of the receptacle so that the temperature of the test liquid will be reduced from its ambient temperature. The means for centrifuging the chilled blood sample comprises a receptacle holder element having a double wall configuration with a space therebetween. Refrigerant is positioned between the double walls so that the holder element may be placed in a cold environment to freeze the refrigerant. The holder element is adapted to receive a test tube or the like containing the test specimen of liquid to be centrifuged. The configuration of the double walls are such that the receptacle may be placed in close proximity to the inner wall of the holder element so as to permit the refrigerant material to reduce the ambient temperature of the test specimen.
5 Claims, 4 Drawing Figures PATENIEQEEC 31974 METHOD AND MEANS FOR CENTRIFUGING CHILLED BLOOD SAMPLES BACKGROUND OF THE INVENTION This invention relates to a method and means for centrifuging chilled blood samples. There are many laboratory tests which require that chilled blood be centrifuged. The present method of chilling the blood samples is to either place the blood sample in a refrigerated centrifuge or to maintain the centrifuge in a chilled atmosphere. Obviously, the cost of manufacturing a chilled centrifuge is quite expensive as is the need for maintaining a chilled atmosphere around a centrifuge.
Therefore, it is a principal object of the invention to provide a method and means for centrifuging chilled blood samples.
A further object of the invention is to provide a means for centrifuging chilled blood samples comprising a double walled receptacle having a refrigerant positioned between the double walls which may be frozen.
A further object of the invention is to provide a means for centrifuging chilled blood samples comprising a holder element adapted to receive a test tube therein.
A further object of the invention is to provide a method for centrifuging chilled blood samples which eliminates the need of a refrigerated centrifuge.
A further object of the invention is to provide a method for centrifuging chilled blood samples which I eliminates the need for maintaining the centrifuge in a chilled atmosphere.
A further object of the invention is to provide a method and means for centrifuging chilled blood samples which is economical of manufacture, and durable in use.
These and other objects will be apparent to those skilled in the art.
BRIEF DESCRIPTION OF THE DRAWINGS This invention consists in the construction, arrangements and combination of the various parts of the device, whereby the objects contemplated are attained as hereinafter more fully set forth, specifically pointed out in the claims, and illustrated in the accompanying drawings, in which:
FIG. 1 is a side view of the receptacle:
FIG. 2 is a side view of the receptacle having a test tube mounted therein:
FIG. 3 is a sectional view as seen on lines 3 3 of FIG. 2; and
FIG. 4 is a side elevational view of a centrifuge which is employed with the receptacle of FIGS. 1 3.
DESCRIPTION OF THE PREFERRED EMBODIMENT In FIG. 4, the numeral 10 refers generally to a conventional centrifuge having a motor 12 positioned in the base 14. Drive shaft 16 extends upwardly from the to outer wall 24 at the upper ends thereof. Space 28 is filled with a re-freezable liquid or semi-solid substance generally referred to by the reference numeral 30.
The numeral 32 refers to a test tube or the like which may be inserted into the interior of the receptacle 22 through the open end 34. As seen in FIG. 2, the lip 36 of the test tube 32 engages the tapered upper portion of the inner wall 26. As seen in the drawings, the wall 38 of the test tube is in close proximity to the inner wall 26. v
The normal method of operation is as follows. The receptacle 22 is placed in a freezer or the like to freeze or chill the material 30 in the space 28. When the material 30 in the space 28 is at the proper temperature. the test tube 32 may be filled with the blood sample and placed in the receptacle as illustrated in FIG. 2. The receptacle and the test tube would then be placed in the metal cup-like support member 20. The cover of the centrifuge would be closed and the motor 12 energized to centrifuge the blood sample for the proper period of time. It is quite important to note that the wall 38 of the test tube 32 is maintained in close proximity to the inner wall 26 so that the frozen or chilled material 30 will reduce the ambient temperature of the blood sample.
It can be seen that the method and means described herein eliminates the need for providing a refrigerated centrifuge and also it eliminates the need for maintaining the centrifuge in an environment having a substantially reduced temperature. While the apparatus has been described as being particularly well-adapted for centrifuging chilled blood samples, it should be noted that the apparatus could be used to chill any types of test specimens requiring reduced temperatures during the centrifuging thereof. Thus it can be seen that the method and means accomplishes at least all of the stated objectives.
I claim:
1. In combination,
a centrifuge device having at least one supporting means secured to a rotating member and being adapted to support a receptacle during rotation of said supporting means,
a receptacle holder element on said supporting means, said holder element comprising inner and outer walls having a space therebetween,
a refrigerant material in said space between said wall members,
said refrigerant material and said holder element adapted to be chilled,
and a receptacle in said holder element containing a test specimen of liquid to be centrifuged, the walls of said receptaclebeing in close proximity to the inner wall of said holder element so as to'permit the refrigerant material to reduce the ambient temperature of said test specimen.
2. The combination of claim 1 wherein said inner outer walls are sealed at their upper ends.
3. The combination of claim 2 wherein said inner wall has a tapered portion at its upper end for supporting said receptacle.
4. The method of centrifuging a liquid specimen in a cold environment, comprising,
takinga receptacle having a'double wall configuration with a space therebetween,
filling said space with a liquid,
freezing said liquid,
and
bient temperature.
5. The method of claim 4 wherein said container is maintained in close proximity to the inner wall of said receptacle during said rotation.

Claims (4)

1. In combination, a centrifuge device having at least one supporting means secured to a rotating member and being adapted to support a receptacle during rotation of said supporting means, a receptacle holder element on said supporting means, said holder element comprising inner and outer walls having a space therebetween, a refrigerant material in said space between said wall members, said refrigerant material and said holder element adapted to be chilled, and a receptacle in said holder element containing a test specimen of liquid to be centrifuged, the walls of said receptacle being in close proximity to the inner wall of said holder element so as to permit the refrigerant material to reduce the ambient temperature of said test specimen.
2. The combination of claim 1 wherein said inner and outer walls are sealed at their upper ends.
3. The combination of claim 2 wherein said inner wall has a tapered portion at its upper end for supporting said receptacle.
4. The method of centrifuging a liquid specimen in a cold environment, comprising, taking a receptacle having a double wall configuration with a space therebetween, filling said space with a liquid, freezing said liquid, placing the test liquid specimen in a container, placing said container in said receptacle, and subjecting said receptacle to rotational motion and maintaining said container in close proximity to the walls of said receptacle so that the temperature of said test liquid will be reduced from its ambient temperature. 5. The method of claim 4 wherein said container is maintained in close proximity to the inner wall of said receptacle during said rotation.
US00364954A 1973-05-29 1973-05-29 Method and means for centrifuging chilled blood samples Expired - Lifetime US3851817A (en)

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD254325S (en) 1977-04-22 1980-02-26 Dick Blick Company Housing for centrifugal casting machine
US4360149A (en) * 1980-11-10 1982-11-23 Hein Jr George N Centrifuge rotor with liquid supported swinging tubes
US4557717A (en) * 1982-09-20 1985-12-10 American National Red Cross Cup insert for balancing
US4778442A (en) * 1982-06-09 1988-10-18 Shandon Southern Products Limited Centrifugation
US5707331A (en) * 1995-05-05 1998-01-13 John R. Wells Automatic multiple-decanting centrifuge
US6398972B1 (en) 1999-04-12 2002-06-04 Harvest Technologies Corporation Method for producing platelet rich plasma and/or platelet concentrate
US20020156439A1 (en) * 1997-09-12 2002-10-24 Michael J. Iskra Collection container assembly
US6612997B1 (en) * 1997-09-12 2003-09-02 Becton, Dickinson And Company Collection container assembly
US6623959B2 (en) 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
USRE38730E1 (en) * 1995-05-05 2005-04-26 Harvest Technologies Corporation Automatic multiple-decanting centrifuge and method of treating physiological fluids
US20060094865A1 (en) * 2004-10-29 2006-05-04 Kapur Terri A Intraoperative method for isolating and concentrating autologous growth factors and for forming residual autologous growth factor compositions
US20080207211A1 (en) * 2004-09-15 2008-08-28 Samsung Electronics Co., Ltd. Method and apparatus for indicating preferred layer information in multimedia broadcast/multicast service (MBMS)
WO2023124689A1 (en) * 2021-12-28 2023-07-06 海南有九医疗器械有限公司 Angle rotor low-temperature sleeve

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2351708A (en) * 1941-10-31 1944-06-20 George A Rubissow Centrifuge
US2526165A (en) * 1947-06-21 1950-10-17 Smith Eula Lee Cooling receptacle
US2876949A (en) * 1944-09-12 1959-03-10 Skarstrom Charles Centrifugal separators
US3246688A (en) * 1962-06-28 1966-04-19 Beckman Instruments Inc Controlled temperature apparatus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2351708A (en) * 1941-10-31 1944-06-20 George A Rubissow Centrifuge
US2876949A (en) * 1944-09-12 1959-03-10 Skarstrom Charles Centrifugal separators
US2526165A (en) * 1947-06-21 1950-10-17 Smith Eula Lee Cooling receptacle
US3246688A (en) * 1962-06-28 1966-04-19 Beckman Instruments Inc Controlled temperature apparatus

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD254325S (en) 1977-04-22 1980-02-26 Dick Blick Company Housing for centrifugal casting machine
US4360149A (en) * 1980-11-10 1982-11-23 Hein Jr George N Centrifuge rotor with liquid supported swinging tubes
US4778442A (en) * 1982-06-09 1988-10-18 Shandon Southern Products Limited Centrifugation
US4557717A (en) * 1982-09-20 1985-12-10 American National Red Cross Cup insert for balancing
USRE38730E1 (en) * 1995-05-05 2005-04-26 Harvest Technologies Corporation Automatic multiple-decanting centrifuge and method of treating physiological fluids
US5707331A (en) * 1995-05-05 1998-01-13 John R. Wells Automatic multiple-decanting centrifuge
US5895346A (en) * 1995-05-05 1999-04-20 Wells; John R. Automatic multiple-decanting centrifuge
USRE38757E1 (en) * 1995-05-05 2005-07-12 Harvest Technologies Corporation Automatic multiple-decanting centrifuge and container therefor
US20020156439A1 (en) * 1997-09-12 2002-10-24 Michael J. Iskra Collection container assembly
US6612997B1 (en) * 1997-09-12 2003-09-02 Becton, Dickinson And Company Collection container assembly
US6398972B1 (en) 1999-04-12 2002-06-04 Harvest Technologies Corporation Method for producing platelet rich plasma and/or platelet concentrate
US6623959B2 (en) 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
US20080207211A1 (en) * 2004-09-15 2008-08-28 Samsung Electronics Co., Ltd. Method and apparatus for indicating preferred layer information in multimedia broadcast/multicast service (MBMS)
US20060094865A1 (en) * 2004-10-29 2006-05-04 Kapur Terri A Intraoperative method for isolating and concentrating autologous growth factors and for forming residual autologous growth factor compositions
WO2023124689A1 (en) * 2021-12-28 2023-07-06 海南有九医疗器械有限公司 Angle rotor low-temperature sleeve

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