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Packaged syringe construction

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US3820652A
US3820652A US30644972A US3820652A US 3820652 A US3820652 A US 3820652A US 30644972 A US30644972 A US 30644972A US 3820652 A US3820652 A US 3820652A
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end
cylinder
shield
sheath
syringe
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T Thackston
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T Thackston
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • A61M2005/247Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/3278Apparatus for destroying used needles or syringes
    • A61M2005/3279Breaking syringe nozzles or needle hubs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile

Abstract

A cylinder for containing medicine having one end closed and a piston in the other end, a needle mounted on the closed cylinder end in a storage position exteriorly of the cylinder and shiftable to a used position impaled through the closed cylinder end, an open ended outer protector or shield about the cylinder having an internal shoulder adjacent to the closed cylinder end and an end closure on the end adjacent to the piston, and a needle sheath extending into the shield past the shoulder where it is provided with a retaining enlargement, so that the cylinder and needle are completely enclosed.

Description

United States Patent [191 Thackston 11] 3,820,652 [451 June 28, 1974 I PACKAGED SYRINGE CONSTRUCTION [76] Inventor: Thomas Thackston, 2 Esterbrook Ln., Moorestown, NJ. 08034 [22] Filed: Nov. 14, 1972 (Under Rule 47) [21] App], No.: 306,449

[52] U.S. Cl. 206/365, 128/218 NV, 128/221 [51] Int. Cl A6lm 5/00 [58] Field of Search 206/43, 17.5, 16.5, 63.2 R;

128/218 D, 218 NV, 218 P, 218 N, 218 R,

[56] References Cited UNITED STATES PATENTS 1,614,807 l/l927 Stewart 206/165 3,008,570 11/1961 Roehr et al. 206/43 FOREIGN PATENTS OR APPLICATIONS 867,972 5/1961 Great Britain 1. 128/218 NV Primary Examiner-Wil1iam T. Dixson, Jr.

[5 7] ABSTRACT A cylinder for containing medicine having one end closed and a piston in the other end, a needle mounted on the closed cylinder end in a storage position exteriorly of the cylinder and shiftable to a used position impaled through the closed cylinder end, an open ended outer protector or shield about the cylinder having an internal shoulder adjacent to the closed cylinder end and an end closure on the end adjacent to the piston, and a needle sheath extending into the shield past the shoulder where it is provided with a re taining enlargement, so that the cylinder and needle are completely enclosed.

11 Claims, 13 Drawing Figures PATENTEDmza x914 sum 1 Bf 3 mimimuuza m4 l 3820.652 sum 3 or 3 =Fl.G., l2

1 PACKAGED SYRINGE CONSTRUCTION BACKGROUND OF THE INVENTION As is well known to those versed in the medical field, the accurate control of medicines, particularly drugs, presents considerable difficulty. For example, the filling of conventional syringes by a hospital pharmacist for transport to the patient continues to result in substantial diversion of drugs out of their intended paths,

and frequent substitution of materials, such as approximately colored water, in the syringe, together with loss of sterility and great potential for serious contamination.

Of course, many other forms of tampering, loss of sterility, and other problems exist.

SUMMARY OF THE INVENTION It is, therefore, an important object of the present invention to provide a syringe to the administering technician which is reliably sterile, prefilled for assurance of contents, completely disposable, highly tamper resistant, being compact in space requirements, and entirely complete in its individual package up to the moment its contents are to be administered.

It is a more particular object of the present invention to provide a prefilled, packaged syringe having the advantageous characteristics mentioned in the preceding paragraph, which is entirely enclosed to preserve the sterility and sealed against surreptitious opening and reclosure, whilethe syringe is effectively protected in the package against damage or leakage of the contents, and further is capable of quick and easy destruction for effective disposal without possibility of unauthorized reuse.

Other objects of the present invention will become apparent upon reading the following specification and referring to the accompanying drawings, which form a material part of this disclosure.

The invention accordingly consists in the features of construction, combinations of elements, and arrangements of parts, which will be exemplified in the construction hereinafter described, and of which the scope will be indicated by the appended. claims.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a longitudinal elevational view showing a syringe package constructed in accordance with the teachings of the present invention.

FIG. 2 is a longitudinal sectional view taken generally along the line 2-2 of FIG. 1.

FIG. 3 is a transverse sectional view taken generally along the line 3-3 of FIG. 2.

FIG. 4 is a transverse sectional view taken generally along the line 4-4 of FIG. 2.

FIG. 5 is a longitudinal view illustratingan initialstep in the procedure of use, being that of removing an end closure from thepackage.

FIG. 6 is a longitudinal elevational view similar to FIG. 5, showing a slightly later step in use of the instant device, wherein a hollow pistonrod is removed from the opposite end of the packagezand affixed to the piston.

FIG. 7 is a longitudinal elevational view of the instant device showing a slightly later. step in use, wherein a protective shield or quard of the package is removed from the syringe cylinder or cartridge.

FIG. 8 is another longitudinal elevational view showing the piston rod being assembled with the piston.

FIG. 9 is another longitudinal elevational view showing the needle sheath as employed to impale the needle into the contents of the syringe.

FIG. 10 is a partial sectional view taken generally along the line 10-10 of FIG. 9, illustrating the opera tion of the impaling step in greater detail.

FIG. 11 is a longitudinal elevational view showing a final step, removal of the needle sheath, preparatory to administering of the medicien to a patient.

FIG. 12 is a partial longitudinal sectional view showing a syringe of the present invention after use and illustrating one mode of needle destruction.

FIG. 13 is a longitudinal view, partly in section, illustrating a syringe of the present invention and showing another mode of destruction rendering the syringe useless.

DESCRIPTION OF THE PREFERRED EMBODIMENT Referring now more particularly to the drawings, and specifically to FIGS. 1 and 2 thereof, a packaged sy' ringe is shown therein and generally designated 20. As best seenin FIG. 2, the syringe, there generally designated 21, is disposed entirely within the interior of the package, and includes an elongate cylinder or cartridge 22 which may conventionally be glass or other suitable material. The cylinder or cartridge 22 has one end open, as at 23, there being provided externally with ah annular circumferential flange 24. Inserted into the open end 23 of the cylinder 22 is a piston 25, which may be of rubber or other suitable material, and formedinits outer end with internal screw threads, as at 26, for interfitting formation with complementary external screw threads, as will appear presently.

The other end of the cylinder or cartridge 22, remote from the plugor piston 25, is closed, as by a centrally open fitting 28 spun or swaged about the adjacent end portion of the cylinder 22 and retaining a seal 29 in sealing relation with the adjacent cylinder end. The fitting 28 may include an open ended tubular portion 30, of relatively small diameter in alignment with an end opening 31 of the cylinder 22, and a relatively large diameter portion 32 engaged about the adjacent end re gion 33 of the cylinder, and having its edge portion 34 spun cr mmed into an external groove 35 of the cylinder. This construction effects firm sealing of the inner end of cylinder 22 bythe frangible or pierceable sealing plug 29.

The fitting 28 may advantageously be fabricated of aluminum or other suitable material, and may further be formed with annular grooves or lines of weakening, asat 36 and 37 located interiorly and exteriorly at the juncture of tubular portion 30 and enlargement 32. The scores or weakened portions 36 and 37 permit of easy breakage for irreparable destruction after use.

. Aneedle mountor carrier 40 is slidably circumposed I about the tubular portion30 of the cylinder end member 28, being generally tubular and havingits inner end provided with an annular enlargement or collar 41 28 terminating short of the closure element or seal 29, and extends backwardly or rightwardly considerably beyond the carrier. As will appear more fully hereinafter, the needle carrier 40 is shiftable inwardly or leftward to cause the inner end of the needle to pierce the seal 29 and establish communication through the needle between the interior and exterior of the cylinder 22, as for discharging the contents 45 of the cylinder.

The cylinder or cartridge 22 may be fabricated of glass, if desired. However, should the contents 45 require protection during storage from light, the glass of the cylinder 22 need not be special light shielding glass. as the package serves to completely enclose the cylinder, as by plastic components or other suitable light shielding means.

Conformably surrounding and entirely receiving the cartridge 22 is a generally cylindrical shield or enclosure 47 including a medical portion 48 conformably and spacedly surrounding the cylinder 22. The medial shield portion 48 is formed internally with a plurality of circumferentially spaced, longitudinally extending ribs. holders or spacers 49, see FIG. 4, which engage with and support the cylinder 22 in concentrically spaced relation within the shield portion 48. One end portion of the shield 47, the rightward end portion at 50 in FIG. 2, is reduced and joined to the medial portion 48 by an annular shoulder 51 surrounding the needle mount 40 spaced from the enlarged region 32 of the cylinder and piece 28.

The opposite, leftward end of the shield 47 is enlarged, as at 52, being joined to the medial portion by a tapering connecting portion 53. A closure member or cap 55 is engaged in closing relation with respect to the enlarged shield end portion 52, including a circular flat end portion 56 and a circumferential skirt 57 circumposed about the end portion 52. A pair of spaced, internal projections or wings 58 are provided on the interior of the closure cap end wall 56 for engagement with the end flange 24 of the cylinder 22, to maintain the cylinder properly positioned within the shield 47. Further, a frangible, tamper indicating seal 60, such as a thermoweld, positively retained the closure member 55 in its closed relation with respect to the end portion 52 of shield 47. That is, while the seal or securement means 60 permits manual detachment or removal of the cap 55 from the shield, such removal cannot, without the use of very special tools, be concealed. The closure member or cap 55 is further formed interiorly thereof with a central or generally coaxial, generally tubular projection or boss 59 extending into the open end 23 of the cylinder 22 into end abutting engagement with the plug or piston to limit outward movement of the latter, will appear more fully hereinafter.

A needle guard or sheath is generally designated 61, including an elongate tubular body 62 having one end closed, as at 63 outward of the free end of needle 43, and having its other, inner end open. The inner end region of the sheath body 62 is closely circumposed about the needle carrier 40 and provided with an external enlargement enalrgement or flange 64 interposed between the shield shoulder 51 and the needle carrier enlargement 41. Further, the sheath enlargement 64 is formed with a circumferential inwardly extending skirt 65 which may surround the enlarged portion 32 of the cylinder end piece 28, terminating at an eand edge 66, which is of sufficient thickness so as to be incapable of passing between the medial shield portion 40 and cylinder 22 when the latter is within the former, as shown in FIG. 2. The skirt 65 is of a material capable of flexible distension, and the skirt may be formed with a plurality of angularly spaced slits 67 extending through the end edge 66, so as to define of the skirt a plurality of resiliently flexible fingers 68. Additionally, the sheath 61 is provided on its tubular body 62 with detent means, say in the form of an annular external bead 69, all for a purpose appearing presently.

Closely circumposed about the sheath 61 is a hollow, tubular elongate member or plunger rod 70. The plunger rod 70 has one end open for receiving therethrough the sheath 61, being formed about its open end with an external circumferential flange 71. The flange 71 is advantageously noncircular. say as best seen in FIG. 4, being formed with one or more flats 72 to resist undesired rolling of the package.

The other, outer end of the rod 70 may be closed, as by a closure 73, and provided externally with a threaded extension 74. Internally of the hollow rod 70, adjacent to the end flange 71, there may be formed an annular notch or groove 75, or other mating formation for snap reception of the detent means 69.Thus, the hollow rod 70 is detachably engaged about the sheath 61, being retained thereon by interfitting relation of the detent means 69, 75, permitting of deliberate removal of the rod, as desired.

Considering the method of use in accordance with the teachings of the present invention, it will be seen in FIG. 5 that the closure member or cap has been initially removed, as in the direction of arrow 77, from the container of shield 47, as by separation of the weld or seal 60.

The next step is shown in FIG. 6, wherein the hollow rod or tube 70 has been removed from the sheath 61, sufficient force being applied to disengage the snap retention formations 69 and 75.

The hollow rod 70 may then have its threaded end 74 threadedly engaged into the exposed cavity 26 of piston 25. Such rotary threaded interengagement of the rod 70 into the piston 25 is aided by the firm frictional engagement of the ribs 49 with the cylinder 22 maintaining the latter and its received piston 25 stationary for threaded reception of the rod 70.

The shield or outer container 70, see FIG. 7, is then easily slid longitudinally outward over the sheath 61 in the direction of arrow 79, to assume the condition shown in FIG. 8.

In FIG. 9 is illustrated the method of piercing the seal 29, which may be accomplished by merely moving the needle sheath 61 inward, in the direction of arrow 80, which is permitted by resilient expansion of the skirt by outward flexure of the fingers 68 about the cartridge or container 22. This effects impaling of the inner end of the needle 43 through the seal 29, best seen in FIG. 10.

It is then only necessary to longitudinally outwardly withdraw the sheath 61, in the direction of arrow 81 as seen in FIG. 11, and the syringe 21 is ready for use in the conventional manner.

Prior to use, as in storage and transit, the syringe 21 is effectively protected by the package 20. For example, the wings or spacers 58 of cap 55 and the skirt 65 of sheath 6] serve to maintain the glass cylinder or cartridge 22 in longitudinally spaced relation within the outer container or shield 74, while the ribs 49 serve to retain the glass cartridge in radially spaced relation within the outer container.

As noted hereinbefore, the needle 43 is positively maintained against communication with the contents 45 prior to removal of the shield of the shield or outer enclosure 47 as the skirt 65 cannot pass between the outer enclosure and glass cylinder. Thus, even with re moval of the plunger rod or tube 70 from the sheath 61, the sheath positively prevents impaling of the seal 29 without prior removal of the end closure 55 and outer enclosure 47. This impaling of the seal 29 or activation of the syringe may be effected without jeopardizing sterility of the needle by mere inward longitudinal shifting of the sheath. More particularly, activation is effected by longitudinal inward movement of the sheath shoulder 64 against the needle carrier enlargement 41, all without contacting the needle.

Additionally, the sheath may be safely employed to destroy the syringe after use, by mere replacement over the needle carrier 40, and flexure to break the end piece 28 at the weakened region 36, 37 This will effectively separate the needle 43 and its carrier 40 from the cylinder 22. This condition is shown in FIG. 13, the fitting, adaptor or end piece 28 having its longitudinally extending tubular portion 27 detached from the remainder by severance or fracture along the previously weakened annular regions 36, 37. In this way, the sy ringe is rendered entirely useless, thereby preventing unauthorized refilling, and the like.

Another mode of quick and easy destruction to render the syringe useless is shown in FIG. 7, it there being seen that the sheath 61 is flexed intermediate its ends, the flexible nature of the sheath permitting bending to the phantom position, in which condition the needle 43 is fractured or otherwise rendered useless, a broken endpiece being shown in the phantom position.

While the instant packaged syringe construction may be prefilled under sterile conditions, as in a proper pharmaceutical laboratory, it is often necessary to fill syringes in other than sterile conditions, say in a hospital pharmacy, after which sterilization must take place. Thus, it is desirable that the syringe construction be ca pable of being autoclaved subsequent to filling. Toward this end, the above-described syringe construction is admirably well suited. The previously described extension or boss 59 interiorly of the closure cap 55 abuts the piston 25 to insure proper location of the latter and prevent its displacement under the influence of heat and pressure, as in autoclaving.

From the foregoing, it is seen that a packaged syringe is provided which is extremely simple in construction, durable an entirely reliable in use, economic in manufacture and assembly, and which otherwise fully accomplishes its intended objects.

Although the present invention has been described in some detail by way of illustration and example for purposes of clarity of understanding, it is understood that certain changes and modifications may be made within the spirit of the invention.

What is claimed is:

1. A packaged syringe construction comprising a cylinder for containing medicine and having one end open and the other end sealed with a penetrable diaphragm, a piston in closing relation with the open end of said cylinder, a needle mount slidably carried on said other cylinder end, a needle carried by said needle mount for movement between a storage position entirely exteriorly of said cylinder and a use position impaled through said other cylinder end for communication between the interior and exterior of said cylinder, a protective shield circumposed about said cylinder having its opposite ends open and longitudinally shiftable on said cylinder, an internal shoulder in said shield adjacent to said other cylinder end, an end closure on said shield adjacent to said one cylinder end, a needle sheath extending endwise into said shield past said shoulder, an enlargement on said sheath inwardly of said shoulder for retention thereby, and resiliently flexible finger means extending from said sheath enlargement for limiting endwise abutting engagement with said cylinder and sized to be incapable of passing between said cylinder and the surrounding shield, whereby sheath movement inwardly is limited by said finger means engagement when said shield is on the cylinder to protect the sterile integrity and activation of the device before use.

2. A packaged syringe construction according to claim 1, in combination with an elongate hollow rod removably engaged over said sheath, and interfitting fastener elements on said piston and rod for connection therebetween, whereby said rod is actuable to shift said piston into said cylinder.

3. A packaged syringe construction according to claim 2, in combination with interfitting snap formations on said rod and sheath removably retaining the former on the latter.

4. A packaged syringe construction according to claim 1, in combination with a frangible seal retaining said end closure on said shield, for positive indication of tampering.

5 A packaged syringe construction according to claim 1, said sheath being engageable with said needle mount on inward sheath movement to effect said impaling, and said finger means being flexible radially outwardly in the absence of said shield for inward sheath movement.

6. A packaged syringe construction according to claim 1, said shield shoulder retaining said shield against withdrawal toward said one cylinder end, and said end closure retaining said shield against withdrawal toward said other cylinder end.

7. A packaged syringe construction according to claim 1, said finger means being arranged about and defining a resiliently distensible skirt on said sheath enlargement and abuttingly engageable with said cylinder to limit sheath movement and expansile for additional sheath movement to shift said needle to its use position, said skirt being closely circumposed by said shield to prevent expansion of said skirt without prior removal of said shield.

8. A packaged syringe construction according to claim 1, said sheath being of flexible material permit ting of flexure to break an enclosed needle and render the syringe useless.

9. A packaged syringe construction according to claim 1, in combination with a tubular end fitting affixed to said other cylinder end and carrying said needle mount, said end fitting being formed with a circumferential weakening adapted to be deliberately severed to destroy said syringe and render it useless.

10. A packaged syringe construction according to claim 1, in combination with a retaining extension on said closure in abutting engagement with said piston to limit outward movement of the latter during autoclaw shield engaging said cylinder to retain the latter in posiingt tion during inter-fitting of said rod and piston fastener 11. A packaged syringe construction according to elements.

claim 1, in combination with frictional means on said

Claims (11)

1. A packaged syringe construction comprising a cylinder for containing medicine and having one end open and the other end sealed with a penetrable diaphragm, a piston in closing relation with the open end of said cylinder, a needle mount slidably carried on said other cylinder end, a needle carried by said needle mount for movement between a storage position entirely exteriorly of said cylinder and a use position impaled through said other cylinder end for communication between the interior and exterior of said cylinder, a protective shield circumposed about said cylinder having its opposite ends open and longitudinally shiftable on said cylinder, an internal shoulder in said shield adjacent to said other cylinder end, an end closure on said shield adjacent to said one cylinder end, a needle sheath extending endwise into said shield past said shoulder, an enlargement on said sheath inwardly of said shoulder for retention thereby, and resiliently flexible finger means extending from said sheath enlargement for limiting endwise abutting engagement with said cylinder and sized to be incapable of passing between said cylinder and the surrounding shield, whereby sheath movement inwardly is limited by said finger means engagement when said shield is on the cylinder to protect the sterile integrity and activation of the device before use.
2. A packaged syringe construction according to claim 1, in combination with an elongate hollow rod removably engaged over said sheath, and interfitting fastener elements on said piston and rod for connection therebetween, whereby said rod is actuable to shift said piston into said cylinder.
3. A packaged syringe construction according to claim 2, in combination with interfitting snap formations on said rod and sheath removably retaining the former on the latter.
4. A packaged syringe construction according to claim 1, in combination with a frangible seal retaining said end closure on said shield, for positive indication of tampering.
5. A packaged syringe construction according to claim 1, said sheath being engageable with said needle mount on inward sheath movement to effect said impaling, and said finger means being flexible radially outwardly in the absence of said shield for inward sheath movement.
6. A packaged syringe construction according to claim 1, said shield shoulder retaining said shield against withdrawal toward said one cylinder end, and said end closure retaining said shield against withdrawal towaRd said other cylinder end.
7. A packaged syringe construction according to claim 1, said finger means being arranged about and defining a resiliently distensible skirt on said sheath enlargement and abuttingly engageable with said cylinder to limit sheath movement and expansile for additional sheath movement to shift said needle to its use position, said skirt being closely circumposed by said shield to prevent expansion of said skirt without prior removal of said shield.
8. A packaged syringe construction according to claim 1, said sheath being of flexible material permitting of flexure to break an enclosed needle and render the syringe useless.
9. A packaged syringe construction according to claim 1, in combination with a tubular end fitting affixed to said other cylinder end and carrying said needle mount, said end fitting being formed with a circumferential weakening adapted to be deliberately severed to destroy said syringe and render it useless.
10. A packaged syringe construction according to claim 1, in combination with a retaining extension on said closure in abutting engagement with said piston to limit outward movement of the latter during autoclaving.
11. A packaged syringe construction according to claim 1, in combination with frictional means on said shield engaging said cylinder to retain the latter in position during interfitting of said rod and piston fastener elements.
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Cited By (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3916893A (en) * 1973-03-28 1975-11-04 Hoechst Ag Single-injection device
US3930499A (en) * 1972-11-22 1976-01-06 Laboratoire S P A D Hypodermic syringe with parts disposable after use
US3943926A (en) * 1974-04-10 1976-03-16 Oscar Arvizu Barragan Wholly disposable dental type syringe
US4026287A (en) * 1975-12-10 1977-05-31 Irene Haller Syringe with retractable cannula
US4148316A (en) * 1977-08-29 1979-04-10 Stewart-Naumann Laboratories, Inc. Self-sealed hypodermic syringe
US4178930A (en) * 1977-10-31 1979-12-18 Fisher Frank R Jr Combined cap and needle structure
US4413992A (en) * 1981-12-02 1983-11-08 Baxter Travenol Laboratories, Inc. Cannula support assembly and its method of manufacture
US4496352A (en) * 1981-12-02 1985-01-29 Baxter Travenol Laboratories, Inc. Cannula support assembly and its method of manufacture
WO1985003006A1 (en) * 1984-01-12 1985-07-18 Walton Ii Sumner Syringe needle sheath and shield
GB2162428A (en) * 1984-01-12 1986-02-05 Walton Sumner Syringe needle sheath and shield
US4574456A (en) * 1981-12-02 1986-03-11 Baxter Travenol Laboratories, Inc. Method of manufacturing a support assembly
US4742910A (en) * 1987-06-22 1988-05-10 Staebler Charles R Needle sheath holder
US4804366A (en) * 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
WO1989002760A1 (en) * 1987-09-25 1989-04-06 Habley Medical Technology Corporation Disposable, pre-sterilizable syringe for a pre-filled medication cartridge
WO1989003703A1 (en) * 1987-10-29 1989-05-05 Baxter International Inc. Drug delivery cartridge with protective cover
WO1989004680A1 (en) * 1987-11-17 1989-06-01 Seldoren Limited A detachable housing for a syringe
WO1991001152A1 (en) * 1989-07-18 1991-02-07 Tri/West Systems, Inc. Syringe plunger rod mount
US5007901A (en) * 1989-11-24 1991-04-16 Shields Jack W Intravenous catheter insertion device
US5059179A (en) * 1989-05-15 1991-10-22 David Quatrochi Non-reusable syringe assembly
WO1992006725A1 (en) * 1990-10-12 1992-04-30 Habley Medical Technology Corporation Disposal module with sleeve for prefilled cartridges
US5135496A (en) * 1989-05-17 1992-08-04 Arzneimittel Gmbh Apotheker Vetter & Co. Tamper-proof hypodermic syringe assembly
WO1993002728A1 (en) * 1991-08-07 1993-02-18 Sterling Winthrop Inc. Safety syringe assembly for pre-filled medication cartridges
US5324272A (en) * 1990-07-27 1994-06-28 Sterling Winthrop Inc. Multiple-celled safety package, needle guard and safe disposal module for prefilled medication cartridge
US5372590A (en) * 1990-07-27 1994-12-13 Habley Medical Technology Corporation Multi-celled safety package, needle guard and safety disposal module with sleeve for prefilled medication cartridges
US5403288A (en) * 1992-02-13 1995-04-04 Stanners; Sydney D. Safety sleeve for dental syringe
US5558649A (en) * 1995-01-25 1996-09-24 Shields; Jack W. Conical syringe/needle shield
WO1996030065A1 (en) * 1995-03-24 1996-10-03 Owen Mumford Limited Improvements relating to medical injection devices
US5593391A (en) * 1992-02-13 1997-01-14 Stanners; Sydney D. Ampule safety syringe
US5681291A (en) * 1992-11-19 1997-10-28 Tebro S.A. Disposable auto-injector for prefilled syringes
US5693027A (en) * 1990-09-21 1997-12-02 Novo Nordisk A/S Adaptor top
US5788677A (en) * 1995-08-22 1998-08-04 Botich; Michael J. Pre-filled retractable needle injection ampoules
WO2000007646A1 (en) * 1998-08-06 2000-02-17 Schott Pharmaceutical Packaging, Inc. Protective syringe sheath
US20030078195A1 (en) * 2001-08-27 2003-04-24 Kristensen Lars Thougaard Cartridge and medical delivery system accommodating such cartridge
US20040111063A1 (en) * 1995-08-22 2004-06-10 Botich Michael J. Pre-filled retractable needle injection ampoules
US20040167476A1 (en) * 2003-02-24 2004-08-26 Westbye Lars Tommy Tamper evident needle guard for syringes
US20080082055A1 (en) * 2006-09-29 2008-04-03 Tyco Healthcare Group Lp Detachable plunger rod syringe
US20080183140A1 (en) * 2006-11-29 2008-07-31 West Pharmaceutical Services, Inc. Syringe cartridge system
US20090259197A1 (en) * 2006-07-15 2009-10-15 Novo Nordisk A/S Medical Delivery System with Flexible Blocking Element
US20090281505A1 (en) * 2006-07-15 2009-11-12 Novo Nordisk A/S Medical Delivery System with Asymmetrical Coding Means
US20100010472A1 (en) * 2004-12-24 2010-01-14 Ian Marshall Moore Safety syringe
US20100010455A1 (en) * 2006-08-28 2010-01-14 Novo Nordisk A/S Medical Delivery System Adapted to be Locked Axially and Unlocked Rotationally
US20100042054A1 (en) * 2006-11-17 2010-02-18 Novo Nordisk A/S Medical Delivery System Comprising a Coding Mechanism Between Dosing Assembly and Medicament Container
US20100106099A1 (en) * 2006-12-21 2010-04-29 Novo Nordisk A/S Syringe Device
US20100324498A1 (en) * 2006-12-15 2010-12-23 Novo Nordisk A/S Medical delivery system comprising a container and a dosing assembly with radially moving fastening means
US20110046561A1 (en) * 2008-02-07 2011-02-24 Brigitte Pickhard Injection syringe
US20110046566A1 (en) * 2006-11-21 2011-02-24 Novo Nordisk A/S Medical Delivery System Comprising Locking Ring with L-Shaped Grooves
US20130256166A1 (en) * 2010-12-14 2013-10-03 Becton Dickinson France Compact injection device
WO2013176703A1 (en) * 2012-05-21 2013-11-28 Baxter International, Inc. Syringe storage tray
US8632506B2 (en) 2006-06-30 2014-01-21 Novo Nordisk A/S Medical delivery system comprising a coding mechanism
US20140364813A1 (en) * 2004-12-08 2014-12-11 Roche Diagnostics International Ag Adapter for injection appliance
EP2944340A1 (en) * 2014-05-12 2015-11-18 Sanofi Activating mechanism for a medicament delivery device and medicament delivery device
EP2944341A1 (en) * 2014-05-12 2015-11-18 Sanofi Activating mechanism for a medicament delivery device and medicament delivery device
US20160136637A1 (en) * 2013-06-13 2016-05-19 Hamilton Bonaduz Ag Syringe having a mechanical coupling piece
WO2017076925A1 (en) * 2015-11-05 2017-05-11 Sanofi-Aventis Deutschland Gmbh Cartridge carrier assembly
EP3173114A1 (en) * 2015-11-26 2017-05-31 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Device for producing a tight connection between a needle and a container
US9682196B1 (en) 2012-01-09 2017-06-20 Verena Solutions LLC Protective cover for a syringe needle

Cited By (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3930499A (en) * 1972-11-22 1976-01-06 Laboratoire S P A D Hypodermic syringe with parts disposable after use
US3916893A (en) * 1973-03-28 1975-11-04 Hoechst Ag Single-injection device
US3943926A (en) * 1974-04-10 1976-03-16 Oscar Arvizu Barragan Wholly disposable dental type syringe
US4026287A (en) * 1975-12-10 1977-05-31 Irene Haller Syringe with retractable cannula
US4148316A (en) * 1977-08-29 1979-04-10 Stewart-Naumann Laboratories, Inc. Self-sealed hypodermic syringe
US4178930A (en) * 1977-10-31 1979-12-18 Fisher Frank R Jr Combined cap and needle structure
US4413992A (en) * 1981-12-02 1983-11-08 Baxter Travenol Laboratories, Inc. Cannula support assembly and its method of manufacture
US4496352A (en) * 1981-12-02 1985-01-29 Baxter Travenol Laboratories, Inc. Cannula support assembly and its method of manufacture
US4574456A (en) * 1981-12-02 1986-03-11 Baxter Travenol Laboratories, Inc. Method of manufacturing a support assembly
GB2162428A (en) * 1984-01-12 1986-02-05 Walton Sumner Syringe needle sheath and shield
WO1985003006A1 (en) * 1984-01-12 1985-07-18 Walton Ii Sumner Syringe needle sheath and shield
US4742910A (en) * 1987-06-22 1988-05-10 Staebler Charles R Needle sheath holder
EP0333853A1 (en) * 1987-09-25 1989-09-27 Habley Medical Technology Corporation Disposable, pre-sterilizable syringe for a pre-filled medication cartridge
WO1989002760A1 (en) * 1987-09-25 1989-04-06 Habley Medical Technology Corporation Disposable, pre-sterilizable syringe for a pre-filled medication cartridge
US4834717A (en) * 1987-09-25 1989-05-30 Habley Medical Technology Corporation Disposable, pre-sterilizable syringe for a pre-filled medication cartridge
WO1989004190A1 (en) * 1987-10-29 1989-05-18 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
WO1989003703A1 (en) * 1987-10-29 1989-05-05 Baxter International Inc. Drug delivery cartridge with protective cover
US4850978A (en) * 1987-10-29 1989-07-25 Baxter International Inc. Drug delivery cartridge with protective cover
US4804366A (en) * 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
WO1989004680A1 (en) * 1987-11-17 1989-06-01 Seldoren Limited A detachable housing for a syringe
GB2230193A (en) * 1987-11-17 1990-10-17 Seldoren Ltd A detachable housing for a syringe
GB2230193B (en) * 1987-11-17 1991-07-03 Seldoren Ltd A detachable housing for a syringe
US5059179A (en) * 1989-05-15 1991-10-22 David Quatrochi Non-reusable syringe assembly
US5135496A (en) * 1989-05-17 1992-08-04 Arzneimittel Gmbh Apotheker Vetter & Co. Tamper-proof hypodermic syringe assembly
US5067947A (en) * 1989-07-18 1991-11-26 Tri/West Systems, Inc. Syringe plunger rod mount
WO1991001152A1 (en) * 1989-07-18 1991-02-07 Tri/West Systems, Inc. Syringe plunger rod mount
US5007901A (en) * 1989-11-24 1991-04-16 Shields Jack W Intravenous catheter insertion device
US5372590A (en) * 1990-07-27 1994-12-13 Habley Medical Technology Corporation Multi-celled safety package, needle guard and safety disposal module with sleeve for prefilled medication cartridges
US5380296A (en) * 1990-07-27 1995-01-10 Sterling Winthrop Inc. Multi-celled safety package, needle guard and safe disposal module for pre-filled medication cartridges
US5324272A (en) * 1990-07-27 1994-06-28 Sterling Winthrop Inc. Multiple-celled safety package, needle guard and safe disposal module for prefilled medication cartridge
US5693027A (en) * 1990-09-21 1997-12-02 Novo Nordisk A/S Adaptor top
WO1992006725A1 (en) * 1990-10-12 1992-04-30 Habley Medical Technology Corporation Disposal module with sleeve for prefilled cartridges
WO1993002728A1 (en) * 1991-08-07 1993-02-18 Sterling Winthrop Inc. Safety syringe assembly for pre-filled medication cartridges
US5403288A (en) * 1992-02-13 1995-04-04 Stanners; Sydney D. Safety sleeve for dental syringe
US5593391A (en) * 1992-02-13 1997-01-14 Stanners; Sydney D. Ampule safety syringe
US5681291A (en) * 1992-11-19 1997-10-28 Tebro S.A. Disposable auto-injector for prefilled syringes
US5558649A (en) * 1995-01-25 1996-09-24 Shields; Jack W. Conical syringe/needle shield
WO1996030065A1 (en) * 1995-03-24 1996-10-03 Owen Mumford Limited Improvements relating to medical injection devices
US5928205A (en) * 1995-03-24 1999-07-27 Owen Mumford Limited Medical injection devices
US7300416B2 (en) 1995-08-22 2007-11-27 Specialized Health Products International Pre-filled retractable needle injection ampoules
US20040111063A1 (en) * 1995-08-22 2004-06-10 Botich Michael J. Pre-filled retractable needle injection ampoules
US5788677A (en) * 1995-08-22 1998-08-04 Botich; Michael J. Pre-filled retractable needle injection ampoules
WO2000007646A1 (en) * 1998-08-06 2000-02-17 Schott Pharmaceutical Packaging, Inc. Protective syringe sheath
US20030078195A1 (en) * 2001-08-27 2003-04-24 Kristensen Lars Thougaard Cartridge and medical delivery system accommodating such cartridge
US8177767B2 (en) 2001-08-27 2012-05-15 Novo Nordisk A/S Cartridge and medical delivery system accommodating such cartridge
US20070233008A1 (en) * 2001-08-27 2007-10-04 Novo Nordisk A/S Cartridge and medical delivery system accommodating such cartridge
US8608693B2 (en) 2003-02-24 2013-12-17 Safety Syringes, Inc. Tamper evident needle guard for syringes
US9550027B2 (en) 2003-02-24 2017-01-24 Safety Syringes, Inc. Tamper evident needle guard for syringes
US20040167476A1 (en) * 2003-02-24 2004-08-26 Westbye Lars Tommy Tamper evident needle guard for syringes
US20140364813A1 (en) * 2004-12-08 2014-12-11 Roche Diagnostics International Ag Adapter for injection appliance
US20100010472A1 (en) * 2004-12-24 2010-01-14 Ian Marshall Moore Safety syringe
US8632506B2 (en) 2006-06-30 2014-01-21 Novo Nordisk A/S Medical delivery system comprising a coding mechanism
US20090312717A1 (en) * 2006-07-15 2009-12-17 Asger Voss Christiansen Medical Delivery System with a Rotatable Coding Element
US20100030158A1 (en) * 2006-07-15 2010-02-04 Novo Nordisk A/S Medical Delivery System with Flexible Blocking Element
US20090281505A1 (en) * 2006-07-15 2009-11-12 Novo Nordisk A/S Medical Delivery System with Asymmetrical Coding Means
US9050397B2 (en) 2006-07-15 2015-06-09 Novo Nordisk A/S Medical delivery system with a rotatable coding element
US8579868B2 (en) 2006-07-15 2013-11-12 Novo Nordisk A/S Medical delivery system with flexible blocking element
US8708972B2 (en) 2006-07-15 2014-04-29 Novo Nordisk A/S Medical delivery system with a rotatable coding element
US20090259197A1 (en) * 2006-07-15 2009-10-15 Novo Nordisk A/S Medical Delivery System with Flexible Blocking Element
US8613731B2 (en) 2006-07-15 2013-12-24 Novo Nordisk A/S Medical delivery system with asymmetrical coding means
US20100010455A1 (en) * 2006-08-28 2010-01-14 Novo Nordisk A/S Medical Delivery System Adapted to be Locked Axially and Unlocked Rotationally
US8038656B2 (en) 2006-09-29 2011-10-18 Tyco Healthcare Group Lp Detachable plunger rod syringe
US20080082055A1 (en) * 2006-09-29 2008-04-03 Tyco Healthcare Group Lp Detachable plunger rod syringe
US20100042054A1 (en) * 2006-11-17 2010-02-18 Novo Nordisk A/S Medical Delivery System Comprising a Coding Mechanism Between Dosing Assembly and Medicament Container
US20110046566A1 (en) * 2006-11-21 2011-02-24 Novo Nordisk A/S Medical Delivery System Comprising Locking Ring with L-Shaped Grooves
US8672897B2 (en) 2006-11-21 2014-03-18 Novo Nordisk A/S Medical delivery system comprising locking ring with L-shaped grooves
US9289558B2 (en) 2006-11-21 2016-03-22 Novo Nordisk A/S Medical delivery system comprising locking ring with L-shaped grooves
US20080183140A1 (en) * 2006-11-29 2008-07-31 West Pharmaceutical Services, Inc. Syringe cartridge system
US20100324498A1 (en) * 2006-12-15 2010-12-23 Novo Nordisk A/S Medical delivery system comprising a container and a dosing assembly with radially moving fastening means
US8617125B2 (en) 2006-12-15 2013-12-31 Novo Nordisk A/S Medical delivery system comprising a container and a dosing assembly with radially moving fastening means
US20100106099A1 (en) * 2006-12-21 2010-04-29 Novo Nordisk A/S Syringe Device
US8740857B2 (en) 2006-12-21 2014-06-03 Novo Nordisk A/S Syringe device
US8728042B2 (en) * 2008-02-07 2014-05-20 Pharma Consult Ges.M.B.H. Injection syringe
US20110046561A1 (en) * 2008-02-07 2011-02-24 Brigitte Pickhard Injection syringe
US20130256166A1 (en) * 2010-12-14 2013-10-03 Becton Dickinson France Compact injection device
US9333146B2 (en) * 2010-12-14 2016-05-10 Becton Dickinson France S.A.S. Compact injection device
US9682196B1 (en) 2012-01-09 2017-06-20 Verena Solutions LLC Protective cover for a syringe needle
WO2013176703A1 (en) * 2012-05-21 2013-11-28 Baxter International, Inc. Syringe storage tray
US9808570B2 (en) 2012-05-21 2017-11-07 Baxalta Incorporated Syringe storage tray
US20160136637A1 (en) * 2013-06-13 2016-05-19 Hamilton Bonaduz Ag Syringe having a mechanical coupling piece
US9517463B2 (en) * 2013-06-13 2016-12-13 Hamilton Bonaduz Ag Syringe having a mechanical coupling piece
WO2015173166A1 (en) * 2014-05-12 2015-11-19 Sanofi Medicament delivery device having an activating mechanism
EP2944340A1 (en) * 2014-05-12 2015-11-18 Sanofi Activating mechanism for a medicament delivery device and medicament delivery device
WO2015173167A1 (en) * 2014-05-12 2015-11-19 Sanofi Activating mechanism for a medicament delivery device and medicament delivery device
EP2944341A1 (en) * 2014-05-12 2015-11-18 Sanofi Activating mechanism for a medicament delivery device and medicament delivery device
WO2017076925A1 (en) * 2015-11-05 2017-05-11 Sanofi-Aventis Deutschland Gmbh Cartridge carrier assembly
EP3173114A1 (en) * 2015-11-26 2017-05-31 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Device for producing a tight connection between a needle and a container
FR3044230A1 (en) * 2015-11-26 2017-06-02 Commissariat Energie Atomique An apparatus for providing hermetic connection between a needle and a container

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