New! View global litigation for patent families

US3785549A - Centrifuge chuck for disposable, snap-in centrifuge rotor - Google Patents

Centrifuge chuck for disposable, snap-in centrifuge rotor Download PDF

Info

Publication number
US3785549A
US3785549A US3785549DA US3785549A US 3785549 A US3785549 A US 3785549A US 3785549D A US3785549D A US 3785549DA US 3785549 A US3785549 A US 3785549A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
chuck
rotor
surface
lower
means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
A Latham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HAEMONETICS Corp A MASSACHUSETTS CORP
Original Assignee
Haemonetics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B7/00Elements of centrifuges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Abstract

A chuck suitable for holding a disposable centrifuge rotor during centrifuging and requiring only minimum skill to place in position. Once the rotor is snapped into position on the chuck it is held by an elastomeric gripping member. The base of the rotor is designed to effect this holding. In removing the rotor, only a manual tipping action involving a modest horizontal force near the top of the rotor is required. The chuck is simple and inexpensive; and it does not require any great deal of technical skill to operate.

Description

United States Patent [191 CENTRIFUGE CHUCK FOR DISPOSABLE,

SNAP-IN CENTRIFUGE ROTOR [75] Inventor: Allen Latham, Jr., Jamaica Plain,

Mass. [73] Assignee: l-laemonetics Corporation, Natick,

Mass. [22] Filed: July 31, 1972 [21] Appl. No.: 276,677

52 US. Cl 233/23 R [51] Int. Cl B04b 9/00 [58] Field of Search 233/2l, 23 R, 23 A, 233/24, 26," l R; 279/1 B, 1 SG, 1 Q, 24

[56] References Cited UNITED STATES PATENTS 3,581,981 6/197! Latham 233/21 IIIIIIIIII *i 4 20 Till I Latham, Jr.

[111 3,785,549 Jan. 15, 1974 610,058 8/1898 lones 233/2] Primary Examiner-George l-l. Krizmanich Att0rneyBessie A. Lepper 5 7 ABSTRACT A chuck suitable for holding a disposable centrifuge rotor during centrifuging and requiring only minimum skill to place in position. Once the rotor is snapped into position on the chuck it is held by an elastomeric gripping member. The base of the rotor is designed to effect this holding. In removing the rotor, only a man ual tipping action involving a modest horizontal force near the top of the rotor is required. The chuck is simple and inexpensive; and it does not require any great deal of technical skill to operate.

8 Claims, 5 Drawing Figures PATENTEBJAH 1 51914 SHEU 1 BF 3 PATENTEBJAN 1 5 i974 SHEEI 20F 3 PATENTEDJAN 1 51914 3. 785.549

" sum 3 0r 5 Fig. 5

This invention relates to centrifuges and more partic-' I ularly to a unique combination of a chuck and a snap-in disposable centrifuge rotor for attachment thereto.

In centrifuging liquids such as blood, there is a need for a simple chuck which can hold the centrifuge rotor in proper alignment and which provides rapid and reliable engagement and disengagement with the rotor. In processing blood, the technician who performs the processing steps should be as free as possible from engineering details. This, in turn, means that he should be able to place acentrifuge rotor in a chuck to attain automatic registry both with respect to axial alignment and perpendicular alignment and to effect the locking of the rotor in the chuck with the minimum number of simple motions.

The disposable rotor of this, invention is of an upwardly tapering, bell-shaped configuration which is not adapted for manual gripping to lift it out of a standard O-ring form of chuck. A mechanical ejection system chuck such as described in U.S. Pat. No.3,581.98l, provides a technically acceptable way of extracting the bowl from the chuck. However, for some large-scale use application, this type of chuck is too expensive.

It is therefore a primary object of this invention to provide a simple, easily usedchuck-rotor combination for use in a centrifuge. It is another objectof the invention to provide a chuck-rotor combination of the character described which is particularly usefulin centrifuges used to process blood andwhich requires only simple operations to lock or unlock the centrifuge rotor into the chuck, these operations involving only a snapping in of the rotor and in one embodiment the additional step of the tightening of three bolts. It is yet another object to provide an inexpensive chuck which is particularly usable forone-use centrifuge rotors. Other objects of the invention will in part be obvious and will in part be apparent hereinafter.

In thechuck-rotor combination of this invention, the chuck is formed of an upper clamp ring and a lower chuck body on which the rotor fits for automatic axial and perpendicular alignment. The upper clamp ring and lower chuck body are configuredto define between them a groove adapted to hold an elastomeric gripping member, and they may beformed as one integral part or as two separate components adapted to be locked together by screws. The base of the rotor is designed to provide an upwardly inclined shoulder over which the elastomeric gripping member fits in gripping engagement. In the embodiment in which the chuckis formed of two lockable components when the screws which lock the chuck members are turned about one full turn to loosen the chuck members the rotor may be snapped into place in the chuck. Once the rotor is snapped into place, the screws are tightened and the centrifuge is in operational condition. Removal of the rotor is accomplished with similar ease. In an alternative embodiment wherein the chuck is formed as a single component the rotor is installed with a firm, downward force normally applied with both hands and may be removed with the aid of a simple tool.

The invention accordingly comprises the features of construction, combination of elements, and arrange ment of parts which will be exemplified in the construc- 2 tion hereinafter set forth, and the scope of the invention will be indicated in the claims.

For a fuller understanding of the nature and objects of the invention, reference should be had to the following detailed description taken in connection with the accompanying drawings in which FIG. 1 is a vertical cross section of the chuck and rotor of an embodiment of this invention in which the chuck is formed of two separate components;

FIG. 2 is a bottom view of the chuck of FIG. 1 showing the position of the locking screws;

FIG. 3 is an enlarged detailed cross section showing the configurations of the chuck of FIG. 1, the centrifuge rotor base, the elastomeric gripping ring and a locking screw in the unlocked position;

FIG. 4 is an enlarged detailed cross section as in FIG.

3 showing the rotor and chuck in the locking position;

and

FIG. 5 is an enlarged detailed cross section of one portion of the chuck and rotor of an embodiment in which the chuck is formed as a single component and the gripping member is of a unique configuration.

In FIG. 1 the chuck and gripping member are shown in cross section and the rotor in partial crosssection. Except for the design of the external configuration of the base of the rotor which is critical to this invention, the rotor shown is similar in internal construction and operation to that described in U.S. Pat. No. 3,145,713 (see particularly FIG. 6 of that patent). For this reason, no detailed description of the internal design of the rotor is required, only the basic flow pattern being illustrated.

The rotor 10 is mounted'in chuck 11 through elastomeric gripping member 12. The chuck in the embodiment of FIG. 1 is formed of an upper clamp means formed as ring 13 anda lower chuck body 14, the latter being adapted for attachment to a rotatable spindle 15 such as the temperature-controlled spindle described in U.S. Pat. No. 3,604,769. The upper and lower chuck members are locked by at least'three locking members 16 (See also FIG. 2

The rotor 10, which may be a one-use disposable rotor, is designed to be attached through a stationary external connection 20 to a source of liquid (e.g., blood) to be centrifuged through inlet tube 21, and to a storage container for the centrifugate (e.g., blood plasma) through discharge tube 22. The stationary inlet tube 20 is in fluid communication with a stationary feed tube 23 extending. into the rotor. Rotary. seals such as described in U.S. Pat. Nos. 3,409,213 and 3,565,330 provide the necessary contamination-free sealing between the stationary-components and the rotating rotor 10. A baffle system such as that shown in FIG. 1 to be made up of baffle plates 24 and 25 direct the liquid flow and permit the centrifuged solids (e.g., blood red cells) to be collected in the centrifuge rotor.

The rotor housing is formed as a tapered bell-shaped section 30 and a bottom member 31 which is joined to the bell-shaped section to form, with a rotary seal (not shown) a fluid-tight enclosure within the housing. The bottom member is formed from its center outwardly to have a central circular alignment surface 32, an upwardly inclined surface 33 forming a major portion of the bottom member and a flat peripheral surface 34.

As will be seen in the enlarged cross sectional detail of FIG. 3, the outer lower periphery of the base of the bell-shaped section is configured to define an inclined shoulder 35 the angle of inclination Qof whichapproximates 45. that is it is 45 1 The shoulder 35 is formed between a lower wall section, consisting of a slightly inclined wall 36 and a vertical wall 37, and upper vertical wall section 38. The angle defined between wall 36 and the vertical ranges between 15 and 30 and the height of vertical wall 37, which represents the maximum diameter of the rotor base will normally be about 0.03 inch. Although wall 36 may also be vertical, a preferred construction is to provide a lead" on the rim of the base to make insertion of the bowl easier. The importance of shoulder 35 and its location will be made apparent in the discussion which follows.

Returning to FIG. 1, it will be seen that the upper surface of chuck body 14 is configured, from its center outwardly, to have a shallow central well 40 sized to correspond in diameter to the diameter of the central circular alignment surface 32 of the rotor, an upwardly inclined surface 41 corresponding to, but spaced from, the upwardly inclined surface 33 of the rotor and a flat annular surface 42 corresponding to the flat peripheral surface 34 of the rotor. The engagement of the flat peripheral surfaces 34 and 42 and of the central circular alignment surface 32 of the rotor within the shallow central well 40 automatically provides both perpendicular and axial alignment of the rotor in the chuck body. The chuck is mounted on spindle 15 through collar 43 by suitable means such as by use of an adhesive along with a close cylindrical fit.

As will be seen more clearly in FIGS. 3 and 4, the lower chuck body 14 has an outer flat peripheral surface 44 somewhat lower than the flat annular surface 42. An upwardly extending annular ring 45 joins flat annular surfaces 42 and 44. The upper surface 46 of ring 45 serves as one side of groove 47 which is adapted to contain elastomeric gripping member in the form of an O-ring 12. The inner surface 48 of ring 45 is of a diameter which permits engagement with the vertical wall 37 of the lower wall section of the rotor base with preferably about an 0.010 inch clearance. This clearance can range between about 0.008 and 0.015 inch.

Preferably the lower edge of gripping shoulder 35 of the rotor base is between about 0.1 and 0.2 inch above the perpendiculant register, i.e., annular surface 42, for a rotor which has a diameter ranging between about 4.0 and 5.5 inches in diameter measured at the vertical wall 37 of the lower section of the rotor base. Thus the ratio of rotor base edge height, as measured along the bottom edge of shoulder 35, above the perpendiculant register to the outside diameter of the rotor base may range between about 0.1/5.5 to 0.2/4.0 or about 0.02 to 0.05. Another relationship which may be used to define the configuration of the rotor base and the gripping means is the ratio of rotor base edge height (distance from surface 42 to the bottom edge of wall 37) to shoulder edge height (distance from surface 42 to the bottom edge of shoulder 35). This ratio should be between about 0.2 and 0.6.

The upper chuck clamp ring 13 will be seen in FIGS. 3 and 4 to have an internal surface which is machined to define a lower vertical wall section 51 and an upper vertical wall section 52 of small diameter. These wall sections are joined by shoulder 53. The lower vertical wall section 51 is aligned with the outer surface of ring 45 for engagement herewith. The upper portion of wall member groove 47, the depth of which is controllable to alter the cross sectional configuration of the O-ring to cause it to loosen or grip the rotor as seen in FIGS. 3 and 4, respectively.

Each of the chuck locking means 16 are conveniently formed of a clamp screw 55 which is internally threaded to engage the threads of a button-headed screw 56.

When the rotor is to be installed in the chuck the locking means are loosened by turning clamp screw 55 by about one turn to place the chuck clamp ring and chuck body in the relative positions shown in FIG. 3. The rotor is gripped manually around its top and is then thrust firmly downwardly to become engaged in the position shown in FIG. 3. It will be seen that all that is involved is the insertion of the gripping shoulder 35 under a small portion of O-ring l2. Rotor alingment in the chuck is automatically achieved. Then the locking means are tightened by turning screws 55 by about one full turn. As will be seen in FIG. 4, the downward movement of clamp ring 13 forces the O-ring to engage and tightly grip the rotor shoulder 35. The rotor is thus firmly held in the chuck when the chuck is rotated. When the chuck is stopped, the chuck clamp ring is raised by turning screws 55 and the rotor is removed by subjecting it to a tipping action.

FIG. 5 illustrates in fragmented cross section a second embodiment of the chuck and gripping means wherein the lower chuck body means and the upper chuck ring means are formed as one integral component, thus eliminating the need for any chuck locking means such as the clamp screw 55 and buttonheaded screw 56 of FIGS. 3 and 4. In FIG. 5 like reference numerals are used to refer to like components in FIGS. 3 and 4.

The chuck 11 of the apparatus of FIG. 5 is formed of a single metal piece 60 which provides the required lower chuck body 61 and upper chuck ring 62. It is, of course, within the scope of this invention to form these elements as separate components and fasten them together by some appropriate means such as screws. However, this will normally not be the preferred construction. The groove 63, wherein the elastomeric gripping ring 64 is held, is machined into the internal surface 65 of chuck ring 62. The gripping member 64 is an annular elastomeric member cut to set in groove 63 and to make a tight fit with lower vertical wall 37 and shoulder 35 of the rotor bottom. Thus the cross section of gripping member 64 may be described as rectangular with a triangular extension 66 integral with the inner top portion, the lower exposed surface 67 of the triangle being adapted to make a tight fit with shoulder 35 of the rotor base.

A comparison with gripping ring 12 of FIGS. 3 and 4, will show that the uniquely configured locking member 64 of FIG. 5 serves the identical purpose of gripping ring 12 and in the same manner. The apparatus of FIG. 5 has the advantage of the operators being able to insert and withdraw the rotor without having to screw and unscrew any locking means. Insertion of the rotor is accomplished by forcing it into locking position (FIG. 5) with a firm force applied directly downwardly. Removal of the rotor is accomplished by using the tool 70 which is in effect a rubber coated lever 71 attached to a handle 72. The lever 71 is used to apply force to centrifuge housing 30, using the internal wall of the protective housing 73, which is placed around the centrifuge, as s rigid support against which lever 71 is rested. A slight angular movement of handle 72 of the departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the accompanying drawings shall be interpreted as illustrative and not in a limiting sense.

I claim:

1. In a centrifuge in which a rotor is held for highspeed rotation in a chuck mounted on a rotatable spindle, the combination of a rotor and a chuck adapted for quick engagement with said rotor through gripping means, said chuck comprising in combination a. lower chuck body means configured on its upper surface to comprise, from its center outwardly, a

central shallow well providing an engageable wall,

an upwardly inclined surface, a first flat annular surface, and an upwardly extending wall having an internal surface and an essentially flat second annular surface;

b. upper chuck ring means providing an angled internal surface,

c. a groove defined by said second annular surface of said lower chuck body means and said angled internal surface of said upper chuck ring means; said rotor comprising d. a bottom member configured on its surface to comprise, from its center outwardly,Ia central circular alignment surface engaging said wall of said central shallow well of said chuck, an upwardly inclined surface essentially corresponding in area to said inclined surface of said lower chuck body means and spaced therefrom, and a peripheral flat annular surface engaging said first flat annular surface of said lower chuck body means, and

e. rotor housing means joined to said bottom member and forming therewith a rotor base configured from the bottom up to have an outwardly inclined section, a lower vertical gripping section representing the maximum diameter of said rotor base and just clearing said internal surface of said upwardly extending wall of said lower chuck body means, an inwardly inclined gripping shoulder and an upper vertical section; forcing f. and gripping means comprising an elastomeric gripping ring held within said groove in said chuck in combination with locking means forcing said lower v'ertical gripping section and said inwardly inclined gripping shoulder of said rotor base into engagement with said gripping ring thereby to lock said rotor to said chuck through said gripping means.

2. A centrifuge in accordance with claim 1 wherein the angle defined between said outwardly inclined section of said rotor base and saidinternal surface of said upwardly extending wall of said lower chuck body means ranges between about 15 and 30.

3. A centrifuge in accordance with claim 1 wherein the clearance between said lower vertical gripping section of said rotor base and said internal surface of said upwardly extending wall of said lower chuck body means ranges between about 0.008 and 0.015 inch.

4. A centrifuge in accordance with claim l wherein the ratio of the height of said rotor base, measured from said first flat annular surface of said lower chuck body means to the lower edge of said shoulder, to the outside diameter of said lower vertical gripping section of said rotor base ranges between about 0.02 and 0.05.

5. A centrifuge in accordance with claim 1 wherein the ratio of the height of said rotor base, measured from said first flat annular surface of said lower chuck body means to the lower edge of said lower vertical gripping section, to the height of said shoulder, measured from said first flat annular surface to the lower edge of said shoulder, ranges between about 0.2 and 0.6.

6. A centrifuge in accordance with claim 1 wherein said lower chuck body means is separate from said upper chuck ring means and includes a flat peripheral surface which surrounds said upwardly extending wall and is lower than said first flat annular surface; wherein said angled internal surface of said upper chuck ring means is defined by a lower vertical wall section, and an upper vertical wall section joined thereto through a shoulder, whereby a portion of said lower vertical wall section engages an'external surface of said upwardly extending wall and with said shoulder forms said groove, and wherein said locking means comprises screw means to force said upper chuck ring means toward said lower chuck body means thereby'to force said elastomeric gripping ring and said rotor base into engagement.

7. A centrifuge in accordance with claim 1 wherein said lower chuck body means and said upper chuck ring means are a single component and said gripping ring has a generally rectangular cross section with an upper integral triangular extension the lower exposed surface of which is adapted to make a tight fit with said inclined shoulder of said rotor base thereby to provide.

base of said rotor housing is about 45.

Claims (8)

1. In a centrifuge in which a rotor is held for high-speed rotation in a chuck mounted on a rotatable spindle, the combination of a rotor and a chuck adapted for quick engagement with said rotor through gripping means, said chuck comprising in combination a. lower chuck body means configured on its upper surface to comprise, from its center outwardly, a central shallow welL providing an engageable wall, an upwardly inclined surface, a first flat annular surface, and an upwardly extending wall having an internal surface and an essentially flat second annular surface; b. upper chuck ring means providing an angled internal surface, c. a groove defined by said second annular surface of said lower chuck body means and said angled internal surface of said upper chuck ring means; said rotor comprising d. a bottom member configured on its surface to comprise, from its center outwardly, a central circular alignment surface engaging said wall of said central shallow well of said chuck, an upwardly inclined surface essentially corresponding in area to said inclined surface of said lower chuck body means and spaced therefrom, and a peripheral flat annular surface engaging said first flat annular surface of said lower chuck body means, and e. rotor housing means joined to said bottom member and forming therewith a rotor base configured from the bottom up to have an outwardly inclined section, a lower vertical gripping section representing the maximum diameter of said rotor base and just clearing said internal surface of said upwardly extending wall of said lower chuck body means, an inwardly inclined gripping shoulder and an upper vertical section; forcing f. and gripping means comprising an elastomeric gripping ring held within said groove in said chuck in combination with locking means forcing said lower vertical gripping section and said inwardly inclined gripping shoulder of said rotor base into engagement with said gripping ring thereby to lock said rotor to said chuck through said gripping means.
2. A centrifuge in accordance with claim 1 wherein the angle defined between said outwardly inclined section of said rotor base and said internal surface of said upwardly extending wall of said lower chuck body means ranges between about 15* and 30*.
3. A centrifuge in accordance with claim 1 wherein the clearance between said lower vertical gripping section of said rotor base and said internal surface of said upwardly extending wall of said lower chuck body means ranges between about 0.008 and 0.015 inch.
4. A centrifuge in accordance with claim 1 wherein the ratio of the height of said rotor base, measured from said first flat annular surface of said lower chuck body means to the lower edge of said shoulder, to the outside diameter of said lower vertical gripping section of said rotor base ranges between about 0.02 and 0.05.
5. A centrifuge in accordance with claim 1 wherein the ratio of the height of said rotor base, measured from said first flat annular surface of said lower chuck body means to the lower edge of said lower vertical gripping section, to the height of said shoulder, measured from said first flat annular surface to the lower edge of said shoulder, ranges between about 0.2 and 0.6.
6. A centrifuge in accordance with claim 1 wherein said lower chuck body means is separate from said upper chuck ring means and includes a flat peripheral surface which surrounds said upwardly extending wall and is lower than said first flat annular surface; wherein said angled internal surface of said upper chuck ring means is defined by a lower vertical wall section, and an upper vertical wall section joined thereto through a shoulder, whereby a portion of said lower vertical wall section engages an external surface of said upwardly extending wall and with said shoulder forms said groove, and wherein said locking means comprises screw means to force said upper chuck ring means toward said lower chuck body means thereby to force said elastomeric gripping ring and said rotor base into engagement.
7. A centrifuge in accordance with claim 1 wherein said lower chuck body means and said upper chuck ring means are a single component and said gripping ring has a generally rectangular cross section with an upper inner integral triangular extension the Lower exposed surface of which is adapted to make a tight fit with said inclined shoulder of said rotor base thereby to provide said locking means integral with said gripping ring to form said gripping means.
8. A centrifuge in accordance with claim 1 wherein the angle of inclination of said inclined shoulder of the base of said rotor housing is about 45*.
US3785549A 1972-07-31 1972-07-31 Centrifuge chuck for disposable, snap-in centrifuge rotor Expired - Lifetime US3785549A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US27667772 true 1972-07-31 1972-07-31

Publications (1)

Publication Number Publication Date
US3785549A true US3785549A (en) 1974-01-15

Family

ID=23057645

Family Applications (1)

Application Number Title Priority Date Filing Date
US3785549A Expired - Lifetime US3785549A (en) 1972-07-31 1972-07-31 Centrifuge chuck for disposable, snap-in centrifuge rotor

Country Status (6)

Country Link
US (1) US3785549A (en)
JP (1) JPS5713345B2 (en)
CA (1) CA979869A (en)
DE (1) DE2328346C2 (en)
FR (1) FR2194488B1 (en)
GB (1) GB1436003A (en)

Cited By (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2745041A1 (en) * 1976-10-06 1978-04-13 Haemonetics Corp Plasmaphoresis device
US4684361A (en) * 1985-10-11 1987-08-04 Cardiovascular Systems, Inc. Centrifuge
US4692136A (en) * 1985-10-11 1987-09-08 Cardiovascular Systems Inc. Centrifuge
FR2595268A1 (en) * 1986-03-10 1987-09-11 Cardivascular Systems rotating mounting for fixing in position a centrifuge bowl during the rotation of a centrifuge
US4752284A (en) * 1986-12-05 1988-06-21 Biscar Jean P Artificial gravity intracellular molecular extraction
EP0278381A2 (en) * 1987-02-10 1988-08-17 DIDECO S.p.A. Chuck device for holding a cell for the centrifugation of blood, and the like
US4767396A (en) * 1987-03-03 1988-08-30 Haemonetics Corporation Method and apparatus for processing biological fluids
US4795419A (en) * 1985-10-11 1989-01-03 Kardiothor, Inc. Centrifuge
WO1989001827A1 (en) * 1987-09-04 1989-03-09 Haemonetics Corporation Portable centrifuge apparatus
US5062826A (en) * 1989-07-14 1991-11-05 Marco Mantovani Device for locking a blood centrifugation cell on a chuck
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube
US5344381A (en) * 1992-07-10 1994-09-06 Cabrera Y Lopez Caram Luis F Equipment for the elimination of light particles, inks and air from a fiber suspension for the manufacture of paper
US5591113A (en) * 1994-10-31 1997-01-07 Cobe Laboratories, Inc. Centrifugally assisted centrifuge bowl mount
US5658231A (en) * 1995-09-21 1997-08-19 Haemonetics Corporation Mechanism for securing a separation bowl to a mechanical chuck
US5851169A (en) * 1996-01-31 1998-12-22 Medtronic Electromedics, Inc. Rotary plate and bowl clamp for blood centrifuge
US5919125A (en) * 1997-07-11 1999-07-06 Cobe Laboratories, Inc. Centrifuge bowl for autologous blood salvage
US5964690A (en) * 1997-03-19 1999-10-12 Medtronic, Inc. Mechanism for fixing a blood centrifuge bowl to a rotating spindle
US5976388A (en) * 1997-05-20 1999-11-02 Cobe Cardiovascular Operating Co., Inc. Method and apparatus for autologous blood salvage
WO2001076759A1 (en) * 2000-04-11 2001-10-18 Medicept, Inc. Sealed centrifugal clarifier
US6315707B1 (en) 1999-09-03 2001-11-13 Baxter International Inc. Systems and methods for seperating blood in a rotating field
US6322488B1 (en) 1999-09-03 2001-11-27 Baxter International Inc. Blood separation chamber with preformed blood flow passages and centralized connection to external tubing
US20020077241A1 (en) * 1999-09-03 2002-06-20 Baxter International Inc. Blood processing systems and methods with quick attachment of a blood separation chamber to a centrifuge rotor
US6524231B1 (en) 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US20040082458A1 (en) * 1999-09-03 2004-04-29 Baxter International Inc. Blood processing systems and methods with umbilicus-driven blood processing chambers
US20040082459A1 (en) * 2002-10-24 2004-04-29 Baxter International Inc. Blood processing systems and methods for collecting plasma free or essentially free of cellular blood components
US20040195190A1 (en) * 2002-10-24 2004-10-07 Kyungyoon Min Separation apparatus and method
US20050109716A1 (en) * 2002-05-24 2005-05-26 Michael Leach Apparatus and method for separating and concentrating fluids containing multiple components
US20060175244A1 (en) * 2005-02-07 2006-08-10 Hanuman Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US20060175242A1 (en) * 2005-02-07 2006-08-10 Hanuman Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
US20060199720A1 (en) * 2005-01-21 2006-09-07 Tien-Chu Juan Plasmapheresis centrifuge bowl
US20060273050A1 (en) * 2002-05-24 2006-12-07 Higgins Joel C Apparatus and method for separating and concentrating fluids containing multiple components
US20070034579A1 (en) * 2002-05-03 2007-02-15 Randel Dorian Methods and apparatus for isolating platelets from blood
US20070276191A1 (en) * 2006-05-26 2007-11-29 Sean Selover Illuminated surgical access system including a surgical access device and integrated light emitter
US20080011684A1 (en) * 2005-02-07 2008-01-17 Dorian Randel E Apparatus and method for preparing platelet rich plasma and concentrates thereof
US20080124700A1 (en) * 2006-11-27 2008-05-29 Matteo Fortini Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl
US20080153686A1 (en) * 2005-01-25 2008-06-26 Jean-Denis Rochat Disposable Device for the Continuous Centrifugal Separation of a Physiological Fluid
US20080217265A1 (en) * 2002-05-24 2008-09-11 Biomet Manufacturing Corp. Apparatus And Method for Separating And Concentrating Fluids Containing Multiple Components
US20080283474A1 (en) * 2007-04-12 2008-11-20 Biomet Biologics, Llc Buoy suspension fractionation system
US20090221075A1 (en) * 2008-02-29 2009-09-03 Biomet Manufacturing Corp. System And Process For Separating A Material
US20090289014A1 (en) * 2008-05-23 2009-11-26 Biomet Biologics, Llc Blood Separating Device
US20090305863A1 (en) * 2008-06-10 2009-12-10 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US20100256595A1 (en) * 2009-04-03 2010-10-07 Biomet Biologics, Llc All-In-One Means Of Separating Blood Components
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US20110014705A1 (en) * 2009-07-16 2011-01-20 Biomet Biologics, Llc Method and apparatus for separating biological materials
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US20110237418A1 (en) * 2006-03-07 2011-09-29 Jacques Chammas Rotor defining a fluid separation chamber of varying volume
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US8986238B2 (en) 2012-08-15 2015-03-24 Cyclone Medtech, Inc. Systems and methods for salvaging red blood cells for autotransfusion
US9308314B2 (en) 2011-04-08 2016-04-12 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation
CN106139649A (en) * 2015-04-07 2016-11-23 四川南格尔生物科技有限公司 Blood ingredient separation cup dynamic sealing system
US9556243B2 (en) 2013-03-15 2017-01-31 Biomet Biologies, LLC Methods for making cytokine compositions from tissues using non-centrifugal methods
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9701728B2 (en) 2008-02-27 2017-07-11 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9897589B2 (en) 2002-05-24 2018-02-20 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL94802C (en) * 1985-10-11
JPS6279555U (en) * 1986-10-30 1987-05-21
DE10311168B4 (en) * 2003-03-12 2006-05-11 Westfalia Separator Ag Centrifugal drum for a separator

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US610058A (en) * 1898-08-30 Frederick george jones
US3581981A (en) * 1945-03-02 1971-06-01 Cryogenic Technology Inc Centrifuge chuck

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US610058A (en) * 1898-08-30 Frederick george jones
US3581981A (en) * 1945-03-02 1971-06-01 Cryogenic Technology Inc Centrifuge chuck

Cited By (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2745041A1 (en) * 1976-10-06 1978-04-13 Haemonetics Corp Plasmaphoresis device
US4692136A (en) * 1985-10-11 1987-09-08 Cardiovascular Systems Inc. Centrifuge
US4684361A (en) * 1985-10-11 1987-08-04 Cardiovascular Systems, Inc. Centrifuge
US4795419A (en) * 1985-10-11 1989-01-03 Kardiothor, Inc. Centrifuge
FR2595268A1 (en) * 1986-03-10 1987-09-11 Cardivascular Systems rotating mounting for fixing in position a centrifuge bowl during the rotation of a centrifuge
US4718888A (en) * 1986-03-10 1988-01-12 Cardiovascular Systems, Inc. Centrifuge bowl mount
US4752284A (en) * 1986-12-05 1988-06-21 Biscar Jean P Artificial gravity intracellular molecular extraction
EP0278381A3 (en) * 1987-02-10 1989-01-25 Dideco S.P.A. Chuck device for holding a cell for the centrifugation of blood, and the like
EP0278381A2 (en) * 1987-02-10 1988-08-17 DIDECO S.p.A. Chuck device for holding a cell for the centrifugation of blood, and the like
US4767396A (en) * 1987-03-03 1988-08-30 Haemonetics Corporation Method and apparatus for processing biological fluids
WO1989001827A1 (en) * 1987-09-04 1989-03-09 Haemonetics Corporation Portable centrifuge apparatus
US4889524A (en) * 1987-09-04 1989-12-26 Haemonetics Corporation Portable centrifuge apparatus
US5062826A (en) * 1989-07-14 1991-11-05 Marco Mantovani Device for locking a blood centrifugation cell on a chuck
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube
US5344381A (en) * 1992-07-10 1994-09-06 Cabrera Y Lopez Caram Luis F Equipment for the elimination of light particles, inks and air from a fiber suspension for the manufacture of paper
US5591113A (en) * 1994-10-31 1997-01-07 Cobe Laboratories, Inc. Centrifugally assisted centrifuge bowl mount
US5658231A (en) * 1995-09-21 1997-08-19 Haemonetics Corporation Mechanism for securing a separation bowl to a mechanical chuck
US5851169A (en) * 1996-01-31 1998-12-22 Medtronic Electromedics, Inc. Rotary plate and bowl clamp for blood centrifuge
US5964690A (en) * 1997-03-19 1999-10-12 Medtronic, Inc. Mechanism for fixing a blood centrifuge bowl to a rotating spindle
US5976388A (en) * 1997-05-20 1999-11-02 Cobe Cardiovascular Operating Co., Inc. Method and apparatus for autologous blood salvage
US5919125A (en) * 1997-07-11 1999-07-06 Cobe Laboratories, Inc. Centrifuge bowl for autologous blood salvage
US7789245B2 (en) 1999-09-03 2010-09-07 Fenwal, Inc. Blood separation chamber
US6315707B1 (en) 1999-09-03 2001-11-13 Baxter International Inc. Systems and methods for seperating blood in a rotating field
US6322488B1 (en) 1999-09-03 2001-11-27 Baxter International Inc. Blood separation chamber with preformed blood flow passages and centralized connection to external tubing
US20020077241A1 (en) * 1999-09-03 2002-06-20 Baxter International Inc. Blood processing systems and methods with quick attachment of a blood separation chamber to a centrifuge rotor
US6524231B1 (en) 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US20090291819A1 (en) * 1999-09-03 2009-11-26 Fenwal, Inc. Blood separation chamber
US20030203802A1 (en) * 1999-09-03 2003-10-30 Baxter International Inc. Blood separation chamber with preformed blood flow passages and centralized connection to external tubing
US20030203801A1 (en) * 1999-09-03 2003-10-30 Baxter International, Inc. Red blood cell separation method
US20040082458A1 (en) * 1999-09-03 2004-04-29 Baxter International Inc. Blood processing systems and methods with umbilicus-driven blood processing chambers
US7166231B2 (en) 1999-09-03 2007-01-23 Baxter International Inc. Red blood cell separation method
US20060032817A1 (en) * 1999-09-03 2006-02-16 Tom Westberg Separation apparatus
US6800054B2 (en) 1999-09-03 2004-10-05 Baxter International Inc. Blood separation chamber with preformed blood flow passages and centralized connection to external tubing
US6860846B2 (en) 1999-09-03 2005-03-01 Baxter International Inc. Blood processing systems and methods with umbilicus-driven blood processing chambers
WO2001076759A1 (en) * 2000-04-11 2001-10-18 Medicept, Inc. Sealed centrifugal clarifier
US6602413B2 (en) 2000-04-11 2003-08-05 Medicept, Inc. Sealed centrifugal clarifier
US8950586B2 (en) 2002-05-03 2015-02-10 Hanuman Llc Methods and apparatus for isolating platelets from blood
US20070034579A1 (en) * 2002-05-03 2007-02-15 Randel Dorian Methods and apparatus for isolating platelets from blood
US7470371B2 (en) 2002-05-03 2008-12-30 Hanuman Llc Methods and apparatus for isolating platelets from blood
US8187477B2 (en) 2002-05-03 2012-05-29 Hanuman, Llc Methods and apparatus for isolating platelets from blood
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US20090101599A1 (en) * 2002-05-03 2009-04-23 Hanuman, L.L.C. Methods And Apparatus For Isolating Platelets From Blood
US7837884B2 (en) 2002-05-03 2010-11-23 Hanuman, Llc Methods and apparatus for isolating platelets from blood
US20060273050A1 (en) * 2002-05-24 2006-12-07 Higgins Joel C Apparatus and method for separating and concentrating fluids containing multiple components
US8062534B2 (en) 2002-05-24 2011-11-22 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8048321B2 (en) 2002-05-24 2011-11-01 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20110168193A1 (en) * 2002-05-24 2011-07-14 Biomet Biologics, Llc Apparatus and Method for Separating and Concentrating Fluids Containing Multiple Components
US7914689B2 (en) 2002-05-24 2011-03-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20110056893A1 (en) * 2002-05-24 2011-03-10 Biomet Biologics, LLC. Apparatus and Method for Separating and Concentrating Fluids Containing Multiple Components
US8163184B2 (en) 2002-05-24 2012-04-24 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8603346B2 (en) 2002-05-24 2013-12-10 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20080217265A1 (en) * 2002-05-24 2008-09-11 Biomet Manufacturing Corp. Apparatus And Method for Separating And Concentrating Fluids Containing Multiple Components
US20080217264A1 (en) * 2002-05-24 2008-09-11 Biomet Manufacturing Corp. Apparatus And Method For Separating And Concentrating Fluids Containing Multiple Components
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US8808551B2 (en) 2002-05-24 2014-08-19 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20050109716A1 (en) * 2002-05-24 2005-05-26 Michael Leach Apparatus and method for separating and concentrating fluids containing multiple components
US9897589B2 (en) 2002-05-24 2018-02-20 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9114334B2 (en) 2002-05-24 2015-08-25 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US7780860B2 (en) 2002-05-24 2010-08-24 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US6849039B2 (en) 2002-10-24 2005-02-01 Baxter International Inc. Blood processing systems and methods for collecting plasma free or essentially free of cellular blood components
US20040195190A1 (en) * 2002-10-24 2004-10-07 Kyungyoon Min Separation apparatus and method
US7297272B2 (en) 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
US7918350B2 (en) 2002-10-24 2011-04-05 Fenwal, Inc. Separation apparatus and method
US20040082459A1 (en) * 2002-10-24 2004-04-29 Baxter International Inc. Blood processing systems and methods for collecting plasma free or essentially free of cellular blood components
US20090218277A1 (en) * 2002-10-24 2009-09-03 Kyungyoon Min Separation apparatus and method
US20080087614A1 (en) * 2002-10-24 2008-04-17 Kyungyoon Min Separation Apparatus and Method
US20080087601A1 (en) * 2002-10-24 2008-04-17 Kyungyoon Min Separation Apparatus and Method
US20060199720A1 (en) * 2005-01-21 2006-09-07 Tien-Chu Juan Plasmapheresis centrifuge bowl
US8348823B2 (en) 2005-01-25 2013-01-08 Jean-Denis Rochat Disposable device for the continuous centrifugal separation of a physiological fluid
US8070664B2 (en) * 2005-01-25 2011-12-06 Jean-Denis Rochat Disposable device for the continuous centrifugal separation of a physiological fluid
US20080153686A1 (en) * 2005-01-25 2008-06-26 Jean-Denis Rochat Disposable Device for the Continuous Centrifugal Separation of a Physiological Fluid
US8105495B2 (en) 2005-02-07 2012-01-31 Hanuman, Llc Method for preparing platelet rich plasma and concentrates thereof
US7866485B2 (en) 2005-02-07 2011-01-11 Hanuman, Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US20110042296A1 (en) * 2005-02-07 2011-02-24 Hanuman Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US20060175242A1 (en) * 2005-02-07 2006-08-10 Hanuman Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
US20080011684A1 (en) * 2005-02-07 2008-01-17 Dorian Randel E Apparatus and method for preparing platelet rich plasma and concentrates thereof
EP2666494A3 (en) * 2005-02-07 2014-04-23 Hanuman LLC Platelet rich plasma concentrate apparatus and method
WO2006086201A2 (en) 2005-02-07 2006-08-17 Hanuman Llc Platelet rich plasma concentrate apparatus and method
US7987995B2 (en) 2005-02-07 2011-08-02 Hanuman, Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
US7824559B2 (en) 2005-02-07 2010-11-02 Hanumann, LLC Apparatus and method for preparing platelet rich plasma and concentrates thereof
US20060175244A1 (en) * 2005-02-07 2006-08-10 Hanuman Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US8133389B2 (en) 2005-02-07 2012-03-13 Hanuman, Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
US20100206798A1 (en) * 2005-02-07 2010-08-19 Hanuman Llc Method And Apparatus For Preparing Platelet Rich Plasma And Concentrates Thereof
US7708152B2 (en) 2005-02-07 2010-05-04 Hanuman Llc Method and apparatus for preparing platelet rich plasma and concentrates thereof
WO2006086201A3 (en) * 2005-02-07 2006-11-09 Hanuman Llc Platelet rich plasma concentrate apparatus and method
US8096422B2 (en) 2005-02-07 2012-01-17 Hanuman Llc Apparatus and method for preparing platelet rich plasma and concentrates thereof
US20110237418A1 (en) * 2006-03-07 2011-09-29 Jacques Chammas Rotor defining a fluid separation chamber of varying volume
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US20070276191A1 (en) * 2006-05-26 2007-11-29 Sean Selover Illuminated surgical access system including a surgical access device and integrated light emitter
US8506825B2 (en) 2006-11-27 2013-08-13 Sorin Group Italia S.R.L. Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl
US20080124700A1 (en) * 2006-11-27 2008-05-29 Matteo Fortini Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl
US9138664B2 (en) 2007-04-12 2015-09-22 Biomet Biologics, Llc Buoy fractionation system
US7806276B2 (en) 2007-04-12 2010-10-05 Hanuman, Llc Buoy suspension fractionation system
US8119013B2 (en) 2007-04-12 2012-02-21 Hanuman, Llc Method of separating a selected component from a multiple component material
US20080283474A1 (en) * 2007-04-12 2008-11-20 Biomet Biologics, Llc Buoy suspension fractionation system
US9649579B2 (en) 2007-04-12 2017-05-16 Hanuman Llc Buoy suspension fractionation system
US8596470B2 (en) 2007-04-12 2013-12-03 Hanuman, Llc Buoy fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US9701728B2 (en) 2008-02-27 2017-07-11 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
US20090221075A1 (en) * 2008-02-29 2009-09-03 Biomet Manufacturing Corp. System And Process For Separating A Material
US20130196425A1 (en) * 2008-02-29 2013-08-01 Biomet Biologics, Llc System and Process for Separating a Material
US9719063B2 (en) 2008-02-29 2017-08-01 Biomet Biologics, Llc System and process for separating a material
US8801586B2 (en) * 2008-02-29 2014-08-12 Biomet Biologics, Llc System and process for separating a material
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US8012077B2 (en) 2008-05-23 2011-09-06 Biomet Biologics, Llc Blood separating device
US20090289014A1 (en) * 2008-05-23 2009-11-26 Biomet Biologics, Llc Blood Separating Device
US20090305863A1 (en) * 2008-06-10 2009-12-10 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US7993257B2 (en) * 2008-06-10 2011-08-09 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US8262552B2 (en) * 2008-06-10 2012-09-11 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US8485957B2 (en) * 2008-06-10 2013-07-16 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US8783470B2 (en) 2009-03-06 2014-07-22 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8187475B2 (en) 2009-03-06 2012-05-29 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8992862B2 (en) 2009-04-03 2015-03-31 Biomet Biologics, Llc All-in-one means of separating blood components
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US20100256595A1 (en) * 2009-04-03 2010-10-07 Biomet Biologics, Llc All-In-One Means Of Separating Blood Components
US20110014705A1 (en) * 2009-07-16 2011-01-20 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9533090B2 (en) 2010-04-12 2017-01-03 Biomet Biologics, Llc Method and apparatus for separating a material
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US9308314B2 (en) 2011-04-08 2016-04-12 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation
US9239276B2 (en) 2011-04-19 2016-01-19 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8986238B2 (en) 2012-08-15 2015-03-24 Cyclone Medtech, Inc. Systems and methods for salvaging red blood cells for autotransfusion
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9556243B2 (en) 2013-03-15 2017-01-31 Biomet Biologies, LLC Methods for making cytokine compositions from tissues using non-centrifugal methods
US9713810B2 (en) 2015-03-30 2017-07-25 Biomet Biologics, Llc Cell washing plunger using centrifugal force
CN106139649A (en) * 2015-04-07 2016-11-23 四川南格尔生物科技有限公司 Blood ingredient separation cup dynamic sealing system
US9757721B2 (en) 2015-05-11 2017-09-12 Biomet Biologics, Llc Cell washing plunger using centrifugal force

Also Published As

Publication number Publication date Type
CA979869A (en) 1975-12-16 grant
JP1120139C (en) grant
FR2194488B1 (en) 1978-06-30 grant
JPS5713345B2 (en) 1982-03-16 grant
CA979869A1 (en) grant
DE2328346A1 (en) 1974-02-14 application
FR2194488A1 (en) 1974-03-01 application
DE2328346C2 (en) 1985-06-13 grant
JPS4958463A (en) 1974-06-06 application
GB1436003A (en) 1976-05-19 application

Similar Documents

Publication Publication Date Title
US3434615A (en) Centrifuge bottle and closure therefor
US3360155A (en) Rapid seal closure for containers
US4957637A (en) Serum separator system for centrifuge with piercable membrane
US4738655A (en) Apparatus and method for obtaining a rapid hematocrit
US6629919B2 (en) Core for blood processing apparatus
US4998622A (en) Plastic pail and lid
US5980734A (en) Auxiliary apparatus for sampling blood serum
US20030053938A1 (en) Liquid specimen collection container
US3962085A (en) Skimmer assembly
US3856483A (en) Method and device for degassing liquids
US4889524A (en) Portable centrifuge apparatus
US3864089A (en) Multiple-sample rotor assembly for blood fraction preparation
US5037544A (en) Keyed column chromatography apparatus
US4840612A (en) Centrifugal separator and method of operating same
US5851169A (en) Rotary plate and bowl clamp for blood centrifuge
US4068798A (en) Method and apparatus for stopper removal
US6216340B1 (en) Automatic handling of sample cups closed with a screwable cap
US4251366A (en) Adapter for laboratory filter
US4847205A (en) Device and method for automated separation of a sample of whole blood into aliquots
US7077273B2 (en) Blood component separator disk
US4846974A (en) Centrifuge system and fluid container therefor
US2822126A (en) Continuous feed centrifuge
US5558616A (en) Centrifuge rotor cover having container supports thereon
US4391710A (en) Cytocentrifuge
US5795489A (en) Centrifugal filtration method

Legal Events

Date Code Title Description
AS Assignment

Owner name: AMERICAN HOSPITAL SPPLY CORPORATION, ONE AMERICAN

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:HAEMONETICS CORPORATION, A CORP. OF DE.;REEL/FRAME:004483/0821

Effective date: 19850514

AS Assignment

Owner name: FLEET CREDIT CORPORATION

Free format text: SECURITY INTEREST;ASSIGNOR:LATHAM LABS, INC., A CORP. OF MA.;REEL/FRAME:004520/0794

Owner name: FLEET NATIONAL BANK, A NATIONAL BANKING ASSOCIATIO

Free format text: SECURITY INTEREST;ASSIGNOR:LATHAM LABS, INC., A CORP. OF MA.;REEL/FRAME:004520/0794

AS Assignment

Owner name: HAEMONETICS CORPORATION

Free format text: CHANGE OF NAME;ASSIGNOR:LATHAM LABS, INC. (CHANGED TO);REEL/FRAME:004550/0115

Effective date: 19860423

Owner name: LATHAM LABS, INC., 400 WOOD ROAD, BRAINTREE, MASSA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:AMERICAN HOSPITAL SUPPLY CORPORATION, A CORP OF IL.;REEL/FRAME:004550/0850

Effective date: 19851120

Owner name: HAEMONETICS CORPORATION, MASSACHUSETTS

Owner name: LATHAM LABS, INC., MASSACHUSETTS

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:AMERICAN HOSPITAL SUPPLY CORPORATION, A CORP OF IL.;REEL/FRAME:004550/0850

AS Assignment

Owner name: HAEMONETICS CORPORATION, A MASSACHUSETTS CORP.

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:FLEET NATIONAL BANK;REEL/FRAME:004598/0821

Effective date: 19860601

Owner name: HAEMONETICS CORPORATION, A MASSACHUSETTS CORP.,STA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:FLEET NATIONAL BANK;REEL/FRAME:004598/0821