US3776220A - Diagnostic swab with stored culture medium - Google Patents

Diagnostic swab with stored culture medium Download PDF

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Publication number
US3776220A
US3776220A US3776220DA US3776220A US 3776220 A US3776220 A US 3776220A US 3776220D A US3776220D A US 3776220DA US 3776220 A US3776220 A US 3776220A
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Prior art keywords
tube
swab
device
medium
seal
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F Monaghan
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F Monaghan
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0096Casings for storing test samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/38Swabs having a stick-type handle, e.g. cotton tips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/02Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by impregnation, e.g. using swabs or loops
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/22Means for packing or storing viable microorganisms

Abstract

This invention relates to a disposable device for housing diagnostic swabs or similar devices comprising a plastic tube containing medium in a breakable sealed section, a swab in a second section adapted so that the swab can break the seal separating it from the medium and a third seal located on the opposite side of the swab from the medium.

Description

United States Patent 11 1 Monaghan 1 Dec. 4, 1973 [54] DIAGNOSTIC SWAB WITH STORED 3,163,160 12/1964 Cohen 128/2 w CULTURE MEDIUM 2,835,246 5/1958 Boettger... 128/2 W 3,640,268 2/1972 Davis 128/2 W [76] Inventor: Fr nk M n gh n, 5 South 3,308,039 3/1967 Nelson 12s/w x Glendale, Calif. [22] Filed: May 9 1972 Primary ExaminerAldrich F. Medbery Atz0rney-Sanford Astor [21] Appl. No.: 251,658

, [57] ABSTRACT 152] 11.8. CL. 128/2 W, 128/269 This invention relates to a disposable device for hous- [51 Int. Cl A61m 35/00 ing diagnostic swabs or similar devices comprising a [58] Field of Search 128/2 R, 2 W, 269, plastic tube containing medium in a breakable sealed 128/2 G section, a swab in a second section adapted so that the swab can break the seal separating it from the medium [56] References Cited and a third seal located on the opposite side of the UNITED STATES PATENTS Swab from the medium- 2,100,157 11/1937 Chandler 128/269 4 Claims, 5 Drawing Figures DIAGNOSTIC SWAB WITH STORED CULTURE MEDIUM BACKGROUND OF THE INVENTION In the usual use of a swab, one is taken from a batch of sterile swabs and then applied or rubbed against the tissue concerned to secure a sample of any-offending bacteria which may be present to verify a diagnosis. This being done, the swab is then placed in a sterile container which is sent to the laboratory where it is removed and then placed in another container such as a Petri dish, said container having a culture medium therein, after which the dish is then placed in an incubator to grow any colonies which may be present. The growth secured, samples of said growth are taken from the dish for examination. Once finished with, the dish must then be carefully cleaned and sterilized properly in order that it may be reused. The swab of course is discarded. Although the foregoing method is effective, it is cumbersome, time wasting and complicated to insure a definite clean sterile container for future use.

This invention presents a novel means of not only keeping the swab in an individual disposable and unbreakable container, but that container also may hold the culture medium necessary for the swab, both products being housed separately within said container until time of use of the device. At the proper time the swab is used, returned to the container, brought into contact with the culture medium and the entire unit may be placed in the incubator, and the sought for colonies grown in said culture medium right in the container. A sample is taken from that medium, and then the entire unit, the swab, the culture medium and its grown infection is immediately discarded to an incinerator for removal.

This invention then presents a device that definitely insures complete sterility for the products, ease of use, saving of labor in not having parts to clean and sterilize afterward, complete disposability, and a product which is inexpensive to produce.

The methods presently in existence all use glass tubing in which a glass ampule must be broken to release any fluid medium present. Also the swab end is broken off to fit inside of a glass tube and thus the operator must do extra work and come in contact with the swabs, itself compromising the sterility of the operation and test.

SUMMARY OF THE INVENTION Accordingly, it is an object of the present invention to provide a novel disposable and unbreakable plastic tube device containing a medium sealed in the tube.

Another object of the present invention is to provide a disposable tube device containing both a swab and a medium in sealed portion which can be brought together when needed.

Yet another object of the present invention is to provide a disposable culture tube that insures complete sterility in that even the swab is never touched by the operator.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 illustrates the front view of the plastic tube device of the present invention FIG. 2 illustrates a side view of the device.

FIG. 3 illustrates the upper portion of said device.

FIG. 4 illustrates thelower portion of said device.

FIG. 5 illustrates the device after use. As shown in the figures above-mentioned, the present invention comprises a plastic tube device with an upper or swab-holding portion 10, shown alone in FIG. 3 which is a piece of hollow plastic tubing sealed at one end 12.

The seal 12 is shaped in such a way that it frictionally holds the shaft end .of a common swab 14, having a cotton pad 16. The device may also hold other elongated medical devices as well, such as a hypodermic.

The device of the present invention has a lower or medium holding portion 18, shown alone in FIG. 4 which is a piece of hollow plastic tubing sealed at the end 20 and having a breakable seal 22 located between the two ends of the lower portion 18 creating a closed sealed chamber 24 within lower portion 18.

Located adjacent medium chamber 24 is a second chamber 15 defined by the outer chamber wall 17 of lower portion 18 and a seal 19 which extends partially across the diameter of the lower tube 18 between seal 22 and the open end 26 of portion 18. This second chamber 15 with seal 19 has two important functions.

First and most importantly, when the swab 14 is forced through breakable seal 22 into the medium chamber 24 and into a liquid medium 30, seal 19 prevents the liquid 30 from shooting up the tube 18 as will happen without the presence of seal 19. This confines the liquid below seal 19.

Seal 19 extends only partially across the diameter of tube 18 sufficiently so that the combination of seal 19 and swab 14 effectively block the opening of tube 18 to confine liquid 30.

Secondly, seal 19 serves to hold swab 14 more securely in position during handling since seal 19 exerts some frictional pressure on swab 14 and in addition the greater diameter of the cotton pad 16 makes it more difficult for the swab to slip out through seal 19 and fall out of tube 18.

The hollow plastic tubing used to make the device of the present invention is well known in the art and may be manu-factured by a continuous extrusion process also well known.

The sealing and cutting of the tubing into the sizes and shapes necessary may be done with a machine such as that described in my US. Pat. No. 3,700,529 issued Oct. 24, 1972.

The upper edge 26 of lower portion 18 is open and is preferably slanted at an angle relative to the lower edge 28 of the upper portion 10 which is open and preferably horizontal so that the two portions 10 and 18 can be more easily slidingly engaged.

The upper portion 10 has a slightly larger diameter than lower portion 18 so that the upper portion 10 can easily slide over lower portion to fit snugly together. The edges 26 and 28 which must slide over each other may both be horizontal but making one of the edges slanted makes it much easier for the operator to put the two parts together.

The closed chamber 24 is filled just prior to scaling with a liquid medium 30. This may be any medium desired depending upon the particular test or result desired.

At the time of use the operator takes the device of the present invention, which has been sterilized by any of many known methods such as heat, or radiation, and removes the upper portion 10 which holds the swab 14. The operator then takes the sample he desires by swabbing the location to be tested with the cotton pad 16 of swab 14 and then replaces upper por-tion by sliding it over lower portion 18. Because swab 14 is constantly covered by upper portion 10 the operator never has to directly touch swab 14.

By exerting downward pressure on the upper portion 10, swab l4 breaks through breakable seal 22, as shown in FIG. 5, and the cotton pad 16 is immersed in medium 30.

The device may be used as a transport tube where the medium 30 is used to keep the bacteria alive until the tube is taken to the laboratory and it can be transferred to a Petri dish, or as stated the tube itself may be placed in the incubator to grow the culture. Other uses can be made of the present device such as conducting a test in the tube itself where the medium 30 is one that changes color upon introduction of a certain substance,

It will be obvious to those skilled in the art that various modifications of the present invention may be resorted to in a manner limited only by a just interpretation of the following claims.

I claim:

1. A disposable culture tube device comprising:

a. An upper plastic tube open at one end and sealed at the other;

b. The seal being shaped so as to frictionally hold the end of an elongated medical device;

c. A lower plastic tube open at one end and sealed at the other, having a chamber fomied by; d. a flat welded breakable seal section for closing the plastic tube between its ends;

e. A liquid medium within the chamber;

f. A second seal partially across the diameter of said tube spaced from and adjacent said breakable seal;

g. The upper and lower tubes shaped to fit tightly together.

2. The device of claim 1 wherein the elongated medical device is a sterile swab.

3. The device of claim 1 wherein the open end of the lower tube is cut at an angle relative to the open end of the upper tube.

4. The device of claim 1 wherein the upper tube has a diameter larger than the lower tube so that the upper tube slides frictionally over the lower tube.

Claims (4)

1. A disposable culture tube device comprising: a. An upper plastic tube open at one end and sealed at the other; b. The seal being shaped so as to frictionally hold the end of an elongated medical device; c. A lower plastic tube open at one end and sealed at the other, having a chamber formed by; d. a flat welded breakable seal section for closing the plastic tube between its ends; e. A liquid medium within the chamber; f. A second seal partially across the diameter of said tube spaced from and adjacent said breakable seal; g. The upper and lower tubes shaped to fit tightly together.
2. The device of claim 1 wherein the elongated medical device is a sterile swab.
3. 3 The device of claim 1 wherein the open end of the lower tube is cut at an angle relative to the open end of the upper tube.
4. The device of claim 1 wherein the upper tube has a diameter larger than the lower tube so that the upper tube slides frictionally over the lower tube.
US3776220A 1972-05-09 1972-05-09 Diagnostic swab with stored culture medium Expired - Lifetime US3776220A (en)

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Cited By (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3890954A (en) * 1973-05-08 1975-06-24 U S Medical Research & Dev Inc Method of and apparatus for collecting cultures
US3913562A (en) * 1974-01-16 1975-10-21 Moore Perk Corp Disposable package for collecting and transporting cultures for laboratory analysis
US3918435A (en) * 1974-01-24 1975-11-11 Miles Lab Transport swab tube
US4014746A (en) * 1973-05-08 1977-03-29 U.S. Medical Research And Development, Inc. Method of and apparatus for collecting cultures
US4184483A (en) * 1973-05-08 1980-01-22 U.S. Medical Research & Development, Inc. Method of and apparatus for collecting cultures
US4353868A (en) * 1981-05-29 1982-10-12 Sherwood Medical Industries Inc. Specimen collecting device
US4387725A (en) * 1981-02-10 1983-06-14 Mull John D Device for use in the collection and transportation of medical specimens
WO1983003047A1 (en) * 1982-03-01 1983-09-15 E & K Corp Method and apparatus for collecting and/or growing protected biological specimens
US4409988A (en) * 1973-05-08 1983-10-18 Donald J. Greenspan Apparatus for collecting cultures
EP0155747A1 (en) * 1984-03-19 1985-09-25 Kidde, Inc. Tube culture system
WO1986003395A1 (en) * 1984-12-03 1986-06-19 Accu-Med Corporation Apparatus for collecting and/or growing protected biological cultures
US4633886A (en) * 1985-05-02 1987-01-06 Bucaro Jr Russell J Device for home detection of cervical and vaginal cancer
US4637061A (en) * 1985-12-20 1987-01-13 Riese J Richard Specimen, sample collection and transport container
US4685578A (en) * 1986-09-10 1987-08-11 Minnesota Mining And Manufacturing Company Tamper indication system
US4707450A (en) * 1986-09-25 1987-11-17 Nason Frederic L Specimen collection and test unit
US4769333A (en) * 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4838851A (en) * 1986-11-26 1989-06-13 Shabo Alan L Applicator and package therefor
US4859603A (en) * 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
EP0354704A1 (en) * 1988-08-01 1990-02-14 Adi Diagnostics Inc. Medical swab device
US4952204A (en) * 1988-08-10 1990-08-28 Gam-Med Packaging Corporation Dry handle swab assembly and unit
US4978504A (en) * 1988-02-09 1990-12-18 Nason Frederic L Specimen test unit
US4978502A (en) * 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US5078968A (en) * 1988-02-09 1992-01-07 Nason Frederic L Specimen test unit
US5238649A (en) * 1988-02-09 1993-08-24 Nason Frederic L Specimen test unit
US5246856A (en) * 1989-01-26 1993-09-21 Scan-Labs Ltd. Specimen receptacles for swabbing sets
US5260031A (en) * 1990-12-18 1993-11-09 Saliva Diagnostic Systems, Inc. Saliva sampling device with sample adequacy indicating system
US5266266A (en) * 1988-02-09 1993-11-30 Nason Frederic L Specimen test unit
EP0572637A1 (en) * 1990-12-13 1993-12-08 NASON, Frederic L. Specimen test unit
WO1995019447A1 (en) * 1994-01-14 1995-07-20 The Jockey Club Non-invasive sampling method for nucleic acid analysis
EP0734684A1 (en) * 1995-03-30 1996-10-02 Ortho Pharmaceutical Corporation In home oral fluid sample collection device and package for mailing of such device
US5827675A (en) * 1995-07-12 1998-10-27 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US5826600A (en) * 1997-09-29 1998-10-27 National Healthcare Products, Ltd. Disposable dry-handle mascara applicator assembly
US5869003A (en) * 1998-04-15 1999-02-09 Nason; Frederic L. Self contained diagnostic test unit
US5879635A (en) * 1997-03-31 1999-03-09 Nason; Frederic L. Reagent dispenser and related test kit for biological specimens
US5965453A (en) * 1995-07-12 1999-10-12 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
EP0960825A2 (en) 1998-05-28 1999-12-01 Becton Dickinson and Company Blister-type device for transporting biological or chemical samples
US6248294B1 (en) 1998-04-15 2001-06-19 Frederic L. Nason Self contained diagnostic test unit
US6312395B1 (en) 1999-06-29 2001-11-06 Innovative Genetic Technology Cell collection and transport
US20020197738A1 (en) * 2001-06-21 2002-12-26 Gc Corporation Pretreatment instrument of saliva and pretreatment method of saliva
US6516947B1 (en) 2000-08-11 2003-02-11 Viridian Packaging Solutions, Llc Containers having a fracture recess for opening the containers
WO2002085240A3 (en) * 2001-04-20 2004-03-11 3M Innovative Properties Co Container for multiple-component compositions
WO2004038382A1 (en) * 2002-10-09 2004-05-06 Sunstar Inc. Sputum-collecting tool
US20050009200A1 (en) * 2003-07-11 2005-01-13 Huiyan Guo Sanitary and compact fecal occult blood collector
US20050084842A1 (en) * 2003-10-20 2005-04-21 O'connor Amanda L. Diagnostic test device and method of using same
US20070178606A1 (en) * 2005-09-27 2007-08-02 Sysmex Corporation Chromatography kit, examination container, and method for manufacturing the same
US20070208274A1 (en) * 2006-03-03 2007-09-06 Capitol Vial Inc. Sample Collection System And Method
US20080206740A1 (en) * 2004-12-22 2008-08-28 Skiffington Richard T Sampling Method and Device
US20090202393A1 (en) * 2008-02-13 2009-08-13 Capitol Vial Inc. Fluid sample collection system
US20090209044A1 (en) * 2008-02-13 2009-08-20 Capitol Vial Inc. Fluid Sample Collection System and Method
US20100136670A1 (en) * 2007-05-04 2010-06-03 Markovsky Robert J Sampling Method and Device
US20100285572A1 (en) * 2006-05-09 2010-11-11 Salter Robert S Inhibition Assay Method and Device for Detection of Antibiotics
US20110146419A1 (en) * 2008-02-15 2011-06-23 Gonzalez Bernard A Sample acquisition device
US20110179887A1 (en) * 2008-02-15 2011-07-28 Cobian Paul J Sample acquisition device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2100157A (en) * 1937-07-09 1937-11-23 Harry H Chandler Swab
US2835246A (en) * 1954-12-22 1958-05-20 Boettger Paul Handling medical specimens
US3163160A (en) * 1962-11-15 1964-12-29 Milton J Cohen Disposable swab and culture medium device
US3308039A (en) * 1966-02-15 1967-03-07 Allergan Pharma Disposable culturing device
US3640268A (en) * 1965-10-23 1972-02-08 Hugh J Davis Method and device for biopsy specimen collecting and handling

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2100157A (en) * 1937-07-09 1937-11-23 Harry H Chandler Swab
US2835246A (en) * 1954-12-22 1958-05-20 Boettger Paul Handling medical specimens
US3163160A (en) * 1962-11-15 1964-12-29 Milton J Cohen Disposable swab and culture medium device
US3640268A (en) * 1965-10-23 1972-02-08 Hugh J Davis Method and device for biopsy specimen collecting and handling
US3308039A (en) * 1966-02-15 1967-03-07 Allergan Pharma Disposable culturing device

Cited By (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3890954A (en) * 1973-05-08 1975-06-24 U S Medical Research & Dev Inc Method of and apparatus for collecting cultures
US4409988A (en) * 1973-05-08 1983-10-18 Donald J. Greenspan Apparatus for collecting cultures
US4014746A (en) * 1973-05-08 1977-03-29 U.S. Medical Research And Development, Inc. Method of and apparatus for collecting cultures
US4184483A (en) * 1973-05-08 1980-01-22 U.S. Medical Research & Development, Inc. Method of and apparatus for collecting cultures
US3913562A (en) * 1974-01-16 1975-10-21 Moore Perk Corp Disposable package for collecting and transporting cultures for laboratory analysis
US3918435A (en) * 1974-01-24 1975-11-11 Miles Lab Transport swab tube
US4387725A (en) * 1981-02-10 1983-06-14 Mull John D Device for use in the collection and transportation of medical specimens
US4353868A (en) * 1981-05-29 1982-10-12 Sherwood Medical Industries Inc. Specimen collecting device
WO1983003047A1 (en) * 1982-03-01 1983-09-15 E & K Corp Method and apparatus for collecting and/or growing protected biological specimens
US4485824A (en) * 1982-03-01 1984-12-04 E & K Corporation Method and apparatus for collecting and/or growing protected biological specimens
EP0155747A1 (en) * 1984-03-19 1985-09-25 Kidde, Inc. Tube culture system
WO1986003395A1 (en) * 1984-12-03 1986-06-19 Accu-Med Corporation Apparatus for collecting and/or growing protected biological cultures
US4633886A (en) * 1985-05-02 1987-01-06 Bucaro Jr Russell J Device for home detection of cervical and vaginal cancer
US4637061A (en) * 1985-12-20 1987-01-13 Riese J Richard Specimen, sample collection and transport container
US4685578A (en) * 1986-09-10 1987-08-11 Minnesota Mining And Manufacturing Company Tamper indication system
US4707450A (en) * 1986-09-25 1987-11-17 Nason Frederic L Specimen collection and test unit
US4838851A (en) * 1986-11-26 1989-06-13 Shabo Alan L Applicator and package therefor
US4769333A (en) * 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4978502A (en) * 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US4859603A (en) * 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
US4978504A (en) * 1988-02-09 1990-12-18 Nason Frederic L Specimen test unit
US5078968A (en) * 1988-02-09 1992-01-07 Nason Frederic L Specimen test unit
US5238649A (en) * 1988-02-09 1993-08-24 Nason Frederic L Specimen test unit
US5266266A (en) * 1988-02-09 1993-11-30 Nason Frederic L Specimen test unit
EP0354704A1 (en) * 1988-08-01 1990-02-14 Adi Diagnostics Inc. Medical swab device
US4952204A (en) * 1988-08-10 1990-08-28 Gam-Med Packaging Corporation Dry handle swab assembly and unit
US5246856A (en) * 1989-01-26 1993-09-21 Scan-Labs Ltd. Specimen receptacles for swabbing sets
EP0572637A4 (en) * 1990-12-13 1995-08-30 Frederic L Nason Specimen test unit
EP0572637A1 (en) * 1990-12-13 1993-12-08 NASON, Frederic L. Specimen test unit
US5283038A (en) * 1990-12-18 1994-02-01 Saliva Diagnostic Systems, Inc. Fluid sampling and testing device
US5260031A (en) * 1990-12-18 1993-11-09 Saliva Diagnostic Systems, Inc. Saliva sampling device with sample adequacy indicating system
WO1995019447A1 (en) * 1994-01-14 1995-07-20 The Jockey Club Non-invasive sampling method for nucleic acid analysis
EP0734684A1 (en) * 1995-03-30 1996-10-02 Ortho Pharmaceutical Corporation In home oral fluid sample collection device and package for mailing of such device
US6423550B1 (en) 1995-03-30 2002-07-23 Ortho Pharmaceutical Corporation Home oral fluid sample collection device and package for mailing of such device
US5827675A (en) * 1995-07-12 1998-10-27 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US6180395B1 (en) * 1995-07-12 2001-01-30 Charm Sciences, Inc. Reagent chamber for test apparatus and test apparatus
US5965453A (en) * 1995-07-12 1999-10-12 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US5879635A (en) * 1997-03-31 1999-03-09 Nason; Frederic L. Reagent dispenser and related test kit for biological specimens
US5826600A (en) * 1997-09-29 1998-10-27 National Healthcare Products, Ltd. Disposable dry-handle mascara applicator assembly
US5869003A (en) * 1998-04-15 1999-02-09 Nason; Frederic L. Self contained diagnostic test unit
US6248294B1 (en) 1998-04-15 2001-06-19 Frederic L. Nason Self contained diagnostic test unit
US6010462A (en) * 1998-05-28 2000-01-04 Becton Dickinson And Company Blister style culture transport device and method for using the same
EP0960825A2 (en) 1998-05-28 1999-12-01 Becton Dickinson and Company Blister-type device for transporting biological or chemical samples
US6312395B1 (en) 1999-06-29 2001-11-06 Innovative Genetic Technology Cell collection and transport
US6516947B1 (en) 2000-08-11 2003-02-11 Viridian Packaging Solutions, Llc Containers having a fracture recess for opening the containers
WO2002085240A3 (en) * 2001-04-20 2004-03-11 3M Innovative Properties Co Container for multiple-component compositions
EP1271124A1 (en) * 2001-06-21 2003-01-02 GC Corporation Pretreatment instrument of saliva and pretreatment method of saliva
JP2003004605A (en) * 2001-06-21 2003-01-08 Gc Corp Saliva pretreatment instrument and saliva pretreatment method
US20020197738A1 (en) * 2001-06-21 2002-12-26 Gc Corporation Pretreatment instrument of saliva and pretreatment method of saliva
US7160689B2 (en) * 2001-06-21 2007-01-09 Gc Corporation Pretreatment instrument of saliva and pretreatment method of saliva
JP4642277B2 (en) * 2001-06-21 2011-03-02 株式会社ジーシー Pretreatment methods of pre-treatment equipment and saliva of saliva
US20060074347A1 (en) * 2002-10-09 2006-04-06 Sunstar Inc Sputum-collecting tool
WO2004038382A1 (en) * 2002-10-09 2004-05-06 Sunstar Inc. Sputum-collecting tool
US7264776B2 (en) * 2003-07-11 2007-09-04 Huiyan Guo Sanitary and compact fecal occult blood collector
US20050009200A1 (en) * 2003-07-11 2005-01-13 Huiyan Guo Sanitary and compact fecal occult blood collector
US6991898B2 (en) 2003-10-20 2006-01-31 Kimberly-Clark Worldwide, Inc. Diagnostic test device and method of using same
US20050084842A1 (en) * 2003-10-20 2005-04-21 O'connor Amanda L. Diagnostic test device and method of using same
US7993871B2 (en) 2004-12-22 2011-08-09 Charm Sciences, Inc. Sampling method and device
US20080206740A1 (en) * 2004-12-22 2008-08-28 Skiffington Richard T Sampling Method and Device
US7642087B2 (en) * 2005-09-27 2010-01-05 Sysmex Corporation Chromatography kit, examination container, and method for manufacturing the same
US20070178606A1 (en) * 2005-09-27 2007-08-02 Sysmex Corporation Chromatography kit, examination container, and method for manufacturing the same
US7915032B2 (en) 2006-03-03 2011-03-29 Capitol Vial Inc. Sample collection system and method
US20070208274A1 (en) * 2006-03-03 2007-09-06 Capitol Vial Inc. Sample Collection System And Method
US8476064B2 (en) 2006-05-09 2013-07-02 Charm Sciences, Inc. Inhibition assay method and device for detection of antibiotics
US20100285572A1 (en) * 2006-05-09 2010-11-11 Salter Robert S Inhibition Assay Method and Device for Detection of Antibiotics
US20100136670A1 (en) * 2007-05-04 2010-06-03 Markovsky Robert J Sampling Method and Device
US20090202393A1 (en) * 2008-02-13 2009-08-13 Capitol Vial Inc. Fluid sample collection system
US7850922B2 (en) 2008-02-13 2010-12-14 Capitol Vial Inc. Fluid sample collection system
US20090209044A1 (en) * 2008-02-13 2009-08-20 Capitol Vial Inc. Fluid Sample Collection System and Method
US7854895B2 (en) 2008-02-13 2010-12-21 Capitol Vial Inc. Fluid sample collection system and method
US20110146419A1 (en) * 2008-02-15 2011-06-23 Gonzalez Bernard A Sample acquisition device
US20110179887A1 (en) * 2008-02-15 2011-07-28 Cobian Paul J Sample acquisition device
US8677843B2 (en) 2008-02-15 2014-03-25 3M Innovative Properties Company Sample acquisition device

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