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US3752145A - Method for preventing air embolism in a syringe for angiographic power injector - Google Patents

Method for preventing air embolism in a syringe for angiographic power injector Download PDF

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Publication number
US3752145A
US3752145A US3752145DA US3752145A US 3752145 A US3752145 A US 3752145A US 3752145D A US3752145D A US 3752145DA US 3752145 A US3752145 A US 3752145A
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Prior art keywords
syringe
outlet
housing
air
head
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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R Runnells
F Longson
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MDT Corp A CORP OF
Bank of America NA
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MDT INSTRUMENT Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/504Clinical applications involving diagnosis of blood vessels, e.g. by angiography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/48Diagnostic techniques
    • A61B6/481Diagnostic techniques involving the use of contrast agents

Abstract

A power injector or syringe designed for use in angiographic studies having a cylindrical, hollow housing and a plunger or piston fitted for reciprocating action within the housing. The housing is provided with a transparent, magnifying conical-shaped head for more easily detecting air bubbles entrained in a liquid contained by the syringe. Detection of these bubbles prior to injection minimizes the chances of air embolism during intravenous injections.

Description

United States Patent Runnells et a].

METHOD FOR PREVENTING AIR EMBOLISM IN A SYRINGE FOR ANGIOGRAPHIC POWER INJECTOR Inventors: Robert R. Runnells, Fruit Heights;

Frank W. Longson, Salt Lake City, both of Utah MDT Instrument Company, Salt Lake City, Utah Filed: Nov. 1, 1971 Appl. No.: 194,747

Assignee:

US. Cl. 128/2 R, 128/218 C, l28/2.05 R Int. Cl. A6lb 5/02, A6lm 5/18 FieldofSearch 128/218 R,2l8 C, l28/22l, 2l8 N, 2 R, 215, 216, 214 C, 218 A, 2.05 R, 2.05 F, 2 S

References Cited UNITED STATES PATENTS [/1972 Hobbs 128/218 A Aug. 14, 1973 3,349,767 l0/l967 Gidlund 128/218 R 3,030,954 4/1962 Thornton, Jr... 128/214 C 2,586,581 2/1952 Tschischeck 128/218 C X Primary Examiner-Richard A. Gaudet Assistant Examiner-J. C. McGowan Attorney-David V. Trask et al.

A power injector or syringe designed for use in angiographic studies having a cylindrical, hollow housing and a plunger or piston fitted for reciprocating action within the housing. The housing is provided with a transparent, magnifying conical-shaped head for more easily detecting air bubbles entrained in a liquid contained by the syringe. Detection of these bubbles prior to injection minimizes the chances of air embolism during intravenous injections.

ABSTRACT 3 Claims, 1 Drawing Figure Pmzmuwm 3.752.145

INVENTOR. Robert R. Runnells BY- rank W. Longson Their Horney METHOD FOR PREVENTING AIR EMBOLISM IN A SYRINGE FOR ANGIOGRAPHIC POWER INJECTOR Background of the Invention 1. Field This invention relates to a liquid injector, and particularly to a power syringe or injector designed for use in angiographic studies.

2. State of the Art Angiography is generally defined as the visual roent-. genological study of blood vessels. As the definition implies, a dye or contrast fluid is continuously injected into an artery or vein until the fluid is distributed throughout the vascular system. X-rays are then taken, permitting the vascular system (because of the opaque quality of the dye) to be clearly outlined. Defects, constrictions, etc. of the vascular system can thereby be easily detected. The inadvertent introduction of air during transportation of the contrast fluid into the vascular system can result in air embolism.

Power injectors are commonly used in angiographic studies. Normally, such an injector includes a syringe with a cylindrical hollow housing having an outlet at one end and a piston or plunger mounted slidably within the housing and capable of removal from the end of the housing opposite the outlet. Contrast fluid is poured into the syringe housing opening with the plunger removed. The plunger is controllably moved within the housing by a power means, typically, a hydraulic drive mechanism. The housing and power means are usually held in predetermined stationary position by an adjustable support means (the syringe arm housing" of the injector). A catheter is conventionally connected to the syringe housings outlet, and a contrast fluid is forced through the catheter into a vascular system. I-Ieretofore, angiographic techniques relying upon power injectors have exposed the patient to an undesirably high risk of air embolism, because of the difficulty of determining whether air is entrapped within the syringe.

Summary of the Invention The present invention provides an improved angiographic syringe specifically adapted for use in conventional angiographic power injectors. The syringe of this invention comprises a special magnifying head at the outlet end of the syringe housing which facilitates the discovery of entrapped air. The head is also specially contoured within to provide a safety chamber which, in cooperation with stop means, prevents the expulsion of a certain quantity of the contrast fluid from the syringe.

Brief Description of the Drawings The drawing, which illustrates what is presently regarded as the best mode for carrying out the invention, is a perspective view of the angiographic syringe of this invention with sections cut away for clarification.

Description of the Illustrated Embodiment The syringe of this invention includes a cylindrical, hollow housing 12 and a plunger or piston plate 14 match-fitted within the housing for slidable action. By providing an outside wall diameter of the piston plate 14 fractionally smaller than the inner wall diameter of the cylindrical housing 12, substantially no liquid escapes from between the walls under normal use. However, to insure a tight circumferential fit between the inner wall of the housing and the outer wall of the plunger (yet not overly restricting reciprocating action of the plunger), O-rings 16 are inserted into grooves 18 cut along the outer wall of the plunger. The sealing action of these O-rings insures a tight fit against the inner wall of the housing, particularly if the inner housing wall happens to be irregular.

A threaded shaft 20 is attached to the piston plate 14 and extends up beyond the cylindrical housing 12, even when fully advanced toward the outlet 22 of the housing 12. The shaft 20 may be either permanently or detachably fastened to the piston plate 14. As shown, one end 20a of the shaft 20 is screwed into a corresponding threaded central opening 24 of the piston plate 14. The

other end 20b of the shaft 20 may be connected to the drive mechanism of a power injector by any suitable means (not shown). The central portion 20c of the shaft 20 engages a threaded cental opening 30 of a circular stop plate 32 having a diameter larger than the inner diameter of the syringe housing 12. The stop plate 32 may be positioned at any desired location along the shaft 20 to check the advance of the piston plate 14 (by contact with the upper edge 34 of the syringe housing 12) as the shaft 20 is pushed down through the syringe housing 12. In this fashion, a predetermined quantity of contrast fluid, as selected by proper positioning of the stop plate, but no more, is injected into the vascular system of the patient.

In most angiographic studies the amount and rate of fluid introduced into the vascular system by the syringe must be carefully controlled. The upper portion 36 of the syringe housing 12 is threaded for mounting within the syringe arm housing (not shown) of conventional power injectors. When so mounted, the upper end 20b of shaft 20 is connected as described hereinbefore to a drive system capable of moving the shaft and piston plate 14 through the housing at a preselected controlled speed, thereby insuring a constant and continuous flow of a contrast fluid from the syringe into the vascular system.

At the outlet end of the syringe housing 12 is a novel syringe head 40 manufactured from a transparent material which is molded and/or machined to achieve magnification sufficient to facilitate viewing of the fluid contained therewithin. The syringe head 40 is preferably conically shaped-that is, the walls 42 of the syringe head converge in and down toward a centraly located outlet 22. A catheter (not shown) may be connected to the outlet 22 by means of a coupling means, such as the luer lock catheter coupling 44 illustrated, for carrying fluid from the syringe and into the vascular system.

The interior 46 of the magnifying head 40 provides a safety chamber which captures and retains a residual portion of the contrast dye or other fluid even when the piston plate 14 is fully advanced toward the outlet 22. Further advance of the piston plate 14 is checked by a stop surface 48 defined in part by the upper edge 40a of the head 40. It is thus physically impossible to expel all of the fluid contained by the syringe housing 12 through the outlet 22 by merely advancing the piston plate 14. This feature, together with the magnification provided by the head 40, makes it possible to virtually assure that no air will be injected into a patient from the claimed syringe.

The procedure normally followed in using the claimed syringe is to first position the syringe housing with the outlet end up and the magnification head 40 removed. Contrast solution is poured into the syringe housing and the head 40 is replaced. A tube is then attached to the outlet 22 of the syringe and the free end of the tube is submerged in contrast solution. Air is bled from the syringe by advancing the piston plate 14 toward the outlet 22. Additional contrast solution may then be drawn through the tube into the syringe housing by retracting the piston plate. The contents of the safety chamber 46 may then be viewed through the transparent wall 42 of the magnifying safety head. If bubbles are noted, the piston plate is advanced and retracted once more to expel the entrapped air and to replace the desired volume of contrast solution. The contents of the safety chamber are again viewed, and the piston plate may again be advanced and retracted as often as necessary until no bubbles are observed through the magnifying walls 42 of the head 40.

Sometimes it is convenient to eliminate the step of filling the syringe housing through the tip end, but in any event, the presence of entrapped air is determined by visual observation with the magnifying head up and the syringe as nearly vertical as possible, and after all observed air is expelled, injections should be given with the outlet down and the syringe as nearly vertical as the angiographic procedure permits.

The piston plate is advanced in accordance with the program of the angiographic procedure, but the piston plate can never advance beyond the stop surface 48 of the magnifying head 40. Any entrapped air will tend to rise in the contrast solution toward the piston plate. Accordingly, it will be retained within the safety chamber 46.

Although in most cases the housing is constructed from a metal such as stainless steel, durable plastic may also be used. The syringe head, although normally totally transparent, may be constructed from an opaque material such as plastic or metal and magnifying windows inserted into the head to permit internal viewing.

For most angiographic work the solution introduced into the patient should be maintained at a controlled temperature, e.g., a temperature approaching body temperature. The claimed syringe is compatible with the heating jackets (not shown) contained within the syringe arm housings of available power injectors, but it is within contemplation that heating coils may be provided in the syringe housing 12 if desired.

The syringe head 40 is transparent and capable of magnification, but it must also have high resistance to breakage and be resistant to the conditions normally encountered in sterilization procedures. The magnifying power of the head should be substantially greater than is provided by the glass walls of a conventional medical syringe, for example. Thus, the surfaces of the walls 42 should be contoured to increase the magnification provided by the shape of a conventional syringe tip. Transparent polycarbonate resin, such as that marketed by the General Electric Company under the Trademark LEXAN," is the presently preferred material of construction, but certain other plastic and resin materials have suitable properties for use.

Reference herein to details of the illustrated embodiment is not intended to restrict the scope of the claims which themselves recite the features regarded as essential to the invention.

We claim:

1. In angiography wherein contrast solution is poured into the housing of a power injector syringe and thereafter expelled at a controlled rate by power means advancing the plunger of said syringe towards the outlet thereof, the improvement for eliminating the hazard of air embolism resulting from expelling entrapped air from said syringe into the vascular system of a patient comprising:

providing the outlet of said syringe in a removable,

transparent, magnifying head;

providing in said head adjacent said outlet, a safety chamber configurated such that the plunger of the syringe cannot be advanced thereinto;

filling said syringe with contrast solution;

orienting the syringe with the outlet end up, thereby permitting any entrapped air to rise towards the outlet;

viewing the contents of said safety chamber through the transparent walls of said magnifying head to determine whether bubbles of entrapped air are present in said chamber; advancing said plunger towards said outlet to expel any entrapped air from said safety chamber by displacement while said outlet end is oriented up;

orienting said outlet end down, thereby to permit any remaining entrapped air to rise through said contrast solution away from said outlet; and

injecting said contrast solution in accordance with the program of an angiographic procedure with said outlet end pointing down and said syringe as nearly vertical as the angiographic procedure permits.

2. The improvement of claim 1 wherein the contrast solution is poured into said syringe from the outlet end with the said magnifying head removed.

3. The improvement of claim 1 including attaching a tube to said outlet;

submerging the free end of said tube in a pool of contrast solution afer contrast solution is poured into said syringe;

expelling entrapped air through said tube by advancing the plunger towards said outlet;

drawing additional contrast solution into said syringe from said pool through said tube; and

viewing the contents of said safety chamber through the transparent walls of said magnifying head to determine whether bubbles of entrapped air remain in said chamber.

i k 8 t

Claims (3)

1. In angiography wherein contrast solution is poured into the housing of a power injector syringe and thereafter expelled at a controlled rate by power means advancing the plunger of said syringe towards the outlet thereof, the improvement for eliminating the hazard of air embolism resulting from expelling entrapped air from said syringe into the vascular system of a patient comprising: providing the outlet of said syringe in a removable, transparent, magnifying head; providing in said head adjacent said outlet, a safety chamber configurated such that the plunger of the syringe cannot be advanced thereinto; filling said syringe with contrast solution; orienting the syringe with the outlet end up, thereby permitting any enTrapped air to rise towards the outlet; viewing the contents of said safety chamber through the transparent walls of said magnifying head to determine whether bubbles of entrapped air are present in said chamber; advancing said plunger towards said outlet to expel any entrapped air from said safety chamber by displacement while said outlet end is oriented up; orienting said outlet end down, thereby to permit any remaining entrapped air to rise through said contrast solution away from said outlet; and injecting said contrast solution in accordance with the program of an angiographic procedure with said outlet end pointing down and said syringe as nearly vertical as the angiographic procedure permits.
2. The improvement of claim 1 wherein the contrast solution is poured into said syringe from the outlet end with the said magnifying head removed.
3. The improvement of claim 1 including attaching a tube to said outlet; submerging the free end of said tube in a pool of contrast solution afer contrast solution is poured into said syringe; expelling entrapped air through said tube by advancing the plunger towards said outlet; drawing additional contrast solution into said syringe from said pool through said tube; and viewing the contents of said safety chamber through the transparent walls of said magnifying head to determine whether bubbles of entrapped air remain in said chamber.
US3752145A 1971-11-01 1971-11-01 Method for preventing air embolism in a syringe for angiographic power injector Expired - Lifetime US3752145A (en)

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Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993061A (en) * 1975-02-28 1976-11-23 Ivac Corporation Syringe pump drive system and disposable syringe cartridge
US5300031A (en) * 1991-06-07 1994-04-05 Liebel-Flarsheim Company Apparatus for injecting fluid into animals and disposable front loadable syringe therefor
US5385558A (en) * 1993-09-03 1995-01-31 Maxxim Medical, Inc. Angiographic control syringe
US5855568A (en) * 1996-11-22 1999-01-05 Liebel-Flarsheim Company Angiographic syringe and luer connector
US5868710A (en) * 1996-11-22 1999-02-09 Liebel Flarsheim Company Medical fluid injector
US6652489B2 (en) * 2000-02-07 2003-11-25 Medrad, Inc. Front-loading medical injector and syringes, syringe interfaces, syringe adapters and syringe plungers for use therewith
US20040064041A1 (en) * 2002-05-30 2004-04-01 Lazzaro Frank A. Front-loading medical injector and syringes, syringe interfaces, syringe adapters and syringe plungers for use therewith
US6733478B2 (en) 1992-08-17 2004-05-11 Medrad, Inc. System and method for providing information from a syringe to an injector
US6808513B2 (en) 1992-08-17 2004-10-26 Medrad, Inc. Front loading medical injector and syringe for use therewith
US6958053B1 (en) 1999-11-24 2005-10-25 Medrad, Inc. Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector
US7008535B1 (en) 2000-08-04 2006-03-07 Wayne State University Apparatus for oxygenating wastewater
US7419478B1 (en) 2003-06-25 2008-09-02 Medrad, Inc. Front-loading syringe for medical injector having a flexible syringe retaining ring
US20130204130A1 (en) * 2012-02-03 2013-08-08 Merit Medical Systems, Inc. Devices, systems and methods for carbon dioxide angiography
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9173995B1 (en) 2014-10-28 2015-11-03 Bayer Healthcare Llc Self-orienting syringe and syringe interface
US9199033B1 (en) 2014-10-28 2015-12-01 Bayer Healthcare Llc Self-orienting syringe and syringe interface
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector
US9694131B2 (en) 2003-11-25 2017-07-04 Bayer Healthcare Llc Medical injector system
US9744305B2 (en) 2012-09-28 2017-08-29 Bayer Healthcare Llc Quick release plunger
US9844622B2 (en) 2000-07-10 2017-12-19 Bayer Healthcare Llc Syringes for medical injector systems
US9855390B2 (en) 2006-03-15 2018-01-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes

Cited By (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993061A (en) * 1975-02-28 1976-11-23 Ivac Corporation Syringe pump drive system and disposable syringe cartridge
US6659979B2 (en) 1991-06-07 2003-12-09 Liebel Flarsheim Company Method of injecting fluid into animals
US5738659A (en) * 1991-06-07 1998-04-14 Liebel-Flarsheim Company Method of injecting fluid into animals
US5451211A (en) * 1991-06-07 1995-09-19 Liebel-Flarsheim Company Disposable front loadable syringe for power injector for injecting fluid into animals
US5456669A (en) * 1991-06-07 1995-10-10 Liebel-Flarsheim Company Method of front loading an injector and injecting fluid into animals therewith
US5456670A (en) * 1991-06-07 1995-10-10 Liebel-Flarsheim Company Power injector for injecting fluid into animals
US5300031A (en) * 1991-06-07 1994-04-05 Liebel-Flarsheim Company Apparatus for injecting fluid into animals and disposable front loadable syringe therefor
US7081104B2 (en) 1991-06-07 2006-07-25 Liebel-Flarsheim Company Method and apparatus for injecting fluid into animals and disposable front loadable syringe therefor
US20040122371A1 (en) * 1991-06-07 2004-06-24 Liebel-Flarsheim Company Method and apparatus for injecting fluid into animals and disposable front loadable syringe therefor
US20060264744A1 (en) * 1991-06-07 2006-11-23 Liebel-Flarsheim Company Method and Apparatus for Injecting Fluid into Animals and Disposable Front Loadable Syringe Therefor
US6808513B2 (en) 1992-08-17 2004-10-26 Medrad, Inc. Front loading medical injector and syringe for use therewith
US6733478B2 (en) 1992-08-17 2004-05-11 Medrad, Inc. System and method for providing information from a syringe to an injector
US7081105B2 (en) 1992-08-17 2006-07-25 Medrad, Inc. Injector system having a front loading pressure jacket assembly
US20050059932A1 (en) * 1992-08-17 2005-03-17 Reilly David M. Injector system having a front loading pressure jacket assembly
US5385558A (en) * 1993-09-03 1995-01-31 Maxxim Medical, Inc. Angiographic control syringe
US6254572B1 (en) 1996-11-22 2001-07-03 Liebel Flarsheim Company Medical fluid injector having watchdog circuit
US6004292A (en) * 1996-11-22 1999-12-21 Liebel Flarsheim Company Medical fluid injector
US5868710A (en) * 1996-11-22 1999-02-09 Liebel Flarsheim Company Medical fluid injector
US5855568A (en) * 1996-11-22 1999-01-05 Liebel-Flarsheim Company Angiographic syringe and luer connector
US6159183A (en) * 1996-11-22 2000-12-12 Liebel Flarsheim Company Medical fluid injector having face plate with magnetic conductors
US6958053B1 (en) 1999-11-24 2005-10-25 Medrad, Inc. Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector
US9636452B2 (en) 2000-02-07 2017-05-02 Bayer Healthcare Llc Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US20040133183A1 (en) * 2000-02-07 2004-07-08 Mark Trocki Method of preparing for a fluid injection procedure using a medical injector and a syringe
US20040133161A1 (en) * 2000-02-07 2004-07-08 Mark Trocki Front-loading syringe adapted to releasably engage a medical injector regardless of the orientation of the syringe with respect to the injector
US20040133162A1 (en) * 2000-02-07 2004-07-08 Mark Trocki Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US20040133153A1 (en) * 2000-02-07 2004-07-08 Mark Trocki Syringe adapter for use with a medical injector and method for adapting an injector
US6652489B2 (en) * 2000-02-07 2003-11-25 Medrad, Inc. Front-loading medical injector and syringes, syringe interfaces, syringe adapters and syringe plungers for use therewith
US8721596B2 (en) 2000-02-07 2014-05-13 Bayer Medical Care Inc. Front-loading syringe adapted to releasably engage a medical injector regardless of the orientation of the syringe with respect to the injector
US7540856B2 (en) 2000-02-07 2009-06-02 Medrad, Inc. Front-loading medical injector adapted to releasably engage a syringe regardless of the orientation of the syringe with respect to the injector
US9844622B2 (en) 2000-07-10 2017-12-19 Bayer Healthcare Llc Syringes for medical injector systems
US7008535B1 (en) 2000-08-04 2006-03-07 Wayne State University Apparatus for oxygenating wastewater
US7294278B2 (en) 2000-08-04 2007-11-13 Wayne State University Method for oxygenating wastewater
US8133203B2 (en) 2002-05-30 2012-03-13 Medrad, Inc. Method of injecting fluids from a dual syringe injector system
US8574200B2 (en) 2002-05-30 2013-11-05 Medrad, Inc. Dual syringe injector system
US20040064041A1 (en) * 2002-05-30 2004-04-01 Lazzaro Frank A. Front-loading medical injector and syringes, syringe interfaces, syringe adapters and syringe plungers for use therewith
US7553294B2 (en) 2002-05-30 2009-06-30 Medrad, Inc. Syringe plunger sensing mechanism for a medical injector
US7419478B1 (en) 2003-06-25 2008-09-02 Medrad, Inc. Front-loading syringe for medical injector having a flexible syringe retaining ring
US9694131B2 (en) 2003-11-25 2017-07-04 Bayer Healthcare Llc Medical injector system
US9855390B2 (en) 2006-03-15 2018-01-02 Bayer Healthcare Llc Plunger covers and plungers for use in syringes
US9463335B2 (en) 2010-06-04 2016-10-11 Bayer Healthcare Llc System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9265877B2 (en) * 2012-02-03 2016-02-23 Merit Medical Systems, Inc. Devices, systems and methods for carbon dioxide angiography
US20130204130A1 (en) * 2012-02-03 2013-08-08 Merit Medical Systems, Inc. Devices, systems and methods for carbon dioxide angiography
US9744305B2 (en) 2012-09-28 2017-08-29 Bayer Healthcare Llc Quick release plunger
US9173995B1 (en) 2014-10-28 2015-11-03 Bayer Healthcare Llc Self-orienting syringe and syringe interface
US9700670B2 (en) 2014-10-28 2017-07-11 Bayer Healthcare Llc Self-orienting syringe and syringe interface
US9199033B1 (en) 2014-10-28 2015-12-01 Bayer Healthcare Llc Self-orienting syringe and syringe interface
US9480797B1 (en) 2015-10-28 2016-11-01 Bayer Healthcare Llc System and method for syringe plunger engagement with an injector

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