US3705582A - Breech loaded syringe and method of breech loading same - Google Patents
Breech loaded syringe and method of breech loading same Download PDFInfo
- Publication number
- US3705582A US3705582A US860223A US3705582DA US3705582A US 3705582 A US3705582 A US 3705582A US 860223 A US860223 A US 860223A US 3705582D A US3705582D A US 3705582DA US 3705582 A US3705582 A US 3705582A
- Authority
- US
- United States
- Prior art keywords
- piston
- barrel
- chamber
- syringe
- inner end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title claims description 15
- 239000012530 fluid Substances 0.000 claims abstract description 51
- 239000007788 liquid Substances 0.000 claims abstract description 36
- 239000003814 drug Substances 0.000 claims abstract description 33
- 238000003780 insertion Methods 0.000 claims abstract description 12
- 230000037431 insertion Effects 0.000 claims abstract description 12
- 238000007789 sealing Methods 0.000 claims description 17
- 238000013022 venting Methods 0.000 claims description 13
- 210000003813 thumb Anatomy 0.000 description 7
- 229940071643 prefilled syringe Drugs 0.000 description 4
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 210000003811 finger Anatomy 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- POIUWJQBRNEFGX-XAMSXPGMSA-N cathelicidin Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C1=CC=CC=C1 POIUWJQBRNEFGX-XAMSXPGMSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001084 poly(chloroprene) Polymers 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
Definitions
- a control is provided for selectively deforming the piston to permit the barrel to be preloaded with the liquid medicament through the breech end thereof with the piston being brought into engagement with the liquid while a fluid bypass passage is provided around the piston to the breech end of the barrel, thereby to vent air outwardly from the space between the piston and the liquid medicament during the insertion of the piston.
- This invention relates to syringes and in particular to piston-type syringes.
- the present invention comprehends an improved syringe structure wherein the piston, during insertion through the breech end of the barrel into engagement with the previously deposited liquid medicament, is deformed so as to provide a bypass vent.
- the deforming means may comprise a tubular element adapted to receive the piston under compression and having a clearance with the barrel permitting movement of the inner end of the element through the breech end of the barrel into juxtaposition with the liquid medicament wherein the trapped air is vented through the clearance space between the sleeve and the barrel.
- the piston Upon reaching the fully inserted position, the piston is removed from its position within the sleeve end thereby permitting the, piston to expand into sealed sliding engagement with the barrel wall.
- the piston may be carried on the inner end of a shaft extending from the piston to outwardly of the barrel outer end.
- the shaft extends coaxially through a tubular sleeve having a bore radially enlarged at its inner end to define a piston receiving recess.
- the tubular sleeve also has a recess at its outer end for receiving in nested relationship the thumb piece of the shaft. Movement between the shaft and the sleeve may be effected manually to provide the selective deformation and release of the piston.
- the piston may be deformed by a rib element on the inner end of the sleeve which extends the length of the piston to deform an outer wall portion thereof radially inwardly and thereby form a fluid bypass passage permitting the air to be vented from the barrel during the insertion of the piston.
- a plurality of such rib elements may be provided to form a plurality of such bypass passages for venting during the piston insertion step.
- the filling of the syringe may be effected to provide a prefilled syringe unit which may be stored for subsequent use as desired. In such case, the needle end of the syringe is maintained sealingly closed. Alternatively, the syringe will be breech filled at the time of use by the above indicated steps.
- FIG. 1 is a fragmentary enlarged front view of a syringe embodying the invention with portions broken away to illustrate the invention
- FIG. 2 is a view similar to that of FIG. 1 but illustrating the arrangement of the syringe during the piston inserting operation;
- FIG. 3 is an exploded view with portions broken away illustrating the arrangement of the piston and sleeve assembly prior to insertion into the syringe barrel;
- FIG. 4 is a front view of one form of sleeve thereof
- FIG. 5 is a fragmentary bottom end view thereof
- FIG. 6 is a front view of the sleeve used in the syringe shown in FIGS. 1-3, with a portion broken away to pro vide a clear illustration of the invention
- FIG. 7. is a bottom end view of the sleeve of FIG. 6;
- FIG. 8 is a front view of still another modified form of sleeve thereof with a portion broken away to illus trate the invention.
- FIG. 9 is a bottom end view of the sleeve of FIG. 8.
- a syringe generally designated 10 is shown as having a conventional tubular barrel 1 l defining a chamber l2v opening axially outwardly through an outer end 13.
- the inner end 14 of the barrel 1] is provided with an outlet 15 opening into a connector 16 for attaching a needle, such as conventional needle 17, in fluid transfer association with the inner end of the barrel.
- the connector comprises a conventional luer lock connector, it being understood that any suitable needle connecting means may be utilized.
- connector 16 Prior to the installation of the needle 17 onto the connector 16, connector 16 may be conventionally closed by a conventional cap 18, as shown in FIGS. 2 and 3.
- the syringe 10 may comprise a prefilled syringe wherein a body of liquid, such as liquid medicament 19, is provided in the portion 20 of the chamber 12 inwardly of a piston 21.
- a body of liquid such as liquid medicament 19
- the liquid 19 is delivered into the chamber 12 through the outer end 13 in a breech loading operation.
- Inuun npiston 21 is then brought into the chamber 12 through the outer end 13 to engage the liquid 19 as shown in FIG. 2.
- a bypass passage 22 is provided around the piston from the inner chamber portion 20 to the outer opening 13 whereby air may be vented from the chamber 12 as the piston is moved downwardly therethrough to the position of FIG. 2.
- the invention comprehends the provision of the vent passage 22 by means of a tubular element, or sleeve, 23 having an outside diameter slightly smaller than the inside diameter of the barrel 11.
- the bore 24 of sleeve 23 is stepped at 25 to define a radially enlarged inner end bore portion 26 adapted to receive the piston 21 as shown in FIG. 2.
- Piston 21 is preferably formed of a resilient material, such as neoprene rubber, to permit the ready compression thereof into the bore portion 26 of the sleeve 23 as by urging the sleeve axially forward relative to the piston 21 until the piston is encased in portion 26 as shown in FIG. 3.
- the piston is secured to an end connector portion 27 of a shaft 28 having an outer thumb piece 29.
- Shaft 28 extends coaxially through the bore 24 of sleeve 23. As shown in FIG. 2, shaft 28 is somewhat smaller in transverse dimension than the diameter of bore 24, permitting the ready axial movement of the shaft 28 therethrough when desired.
- the outer end of the sleeve is provided with a flange 30. Flange 30 is spaced outwardly of the conventional outturned flange 31 of the barrel to permit the user to insert his fingers under flange 30 with his thumb on thumb piece 29 and thereby readily effect a movement of the piston 21 inwardly from the end portion 26 when desired.
- the flange 30 of the sleeve 23 has a recess formed in the upper surface 32 which recess 35 is of a size and shape to receive in nested relationship the thumb piece 29 of the shaft 28 when the shaft is fully depressed relative to the sleeve 23.
- the thumb piece 29 will nest in the recess 35 and create the appearance of a one piece plunger unit.
- the piston 21 may be provided retracted within bore portion 26 as shown in FIG. 3, permitting the movement of the assembled piston and sleeve 23 into the barrel 11 as discussed above.
- the piston may be mounted on the shaft end 27 inwardly of the sleeve (in the arrangement seen in FIG. 1) and inserted into the open end 13 of the barrel 11. The piston is then caused to move into the bore portion 26 by a combination of forces directed by the users fingers on the outer surface 32 of the flange 30 and the fluid pressure within the bore 12 ahead of the piston 21 thereby to cause the piston to move axially into the sleeve bore end 2 6.
- the piston is deformed to provide a vent passage around the piston 21 by effecting relative movement between the shaft with the piston connected thereto, and the sleeve.
- such relative movement positions the piston 21 in the sleeve bore end 26 and this effects deformation of the piston by urging peripheral portions thereof radially inwardly, the piston being retained in the bore end 26 by the inherent resiliency thereof.
- the syringe 10 provides an improved structure permitting prefilling of the syringe in an aseptic manner by a breech loading of the liquid medicament therein.
- the liquid medicament may be retained in the prefilled syringe by the subsequent installation of the piston 21 as discussed above, whereby the piston may be brought into engagement with the upper surface of the liquid by a vented movement of the piston through the barrel, thereby maintaining the aseptic condition of the breech loaded syringe.
- the cap 18 is removed and the needle 17 installed on the connector 16 in the conventional manner whereupon the liquid medicament may be delivered through the needle by suitable manipulation of the shaft 28 by the users fingers engaging flange 31 and thumb piece 29.
- the invention comprehends broadly providing a means for deforming the piston 21 during its insertion through the bore 12 to define a bypass passage 22 whereby the bore '12 is vented to facilitate the movement of the piston fully to the position of FIG. 2.
- the means for forming the bypass passage 22 may comprise means for receiving the piston under compression within one end of the tubular sleeve 23.
- the sleeve construction is illustrated in FIGS. 6 and 7.
- other forms of piston deforming means may be provided within the scope of the invention. Illustratively, in FIG.
- a sleeve 123 is shown to comprise a sleeve similar to sleeve 23 but having a plurality of circumferentially spaced end prongs 133 which effectively distort the piston when the piston is retracted into the space 126 radially within the prongs.
- three such prongs are provided spaced about the axis of the sleeve.
- a further modified form of sleeve 223 is shown to comprise a sleeve having a depending prong 223 provided with a radially inwardly projecting rib 234 which effectively distorts the piston to define an air bypass vent passage for venting the barrel during the installation of the piston.
- each of the sleeves 23, 123, and 223 is similar to the others and functions in a similar manner except as otherwise noted.
- means are provided for deforming the piston during insertion thereof into the barrel bore to define a vent passage.
- the deforming means are carried on an elongated element which extends to outwardly of the barrel serving as a means for effecting a separation of the deforming 'means from the piston after the piston reaches the desired fully inserted position whereby the piston may then function in the normal manner within the barrel.
- the element carrying the deforming means may have other configurations in addition to the tubular sleeve configuration of the illustrative embodiments.
- the different parts of these syringes may be made of suitable materials, such as plastics, permitting relative ease of sterilization.
- the syringes may comprise one-time use, prefilled syringes.
- a resilient piston arranged to have sealing sliding engagement with the barrel in said chamber; first means secured to said piston and extending from said piston to outwardly of said outer end for moving said piston into said chamber through said outer end during insertion thereof in said barrel and for moving said piston to discharge fluid from said chamber in response to a manually applied force on said first means during operational use of the syringe; and second means carried by said first means and extending from within said chamber to outwardly of said outer end, said second means being movable in one direction relative to said first means to deform said piston for forming fluid bypass means around said piston for venting the chamber portion forward of said piston, and movable in the direction opposite said one direction relative to said first means for removing the fluid bypass means whereby the piston sealingly engages with the barrel to force fluid from said chamber through said needle connecting portion as an incident of movement of said piston in said chamber toward said inner end in response to said applied force on said first means.
- a syringe having a tubular barrel defining a chamber opening axially through the outer end of the barrel, and a needle connecting portion at the inner end of the barrel for connecting a needle in fluid flow association with said chamber, the improvement comprising:
- a resilient piston arranged to have sealing sliding engagement with the barrel in said chamber
- first and second means carried by said first means, said first and second means being relatively movable a. for forming fluid bypass means around said piston for venting the chamber portion forward of said piston, and
- said second means comprising means having a tubular inner end removably receiving said piston, and means for causing axial removal of said piston from said tubular inner end, said second means having a clearance with said barrel defining said fluid bypass means to said outer end of the barrel, said second means also having an axially inner end for retaining the piston axially inwardly of said tubular end subsequent to said removal.
- a syringe having a tubular barrel defining a chamber opening axially through the outer end of the barrel, and a needle connecting portion at the inner end of the barrel for connecting a needle in fluid flow association with said chamber, the improvement comprising:
- a resilient piston arranged to have sealing sliding engagement with the barrel in said chamber
- first and second means carried by said first means and extending from within said chamber to outwardly of said outer end, said first and second means being selectively relatively movable.
- said second means comprising means removably extending the length of said piston between said piston and said barrel for deforming said piston to form a plurality of fluid bypass passages between the deformed piston and the barrel which communicate with said outer end of the barrel, said passages defining said fluid bypass means, said second means comprising a plurality of angularly spaced elements providing said fluid bypass means.
- a syringe having a tubular barrel defining a chamber opening axially through the outer end of the barrel, and a needle connecting portion at the inner end of the barrel for connecting a needle in fluid flow association with said chamber, the improvement comprising:
- a resilient piston arranged to have sealing sliding engagement with the barrel in said chamber
- first means extending from said piston to outwardly of said outer end for manipulating said piston during operational use of the syringe
- first and second means carried by said first means and extending from within said chamber to outwardly of said outer end, said first and second means being selectively relatively movable a. for forming fluid bypass means around said piston for venting the chamber portion forward of said piston, and b. for removing the fluid bypass means whereby the piston is in sealing engagement with the barrel to force fluid from said chamber through said needle connecting portion as an incident of movement of said piston in said chamber toward said inner end, said second means comprising a tubular element having an axial bore provided with a portion at the inner end of said tubular element of greater diameter than other portions of said bore for receiving said piston, said tubular element removably extending the length of said piston between the piston and said barrel for deforming the piston to define said fluid bypass means between the deformed piston and the barrel which communicate with said outer end of the barrel.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86022369A | 1969-09-23 | 1969-09-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3705582A true US3705582A (en) | 1972-12-12 |
Family
ID=25332754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US860223A Expired - Lifetime US3705582A (en) | 1969-09-23 | 1969-09-23 | Breech loaded syringe and method of breech loading same |
Country Status (5)
Country | Link |
---|---|
US (1) | US3705582A (hu) |
BE (1) | BE756550A (hu) |
DE (1) | DE2046953A1 (hu) |
GB (1) | GB1304224A (hu) |
SE (1) | SE363238B (hu) |
Cited By (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3824708A (en) * | 1972-12-26 | 1974-07-23 | Xerox Corp | Educational device |
US3824711A (en) * | 1972-12-26 | 1974-07-23 | Xerox Corp | Educational device |
US3885710A (en) * | 1973-03-20 | 1975-05-27 | Cohen Milton | Mixing dispenser with a selectively retractable seal to permit intermixing of the ingredients |
US3910273A (en) * | 1973-03-08 | 1975-10-07 | Sven Arlers | Aspirating hypodermic syringe |
US4188949A (en) * | 1977-07-05 | 1980-02-19 | Becton, Dickinson & Company | Sequential injection syringe |
US4950243A (en) * | 1987-11-27 | 1990-08-21 | Estruch Miracle C | Syringe for one sole use |
US5009646A (en) * | 1988-03-16 | 1991-04-23 | Daikyo Gomu Seiko Ltd. | Sliding stopper for a syringe |
US5207983A (en) * | 1992-01-29 | 1993-05-04 | Sterling Winthrop Inc. | Method of terminal steam sterilization |
US5256154A (en) * | 1992-01-31 | 1993-10-26 | Sterling Winthrop, Inc. | Pre-filled plastic syringes and containers and method of terminal sterilization thereof |
US5314415A (en) * | 1993-07-21 | 1994-05-24 | Sterling Winthrop Inc. | Aspirating plunger for power injector cartridges |
US5411488A (en) * | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having an improved plunger and plunger rod for reducing syringing force |
US5411489A (en) * | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having actuating cylinder/plunger rod combination for reducing syringing force |
US5413563A (en) * | 1994-05-06 | 1995-05-09 | Sterling Winthrop Inc. | Pre-filled syringe having a plunger, plunger insert and plunger rod |
USD383205S (en) * | 1994-05-06 | 1997-09-02 | Sterling Winthrop Inc. | Combined syringe and plunger |
US5873861A (en) * | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
US5944694A (en) * | 1996-11-12 | 1999-08-31 | Medrad, Inc. | Prefillable syringes and injectors for use therewith |
US5947935A (en) * | 1996-11-12 | 1999-09-07 | Medrad, Inc. | Syringes, syringe plungers and injector systems |
US6395007B1 (en) * | 1999-03-16 | 2002-05-28 | American Osteomedix, Inc. | Apparatus and method for fixation of osteoporotic bone |
FR2847883A1 (fr) * | 2002-11-29 | 2004-06-04 | Valois Sas | Systeme et procede de bouchage d'un reservoir et distributeur de produit fluide incorporant un tel systeme |
US6984222B1 (en) | 1996-11-12 | 2006-01-10 | Medrad, Inc. | Plunger systems |
US20060178631A1 (en) * | 2004-12-09 | 2006-08-10 | Pharma-Pen Holdings, Inc. | Automatic injection and retraction syringe |
US20070078394A1 (en) * | 2000-05-31 | 2007-04-05 | Gillespie Iii Richard D | Auto-Injection Syringe Having Vent Device |
US20070135767A1 (en) * | 2005-12-08 | 2007-06-14 | Gillespie Richard D Iii | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
US20090287184A1 (en) * | 2005-05-02 | 2009-11-19 | Martin Nicholas Lee | Autoflush Syringe Method |
US8529517B2 (en) | 2005-05-02 | 2013-09-10 | Shi Zi Technology, Ltd. | Autoflush syringe |
USD702834S1 (en) * | 2011-03-22 | 2014-04-15 | Medimop Medical Projects Ltd. | Cartridge for use in injection device |
US8936577B2 (en) | 2005-05-02 | 2015-01-20 | Shi Zi Technology, Ltd. | Methods and devices for autoflush syringes |
US9480797B1 (en) | 2015-10-28 | 2016-11-01 | Bayer Healthcare Llc | System and method for syringe plunger engagement with an injector |
US9694131B2 (en) | 2003-11-25 | 2017-07-04 | Bayer Healthcare Llc | Medical injector system |
US9744305B2 (en) | 2012-09-28 | 2017-08-29 | Bayer Healthcare Llc | Quick release plunger |
US9844622B2 (en) | 2000-07-10 | 2017-12-19 | Bayer Healthcare Llc | Syringes for medical injector systems |
US9855390B2 (en) | 2006-03-15 | 2018-01-02 | Bayer Healthcare Llc | Plunger covers and plungers for use in syringes |
USD847985S1 (en) | 2007-03-14 | 2019-05-07 | Bayer Healthcare Llc | Syringe plunger cover |
US10576207B2 (en) | 2015-10-09 | 2020-03-03 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
US10806852B2 (en) | 2014-03-19 | 2020-10-20 | Bayer Healthcare Llc | System for syringe engagement to an injector |
USD942005S1 (en) | 2007-03-14 | 2022-01-25 | Bayer Healthcare Llc | Orange syringe plunger cover |
US11311674B2 (en) | 2016-01-21 | 2022-04-26 | West Pharma. Services IL, Ltd. | Medicament delivery device comprising a visual indicator |
US11318254B2 (en) | 2015-10-09 | 2022-05-03 | West Pharma. Services IL, Ltd. | Injector needle cap remover |
US11338090B2 (en) | 2016-08-01 | 2022-05-24 | West Pharma. Services IL, Ltd. | Anti-rotation cartridge pin |
US11364337B2 (en) | 2016-01-21 | 2022-06-21 | West Pharma. Services IL, Ltd. | Force containment in an automatic injector |
US11389597B2 (en) | 2016-03-16 | 2022-07-19 | West Pharma. Services IL, Ltd. | Staged telescopic screw assembly having different visual indicators |
US11504481B2 (en) | 2007-10-02 | 2022-11-22 | West Pharma. Services IL, Ltd. | Anti-rotation feature for infusion pump cartridge |
US11672904B2 (en) | 2016-01-21 | 2023-06-13 | West Pharma. Services IL, Ltd. | Needle insertion and retraction mechanism |
USD1002840S1 (en) | 2007-03-14 | 2023-10-24 | Bayer Healthcare Llc | Syringe plunger |
US11819666B2 (en) | 2017-05-30 | 2023-11-21 | West Pharma. Services IL, Ltd. | Modular drive train for wearable injector |
US11883636B2 (en) | 2018-02-27 | 2024-01-30 | Bayer Healthcare Llc | Syringe plunger engagement mechanism |
US11969582B2 (en) | 2017-01-06 | 2024-04-30 | Bayer Healthcare Llc | Syringe plunger with dynamic seal |
US11998718B2 (en) | 2020-06-18 | 2024-06-04 | Bayer Healthcare Llc | System and method for syringe plunger engagement with an injector |
USD1031029S1 (en) | 2003-11-25 | 2024-06-11 | Bayer Healthcare Llc | Syringe plunger |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US841701A (en) * | 1906-03-16 | 1907-01-22 | Justin De Lisle | Hypodermic syringe. |
US1139368A (en) * | 1914-11-27 | 1915-05-11 | Jesse W Starr | Ampul. |
US2514575A (en) * | 1945-02-17 | 1950-07-11 | Howard T Hein | Introversion syringe |
US2549417A (en) * | 1949-08-10 | 1951-04-17 | Frederick M Turnbull | Syringe ampoule |
US3016896A (en) * | 1960-01-26 | 1962-01-16 | Wilton E Van Sickle | Disposable hypodermic syringe |
US3237815A (en) * | 1964-06-05 | 1966-03-01 | V P P Inc | Universal plunger |
US3253592A (en) * | 1962-06-08 | 1966-05-31 | Baxter Don Inc | Plastic syringe |
US3391518A (en) * | 1965-12-10 | 1968-07-09 | American Home Prod | Process and apparatus for breechfilling cartridge syringe units |
US3470671A (en) * | 1965-12-10 | 1969-10-07 | American Home Prod | Process and apparatus for the breech-filling and stoppering of cartridge syringe units |
-
0
- BE BE756550D patent/BE756550A/xx unknown
-
1969
- 1969-09-23 US US860223A patent/US3705582A/en not_active Expired - Lifetime
-
1970
- 1970-09-15 GB GB4400270A patent/GB1304224A/en not_active Expired
- 1970-09-21 SE SE12792/70A patent/SE363238B/xx unknown
- 1970-09-23 DE DE19702046953 patent/DE2046953A1/de active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US841701A (en) * | 1906-03-16 | 1907-01-22 | Justin De Lisle | Hypodermic syringe. |
US1139368A (en) * | 1914-11-27 | 1915-05-11 | Jesse W Starr | Ampul. |
US2514575A (en) * | 1945-02-17 | 1950-07-11 | Howard T Hein | Introversion syringe |
US2549417A (en) * | 1949-08-10 | 1951-04-17 | Frederick M Turnbull | Syringe ampoule |
US3016896A (en) * | 1960-01-26 | 1962-01-16 | Wilton E Van Sickle | Disposable hypodermic syringe |
US3253592A (en) * | 1962-06-08 | 1966-05-31 | Baxter Don Inc | Plastic syringe |
US3237815A (en) * | 1964-06-05 | 1966-03-01 | V P P Inc | Universal plunger |
US3391518A (en) * | 1965-12-10 | 1968-07-09 | American Home Prod | Process and apparatus for breechfilling cartridge syringe units |
US3470671A (en) * | 1965-12-10 | 1969-10-07 | American Home Prod | Process and apparatus for the breech-filling and stoppering of cartridge syringe units |
Cited By (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3824708A (en) * | 1972-12-26 | 1974-07-23 | Xerox Corp | Educational device |
US3824711A (en) * | 1972-12-26 | 1974-07-23 | Xerox Corp | Educational device |
US3910273A (en) * | 1973-03-08 | 1975-10-07 | Sven Arlers | Aspirating hypodermic syringe |
US3885710A (en) * | 1973-03-20 | 1975-05-27 | Cohen Milton | Mixing dispenser with a selectively retractable seal to permit intermixing of the ingredients |
US4188949A (en) * | 1977-07-05 | 1980-02-19 | Becton, Dickinson & Company | Sequential injection syringe |
US4950243A (en) * | 1987-11-27 | 1990-08-21 | Estruch Miracle C | Syringe for one sole use |
US5009646A (en) * | 1988-03-16 | 1991-04-23 | Daikyo Gomu Seiko Ltd. | Sliding stopper for a syringe |
US5207983A (en) * | 1992-01-29 | 1993-05-04 | Sterling Winthrop Inc. | Method of terminal steam sterilization |
US5256154A (en) * | 1992-01-31 | 1993-10-26 | Sterling Winthrop, Inc. | Pre-filled plastic syringes and containers and method of terminal sterilization thereof |
US5314415A (en) * | 1993-07-21 | 1994-05-24 | Sterling Winthrop Inc. | Aspirating plunger for power injector cartridges |
US5411488A (en) * | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having an improved plunger and plunger rod for reducing syringing force |
US5411489A (en) * | 1994-05-06 | 1995-05-02 | Sterling Winthrop Inc. | Pre-filled syringe and pre-filled cartridge having actuating cylinder/plunger rod combination for reducing syringing force |
US5413563A (en) * | 1994-05-06 | 1995-05-09 | Sterling Winthrop Inc. | Pre-filled syringe having a plunger, plunger insert and plunger rod |
USD383205S (en) * | 1994-05-06 | 1997-09-02 | Sterling Winthrop Inc. | Combined syringe and plunger |
US6322535B1 (en) | 1996-11-12 | 2001-11-27 | Medrad, Inc. | Prefillable syringes and injectors for use therewith |
US5947935A (en) * | 1996-11-12 | 1999-09-07 | Medrad, Inc. | Syringes, syringe plungers and injector systems |
US6017330A (en) * | 1996-11-12 | 2000-01-25 | Medrad, Inc. | Plunger systems |
US5873861A (en) * | 1996-11-12 | 1999-02-23 | Medrad, Inc. | Plunger systems |
US6984222B1 (en) | 1996-11-12 | 2006-01-10 | Medrad, Inc. | Plunger systems |
US5944694A (en) * | 1996-11-12 | 1999-08-31 | Medrad, Inc. | Prefillable syringes and injectors for use therewith |
US6395007B1 (en) * | 1999-03-16 | 2002-05-28 | American Osteomedix, Inc. | Apparatus and method for fixation of osteoporotic bone |
US20030036763A1 (en) * | 1999-03-16 | 2003-02-20 | Mohit Bhatnagar | Apparatus and method for fixation of osteoporotic bone |
US6887246B2 (en) * | 1999-03-16 | 2005-05-03 | American Osteomedix, Inc. | Apparatus and method for fixation of osteoporotic bone |
US20070078394A1 (en) * | 2000-05-31 | 2007-04-05 | Gillespie Iii Richard D | Auto-Injection Syringe Having Vent Device |
US9844622B2 (en) | 2000-07-10 | 2017-12-19 | Bayer Healthcare Llc | Syringes for medical injector systems |
FR2847883A1 (fr) * | 2002-11-29 | 2004-06-04 | Valois Sas | Systeme et procede de bouchage d'un reservoir et distributeur de produit fluide incorporant un tel systeme |
US10894124B2 (en) | 2003-11-25 | 2021-01-19 | Bayer Healthcare Llc | Medical injector system |
USD1031029S1 (en) | 2003-11-25 | 2024-06-11 | Bayer Healthcare Llc | Syringe plunger |
US11596735B2 (en) | 2003-11-25 | 2023-03-07 | Bayer Healthcare Llc | Medical injector system |
US10434249B2 (en) | 2003-11-25 | 2019-10-08 | Bayer Healthcare Llc | Medical injector system |
US9694131B2 (en) | 2003-11-25 | 2017-07-04 | Bayer Healthcare Llc | Medical injector system |
US7674246B2 (en) | 2004-12-09 | 2010-03-09 | West Pharmaceutical Services Of Delaware, Inc. | Automatic injection and retraction syringe |
US20060178629A1 (en) * | 2004-12-09 | 2006-08-10 | Pharma-Pen Holdings, Inc. | Coupling for an auto-injection device |
US7758548B2 (en) | 2004-12-09 | 2010-07-20 | West Pharmaceutical Services Of Delaware, Inc. | Coupling for an auto-injection device |
US20060178631A1 (en) * | 2004-12-09 | 2006-08-10 | Pharma-Pen Holdings, Inc. | Automatic injection and retraction syringe |
US8123724B2 (en) | 2004-12-09 | 2012-02-28 | West Pharmaceutical Services Of Delaware, Inc. | Auto-injection syringe having vent device |
US9539391B2 (en) | 2005-05-02 | 2017-01-10 | Shi Zi Technology, Ltd. | Methods and devices for autoflush syringes |
US11389589B2 (en) | 2005-05-02 | 2022-07-19 | Bee Sight Llc | Methods and devices for autoflush syringes |
US8936577B2 (en) | 2005-05-02 | 2015-01-20 | Shi Zi Technology, Ltd. | Methods and devices for autoflush syringes |
US8529517B2 (en) | 2005-05-02 | 2013-09-10 | Shi Zi Technology, Ltd. | Autoflush syringe |
US8075533B2 (en) | 2005-05-02 | 2011-12-13 | Preventiv, Inc. | Autoflush syringe |
US20090287184A1 (en) * | 2005-05-02 | 2009-11-19 | Martin Nicholas Lee | Autoflush Syringe Method |
US8075547B2 (en) | 2005-05-02 | 2011-12-13 | Preventiv, Inc. | Autoflush syringe method |
US20100114068A2 (en) * | 2005-05-02 | 2010-05-06 | Martin Lee | Autoflush Syringe Method |
US10322236B2 (en) | 2005-05-02 | 2019-06-18 | Bee Sight Limited | Methods and devices for autoflush syringes |
US20070135767A1 (en) * | 2005-12-08 | 2007-06-14 | Gillespie Richard D Iii | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
US7988675B2 (en) | 2005-12-08 | 2011-08-02 | West Pharmaceutical Services Of Delaware, Inc. | Automatic injection and retraction devices for use with pre-filled syringe cartridges |
US9855390B2 (en) | 2006-03-15 | 2018-01-02 | Bayer Healthcare Llc | Plunger covers and plungers for use in syringes |
US10668221B2 (en) | 2006-03-15 | 2020-06-02 | Bayer Healthcare Llc | Plunger covers and plungers for use in syringes |
USD1030051S1 (en) | 2007-03-14 | 2024-06-04 | Bayer Healthcare Llc | Syringe plunger |
USD1030052S1 (en) | 2007-03-14 | 2024-06-04 | Bayer Healthcare Llc | Syringe plunger |
USD847985S1 (en) | 2007-03-14 | 2019-05-07 | Bayer Healthcare Llc | Syringe plunger cover |
USD1002840S1 (en) | 2007-03-14 | 2023-10-24 | Bayer Healthcare Llc | Syringe plunger |
USD942005S1 (en) | 2007-03-14 | 2022-01-25 | Bayer Healthcare Llc | Orange syringe plunger cover |
US11590291B2 (en) | 2007-10-02 | 2023-02-28 | West Pharma. Services IL, Ltd. | External drug pump |
US11504481B2 (en) | 2007-10-02 | 2022-11-22 | West Pharma. Services IL, Ltd. | Anti-rotation feature for infusion pump cartridge |
USD702834S1 (en) * | 2011-03-22 | 2014-04-15 | Medimop Medical Projects Ltd. | Cartridge for use in injection device |
US10286152B2 (en) | 2012-09-28 | 2019-05-14 | Bayer Healthcare Llc | Quick release plunger |
US9744305B2 (en) | 2012-09-28 | 2017-08-29 | Bayer Healthcare Llc | Quick release plunger |
US10806852B2 (en) | 2014-03-19 | 2020-10-20 | Bayer Healthcare Llc | System for syringe engagement to an injector |
US11103637B2 (en) | 2014-03-19 | 2021-08-31 | Bayer Healthcare Llc | System for syringe engagement to an injector |
US11383029B2 (en) | 2014-03-19 | 2022-07-12 | Bayer Healthcare Llc | System for syringe engagement to an injector |
US11724034B2 (en) | 2015-10-09 | 2023-08-15 | West Pharma. Services, IL, Ltd. | Injector system |
US11110224B2 (en) | 2015-10-09 | 2021-09-07 | West Pharma. Services IL, Ltd. | Patch injector with slidable joint |
US12036394B2 (en) | 2015-10-09 | 2024-07-16 | West Pharma. Services IL, Ltd. | Injector needle cap and/or liner remover |
US10576207B2 (en) | 2015-10-09 | 2020-03-03 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
US11547802B2 (en) | 2015-10-09 | 2023-01-10 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
US11759573B2 (en) | 2015-10-09 | 2023-09-19 | West Pharma. Services, IL, Ltd. | Bent fluid path add on to a prefilled reservoir |
US11318254B2 (en) | 2015-10-09 | 2022-05-03 | West Pharma. Services IL, Ltd. | Injector needle cap remover |
US11547794B2 (en) | 2015-10-28 | 2023-01-10 | Bayer Healthcare Llc | System and method for syringe plunger engagement with an injector |
US9480797B1 (en) | 2015-10-28 | 2016-11-01 | Bayer Healthcare Llc | System and method for syringe plunger engagement with an injector |
US10512721B2 (en) | 2015-10-28 | 2019-12-24 | Bayer Healthcare Llc | System and method for syringe plunger engagement with an injector |
US11672904B2 (en) | 2016-01-21 | 2023-06-13 | West Pharma. Services IL, Ltd. | Needle insertion and retraction mechanism |
US11311674B2 (en) | 2016-01-21 | 2022-04-26 | West Pharma. Services IL, Ltd. | Medicament delivery device comprising a visual indicator |
US11364337B2 (en) | 2016-01-21 | 2022-06-21 | West Pharma. Services IL, Ltd. | Force containment in an automatic injector |
US12005237B2 (en) | 2016-01-21 | 2024-06-11 | West Pharma. Services IL, Ltd. | Medicament delivery device comprising a visual indicator |
US11389597B2 (en) | 2016-03-16 | 2022-07-19 | West Pharma. Services IL, Ltd. | Staged telescopic screw assembly having different visual indicators |
US11338090B2 (en) | 2016-08-01 | 2022-05-24 | West Pharma. Services IL, Ltd. | Anti-rotation cartridge pin |
US11969582B2 (en) | 2017-01-06 | 2024-04-30 | Bayer Healthcare Llc | Syringe plunger with dynamic seal |
US11819666B2 (en) | 2017-05-30 | 2023-11-21 | West Pharma. Services IL, Ltd. | Modular drive train for wearable injector |
US11883636B2 (en) | 2018-02-27 | 2024-01-30 | Bayer Healthcare Llc | Syringe plunger engagement mechanism |
US11998718B2 (en) | 2020-06-18 | 2024-06-04 | Bayer Healthcare Llc | System and method for syringe plunger engagement with an injector |
Also Published As
Publication number | Publication date |
---|---|
DE2046953A1 (de) | 1971-04-15 |
SE363238B (hu) | 1974-01-14 |
BE756550A (fr) | 1971-03-01 |
GB1304224A (hu) | 1973-01-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US3705582A (en) | Breech loaded syringe and method of breech loading same | |
US3834387A (en) | Breech loaded syringe with deformable piston | |
FI67025C (fi) | Injektionsspruta | |
US3699961A (en) | Syringe and method | |
US4809711A (en) | Prefilled ampoule-syringe | |
US5389076A (en) | Single use medical device with retraction mechanism | |
CA1071052A (en) | Injection syringe | |
US5616128A (en) | Self-injection device | |
US5997512A (en) | Retractable dental syringe | |
US3348546A (en) | Intermixing syringe | |
AU636115B2 (en) | An injection syringe needle | |
US5190523A (en) | Disposable syringe and injector | |
US4112945A (en) | Operator means for syringe cartridges | |
AU783051B2 (en) | Hypodermic syringe with selectively retractable needle | |
US3412906A (en) | Plasma infusor | |
US2854975A (en) | Hypodermic syringe | |
KR970702735A (ko) | 견인력이 작게 드는 주사기 및 카트리지(low drag syringe and cartridge) | |
KR19990076918A (ko) | 후퇴가능한 바늘과 주사기의 조합체 | |
SE467521B (sv) | Foerfylld spruta | |
US3986645A (en) | Liquid dispenser | |
JPH06190038A (ja) | 皮下注射器 | |
KR960705598A (ko) | 주사기 또는 유사한 장관외기구(syringe or like parenteral device) | |
US20160144117A1 (en) | Hypodermic syringe that automatically ejects medicament from a needle | |
EP2007452A1 (en) | Syringe with sequentially moving plunger flanges | |
US2655919A (en) | Hypodermic syringe and cartridge therefor |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: SHERWOOD MEDICAL COMPANY Free format text: MERGER;ASSIGNOR:SHERWOOD MEDICAL INDUSTRIES INC. (INTO);REEL/FRAME:004123/0634 Effective date: 19820412 |