US3694547A - Anti-dandruff hair preparation - Google Patents

Anti-dandruff hair preparation Download PDF

Info

Publication number
US3694547A
US3694547A US3694547DA US3694547A US 3694547 A US3694547 A US 3694547A US 3694547D A US3694547D A US 3694547DA US 3694547 A US3694547 A US 3694547A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
rennet
hair
example
dandruff
hair preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Ernst Ludwig Forsthoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CPPD Inc A CORP OF
Original Assignee
Lever Brothers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K8/00Cosmetics or similar toilet preparations
    • A61K8/18Cosmetics or similar toilet preparations characterised by the composition
    • A61K8/30Cosmetics or similar toilet preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/04Dandruff

Abstract

This invention relates to hair preparations having activity against dandruff, containing as an anti-dandruff agent the proteolytic enzyme material rennet. One form of the hair preparations is a lotion, for example an aqueous or alcoholic solution or emulsion of rennet having a pH of from 2 to 9. Rennet may also be incorporated in shampoos, creams, sprays and gels.

Description

United States Patent Forsthofi 1 Sept. 26, 1972 [54] ANTl-DANDRUFF HAIR PREPARATION [56] References Cited [72] Inventor: Ernst L ldwig Forsthoff, Schenefeld, OTHER PUBLICATIONS Kreis Pmneberg, Germany Cayle, Journal of the Society of Cosmetic Chemists, Vol. 14, No. 6, page 254, June 1963 [73] Assignee: Lever Brothers Company, New

York, Primary ExaminerRichard L. Huff N 5, Attorney-Louis Kline, J1. fit al.

[21] Appl. No.: 196,226 [57] ABSTRACT This invention relates to hair preparations having ac- [30] Foreign Application Priority Data tivity against dandruff, containing as an anti-dandruff agent the proteolytic enzyme material rennet. One 1970 Luxembourg "62030 form of the hair preparations is a lotion, for example an aqueous or alcoholic solution or emulsion of rennet [52] U.S. Cl. ..424/94, 424/DlG. 4 having a pH of from 2 to Rennet may also be incop Int. Cl. porated in shampoos, creams p y and g Field of Search ..424/DIG. ,4, 94, 7O

7 Claims, No Drawings ANTl-DANDRUFF HAIR PREPARATION This invention relates to hair preparations containing rennet and particularly to lotions containing rennet for the control of dandruff.

beneficial effect on the skin. It has also been suggested trypsin should be added to dental preparations in order to dissolve protein-containing food residues. Proteolytic enzymes, such as keratinase have also been suggested for use as depilatories.

Tryptic enzymes, such as pancreatin, have not proved very suitable for hair preparations, (which are generally acidic), since they are most effective at about pH 8.5. A similar objection is open to the use of lipases (mixtures of proteolytic enzymes) which have also been suggested.

We have now discovered that desirable effects can be imparted to hair preparations by the incorporation therein of rennet, and that these effects can be obtained from both acidicand weakly alkaline preparations.

Accordingly the present invention provides a hair preparation having activity against dandruff comprising, as an antidandruff agent from about 0.02 to about 1 percent by weight of rennet.

More particularly we have discovered that hair lotions containing rennet are effective in controlling dandruff.

Rennet isa substance normally used in cheese-making (and which is therefore commercially available) which contains the enzyme chymosin. It is usually prepared microbiologically; or alternatively it can be isolated from natural sources such as calves stomachs.

in" general the'amount of rennet required to give an acceptable antidandruff effect in the composition of the invention is from 0.0l to 1 percent, preferably 0.01 to 0.5 percent by weight.

The most suitable form of hair preparation according to the invention is a lotion, that is an aqueous, alcoholic or aqueous/alcoholic solution or emulsion containing rennet, although'other forms, for example shampoos, gels and creams are not excluded. Preferably the pH of the preparation will be from 2 to 9, most preferably from 4.5 to 7. A particularly preferred mode of obtaining a composition within the pH range is to formulate it to include a buffer so that it is buffered at from about pH 5-6. r

The invention will be further described in the following examples in which the rennet used was of the activity stated in brackets:

EXAMPLE 1 This is an example of an alcoholic hair lotion by weight Rennet l :220,000) 0.05

lsopropanol 50.00

Perfume 0.30

Water balance EXAMPLEZ This is an example of an aqueous hair lotion I: by weight Rennet l:220,000) 0.05 Sodium benzoate 0. l 5 Perfume 0.2 Water balance EXAMPLE 3 This is an example of an aqueous/alcoholic hair setting preparation by weight Luviskol VA64 2.0 Rennet l:l00,000) 0.1 lsopropanol 45.0 Perfume 0.4 Water balance Luviskol VA64 (Trade Mark) is a commercially available polyvinylpyrrolidone/vinyl acetate copolymer.

EXAMPLE 4 This is an example of a hair preparation in the form of a gel Carbopol 940 (Trade Mark) is a carboxyvinyl polymer which functions as a thickening agent.

EXAMPLE 5 This is an example of a hair cream preparation by weight Paraffin Oil 1 Lanolin Glycerine Cityl alcohol Lanette N Rennet (l:l00,00) p-l-lydroxybenzoic acid-ethyl ester Perfume Water balance Lanette N (Trade Mark) is a 9:1 mixture of cetyl stearyl alcohol/sodium cetyl stearyl sulphate.

EXAMPLE 6 This is an example of a hair preparation in the form of a conditioner by weight Katioran (Trade Mark) is a hydrophilic fatty acid condensation product.

EXAMPLE 7 This is an example of a hair preparation in the form of a shampoo by weight Sodium alkyl polyglycol ether sulphate l5.2 Ethylene glycol distearate l.0 Sodium chloride 2.0 Technical grade rennet powder 0.5 Perfume 0.5 Water balance The composition was adjusted to pH 5.5 with citric acid.

EXAMPLE 8 This is an example of a hair preparation in the form of a cream lotion k by weight Stearyl alcohol 3.5 Stearyl alcohol polyglycol ether 3.5 Spermaceti 5.0 lsopropyl myristate 3.0 Glycerine 5.0 Technical grade rennet powder 0.1 Perfume 0.4 Water balance This composition was emulsified and found to have a pH of 6.4.

EXAMPLE 9 The following experiment was performed to ascertain the effectiveness of a lotion of the formulation shown in Example 1 in combatting dandruff.

A group of 100 people with bad or moderate dandruff were asked to apply the lotion twice a day and to wash their hair at the beginning of the trial period but not during it. A second group of 100 were asked to apply a lotion of the following formula in the same way:

i: by weight Salicyclic acid 2 isopropanol 48 Water 50 A third group of were asked to apply a 50 percent aqueous solution of isopropanol as a blank. The results of these tests are given in Table i.

TABLE 1 Number of persons showing a marked reduction of dandruff after use of lotion No. of days Lotion with elapsed Lotion of Ex. I salicyclic acid Blank lotion 3 I8 29 i2 6 26 38 l8 10 3| 54 22 I4 52 63 28 After 14 days the treatment was discontinued and the number of persons whose hair condition relapsed was noted. The results of this part of the experiment are shown in Table 2.

tive than one containing salicylic acid and salicylic acid lotions have been suggested as antidandruff agents in the past.

What is claimed is:

l. A hair preparation having activity against dandruff comprising, as an anti-dandruff agent from about 0.0] to about 1 percent by weight of rennet.

2. A hair preparation according to claim 1 wherein the rennet is in aqueous or alcoholic emulsion or solution.

3. A hair preparation according to claim 1 in the form of a lotion.

4. A hair preparation according to claim 1 in the form of a shampoo.

5. A hair preparation according to claim 1 having a pH of from about 2 to about 9.

6. A hair preparation according to claim 5 having a pH of from about 4.5 to about 7.

7. A hair preparation according to claim 6 having a pH buffered at from about 5 to about 6.

Claims (6)

  1. 2. A hair preparation according to claim 1 wherein the rennet is in aqueous or alcoholic emulsion or solution.
  2. 3. A hair preparation according to claim 1 in the form of a lotion.
  3. 4. A hair preparation according to claim 1 in the form of a shampoo.
  4. 5. A hair preparation according to claim 1 having a pH of from about 2 to about 9.
  5. 6. A hair preparation according to claim 5 having a pH of from about 4.5 to about 7.
  6. 7. A hair preparation according to claim 6 having a pH buffered at from about 5 to about 6.
US3694547A 1970-11-10 1971-11-05 Anti-dandruff hair preparation Expired - Lifetime US3694547A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
LU62030 1970-11-10

Publications (1)

Publication Number Publication Date
US3694547A true US3694547A (en) 1972-09-26

Family

ID=19726533

Family Applications (1)

Application Number Title Priority Date Filing Date
US3694547A Expired - Lifetime US3694547A (en) 1970-11-10 1971-11-05 Anti-dandruff hair preparation

Country Status (6)

Country Link
US (1) US3694547A (en)
CA (1) CA958646A (en)
DE (1) DE2153386C3 (en)
ES (1) ES396848A1 (en)
FR (1) FR2113863B1 (en)
LU (1) LU62030A1 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949087A (en) * 1971-07-06 1976-04-06 Labaz Method of suppressing seborrhea
US5834409A (en) * 1995-03-31 1998-11-10 Colgate-Palmolive Company Scalp care products containing anti itching/anti irritant agents
US6375948B1 (en) * 1999-07-12 2002-04-23 Kao Corporation Treating method for suppressing hair growth
USRE37872E1 (en) * 1989-02-16 2002-10-08 Inhale Therapeutics Systems, Inc. Storage of materials
USRE38385E1 (en) * 1989-02-16 2004-01-13 Nektar Therapeutics Storage of materials
US20080207928A1 (en) * 2005-03-12 2008-08-28 Ranjit Bhogal Hair and/or Scalp Care Compositions Incorporating Flavonoid Compounds
US20080206180A1 (en) * 2005-03-12 2008-08-28 Ranjit Bhogal Hair and/or scalp Care Compositions Incorporating Amino-Oxo-Indole-Ylidene Compounds
US20080255082A1 (en) * 2005-03-12 2008-10-16 Ranjit Bhogal Hair and/or Scalp Care Compositions Incorporating Terpenoid Compounds
US7744925B2 (en) 1994-12-02 2010-06-29 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US20110243876A1 (en) * 2010-04-01 2011-10-06 Rajan Keshav Panandiker Organosilicones

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Cayle, Journal of the Society of Cosmetic Chemists, Vol. 14, No. 6, page 254, June 1963 *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949087A (en) * 1971-07-06 1976-04-06 Labaz Method of suppressing seborrhea
USRE39497E1 (en) * 1989-02-16 2007-02-27 Nektar Therapeutics Storage of materials
USRE38385E1 (en) * 1989-02-16 2004-01-13 Nektar Therapeutics Storage of materials
USRE37872E1 (en) * 1989-02-16 2002-10-08 Inhale Therapeutics Systems, Inc. Storage of materials
US7785631B2 (en) 1994-12-02 2010-08-31 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US7744925B2 (en) 1994-12-02 2010-06-29 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US7780991B2 (en) 1994-12-02 2010-08-24 Quadrant Drug Delivery Limited Solid dose delivery vehicle and methods of making same
US5834409A (en) * 1995-03-31 1998-11-10 Colgate-Palmolive Company Scalp care products containing anti itching/anti irritant agents
US7056499B2 (en) 1999-07-12 2006-06-06 Kao Corporation Treating method for suppressing hair growth
US7211278B2 (en) 1999-07-12 2007-05-01 Kao Corporation Treating method for suppressing hair growth
US6375948B1 (en) * 1999-07-12 2002-04-23 Kao Corporation Treating method for suppressing hair growth
US20080206180A1 (en) * 2005-03-12 2008-08-28 Ranjit Bhogal Hair and/or scalp Care Compositions Incorporating Amino-Oxo-Indole-Ylidene Compounds
US20080255082A1 (en) * 2005-03-12 2008-10-16 Ranjit Bhogal Hair and/or Scalp Care Compositions Incorporating Terpenoid Compounds
US20080207928A1 (en) * 2005-03-12 2008-08-28 Ranjit Bhogal Hair and/or Scalp Care Compositions Incorporating Flavonoid Compounds
US7807707B2 (en) * 2005-03-12 2010-10-05 Conopco Inc. Hair and/or scalp care compositions incorporating amino-oxo-indole-ylidene compounds
US20110243876A1 (en) * 2010-04-01 2011-10-06 Rajan Keshav Panandiker Organosilicones
US9212338B2 (en) 2010-04-01 2015-12-15 The Procter & Gamble Company Organosilicones
US9650593B2 (en) 2010-04-01 2017-05-16 The Procter & Gamble Company Organosilicones

Also Published As

Publication number Publication date Type
ES396848A1 (en) 1975-04-01 application
LU62030A1 (en) 1972-07-26 application
FR2113863A1 (en) 1972-06-30 application
DE2153386A1 (en) 1972-05-18 application
DE2153386C3 (en) 1978-04-13 grant
CA958646A (en) 1974-12-03 grant
FR2113863B1 (en) 1975-08-29 grant
DE2153386B2 (en) 1977-08-25 application
CA958646A1 (en) grant

Similar Documents

Publication Publication Date Title
US5843411A (en) Stabilization of ascorbic acid, ascorbic acid derivatives and/or extracts containing ascorbic acid for topical use
US4567038A (en) Sunscreen composition for hair protection
US5314873A (en) Milk-protein hydrolyzates and compositions for use as hair and skin treating agent
US3829563A (en) Emollient cleansing compositions
US4369180A (en) Cosmetic facial preparation containing aloe vera
US4126674A (en) Thickened aqueous shampoo compositions containing encapsulated conditioning agents
US5073545A (en) Agent containing an ellagic acid series compound for external application and use thereof
US5523078A (en) Method of preparing and composition for treatment of hair and scalp
US4822601A (en) Cosmetic base composition with therapeutic properties
EP0155737A2 (en) Low irritating shampoo compositions
US4186113A (en) Low irritating detergent compositions
US5053219A (en) Cosmetic products containing milk constituents
US5503825A (en) Lip balm composition
US4390033A (en) Stable hair relaxer
US3842847A (en) Shampoo compositions and method for treating the human hair and scalp employing certain astringent salts
US4495079A (en) Facial skin cleanser capable of softening and removing sebum plaque
US5017367A (en) Skin treatment preparation
US6117436A (en) Cosmetic care product with two components
EP0532219A2 (en) Cosmetic composition
US4474763A (en) Skin preparation
US4234566A (en) Antihistamine and methods for use thereof
US5437860A (en) Skin and scalp barrier for use with hair treatment products
US4129644A (en) Protecting skin and hair with cosmetic compositions containing superoxide dismutase
US5750107A (en) Hair growth promoter
US4370315A (en) Post-depilatory composition reducing progressively the growth of body hair

Legal Events

Date Code Title Description
AS Assignment

Owner name: CPPD, INC., C/O CT CORPORATION SYSTEM 208 LASALLE

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:LEVER BROTHERS COMPANY, A CORP. OF ME;REEL/FRAME:004888/0628

Effective date: 19880101

Owner name: CPPD, INC., A CORP. OF IL, ILLINOIS

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:LEVER BROTHERS COMPANY, A CORP. OF ME;REEL/FRAME:004888/0628