US3633566A - Blood collecting method and device - Google Patents

Blood collecting method and device Download PDF

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Publication number
US3633566A
US3633566A US824977A US82497769A US3633566A US 3633566 A US3633566 A US 3633566A US 824977 A US824977 A US 824977A US 82497769 A US82497769 A US 82497769A US 3633566 A US3633566 A US 3633566A
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Prior art keywords
needle
tubes
tube
stoppers
holding
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US824977A
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Robert H Grabhorn
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SYSTEMATIKS Inc
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Systematics
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Publication date
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Priority to US824977A priority Critical patent/US3633566A/en
Priority to CA080659A priority patent/CA926718A/en
Priority to SE05874/70A priority patent/SE354962B/xx
Priority to DE19702022116 priority patent/DE2022116A1/en
Priority to GB2174370A priority patent/GB1313331A/en
Priority to FR7017413A priority patent/FR2047706A5/fr
Priority to BE750378D priority patent/BE750378A/en
Priority to NL7007075A priority patent/NL7007075A/xx
Priority to US00205941A priority patent/US3765402A/en
Application granted granted Critical
Publication of US3633566A publication Critical patent/US3633566A/en
Anticipated expiration legal-status Critical
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150251Collection chamber divided into at least two compartments, e.g. for division of samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150267Modular design or construction, i.e. subunits are assembled separately before being joined together or the device comprises interchangeable or detachable modules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150496Details of construction of hub, i.e. element used to attach the double-ended needle to a piercing device or sampling device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150763Details with identification means
    • A61B5/150786Optical identification systems, e.g. bar codes, colour codes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150839Aesthetic features, e.g. distraction means to prevent fears of child patients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/155Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150259Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150992Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S604/00Surgery
    • Y10S604/903Medical container with material agitation means

Definitions

  • a blood specimen collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper. hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle. and flexible tube means for connecting the needle means to the vein-puncturing needle.
  • the means for holding the tubes is arranged so that the stoppers face the needle means. and drive means is arranged to provide relative reciprocation between the needle means and the tube holding means to cause the needle means to penetrate through such stoppers.
  • the device includes means for gently oscillating such tubes while blood is being drawn therein.
  • ROBERT HGRABHORN MYM ATTORNEYS BLOOD COLLECTING METHOD AND DEVICE My invention relates to the collection of blood specimens, and more particularly to the provision of a device for collecting blood specimens from a person's vein, which specimens are usable for testing the blood. My invention does not relate to the taking of blood for use in. transfusions.
  • My device is designed for use with conventional evacuated blood test tubes, each of which is sealed with a conventional rubber or rubberlike sealing stopper.
  • the use of such conventional evacuated test tubes for collecting blood specimens is well known. Specifically, it is common practice to take several blood specimens from a person by sticking the forward end of a double-ended hollow needle into one of the persons veins and then sequentially pushing the rear end of the needle into and through the sealing stoppers of the requisite number of tubes. While this practice is widely used, it suffers from several disadvantages. First of all, the forward end of the doubleended needle is left in the persons vein during the entire process while the requisite number of tubes are at least partially filled with blood.
  • stoppers of such tubes must be pushed onto and pulled from the rear end of the double-ended needle while the forward end of the needle is extending into the vein.
  • An inexperienced nurse or technician may accidentally shift the forward end of the needle seriously to damage the vein wall, In fact even an experienced nurse or technician may damage the vein with the forward end of the needle if the person from whom the blood specimens are being taken jerks or moves suddenly.
  • conventional devices do not facilitate proper agitation ofthe blood specimens.
  • My apparatus is constructed so that several of such tubes can be either simultaneously or sequentially filled without, in any way, manipulating or moving the needle which punctures and extends into the vein. Specifically, it is my concept to provide a veimpuncturing needle which is connected by means of a flexible tube to means for admitting the blood to the evacuated tubes.
  • my blood specimen collecting device broadly speaking, comprises means for holding conventional evacuated test tubes, each of which is sealed with a conventional stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, and flexible tube means for connecting the needle means to the vein-puncturing needle.
  • the tube holding means of my device is arranged so that the stoppers of the tubes face the needle means. I provide drive means for producing relative reciprocation between the needle means and the tube holding means to cause the needle means to penetrate through such stoppers.
  • the needle means for penetrating the stopper includes a single hollow needle which is connected by the flexible tube means to the vein-puncturing needle, and this single needle is sequentially penetrated through the stoppers of the desired number of tubes.
  • the needle means includes a plurality of hollow needles, each of which is connected to the vein-puncturing needle by the flexible tube means.
  • my drive means is arranged simultaneously to penetrate each of the hollow needles of the needle means through, respectively, the stoppers of the tubes.
  • One preferred embodiment of my invention is a device which is constructed within a small casing the upper surface of which provides a padded resting place for the arm of the person from whom blood is to be taken.
  • My device can be placed by a seat in a doctors office or in a laboratory and it can be stylishly decorated so as not to appear to be a clinical instrument.
  • the nurse or technician can pull the vein-puncturing needle from a small opening in the side of the device, remove the conventional protective covering from the needle, insert the forward end of the needle into the vein of the arm and then quickly operate the switch which operates the drive means of the device.
  • the person from whom the blood is drawn does not have to see and preferably cannot seen the tubes into which the blood is drawn. In fact, preferably, the person can only see the needle which extends into the vein and a small portion of the flexible tubing leading away from this needle.
  • the evacuated tubes into which the blood is drawn contain materials, such as preservatives, coagulants and anticoagulants, with which the blood must be thoroughly mixed promptly after or immediately as soon as it is withdrawn from the vein. It is well known that, if the blood is not properly mixed with this material, which is usually in powder form, the tests made on the blood may, at best, be inconclusive. Technicians and nurses who take blood specimens are instructed gently to oscillate each evacuated tube after its stopper is pulled off of the rear end of the needle which is extending into the vein. This is, of course, a manual operation which lengthens the process of taking the blood.
  • the function of gently oscillating the tube for a significant period of time properly to mix the blood with the material contained in the tube cannot be overly emphasized. If the blood is not agitated sufficiently to cause it to mix with the material in the tube, the tests on the blood may be totally inconclusive. If the blood is overly agitated, the blood cells may be damaged to the point where the tests on the blood will be inconclusive. Further, if the blood is not mixed properly with the material in the tube promptly after or, in some cases, immediately as soon as it is drawn into the tube, the tests on the blood may be inconclusive.
  • my blood collecting device includes means for continuously and gently oscillating the tubes while the blood is drawn therein and for a predetermined and desired period thereafter.
  • the drive means which causes the needle means to penetrate the stoppers of the tubes cannot be energized until the means for continuously and gently oscillating the tubes is energized.
  • FIG. 1 is an exploded, perspective view, partially sectioned, showing one embodiment of my invention
  • FIG. la is a schematic showing the type of controls which may be used with the embodiment of FIG. 1;
  • FIG. 2 is an exploded, perspective view showing a cartridge means for holding a plurality of conventional evacuated test tubes, which cartridge means is usable with the embodiment of FIG. 1 as well as other embodiments ofmy invention;
  • FIG. 3 is a perspective view, partially sectioned, of a generally triangularly shaped cartridge means for holding evacuated test tubes;
  • FIG. 4 is an exploded, perspective view showing a generally triangularly shaped cartridge for holding the test tubes and the needle means for penetrating through the stoppers of the test tubes;
  • FIG. 5 is a somewhat diagrammatical view showing a single hollow needle for penetrating through the stoppers of a plurality of tubes held in a generally triangularly shaped cartridge, indexing means for sequentially positioning the stopper of each tube adjacent the single needle and drive means for driving the needle through the stoppers;
  • FIG. 6 is another somewhat diagrammatical view showing a generally triangularly shaped cartridge holding three such evacuated tubes, a single needle for penetrating through the stoppers of the tubes, indexing means for sequentially moving the needle into position adjacent each of the stoppers, and means for driving the stoppers onto the needle;
  • FIG. 7 is another somewhat diagrammatical view showing a cartridge, such as in FIG. 2, indexing means for moving the cartridge in a step-by-step manner past a single needle and drive means for penetrating the needle sequentially through each of the stoppers;
  • FIG. 8 is another somewhat diagrammatical view showing a cartridge, such as in FIG. 2, a single needle, indexing means for moving the needle in a step-by-step manner sequentially to position the needle adjacent each of the stoppers and drive means for driving the stoppers onto the needle;
  • FIG. 9 is a fragmentary, perspective view showing a chuck or chuck means for releasably and rigidly holding a hollow needle which is used to penetrate through a tube stopper;
  • FIG. 10 shows a chuck means for holding a needle, means for holding a tube so that its stopper faces the needle and means mounting the chuck means for reciprocation toward and away from the stopper;
  • FIG. 11 is still another somewhat diagrammatical view showing a chuck means for holding a needle which penetrates through stoppers of tubes, a cartridge belt carrying a plurality of such tubes, indexing means for advancing the cartridge belt, means for driving the needle through the stoppers and means for separating each loop of the belt to provide discrete tubes; and
  • FIG. 12 is a further diagrammatical view showing cartridge means for holding a plurality of tubes, a single needle and drive means for picking a tube from the cartridge means and driving its stopper onto the needle.
  • my device 10 as comprising a housing 12 having a bottom wall 14, sidewalls 16, 18, end walls 20, 22 and a cover 24 which fits down over the sidewalls.
  • the cover 24 is provided with an upwardly facing, padded surface 26 upon which a person may comfortably rest an arm.
  • the cover may be cut away or formed as indicated at 27 and the end wall 22 may be inclined upwardly and inwardly to provide a cavity in which a conventional electric switch 28 is located. The purpose of this switch will be discussed in detail hereinafter.
  • the device 10 may be as decorative as desired.
  • the housing 12, including the cover 24, may be constructed from any suitable material, such as metal or plastic.
  • the total length of the device 10 need not be much greater than the length of a person s forearm.
  • the width of the device may be, for instance, 6 inches.
  • cover 24 While I have illustrated the cover 24 as being arranged to slip down over the end wall and sidewalls 16, 18, it will be appreciated that the cover may be hingedly mounted in a conventional manner to swing upwardly.
  • I provide an elongated platform 30 which my be gently oscillated by means of a conventional electric motor 32.
  • me motor 32 is mounted on the bottom I4 and its output shaft 34, which is bent is illustrated, extends upwardly therefrom.
  • the platform 30 may be connected to the bent shaft 34 by means such as illustrated bearing 36.
  • the inner race 38 of which is mounted on the upper end of the bent shaft and the outer race 40 of which is connected to the platform.
  • I may provide means such as the illustrated spring means 42 extending between portions of the housing 12 and the platform 30 yieldably to hold the platform 30 in position. Further, I may provide means, such as the illustrated walls 31, 31' for confining the movement of the platform.
  • the platform 30 is oscillated in all directions as indicated by the arrows 46, 48.
  • the motor 32 be a relatively low-speed motor so that this oscillation of the platform 30 will be gentle and smooth. The reason for gently oscillating the platform 30 is to mix thoroughly the blood drawn into the test tubes with the materials contained therein.
  • the platform 30 provides a longitudinally extending, square-walled trackway 50 and a pair of longitudinally and vertically extending sidewalls 52, 54, the sidewalls and the trackway providing a guideway for receiving a cartridge 56 (FIGS. 1 and 2) containing, in the illustrative embodiment, three evacuated blood test tubes 58, 60, 62, each of which is sealed with a conventional rubberlike stopper 58a, 60a, 62a.
  • the cartridge 56 may be provided with a guide strip 64 which is slidably received in the trackway 50 to guide the cartridge for movement along the platform 30.
  • I provide a pusher plate 68 which is arranged for reciprocation in the guideway provided by sidewalls 52, 54, the pusher plate being provided with a downwardly extending tang 70 which slidably engages the trackway 50.
  • An internally threaded tube 72 extends rearwardly from the pusher plate 68 as illustrated.
  • I provide a motor 74 which is mounted on the rear end of the platform 30 as illustrated, the motor 74 driving an externally threaded shaft 76 which threadedly engages the tube 72.
  • the pusher plate 68 moves in the direction of the arrow 78 and, when the motor 74 is energized to drive the shaft 76 in the opposite direction, the pusher plate 68 moves in the opposite direction.
  • the manifold 86 is formed with an internal passageway 94 which is in comm unication with the needles 88, 90, 92.
  • a flexible plastic tube 96 preferably made from a hemorepellant material, connects the passageway 94 and, therefore, the needles 88, 90, 92, to a vein-puncturing needle 98. I prefer to provide a gripper on the vein-puncturing needle 98 as illustrated.
  • each end of the manifold 86 is provided with a corner notch for receiving the end 82, 84 of the adjacent wall 52, 54. This is one scheme for holding the manifold 86 in a desired position relative to the platform 30.
  • the nurse or technician responsible for taking blood specimens will remove the manifold 86 including the needles 88, 90, 92 from a sanitary package and place the manifold in its illustrated position on the platform 30. Then, the nurse or technician will drop a cartridge 56 into the guideway provided by the trackway 50 and the sidewalls 52, 54 with the stoppers 58a, 60a, 62a facing the needles 88, 90, 92.
  • each of the needles 88, 90, 92 is coaxially aligned with the stopper 58a, 60a, 62:: through which the needle will penetrate.
  • the nurse or technician With the cartridge 56 and the manifold 86 in position, the nurse or technician will energize the motor 32 gently to oscillate the platform 30. Then, after the vein-puncturing needle 98 is inserted in to a vein, the motor 74 may be energized to drive the pusher plate 68 in the direction of the arrow 78 to cause the needles 88, 90, 92 to penetrate through, respectively, the stoppers 58a, 60a,
  • each of the support members 180, 182 is provided with a triangularly shaped cutout for receiving and engaging an end portion of the cartridge 146.
  • a rotary stepping drive motor 184 which is drivingly connected, by means indicated at 186, to the support member 180.
  • This motor 184 when energized, is arranged to drive the member 180 and the cartridge 146 through 120 step movements about the axis defined by the members 180, 182.
  • the means by which the members 180, 182 are mounted as well as the motor 184 and the transmission 186 may be conventional and need not be discussed, in detail, in this description.
  • the device 178 further comprises a block or a single channel manifold 188 which carries a single hollow needle 190 which is connected through a passageway in the block and a flexible tube 192 to a vein-puncturing needle 194.
  • the block 188 may be a plastic block formed with the passageway providing communication between the needle 190 and the tube 192 in the same manner that the manifold 86 is formed.
  • the needle 190 is preferably held so that it will extend toward the stoppers 154a sealing the tubes carried in the cartridge 146. Specifically, it is desirable that the needle 190 always be coaxially aligned with one of the tubes in the cartridge 146 carried by the support members 180, 182.
  • a drive motor 196 which may be drivingly connected to the block 188 by means such as the illustrated gear 198 and rack 200.
  • the block 188 is carried by the rack 200 and, when the motor 196 is driven in one direction, the needle 190 moves in the direction of the arrow 202 and, when the motor is driven the opposite direction, the needle 190 moves in the direction of the arrow 204.
  • the motor 184, 196, rack 200 and supports 180, 182 are mounted upon an oscillable platform 30, only a fragment of which is shown.
  • the nurse or technician taking the blood specimens will place the cartridge 146 in the support members 180, 182, place the block 188 in the proportioned cutout 206 in the rack 200 and, then, place the needle 194 into a vein.
  • the motor for oscillating the platform 30 is energized and then the motor 196 is energized to move the needle 190 in the direction of the arrow 202 to penetrate the needle through the coaxially aligned stopper 154a.
  • the motor 196 is again energized to move the needle 190 in the direction of the arrow 204 so that the motor 184 can be energized to rotate the cartridge 146 l to place another in coaxial alignment with the needle 190, and, thereafter, the needle 190 is again moved in the direction ofthe arrow 202 to deposit blood into the second coaxially aligned tube.
  • I may provide circuit means arranged sequentially to operate the indexing motor 184 and the drive motor 196 so that the nurse or technician taking the blood specimens need only throw one switch after the needle 194 is punctured into a vein.
  • the platform 30 is being gently oscillated to oscillate the tubes in the cartridge 146.
  • the rack 200 constitutes means for rigidly holding the hollow needle 190 and the cartridge 146 comprises means for supporting a plurality of conventional evacuated test tubes.
  • the motor 184 and transmission 186 and support member 180, 182 comprise indexing means for providing relative movement between the means which supports the needle 190 and the cartridge 146.
  • the motor 196 and the transmission 198 comprise drive means for providing relative reciprocation 8 between the support means for the needle 190 and the cartridge 146.
  • This device 210 comprises a support 212 upon which a cartridge 146' may be placed.
  • the support 212 provides a pair of spaced apart locating blocks 214, 216 which engage notches 218, formed in the edges of the cartridge 146' to prevent movement of the cartridge longitudinally, i.e., in the direction of the axes of the tubes in the cartridge, relative to the support 212.
  • the illustrative support 212 is reciprocated longitudinally by a drivescrew 220 which is driven by a motor not shown.
  • I have illustrated a manifold or block 188' and a single hollow needle 190 and means for sequentially positioning the needle adjacent the stopper 154a of each of the tubes in the cartridge 146.
  • I provide a rotary-stepping motor 222 for moving a support 224 which holds the block 188 in a step-bystep manner.
  • the motor 222 preferably moves the support 224 in 120 increments.
  • the cartridge 146 and the support 212 are proportioned and arranged so that one of the tubes in the cartridge 146 will he coaxially aligned with the needle 190' in each of its three positions obtained by energizing the motor 222.
  • the support 224 moves about an axis which is parallel to and equidistantly spaced from the axes of the tubes in the cartridge 146.
  • the nurse or technician taking blood specimens using the device 210 places the cartridge 146 on the support 212 as illustrated and then places the block 188' in the proportioned cutout 226 in the support 224. Then, after the needle 194 is inserted into the vein, the nurse or technician may operate a switch to cause the support 212 to be driven toward the needle to penetrate the needle through the stopper 154a of the first tube in the cartridge 146. After a predetermined time the support 212 is moved away from the needle 190' and then the motor 222 is energized to index the needle so that is is in coaxial alignment with the second tube in the cartridge 146.
  • the support 212, motor 222 and drivescrew 220 are preferably mounted on an oscillable platform 30, only a portion of which is shown.
  • the needle 190 is reciprocated axially toward and away from the stoppers of the tubes in the cartridge 146 and the cartridge is rotated about an axis in a stepby-step manner sequentially to position each stopper adjacent the needle.
  • the tubes and the cartridge are reciprocated toward and away from the needle 190 and the needle is driven about an axis in a step-by-step manner sequentially to be positioned adjacent each of the stoppers.
  • the device 230 utilizes the cartridge 56 which contains three tubes as discussed previously.
  • the cartridge 56 is placed upon a support 232 and held in position thereon by means such as the spring clip indicated at 234.
  • the support 232 and the cartridge 56 supported thereon is moved in a step-by-step manner as indicated by the two arrows 235 by a motor 236.
  • the motor 236 may be connected to the support 232 by means such as the illustrated drivescrew 238.
  • the motor 236 is, therefore, indexing means for moving the cartridge 56 in a step-by-step manner sequentially to position the stopper of each tube contained in the cartridge adjacent a single hollow needle 190.
  • the block 188 carrying the needle is placed in a cutout 239 on a support 240 which, in the illustrative embodiment, is drivingly connected to a motor 242 by a drivescrew 244.
  • the motor 242 is a bidirectional motor used to reciprocate the needle 190' toward and away from the carthrough tridge 56 sequentially to penetrate the needle 190' the stoppers of the tubes contained in the cartridge.
  • the above-described method is such that the only action required by the nurse or the technician after the needle 98 is inserted into the vein and before the needle is withdrawn from the vein is to throw a switch which energizes the motor 74.
  • the tube 96 is of sufficient length to permit the platform 30 to oscillate without, in any way, disturbing the position of the needle in a vein.
  • a plurality of conventional evacuated test tubes such as the three illustrated tubes 58, 60, 62 can be simultaneously at least partially filled with blood in a short period of time and without maneuvering the needle 98. Since the platform 30 can be oscillated before the needle 98 is inserted into the vein or, at least, before the motor 74 is energized, my device will begin to mix the blood drawn into the tubes 58, 60, 62 immediately with the material in the tubes. In fact, in order to assure such immediate mixing of the blood with the material in the tubes, I prefer to arrange my device 10 so that the motor 74 cannot be energized to drive the pusher plate 68 forward until the motor 32 is energized to oscillate the platform 30. As stated previously, this is an important object of my invention.
  • test tubes 58, 60, 62 While I have illustrated three test tubes 58, 60, 62, it will be appreciated that the cartridge 56 may contain more or less tubes as desired. Generally, in most blood tests, it is only desired that three such tubes be at least partially filled with blood.
  • FIG. la an illustrative control system for my device 10 will be discussed.
  • I show positive voltage terminals 102, 102' and negative voltage terminals 104, 104' providing power for my device 10. It will be appreciated that these terminals may represent the terminals of a battery power source or the output terminals of a conventional rectifier for alternating current.
  • the motor 32 is energized by current flow through a manually operated switch 106, the coil of a relay 108 and the master switch 28.
  • the relay 108 when energized, closes switch 110 through which the motor 74 is energized for rotation in a direction for driving the pusher plate 68 in the direction of the arrow 78.
  • Switches 112 and 116 are manually operated, double throw switches arranged, when thrown one way and switches 110 and 114 are closed, to drive motor 74 in one direction to advance plate 68 and, when thrown in the opposite way and switch 114 is closed, to drive motor 74 in the opposite direction to retract plate 68.
  • Switch 114 is normally closed and is opened by a tang 115 in the plate 68 when the plate has moved a predetermined distance in the direction of the arrow 78.
  • Switches 112 and 116 may be connected to a common actuator as illustrated.
  • the cartridge 56 is provided with three longitudinally extending, parallel openings 120, 122, 124 into which the tubes 58, 60, 62 are, respectively, inserted.
  • the mouths of these openings 120, 122, 124 are proportioned and designed snugly to engage, respectively, the stoppers 58a, 60a, 62a so that, when the cartridge is pushed in the direction of the arrow 78 by the pusher plate 68, the force exerted by the needles 88, 90, 92 upon the stoppers will not be directed through the walls of the tubes 58, 60, 62.
  • the further advantage of having the mouth of the openings 120, 122, 124 snugly engaging the stoppers 58a, 60a, 62a is that not all of the tubes which will be used with the cartridge will be of the same length.
  • test tubes 58, 60, 62 after they are at least partially filled with blood, are conventionally inserted into a plastic mailing package.
  • my cartridge 56 which is usable with the device 10 in the blood-drawing operation, can be used also as a mailing package.
  • FIG. 3 it will be seen that l have illustrated a generally triangularly shaped cartridge having an open end 132 through which three conventional evacuated tubes are inserted.
  • Inside the cartridge there are three triangularly related wall sections 134, 136, 138 providing cubicles for receiving the closed ends of the tubes which are inserted into the cartridge.
  • a centrally located, longitudinally extending stem 140 is arranged to extend from the intersection of the wall sections 134, 136, 138 to the open end 132 of the cartridge 130. The stem 140 separates the tubes which are inserted into the cartridge 130.
  • this stem 140 which is adjacent the open end 132 is proportioned and designed so that, when three tubes are inserted into the cartridge 130, the stoppers sealing the tubes are engaged snugly by portions of the perimeter of the open end 132 of the cartridge and by the adjacent end of the stem 140.
  • FIG. 4 it will be seen that l have illustrated another generally triangularly shaped cartridge 146 which provides a plurality of openings 148, 150, 152 which receive, respectively, conventional evacuated tubes, such as indicated at 154.
  • the openings 148, 150, 152 are also triangularly arranged so that, when tubes are, respectively, received therein, the axes of the tubes will extend through the corners of an equilateral triangle. The reason for this will become apparent as this description progresses.
  • I For use with the generally triangularly shaped cartridges 130, 146, I provide a generally triangularly shaped manifold 156 from which extends hollow needles 158, 160, 162, the manifold being provided with a passageway 164 in communication with the needles.
  • This passageway 164 is connected by means of a flexible tube 166 to a vein-puncturing needle 168.
  • the needles 158, 160, 162 are triangularly arranged so that each needle can be coaxially aligned with one of the openings 148, 150, 152 to be penetrated through the stopper of the tube disposed in the opening.
  • manifold 156 and either one of the cartridges 130, 146 may be used with my device 10.
  • I may provide a paper liner which can be fitted into the open end of the cartridge 146 so that, when the manifold 156 is pulled away from the cartridge, the blood drops on the needles 158, 160, 162 will drop into and be absorbed by the liner 170.
  • this liner 170, the manifold 156, tube 166 and needle 168 may be conventionally disposed of after the blood is deposited into the tubes carried in the cartridge 146.
  • FIGS. 2, 3 and 4 may be used with my device 10 simultaneously to deposit blood into the tubes disposed in the cartridges. Further, these same cartridges may be used with other embodiments of my invention which sequentially deposit blood into the tubes contained in the cartridge as will be hereinafter described.
  • the triangularly shaped cartridges 130, 146 may be preferable in some cases because they will stand alone on their bases, i.e., on their closed ends, to provide a self-standing unit with which the laboratory technicians can work. Further, for the same amount of material, a triangularly shaped cartridge may be somewhat stronger than a rectangularly shaped cartridge. Further, as will be discussed in conjunction with FIGS. 5-8, as a matter of mechanics, it may be advisable to index or position the triangularly shaped cartridges 130, 146 about a longitudinal axis.
  • the support 232, 240, 242 and the motor 236 are preferably mounted on an oscillable platform 30, only a portion ofwhich is shown.
  • FIG. 8 it will be seen that I have illustrated still another device 250 comprising a guideway 252 for slidably receiving a cartridge 56 and means 254 for drivingly connecting the cartridge to an illustrative drivescrew arrangement 256.
  • the drivescrew arrangement is provided for reciprocating the cartridge 56 in the guideway 252 as indicated by the arrows 258, 260 sequentially to push the stoppers of the tubes contained in the cartridge onto a single needle 190'.
  • the block 188' carrying the single needle 190' is disposed in a socket indicated at 262 provided in a support member 264 which is reciprocated in a step-by-step manner by a solenoid 266.
  • the solenoid 266 is connected to the support member 264 by means of a connecting device 268.
  • the device 268 comprises a pivotally mounted hook 270 which is arranged to engage notches 272, 274 provided on the support member 264.
  • a spring 276 is arranged yieldably to engage the hook with the notches.
  • the solenoid 266 comprises a plunger 278 which extends through an opening in the device 268, the distal end of the plunger 278 being provided with an enlarged end 280 which serves loosely to connect the end of the plunger to the device 268.
  • a spring 282 is arranged conventionally to urge the plunger 278 to its outermost position in the solenoid 266. I have illustrated a trip release 284 for manually disengaging the hook 270 from the notches 272, 274 and a spring 286 for biasing the support member 264 to its illustrated positron.
  • the connecting device 268 is mounted for slidable movement relative to the support member 264 within the limits established by the elongated slots 288. Assuming that the illustrated position of the support member 264 is its initial starting position and that the needle 190 has been penetrated through the opening 120' of the cartridge 56 and the stopper of the tube aligned with that opening and that it is desired to move the needle 190' into alignment with the opening 122, this movement is accomplished by energizing the solenoid 266 while the hook 270 is engaged with the notch 272 to move the needle 190' one step as indicated by the arrow 290. Then the cartridge 56 is driven in the direction of the arrow 258 to push the stopper of the tube aligned with the opening 122' upon the needle 190.
  • the solenoid 266 While the needle 190 is extending through the stopper behind the opening 122, the solenoid 266 is deenergized and the spring 282 moves the connecting device 268 to the left as viewed in FIG. 8 and relative to the support member 264 to engage the hook 270 with the notch 274. Then, after the cartridge 56 is pulled in the direction of the arrow 260, the solenoid 266 may again be energized to move the needle 190 one step as indicated by the arrow 292 to position the needle 190' in alignment with the opening 124. When the needle 190' is aligned with the opening 124, the cartridge 56 can be pushed in the direction of the arrow 258 to penetrate the needle through the stopper of the tube in alignment with the opening 124.
  • the blood-collecting operation is completed and while the needle 190' is still penetrating through the stopper of the tube aligned with the opening 124', the cartridge 56 with the needle and block 188 connected thereto can be lifted out of the guideway 252. Then, the supporting member 264 can be returned to its initial starting position by pushing down on the trip 284 which disengages the hook 270 from the notch 274.
  • I may use a solenoid for driving the single needle 190 through the stopper of each of the tubes in the cartridges 146, 56.
  • tube 192 and block 188 In order to prevent the blood which is contained in the needle 194, tube 192 and block 188 from running out the open end of the needle 194 after it is removed from a vein, I prefer to leave the needle 190 penetrating into the last three test tubes into which the needle is inserted. After the person from Whom the blood specimens have been taken leaves the area, the nurse or technician taking the blood can remove the needle from the last ofthe three tubes which is filled and then deposit the needle, block 188, flexible tube 192 and needle 194 into a trash container.
  • a chuck means 300 for releasably, but rigidly holding a hollow needle 302 so that stoppers of evacuated tubes can be pushed upon the needle, the needle being connected by means of a flexible tube 304 to a vein puncturing needle (not shown).
  • the illustrative chuck means 300 includes a member 306 providing a surface 306a having a trough 308 formed therein for receiving the needle 302, a second member 310 providing a second surface 310a for engaging the first-mentioned surface 306a, means 312 for hingedly connecting the members 306, 310 so that the surfaces 306a and 310a can be separated, and fastener means 314 for releasably holding the surfaces in engagement.
  • the illustrative fastener means 314 includes a wing screw 316 which is conventionally rotatable to bridge across a notch 318 provided in the member 310.
  • a resilient pad such as indicated at 320
  • a small plastic block such as indicated at 322, which is molded so as to be rigidly connected to the needle 302 and which is received in a recess 324 formed in the surface 306a. It will be appreciated that the engagement of the block 322 with the recess 324 will, when the surfaces 306a and 310a are brought into engagement, position when needle 302 against longitudinal movement.
  • a nurse or technician using the chuck means 300 may simply raise the upper member 310 and insert a needle 302 into the trough 308 as indicated by the arrows 326 and then, close the chuck means by lowering the upper member 310 and operating the fastener means 314.
  • the chuck means 300 it will be possible to eliminate the block 188, 188 shown in FIGS. 58, the block being a plastic piece of material having a passageway formed therein with a flexible tube connected to one end of the passageway and a needle extending into and connected to the other end of the passageway.
  • the formation of such a block will be significantly more expensive than the connection of the needle 302 to one end of the flexible tube 304.
  • I may provide chuck means 300 which will resiliently and frictionally engage the needle and hold the needle rigidly without using such a block.
  • the flexible tube 304 may be simply heat sealed to the needle 302.
  • My illustrative chuck means 300 may be used in any one of the systems illustrated in FIGS. 5-8. That is, the chuck means 300 may be placed on the rack 200 (FIG. 5), on the support member 224 (FIG. 6), on the support member 240 (FIG. 7), or on the support member 264 (FIG. 8).
  • the illustrative chuck means 300 mounted on a support block 330 for reciprocation in the direction of the arrow 332 which is parallel to the longitudinal axis of the needle 302 held in the chuck.
  • the illustrative chuck means 300 includes an illustrative snap fastener 334 in lieu of the rotatable-type fastener means 314 discussed above.
  • the support member 330 is formed with an upwardly opening, longitudinally extending cavity 336 for receiving a conventional evacuated tube 338, the end of the cavity 336 facing the chuck means 300 being enlarged as indicated at 340 to receive the stopper 338a sealing such a tube.
  • the tube 338 may be dropped into the cavity 336 and then the chuck means 300' may be pushed manually toward the tube to penetrate the needle 302 carried by the chuck means through the stopper 3380. After blood is drawn into the evacuated tube 338, the chuck means can be pulled away from the cavity 336 and the tube can be removed from the cavity and a second tube can be placed therein.
  • the device of FIG. 10, therefore, is a manual means for sequentially penetrating the needle 302, which is connected by a flexible tube 304 to a vein-puncturing needle, through the stoppers of several evacuated tubes.
  • a chuck means 300' for releasably and rigidly holding a hollow needle 302 and means 344 for reciprocating the chuck means toward and away from the stoppers of a plurality of tubes.
  • the illustrative means 344 includes a bidirectional drive motor 346 and drivescrew arrangement 348 for reciprocating the chuck means 300 as indicated by the arrow 350.
  • the tubes 352 are carried by a cartridge belt 354, i.e., a belt formed with a plurality of spaced apart loops 356, each of which receives a tube 352.
  • Each loop 356 of the belt 354 is preferably provided with coded indicia for identifying the tube received therein.
  • means such as the illustrated knife 358 which is pivotally mounted as indicated at 360, will be provided for separating the belt loops 356.
  • the knife 358 is pivotally mounted on the same member as the chuck means 300 so that when the chuck means is moved away from the tubes, the knife will drop down to separate the loop 356 from the belt 354. In some cases, it may be advisable to remove or to deactivate the knife 358 so that reciprocation of chuck means 300 will not separate belt loops.
  • a frame 362 defining a guideway through which the belt 354 and tubes 352 move.
  • a notch 364 through which the needle 302 reciprocates.
  • Means must be provided for driving the belt 354 in a step-by-step manner past the notch 364.
  • this function is provided by a rotary stepping motor 366 which drives a drive wheel 368 which engages the belt 354.
  • the drive wheel 368 may be soft so as resiliently to engage the belt 354 as illustrated.
  • each step of the motor 366 moves the belt 354 one loop space sequentially to advance each tube 352 carried by the belt past the notch 364.
  • the system of FIG. 11 may be ideally used for collecting large groups of blood specimens from large groups of people, such as Army inductees.
  • the coded indicia or serial numbers carried on each loop 356 will facilitate the identification of each blood specimen. That is, each person from whom blood is to be taken can be assigned a serial number corresponding to the number of the loop 356 receiving the tube 352 into which the persons blood is deposited.
  • one or more blood specimens can be efficiently taken from each person of a group of people. The nurse or technician taking the specimens will not have to manipulate manually the tubes.
  • the rotary stepping motor 366 and drive wheel 368 constitute indexing means for advancing the tubes 352 or the belt 354 holding the tubes sequentially past the chuck means 300 which holds the needles to be penetrated through the stoppers of the tubes.
  • FIG. 12 it will be seen that I have shown a block 188 carrying a needle 190, the block being mounted on a platform 30'.
  • the hollow needle 190 is connected by means of a flexible tube 192 to a vein-puncturing needle.
  • the block 188 is illustrative and chuck means 300 may be used in lieu thereof.
  • the system of FIG. 12 includes a chamber 382 in which tubes 384 are held for movement toward and away from the needle 190.
  • the chamber 382 is reciprocated toward and away from the needle 190 by means of a bidirectional motor 384 and drivescrew 386 arrangement.
  • the system of FIG. 12 also includes cartridge means or a hopper 388 for sequentially feeding such tubes 384 into the chamber 382 and means 390 for ejecting filled tubes from the chamber so that empty tubes can be deposited therein.
  • the ejecting means 390 comprises a member 392 mounted for pivotal movement as indicated at 394 toward and away from the chamber 382 as indicated by the arrow 395.
  • the member 392 provides a portion 396 for engaging a tube 384 and pushing it out of the chamber 382.
  • the ejecting means 390 also includes a second member 398 which is pivotally mounted on a platform 400 so as to engage a portion 402 of the member 392 when the chamber 382 is moved away from the needle I toward the cartridge means 388.
  • the member 398 is pivotally movable as indicated by the arrow 404 and a leaf spring 406 is provided for yieldably urging the member 398 in a direction opposite to the arrow 404.
  • FIG. 12 may be mounted on an oscillable platform 30', only a portion of which is shown.
  • a blood collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, flexible tube means for connecting said needle means to said vein-puncturing needle, said holding means being arranged to hold such tubes so that such stoppers face said needle means, drive means for providing relative reciprocation between said needle means and said holding means to cause said needle means to penetrate through such stoppers, and means for gently oscil lating said holding means and such tubes held thereby.
  • a blood collecting device comprising a manifold providing a passageway, a plurality of hollow needles carried by said manifold and communicating with said passageway, each of said hollow needles having a sharpened end portion extending away from said manifold, a vein-puncturing hollow needle, flexible tube means for connecting said vein-puncturing needle to said passageway, frame means for holding a plurality of conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, said frame means being arranged to hold each such tube in a position so that its stopper is facing the sharpened end portion of one of said first-mentioned needles, drive means for providing relative reciprocation between said manifold and said frame means to cause the sharpened end portions of said first-mentioned needles simultaneously and respectively to penetrate through said stoppers and into said tubes, and means for gently oscillating said frame means and such tubes held thereby.
  • a blood collecting device comprising a manifold providing a passageway, a plurality of hollow needles carried by said manifold and communicating with said passageway, each of said hollow needles having a sharpened end portion extending away from said manifold, a vein-puncturing hollow needle, flexible tube means for connecting said vein-puncturing needle to said passageway, frame means for holding a plurality of conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, said frame means being arranged to hold each such tube in a position so that its stopper is facing the sharpened end portion of one of said first-mentioned needles, drive means for providing relative reciprocation between said manifold and said frame means to cause the sharpened end portions of said first-men tioned needles simultaneously and respectively to penetrate through said stoppers and into said tubes, a platform upon which said frame means, manifold, and drive means are mounted, and means for gently oscillating said platform.
  • said oscillating means includes a motor, a bent shaft driven by said motor, and a bearing for coupling said platform to said shaft, said bearing having an outer race upon which said platform is mounted and an inner race mounted on said shaft.
  • a blood collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, flexible tube means for connecting said needle means to said vein-puncturing needle, said holding means being arranged to hold such tubes so that such stoppers face said needle means, power means for providing relative reciprocation between said needle means and said holding means to cause said needle means to penetrate through such stoppers, and means for gently oscillating said holding means and such tubes held thereby.
  • said needle means includes a second hollow needle and means for rigidly holding said second needle, and including indexing means for providing relative movement between said holding means and said second needle, said indexing means being arranged so that the stoppers of such tubes are sequentially disposed adjacent said second needle to be penetrated thereby.
  • a blood specimen collecting device comprising a veinpuncturing hollow needle, means for supporting a plurality of test tubes, each such tube being closed by sealing means disposed in the end thereof, hollow needle means, means for penetrating said hollow needle means through such sealing means and into such tubes, said penetrating means including power means for providing relative reciprocation between said hollow needle means and said supporting means, and means for gently oscillating said supporting means and the tubes supported thereby.
  • said hollow needle means includes a second hollow needle
  • said penetrating means includes indexing means for providing relative movement between said supporting means and said second hollow needle, said indexing means being arranged so that the sealing means of such tubes are sequentially disposed adjacent said second needle to be penetrated thereby.

Abstract

A blood specimen collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a veinpuncturing hollow needle, and flexible tube means for connecting the needle means to the vein-puncturing needle. The means for holding the tubes is arranged so that the stoppers face the needle means, and drive means is arranged to provide relative reciprocation between the needle means and the tube holding means to cause the needle means to penetrate through such stoppers. In many cases, such tubes contain materials, such as preservatives, coagulants and anticoagulants, with which the blood must be thoroughly mixed promptly after or immediately as soon as it is withdrawn from the vein. Thus, the device includes means for gently oscillating such tubes while blood is being drawn therein.

Description

United States Patent 72] Inventor Robert H. Grabhorn Greenwood, Ind.
[21] Appl. No. 824,977
[22] Filed May 15, 1969 [45] Patented Jan. 11, 1972 [73] Assignee Systematiks, Inc.
Indianapolis, Ind.
[54] BLOOD COLLECTING METHOD AND DEVICE 12 Claims, 13 Drawing Figs.
3,405,706 10/1968 Cingualbre 128/2 Primary Examiner-Warner H. Camp Attorney-Hood. Gust, lrish. Lundy & Coffey ABSTRACT: A blood specimen collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper. hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle. and flexible tube means for connecting the needle means to the vein-puncturing needle. The means for holding the tubes is arranged so that the stoppers face the needle means. and drive means is arranged to provide relative reciprocation between the needle means and the tube holding means to cause the needle means to penetrate through such stoppers. in many cases, such tubes contain materials, such as preservatives, coagulants and anticoagulants, with which the blood must be thoroughly mixed promptly after or immediately as soon as it is withdrawn from the vein. Thus, the device includes means for gently oscillating such tubes while blood is being drawn therein.
PATENTEB 33H! 1 I972 SHEEI 1 UF 4 E V m ROBERT FLG RAB HORN PATENTED m1 1 m2 3L633566 SHEET 2 OF 4 V INVENTOR. ROBERT H.GRABHORN zsawwww ATTORNEYS PATENTED JAN 1 i972 SHEET 3 OF 4 INVENTOR.
ROBERT H GRABHORN wawz w/flw ATTO R NEYS PATENTEUJANI 1 an 3633566 saw a or 4 INVENTOR. ROBERT HGRABHORN MYM ATTORNEYS BLOOD COLLECTING METHOD AND DEVICE My invention relates to the collection of blood specimens, and more particularly to the provision of a device for collecting blood specimens from a person's vein, which specimens are usable for testing the blood. My invention does not relate to the taking of blood for use in. transfusions.
My device is designed for use with conventional evacuated blood test tubes, each of which is sealed with a conventional rubber or rubberlike sealing stopper. The use of such conventional evacuated test tubes for collecting blood specimens is well known. Specifically, it is common practice to take several blood specimens from a person by sticking the forward end of a double-ended hollow needle into one of the persons veins and then sequentially pushing the rear end of the needle into and through the sealing stoppers of the requisite number of tubes. While this practice is widely used, it suffers from several disadvantages. First of all, the forward end of the doubleended needle is left in the persons vein during the entire process while the requisite number of tubes are at least partially filled with blood. This means that the stoppers of such tubes must be pushed onto and pulled from the rear end of the double-ended needle while the forward end of the needle is extending into the vein. An inexperienced nurse or technician may accidentally shift the forward end of the needle seriously to damage the vein wall, In fact even an experienced nurse or technician may damage the vein with the forward end of the needle if the person from whom the blood specimens are being taken jerks or moves suddenly. Further, as will be discussed hereinafter, conventional devices do not facilitate proper agitation ofthe blood specimens.
My apparatus is constructed so that several of such tubes can be either simultaneously or sequentially filled without, in any way, manipulating or moving the needle which punctures and extends into the vein. Specifically, it is my concept to provide a veimpuncturing needle which is connected by means of a flexible tube to means for admitting the blood to the evacuated tubes.
Thus, my blood specimen collecting device, broadly speaking, comprises means for holding conventional evacuated test tubes, each of which is sealed with a conventional stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, and flexible tube means for connecting the needle means to the vein-puncturing needle. The tube holding means of my device is arranged so that the stoppers of the tubes face the needle means. I provide drive means for producing relative reciprocation between the needle means and the tube holding means to cause the needle means to penetrate through such stoppers.
I have constructed my device in such a manner that the several tubes into which the blood is to be deposited and the needle means for puncturing through the stoppers of the tubes may be out of the sight of the person from whom the blood is to be taken. I prefer to use an electrically operated drive means for causing the needle means to penetrate through the stoppers so that a technician may merely insert the vein-puncturing needle into the vein and then operate a switch to cause the needle means to penetrate through the stoppers.
In one embodiment of my invention, the needle means for penetrating the stopper includes a single hollow needle which is connected by the flexible tube means to the vein-puncturing needle, and this single needle is sequentially penetrated through the stoppers of the desired number of tubes. In another embodiment of my invention, the needle means includes a plurality of hollow needles, each of which is connected to the vein-puncturing needle by the flexible tube means. In this embodiment, my drive means is arranged simultaneously to penetrate each of the hollow needles of the needle means through, respectively, the stoppers of the tubes.
One preferred embodiment of my invention is a device which is constructed within a small casing the upper surface of which provides a padded resting place for the arm of the person from whom blood is to be taken. My device can be placed by a seat in a doctors office or in a laboratory and it can be stylishly decorated so as not to appear to be a clinical instrument. When a person sits in the seat and places an arm upon the padded surface of my device, the nurse or technician can pull the vein-puncturing needle from a small opening in the side of the device, remove the conventional protective covering from the needle, insert the forward end of the needle into the vein of the arm and then quickly operate the switch which operates the drive means of the device. The person from whom the blood is drawn does not have to see and preferably cannot seen the tubes into which the blood is drawn. In fact, preferably, the person can only see the needle which extends into the vein and a small portion of the flexible tubing leading away from this needle.
In many cases, the evacuated tubes into which the blood is drawn contain materials, such as preservatives, coagulants and anticoagulants, with which the blood must be thoroughly mixed promptly after or immediately as soon as it is withdrawn from the vein. It is well known that, if the blood is not properly mixed with this material, which is usually in powder form, the tests made on the blood may, at best, be inconclusive. Technicians and nurses who take blood specimens are instructed gently to oscillate each evacuated tube after its stopper is pulled off of the rear end of the needle which is extending into the vein. This is, of course, a manual operation which lengthens the process of taking the blood.
The function of gently oscillating the tube for a significant period of time properly to mix the blood with the material contained in the tube cannot be overly emphasized. If the blood is not agitated sufficiently to cause it to mix with the material in the tube, the tests on the blood may be totally inconclusive. If the blood is overly agitated, the blood cells may be damaged to the point where the tests on the blood will be inconclusive. Further, if the blood is not mixed properly with the material in the tube promptly after or, in some cases, immediately as soon as it is drawn into the tube, the tests on the blood may be inconclusive.
In an attempt to obtain proper mixing of the blood with the material disposed in the tube into which the blood is drawn, nurses and technicians are often instructed gently to oscillate the tube after the blood is drawn therein to cause the bubble" in the tube to move from end to end of the tube a specific number of times without breaking or separating. In other words, when blood is drawn into an evacuated tube, there is left a bubble which is analogous to the bubble ofa conventional bubble level. If this bubble in the blood test tube is overly agitated, it will break up into several small segments.
In order to assure that the blood will be immediately and properly mixed with the materials in the tubes into which the blood is drawn, my blood collecting device includes means for continuously and gently oscillating the tubes while the blood is drawn therein and for a predetermined and desired period thereafter. In one preferred embodiment of my device, the drive means which causes the needle means to penetrate the stoppers of the tubes cannot be energized until the means for continuously and gently oscillating the tubes is energized.
Other objects and features of my invention will become apparent as this description progresses.
To the accomplishment of the above and related objects, my invention may be embodied in the forms illustrated in the accompanying drawings and the method described herein, attention being called to the fact, however, that the drawings and description are merely illustrative and that changes may be made in the specific constructions illustrated and described and in the methods described, so long as the scope of the appended claims is not violated.
In the drawings:
FIG. 1 is an exploded, perspective view, partially sectioned, showing one embodiment of my invention;
FIG. la is a schematic showing the type of controls which may be used with the embodiment of FIG. 1;
FIG. 2 is an exploded, perspective view showing a cartridge means for holding a plurality of conventional evacuated test tubes, which cartridge means is usable with the embodiment of FIG. 1 as well as other embodiments ofmy invention;
FIG. 3 is a perspective view, partially sectioned, of a generally triangularly shaped cartridge means for holding evacuated test tubes;
FIG. 4 is an exploded, perspective view showing a generally triangularly shaped cartridge for holding the test tubes and the needle means for penetrating through the stoppers of the test tubes;
FIG. 5 is a somewhat diagrammatical view showing a single hollow needle for penetrating through the stoppers of a plurality of tubes held in a generally triangularly shaped cartridge, indexing means for sequentially positioning the stopper of each tube adjacent the single needle and drive means for driving the needle through the stoppers;
FIG. 6 is another somewhat diagrammatical view showing a generally triangularly shaped cartridge holding three such evacuated tubes, a single needle for penetrating through the stoppers of the tubes, indexing means for sequentially moving the needle into position adjacent each of the stoppers, and means for driving the stoppers onto the needle;
FIG. 7 is another somewhat diagrammatical view showing a cartridge, such as in FIG. 2, indexing means for moving the cartridge in a step-by-step manner past a single needle and drive means for penetrating the needle sequentially through each of the stoppers;
FIG. 8 is another somewhat diagrammatical view showing a cartridge, such as in FIG. 2, a single needle, indexing means for moving the needle in a step-by-step manner sequentially to position the needle adjacent each of the stoppers and drive means for driving the stoppers onto the needle;
FIG. 9 is a fragmentary, perspective view showing a chuck or chuck means for releasably and rigidly holding a hollow needle which is used to penetrate through a tube stopper;
FIG. 10 shows a chuck means for holding a needle, means for holding a tube so that its stopper faces the needle and means mounting the chuck means for reciprocation toward and away from the stopper;
FIG. 11 is still another somewhat diagrammatical view showing a chuck means for holding a needle which penetrates through stoppers of tubes, a cartridge belt carrying a plurality of such tubes, indexing means for advancing the cartridge belt, means for driving the needle through the stoppers and means for separating each loop of the belt to provide discrete tubes; and
FIG. 12 is a further diagrammatical view showing cartridge means for holding a plurality of tubes, a single needle and drive means for picking a tube from the cartridge means and driving its stopper onto the needle.
Referring now to the drawings, and particularly to FIGS. 1 and 2, it will be seen that I have illustrated my device 10 as comprising a housing 12 having a bottom wall 14, sidewalls 16, 18, end walls 20, 22 and a cover 24 which fits down over the sidewalls. The cover 24 is provided with an upwardly facing, padded surface 26 upon which a person may comfortably rest an arm. As illustrated, the cover may be cut away or formed as indicated at 27 and the end wall 22 may be inclined upwardly and inwardly to provide a cavity in which a conventional electric switch 28 is located. The purpose of this switch will be discussed in detail hereinafter.
It will be appreciated that the device 10 may be as decorative as desired. The housing 12, including the cover 24, may be constructed from any suitable material, such as metal or plastic. The total length of the device 10 need not be much greater than the length of a person s forearm. The width of the device may be, for instance, 6 inches.
While I have illustrated the cover 24 as being arranged to slip down over the end wall and sidewalls 16, 18, it will be appreciated that the cover may be hingedly mounted in a conventional manner to swing upwardly.
Inside the housing 12, I provide an elongated platform 30 which my be gently oscillated by means of a conventional electric motor 32. In the illustrative embodiment, me motor 32 is mounted on the bottom I4 and its output shaft 34, which is bent is illustrated, extends upwardly therefrom. The platform 30 may be connected to the bent shaft 34 by means such as illustrated bearing 36. the inner race 38 of which is mounted on the upper end of the bent shaft and the outer race 40 of which is connected to the platform. I may provide means such as the illustrated spring means 42 extending between portions of the housing 12 and the platform 30 yieldably to hold the platform 30 in position. Further, I may provide means, such as the illustrated walls 31, 31' for confining the movement of the platform. Thus, because of the bend in the shaft 34, when the motor 32 is energized to drive the shaft in the direction of the arrow 44, the platform 30 is oscillated in all directions as indicated by the arrows 46, 48. I prefer that the motor 32 be a relatively low-speed motor so that this oscillation of the platform 30 will be gentle and smooth. The reason for gently oscillating the platform 30 is to mix thoroughly the blood drawn into the test tubes with the materials contained therein.
The platform 30 provides a longitudinally extending, square-walled trackway 50 and a pair of longitudinally and vertically extending sidewalls 52, 54, the sidewalls and the trackway providing a guideway for receiving a cartridge 56 (FIGS. 1 and 2) containing, in the illustrative embodiment, three evacuated blood test tubes 58, 60, 62, each of which is sealed with a conventional rubberlike stopper 58a, 60a, 62a. As illustrated in FIG. 2, the cartridge 56 may be provided with a guide strip 64 which is slidably received in the trackway 50 to guide the cartridge for movement along the platform 30.
I provide a pusher plate 68 which is arranged for reciprocation in the guideway provided by sidewalls 52, 54, the pusher plate being provided with a downwardly extending tang 70 which slidably engages the trackway 50. An internally threaded tube 72 extends rearwardly from the pusher plate 68 as illustrated. In order to drive the pusher plate 68, I provide a motor 74 which is mounted on the rear end of the platform 30 as illustrated, the motor 74 driving an externally threaded shaft 76 which threadedly engages the tube 72. Thus, when the motor 74 is energized to drive the shaft 76 in one direction, the pusher plate 68 moves in the direction of the arrow 78 and, when the motor 74 is energized to drive the shaft 76 in the opposite direction, the pusher plate 68 moves in the opposite direction.
There is an end member 80 at the forward end of the platform 30, this member being spaced apart from the forward ends 82, 84 of the guide walls 52, 54. In this space between the member 80 and the ends 82, 84 of the walls 52, 54, I can drop a manifold 86 from which extends three parallel and equally spaced apart hollow needles 88, 90, 92. The manifold 86 is formed with an internal passageway 94 which is in comm unication with the needles 88, 90, 92. A flexible plastic tube 96, preferably made from a hemorepellant material, connects the passageway 94 and, therefore, the needles 88, 90, 92, to a vein-puncturing needle 98. I prefer to provide a gripper on the vein-puncturing needle 98 as illustrated.
In the illustrative embodiments, each end of the manifold 86 is provided with a corner notch for receiving the end 82, 84 of the adjacent wall 52, 54. This is one scheme for holding the manifold 86 in a desired position relative to the platform 30.
In operation of the device 10, the nurse or technician responsible for taking blood specimens will remove the manifold 86 including the needles 88, 90, 92 from a sanitary package and place the manifold in its illustrated position on the platform 30. Then, the nurse or technician will drop a cartridge 56 into the guideway provided by the trackway 50 and the sidewalls 52, 54 with the stoppers 58a, 60a, 62a facing the needles 88, 90, 92. Preferably, as will be appreciated by those familiar with the use of evacuated test tubes, each of the needles 88, 90, 92 is coaxially aligned with the stopper 58a, 60a, 62:: through which the needle will penetrate. With the cartridge 56 and the manifold 86 in position, the nurse or technician will energize the motor 32 gently to oscillate the platform 30. Then, after the vein-puncturing needle 98 is inserted in to a vein, the motor 74 may be energized to drive the pusher plate 68 in the direction of the arrow 78 to cause the needles 88, 90, 92 to penetrate through, respectively, the stoppers 58a, 60a,
Referring now to FIG. 5, it will be seen that I have illustrated one device, indicated generally at 178, for sequentially depositing blood specimens into a plurality of tubes carried in a cartridge 146, The device 178 includes members 180, 182 for supporting the cartridge 146 for rotation about a journal axis extending parallel to the axes of the tubes carried in the cartridge and equidistantly spaced therefrom. It will be seen that, in the illustrative embodiment, each of the support members 180, 182 is provided with a triangularly shaped cutout for receiving and engaging an end portion of the cartridge 146. I have illustrated a rotary stepping drive motor 184 which is drivingly connected, by means indicated at 186, to the support member 180. This motor 184, when energized, is arranged to drive the member 180 and the cartridge 146 through 120 step movements about the axis defined by the members 180, 182. The means by which the members 180, 182 are mounted as well as the motor 184 and the transmission 186 may be conventional and need not be discussed, in detail, in this description.
The device 178 further comprises a block or a single channel manifold 188 which carries a single hollow needle 190 which is connected through a passageway in the block and a flexible tube 192 to a vein-puncturing needle 194. The block 188 may be a plastic block formed with the passageway providing communication between the needle 190 and the tube 192 in the same manner that the manifold 86 is formed. The needle 190 is preferably held so that it will extend toward the stoppers 154a sealing the tubes carried in the cartridge 146. Specifically, it is desirable that the needle 190 always be coaxially aligned with one of the tubes in the cartridge 146 carried by the support members 180, 182.
In order to drive the needle 190 sequentially to penetrate through the stopper 154a, I provide a drive motor 196 which may be drivingly connected to the block 188 by means such as the illustrated gear 198 and rack 200. Specifically, the block 188 is carried by the rack 200 and, when the motor 196 is driven in one direction, the needle 190 moves in the direction of the arrow 202 and, when the motor is driven the opposite direction, the needle 190 moves in the direction of the arrow 204.
Preferably, the motor 184, 196, rack 200 and supports 180, 182 are mounted upon an oscillable platform 30, only a fragment of which is shown.
Thus, in the use of the device 178, the nurse or technician taking the blood specimens will place the cartridge 146 in the support members 180, 182, place the block 188 in the proportioned cutout 206 in the rack 200 and, then, place the needle 194 into a vein. At that point, the motor for oscillating the platform 30 is energized and then the motor 196 is energized to move the needle 190 in the direction of the arrow 202 to penetrate the needle through the coaxially aligned stopper 154a. After a predetermined time, the motor 196 is again energized to move the needle 190 in the direction of the arrow 204 so that the motor 184 can be energized to rotate the cartridge 146 l to place another in coaxial alignment with the needle 190, and, thereafter, the needle 190 is again moved in the direction ofthe arrow 202 to deposit blood into the second coaxially aligned tube.
It will be appreciated that I may provide circuit means arranged sequentially to operate the indexing motor 184 and the drive motor 196 so that the nurse or technician taking the blood specimens need only throw one switch after the needle 194 is punctured into a vein. Preferably, during the entire blood-drawing operation, the platform 30 is being gently oscillated to oscillate the tubes in the cartridge 146.
The rack 200 constitutes means for rigidly holding the hollow needle 190 and the cartridge 146 comprises means for supporting a plurality of conventional evacuated test tubes. The motor 184 and transmission 186 and support member 180, 182 comprise indexing means for providing relative movement between the means which supports the needle 190 and the cartridge 146. The motor 196 and the transmission 198 comprise drive means for providing relative reciprocation 8 between the support means for the needle 190 and the cartridge 146.
Referring now to FIG. 6, it will be seen that I have illustrated another device, indicated generally at 210, for sequentially depositing blood into a plurality of test tubes. This device 210 comprises a support 212 upon which a cartridge 146' may be placed. In the illustrative embodiment, the support 212 provides a pair of spaced apart locating blocks 214, 216 which engage notches 218, formed in the edges of the cartridge 146' to prevent movement of the cartridge longitudinally, i.e., in the direction of the axes of the tubes in the cartridge, relative to the support 212. The illustrative support 212 is reciprocated longitudinally by a drivescrew 220 which is driven by a motor not shown.
It will be seen that I have illustrated a manifold or block 188' and a single hollow needle 190 and means for sequentially positioning the needle adjacent the stopper 154a of each of the tubes in the cartridge 146. Specifically, in the illustrative embodiment I provide a rotary-stepping motor 222 for moving a support 224 which holds the block 188 in a step-bystep manner. The motor 222 preferably moves the support 224 in 120 increments.
The cartridge 146 and the support 212 are proportioned and arranged so that one of the tubes in the cartridge 146 will he coaxially aligned with the needle 190' in each of its three positions obtained by energizing the motor 222. Thus, the support 224 moves about an axis which is parallel to and equidistantly spaced from the axes of the tubes in the cartridge 146.
The nurse or technician taking blood specimens using the device 210 places the cartridge 146 on the support 212 as illustrated and then places the block 188' in the proportioned cutout 226 in the support 224. Then, after the needle 194 is inserted into the vein, the nurse or technician may operate a switch to cause the support 212 to be driven toward the needle to penetrate the needle through the stopper 154a of the first tube in the cartridge 146. After a predetermined time the support 212 is moved away from the needle 190' and then the motor 222 is energized to index the needle so that is is in coaxial alignment with the second tube in the cartridge 146.
Again, the support 212, motor 222 and drivescrew 220 are preferably mounted on an oscillable platform 30, only a portion of which is shown.
In the device 178, the needle 190 is reciprocated axially toward and away from the stoppers of the tubes in the cartridge 146 and the cartridge is rotated about an axis in a stepby-step manner sequentially to position each stopper adjacent the needle. In the device 210, the tubes and the cartridge are reciprocated toward and away from the needle 190 and the needle is driven about an axis in a step-by-step manner sequentially to be positioned adjacent each of the stoppers.
Referring now to FIG. 7, it will be seen that I have illustrated still another device, indicated generally by the reference numeral 230, for sequentially depositing blood into a plurality of test tubes. The device 230 utilizes the cartridge 56 which contains three tubes as discussed previously. The cartridge 56 is placed upon a support 232 and held in position thereon by means such as the spring clip indicated at 234. The support 232 and the cartridge 56 supported thereon is moved in a step-by-step manner as indicated by the two arrows 235 by a motor 236. The motor 236 may be connected to the support 232 by means such as the illustrated drivescrew 238. The motor 236 is, therefore, indexing means for moving the cartridge 56 in a step-by-step manner sequentially to position the stopper of each tube contained in the cartridge adjacent a single hollow needle 190. The block 188 carrying the needle is placed in a cutout 239 on a support 240 which, in the illustrative embodiment, is drivingly connected to a motor 242 by a drivescrew 244. The motor 242 is a bidirectional motor used to reciprocate the needle 190' toward and away from the carthrough tridge 56 sequentially to penetrate the needle 190' the stoppers of the tubes contained in the cartridge.
62a. As soon as the needles 88, 90, 92 penetrate through the stoppers 58a, 60a, 62a, blood will be drawn from the vein through the needle 98, tube 96, passageway 94 and into the evacuated tubes 58, 60, 62.
It will be appreciated that the above-described method is such that the only action required by the nurse or the technician after the needle 98 is inserted into the vein and before the needle is withdrawn from the vein is to throw a switch which energizes the motor 74. The tube 96 is of sufficient length to permit the platform 30 to oscillate without, in any way, disturbing the position of the needle in a vein.
Thus, by using my device 10, a plurality of conventional evacuated test tubes, such as the three illustrated tubes 58, 60, 62 can be simultaneously at least partially filled with blood in a short period of time and without maneuvering the needle 98. Since the platform 30 can be oscillated before the needle 98 is inserted into the vein or, at least, before the motor 74 is energized, my device will begin to mix the blood drawn into the tubes 58, 60, 62 immediately with the material in the tubes. In fact, in order to assure such immediate mixing of the blood with the material in the tubes, I prefer to arrange my device 10 so that the motor 74 cannot be energized to drive the pusher plate 68 forward until the motor 32 is energized to oscillate the platform 30. As stated previously, this is an important object of my invention.
While I have illustrated three test tubes 58, 60, 62, it will be appreciated that the cartridge 56 may contain more or less tubes as desired. Generally, in most blood tests, it is only desired that three such tubes be at least partially filled with blood.
Referring now to FIG. la, an illustrative control system for my device 10 will be discussed. I show positive voltage terminals 102, 102' and negative voltage terminals 104, 104' providing power for my device 10. It will be appreciated that these terminals may represent the terminals of a battery power source or the output terminals of a conventional rectifier for alternating current. The motor 32 is energized by current flow through a manually operated switch 106, the coil of a relay 108 and the master switch 28. The relay 108, when energized, closes switch 110 through which the motor 74 is energized for rotation in a direction for driving the pusher plate 68 in the direction of the arrow 78. That is, current flows from the terminal 102, through the switch 28, switch 110, a switch 112, the coil of motor 74, a switch 114 and a switch 116 to the negative voltage terminal 104 to drive the motor 74 to move the plate 68 in the direction of the arrow 78.
Switches 112 and 116 are manually operated, double throw switches arranged, when thrown one way and switches 110 and 114 are closed, to drive motor 74 in one direction to advance plate 68 and, when thrown in the opposite way and switch 114 is closed, to drive motor 74 in the opposite direction to retract plate 68. Switch 114 is normally closed and is opened by a tang 115 in the plate 68 when the plate has moved a predetermined distance in the direction of the arrow 78. Switches 112 and 116 may be connected to a common actuator as illustrated.
It will be appreciated that the motor 74 cannot be energized to advance the plate 68 in the direction of the arrow 78 unless the switch 110 is closed and that the switch 110 will not be closed unless the motor 32 is energized to oscillate the platform 30.
Referring now to FIG. 2, it will be seen that the cartridge 56 is provided with three longitudinally extending, parallel openings 120, 122, 124 into which the tubes 58, 60, 62 are, respectively, inserted. The mouths of these openings 120, 122, 124 are proportioned and designed snugly to engage, respectively, the stoppers 58a, 60a, 62a so that, when the cartridge is pushed in the direction of the arrow 78 by the pusher plate 68, the force exerted by the needles 88, 90, 92 upon the stoppers will not be directed through the walls of the tubes 58, 60, 62. The further advantage of having the mouth of the openings 120, 122, 124 snugly engaging the stoppers 58a, 60a, 62a is that not all of the tubes which will be used with the cartridge will be of the same length.
I prefer to provide a cover 126 which slips over the end of the cartridge 56 as illustrated, this cover being provided with openings 120, 122, 124 which are in registry with the mouths of the correspondingly numbered openings in the cartridge. These openings 120, 122', 124 are provided to accommodate the needles 88, 90, 92.
It will be appreciated by those familiar with blood collecting methods that the test tubes 58, 60, 62, after they are at least partially filled with blood, are conventionally inserted into a plastic mailing package. Thus, my cartridge 56, which is usable with the device 10 in the blood-drawing operation, can be used also as a mailing package.
Referring now to FIG. 3, it will be seen that l have illustrated a generally triangularly shaped cartridge having an open end 132 through which three conventional evacuated tubes are inserted. Inside the cartridge, there are three triangularly related wall sections 134, 136, 138 providing cubicles for receiving the closed ends of the tubes which are inserted into the cartridge. A centrally located, longitudinally extending stem 140 is arranged to extend from the intersection of the wall sections 134, 136, 138 to the open end 132 of the cartridge 130. The stem 140 separates the tubes which are inserted into the cartridge 130. The end of this stem 140 which is adjacent the open end 132 is proportioned and designed so that, when three tubes are inserted into the cartridge 130, the stoppers sealing the tubes are engaged snugly by portions of the perimeter of the open end 132 of the cartridge and by the adjacent end of the stem 140.
Referring now to FIG. 4, it will be seen that l have illustrated another generally triangularly shaped cartridge 146 which provides a plurality of openings 148, 150, 152 which receive, respectively, conventional evacuated tubes, such as indicated at 154. The openings 148, 150, 152 are also triangularly arranged so that, when tubes are, respectively, received therein, the axes of the tubes will extend through the corners of an equilateral triangle. The reason for this will become apparent as this description progresses.
For use with the generally triangularly shaped cartridges 130, 146, I provide a generally triangularly shaped manifold 156 from which extends hollow needles 158, 160, 162, the manifold being provided with a passageway 164 in communication with the needles. This passageway 164 is connected by means of a flexible tube 166 to a vein-puncturing needle 168. The needles 158, 160, 162 are triangularly arranged so that each needle can be coaxially aligned with one of the openings 148, 150, 152 to be penetrated through the stopper of the tube disposed in the opening.
Thus, the manifold 156 and either one of the cartridges 130, 146 may be used with my device 10.
For aesthetic reasons, I may provide a paper liner which can be fitted into the open end of the cartridge 146 so that, when the manifold 156 is pulled away from the cartridge, the blood drops on the needles 158, 160, 162 will drop into and be absorbed by the liner 170. Of course, this liner 170, the manifold 156, tube 166 and needle 168 may be conventionally disposed of after the blood is deposited into the tubes carried in the cartridge 146.
The cartridges shown in FIGS. 2, 3 and 4 may be used with my device 10 simultaneously to deposit blood into the tubes disposed in the cartridges. Further, these same cartridges may be used with other embodiments of my invention which sequentially deposit blood into the tubes contained in the cartridge as will be hereinafter described.
The triangularly shaped cartridges 130, 146 may be preferable in some cases because they will stand alone on their bases, i.e., on their closed ends, to provide a self-standing unit with which the laboratory technicians can work. Further, for the same amount of material, a triangularly shaped cartridge may be somewhat stronger than a rectangularly shaped cartridge. Further, as will be discussed in conjunction with FIGS. 5-8, as a matter of mechanics, it may be advisable to index or position the triangularly shaped cartridges 130, 146 about a longitudinal axis.
Again, the support 232, 240, 242 and the motor 236 are preferably mounted on an oscillable platform 30, only a portion ofwhich is shown.
Referring now to FIG. 8, it will be seen that I have illustrated still another device 250 comprising a guideway 252 for slidably receiving a cartridge 56 and means 254 for drivingly connecting the cartridge to an illustrative drivescrew arrangement 256. The drivescrew arrangement is provided for reciprocating the cartridge 56 in the guideway 252 as indicated by the arrows 258, 260 sequentially to push the stoppers of the tubes contained in the cartridge onto a single needle 190'.
The block 188' carrying the single needle 190' is disposed in a socket indicated at 262 provided in a support member 264 which is reciprocated in a step-by-step manner by a solenoid 266. The solenoid 266 is connected to the support member 264 by means of a connecting device 268. The device 268 comprises a pivotally mounted hook 270 which is arranged to engage notches 272, 274 provided on the support member 264. A spring 276 is arranged yieldably to engage the hook with the notches. The solenoid 266 comprises a plunger 278 which extends through an opening in the device 268, the distal end of the plunger 278 being provided with an enlarged end 280 which serves loosely to connect the end of the plunger to the device 268. A spring 282 is arranged conventionally to urge the plunger 278 to its outermost position in the solenoid 266. I have illustrated a trip release 284 for manually disengaging the hook 270 from the notches 272, 274 and a spring 286 for biasing the support member 264 to its illustrated positron.
The connecting device 268 is mounted for slidable movement relative to the support member 264 within the limits established by the elongated slots 288. Assuming that the illustrated position of the support member 264 is its initial starting position and that the needle 190 has been penetrated through the opening 120' of the cartridge 56 and the stopper of the tube aligned with that opening and that it is desired to move the needle 190' into alignment with the opening 122, this movement is accomplished by energizing the solenoid 266 while the hook 270 is engaged with the notch 272 to move the needle 190' one step as indicated by the arrow 290. Then the cartridge 56 is driven in the direction of the arrow 258 to push the stopper of the tube aligned with the opening 122' upon the needle 190. While the needle 190 is extending through the stopper behind the opening 122, the solenoid 266 is deenergized and the spring 282 moves the connecting device 268 to the left as viewed in FIG. 8 and relative to the support member 264 to engage the hook 270 with the notch 274. Then, after the cartridge 56 is pulled in the direction of the arrow 260, the solenoid 266 may again be energized to move the needle 190 one step as indicated by the arrow 292 to position the needle 190' in alignment with the opening 124. When the needle 190' is aligned with the opening 124, the cartridge 56 can be pushed in the direction of the arrow 258 to penetrate the needle through the stopper of the tube in alignment with the opening 124. When the blood is deposited into the tube in alignment with the opening 124', the blood-collecting operation is completed and while the needle 190' is still penetrating through the stopper of the tube aligned with the opening 124', the cartridge 56 with the needle and block 188 connected thereto can be lifted out of the guideway 252. Then, the supporting member 264 can be returned to its initial starting position by pushing down on the trip 284 which disengages the hook 270 from the notch 274.
It will be appreciated that, in each of the devices 178, 210, 230, 250, I may use a solenoid for driving the single needle 190 through the stopper of each of the tubes in the cartridges 146, 56.
In order to prevent the blood which is contained in the needle 194, tube 192 and block 188 from running out the open end of the needle 194 after it is removed from a vein, I prefer to leave the needle 190 penetrating into the last three test tubes into which the needle is inserted. After the person from Whom the blood specimens have been taken leaves the area, the nurse or technician taking the blood can remove the needle from the last ofthe three tubes which is filled and then deposit the needle, block 188, flexible tube 192 and needle 194 into a trash container.
Referring now to FIG. 9, it will be seen that I have illustrated a chuck means 300 for releasably, but rigidly holding a hollow needle 302 so that stoppers of evacuated tubes can be pushed upon the needle, the needle being connected by means ofa flexible tube 304 to a vein puncturing needle (not shown).
The illustrative chuck means 300 includes a member 306 providing a surface 306a having a trough 308 formed therein for receiving the needle 302, a second member 310 providing a second surface 310a for engaging the first-mentioned surface 306a, means 312 for hingedly connecting the members 306, 310 so that the surfaces 306a and 310a can be separated, and fastener means 314 for releasably holding the surfaces in engagement. The illustrative fastener means 314 includes a wing screw 316 which is conventionally rotatable to bridge across a notch 318 provided in the member 310.
In some cases, it may be sufficient to provide a resilient pad, such as indicated at 320, on the surface 310a, which pad resiliently engages the needle 302 securely to position the needle in the trough 308 of the chuck means 300. In other cases, it may be desirable to provide a small plastic block, such as indicated at 322, which is molded so as to be rigidly connected to the needle 302 and which is received in a recess 324 formed in the surface 306a. It will be appreciated that the engagement of the block 322 with the recess 324 will, when the surfaces 306a and 310a are brought into engagement, position when needle 302 against longitudinal movement.
Thus, a nurse or technician using the chuck means 300 may simply raise the upper member 310 and insert a needle 302 into the trough 308 as indicated by the arrows 326 and then, close the chuck means by lowering the upper member 310 and operating the fastener means 314.
It will be appreciated that, by using the chuck means 300, it will be possible to eliminate the block 188, 188 shown in FIGS. 58, the block being a plastic piece of material having a passageway formed therein with a flexible tube connected to one end of the passageway and a needle extending into and connected to the other end of the passageway. The formation of such a block will be significantly more expensive than the connection of the needle 302 to one end of the flexible tube 304. While I have illustrated (FIG. 9) the small block 322 molded about the end of the flexible tube receiving the hollow needle 302, as stated above, I may provide chuck means 300 which will resiliently and frictionally engage the needle and hold the needle rigidly without using such a block. In such a case, the flexible tube 304 may be simply heat sealed to the needle 302.
My illustrative chuck means 300 may be used in any one of the systems illustrated in FIGS. 5-8. That is, the chuck means 300 may be placed on the rack 200 (FIG. 5), on the support member 224 (FIG. 6), on the support member 240 (FIG. 7), or on the support member 264 (FIG. 8).
Referring now to FIG. 10, it will be seen that I have shown an illustrative chuck means 300 mounted on a support block 330 for reciprocation in the direction of the arrow 332 which is parallel to the longitudinal axis of the needle 302 held in the chuck. The illustrative chuck means 300 includes an illustrative snap fastener 334 in lieu of the rotatable-type fastener means 314 discussed above.
The support member 330 is formed with an upwardly opening, longitudinally extending cavity 336 for receiving a conventional evacuated tube 338, the end of the cavity 336 facing the chuck means 300 being enlarged as indicated at 340 to receive the stopper 338a sealing such a tube. The tube 338 may be dropped into the cavity 336 and then the chuck means 300' may be pushed manually toward the tube to penetrate the needle 302 carried by the chuck means through the stopper 3380. After blood is drawn into the evacuated tube 338, the chuck means can be pulled away from the cavity 336 and the tube can be removed from the cavity and a second tube can be placed therein. The device of FIG. 10, therefore, is a manual means for sequentially penetrating the needle 302, which is connected by a flexible tube 304 to a vein-puncturing needle, through the stoppers of several evacuated tubes.
In order to facilitate the manual removal of the tubes 338 from the cavity 336, I provide enlarged, laterally extending openings 342 intermediate the ends of the cavity. These openings 342 will permit a nurse or technician to grip the tube securely at a point intermediate its ends.
Referring now to FIG. 11, it will be seen that I have illustrated a chuck means 300' for releasably and rigidly holding a hollow needle 302 and means 344 for reciprocating the chuck means toward and away from the stoppers of a plurality of tubes. The illustrative means 344 includes a bidirectional drive motor 346 and drivescrew arrangement 348 for reciprocating the chuck means 300 as indicated by the arrow 350.
In FIG. I l the tubes 352 are carried by a cartridge belt 354, i.e., a belt formed with a plurality of spaced apart loops 356, each of which receives a tube 352. Each loop 356 of the belt 354 is preferably provided with coded indicia for identifying the tube received therein. Preferably, means such as the illustrated knife 358 which is pivotally mounted as indicated at 360, will be provided for separating the belt loops 356. In the illustrative embodiment, the knife 358 is pivotally mounted on the same member as the chuck means 300 so that when the chuck means is moved away from the tubes, the knife will drop down to separate the loop 356 from the belt 354. In some cases, it may be advisable to remove or to deactivate the knife 358 so that reciprocation of chuck means 300 will not separate belt loops.
In the illustrative embodiment, there is a frame 362 defining a guideway through which the belt 354 and tubes 352 move. At one point on the frame 362, there is provided a notch 364 through which the needle 302 reciprocates. Means must be provided for driving the belt 354 in a step-by-step manner past the notch 364. In the illustrative embodiment, this function is provided by a rotary stepping motor 366 which drives a drive wheel 368 which engages the belt 354. The drive wheel 368 may be soft so as resiliently to engage the belt 354 as illustrated. Preferably, each step of the motor 366 moves the belt 354 one loop space sequentially to advance each tube 352 carried by the belt past the notch 364.
The system of FIG. 11 may be ideally used for collecting large groups of blood specimens from large groups of people, such as Army inductees. The coded indicia or serial numbers carried on each loop 356 will facilitate the identification of each blood specimen. That is, each person from whom blood is to be taken can be assigned a serial number corresponding to the number of the loop 356 receiving the tube 352 into which the persons blood is deposited. Thus, using the system of FIG. 11, one or more blood specimens can be efficiently taken from each person of a group of people. The nurse or technician taking the specimens will not have to manipulate manually the tubes.
The rotary stepping motor 366 and drive wheel 368 constitute indexing means for advancing the tubes 352 or the belt 354 holding the tubes sequentially past the chuck means 300 which holds the needles to be penetrated through the stoppers of the tubes.
Referring now to FIG. 12, it will be seen that I have shown a block 188 carrying a needle 190, the block being mounted on a platform 30'. The hollow needle 190 is connected by means of a flexible tube 192 to a vein-puncturing needle. The block 188 is illustrative and chuck means 300 may be used in lieu thereof.
The system of FIG. 12 includes a chamber 382 in which tubes 384 are held for movement toward and away from the needle 190. In the illustrative embodiment, the chamber 382 is reciprocated toward and away from the needle 190 by means of a bidirectional motor 384 and drivescrew 386 arrangement. The system of FIG. 12 also includes cartridge means or a hopper 388 for sequentially feeding such tubes 384 into the chamber 382 and means 390 for ejecting filled tubes from the chamber so that empty tubes can be deposited therein. In the illustrative embodiment, the ejecting means 390 comprises a member 392 mounted for pivotal movement as indicated at 394 toward and away from the chamber 382 as indicated by the arrow 395. The member 392 provides a portion 396 for engaging a tube 384 and pushing it out of the chamber 382. The ejecting means 390 also includes a second member 398 which is pivotally mounted on a platform 400 so as to engage a portion 402 of the member 392 when the chamber 382 is moved away from the needle I toward the cartridge means 388. The member 398 is pivotally movable as indicated by the arrow 404 and a leaf spring 406 is provided for yieldably urging the member 398 in a direction opposite to the arrow 404.
In the operation of the system of FIG. 12, when the chamber 382 with a tube 384 is moved away from the needle I90 toward the cartridge means 388, the member 392 strikes the member 398 and moves inwardly to push the tube out of the chamber as indicated by the arrow 408. The chamber 382 continues to move to a position under the cartridge means 388 so that another tube 384 can drop into the chamber for movement toward the needle 190. The spring 406 will permit the member 398 to pivot in the direction of the arrow 404 when the member 392 is moved toward the needle 190.
It will be appreciated that the entire system of FIG. 12 may be mounted on an oscillable platform 30', only a portion of which is shown.
What is claimed is:
l. A blood collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, flexible tube means for connecting said needle means to said vein-puncturing needle, said holding means being arranged to hold such tubes so that such stoppers face said needle means, drive means for providing relative reciprocation between said needle means and said holding means to cause said needle means to penetrate through such stoppers, and means for gently oscil lating said holding means and such tubes held thereby.
2. The device of claim I in which said drive means is electrically operated and including circuit means for preventing energization of said drive means unless said holding means is oscillating.
3. A blood collecting device comprising a manifold providing a passageway, a plurality of hollow needles carried by said manifold and communicating with said passageway, each of said hollow needles having a sharpened end portion extending away from said manifold, a vein-puncturing hollow needle, flexible tube means for connecting said vein-puncturing needle to said passageway, frame means for holding a plurality of conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, said frame means being arranged to hold each such tube in a position so that its stopper is facing the sharpened end portion of one of said first-mentioned needles, drive means for providing relative reciprocation between said manifold and said frame means to cause the sharpened end portions of said first-mentioned needles simultaneously and respectively to penetrate through said stoppers and into said tubes, and means for gently oscillating said frame means and such tubes held thereby.
4. The device of claim 3 in which said drive means is electrically operated.
5. The device of claim 4 in which said oscillating means is electrically operated and including circuit means for assuring that said oscillating means is energized before said drive means can be energized.
6. A blood collecting device comprising a manifold providing a passageway, a plurality of hollow needles carried by said manifold and communicating with said passageway, each of said hollow needles having a sharpened end portion extending away from said manifold, a vein-puncturing hollow needle, flexible tube means for connecting said vein-puncturing needle to said passageway, frame means for holding a plurality of conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, said frame means being arranged to hold each such tube in a position so that its stopper is facing the sharpened end portion of one of said first-mentioned needles, drive means for providing relative reciprocation between said manifold and said frame means to cause the sharpened end portions of said first-men tioned needles simultaneously and respectively to penetrate through said stoppers and into said tubes, a platform upon which said frame means, manifold, and drive means are mounted, and means for gently oscillating said platform.
7. The device of claim 6 in which said platform provides a guideway for reciprocably mounting sad frame means and in which said drive means is arranged to move said frame means along sad guideway toward said manifold.
8. The device of claim 6 in which said oscillating means includes a motor, a bent shaft driven by said motor, and a bearing for coupling said platform to said shaft, said bearing having an outer race upon which said platform is mounted and an inner race mounted on said shaft.
9. A blood collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, flexible tube means for connecting said needle means to said vein-puncturing needle, said holding means being arranged to hold such tubes so that such stoppers face said needle means, power means for providing relative reciprocation between said needle means and said holding means to cause said needle means to penetrate through such stoppers, and means for gently oscillating said holding means and such tubes held thereby.
10. The device of claim 1 in which said needle means includes a second hollow needle and means for rigidly holding said second needle, and including indexing means for providing relative movement between said holding means and said second needle, said indexing means being arranged so that the stoppers of such tubes are sequentially disposed adjacent said second needle to be penetrated thereby.
11. A blood specimen collecting device comprising a veinpuncturing hollow needle, means for supporting a plurality of test tubes, each such tube being closed by sealing means disposed in the end thereof, hollow needle means, means for penetrating said hollow needle means through such sealing means and into such tubes, said penetrating means including power means for providing relative reciprocation between said hollow needle means and said supporting means, and means for gently oscillating said supporting means and the tubes supported thereby.
12. The device of claim 11 in which said hollow needle means includes a second hollow needle, and in which said penetrating means includes indexing means for providing relative movement between said supporting means and said second hollow needle, said indexing means being arranged so that the sealing means of such tubes are sequentially disposed adjacent said second needle to be penetrated thereby.

Claims (12)

1. A blood collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a veinpuncturing hollow needle, flexible tube means for connecting said needle means to said vein-puncturing needle, said holding means being arranged to hold such tubes so that such stoppers face said needle means, drive means for providing relative reciprocation between said needle means and said holding means to cause said needle means to penetrate through such stoppers, and means for gently oscillating said holding means and such tubes held thereby.
2. The device of claim 1 in which said drive means is electrically operated and including circuit means for preventing energization of said drive means unless said holding means is oscillating.
3. A blood collecting device comprising a manifold providing a passageway, a plurality of hollow needles carried by said manifold and communicating with said passageway, each of said hollow needles having a sharpened end portion extending away from said manifold, a vein-puncturing hollow needle, flexible tube means for connecting said vein-puncturing needle to said passageway, frame means for holding a plurality of conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, said frame means being arranged to hold each such tube in a position so that its stopper is facing the sharpened end portion of one of said first-mentioned needles, drive means for providing relative reciprocation between said manifold and said frame means to cause the sharpened end portions of said first-mentioned needles simultaneously and respectively to penetrate through said stoppErs and into said tubes, and means for gently oscillating said frame means and such tubes held thereby.
4. The device of claim 3 in which said drive means is electrically operated.
5. The device of claim 4 in which said oscillating means is electrically operated and including circuit means for assuring that said oscillating means is energized before said drive means can be energized.
6. A blood collecting device comprising a manifold providing a passageway, a plurality of hollow needles carried by said manifold and communicating with said passageway, each of said hollow needles having a sharpened end portion extending away from said manifold, a vein-puncturing hollow needle, flexible tube means for connecting said vein-puncturing needle to said passageway, frame means for holding a plurality of conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, said frame means being arranged to hold each such tube in a position so that its stopper is facing the sharpened end portion of one of said first-mentioned needles, drive means for providing relative reciprocation between said manifold and said frame means to cause the sharpened end portions of said first-mentioned needles simultaneously and respectively to penetrate through said stoppers and into said tubes, a platform upon which said frame means, manifold, and drive means are mounted, and means for gently oscillating said platform.
7. The device of claim 6 in which said platform provides a guideway for reciprocably mounting sad frame means and in which said drive means is arranged to move said frame means along sad guideway toward said manifold.
8. The device of claim 6 in which said oscillating means includes a motor, a bent shaft driven by said motor, and a bearing for coupling said platform to said shaft, said bearing having an outer race upon which said platform is mounted and an inner race mounted on said shaft.
9. A blood collecting device comprising means for holding conventional evacuated test tubes, each such tube being sealed with a conventional rubberlike stopper, hollow needle means for penetrating through such stoppers and into such tubes, a vein-puncturing hollow needle, flexible tube means for connecting said needle means to said vein-puncturing needle, said holding means being arranged to hold such tubes so that such stoppers face said needle means, power means for providing relative reciprocation between said needle means and said holding means to cause said needle means to penetrate through such stoppers, and means for gently oscillating said holding means and such tubes held thereby.
10. The device of claim 1 in which said needle means includes a second hollow needle and means for rigidly holding said second needle, and including indexing means for providing relative movement between said holding means and said second needle, said indexing means being arranged so that the stoppers of such tubes are sequentially disposed adjacent said second needle to be penetrated thereby.
11. A blood specimen collecting device comprising a vein-puncturing hollow needle, means for supporting a plurality of test tubes, each such tube being closed by sealing means disposed in the end thereof, hollow needle means, means for penetrating said hollow needle means through such sealing means and into such tubes, said penetrating means including power means for providing relative reciprocation between said hollow needle means and said supporting means, and means for gently oscillating said supporting means and the tubes supported thereby.
12. The device of claim 11 in which said hollow needle means includes a second hollow needle, and in which said penetrating means includes indexing means for providing relative movement between said supporting means and said second hollow needle, said indexing means being arranged so that the sealing means of such tubes are sequentially disposed adjacent said second needle to be penetrated thereby.
US824977A 1969-05-15 1969-05-15 Blood collecting method and device Expired - Lifetime US3633566A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
US824977A US3633566A (en) 1969-05-15 1969-05-15 Blood collecting method and device
CA080659A CA926718A (en) 1969-05-15 1970-04-21 Blood collecting method and device
SE05874/70A SE354962B (en) 1969-05-15 1970-04-28
GB2174370A GB1313331A (en) 1969-05-15 1970-05-06 Blood collecting method and device
DE19702022116 DE2022116A1 (en) 1969-05-15 1970-05-06 Method and device for taking blood samples
FR7017413A FR2047706A5 (en) 1969-05-15 1970-05-13
BE750378D BE750378A (en) 1969-05-15 1970-05-13 BLOOD COLLECTION METHOD AND DEVICE
NL7007075A NL7007075A (en) 1969-05-15 1970-05-15
US00205941A US3765402A (en) 1969-05-15 1971-12-08 Blood specimen collecting system

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US00205941A Expired - Lifetime US3765402A (en) 1969-05-15 1971-12-08 Blood specimen collecting system

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BE (1) BE750378A (en)
CA (1) CA926718A (en)
DE (1) DE2022116A1 (en)
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GB (1) GB1313331A (en)
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SE (1) SE354962B (en)

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WO1988006261A1 (en) * 1987-02-12 1988-08-25 Ab Carl Munters Method and device for conditioning of a gas
WO1988007351A1 (en) * 1987-03-23 1988-10-06 Joseph Parsons Nominees Pty. Ltd. Collection tube with pre-collection evacuator
US4784157A (en) * 1986-02-04 1988-11-15 Halls Justin A T Method and apparatus for taking samples from or administering medication to a patient
US4923449A (en) * 1986-11-19 1990-05-08 Kabushiki Kaisha Tiyoda Seisakusho Apparatus for collecting constant amounts of blood from individual donors
US4942881A (en) * 1988-04-26 1990-07-24 Al Sioufi Habib IV needle holder
US4995402A (en) * 1988-10-12 1991-02-26 Thorne, Smith, Astill Technologies, Inc. Medical droplet whole blood and like monitoring
US5127531A (en) * 1989-05-19 1992-07-07 Terumo Kabushiki Kaisha Fluid sample tube stand with holder support mechanism
US5330439A (en) * 1992-04-08 1994-07-19 American National Red Cross Safety device for use in collecting fluid samples
US6126609A (en) * 1998-11-23 2000-10-03 Keith & Rumph Inventors, Inc. Apparatus for taking blood samples from a patient
KR100343767B1 (en) * 2000-01-19 2002-07-20 녹십자의료공업주식회사 A Blood vessel connecter attached gathering machine of blood inspection for cell separate operation
GB2375053A (en) * 1997-12-04 2002-11-06 Agilent Technologies Inc A cartridge for sampling blood
US20100201120A1 (en) * 2009-02-10 2010-08-12 Daniel Mark Bolivar Rotating union
US20120130415A1 (en) * 2010-11-15 2012-05-24 Vascular Insights Llc Vascular treatment device
US20190282151A1 (en) * 2018-03-19 2019-09-19 Board Of Regents, The University Of Texas System Systems and methods for mixing drawn fluids
US10463388B2 (en) 2006-09-13 2019-11-05 Merit Medical Systems, Inc. Wire and device for vascular treatment

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US4661319A (en) * 1984-04-06 1987-04-28 Boehringer Mannheim Diagnostics, Inc. Blood transfer assembly
IT1189568B (en) * 1986-06-17 1988-02-04 Finbiomedica Srl DEVICE FOR THE COLLECTION IN THE VEIN OF BLOOD SAMPLES TO BE ANALYZED IN THE LABORATORY
CN1030352A (en) * 1987-07-09 1989-01-18 Avl股份公司 Measure the method and apparatus of parameters of interest in the live organism
AT397610B (en) * 1990-06-01 1994-05-25 Avl Verbrennungskraft Messtech DEVICE FOR TAKING BODY LIQUIDS
FR2665892B1 (en) * 1990-08-20 1994-10-28 Cogema APPARATUS FOR DRAINING AND RINSING NON-RECOVERABLE BOTTLES CONTAINING A TOXIC PRODUCT.
US5785662A (en) * 1996-05-30 1998-07-28 Medisys Technologies, Inc. Blood collection assembly with plurality of vials
US6626863B1 (en) 2000-11-22 2003-09-30 Nusaf, L.L.C. Safety syringe
CN101496725B (en) * 2008-01-30 2010-10-20 广州阳普医疗科技股份有限公司 Automatic blood sampling system and blood sampling device
WO2020102174A1 (en) * 2018-11-13 2020-05-22 Becton, Dickinson And Company Blood collection system and automatic blood collection device

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Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784157A (en) * 1986-02-04 1988-11-15 Halls Justin A T Method and apparatus for taking samples from or administering medication to a patient
US4923449A (en) * 1986-11-19 1990-05-08 Kabushiki Kaisha Tiyoda Seisakusho Apparatus for collecting constant amounts of blood from individual donors
WO1988006261A1 (en) * 1987-02-12 1988-08-25 Ab Carl Munters Method and device for conditioning of a gas
WO1988007351A1 (en) * 1987-03-23 1988-10-06 Joseph Parsons Nominees Pty. Ltd. Collection tube with pre-collection evacuator
US4942881A (en) * 1988-04-26 1990-07-24 Al Sioufi Habib IV needle holder
US4995402A (en) * 1988-10-12 1991-02-26 Thorne, Smith, Astill Technologies, Inc. Medical droplet whole blood and like monitoring
US5127531A (en) * 1989-05-19 1992-07-07 Terumo Kabushiki Kaisha Fluid sample tube stand with holder support mechanism
US5330439A (en) * 1992-04-08 1994-07-19 American National Red Cross Safety device for use in collecting fluid samples
GB2375053A (en) * 1997-12-04 2002-11-06 Agilent Technologies Inc A cartridge for sampling blood
GB2375053B (en) * 1997-12-04 2002-12-24 Agilent Technologies Inc A blood sampling cartridge
US6126609A (en) * 1998-11-23 2000-10-03 Keith & Rumph Inventors, Inc. Apparatus for taking blood samples from a patient
KR100343767B1 (en) * 2000-01-19 2002-07-20 녹십자의료공업주식회사 A Blood vessel connecter attached gathering machine of blood inspection for cell separate operation
US10463388B2 (en) 2006-09-13 2019-11-05 Merit Medical Systems, Inc. Wire and device for vascular treatment
US11903608B2 (en) 2006-09-13 2024-02-20 Merit Medical Systems, Inc. Wire and device for vascular treatment
US20100201120A1 (en) * 2009-02-10 2010-08-12 Daniel Mark Bolivar Rotating union
US8181996B2 (en) 2009-02-10 2012-05-22 Nova Scotia Community College Rotating union
US9375216B2 (en) 2010-11-15 2016-06-28 Vascular Insights, Llc Direction reversing vascular treatment device
US9585667B2 (en) * 2010-11-15 2017-03-07 Vascular Insights Llc Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein
US20120130415A1 (en) * 2010-11-15 2012-05-24 Vascular Insights Llc Vascular treatment device
US11241250B2 (en) 2010-11-15 2022-02-08 Merit Medical Systems, Inc. Vascular treatment devices and methods
US20190282151A1 (en) * 2018-03-19 2019-09-19 Board Of Regents, The University Of Texas System Systems and methods for mixing drawn fluids
US11690545B2 (en) * 2018-03-19 2023-07-04 Board Of Regents, The University Of Texas System Systems and methods for mixing drawn fluids

Also Published As

Publication number Publication date
US3765402A (en) 1973-10-16
SE354962B (en) 1973-04-02
GB1313331A (en) 1973-04-11
CA926718A (en) 1973-05-22
BE750378A (en) 1970-10-16
FR2047706A5 (en) 1971-03-12
NL7007075A (en) 1970-11-17
DE2022116A1 (en) 1970-11-26

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