US3599629A - Oxidized surface biopotential skin electrode - Google Patents

Oxidized surface biopotential skin electrode Download PDF

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US3599629A
US3599629A US3599629DA US3599629A US 3599629 A US3599629 A US 3599629A US 3599629D A US3599629D A US 3599629DA US 3599629 A US3599629 A US 3599629A
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electrode
concavity
defined
surface
skin
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Edwin Gordy
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Lexington Instr
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/04Measuring bioelectric signals of the body or parts thereof
    • A61B5/0402Electrocardiography, i.e. ECG
    • A61B5/0408Electrodes specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/04Measuring bioelectric signals of the body or parts thereof
    • A61B5/0402Electrocardiography, i.e. ECG
    • A61B5/04026Means for providing electrolyte, e.g. syringes

Abstract

An electrode adapted to be attached to the skin of an individual for obtaining a biological or physiological potential such as are associated with muscle activity or functions of the brain, the electrode being formed of a deformable, synthetic polymeric, electrically insulating material coated with a thin film of metallic silver having a surface layer that has been converted to silver chloride. One surface defines a concavity, a pair of holes joining the concavity to the opposite surface of the electrode. A female socket is molded as an integral part of the electrode so that the silver-silver chloride layer provides a continuous electrical pathway between the concavity and the socket.

Description

United States Patent 2,943,627 7/1960 Howell 3,151,619 10/1964 Sullivan Edwin Gordy Newtonville, Mass.

Aug. 28, 1968 Aug. 17, 1971 Lexington Instruments v Waltham, Mass.

lnventor Appl. No. Filed Patented Assignee OXIDIZED SURFACE BIOPQTENTIAL SKIN ELECTRODE 11 Claims, 3 Drawing Figs.

[1.8. CI 128/2.06 E Int. Cl A611 5/04 Field of Search 128/206,

References Cited UNITED STATES PATENTS 3,170,459 2/1965 Phipps et a]. 128/206 3,187,745 6/1965 Baum et a1. 128/206 3,337,608 6/1968 Figar 123/206 3,464,404 9/1969 Mason 128/206 Primary Examiner-William E. Kamm Attorney-Robert J. Schiller ABSTRACT: An electrode adapted to be attached to the skin of an individual for obtaining a biological or physiological potential such as are associated with muscle activity or functions of the brain, the electrode being formed of a deformable, synthetic polymeric, electrically insulating material coated with a thin film of metallic silver having a surface layer that V has been converted to silver chloride. One surface defines a concavity, a pair of holes joining the concavity to the opposite surface of the electrode. A female socket is molded as an integral part of the electrode so that the silver-silver chloride layer provides a continuous electrical pathway between the concavity and the socket.

PATENTEDAUGI mu 3.599.629

EDW/IV 60/70) INVENTOR.

RMQMLN ATTORNEY.

This invention relates to electrodes and more particularly to biopotential skin electrodes suitable for obtaining biological or physiological potentials such as are associated with muscular activity or neurological functions of the brain.

.As known, such potentials can be picked up at the skin of the patient and recorded by an electronic instrument such as an electromyograph, typically an electrocardiograph if current and voltage waveforms associated with the action of the heart are to be measured, or an electroencephalograph if brain voltages are to be recorded.

There long has been a need for a biopotential skin electrode combining low cost with high quality performance. Heretofore, biopotential electrodes providing satisfactory performance have been expensive,.whilst less costly electrodes have generally shown a poor response, particularly high DC drift and undue sensitivity to motion artifacts.

Accordingly, the present invention has as a primary object, the provision of a high quality, yet inexpensive and therefore throwaway" electrode for use with conventional biopotential measuring and recording instruments. Other objects are to provide such-an electrode which exhibits low sensitivity to motion artifacts; to provide such an electrode which can be easily attached to and removed from the skin of a patient and which can be used with conventional electrocardiograph electrolyte jellies or the like; to provide such an electrode which can be attached to the skin for extended periods of time short con-.

cern for irritation of the skin to which it is releasably affixed, and which because of its low cost can be discarded after a single use or re -used as desired.

These and other objects are achieved by a generally waferlike electrode of deformable, electrically insulating materials,

a portion of the electrode defining a concavity intended to be disposed adjacent the skin of the patient as by an electrically nonconductive pressure-sensitive adhesive. A pair of continuous passageways extend from the interior of the cavity through the electrode to an opposite surface. Also provided is at least one socket, adapted to connect with a terminal on a lead from the biopotential measuring instrument; A thin electrically conductive coatingon the electrode provides a continuous electrical path from the interior of the cavity to thevinterior of the socket. After the electrode is attached to the skin of a patient, it is made operative by connecting the terminal to a corresponding socket, then introducing an appropriate electrolyte through one of the passageways into the cavity so as to form a conductive path between the skin and the coating on the interior of the cavity. The coating is selected so that it forms a stable contact potential both with the terminal and with-the conductive electrolyte.

Other objects of the invention will in part be obvious and will in part appear hereinafter. The invention accordingly comprises the apparatus possessing the construction, combination of elements, and arrangement of parts which are exemplified in the following detailed disclosure, and the scope of the application of which will be indicated in the claims.

For a fullerunderstanding of the nature and objects of the present invention, reference should be had to the following detailed description taken in connection with the accompanying drawing, wherein:

FIG. 1 is an exploded, perspective view of the invention;

FIG. 2 is a cross-sectional view taken centrally across an assembled embodiment of FIG. 1; and

FIG. 3 is a perspective view of a variation of the embodiment ofFlG. 1.

Referring now to FIGS. l and 2, there is shown an electrode, comprising a generally flat wafer of disc 22. Also included, as means for attaching disc 22 to the skin of a subject is a contact sheet 24. Disc 22 is formed of a mechanically deformable, electrically insulating material such as a synthetic polymeric plastic or the like; polypropylene, for example. At

least one surface of the disc is characterized by having at least one concavity 26 therein. Concavity 26 need not be of a regular shape and need cover only a small portion of one surface of 'the disc. Also provided are means communicating with the interior of the concavity through the body of the disc, and comprising at least holes 28 and 30 which define a pair of continuous passageways extending from the interior of the concavity 26 through the disc. Holes 28, 30 may but need not be identical. While neither their size nor configuration is particularly critical to the invention it is preferred that the holes be slightly conically flared outwardly from concavity 26 so as to provide a mating fit to means for injecting electrolyte paste therein. The disc is also provided with electrical connecting means comprising, in the form shown, one or more holes or sockets 32 which may be disposed about the edge of the disc, as shown in FIGS. 1 and 2. Each socket is adapted to be releasably engageable with a plug-in terminal 34, described hereinafter.

The surface of disc 22 is provided with provide thin, continuous coating 36 (FIG. 2) of an electrically conductive material. This coating provided at least a continuous electrical path between the interior of concavity 26 and the interior of the sockets 32. The coating may but need not totally enclose the disc, although for purposes of mass production, such a totally enclosing skin may be desirable. In the preferred embodiment, the coating is silver chloride which may be deposited or formed by any well known technique. Preferably, the disc is first coated with a thin (e.g. 40-50p.) layer of metallic silver applied, for example, by vacuum deposition or plating. The silver coated disc is then treated, for example, with a 1N solution of hydrochloric acid, to oxidize at least a surface layer of the silver to silver chloride. Silver chloride is particularly desirable for its mechanical qualities of toughness and excellent adhesion, and for its excellent and well known electrical conductivity. Further, it provides stable contact potentials when in contact with silver and with a chloride electrolyte such as NaCl.

Also shown in FIGS. 1 and 2 is contact sheet 24 which is formed of a thin flexible, electrically insulating material such as polypropylene, polyethylene or preferably polyethylene terephthalate, or the like. Hole 40 which preferably is substantially the same sizeand contour (but maybe smaller) as the surface periphery of concavity 26, is formed substantially at the center of sheet 24. Hole 40 should be centered on or registered with the periphery of concavity 26 so that hole 40 is adjacent the concavity and at least a portion of the concavity remains uncovered, while the remainder of sheet 24 wholly covers the surface of disc 22 around the concavity. Means for securing the sheet to the disc may comprise a known pressuresensitive adhesive 42. The other surface of sheet 24 is coated with a similar adhesive layer 44 so that it may be attached to the skin of a patient in such a manner that the concavity is disposed adjacent the skin. The adhesive preferably is of a nonallergenic type which will minimize or prevent lesions or other irritations to the skin. It should be noted that the pressure-sensitive adhesive may be protected by a release sheet 46, such as wax paper, which can be stripped off just prior to use. A group of electrodes can thus be stored loosely in a container without adhering to one another or can be enclosed in individual sterile packages. The disc and contact sheet portions may also be stored in separate containers if desired, with each portion being protected from one another by the use of similar release sheets.

Shaped to form a tight plug in fit in at least one of the sockets 32 is at least one terminal 34, one end of which is connected to the biopotential measuring instrument (not shown). The terminal 34 includes a current-carrying cross-sectional as a wire 48, which terminates in a plug in tip 50. Wire 48 may be of copper, aluminum or other commonly used electrically conductive metal or alloy. Tip 50 is preferably coated with metallic silver, or may comprise a section of pure silver connected to the end of wire 48. Tip 50 is dimensioned so that when it is inserted into a corresponding socket 32, the tip fits very snugly by distorting or stretching the socket, and only the silver of the tip contacts the silver chloride coating 36 so as to form thereby a silver/silver chloride junction. Accordingly, a

' An electrolytic paste or gel, such as that conventionally used with electrocardiograph instruments, and preferably comprising sodium chloride in agar or the like, is introduced through one of holes 28 or 30 into the concavity 26. An electrical potential can be measured and recorded by the measuring instrument when the paste is disposed so as to form a continuous path communicating with the skin and the silver chloride coat on the interior of the concavity, and when the plug in terminal is inserted into appropriate socket 32.

Advantages of the above described electrode are several. Because it is formed of a regularly shaped and relatively simple following of disc, it lends itself to mass production as by stamping or injection molding. The size of the electrode can vary widely, as desired. Should a small electrode be desired, the socket can be formed as a slotted opening 54 between two ridges formed integrally on the top of the disc, generally opposite concavity 26, as shown in FIG. 3. it should also be appreciated that the disc can be used without contact sheet 24, by affixing the pressure-sensitive adhesive to the disc itself, on the surface portion of. the latter about the periphery of the concavity, provided however thatthis adhesive will also serve to insulate the surface AgCl from the skin. Since the electrolyte is inserted through one of holes 28 or 30, the other hole or holes serves as a pressure relief vent during the operation of filling the concavity. Should the electrolyte dry out during prolonged operation, additional amounts can be readily inserted through one of holes 28 or 30. Moreover, the disc being of readily deformable material, it lends itself to the formation of integral connectors.

Since certain changes may be made in the above apparatus without departing from the scope of the invention herein involved it is intended that all matter contained in the above description or shown in the accompanying drawing shall be interpreted in an illustrative and not a limiting sense. For example, while the electrical connector integral with the disc has been described as being a female connector, it will be apparent that a protruding male connector appropriately coated can also be provided integral with the disc. In such case, tip 50 would then be a corresponding female coupling.

What I claim is:

1. For use with ,a conventional biopotential measuring instrument having at least one terminal connector attached thereto, and an electrolyte, an electrode for detecting skin potentials and comprising:

a member of electrically insulating material, said member having a first surface including at least one concavity for containing said electrolyte, at least two continuous passageways extending from said concavity to another surface of said member, and at least one connecting means integral with said member and sized to be releasably engageable with said terminal connector, said member having a surface coating of a thickness in the micron range and consisting of electrically conductive material, said coating having an oxidized surface layer of a substantially conductive salt of said conductive material, said coating providing a continuous electrical path from the interior of said concavity to and including, at least the portion of the surface of said connecting means which contacts said terminal connector.

2. An electrode as defined in claim 1 wherein said coating substantially totally encloses said member.

3. An electrode as defined in claim 1 wherein said coating comprises silver chloride.

4. An electrode as defined in claim 1 wherein said coating comprises a film of silver having a thin surface layer of silver chloride.

5. An electrode as defined in claim 1 wherein said connecting means shown of a mechanically deformable material and is sized so as to deform when engaged with said connector whereby to insure a tight fit.

6. An electrode as defined in claim 1 wherein said connecting means is a female-type ofcoupling.

7. An electrode as defined in claim 6 wherein said connecting means is a hole in said member.

8. An electrode as defined in claim 6 wherein said connecting means is a slotted opening in said member.

9. An electrode as defined in claim 1 including means for releasably securing said member to a skin surface with said concavity adjacent said skin surface and said another surface directed substantially away from said skin surface so that said electrolyte can be inserted through at least one of said passageways into said at least one concavity to form a continuous electrical path between said skin surface and the interior of said concavity, said means for releasably securing includes means for providing electrical insulation between said skin surface and the portion of said first surface disposed about the periphery of said concavity.

10. An electrode as defined in claim 9 wherein said means for releasably securing comprises a substantially flat sheet of electrically insulating material having a hole therein, one surface of said sheet being secured to the portion of said first surface disposed about said concavity so that said concavity is at least partially exposed through said hole.

11. An electrode as defined in claim 6 wherein said coating is provided on the inner surface of said female'type coupling connecting means.

Claims (10)

  1. 2. An electrode as defined in claim 1 wherein said coating substantially totally encloses said member.
  2. 3. An electrode as defined in claim 1 wherein said coating comprises silver chloride.
  3. 4. An electrode as defined in claim 1 wherein said coating comprises a film of silver having a thin surface layer of silver chloride.
  4. 5. An electrode as defined in claim 1 wherein said connecting means shown of a mechanically deformable material and is sized so as to deform when engaged with said connector whereby to insure a tight fit.
  5. 6. An electrode as defined in claim 1 wherein said connecting means is a female-type of coupling.
  6. 7. An electrode as defined in claim 6 wherein said connecting means is a hole in said member.
  7. 8. An electrode as defined in claim 6 wherein said connecting means is a slotted opening in said member.
  8. 9. An electrode as defined in claim 1 including means for releasably securing said member to a skin surface with said concavity adjacent said skin surface and said another surface directed substantially away from said skin surface so that said electrolyte can be inserted through at least one of said passageways into said at least one concavity to form a continuous electrical path between said skin surface and the interior of said concavity, said means for releasably securing includes means for providing electrical insulation between said skin surface and the portion of said first surface disposed about the periphery of said concavity.
  9. 10. An electrode as defined in claim 9 wherein said means for releasably securing comprises a substantially flat sheet of electrically insulating material having a hole therein, one surface of said sheet being secured to the portion of said first surface disposed about said concavity so that said concavity is at least partially exposed through said hole.
  10. 11. An electrode as defined in claim 6 wherein said coating is provided on the inner surface of said female-type coupling connecting means.
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Cited By (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845757A (en) * 1972-07-12 1974-11-05 Minnesota Mining & Mfg Biomedical monitoring electrode
US3882853A (en) * 1973-02-15 1975-05-13 Cardiodynamics Biomedical electrode
US3976055A (en) * 1973-12-17 1976-08-24 Ndm Corporation Electrode and conductor therefor
US4051842A (en) * 1975-09-15 1977-10-04 International Medical Corporation Electrode and interfacing pad for electrical physiological systems
US4067321A (en) * 1976-06-29 1978-01-10 Governor Of Tokyo Metropolis Electrodes for electroencephalographic examinations
US4094309A (en) * 1977-03-07 1978-06-13 Grzenia Robert M Medical electrode
US4126126A (en) * 1976-07-27 1978-11-21 C. R. Bard, Inc. Non-metallic pregelled electrode
FR2397825A1 (en) * 1977-07-18 1979-02-16 Mills Harold ECG electrode fitting equipment - has electrodes on elastic strip stretched to fit different patients
US4202344A (en) * 1976-10-05 1980-05-13 Harold Mills Electrocardiograph electrodes and associated assemblies
US4332257A (en) * 1980-02-11 1982-06-01 Bunker Ramo Corporation Medical clip and electrode constructions
US4393584A (en) * 1979-12-06 1983-07-19 C. R. Bard, Inc. Method of manufacture of electrode construction
US4458696A (en) * 1979-08-07 1984-07-10 Minnesota Mining And Manufacturing Company T.E.N.S. Electrode
US4522211A (en) * 1979-12-06 1985-06-11 C. R. Bard, Inc. Medical electrode construction
US4685467A (en) * 1985-07-10 1987-08-11 American Hospital Supply Corporation X-ray transparent medical electrodes and lead wires and assemblies thereof
US4700710A (en) * 1985-03-12 1987-10-20 Murray Electronics Associates Limited Partnership Apertured adhesively applied body electrode apparatus and method
US4776350A (en) * 1986-01-07 1988-10-11 Physio-Control Corporation External electrode for heart stimulation and connector therefor
WO1989002246A1 (en) * 1987-09-15 1989-03-23 Capintec, Inc. Ambulatory physiological evaluation system including cardiac monitoring
US4830014A (en) * 1983-05-11 1989-05-16 Nellcor Incorporated Sensor having cutaneous conformance
US4832036A (en) * 1985-05-13 1989-05-23 Baxter International Inc. Medical electrode
US4938218A (en) * 1983-08-30 1990-07-03 Nellcor Incorporated Perinatal pulse oximetry sensor
US5109849A (en) * 1983-08-30 1992-05-05 Nellcor, Inc. Perinatal pulse oximetry sensor
US5150708A (en) * 1990-12-03 1992-09-29 Spacelabs, Inc. Tabbed defibrillator electrode pad
US5217012A (en) * 1991-08-22 1993-06-08 Sensor Devices Inc. Noninvasive oximeter probe
US5228440A (en) * 1990-08-22 1993-07-20 Nellcor, Inc. Fetal pulse oximetry apparatus and method of use
US5261402A (en) * 1992-07-20 1993-11-16 Graphic Controls Corporation Snapless, tabless, disposable medical electrode with low profile
US5368025A (en) * 1991-08-22 1994-11-29 Sensor Devices, Inc. Non-invasive oximeter probe
US5551424A (en) * 1990-05-29 1996-09-03 Phox Medical Optics, Inc. Fetal probe apparatus
US5817008A (en) * 1996-10-31 1998-10-06 Spacelabs Medical, Inc. Conformal pulse oximetry sensor and monitor
USRE36000E (en) * 1990-10-19 1998-12-22 Nellcor Puritan Bennett Incorporated Adhesive pulse oximeter sensor with reusable portion
US5891021A (en) * 1998-06-03 1999-04-06 Perdue Holdings, Inc. Partially rigid-partially flexible electro-optical sensor for fingertip transillumination
US6622034B1 (en) 1999-09-10 2003-09-16 Imagenix, Inc. Oximeter sensor with functional liner
US6952605B1 (en) * 2000-08-10 2005-10-04 Respironics, Inc. Pneumatic release mechanism for a patient contacting article
US20080076989A1 (en) * 2006-09-21 2008-03-27 Starr Life Sciences Corp. Tail Mounting Clip for Securely Mounting Sensor to Tail and a Tail Mounted Pulse Oximetry Sensor System Using Same
US20080167564A1 (en) * 2007-01-10 2008-07-10 Starr Life Sciences Corp. Techniques for accurately deriving physiologic parameters of a subject from photoplethysmographic measurements
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
US20080194932A1 (en) * 2006-09-21 2008-08-14 Starr Life Sciences Corp. Small Animal Pulse Oximeter User Interface
US20080262326A1 (en) * 2007-04-19 2008-10-23 Starr Life Sciences Corp. Signal Processing Method and Apparatus for Processing a Physiologic Signal such as a Photoplethysmography Signal
US20090099425A1 (en) * 2007-10-10 2009-04-16 Starr Life Sciences Corp. Integrated tail mounted blood pressure monitor and pulse oximeter system for animal research
US20090223460A1 (en) * 2008-03-10 2009-09-10 Starr Life Sciences Corp. Bioactive gas supply chamber for animal research such as hypoxia studies on non-anesthetized small animals with direct physiologic monitoring
US20100075537A1 (en) * 2008-09-23 2010-03-25 Mcintire James F Connector for terminating a ribbon cable
US20100075549A1 (en) * 2008-09-23 2010-03-25 Mcintire James Francis Termination cap for terminating an electrical lead to a stud of an electrode and an electrode lead assembly containing such termination cap
US20100075527A1 (en) * 2008-09-23 2010-03-25 Mcintire James F Connector assembly for connecting an electrical lead to an electrode
US8005624B1 (en) 2004-04-26 2011-08-23 Starr Life Sciences Corp. Medical devices and techniques for rodent and small mammalian based research
US20120097545A1 (en) * 2010-05-20 2012-04-26 Toru Imori Silver electroplated and/or silver alloy electroplated article having an oxidation layer on its surface
WO2014107446A1 (en) * 2013-01-04 2014-07-10 The Regents Of The University Of California Eeg data collection intrabuccal method and apparatus
US10039466B2 (en) 2015-01-28 2018-08-07 City University Of Hong Kong Apparatus for detection of electrical signals of a biological subject and electrode thereof, and method of manufacture thereof

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Cited By (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845757A (en) * 1972-07-12 1974-11-05 Minnesota Mining & Mfg Biomedical monitoring electrode
US3882853A (en) * 1973-02-15 1975-05-13 Cardiodynamics Biomedical electrode
US3976055A (en) * 1973-12-17 1976-08-24 Ndm Corporation Electrode and conductor therefor
US4051842A (en) * 1975-09-15 1977-10-04 International Medical Corporation Electrode and interfacing pad for electrical physiological systems
US4067321A (en) * 1976-06-29 1978-01-10 Governor Of Tokyo Metropolis Electrodes for electroencephalographic examinations
US4126126A (en) * 1976-07-27 1978-11-21 C. R. Bard, Inc. Non-metallic pregelled electrode
US4202344A (en) * 1976-10-05 1980-05-13 Harold Mills Electrocardiograph electrodes and associated assemblies
US4094309A (en) * 1977-03-07 1978-06-13 Grzenia Robert M Medical electrode
FR2397825A1 (en) * 1977-07-18 1979-02-16 Mills Harold ECG electrode fitting equipment - has electrodes on elastic strip stretched to fit different patients
US4458696A (en) * 1979-08-07 1984-07-10 Minnesota Mining And Manufacturing Company T.E.N.S. Electrode
US4522211A (en) * 1979-12-06 1985-06-11 C. R. Bard, Inc. Medical electrode construction
US4393584A (en) * 1979-12-06 1983-07-19 C. R. Bard, Inc. Method of manufacture of electrode construction
US4332257A (en) * 1980-02-11 1982-06-01 Bunker Ramo Corporation Medical clip and electrode constructions
US4830014A (en) * 1983-05-11 1989-05-16 Nellcor Incorporated Sensor having cutaneous conformance
US4938218A (en) * 1983-08-30 1990-07-03 Nellcor Incorporated Perinatal pulse oximetry sensor
US5109849A (en) * 1983-08-30 1992-05-05 Nellcor, Inc. Perinatal pulse oximetry sensor
US4700710A (en) * 1985-03-12 1987-10-20 Murray Electronics Associates Limited Partnership Apertured adhesively applied body electrode apparatus and method
US4832036A (en) * 1985-05-13 1989-05-23 Baxter International Inc. Medical electrode
US4685467A (en) * 1985-07-10 1987-08-11 American Hospital Supply Corporation X-ray transparent medical electrodes and lead wires and assemblies thereof
US4776350A (en) * 1986-01-07 1988-10-11 Physio-Control Corporation External electrode for heart stimulation and connector therefor
WO1989002246A1 (en) * 1987-09-15 1989-03-23 Capintec, Inc. Ambulatory physiological evaluation system including cardiac monitoring
US5551424A (en) * 1990-05-29 1996-09-03 Phox Medical Optics, Inc. Fetal probe apparatus
US5743260A (en) * 1990-08-22 1998-04-28 Nellcor Puritan Bennett Incorporated Fetal pulse oximetry apparatus and method of use
US5228440A (en) * 1990-08-22 1993-07-20 Nellcor, Inc. Fetal pulse oximetry apparatus and method of use
US6370409B1 (en) 1990-08-22 2002-04-09 Nellcor Puritan Bennett, Inc. Positioning method for pulse oximetry fetal sensor
US6671530B2 (en) 1990-08-22 2003-12-30 Nellcor Puritan Bennett Incorporated Positioning method for pulse oximetry fetal sensor
USRE36000E (en) * 1990-10-19 1998-12-22 Nellcor Puritan Bennett Incorporated Adhesive pulse oximeter sensor with reusable portion
US5150708A (en) * 1990-12-03 1992-09-29 Spacelabs, Inc. Tabbed defibrillator electrode pad
US5217012A (en) * 1991-08-22 1993-06-08 Sensor Devices Inc. Noninvasive oximeter probe
US5368025A (en) * 1991-08-22 1994-11-29 Sensor Devices, Inc. Non-invasive oximeter probe
US5261402A (en) * 1992-07-20 1993-11-16 Graphic Controls Corporation Snapless, tabless, disposable medical electrode with low profile
US5817008A (en) * 1996-10-31 1998-10-06 Spacelabs Medical, Inc. Conformal pulse oximetry sensor and monitor
US5891021A (en) * 1998-06-03 1999-04-06 Perdue Holdings, Inc. Partially rigid-partially flexible electro-optical sensor for fingertip transillumination
US6622034B1 (en) 1999-09-10 2003-09-16 Imagenix, Inc. Oximeter sensor with functional liner
US6952605B1 (en) * 2000-08-10 2005-10-04 Respironics, Inc. Pneumatic release mechanism for a patient contacting article
US8005624B1 (en) 2004-04-26 2011-08-23 Starr Life Sciences Corp. Medical devices and techniques for rodent and small mammalian based research
US20080076989A1 (en) * 2006-09-21 2008-03-27 Starr Life Sciences Corp. Tail Mounting Clip for Securely Mounting Sensor to Tail and a Tail Mounted Pulse Oximetry Sensor System Using Same
US20080194932A1 (en) * 2006-09-21 2008-08-14 Starr Life Sciences Corp. Small Animal Pulse Oximeter User Interface
US8298154B2 (en) 2007-01-10 2012-10-30 Starr Life Sciences Corporation Techniques for accurately deriving physiologic parameters of a subject from photoplethysmographic measurements
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