US3409213A - Rotary seal and centrifuge incorporation - Google Patents

Rotary seal and centrifuge incorporation Download PDF

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US3409213A
US3409213A US61107367A US3409213A US 3409213 A US3409213 A US 3409213A US 61107367 A US61107367 A US 61107367A US 3409213 A US3409213 A US 3409213A
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seal
member
section
centrifuge
surface
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Jr Allen Latham
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500 Inc
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500 Inc
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16JPISTONS; CYLINDERS; SEALINGS
    • F16J15/00Sealings
    • F16J15/16Sealings between relatively-moving surfaces
    • F16J15/34Sealings between relatively-moving surfaces with slip-ring pressed against a more or less radial face on one member
    • F16J15/36Sealings between relatively-moving surfaces with slip-ring pressed against a more or less radial face on one member connected by a diaphragm or bellow to the other member
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S277/00Seal for a joint or juncture
    • Y10S277/907Passageway in rod or shaft

Description

Nov. 5, 1968 A. LATHAM, JR

ROTARY SEAL AND CENTRIFUGE INCORPORATION 2 Sheets-Sheet 2 Flled Jan. 23, 1967 INVENTOR.

r J m U h T O L n m A Attorney United States Patent 3,409,213 .ROTARY SEAL AND CENTRIFUGE INCORPORATION Allen Latliam, In, Jamaica Plain, Mass., assignor, by mesne assignments, to 500 Incorporated, Cambridge,

' Mass., acorporation of Delaware Filed Jan. 23, 1967, Ser. No. 611,073

' 14 Claims. (Cl. 233-21) ABSTRACT OF THE DISCLOSURE A rotary seal formed of a first rigid, low-friction member which Contacts a moving rigid member with minimal friction to make the dynamic seal, and a second elastomeric member which provides a resilient static seal and a spring action force between the surfaces of the dynamic seal. The seal is particularly suitable for centrifuges for continuous sterile operations such as the treating of blood.

In the process of storing or handling human blood it is necessary to carry out certain steps, among which is centrifuging. Apparatus has been developed to meet the particularly stringent demands which accompany handling of blood to prevent it from suffering traumatic effects. Among such apparatus are the specially designed centrifuges described in my United States Patent 3,145,713 and in a co-pending application of Richard F Cole Ser. No. 442,765, now Patent No. 3,317,127, assigned to the same assignee as the present invention. Although the rotary seal of this invention is particularly well adapted for use in the centrifuges described in the aforementioned patent and patent application, it has broad applications to pumps, centrifuges, and to stirring and mixing devices used in processing temperature-sensitive materials.

In a centrifuge for sterile processing it is necessary to provide an effective seal between the rotating and stationary members of the apparatus. In centrifuges suitable for continuously handling blood or other fluids subject to contamination it is desirable that the centrifuge bowl and its associated parts perform the rotation while the conduits which make up the fluid inlet and outlet of the centrifuge remain stationary. This then requires an effective rotating seal in which frictional heating is so low and the dissipation of heat toheat sinks is so high that the blood, or other heat-sensitive fluid, will not be exposed to any hot spots. Further, it requires a seal which does not produce any particulate contaminants which might be introduced into the blood or other liquid during its passage through the centrifuge. It is also desirable that such apparatus have seals which are simple to install and maintain in a clean, sterile condition. An additional requirement for the seal is that it achieves very high reliability in service. This in turn requires that the seal is capable of tolerating moderate misalignment and vibration between the rotating and nonrotating parts.

It is therefore a primary object of this invention to provide an improved rotary seal particularly well suited for use in centrifuges. It is another object of this invention to provide a rotary seal of the character described which does not develop localized heating and which does not'produce particulate contaminants. It is another object of this invention to provide such a rotary seal which is simple to construct, install, and maintain. It is still a further object to provide a seal which will operate with complete reliability despite moderate misalignment and vibration of the rotating and nonrotating parts. Other objects of the invention will in part be obvious and in part be apparent hereinafter.

The invention accordingly comprises the features of construction, combination of elements, and arrangement 3,409,213 Patented Nov, 5, 1968 of parts which will be exemplified in the construction hereinafter set forth and the scope of the invention will be indicated in the claims.

A number of different types of rotary seals have been used in the prior art. These generally include one or more O-ring secondary seals in addition to a carbon ring'and a metallic mating ring. In many cases they require as many as six different component parts and their rubbing surfaces, where the dynamic seal is effected, tend to overheat.

Summary of the invention The rotary seal of this invention is formed of only two members. The upper member is an elastomeric member which forms, through an upper contoured section, a static seal with a rotating member of the centrifuge which has a complementary configuration. The lower member of the rotary seal may be a carbon or graphite member which is contoured to fit the upper member and which has a lower surface which forms a low friction dynamic seal with a stationary member of the centrifuge. The surface of the stationary member which contacts the lower member of the rotary seal may be hard surfaced aluminum. Such a rubbing contact does not generate particulate contaminants. The aluminum, being a good heat conductor, rapidly dissipates and conducts away any localized heating generated by the dynamic seal. If the seal is to be reused, it is preferred that the two members are keyed to make it easy to snap them together and to separate them for sterilizing.

For a fuller understanding of the nature and objects of the invention, reference should be had to the following detailed description taken in connection with the accompanying drawings in which:

FIG. 1 is a cross section of a centrifuge incorporating one embodiment of the rotary seal of this invention;

FIG. 2 is a side elevational view of the upper member of the rotary seal of FIG. 1 removed from the sealing assembly of the centrifuge;

FIG. 3 is a cross section through the rotary seal of FIG. 1 taken along line 3-3 of that figure;

FIGS. 4 and 5 are cross sections of two additional embodiments of the rotary seal;

FIG. 6 is a partial cross section through the upper part of the centrifuge of FIG. 1 taken along line 66 of that figure and drawn to a smaller scale; and

FIG. 7 is a cross section through the lower part of the centrifuge of FIG. 1 taken along line 7-7 of that figure and drawn to a smaller scale.

The rotary sealing assembly of this invention is shown in detail in FIG. 1 as it may be installed in a centrifuge suitable for processing blood. Reference should also be had to various cross-sectional drawings where indicated. The main centrifuge body 10 terminates in its lower end in a flange 11. Internally it defines a cavity, and it can be considered to be formed of a number of different sectional configurations. Reading from top to bottom in FIG. 1 these are a keyed section 14, a first small cylindrical section 15, an inclined section 16, a second cylindrical section 17, a second inclined section 18, and finally a main cylindrical section 19 which, as will become apparent later, contains the major portion of the centrifuge core. The core can be seen to be made up of a central cylindrical section 24, having a conical or inclined upper section 25 and a core flange 26. This flange is adapted for engagement with a driving chuck in the well-known manner of centrifuge design and construction. This is done by aflixing the body and core through their respective flanges 11 and 26, sealed with an O-ring 28, by means of flange screws 30 and nuts 31 and using the larger flange to grip a chuck (not shown).

A core passage 38 runs axially through the center of the core 24 an da plurality of inclined radial passages 39 are drilled from the outside of the lower end of the cylindrical section of the core into the core passage.

The seal assembly rotates with the bowl and core, while other components of the centrifuge remain stationary as will be now described. Feed tube 44 is connected by any suitable means not shown to the source of liquid to be centrifuged. In its upper section this has a threaded section 45 which then gives way to a thicker walled section 46 and subsequently to a thinner walled section 47 which is within core passage 38 and axially aligned therein. The feed tube thereby defines a fluid passage 48 which offers direct communication between the fluid source and the volume within the centrifuge defined at the confluence 49 of the axial core passage 38 and the inclined radial passages 39 of the core.

A header 52, having a supernatant outlet conduit 53 is slipped down over section 46 of the feeder tube to rest on a shoulder 55 of an effluent tube 56. This external assembly is held in place by means of a threaded knurled nut 57 and sealing is accomplished through the use of O- ring seals 58 and 59. The eflluent tube 56 terminates at its lower end in a horizontal section 61 which, in turn is integral with a frusto conical section 62. The horizontal section 61 provides a shoulder 63 for supporting the sealing assembly. Directly below the horizontal and inclined sections of the effluent tube is positioned a passage-defining member aflixed to the enlarged section 46 of the feeder tube and consisting of a horizontal section 65 and an inclined section 66, the latter having a row of protuberances 67 (see FIG. 6) which act as spacer means between the two passage-defining members. These are ground on top so that they are on the same conical surface and at an angle corresponding to the conical angle of the contacting surface of section 62.

The rotary sealing assembly is generally indicated by the numeral 69 and it forms a fluid-tight seal between the rotating centrifuge body and the stationary members made up of the feed tube and the eflluent tube. Since the rotary seal rotates with bowlv 10 it must form a static seal at 70 and a dynamic seal at 71. It accomplishes this by forming a friction grip at its upper section with the centrifuge body and by making rubbing contact at the point of the dynamic seal 71.

The seal assembly is formed of an upper elastomeric member 73 and a lower rigid, low-friction member 74. The upper elastomeric member 73 can be considered to have three sections: namely, an upper keyed section 75, a lower keyed section 76, and thin deformable central section 77. The elastomeric member is molded in the configuration shown in FIG. 2. It is preferably molded of a material having an intermediate degree of hardness, e.g., from about 25 to 55 on the durometer scale. It will be seen that when this member is installed in the seal assembly (FIG. 1) the central deformable section is compressed; and .in this compressed state the upper and lower keyed sections are forced against their corresponding contacting surfaces. If the elastomeric member is formed of an excessively hard material it will be difiicult to mold and insert; while if it is too soft it will not hold its shape.

If the centrifuge orother device in which the seal is installed is used .to process liquid which must be maintained free from contamination, then the elastomeric sealing membenmust be formed of a material which can tolerate autoclaving or similar sterilizing. It must also be of a material with which such liquids may come in contact without experiencing any reaction therewith. In the case of centrifuges for processing blood the silicone rubbers have been found to be particularly well suited.

The lower rigid, low-friction seal member 74 has an upper keyed section 80 which is adapted to engage and snap into the lower keyed section 76 of elastomeric member 73. The central section 81 of the rigid, low-friction seal member is seen to have a spherical radius and its lower section 82 is in the form of a cylindrical collar, the

bottom surface of which makes rubbing contact with shoulder 63. This rigid, low-friction seal member is typically formed from carbon or graphite. However, it may also be formed of a molded polytetrafluoroethylene which is desirably loaded (at least on its surface) with a material such as graphite or other rigid, wear-resistant substance. The effluent tube 56 is preferably formed of aluminum and its shoulder 63 which makes rubbing contact with sealing member 74 is given a treatment to harden it. Typically, this consists of forming a relatively thick oxide coating on it to give it, in effect, a sapphire surface which is harder than the surface of sealing member 74. The rubbing contact surfaces should be accurately lapped. The resulting dynamic seal at 71 is one which is low in friction, very resistant to wear and does not generate any particulate contaminant matter. Heat generated at the dynamic seal is conducted by efiluent tube 56 to tube gripping means (not shown) for dissipation into the atmosphere.

The spherical radius of the central section of sealing member 74 permits the sealing assembly to tolerate moderate misalignment and also prevents any possible damage which might be done to themember during its installation in the centrifuge. The rotary seal assembly is so designed as to be maintained in its proper position at all times while permitting gross clearances between the two members and the outside wall of the eflluent tube 56. The clearance 84 between the upper member and tube 56 may be inch or even more; while the clearance 84a between the lower member (which is less than clearance 84) may be up to about inch. Such relatively large clearances are possible because of the design and configuration of the seal assembly and because of the configuration of the housing around it, particularly to the lip 83 which prevents the upper part of the elastomeric member 73 from extruding upward and around the outer surface of the eflluent tube 56. The gross clearances which are possible permit the apparatus to tolerate some misalignment of the rotating and non-rotating components without causing wear through bearing contact; and the protuberances 67 used as spacers between 62 and 66 prevent any distortion of the sealing assembly at the surface of the dynamic seal 71.

Modifications may be made in the configurations of the two members making up the rotary seal. Two of these modifications are illustrated in FIGS. 4 and 5. In FIG. 4 the barbs of the keyed sections are eliminated and replaced with straight-lined sections 85 and 86 in the clastomeric member and a corresponding section 87 in the rigid, low-friction member. This design is satisfactory for sealing members which are to be used only once and then thrown away. In such one-use seal assemblies the elastomeric and rigid, low-friction members may also be bonded along the lower contacting surfaces of sections 86 and 87 with a suitable adhesive, such as a silicone calking compound.

In the modification of FIG. 5 the bottom surface of the keyed section 76 of the elastomeric member is formed with several spaced tongues 88 and the mating surface of the rigid, low-friction member has corresponding grooves 89. This tongue-and-groove arrangement contributes to the locking of these two members. This type of locking is, of course, also applicable to the embodiment of FIG. 4.

The flow of the fluid into the centrifuge and the dis-v charge of the supernatant liquid from the centrifuge may best be explained by tracing the various passages through which the liquid enters and the effluent is discharged. The fluid to be centrifuged travels downwardly through sta-. tionary passage 48 and onto rotating surface 49 from which it passes by centrifugal force through radial passages 39 into annular passage 90 which will be seen to be defined between the internal wall of the centrifuge body section 19 of the bowl and the external wall of the cylindrical core section 24. The primary centrifugal processing occurs in space 90. The supernatant liquid passes up through narrow passage 91, which is defined between the inclined sections ofthe body and core, through passage 97 and then into passage 92 which is defined by the pas sage defining member 62 and 66. This, in turn, communicates with a horizontal passage 93 defined between sections 61 and 65 and finally enters theannular passage 94 which is defined between the enlarged section 46 of the'feed tube and the diluent tube 56. This passage 94 leads directly into discharge conduit 53. Regions 38, 96 and 98 remain filled with air, or other gases, which was present in the bowl at the start of the operation.

An examination of FIG. 1 will show that the seal affords complete protection for the fluid being treated. There is no way in which contaminants, including bacteria, dust, etc., can enter the centrifuge through the rotary seal; and there is no way in which any of the liquid can be removedexcept through the fluid passage provided. There is therefore provided a completely isolated processing volume and a sterile regime.

A centrifuge, constructed as shown in FIG. 2 has been used to centrifuge components of human blood to concentrate. platelets from platelet-rich plasma and wash the platelets to remove plasma. The rotary seal performed satisfactorily and the platelets thus prepared exhibited excellent morphological characteristics and other desirable attributes.

It is, of course, within the scope of this invention to use the rotary seal in a device wherein the seal, along with that portion of the apparatus with which it makes a static seal, remains stationary while the remaining portion of the device rotates. The seal may also, of course, be used in any equipment, other than centrifuges, where similar operational requirements exist.

It will thus be seen that the objects set forth above, among those made apparent from the preceding description, are efiiciently attained and, since certain changes may be made in the above construction without departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the accompanying drawing shall be interpreted as illustrative and not in a limiting sense.

It is also to be understood that the following claims are intended to cover all of the generic and specific features of the invention herein described, and all statements of the scope of the invention which, as a matter of language, might be said to fall therebetween.

I claim:

1. A sealing assembly capable of effecting a fluidtight seal between two components, one of which is rotatable relative to the other, comprising in combination:

(a) an elastomeric ring member capable of forming a static seal with one of said components and having upper and lower sections with friction-generating outer surfaces and a pressure-deformable central section; and

(b) a rigid, low-friction ring member capable of forming a dynamic seal and having an upper section adapted to form a friction grip with said lower section of said elastomeric member, a central section the outer surface of which is contoured and defined by a spherical radius, and a lower surface adapted to make a low-friction rubbing contact with a surface of the other of said components.

2. A sealing assembly in accordance with claim 1 wherein said elastomeric ring member is formed of a silicone rubber having a hardness between about 25 and 55 on the durometer scale.

3. A sealing assembly in accordance with claim 1 wherein said rigid, low-friction ring member is formed of graphite.

4. A sealing assembly in accordance with claim 1 wherein said rigid, low-friction ring member is formed of polytetrafiuoroethylene at least the rubbing surface of which is filled with a rigid, wear-resistant material.

5. A sealing assembly in accordance with claim 1 wherein said upper and lower sections of said elastomeric corporated therein a sealing assembly capable of effecting a fluid-tight seal between said rotating assembly and said stationary assembly, said sealing assembly comprising in combination (a) an elastomeric ring member capable of forming a static seal with said rotating component and having upper and lower sections with friction-generating outer surfaces and a pressure-deformable central section;fand V Y (b) a rigid, low-friction ring member capable of forming a dynamic seal and having an upper section adapted to form a friction grip with said lower sec tion of said elastomeric member, a central section the outer surface of which is contoured and defined by a spherical radius, and a lower surface adapted to make a low-friction rubbing cont-act with a surface of said stationary component.

8. A centrifuge in accordance with claim 7 wherein said stationary component is adapted to conduct any frictionally generated heat away from said surface where said rubbing contact is made thereby to prevent the heating of the fluid being centrifuged.

9. A centrifuge in accordance with claim 8 wherein at least that part of said stationary component which is adapted to conduct heat is formed of aluminum and said surface of said stationary component where said rubbing contact is made is oxidized to form a sapphire-like surface.

10. A centrifuge adapted to process liquids which must be maintained free from contaminants and from localized heating and having a first and second assembly of components one of which is capable of rotating relative to the other, comprising in combination (a) said first assembly of components comprising (1) feed tube means extending into said centrifuge and having attached to the wall thereof at a point intermediate between its two ends a horizontal ring which terminates in a first downwardly inclined skirt,

(2) efiluent tube means surrounding said feed tube means above said horizontal ring and defining therewith an annular channel adapted to provide supernatant liquid withdrawal means, said effluent tube means terminating at its lower end in a horizontally disposed shoulder member having a second downwardly inclined skirt, said shoulder member providing a dynamic sealing surface; said horizontal ring and first downwardly inclined skirt of said feed tube means being positioned below said collar member and said second downwardly inclined skirt of said effluent tube means and arranged in spaced relationship therewith to define a fiuid passage communicating between the centrifuge and said annular channel;

(b) said second assembly of components comprising (1) a centrifuge core having a centrally positioned passage into which said feed tube extends,

(2) a centrifuge housing surrounding said centrifuge core and defining around at least a portion of said efiluent tube means a recess adapted to hold a rotary seal assembly; and

(c) a rotary seal assembly disposed around said efilucut tube means and defining a spacing therewith, said seal assembly comprising (1) an elastomeric ring member capable of forming a static seal with a portion of the surface of said recess of said centrifuge housing said elastomeric ring member having upper and lower sections with friction-generating outer surfaces and a pressure-deformable central section; and (2) a rigid, low-friction ring member capable of forming a dynamic seal and having an upper section adapted to form a friction grip with said lower section of said elastomeric member, a central section the outer surface of which is contoured and defined by a spherical radius, and a lower surface adapted to make a lowfriction rubbing contact with said dynamic sealing surface of said shoulder of said efiiucnt tube means.

11. A centrifuge in accordance with claim 10 wherein said efiluent tube means is formed of a material having a high heat conductivity and said dynamic sealing surface of said shoulder member is treated to increase its hardness.

12. A centrifuge in accordance with claim 11 wherein said high heat conductivity material is aluminum and 2 said dynamic sealing surface is oxidized aluminum to provide a sapphire-like surface.

13. A centrifuge in accordance with claim 10 wherein said spacing between said elastomeric ring member of said seal assembly and said effiuent tube is at least inch and said spacing between said hard-surface ring member and said effluent tube is no greater than inch, whereby minor misalignments of said centrifuge components may be tolerated without developing bearing surfaces.

14. A centrifuge in accordance with claim 10 wherein second downwardly inclined skirt has a circle of spaced protuberances of the same height adapted to contact the lower surface of said first downwardly inclined skirt thereby to define said fluid passage and to prevent distortion of said sealing assembly at .said dynamic sealing surface. I I 1 References Cited 1 UNITED STATES PATENTS 2,610,075 9/1952 Haake ;277 90 3,027,165 3/1962 Kempff 277-j88'x 3,122,375 2/1964 Greenw'ald 277 ss 3,145,713 8/1964 Latham 233 22 x 3,117,127 5/1967 Cole 233 26 ROBERT W. JENKINS, Primary Examiner.

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Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565330A (en) * 1968-07-11 1971-02-23 Cryogenic Technology Inc Rotary seal and centrifuge incorporating same
US4300717A (en) * 1979-04-02 1981-11-17 Haemonetics Corporation Rotary centrifuge seal
US4629564A (en) * 1984-03-01 1986-12-16 Alfa-Laval Separation Ab Centrifugal separator with annular sealing means arranged around the rotor outlet for separated liquid
FR2588489A1 (en) * 1985-10-11 1987-04-17 Cardivascular Systems Centrifuge
US4684361A (en) * 1985-10-11 1987-08-04 Cardiovascular Systems, Inc. Centrifuge
US4692136A (en) * 1985-10-11 1987-09-08 Cardiovascular Systems Inc. Centrifuge
US4718888A (en) * 1986-03-10 1988-01-12 Cardiovascular Systems, Inc. Centrifuge bowl mount
US4767396A (en) * 1987-03-03 1988-08-30 Haemonetics Corporation Method and apparatus for processing biological fluids
US4795419A (en) * 1985-10-11 1989-01-03 Kardiothor, Inc. Centrifuge
US4859333A (en) * 1987-04-07 1989-08-22 Dideco S.P.A. Continous blood centrifugation cell
US4879031A (en) * 1987-04-07 1989-11-07 Dideco S.P.A. Blood centrifugation cell
US5045048A (en) * 1990-03-29 1991-09-03 Haemonetics Corporation Rotary centrifuge bowl and seal for blood processing
EP0471533A1 (en) * 1990-08-17 1992-02-19 SMITH & NEPHEW DYONICS INC Surgical device
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube
US5387174A (en) * 1993-01-29 1995-02-07 Elp Rochat Centrifugal separator with disposable bowl assembly
US5514070A (en) * 1994-01-21 1996-05-07 Haemonetics Corporation Plural collector centrifuge bowl for blood processing
US5584577A (en) * 1993-03-25 1996-12-17 Whirlpool Corporation Seal for a food blender
US5882289A (en) * 1996-04-03 1999-03-16 Haemonetics Corporation Centrifuge bowl with improved core structure
US5919125A (en) * 1997-07-11 1999-07-06 Cobe Laboratories, Inc. Centrifuge bowl for autologous blood salvage
US5976388A (en) * 1997-05-20 1999-11-02 Cobe Cardiovascular Operating Co., Inc. Method and apparatus for autologous blood salvage
US6352499B1 (en) * 1996-10-25 2002-03-05 Peter Geigle Process for operating a blood centrifugation unit
US6464624B2 (en) * 1999-06-03 2002-10-15 Haemonetics Corporation Blood processing method and apparatus using a centrifugation bowl with filter core
US6629919B2 (en) * 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
US20060199720A1 (en) * 2005-01-21 2006-09-07 Tien-Chu Juan Plasmapheresis centrifuge bowl
US20080124700A1 (en) * 2006-11-27 2008-05-29 Matteo Fortini Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl
US20080132397A1 (en) * 2005-01-25 2008-06-05 Jean-Denis Rochat Centrifugal Separator For a Physiological Fluid, Particularly Blood
US20080153686A1 (en) * 2005-01-25 2008-06-26 Jean-Denis Rochat Disposable Device for the Continuous Centrifugal Separation of a Physiological Fluid
US20090305863A1 (en) * 2008-06-10 2009-12-10 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US8454548B2 (en) 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US8628489B2 (en) 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US8647289B2 (en) 2008-04-14 2014-02-11 Haemonetics Corporation System and method for optimized apheresis draw and return
US8808978B2 (en) 2010-11-05 2014-08-19 Haemonetics Corporation System and method for automated platelet wash
US8834402B2 (en) 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US9308314B2 (en) 2011-04-08 2016-04-12 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2610075A (en) * 1950-01-13 1952-09-09 Crane Packing Co Rotary mechanical seal with telescoping parts
US3027165A (en) * 1959-08-13 1962-03-27 Federal Mogul Bower Bearings Steel insert die-cast face seal
US3117127A (en) * 1961-02-27 1964-01-07 Sterling Drug Inc 3-and 4-acetamidopiperidinium halides
US3122375A (en) * 1960-11-01 1964-02-25 Garrett Corp Dynamic fluid seal
US3145713A (en) * 1963-09-12 1964-08-25 Protein Foundation Inc Method and apparatus for processing blood

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2610075A (en) * 1950-01-13 1952-09-09 Crane Packing Co Rotary mechanical seal with telescoping parts
US3027165A (en) * 1959-08-13 1962-03-27 Federal Mogul Bower Bearings Steel insert die-cast face seal
US3122375A (en) * 1960-11-01 1964-02-25 Garrett Corp Dynamic fluid seal
US3117127A (en) * 1961-02-27 1964-01-07 Sterling Drug Inc 3-and 4-acetamidopiperidinium halides
US3145713A (en) * 1963-09-12 1964-08-25 Protein Foundation Inc Method and apparatus for processing blood

Cited By (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565330A (en) * 1968-07-11 1971-02-23 Cryogenic Technology Inc Rotary seal and centrifuge incorporating same
US4300717A (en) * 1979-04-02 1981-11-17 Haemonetics Corporation Rotary centrifuge seal
US4629564A (en) * 1984-03-01 1986-12-16 Alfa-Laval Separation Ab Centrifugal separator with annular sealing means arranged around the rotor outlet for separated liquid
FR2588489A1 (en) * 1985-10-11 1987-04-17 Cardivascular Systems Centrifuge
US4684361A (en) * 1985-10-11 1987-08-04 Cardiovascular Systems, Inc. Centrifuge
US4692136A (en) * 1985-10-11 1987-09-08 Cardiovascular Systems Inc. Centrifuge
US4795419A (en) * 1985-10-11 1989-01-03 Kardiothor, Inc. Centrifuge
US4718888A (en) * 1986-03-10 1988-01-12 Cardiovascular Systems, Inc. Centrifuge bowl mount
US4767396A (en) * 1987-03-03 1988-08-30 Haemonetics Corporation Method and apparatus for processing biological fluids
US4859333A (en) * 1987-04-07 1989-08-22 Dideco S.P.A. Continous blood centrifugation cell
US4879031A (en) * 1987-04-07 1989-11-07 Dideco S.P.A. Blood centrifugation cell
US5045048A (en) * 1990-03-29 1991-09-03 Haemonetics Corporation Rotary centrifuge bowl and seal for blood processing
US5133729A (en) * 1990-08-17 1992-07-28 Smith & Nephew Dyonics Inc. Motor driven hand piece for a surgical tool
EP0471533A1 (en) * 1990-08-17 1992-02-19 SMITH & NEPHEW DYONICS INC Surgical device
US5312319A (en) * 1992-04-29 1994-05-17 Cobe Laboratories, Inc. Centrifuge having a single swing arm for retaining a stator tube
US5387174A (en) * 1993-01-29 1995-02-07 Elp Rochat Centrifugal separator with disposable bowl assembly
US5584577A (en) * 1993-03-25 1996-12-17 Whirlpool Corporation Seal for a food blender
US5514070A (en) * 1994-01-21 1996-05-07 Haemonetics Corporation Plural collector centrifuge bowl for blood processing
US5882289A (en) * 1996-04-03 1999-03-16 Haemonetics Corporation Centrifuge bowl with improved core structure
US6352499B1 (en) * 1996-10-25 2002-03-05 Peter Geigle Process for operating a blood centrifugation unit
US5976388A (en) * 1997-05-20 1999-11-02 Cobe Cardiovascular Operating Co., Inc. Method and apparatus for autologous blood salvage
US5919125A (en) * 1997-07-11 1999-07-06 Cobe Laboratories, Inc. Centrifuge bowl for autologous blood salvage
US6464624B2 (en) * 1999-06-03 2002-10-15 Haemonetics Corporation Blood processing method and apparatus using a centrifugation bowl with filter core
US6629919B2 (en) * 1999-06-03 2003-10-07 Haemonetics Corporation Core for blood processing apparatus
US20060199720A1 (en) * 2005-01-21 2006-09-07 Tien-Chu Juan Plasmapheresis centrifuge bowl
US20080132397A1 (en) * 2005-01-25 2008-06-05 Jean-Denis Rochat Centrifugal Separator For a Physiological Fluid, Particularly Blood
US20080153686A1 (en) * 2005-01-25 2008-06-26 Jean-Denis Rochat Disposable Device for the Continuous Centrifugal Separation of a Physiological Fluid
US8070664B2 (en) * 2005-01-25 2011-12-06 Jean-Denis Rochat Disposable device for the continuous centrifugal separation of a physiological fluid
US8348823B2 (en) 2005-01-25 2013-01-08 Jean-Denis Rochat Disposable device for the continuous centrifugal separation of a physiological fluid
US20080124700A1 (en) * 2006-11-27 2008-05-29 Matteo Fortini Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl
US8506825B2 (en) 2006-11-27 2013-08-13 Sorin Group Italia S.R.L. Method and apparatus for controlling the flow rate of washing solution during the washing step in a blood centrifugation bowl
US9364600B2 (en) 2008-04-14 2016-06-14 Haemonetics Corporation System and method for optimized apheresis draw and return
US8808217B2 (en) 2008-04-14 2014-08-19 Haemonetics Corporation System and method for plasma reduced platelet collection
US8454548B2 (en) 2008-04-14 2013-06-04 Haemonetics Corporation System and method for plasma reduced platelet collection
US8702637B2 (en) 2008-04-14 2014-04-22 Haemonetics Corporation System and method for optimized apheresis draw and return
US9095665B2 (en) 2008-04-14 2015-08-04 Haemonetics Corporation Three-line apheresis system and method
US8647289B2 (en) 2008-04-14 2014-02-11 Haemonetics Corporation System and method for optimized apheresis draw and return
US8628489B2 (en) 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US8485957B2 (en) * 2008-06-10 2013-07-16 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US8262552B2 (en) * 2008-06-10 2012-09-11 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US20090305863A1 (en) * 2008-06-10 2009-12-10 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US7993257B2 (en) * 2008-06-10 2011-08-09 Sorin Group Italia S.R.L. Securing mechanism, particularly for blood separation centrifuges and the like
US9248227B2 (en) 2009-03-12 2016-02-02 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US8834402B2 (en) 2009-03-12 2014-09-16 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US9789243B2 (en) 2009-03-12 2017-10-17 Haemonetics Corporation System and method for the re-anticoagulation of platelet rich plasma
US8808978B2 (en) 2010-11-05 2014-08-19 Haemonetics Corporation System and method for automated platelet wash
US9833794B2 (en) 2010-11-05 2017-12-05 Haemonetics Corporation System and method for automated platelet wash
US9302042B2 (en) 2010-12-30 2016-04-05 Haemonetics Corporation System and method for collecting platelets and anticipating plasma return
US9308314B2 (en) 2011-04-08 2016-04-12 Sorin Group Italia S.R.L. Disposable device for centrifugal blood separation

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