US3370754A - Syringe for mixing and dispensing two ingredients - Google Patents

Syringe for mixing and dispensing two ingredients Download PDF

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Publication number
US3370754A
US3370754A US61369266A US3370754A US 3370754 A US3370754 A US 3370754A US 61369266 A US61369266 A US 61369266A US 3370754 A US3370754 A US 3370754A
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Prior art keywords
compartment
means
port
main
plunger
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Ralph J Cook
Joseph M Schumann
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Products Research and Chemical Corp
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Products Research and Chemical Corp
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/02Feed or discharge mechanisms
    • B01F15/0201Feed mechanisms
    • B01F15/0205Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartiments or cartridges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C5/00Filling or capping teeth
    • A61C5/60Devices specially adapted for pressing or mixing capping or filling materials, e.g. amalgam presses
    • A61C5/62Applicators, e.g. syringes or guns
    • A61C5/64Applicators, e.g. syringes or guns for multi-component compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C9/00Impression cups, i.e. impression trays; Impression methods
    • A61C9/0026Syringes or guns for injecting impression material; Mixing impression material for immediate use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/005Medical syringes, e.g. enemata; Irrigators comprising means for injection of two or more media, e.g. by mixing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F11/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F11/008Mixers with shaking, oscillating, or vibrating mechanisms the stirrers performing an oscillatory, vibratory or shaking movement
    • B01F11/0082Mixers with shaking, oscillating, or vibrating mechanisms the stirrers performing an oscillatory, vibratory or shaking movement performing a rectilinear reciprocating movement
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/0016Movable or transportable mixing devices or plants
    • B01F13/0018Movable mixing devices, i.e. apt to be shifted or displaced from one place to another, e.g. by human force
    • B01F13/002Movable mixing devices, i.e. apt to be shifted or displaced from one place to another, e.g. by human force portable during use, e.g. hand-held
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F13/00Other mixers; Mixing plant, including combinations of mixers, e.g. of dissimilar mixers
    • B01F13/0016Movable or transportable mixing devices or plants
    • B01F13/0018Movable mixing devices, i.e. apt to be shifted or displaced from one place to another, e.g. by human force
    • B01F13/002Movable mixing devices, i.e. apt to be shifted or displaced from one place to another, e.g. by human force portable during use, e.g. hand-held
    • B01F13/0023Of the syringe, cartridge type
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/02Feed or discharge mechanisms
    • B01F15/0201Feed mechanisms
    • B01F15/0205Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartiments or cartridges
    • B01F15/0213Opening valves which close-off openings between compartments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/02Feed or discharge mechanisms
    • B01F15/0201Feed mechanisms
    • B01F15/0205Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartiments or cartridges
    • B01F15/0215Removing separation walls, plugs which close off the different compartments, e.g. by rotation, axially sliding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/02Feed or discharge mechanisms
    • B01F15/0201Feed mechanisms
    • B01F15/0222Feed mechanisms characterized by the relative arrangement of the containers for feeding or mixing the components
    • B01F15/0223Feed mechanisms characterized by the relative arrangement of the containers for feeding or mixing the components the containers being connected coaxially before contacting the contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/00435Drives, e.g. for reciprocating motion; Transmissions; Brakes; Couplings
    • B01F15/00487Nature of the drive
    • B01F15/00506Hand driven

Description

Feb. 27, 1968 R. .1. cooK ET Al- 3,370,754

SYRINGE FOR MIXING AND DISPENSING TWO INGREDIENTS Filed Dec. 2l, 1966 3 Sheets-Sheet l Feb. 27, 1968 R. .1. COOK ET Al. 3,370,754

SYRINGE FOR MIXING AND DISPENSING TWO INGREDIENTS Filed Dec. 2l, 1966 3 Sheets-Sheet 2 Feb..27, 1968 R. J. COOK ET Al- 3,370754 SYRINGE FOR MIXING AND DISPENSING TWO INGREDIENTS 3 Sheets-Sheet Z5 Filed Dec. 2l, 1966 United States Patent O 3,370,754 SYRINGE FR MlXNG AND DSPENSING TW() INGREDIENTS Ralph J. Cook, Torrance, and Joseph M. Schumann, Inglewond, Calif., said Cook assignor to Products Research & Chemical Corporation, Burbank, Calif., a corporation of California Continuation-impart of application Ser. No. 464,978,

June 18, 1965. This application Dec. 21, 1966, Ser.

23 Claims. (Cl. 222-132) ABSTRACT F THE DISCLSURE In a dual compartment container comprising three telescoping hollow members, the outer member forms a main compartment with the dispensing port at one end and the two remaining members are slidable in the outer member to dispense the contents of the main compartment. The two remaining members cooperate to form a second compartment having an inner port for communication with the main compartment and said two remaining members are slidable relative to each other to contract the second compartment to expel its contents through the inner port into the main compartment. A rod means normally closes the dispensing port and is not only operable to open the inner port but is also operable to reciprocate a dasher in the main compartment.

This application is a continuation-impart of our application Serial No. 464,978 entitled Syringe for Mixing and Dispensing Two ingredients, filed lune 18, 1965 now abandoned.

This invention relates to a device for packaging two separate ingredients and additionally intermixing the two ingredients and dispensing the mixture.

While the invention is widely applicable for its basic purpose it has been initially embodied as a disposable plastic syringe for packaging a composition together with a separate catalyst that is capable of causing the composition to solidify quickly into an elastomeric mass. Such a dual compartment syringe may be used in the medical eld for molding soft resilient objects in body cavities. For example, the invention may be used to mold an elastomeric object inside a human ear for use in a hearing aid or may be used to duplicate the conguration of -an oral cavity for dental work. The disclosure herein of this initial embodiment of the invention will provide adequate guidance for those skilled in the art who may have occasion to apply the same principles for other specific purposes.

One requirement for such a disposable dual compartment mixing and dispensing syringe is that the construction be suitable for mass production at relatively low cost. Another requirement is that the device may be relied upon to confine the two ingredients etectively in complete isolation from each other for storage, shipment and shelf life prior to actual use. It is also requiste that the device be adapted for easy filling by the two ingredients.

A further requirement is that the device not only be eficient for its purpose of quickly interrnixing the two ingredients but also have a simple and more or less obvious mode of operation.

For diverse applications, it is essential that the device be capable of use interchangeably with various nozzles or needles of specialized configurations. Finally, the device should be versatile in the sense of being adaptable for packaging a wide range of accurately predetermined proportions of the two ingredients. The range should be suicient, for example, to include a ratio as high as 50:1,

ice

since a highly useful silicone composition requires a catalyst of a quantity that is equal to only 1/50 of the quantity of the base composition.

The present invention meets these requirements by providing a syringe shell to form a first or main compartment to contain the base ingredient and by providing a main plunger to expel the contents of the main compartment through a dispensing port, the main plunger being hollow to contain the second smaller ingredient. The second smaller compartment formed by the main plunger has an inner port in communication with the first compartment and a secondary plunger mounted in the main plunger is operable to transfer the second ingredient through the inner `port into the first compartment. Manually operable means normally closes both the inner port and the dispensing port and, iinally, a manually operable dasher is provided inside the shell to intermix the two ingredients in preparation for the dispensing operation.

It will be apparent to those skilled in the art that the manually operable means for closing the two ports and the manually operable dasher means may take various forms in various practices of the invention. In this regard a feature of the preferred embodiment of the invention is the concept of employing retractable means in the form of an operating rod for the multiple purposes of normally closing the dispensing port, normally closing the inner port and releasably engaging the dasher means for actuation thereof.

A further feature is lthe concept of providing the dispening port with an external tapered surface for engagement by a tapered socket of a separate nozzle or needle and of further providing the operating rod with a knob having atapered socket to engage the tapered surface to hold the operating rod in its normal position. Thus the knob which serves as a handle for reciprocating the dasher means not only encloses and protects the tapered external surface of the syringe until the time of use but also cooperates with the tapered surface to keep the two compartments of the syringe tightly closed until the time of use.

In some instances, a catalyst may deteriorate with the passage of time to shorten the shelf life of the filled container even though the catalyst is effectively isolated from the base material. -It has been found, however, that in some instances, the shelf life of such a catalyst may be extended indefinitely if at least one ingredient of the catalyst is kept isolated from the remainder of the catalyst. Accordingly in another practice of the invention, the telescoped assembly includes not only the main compartment formed by the shell and a second compartment formed by the main plunger but also a third compartment formed by the auxiliary plunger, the third compartment being closed by a third plunger.

With the base material in the main compartment and with at least one constituent of the catalyst in the second compartment and the remainder of the catalyst in the third compartment, the shelf life of the complete package is as long as vmay be desired. At the time of use, first the third plunger is advanced to combine the separated constituents of the catalyst and then the auxiliary plunger is advanced to inject the combined catalyst into the main compartment for mixing with the base ingredient.

The features and advantages of the invention may be understood from the following detailed description and the accompanying drawings.

In the drawings, which are to be regarded as merely illustrative FIG. 1 is a side elevation of the dual compartment syringe with the syringe serving as a container for the two separate ingredients;

FIG. 2 is a longitudinal sectional view on enlarged scale taken as indicated by the line 2-2 of FIG. l;

FIG. 2 showing the main plunger assembly in cross section;

FIG. 5 is a fragmentary perspective view showing the dasher with an operating rod releasably connected thereto;

FIG. 6 is a fragmentary sectional View similar to FIG. 2 showing the rst step in the operation of the device at the time of use, the rst step being to retract the operating rod suiciently to place the small compartment containing the minor ingredient in communication with the larger compartment containing the base ingredient;

FIG, 7 is a similar sectional view illustrating the second step in the l*operation `of the device which consists 0f employing the secondary plunger to displace the minor ingredient into the main compartment;

FIG. 8 is a si-milar view illustrating the third step of reciprocating the dasher to intermix the two ingredients and further illustrating the step of disengaging the operating rod from the dasher and withdrawing the operating rod from the dispensing port of the syringe;

FIG. 9 is -a similar View illustrating the final step of operating the main plunger to dispense the mixed ingredients through a suitable nozzle or needle;

FIG. 9a is afragmentary sectional View showing how a cap may be substituted for a knob on the end of the rod member in the first embodiment of the invention;

FIG. 10 is a sectional View similar to FIG. 2'illustrating the second embodiment of the invention wherein a three-compartment syringe serves as a container for three isolated ingredients;

FIG. 11 is a similar fragmentary sectional view illustrating the first step oftransferring an ingredient from the third compartment to the second compartment;

FIG. l2 is a similar fragmentary sectional view illustrating the transfer of the two intermixed ingredients from the second compartment to the third compartment; and

FIG. 13 is a fragmentary transverse cross-sectional View on a larger scale taken along the line 13-13 of'FIG. 11, the view showing radial grooves at the bottom of the second compartment to permit the material to liow past a ball member. The principal parts of the device include: a shell 10 forming a first or main compartment 11 for the rst larger ingredient, the shell being formed with a dispensing port 12; a main plunger, generally designated 14, slidingly mounted in the shell 10 for expelling the contents of the main compartment v11 through the dispensing port, the main plunger bein-g hollow to form a second smaller compartment 15 to contain the second ingredient, the smaller compartment having a restricted inner port 16 in communication with the main compartment 11; a secondary pllunger 18 slidingly mounted in the main plunger 14 for the purpose of forcing the second ingredient from the smaller compartment 15 into the main compartment; a

dasher 20 inside the main compartment for intenmixing the two ingredients; a small plug 22 that is unitary with the dasher 20 and normally seats in the inner port 16 to isolate the ingredient in the smaller compartment from the ingredient in the main compartment; a retractable member in the for-m of an operating rod 24 normally closing the dispensing port 12 and normally releasably en-gaged with the dasher 20 for operation of the dasher; and a knob 25 serving as a handle for the operating rod 24. All of these parts may be made of any suitable plastic material.

The shell 10 is formed at its open end with a pair of diametiically opposite flanges 26 and at its opposite end the dispensing port 12 yof the shell is provided with a surrounding tapered conical surface 28 for releasable engagement by interchangeable nozzles or needles, -for example a nozzle 30 shown in FIG. 9.

The lmain plunger 14 comprises an elongated body with an axial bore forming the smaller compartment 15. Preferably the main plunger has a pis-ton portion 32 equipped with two O-rings 34 and has a tubular shank portion 35 that is of lreduced diameter and is provided with four radial guide vanes 36 for cooperation with the internal A surface Iof. the shell 1G. The outer end of the main plunger 14 is formedwith a ange 38 to facilitate manual operation of the plunger. The secondary plunger 18 maybe provided with a pair of O-rings 40 and may be formed with a head or outer knob 42 to facilitate manual operation for displacing the smaller second ingredient into the main compartment 11.

The dasher 20 may have four radial vanes44 interconnected by an integral ring 45. The previously Vmentioned small plug 22 is an axial extension of the dasher and is dimensioned to fit tightly in the inner port 16. Preferably both the inner port16 and the small plug 22 are slightly tapered. As shown in FIG. 2 the dasher 20 has a threaded axial socket 48 that is normally engaged by the inner threaded end of the retractable operating rod 24.

The outer knob 25 may be mounted on the outer end of the retractable rod 24 by a forced lit and may be formed with external longitudinal ribs 54 and circumferential ribs 55 to facilitate manual gripping of the knob. The knob 25 is further formed with a cavity 56 which is tapered for releasable frictional engagement with the external tapered conical sui-face 28 at the dispensing port of the shell.

The manner in which the device operates to serve its purpose may` be readily understood from the foregoing description. FIGS. l and 2 show the device as assembled to serve as a package for handling, storing and shipping the two ingredients with the two ingredients completely isolated from each other. The rst or base ingredient occupies the shell 10 in the first compartment 11 between the leading end of the main plunger 14 and the dispensing port 12. The main plunger 14 a'buts the dasher 20 on the inner end of the operating rod 24 and it is apparent that the effective frictional engagement of the knob 25 with the tapered surface 28 of the shell 10 serves to lock the operating rod 24. Thus the operating rod 24 normally blocks the path of inward movement of the main plunger 14 and in addition closes the dispensing port 12 to provide a hydraulic block to inward movement of the main plunger.

The small plug 22 that is part of the dasher 20 is seated Y in the inner port 16 to keep the second ingredient in the smaller compartment 15 completely isolated from the tirst ingredient. At the same time, the presence of the operating rod 24 seals the dispensing port 12 to confine the base ingredient in the main compartment.

The first step in operating the device for intermixing and dispensing the two ingredients is to manipulate the knob 25 to free the knob from the tapered surface 28 and to retract the dasher 20 sutiiciently to withdraw the small plug 22 from the inner port 16, the parts then being in the positions shown in FIG. 6.

The next step illustrated by FIG. 7 is to depress the secondary plunger 18 by means of the outer knob 42 to displace the second minor ingredient from the smaller compartment 15 through the inner port 16 into the larger compartment 11. Since the inner port 16 is of restricted cross section and the minor ingredient is usually of low viscosity, the advance of the secondary plunger` causes the minor ingredient to be projected as a high velocity stream which effectively penetrates the major ingredient in the main compartment 11. The operating movement of the secondary plunger 18 increases the volume of material in the main compartment 11 and consequently causes the main plunger 14 to retract correspondingly/'since,theV

operating rod 24 keeps the dispensing port 12 sealed.

The next step is to reciprocate the dasher 20 vigorously by means of the knob 25 for thorough intermixture of the two ingredients, this step being illustrated in FIG. 8. When the two ingredients are thoroughly intermixed, the operating rod 24 is disengaged from the dasher 20 and is completely Withdrawn from the dispensing port 12. To disengage the operating rod from the dasher it is merely necessary to rotate the operating rod counterclockwise by means of the knob 25 while keeping the dasher from rotating, for example by squeezing the shell against the dasher. In this regard a' feature of the illustrated embodiment of the invention is the provision of a small lug or projection 58 inside the shell 10 near its leading end for engagement by a radial vane 44 of the dasher to keep the dasher from rotating when the operating rod is being disengaged from the dasher.

After the operating rod 24 is unscrewed from the dasher the operating rod is completely retracted to open the dispensing port 12. A suitable nozzle or needle 30 may be then mounted on the tapered surface 28 at the leading end of the shell and the main plunger may be depressed to expel the intermixed ingredients as shown in FIG. 9.

Because of the substantial length of the tapered surface 28 that is engaged by the knob 25 and because of theV low angle of taper of the surface, the knob may be depended upon to remain in tenacious engagement with the tapered surface throughout the handling, storing and shipping of the device. Notwithstanding the effectiveness with which the knob engages te tapered surface, however, the knob may be easily maneuvered free from the tapered surface by a slight twist.

It is apparent that the volume of the base composition in the first compartment 11 may be easily fifty times the volume of the second ingredient in the smaller compartment 15. It is to be noted that normally a substantial portion of the plunger 14 is telescoped into the shell 10 to make the plunger rigid relative to the shell and in like manner a substantial portion of the secondary plunger 18 extends into the main plunger to make the secondary plunger rigid relative to the main plunger. It is also apparent that since the parts may be readily molded from plastic material, the two-compartment syringe may be relatively inexpensive to make it practical to discard the device after a single use'. FIG. 9a shows how a cap 25a may be substituted for the knob 25 to avoid the necessity of accurately dimensioning the rod 24 with the knob 25 thereon. The necessity for accurate dirnensioning arises from the `fact that an accurately predetermined volume of material is placed in the iirst compartment 11 and from the further fact that the small plug 22 on the end of the rod member 24 must seat in the inner port 16 simultaneously with the seating of the tapered axial surface 28 in the tapered cavity 56 of theplunger 25. lf the rod 24 is too short for the quantity of liquid in the rst compartment 11, the seating of the tapered surface 28 in the cavityV 56 of the knob will occur without the small plug 22 seating in the inner port 16. On the other hand, if the rod member 24 is too long, the small plug 22 will seat in the inner port 16 before the tapered surface 28 seats in the cavity 56 of the knob 25, and if the rod member 24 is then advanced far enough for the tapered surface 28 to seat in the cavity 56,v the piston portion 32 of the main plunger 14 will be retracted to result in a' void or vacuum in the first cornpartment 11. Y

In FIG. 9a a handle means in the form of cap 25a is substituted for the knob 25. The cap has a cylindrical skirt 51, the inside diameter of which is slightly larger than the outside diameter of the shell 16. Normally the cylindrical skirt 51 telescopes over the shell 10 with the cap 25a enclosing and protecting the dispensing port and the tapered conical surface 28. Thus the cap 25a does not limit the axial inward movement of the rod member 24. It is readily apparent that the substitution of the cap 25a for the knob 25 permits substantial Vtolerance in the length of the rod member 24.

The rod member 24 should extend through dispensing port 12 of the shell 10 in a uid tight manner. For this purpose the dispensing port is of the configuration shown in FIG. 9a wherein the dispensing port is formed with an inner circumferential rib or sealing land 52 to embrace the rod member 24 in a iluid tight manner.

Turning to the second embodiment of the invention shown in FIGS. 10 to 13, which contains three ingredients separated from each other instead of two ingredients, the structure is largely similar to the structure of the irst embodiment of the invention as indicated by the use of corresponding numerals to indicate corresponding parts.

In the new construction a slightly modied main plunger 14a is substituted for the previously described primary plunger 14 and a secondary plunger 18a is substituted for the secondary plunger 18. The main plunger 14a is provided with the usual slightly tapered inner port 16 and, as shown in FIG. 13, the interior of the primary plunger at its inner end is formed with radial grooves 59 to facilitate displacement of material from the second compartment 15a into the main compartment 11.

The substituted secondary plunger 18a is hollow to store the third ingredient and for this purpose is formed with an axial bore 6G that extends throughout its length. The inner end of the axial bore 60 is enlarged to form a valve seat 62 for a ball valve member 64 which may be made of a suitable plastic. It is contemplated that the ball member will be wedged into the valve seat under suicient diametrical compression to form a seal for isolating the material in the axial bore 60 in the secondary plunger 18a from the material inside the main plunger 14a.

The third ingredient is confined in the axial bore 6) between the ball valve member 64 and a third small diameter plunger 65 that is slidingly mounted in the axial bore. The third plunger 65 is formed with a knob 68 on its outer end which, as shown in FIG. 10', is normally retracted from the knob 42a of the secondary plunger 18a. It is apparent that the second embodiment of the invention has the usual first or main compartment 11 formed by the shell 10, the usual second smaller compartment 15a formed by the secondary plunger 18a and, in addition, has a third smaller compartment 70 in the secondary plunger 18a, the third compartment being the portion of the axial bore 60 between the ball valve member 64 and the inner end of the third plunger 65.

In a typical use of the second embodiment of the invention, the main compartment 11 contains a base composition as previously described but the catalyst for activating the base composition is divided with some of its constituents in the second compartment 15a and the lremaining constituents in the third compartment 70. With constituents of the catalyst separated in this manner the package has an indenite shelf life.

Our description in specific detail of the selected embodiment of the invention will suggest various changes, substitutions and other departures from our disclosure within the spirit and scope of the appended claims.

We claim:

1. A dual compartment container for separately storing twoA ingredients, subsequently mixing the two ingredients and later dispensing the mixture, comprising:

a plurality of members of progressively dierent diameters telescoped together,

the outermost member being a cylindrical member forming a main compartment to contain a main ingredient, said main compartment being open at one end and having a dispensing port at the other end,

the remaining members closing said one nd of the main compartment and being manually movable relative to the outermost member towards said dispensing port to dispense the contents of the main compartment;

means normally closing said dispensing port, said closing means being manually operable to open the dispensing port,

rod means normally extending through said dispensing Y port to close the dispensing port; and

means operable by said rod means to open and close said inner port.

2. A combination as set forth in claim 1 in which the dasher means in the main compartment is releasably connected to said extending means.

3. Means for separately storing two ingredients, subsequently intermixing the two ingredients and then dispensing the mixture, comprising:

a main container to hold a first ingredient, said main container being open at one end and having a dispensing port at the other end;

plunger means mounted in the open end of said container and spanning the interior of the container, said plunger means being movable'towards said port to expel the contents of the main container through the port,

said plunger means having a passage therethrough to serve as an auxiliary container for a secondv ingredient, the inner end of said passage communicating with the interior of the main container;

an auxiliary plunger slidingly mounted in said passage and closing the outer end of the passage, said plunger being movable towards the inner end of the passage to transfer the second ingredient to the main container;

manually releasable means normally closing the inner end of said passage to isolate the two ingredients Y from each other;

dasher means in said main container to mix the Vtwo ingredients together; and operating means extending from the exterior of the main container through said dispensing port to reciprocate said dasher, said operating means normally closing said dispensing port and being retractable to open the dispensing port. Y 4. A combination as set forth in claim 3 which includes means to releasably connect said operating means to the main container to -maintain the operating means at an inner position until the time arrives for intermixing the two ingredients.

5. A combination as set forth in claim 4 in which said connecting means is a knob on the outer end of the operating means having a cavity for releasably embracing a portion` of the shell.

6. Means for separately storing two ingredients, subsequently intermixing the two ingredients and then dispensing the mixture, comprising:

a main container for one ingredient open at one end and formed with a dispensing port at the other end;

plunger means closing the other end of the container Vand movable towards said dispensing port to dispense the contents of the main container,

said plunger means being hollow to contain a second ingredient and having an inner port for communication with the main container;

means normally closing said inner port to isolate the second ingredient from the rst ingredient, said closing means being manually operable to open the inner t port;

means to displace the second ingredient from the interior of the plunger means through said inner port into the main container;

dasher means in the main container to mix the two ingredients together; and

, 8 means retractably extending into the main container through the dispensing port to normally close the dispensing port, v said retractable means being releasably connected to the dasher means for operation thereof. 7. A combination as sety forth in claim 6 in which the retractable means normally screwthreadedlyV engagesvthe dasher means; and

in which a projection on the inner wally of the main Icontainer is positioned to Vengage the dasher means to prevent rotation thereof to permit the retractable means toV be rotatedv out of engagement with the dasher means. f 8. A combination as set forth in claim 6 in which th means that normally closes the inner port is unitaryA with the dasher means for operation by the retractable means.

9.k Means for separately storing two ingredients,Y subsequently intermixing the two ingredients and then dispensing the mixture, comprising:

a shell to conne the first ingredient, said shell having at one end a dispensing port with an exterior tapered surface; y Y

a main plungerrclosing the other end of the shell with the outer end of the main plunger protruding from the shell, said outer end portion having radially posi-l tioned longitudinal guide fins in sliding engagement with the interior of the shell, said main plunger being movable towards the dispensingrport to dispense the content of the shell through the dispensing port,

said main plunger being hollow to contain the second ingredient and having an inner port for transferring the first ingredient into the shell;

an auxiliary plunger extending into the outer end of the main plunger for manual displacement of the first ingredient through the inner port into the shell;

dasher means inside theishell to mix the two ingredients together;

rod means retractably extending into the interior of the shell through said dispensing port and normally closing the dispensing port, V

said rod means being releasably connected to the dasher means for manual operation thereof;

a plug unitary with the dasher means and normally seated in the inner port to isolate the iirst ingredient from the second "ingredient whereby retraction of the dasher means by the rod means opens therinne port; and Y Vmeans at the outer end of the rod means Vnormally frictionally engaging said tapered surface of the dispensing outlet to releasably immobilize the rod means at a position with said plug closing the transfer port.

10. A combination as set forth in claim 9 whichrincludes a separate nozzle for mounting on'the dispensing port in -frictional engagement with the tapered surface thereof.

11. Means for separately storing t-wo ingredients, sub-k sequenlty intermixing the two ingredients and then dispensing the mixture, comprising:

a shell to confine the li'rst ingredient, said shell having a dispensing port at one end; Y a main plungerV closing the other end of the shell and movable to expel the contents of the shell through the dispensing port, said main plunger being hollow to contain the second ingredient and having an inner -port for transferring the rst ingredient into the shell; an auxiliary plunger extending into the outer end of the main plunger'for manual displacement -of the first ingredient through the inner port into the shell; dasher means inside the shell to mix the two ingredients together; Y rod means re'tractably extending into the interior of the shell through the dispensing port and normally `closing the dispensing port,

9 said rod means being releasably connected to the dasher means for manual operation thereof; and means normally closing said inner port, said closing means being operable by the rod means to open the inner port.

12. Means for separately storing two ingredients, subsequently intermixing the two ingredients and then dispensing the mixture, comprising:

a shell to confine the first ingredient, said shell having a dispensing port at one end;

a main plunger closing the other end of the shell, said main plunger being hollow to contain the second ingredient and having an inner -port for transferring the first ingredient into the shell;

annular sealing means effective between the main plunger and the shell;

an auxiliary plunger extending into the outer end of the main plunger for manual displacement of the first ingredient into the shell;

annular sealing means effective between the auxiliary plunger and the main plunger;

manually retractable plug means normally closing said inner port;

dasher means inside the shell to mix the two ingredients together; and

rod means extending into the interior of the shell through said dispensing outlet and normally closing the dispensing outlet, said rod means being retractable through the dispensing port and being releasably connected to the dasher means for manual operation thereof.

13. In a device of the character described for use with a separate nozzle for dispensing a iiuent material, the combination of:

a container having a dispensing port with an external surface shaped for releasable engagement by the nozzle;

dasher means in the container for agitating the uent material;

a separate operating member extending into said dispensing port and releasably connected to the dasher means for operation thereof, said operating member normally closing the dispensing port and being retractable to open the dispensing port; and

means on the outer end of the operating member to releasably engage said external surface to retain the operating member in the dispensing port.

14. In a device of the character described, the combination of:

a container means having a first compartment to contain a first ingredient and a second compartment to contain a second ingredient,

said first compartment having a first dispensing port, said second compartment having a second port for communication with the first compartment;

means normally extending through said dispensing port into said second port to close both of the ports,

said extending means being partially retractable to open the second port while keeping the first port closed and being completely retractable to open both ports, said second compartment being manually contractible to expel the second ingredient through the second port into the rst compartment; and

means to expel the contents of said first compartment through said dispensing port.

15. A combination as set forth in claim 14 which includes means cooperative with said container means to releasably hold said extending means in its normal position.

16. In a device of the character described, the combination of:

a container having a first compartment to contain a first ingredient and a second compartment to contain a second ingredient, said first compartment having a first dispensing port,

1@ said second compartment having `a second port for communication with the first compartment,

said dispensing port having an external surface for releasable engagement by a separate dispensing nozzle;

means normally extending through said dispensing port into said second port to close both of the ports,

said extending means being partially retractable from its normal position to open the second port while keeping the first port closed and being completely retractable to open both ports, said second compartment being manually contractible to expel the second ingredient through the second port into the first compartment;

means to releasably engage said external surface of the dispensing port to releasably hold said extending means in its normal position; and

means to expel the contents of said first compartment through said dispensing port.

17. A combination as set forth in claim 16 in which said external surface is a tapered surface and said cooperative means is a knob on the outer end of the extending means, said knob having a tapered cavity for frictional engagement with said tapered surface.

1S. A multiple-compartment container for separately storing three ingredients, and later dispensing the three ingredients, comprising:

a plurality of members of progressively different diameters telescoped together,

the outermost member of said plurality of members being a cylindrical member forming a first compartment to contain a first ingredient, said first compartment being open at one end and having a dispensing port at the other end;

means normally closing said dispensing port, said closing means being manually operable to open the dispensing port,

a second member of the plurality of members being slidable in the first compartment to expel the content of the first compartment through the dispensing port, said second member being hollow to form a second compartment to contain a second ingredient,

a third member of the plurality of members lbeing slidable in the second compartment to displace the content of the second compartment into the first compartment,

said third member being hollow to form a third compartment, said third compartment being contractible to displace the contents thereof into the second compartment; and

means normally cutting off communication between the third compartment and the second compartment, said cutting off means being manually operable to place the third compartment in communication with the second compartment.

19. A combination as set forth in claim 18 which includes manually operable means in the first compartment to mix the ingredients together.

2t?. A combination as set forth in claim 13 in which said means to cut off communication between the third compartment and the second compartment comprises a closure member adapted to be unseated by the pressure created in the third compartment when the third compartment is contracted.

21. In a device of the character described, the combination of:

a container having a first compartment to contain a first ingredient and a second compartment to contain a second ingredient,

said first compartment having a first dispensing port, said second compartment having a second port for communication with the first compartment,

said second compartment being manually contractible to displace its content through said second port into the first compartment and said first compartment being manually contractible to extrnde its content through said dispensing port;

mixing means including a dasher in said rst compartment and a rod member connected to the dasher for manual operation thereof, said rod member normally extending through said dispensing port to close the dispensing port, said rod member being releasable from the dasher for retraction of the rod member to open the dispensing port;

means carried by said mixing means to normally close said second port and to open the second port in response to retraction of the rod member; and

handle means for the outer end of said rod member, said handle means being adapted to telescope over the outer peripheral surface of said container thereby to enclose the portion of the container around `the dispensing port.

22. A combination as set forth in claim 2-1 in which said container is made of plastic material and is formed with an inner circumferential rib at said dispensing port to embrace said rod member to seal olf the dispensing port and to frictionally retain the rod member.

23. A combination as set forth in claim 21 in which said container is shaped at said dispensing port with an outer tapered surface to permit a dispensing nozzle to be mounted on the container means, said tapered surface being normal-ly enclosed by the telescoping of said handle means over the outer peripheral surface of the container.

References Cited UNTED STATES PATENTS 2,665,687 1/ 1954 -BroWn 12S-218 3,028,052 4/ 1962 :Archer 222-136 3,082,914 3/ 1963 Gill 222-135 3,144,966 8/1964 Cook 222-136 3,197,067 7/196-5 Rataczak 222-386 X STANLEY H. TOLLBERG, Primary Examiner.

US3370754A 1966-12-21 1966-12-21 Syringe for mixing and dispensing two ingredients Expired - Lifetime US3370754A (en)

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Cited By (55)

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US3563415A (en) * 1969-06-04 1971-02-16 Multi Drop Adapter Corp Multidrop adapter
US3610297A (en) * 1968-08-28 1971-10-05 Pfizer Dual-chamber liquid ejector and filling connector
US3680558A (en) * 1970-05-27 1972-08-01 Robert F Kapelowitz Syringe with multiple compartments
US3707146A (en) * 1967-03-07 1972-12-26 Prod Res & Chem Corp Means to inject a plastic into a cavity to produce a replica thereof
US3739947A (en) * 1969-08-01 1973-06-19 E Baumann Storing and mixing receptacle
US3835835A (en) * 1972-11-07 1974-09-17 Richardson Merrell Inc Two compartment locking sampling syringe
US3938513A (en) * 1974-01-03 1976-02-17 Hargest Thomas S Syringe filter and valve combination
US4171698A (en) * 1977-08-15 1979-10-23 Abbott Laboratories Prefilled two-compartment syringe
DE2918121A1 (en) * 1978-05-01 1979-11-15 Steven R Anderson Composite cartridge and device for metering of the contents to be pressed out
US4188949A (en) * 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
DE3022389A1 (en) * 1980-06-14 1981-12-24 Ara Werk Kraemer & Co Aerosol can or the like. to issue standing of pressurized fluids
US4366919A (en) * 1978-05-01 1983-01-04 Coaxial Cartridges, Inc. Composite cartridge and device for metering extrusion of contents
FR2528706A1 (en) * 1982-06-18 1983-12-23 Dessapt Bernard IMPROVED syringe has dual compartment
US4476866A (en) * 1982-08-06 1984-10-16 Thomas J. Fogarty Combined large and small bore syringe
FR2575083A1 (en) * 1984-12-21 1986-06-27 Claude Bosson mixing syringe honed to double
EP0299433A1 (en) * 1987-07-15 1989-01-18 Alfred Fischbach Kunststoffspritzgusswerk Device for mixing or homogeneiring the content of a cartridge
US4808006A (en) * 1985-12-06 1989-02-28 Intecser S.A. Device to maintain separate until the moment of use and then to mix two different substances within a container, particularly two-component resins
US4826047A (en) * 1988-06-30 1989-05-02 E. I. Du Pont De Nemours And Company Hand held dispenser for mixing and dispensing two viscous components
WO1990004952A1 (en) * 1987-05-11 1990-05-17 Lueth Stefan Device for preparing a two-component mixture
FR2645016A1 (en) * 1989-03-31 1990-10-05 Gerard Ramond Installation for automatic preparation of electrically conductive casts forming cutaneous electrodes
DE8907336U1 (en) * 1989-06-15 1990-10-18 Espe Stiftung & Co Produktions- Und Vertriebs Kg, 8031 Seefeld, De
US5127548A (en) * 1990-02-21 1992-07-07 Valois Medicinal spray device with two substance compartments separated by puncturable membrane
US5172807A (en) * 1991-09-30 1992-12-22 Centrix, Inc. Cement mixing capsule
US5286257A (en) * 1992-11-18 1994-02-15 Ultradent Products, Inc. Syringe apparatus with detachable mixing and delivery tip
US5301842A (en) * 1991-03-06 1994-04-12 Frank Ritter Multicomponent cartridge for plastic materials
US5630800A (en) * 1993-11-08 1997-05-20 Ferring Arzneimettel Gmbh Injection syringe for the missing and application of injection substances
US5918770A (en) * 1995-02-27 1999-07-06 Camm; James Owen Dual material dispenser comprising two containers in head to tail arrangement
WO2005018830A2 (en) 2003-08-21 2005-03-03 Mixpac Systems Ag Device and method for the storage, mixing and dispensing of components
US20050264062A1 (en) * 2004-04-30 2005-12-01 Chicco Usa, Inc. Infant travel system
US7007829B1 (en) * 2003-02-19 2006-03-07 Chief Packaging Company, Llc Hollow handle push-up piston for a food container
US20060054636A1 (en) * 2004-09-10 2006-03-16 Brennan Robert C Dual fluid cartridge for storing and dispensing fluids in unequal ratios
US20060144858A1 (en) * 2003-06-09 2006-07-06 Brennan Robert C Dual fluid cartridge assembly
US20060151530A1 (en) * 2005-01-08 2006-07-13 Horner Terry A Dual fluid cartridge with reduced fluid waste
US20070228076A1 (en) * 2006-03-29 2007-10-04 Horner Terry A Single dose dual fluid cartridge for use with hand-held applicators
US20070250013A1 (en) * 2006-03-31 2007-10-25 Brennan Robert C Self-contained single dose dual fluid dispenser
US20070246482A1 (en) * 2006-03-20 2007-10-25 Goldberg Marc A Propellant actuated dual fluid cartridge
US20080065088A1 (en) * 2006-09-07 2008-03-13 Wyeth Bone Cement Mixing Systems and Related Methods
US20080144433A1 (en) * 2006-12-13 2008-06-19 Renfro Charles K Multi-chambered fluid mixing apparatus and method
US20090012497A1 (en) * 2006-12-29 2009-01-08 Medrad, Inc. Systems and methods of delivering a dilated slurry to a patient
US20090043282A1 (en) * 2005-04-29 2009-02-12 Wyeth Drug Delivery Devices and Related Components, Systems and Methods
US20090112157A1 (en) * 2007-10-31 2009-04-30 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
CN100571896C (en) 2005-07-01 2009-12-23 药物混合系统股份公司 Multi-component dispensing device with valve assembly
US20090314803A1 (en) * 2006-08-22 2009-12-24 Medmix Systems Ag Device and method for storing, mixing and dispensing components
WO2012140160A1 (en) * 2011-04-15 2012-10-18 Transcodent GmbH & Co. KG Dispensing container for dental compound
JP2013240582A (en) * 2012-05-07 2013-12-05 Heraeus Medical Gmbh Mixing device for multi-component systems
US20140088498A1 (en) * 2012-09-21 2014-03-27 Merit Medical Systems, Inc. Variable displacement inflation devices and methods of use
US8931665B2 (en) * 2012-11-06 2015-01-13 Amit Gold Multi-compartment apparatus for in-situ mixing of a plurality of components before use
EP2349547A4 (en) * 2008-10-31 2015-06-24 Warsaw Orthopedic Inc Multi-chamber mixing system
US20160045283A1 (en) * 2013-03-26 2016-02-18 3M Innovative Properties Company A plunger assembly and a capsule for dispensing a dental material
US9452263B2 (en) 2011-09-16 2016-09-27 Becton Dickinson France Plunger rod with dose setting means and injection device
WO2016188096A1 (en) * 2015-05-27 2016-12-01 Abon Biopharm(Hangzhou) Co. Ltd. A mixing device
US20170072141A1 (en) * 2013-05-22 2017-03-16 Warren Robinson Syringe Assembly for Storing, Mixing, and Releasing Two Reactive Compounds
US20170252715A1 (en) * 2016-03-03 2017-09-07 Heraeus Medical Gmbh Storage and mixing system for pasty cement components and method therefor
USD807502S1 (en) 2015-03-02 2018-01-09 Neomed, Inc. Enteral syringe
US10010362B2 (en) * 2014-02-03 2018-07-03 Heraeus Medical Gmbh Device for storing and mixing bone cement

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Cited By (82)

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US3707146A (en) * 1967-03-07 1972-12-26 Prod Res & Chem Corp Means to inject a plastic into a cavity to produce a replica thereof
US3610297A (en) * 1968-08-28 1971-10-05 Pfizer Dual-chamber liquid ejector and filling connector
US3563415A (en) * 1969-06-04 1971-02-16 Multi Drop Adapter Corp Multidrop adapter
US3739947A (en) * 1969-08-01 1973-06-19 E Baumann Storing and mixing receptacle
US3680558A (en) * 1970-05-27 1972-08-01 Robert F Kapelowitz Syringe with multiple compartments
US3835835A (en) * 1972-11-07 1974-09-17 Richardson Merrell Inc Two compartment locking sampling syringe
US3938513A (en) * 1974-01-03 1976-02-17 Hargest Thomas S Syringe filter and valve combination
US4188949A (en) * 1977-07-05 1980-02-19 Becton, Dickinson & Company Sequential injection syringe
US4171698A (en) * 1977-08-15 1979-10-23 Abbott Laboratories Prefilled two-compartment syringe
DE2918121A1 (en) * 1978-05-01 1979-11-15 Steven R Anderson Composite cartridge and device for metering of the contents to be pressed out
US4366919A (en) * 1978-05-01 1983-01-04 Coaxial Cartridges, Inc. Composite cartridge and device for metering extrusion of contents
DE3022389A1 (en) * 1980-06-14 1981-12-24 Ara Werk Kraemer & Co Aerosol can or the like. to issue standing of pressurized fluids
FR2528706A1 (en) * 1982-06-18 1983-12-23 Dessapt Bernard IMPROVED syringe has dual compartment
WO1984000011A1 (en) * 1982-06-18 1984-01-05 Bernard Dessapt Improved syringe with double compartment
US4476866A (en) * 1982-08-06 1984-10-16 Thomas J. Fogarty Combined large and small bore syringe
FR2575083A1 (en) * 1984-12-21 1986-06-27 Claude Bosson mixing syringe honed to double
EP0188981A1 (en) * 1984-12-21 1986-07-30 Claude Bosson Double chamber mixing syringe
US4808006A (en) * 1985-12-06 1989-02-28 Intecser S.A. Device to maintain separate until the moment of use and then to mix two different substances within a container, particularly two-component resins
WO1990004952A1 (en) * 1987-05-11 1990-05-17 Lueth Stefan Device for preparing a two-component mixture
WO1989000536A1 (en) * 1987-07-15 1989-01-26 Alfred Fischbach Kg Kunststoff-Spritzgusswerk Mixing device
EP0299433A1 (en) * 1987-07-15 1989-01-18 Alfred Fischbach Kunststoffspritzgusswerk Device for mixing or homogeneiring the content of a cartridge
US4826047A (en) * 1988-06-30 1989-05-02 E. I. Du Pont De Nemours And Company Hand held dispenser for mixing and dispensing two viscous components
FR2645016A1 (en) * 1989-03-31 1990-10-05 Gerard Ramond Installation for automatic preparation of electrically conductive casts forming cutaneous electrodes
DE8907336U1 (en) * 1989-06-15 1990-10-18 Espe Stiftung & Co Produktions- Und Vertriebs Kg, 8031 Seefeld, De
US5058770A (en) * 1989-06-15 1991-10-22 Thera Patent Gmbh & Co. Kg Gesellschaft Fuer Industrielle Schutzrechte Container for substances prepared by mixing components
US5127548A (en) * 1990-02-21 1992-07-07 Valois Medicinal spray device with two substance compartments separated by puncturable membrane
US5301842A (en) * 1991-03-06 1994-04-12 Frank Ritter Multicomponent cartridge for plastic materials
US5172807A (en) * 1991-09-30 1992-12-22 Centrix, Inc. Cement mixing capsule
US5286257A (en) * 1992-11-18 1994-02-15 Ultradent Products, Inc. Syringe apparatus with detachable mixing and delivery tip
US5630800A (en) * 1993-11-08 1997-05-20 Ferring Arzneimettel Gmbh Injection syringe for the missing and application of injection substances
US5918770A (en) * 1995-02-27 1999-07-06 Camm; James Owen Dual material dispenser comprising two containers in head to tail arrangement
US7007829B1 (en) * 2003-02-19 2006-03-07 Chief Packaging Company, Llc Hollow handle push-up piston for a food container
US7506783B2 (en) 2003-06-09 2009-03-24 Nordson Corporation Dual fluid cartridge assembly
US20060144858A1 (en) * 2003-06-09 2006-07-06 Brennan Robert C Dual fluid cartridge assembly
WO2005018830A2 (en) 2003-08-21 2005-03-03 Mixpac Systems Ag Device and method for the storage, mixing and dispensing of components
US9522615B2 (en) 2004-04-30 2016-12-20 Artsana Usa, Inc. Travel seat engaging system
US9403449B2 (en) 2004-04-30 2016-08-02 Artsana Usa, Inc. System for engaging multi-component carseat
US8915547B2 (en) 2004-04-30 2014-12-23 Artsana Usa, Inc. System for engaging multi-component carseat
US8864166B2 (en) 2004-04-30 2014-10-21 Artsana Usa, Inc. Travel seat engaging system
US8056975B2 (en) 2004-04-30 2011-11-15 Artsana Usa, Inc. Travel seat restraint system
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US8393679B2 (en) 2004-04-30 2013-03-12 Artsana Usa, Inc. System for engaging multi-component carseat
US20060054636A1 (en) * 2004-09-10 2006-03-16 Brennan Robert C Dual fluid cartridge for storing and dispensing fluids in unequal ratios
US7237693B2 (en) 2004-09-10 2007-07-03 Tah Industries, Inc. Dual fluid cartridge for storing and dispensing fluids in unequal ratios
US7497355B2 (en) 2005-01-08 2009-03-03 Nordson Corporation Dual fluid cartridge with reduced fluid waste
US20060151530A1 (en) * 2005-01-08 2006-07-13 Horner Terry A Dual fluid cartridge with reduced fluid waste
US20090043282A1 (en) * 2005-04-29 2009-02-12 Wyeth Drug Delivery Devices and Related Components, Systems and Methods
CN100571896C (en) 2005-07-01 2009-12-23 药物混合系统股份公司 Multi-component dispensing device with valve assembly
US20070246482A1 (en) * 2006-03-20 2007-10-25 Goldberg Marc A Propellant actuated dual fluid cartridge
US7481333B2 (en) 2006-03-20 2009-01-27 Nordson Corporation Propellant actuated dual fluid cartridge
US20070228076A1 (en) * 2006-03-29 2007-10-04 Horner Terry A Single dose dual fluid cartridge for use with hand-held applicators
US7748567B2 (en) 2006-03-29 2010-07-06 Nordson Corporation Single dose dual fluid cartridge for use with hand-held applicators
US20070250013A1 (en) * 2006-03-31 2007-10-25 Brennan Robert C Self-contained single dose dual fluid dispenser
US8256646B2 (en) * 2006-08-22 2012-09-04 Medmix Systems Ag Device and method for storing, mixing and dispensing components
US20090314803A1 (en) * 2006-08-22 2009-12-24 Medmix Systems Ag Device and method for storing, mixing and dispensing components
US20080065088A1 (en) * 2006-09-07 2008-03-13 Wyeth Bone Cement Mixing Systems and Related Methods
US20080144433A1 (en) * 2006-12-13 2008-06-19 Renfro Charles K Multi-chambered fluid mixing apparatus and method
US8132958B2 (en) * 2006-12-13 2012-03-13 Renfro Charles K Multi-chambered fluid mixing apparatus and method
US20090012497A1 (en) * 2006-12-29 2009-01-08 Medrad, Inc. Systems and methods of delivering a dilated slurry to a patient
US9814827B2 (en) 2006-12-29 2017-11-14 Bayer Healthcare Llc Systems and methods of delivering a dilated slurry to a patient
US8382704B2 (en) 2006-12-29 2013-02-26 Medrad, Inc. Systems and methods of delivering a dilated slurry to a patient
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US20090112157A1 (en) * 2007-10-31 2009-04-30 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
JP2011502027A (en) * 2007-10-31 2011-01-20 ウルトラデント プロダクツ インコーポレイテッド Mixing device comprising a plunge mixing member for use with a syringe
US7879002B2 (en) * 2007-10-31 2011-02-01 Ultradent Products, Inc. Mixing device including a plunging mixing member for use with a syringe
EP2349547A4 (en) * 2008-10-31 2015-06-24 Warsaw Orthopedic Inc Multi-chamber mixing system
WO2012140160A1 (en) * 2011-04-15 2012-10-18 Transcodent GmbH & Co. KG Dispensing container for dental compound
US9452263B2 (en) 2011-09-16 2016-09-27 Becton Dickinson France Plunger rod with dose setting means and injection device
US8992071B2 (en) 2012-05-07 2015-03-31 Heraeus Medical Gmbh Mixing device for multi-component systems
JP2013240582A (en) * 2012-05-07 2013-12-05 Heraeus Medical Gmbh Mixing device for multi-component systems
US9452279B2 (en) * 2012-09-21 2016-09-27 Merit Medical Systems, Inc. Variable displacement inflation devices and methods of use
US20140088498A1 (en) * 2012-09-21 2014-03-27 Merit Medical Systems, Inc. Variable displacement inflation devices and methods of use
US8931665B2 (en) * 2012-11-06 2015-01-13 Amit Gold Multi-compartment apparatus for in-situ mixing of a plurality of components before use
US20160045283A1 (en) * 2013-03-26 2016-02-18 3M Innovative Properties Company A plunger assembly and a capsule for dispensing a dental material
US20170072141A1 (en) * 2013-05-22 2017-03-16 Warren Robinson Syringe Assembly for Storing, Mixing, and Releasing Two Reactive Compounds
US10010362B2 (en) * 2014-02-03 2018-07-03 Heraeus Medical Gmbh Device for storing and mixing bone cement
USD807502S1 (en) 2015-03-02 2018-01-09 Neomed, Inc. Enteral syringe
WO2016188096A1 (en) * 2015-05-27 2016-12-01 Abon Biopharm(Hangzhou) Co. Ltd. A mixing device
US20170252715A1 (en) * 2016-03-03 2017-09-07 Heraeus Medical Gmbh Storage and mixing system for pasty cement components and method therefor
US10086343B2 (en) * 2016-03-03 2018-10-02 Heraeus Medical Gmbh Storage and mixing system for pasty cement components and method therefor

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