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Micrometer controlled leak-proof syringe

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US3281023A
US3281023A US44495165A US3281023A US 3281023 A US3281023 A US 3281023A US 44495165 A US44495165 A US 44495165A US 3281023 A US3281023 A US 3281023A
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Prior art keywords
piston
barrel
seal
syringe
sleeve
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Stephen D Bruck
Ruth G Rector
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Stephen D Bruck
Ruth G Rector
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31591Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513Piston constructions to improve sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31586Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31555Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31561Mechanically operated dose setting member using freely adjustable volume steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31563Mechanically operated dose setting member interacting with a displaceable stop member

Description

Oct. 25, 1966 s. D. BRUcK ETAL 3,281,023

MICROMETER GONTROLLED LEAK-PROOF SYRINGE Filed March 51, 1965 5 nxn, Y m mm M N 6A R Qm/Qm/ M, @Tux Wm n. www I A \Q\\\\\ www Y. |n 5 nl .IMI DWG w x Mmm ww mm mm mm. EL bv DHLMM m EB T0 SRE N 6P." mm

Wm, QM.

AGENT United States Patent O 3,281,023 MICROMETER CONTROLLED LEAK-PROOF SYRINGE Stephen D. Bruck, Bethesda, Md., and Robert R. Rector,

deceased, late of Laurel, Md., by Ruth G. Rector, administratrix, Laurel, Md., assignors to the United States f America as represented by the Secretary of the Navy Filed Mar. 31, 1965, Ser. No. 444,951 Claims. (Cl. 222-390) The present invention relates t-o dispensers and more particularly to a micrometer controlled leak-proof syringe.

Those concerned with the development of syringes have long recognized the need for a syringe which is absolutely leak-proof, which can handle all kinds of corrosive and non-corrosive lluids and which can dispense an exact measured quantity of lluid with extreme accuracy.

There are, in general, two different types of syringes in use at the present time. The first type, commonly referred to as a hypodermic syringe in the medical eld, is comprised of a hollow tube or barrel, one end of which is open to admit a piston, and the other end of which is provided with a restricted orifice. A piston is slidably received within the open end of the barrel to provide a suction, when withdrawn during intake stroking, for introducing the fluid into the tube through the orifice and to eject the fluid therefrom during exhaust stroking when the piston is advanced inwardly toward the orifice. The second type, commonly referred to as a micrometer controlled syringe, is generally used when either `an extremely high pressure is required for forcing the lluid therefrom as, for example, in a grease gun, or when an exact measured quantity of fluid must be dispensed as, for example, in a laboratory instrument. This type of syringe generally comprises anouter tube or barrel having a restricted orifice at one end and a tapped bore at the other end. A piston having a threaded stem portion is disposed within the barrel with the stem thereof threadedly engaging the tapped bore in the barrel end so that the piston may be advanced into and withdrawn from the barrel by rotation of the piston stem.

Although such prior art micrometer controlled syringes have generally served the purpose, they have not proven entirely satisfactory under all conditions of service since considerable difficulty has been' experienced both in providing a positive seal between the rotatable piston and the outer barrel and in controlling, with a high degree of accuracy, the amount of iluid dispensed.

The Igeneral purpose, therefore, of the present invention is to provide a syringe which embraces all of the advantages of similarly employed prior art micrometer lcontrolled syringes and which possesses none of the aforedescribed disadvantages. To attain this purpose, the micrometer controlled syringe of the present invention utilizes both a unique non-rotatable piston seal and a novel inner sleeve fluid measurement device.

Accordingly, an object of the present invention is the provision of a syringe which has a completely leak-proof piston seal.

Another object is to provide a syringe having a rotatable piston with a non-rotatable piston seal thereon.

Still another object is to provide a syringe which may be used with all kinds of corrosive and non-corrosive fluids.

' A further object of the invention is the provision of a syringe which may be filled with, and which can dispense, an exact measured quantity of fluid.

ICC

Yet another object of the invention is the provision of a syringe which is characterized by simplicity of construction, low cost and ease of operation.

Other objects and many of the attendant advantages of this invention will be readily appreciated as the same becomes better understood by reference t-o the following detailed description when considered in connection with the accompanying drawings in which:

FIG. 1 is an elevation view of the syringe of the present invention;

FIG. 2 is an elevation view, in section, of the syringe shown in FIG. 1; and

FIG. 3 is an enlarged fragmentary sectional view of a portion of the syringe of the present invention.

Referring now to the drawings wherein like reference characters designate like or corresponding parts throughout the several views, there is Shown in FIGS. l and 2 a syringe 10 comprised of an outer cylindrical barrel 12 provided with precisely calibrated volume markings 13 thereon and having a tip 14 at one end. An outwardly extending annular radial flange 16 is provided at the other end. In addition, the tip 14 is provided with a restricted orifice 18 for conducting the iluid into and out of the barrel 12. A cylindrical sleeve 20 is coaxially disposed within the outer barrel 12 with one end thereof being Iprovided with a tapped bore 21 while the other end 22 is open. A clamp 24 having an annular flange 26 secured around the radiallyl extending barrel flange 18 and having a tapped bore 28 with a thumb screw 30 threadedly received therein is provided for releasably securing the sleeve 20 to the-outer cylindrical barrel 12. Alternatively, the clamp 24 may have a slot 25 provided therein so that it may be slipped over the barrel flange 18 for assembly or disassembly. A piston, indicated generally by reference character 32, is coaxially disposed within the outer cylindrical barrel 12 between theopen end of the Sleeve 20 and the end 31 0f the barrel 12. The piston i 32 is secured to a piston rod 34 having a threaded portion 36 for threadedly engaging the tapped bore 21 of the sleeve 20. A knob 38 is secured to the end of the piston rod 34 by a set screw 40.

As more clearly illustrated in FIG. 3, the piston 32 is comprised of a ilrst cylindrical disk 42 having first and second cylindrical recesses 43, 44 formed respectively in opposite faces thereof. The piston rod 34 is disposed within the rst recess 43 a-nd secured to the disk 42 by meansI of a pin 45. A second cylindrical disk 48, forming the Aforward face of the piston 32, has an integral axially extending stem portion 50 disposed in recess 44 and secured to the rst cylindrical disk by means of a pin 52. The inside face of the second cylindrical disk 48 is provided with an annular llat surface 54 and an inverse tapered wall `surface 56 joining the disk 48 to the stem portion 50 while lthe corresponding juxtaposed face of the first cylindrical disk 42 is provided with similar surfaces 57 and 58, respectively. An annular seal 60 is slightly compressed and disposed within the annular frusto-conical seat formed by the disks 42, 48 andthe stem 50.

The seal 60 is preferably fabricated from a fluorocarbon synthetic resin, e.g., tetrailuoroe-thylene, this type of resin commonly being known as Teflon, a registered trademark of E. I. du Pont de Nemours & Company, Incorporated, of Wilmington, Delaware. The outer barrel 12 is preferably formed of a transparent material, such as glass or the like, while the remaining parts are fabricated from either a metal, such as stainless steel, or a chemically inert plastic.

The syringe 10 of the present invention is prepared for lling by unscrewing the set screw 3,0 and by rotating the knob 38 until the piston 32 abuts the open end 22 of the sleeve 20. The piston 32 and the sleeve 20 are then advanced into the barrel 12 until the piston 32 abuts the end 31 thereof. The tip 14 of the syringe 10 is lthen irnmersed in the fluid to be dispensed and the sleeve and the pist-on 32 are partially withdrawn from the barrel 12 by pulling on the knob 38 until the desired volume of fluid, as indicated by volume mark-ings 13, is contained in the barrel 12. The set screw 30 is then screwed into the tapped bore 28 to securely lock the sleeve 20 to the outer barrel 12, thereby insuring that the quantity of fluid contained in the barrel 12 remains constant until the fluid is dispensed by rotation of .the knob 38.

As set forth hereinabove, difficulties have been encountered with prior art micrometer operated syringes in providing a positive seal between the rotating piston and the inside wall of :the barrel. In rthe present invention, this diiculty is overcome by providing a seal which does not rotate with the piston. This is accomplished by providing a larger frictional force between lthe seal 60 and the inside wall of the barre-l 12 than between the seal 60 and the pis-ton 32. Since .the frictional force between two relatively movable objects is proportional to the contacting surface area therebetween, the syringe of the present invention is configured so that .the contacting surface area between the seal 60 and the inside of the glass barrel 12 is sufiiciently larger than the total contacting surface area between Ithe seal 60 and both the frusto-conical seat 54, 56, 57, 58 and the stem 50 so as to maintain the seal stationary with respect to the rotating piston, thereby providing a positive seal. Furthermore, since the seal is fabricated from Teflon, the syringe may be used with all corrosive and non-corrosive fluids.

There has, therefore, been described a syringe which, due .to the construction of the inner sleeve 20 and the micrometer piston advancement means, can dispense an exact measured quantity of fiuid with'extreme accuracy and which, due to the construction of the Teflon seal assembly, provides a positive seal between the piston and the outer barrel which can be used with all types of fluids.

It should be understood, :of course, that the foregoing disclosure relates to only a preferred embodiment of the invention and that many modifications or alterations may be made therein without departing from the spirit and Ithe scope of the invention as set forth in the appended claims.

What is claimed is:

1. A micrometer controlled leak-proof syringe comprising:

an outer cylindrical barrel having a radially extending annular flange at one end and an orifice at the other end;

a cylindrical sleeve disposed within and coaxial with said barrel, said sleeve having a tapped bore at one end thereof;

a clamp engaging said barrel flange and having a thumb screw disposed in a tapped aperture therein, said thumb screw normally engaging said sleeve near the tapped bore end thereof for releasably securing said sleeve to said barrel;

a piston rod, a portion of which is coaxially disposed within said sleeve, said piston rod having a threaded lead screw portion for threadedly engaging said tapped bore in said sleeve, said piston rod having a knob secured thereto at one end;

a piston secured to the other end of said piston rod for rotational movement therewith, said piston having an annular peripheral frusto-conical groove therein;

seal means disposed in said groove, said seal means contacting the inside surface of said barrel; and

means for preventing rotation of said seal relative to isaid barrel as said piston is rotated;

whereby, 2.15 iiaid piston is advanced through said barrelv by rotation of said pis-ton rod, said seal does not rotate, thereby providing a positive seal between said piston and said barrel.

2. A syringe in accordance with claim 1 wherein:

said barrel is formed of glass', said piston is formed of stainless steel and said seal is formed of Teon.

3. A syringe in accordance with claim 2 wherein:

said piston is comprised of first and second cylindrical disks, Asaid second disk having an integral stern portion secured to said first disk, said first and second disks' having juxtaposed annular tapered wall portions defining an annular frusto-conical seat into which said Teon seal is disposed.

4. A syringe in accordance with claim 3 wherein:

said seal is configured and arranged so that the contacting surface area between said seal and said barrel is sufficiently large with respect to the contacting surface area between said seal and said piston rto prevent rotation of said seal as said piston rotates.

5. A micrometer controlled leak-proof syringe comprising:

an outer barrel formed of a transparent material;

a sleeve slidably disposed within said barrel, said sleeve extending throughout a substantial por-tion of the axial length of said barrel, said sleeve having a tapped bore at one end thereof;

means releasably securing said sleeve to said barrel;

a rotatable piston rod c-oaxially disposed within said barrel and threadedly engaging the tapped bore of said sleeve;

Aa rotatable piston secured to said piston rod and coaxially disposed within said barrel;

annular seal means disposed on said piston and contacting the inside surface -of said barrel; and

means to prevent rotation of said seal on said piston as said piston is rotated in said barrel.

6. A micrometer controlled syringe comprising:

an outer barrel;

means slidably mounted within said barrel and having a tapped bore disposed adjacent the end of said barrel;

a piston rod disposed in said barrel and threadedly engaging said tapped bore;

a piston secured to the end of said piston rod;

and seal means disposed around said pist-on in sealing engagement with said barrel.

7. A syringe in accordance with claim 6 wherein:

said seal means is fabricated from Tefion and is disposed in a peripheral groove in said piston.

8. A syringe in accordance with claim 6 wherein:

said slidably mounted means comprises a cylindrical sleeve.

9.r A syringe in accordance with claim 6 additionally means to prevent rotation of said seal means as said piston rod is rotated.

10. A micrometer type precision controlled leak-proof syringe comprising:

an outer cylindrical barrel having a stepped axial bore terminated by an elongated axial orifice portion of substantially reduced bore dimensions with respect to the major portion of the bore thereof;

a generally, hollow cylindrical sleeve disposed within and coaxial with said barrel, said sleeve having a threaded bore at one end thereof;

clamp means cooperating with the end portion of said barrel 'remote from said orifice portion, said clamp Vmean-s being disposed to normally engage said cylindrical sleeve adjacent the threaded bore end thereof for releasably securing said sleeve against relative movement with respect to said barrel;

a piston and piston rod member, a portion'of which piston `rod is coaxially disposed within said sleeve, said pist-on rod portion thereof having a threaded said piston land portions functioning to control linear motion of said seal contemporaneously with movement of said piston and rod member while said seal is maintained in a non-rotational relationship therewith while providing for rotational movement of the piston during controlled linear motion therewith, said piston land portions each having an annular concave frusto-conical configuration and being disposed in mutually juxtaposed relationship in a manner to matingly engage said seal;

whereby, as said piston and piston rod member is advanced through said barrel by Dotation of said lead screw portion of the piston rod, said seal is advanced therethrough in a non-rotatable manner, thereby providing a positive seal between said piston spool -portion and said barrel.

References Cited by the Examiner UNITED STATES PATENTS 938,544 11/1909 Ball 12S-218 1,232,076 7/1917 Pettit Z22-390 1,724,617 8/1929 Rapellin 222--390 2,607,342 8/1952 Abel 12S-218 ROBERT B. REEVES, Primary Examiner.

STANLEY H. TOLLBERG, Examiner.

Claims (1)

  1. 5. A MICROMETER CONTROLLED LEAK-PROOF SYRINGE COMPRISING: AN OUTER BARREL FORMED OF A TRANSPARENT MATERIAL; A SLEEVE SLIDABLY DISPOSED WITHIN SAID BARREL, SAID SLEEVE EXTENDING THROUGHOUT A SUBSTANTIAL PORTION OF THE AXIAL LENGTH OF SAID BARREL, SAID SLEEVE HAVING A TAPPED BORE AT ONE END THEREOF; MEANS RELEASABLY SECURING SAID SLEEVE TO SAID BARREL; A ROTATABLE PISTON ROD COAXIALLY DISPOSED WITHIN SAID BARREL AND THREADABLY ENGAGING THE TAPPED BORE OF SAID SLEEVE; A ROTATABLE PISTON SECURED TO SAID PISTON ROD AND COAXIALLY DISPOSED WITHIN SAID BARREL; ANNULAR SEAL MEANS DISPOSED ON SAID PISTON AND CONTACTING THE INSIDE SURFACE OF SAID BARREL; AND MEANS TO PREVENT ROTATION OF SAID SEAL ON SAID PISTON AS SAID PISTON IS ROTATED IN SAID BARREL.
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Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3884220A (en) * 1972-07-05 1975-05-20 Leo J Hartnett Method for injecting X-ray contrast media for venography of the female pelvis
US3961731A (en) * 1974-05-02 1976-06-08 Mochida Seiyaku Kabushiki Kaisha Dripping vessel
US4089335A (en) * 1976-11-11 1978-05-16 Harris Rano J Microsyringe
US4245654A (en) * 1977-03-22 1981-01-20 Concord Laboratories, Inc. Blood sampling syringe
US4267846A (en) * 1979-01-29 1981-05-19 Critikon, Inc. Controlled volume blood sampling syringe
US4664635A (en) * 1985-09-12 1987-05-12 Divetronic Ag Simulation device
US5314416A (en) * 1992-06-22 1994-05-24 Sherwood Medical Company Low friction syring assembly
US5456388A (en) * 1993-09-21 1995-10-10 Honstein; Jerry P. Thumbwheel operated metering dispenser for adhesives
US5843042A (en) * 1996-11-06 1998-12-01 Ren; Liang Chen Oral medicine dispensing device having a metered syringe component and reservoir
US6571992B2 (en) * 2001-01-12 2003-06-03 Dentsply Research & Development Corp. Dispensing syringe
US6793660B2 (en) 2001-08-20 2004-09-21 Synthes (U.S.A.) Threaded syringe for delivery of a bone substitute material
US20040204715A1 (en) * 2001-02-12 2004-10-14 Evans Avery J. Multi-use surgical cement dispenser apparatus and kit for same
WO2005030298A2 (en) * 2003-09-30 2005-04-07 Cardio, Inc. System for injecting liquid drug containing biological material
US20070140914A1 (en) * 2005-12-21 2007-06-21 Yoshiki Sawa Reagent-introducing medical device configured to create laminar flow and rotating flow
US20080132850A1 (en) * 2006-10-24 2008-06-05 Hideo Fumiyama Syringe With Rotatable Element, Infusion/Aspiration Systems Including the Syringe, and Associated Methods
US20100094307A1 (en) * 2001-02-12 2010-04-15 Evans Avery J Multi-use surgical cement dispenser apparatus and kit for same
US20100270335A1 (en) * 2009-04-24 2010-10-28 Agilent Technologies, Inc. Syringe with Improved Plunger
US20110313396A1 (en) * 2010-06-18 2011-12-22 Chanoch Lawrence H Adjustable dose setting plunger for syringe
USD690004S1 (en) 2012-03-16 2013-09-17 Aderans Research Institute, Inc. Holder for a device for delivering cellular material and physiologic fluids
US8939959B2 (en) 2008-01-30 2015-01-27 Becton, Dickinson And Company Dose dividing delivery device
US9060826B2 (en) 2009-04-03 2015-06-23 Ebi, Llc Method and apparatus for delivering bone cement
US9295509B2 (en) 2010-02-18 2016-03-29 Globus Medical, Inc. Methods and apparatus for treating vertebral fractures

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US938544A (en) * 1908-11-28 1909-11-02 William Ball Hypodermic syringe.
US1232076A (en) * 1912-02-07 1917-07-03 Edmund A Strause Lubricant-injector.
US1724617A (en) * 1927-10-01 1929-08-13 Rapellin Rene Grease gun
US2607342A (en) * 1950-11-24 1952-08-19 Martin S Abel Syringe

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US938544A (en) * 1908-11-28 1909-11-02 William Ball Hypodermic syringe.
US1232076A (en) * 1912-02-07 1917-07-03 Edmund A Strause Lubricant-injector.
US1724617A (en) * 1927-10-01 1929-08-13 Rapellin Rene Grease gun
US2607342A (en) * 1950-11-24 1952-08-19 Martin S Abel Syringe

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3884220A (en) * 1972-07-05 1975-05-20 Leo J Hartnett Method for injecting X-ray contrast media for venography of the female pelvis
US3961731A (en) * 1974-05-02 1976-06-08 Mochida Seiyaku Kabushiki Kaisha Dripping vessel
US4089335A (en) * 1976-11-11 1978-05-16 Harris Rano J Microsyringe
US4245654A (en) * 1977-03-22 1981-01-20 Concord Laboratories, Inc. Blood sampling syringe
US4267846A (en) * 1979-01-29 1981-05-19 Critikon, Inc. Controlled volume blood sampling syringe
US4664635A (en) * 1985-09-12 1987-05-12 Divetronic Ag Simulation device
US5314416A (en) * 1992-06-22 1994-05-24 Sherwood Medical Company Low friction syring assembly
US5456388A (en) * 1993-09-21 1995-10-10 Honstein; Jerry P. Thumbwheel operated metering dispenser for adhesives
US5843042A (en) * 1996-11-06 1998-12-01 Ren; Liang Chen Oral medicine dispensing device having a metered syringe component and reservoir
US6571992B2 (en) * 2001-01-12 2003-06-03 Dentsply Research & Development Corp. Dispensing syringe
US20100094307A1 (en) * 2001-02-12 2010-04-15 Evans Avery J Multi-use surgical cement dispenser apparatus and kit for same
US20040204715A1 (en) * 2001-02-12 2004-10-14 Evans Avery J. Multi-use surgical cement dispenser apparatus and kit for same
US7371241B2 (en) * 2001-02-12 2008-05-13 Modmed Therapeutics, Inc. Multi-use surgical cement dispenser apparatus and kit for same
US8506572B2 (en) 2001-02-12 2013-08-13 Carefusion 2200, Inc. Multi-use surgical cement dispenser apparatus and kit for same
US6793660B2 (en) 2001-08-20 2004-09-21 Synthes (U.S.A.) Threaded syringe for delivery of a bone substitute material
WO2005030298A3 (en) * 2003-09-30 2005-08-04 Asahi Intecc Co Ltd System for injecting liquid drug containing biological material
WO2005030298A2 (en) * 2003-09-30 2005-04-07 Cardio, Inc. System for injecting liquid drug containing biological material
US20070140914A1 (en) * 2005-12-21 2007-06-21 Yoshiki Sawa Reagent-introducing medical device configured to create laminar flow and rotating flow
US20080132850A1 (en) * 2006-10-24 2008-06-05 Hideo Fumiyama Syringe With Rotatable Element, Infusion/Aspiration Systems Including the Syringe, and Associated Methods
US8939959B2 (en) 2008-01-30 2015-01-27 Becton, Dickinson And Company Dose dividing delivery device
US9579465B2 (en) 2008-01-30 2017-02-28 Becton, Dickinson And Company Dose dividing delivery device
US9060826B2 (en) 2009-04-03 2015-06-23 Ebi, Llc Method and apparatus for delivering bone cement
US8322577B2 (en) 2009-04-24 2012-12-04 Agilent Technologies, Inc. Syringe with improved plunger
US20100270335A1 (en) * 2009-04-24 2010-10-28 Agilent Technologies, Inc. Syringe with Improved Plunger
US9295509B2 (en) 2010-02-18 2016-03-29 Globus Medical, Inc. Methods and apparatus for treating vertebral fractures
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