US3013557A - Combination syringe, shipping container and centrifuge tube - Google Patents

Combination syringe, shipping container and centrifuge tube Download PDF

Info

Publication number
US3013557A
US3013557A US80617159A US3013557A US 3013557 A US3013557 A US 3013557A US 80617159 A US80617159 A US 80617159A US 3013557 A US3013557 A US 3013557A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
cylinder
piston
end
rear
cap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Arthur J Pallotta
Original Assignee
Hazleton Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150503Single-ended needles
    • A61B5/150519Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/15058Joining techniques used for protective means
    • A61B5/150587Joining techniques used for protective means by friction fit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150694Procedure for removing protection means at the time of piercing
    • A61B5/150717Procedure for removing protection means at the time of piercing manually removed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150732Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150259Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150312Sterilisation of piercing elements, piercing devices or sampling devices

Description

UGE TUBE Dec. 19, 1961 A. J. PALLOTTA COMBINATION SYRINGEZ, SHIPPING CONTAINER AND CEN'I'RIF Filed April 13. 1959 INVENTOR ARTHUR ,J. PALLOTTA BY M M ATTORNEY8 United rates Fatent 3,013 557 (IQMEENATEGN SYRINGEZ SHTPPWG CONTAXNER AND CENTRTEUGE TUBE Arthur- J. Paillotta, Falis Church, Va, assignor to Hazleton Lahorat rites incorporated, Falls Church, Ja., a

corporation of Virginia lFiied Apr. 13, 1959, Ser. No. 8%,171 Claims. 31. 128-218) This invention is directed to an improved syringe construction adaptable as a shipping container and a centriafuge tube.

" An object of this invention is to provide a combined syringe which may be used to take a sample, may be sealed and shipped and later used as a centrifuge container.

Another object of the invention is to provide a syringe having a plastic cylinder of relatively flexible material with an open front end adapted to receive a cap for connection with a hypodermic needle and a tapered rear end apertured to receive a piston rod, there being received in the cylinder a piston of relative rigid material having a squeezing fit with the surrounding flexible wall of the cylinder and a tapered rear end for sealing fit in the tapered rear end of the cylinder.

A further object of the invention is to provide a combination syringe, shipping container and centrifuge tube that may be economically made of plastic material that is easily sterilized for use, scalable for shipping and usable as a centrifuge tube after which it may be thrown away.

A still further object of the invention is to provide a syringe type of container with a flexible wall which has an elastic contracting engagement with a relatively hard piston and wherein a piston rod receiving end has a tapered configuration to seal with a like shaped rear portion of the piston when drawn therein and the other end of the cylinder has a snap fitting engaging means with a cap having snap fitting engagement over the end of the cylinder and a hypodermic needle receiving apertured boss or nipple extending outward therefrom which after detachment of the hypodermic needle may receive a closure cap.

Other objects of this invention will, in part, be obvious and in part appear hereinafter.

This invention is disclosed in the embodiment thereof shown in the accompanying drawing and it comprises the features of construction, combination of elements and arrangement of parts that will be exemplified in the construction hereinafter set forth and the scope of the application of which will be indicated in the appended claims.

For a more complete understanding of the nature and scope of this invention reference can be had to the following detailed description, taken together with the accompanying drawing, in which:

FIG. 1 is a side elevation of this combination syringe;

FIG. 2 is a side elevation of the syringe in section at each end and on an enlarged scale;

FIG. 3 is a closure cap for the hypodermic needle receiving nipple of the syringe;

FIG. 4 is a view along line 4-4 of FIG. 2;

FIG. 5 is a view of a modified form of piston; and

FIG. 6 is a further modified form of piston with the piston rod upper portion broken off.

Throughout the description like reference numbers refer to similar parts.

A syringe according to the invention is generally indicated at 10. It comprises a body member 11 which is cylindrical throughout the greater extent and has a tapered rear end portion 12 decreasing in cross section toward the rear end aperture 13 thereof while the front ice end is open and has an outwardly extending flange 14 thereon. This body member or generally cylindrical member 11 is made of plastic material such as polyethylene as by injection molding or pressure molding. It is of such character that its walls are slightly yieldable and squeeze in against a piston 15 of relatively harder plastic material such as polyethylene or nylon. Other materials may be employed for the cylinder 11 and the piston so long as they are sterilizable and there is a squeezing cooperation between the walls and the piston to insure a suction making fit. The piston 15 has a rear portion 15' that is tapered in decreasing circular cross section about mid length of the piston to the rear end. This tapered piston portion 15 is of like taper to the rear tapered portion 12 of the body member 11 and when the piston 15 is pulled thereinto by the piston rod 16 attached thereto as a threaded end 16 received in a threaded end aperture 15" in the piston, a seal is formed at the rear end of the syringe 10. Piston rod 16 is of somewhat brittle material that may be broken off when a sample of blood, for example, has been drawn into the syringe. The piston rod 16 may be of certain selected hardness nylon or even glass. A knob or hand grasp portion 17 may be attached or integrally formed on the outer end of piston rod 16.

On the body member 11 conventional indicia volume indications such as 18 may be stamped or etched or formed therein.

Over the front open end and outwardly extending flange 14 of body member 11 is received a cap member 19 having a rearwardly extending shoulder 19' having an annular recess 19" therein that is received by a snap fit engagement over the flanged end 14 of member 11. Cap 19 has a central aperture and an apertured boss or nipple 20 extending from the front face so that the aperture therethrough is in alignment with the aperture in the cap 19. The nipple 20 has a tapered outer surface, decreasing in cross section from rear to front end and intermediate its length there is formed therein an annular groove 20'. This nipple or boss 20 receives thereon a hypodermic needle such as 22 so that the syringe may be used to take a blood sample or the like.

A cover cap or closure member 21 is provided to be received over the boss or nipple 20. The cover cap 21 is formed with an inwardly extending annular lip at its rear end and is tapered so as to be received tightly over the boss 20 after the hypodermic needle 22 has been removed. The lip 21' of the cover cap 21 is received in the annular groove 20 within which it tightly seats and grips.

In practice the hypodermic needle may be left in place on the boss 20 and sealed by binding or by embedding. However, if the needle is removed, the cover cap 21 may be installed over the boss 20.

In FIG. 5 a modified form of piston 23 is shown. It is formed with a pair of spaced apart lands 23a which have a diameter slightly in excess of the internal diameter of the cylindrical body portion 11 of the syringe so as to provide a fit which will provide a suction ahead of the piston 23. The rear end of piston 23 at 23b is tapered in a manner lilre tapered portion 15' of piston 15. The rear end of piston 23 has an apertured axially extending threaded recess therein such as 23c to receive the threaded end 16' of piston 16.

in FIG. 6 a further modification of the form a piston 24 may take is illustrated. Here a plurality of lands 24a, such as four, are provided which have a semi-circular shaped peripheral cross section. The rear tapered portion 24b serves as a seal with the surrounding tapered wall 12 of the syringe when such a piston as 24 is used. A piston rod in is likewise secured to the piston 24.

An example of a syringe might be one made according to this invention that has an overall length for member 11 of 3 /4 inches While the inside diameter is .60 of an inch. An example of the size of the cooperating piston 15 is one having a diameter of .60 of an inch. In FIG. the piston 23 may have a diameter of .595 inch while. in FIG. 6, for example, the piston 24 is made with the diam.- eter of the lands transverse to the axis of the piston as .6312 inch. These respective sizes of the elements have been found to provide a high suction and efficient syringe. An example of-the length of the piston is .50 inch with the tapered portion thereof having a degree included angle.

While the boss has been illustrated, for example, as extending about inch with an included taper angle of-4 degrees, a longer boss may be provided of more flexible material.

This syringe may be. used for most purposes for which a glass syringe is utilized. It is especially advantageous in the collection of blood for bacteriological, chemical, or other clinical studies. The syringe according to the invention is received as a sterile package ready for use. When the blood has been drawn, the unit can be shipped intact to the laboratory, and there the barrel of the Syringe can be used as a container and as a centrifuge tube. It is discarded along with the blood atthe completion of the study.

While the preferred type of combined syringe, shipping container and centrifuge tube has been disclosed as having the container of relatively flexible material and the piston of relatively hard material, it is within the scope of the invention to have the container of relatively hard material, suchas glass material, while the piston is of relatively flexible material as rubber or a suitable plastic composition.

The invention is. claimed as follows:

1. A.medical sampling and specimen container comprising, in combination, a cylinder of an elastic material having an outwardly extending flange at the front open end thereof and a gradually tapering rear end portion decreasing in cross section toward the rear open end; a. plunger having a' relatively rigid head slidable in snug fitting engagement within the. surrounding elastic wall of said cylinder and having substantially the rear half end thereof tapering to be received in a surrounding tapered portion of the cylinder when drawn therein and a plunger rod attached to said plunger head and extending through the rear open end of said cylinder, said plunger rod being of a relatively rigid yet breakable material permitting it to be broken off adjacent the rear end of the cylinder after the plunger head is drawn to the rear and secured in the rear tapered end of the cylinder; and a caphaving a rearwardly extending shoulder with an annular recess therein yieldably received in snap fitting engagement over said outwardly extending flange at the front end of the cylinder, said cap having a forwardly extending boss on the outer face thereof having an axially extending aperture therethrough in communication and alignment with an axially extending aperture through said cap, said boss being adapted to receive a hypodermic needle attachable thereto.

2. A medical sampling and specimen container according to claim 1 including incombination therewith a cover cap received .by and secured on said forwardly projecting boss on said cap of the cylinder.

3. A medical'sampling and specimen container according to claim 1 wherein said tapered rear end of the cylinder tapers down to the aperture thereof which has tight fitting but slidable engagement with said plunger rod.

4. A medical sampling and specimen container according to claim 1 wherein said boss on said cap for the cylinder has a gradual taper from rear end where it joins the cap to forward end and has an annular recess therein intermediate the rear and forward end thereof and a cap for said boss, said cap for the boss having a tapered inner surface and an inwardly extending annular lip at its rear open end, said cap for the boss being received over the boss in close fitting engagement and said inwardly extending lip received within the annular recess of the boss thereby securing the cap on the boss.

5. A medical sampling and specimen container comprising, in combination, a cylinder of an elastic material having an outwardly extending flange at the front open end thereof and a gradually tapering rear end portion decreasing in cross section toward the rear open end; a plunger having a relatively rigid head formed with a plurality of annular lands thereon of larger diameter than the inside diameter of the cylinder and slidably received in snug fitting engagement within the surrounding elastic wall of said cylinder when drawn therein whereby the cylinder wall has generally radially inward gripping engagement on said lands and a plunger rod attached to said plunger head and extending through the rear open end of said cylinder, said rear open end of the cylinder having a radially inwardly extending gripping engagement with said rod, said plunger rod being of a relatively hard yet breakable material permitting it to be broken off adjacent the rear end of the cylinder after the plunger head is drawn to the rear and secured in the rear tapered end of the cylinder; and a cap having a rearwardly extending shoulder with an annular recess therein yieldably received in snap fitting engagement over said outwardly extending flange at the front end of the cylinder, said cap having a forwardly extending boss on the outer face thereof having an axially extending aperture therethrough in communication and alignment with an axially extending aperture through said cap, said boss being adapted to receive a hypodermic needle attachable thereto.

6. A medical sampling and specimen container according to claim 5 wherein said boss on said cap for the cylinder has a gradual taper from rear end where it joins the cap to forward remote end and has an annular recess therein intermediate the rear and forward ends thereof and a cap for said boss when a needle is not attached thereto, said cap for the boss having a tapered inner surface and an inwardly extending annular lip at its rear open end, said cap for the boss being received over the boss in close fitting engagement and said inwardly extending lip received within the annular recess of the boss thereby securing the cap on the boss.

7. A medical sampling and specimen container according to claim 5 wherein the cylinder instead of being of elastic material is of relatively hard material and the plunger instead of being of a relatively rigid material is of a relatively flexible material.

8. A medical sampling and specimen container comprising, in combination, a cylinder having an outwardly extending flange at the front open end thereof and a gradually tapering rear end portion decreasing in cross section toward the rear open end; a plunger having a head slidable in snug fitting engagement within the surrounding wall of the cylinder and having substantially the rear half end thereof tapering to be received in a surrounding tapered portion of the cylinder when drawn therein and a plunger rod attached to said plunger head and extending through the rear open end of said cylinder, said plunger rod being of relatively rigid yet breakable material permitting it to be broken off adjacent the rear end of the cylinder after the plunger head is drawn to the rear and secured in the rear tapered end of the cylinder; and a cap having a rearwardly extending shoulder with an annular recess therein yieldably received in snap fitting engagement over said outwardly extending flange at the front end of the cylinder, said cap having a forwardly extending boss on the outer face thereof having an axially extending aperture therethrough in communication and alignment with an axially extending aperture through said c ceive a hypodermic needle 9. A medical sampli b said boss being adapted to reattachable thereto.

ng and specimen container comprising an elongated hollow member having an opening at positive engagement with said hollow member converging internal wall portion, and a rod member secured to said References Cited in the file of this patent UNITED STATES PATENTS

US3013557A 1959-04-13 1959-04-13 Combination syringe, shipping container and centrifuge tube Expired - Lifetime US3013557A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US3013557A US3013557A (en) 1959-04-13 1959-04-13 Combination syringe, shipping container and centrifuge tube

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3013557A US3013557A (en) 1959-04-13 1959-04-13 Combination syringe, shipping container and centrifuge tube

Publications (1)

Publication Number Publication Date
US3013557A true US3013557A (en) 1961-12-19

Family

ID=25193483

Family Applications (1)

Application Number Title Priority Date Filing Date
US3013557A Expired - Lifetime US3013557A (en) 1959-04-13 1959-04-13 Combination syringe, shipping container and centrifuge tube

Country Status (1)

Country Link
US (1) US3013557A (en)

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3181529A (en) * 1962-07-30 1965-05-04 Edgar H Wilburn Valved body-fluid sampling tubes
US3354882A (en) * 1964-10-26 1967-11-28 Pharmaseal Lab Hypodermic syringe
US3640268A (en) * 1965-10-23 1972-02-08 Hugh J Davis Method and device for biopsy specimen collecting and handling
US3753432A (en) * 1971-03-10 1973-08-21 L Guerra Hypodermic syringe for blood tests
US3785366A (en) * 1961-06-05 1974-01-15 H Davis Method and apparatus for disease diagnosis
US3937211A (en) * 1972-10-27 1976-02-10 Fa. Walter Sarstedt Kunststoff-Spritzgusswerk Multi-purpose syringe
US3962085A (en) * 1973-12-19 1976-06-08 Abbott Laboratories Skimmer assembly
US4129130A (en) * 1975-11-05 1978-12-12 Federico Bigarella Vial-syringe
FR2455450A1 (en) * 1979-05-03 1980-11-28 Transmed Corp A diagnostic samples taken
US4363329A (en) * 1978-01-17 1982-12-14 Concord Laboratories, Inc. Syringe having a reverse-taper barrel
US4562844A (en) * 1984-11-27 1986-01-07 Jett Labs, Inc. Multipurpose syringe
US4610171A (en) * 1985-04-26 1986-09-09 Nason Frederic L Urinanalysis vial
US4722352A (en) * 1983-11-15 1988-02-02 Walter Sarstedt Kunststoff-Spritzgusswerk Blood extraction device
US20080145933A1 (en) * 2006-12-18 2008-06-19 Patton Richard G Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US20090014391A1 (en) * 2002-05-03 2009-01-15 Biomet Biologics, Llc Buoy Suspension Fractionation System
US8048321B2 (en) 2002-05-24 2011-11-01 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8062534B2 (en) 2002-05-24 2011-11-22 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8119013B2 (en) 2007-04-12 2012-02-21 Hanuman, Llc Method of separating a selected component from a multiple component material
US8187477B2 (en) 2002-05-03 2012-05-29 Hanuman, Llc Methods and apparatus for isolating platelets from blood
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US8535241B2 (en) 2011-10-13 2013-09-17 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US8783470B2 (en) 2009-03-06 2014-07-22 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8808551B2 (en) 2002-05-24 2014-08-19 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8864684B2 (en) 2011-10-13 2014-10-21 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9022951B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9149576B2 (en) 2012-10-11 2015-10-06 Magnolia Medical Technologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination
US9155495B2 (en) 2012-11-30 2015-10-13 Magnolia Medical Technologies, Inc. Syringe-based fluid diversion mechanism for bodily fluid sampling
US9204864B2 (en) 2012-08-01 2015-12-08 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9556243B2 (en) 2013-03-15 2017-01-31 Biomet Biologies, LLC Methods for making cytokine compositions from tissues using non-centrifugal methods
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9701728B2 (en) 2008-02-27 2017-07-11 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
US9788774B2 (en) 2013-03-12 2017-10-17 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9897589B2 (en) 2002-05-24 2018-02-20 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9950084B2 (en) 2015-09-03 2018-04-24 Magnolia Medical Technologies, Inc. Apparatus and methods for maintaining sterility of a specimen container

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB189506022A (en) * 1895-03-22 1895-05-18 August Evens Improvements in Syringes or like Surgical Instruments.
US2549417A (en) * 1949-08-10 1951-04-17 Frederick M Turnbull Syringe ampoule
US2722257A (en) * 1953-02-12 1955-11-01 Compule Corp Sampling tube equipment
US2727514A (en) * 1952-09-13 1955-12-20 Compule Corp Aspirating hypodermic syringe and blood sampling devices
US2764978A (en) * 1953-11-13 1956-10-02 S & R J Everett & Co Ltd Locking device for hypodermic needles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB189506022A (en) * 1895-03-22 1895-05-18 August Evens Improvements in Syringes or like Surgical Instruments.
US2549417A (en) * 1949-08-10 1951-04-17 Frederick M Turnbull Syringe ampoule
US2727514A (en) * 1952-09-13 1955-12-20 Compule Corp Aspirating hypodermic syringe and blood sampling devices
US2722257A (en) * 1953-02-12 1955-11-01 Compule Corp Sampling tube equipment
US2764978A (en) * 1953-11-13 1956-10-02 S & R J Everett & Co Ltd Locking device for hypodermic needles

Cited By (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3785366A (en) * 1961-06-05 1974-01-15 H Davis Method and apparatus for disease diagnosis
US3181529A (en) * 1962-07-30 1965-05-04 Edgar H Wilburn Valved body-fluid sampling tubes
US3354882A (en) * 1964-10-26 1967-11-28 Pharmaseal Lab Hypodermic syringe
US3640268A (en) * 1965-10-23 1972-02-08 Hugh J Davis Method and device for biopsy specimen collecting and handling
US3753432A (en) * 1971-03-10 1973-08-21 L Guerra Hypodermic syringe for blood tests
US3937211A (en) * 1972-10-27 1976-02-10 Fa. Walter Sarstedt Kunststoff-Spritzgusswerk Multi-purpose syringe
US3962085A (en) * 1973-12-19 1976-06-08 Abbott Laboratories Skimmer assembly
US4129130A (en) * 1975-11-05 1978-12-12 Federico Bigarella Vial-syringe
US4363329A (en) * 1978-01-17 1982-12-14 Concord Laboratories, Inc. Syringe having a reverse-taper barrel
FR2455450A1 (en) * 1979-05-03 1980-11-28 Transmed Corp A diagnostic samples taken
US4320770A (en) * 1979-05-03 1982-03-23 Trans-Med Corporation Diagnostic specimen collector
US4722352A (en) * 1983-11-15 1988-02-02 Walter Sarstedt Kunststoff-Spritzgusswerk Blood extraction device
US4562844A (en) * 1984-11-27 1986-01-07 Jett Labs, Inc. Multipurpose syringe
US4610171A (en) * 1985-04-26 1986-09-09 Nason Frederic L Urinanalysis vial
US8950586B2 (en) 2002-05-03 2015-02-10 Hanuman Llc Methods and apparatus for isolating platelets from blood
US20090014391A1 (en) * 2002-05-03 2009-01-15 Biomet Biologics, Llc Buoy Suspension Fractionation System
US7992725B2 (en) 2002-05-03 2011-08-09 Biomet Biologics, Llc Buoy suspension fractionation system
US8187477B2 (en) 2002-05-03 2012-05-29 Hanuman, Llc Methods and apparatus for isolating platelets from blood
US9897589B2 (en) 2002-05-24 2018-02-20 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8062534B2 (en) 2002-05-24 2011-11-22 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8163184B2 (en) 2002-05-24 2012-04-24 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8048321B2 (en) 2002-05-24 2011-11-01 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8603346B2 (en) 2002-05-24 2013-12-10 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9114334B2 (en) 2002-05-24 2015-08-25 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8808551B2 (en) 2002-05-24 2014-08-19 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8567609B2 (en) 2006-05-25 2013-10-29 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US10028689B2 (en) 2006-12-18 2018-07-24 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8337418B2 (en) 2006-12-18 2012-12-25 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US9855001B2 (en) 2006-12-18 2018-01-02 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8231546B2 (en) 2006-12-18 2012-07-31 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US9861306B2 (en) 2006-12-18 2018-01-09 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US9872645B2 (en) 2006-12-18 2018-01-23 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10052053B2 (en) 2006-12-18 2018-08-21 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8197420B2 (en) 2006-12-18 2012-06-12 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8647286B2 (en) 2006-12-18 2014-02-11 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10028687B2 (en) 2006-12-18 2018-07-24 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US9855002B2 (en) 2006-12-18 2018-01-02 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10045724B2 (en) 2006-12-18 2018-08-14 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US10028688B2 (en) 2006-12-18 2018-07-24 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8876734B2 (en) 2006-12-18 2014-11-04 Magnolia Medical Technologies, Inc. Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US20080145933A1 (en) * 2006-12-18 2008-06-19 Patton Richard G Systems and methods for parenterally procuring bodily-fluid samples with reduced contamination
US8119013B2 (en) 2007-04-12 2012-02-21 Hanuman, Llc Method of separating a selected component from a multiple component material
US8596470B2 (en) 2007-04-12 2013-12-03 Hanuman, Llc Buoy fractionation system
US9649579B2 (en) 2007-04-12 2017-05-16 Hanuman Llc Buoy suspension fractionation system
US8328024B2 (en) 2007-04-12 2012-12-11 Hanuman, Llc Buoy suspension fractionation system
US9138664B2 (en) 2007-04-12 2015-09-22 Biomet Biologics, Llc Buoy fractionation system
US9701728B2 (en) 2008-02-27 2017-07-11 Biomet Biologics, Llc Methods and compositions for delivering interleukin-1 receptor antagonist
US8801586B2 (en) * 2008-02-29 2014-08-12 Biomet Biologics, Llc System and process for separating a material
US20130196425A1 (en) * 2008-02-29 2013-08-01 Biomet Biologics, Llc System and Process for Separating a Material
US8337711B2 (en) 2008-02-29 2012-12-25 Biomet Biologics, Llc System and process for separating a material
US9719063B2 (en) 2008-02-29 2017-08-01 Biomet Biologics, Llc System and process for separating a material
US8783470B2 (en) 2009-03-06 2014-07-22 Biomet Biologics, Llc Method and apparatus for producing autologous thrombin
US8313954B2 (en) 2009-04-03 2012-11-20 Biomet Biologics, Llc All-in-one means of separating blood components
US8992862B2 (en) 2009-04-03 2015-03-31 Biomet Biologics, Llc All-in-one means of separating blood components
US9011800B2 (en) 2009-07-16 2015-04-21 Biomet Biologics, Llc Method and apparatus for separating biological materials
US9533090B2 (en) 2010-04-12 2017-01-03 Biomet Biologics, Llc Method and apparatus for separating a material
US8591391B2 (en) 2010-04-12 2013-11-26 Biomet Biologics, Llc Method and apparatus for separating a material
US9239276B2 (en) 2011-04-19 2016-01-19 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US8535241B2 (en) 2011-10-13 2013-09-17 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US10039483B2 (en) 2011-10-13 2018-08-07 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US8864684B2 (en) 2011-10-13 2014-10-21 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060725B2 (en) 2011-10-13 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9022951B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en) 2012-05-30 2015-06-23 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9022950B2 (en) 2012-05-30 2015-05-05 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9204864B2 (en) 2012-08-01 2015-12-08 Magnolia Medical Technologies, Inc. Fluid diversion mechanism for bodily-fluid sampling
US9642956B2 (en) 2012-08-27 2017-05-09 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
US9931466B2 (en) 2012-10-11 2018-04-03 Magnolia Medical Tehnologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination
US9149576B2 (en) 2012-10-11 2015-10-06 Magnolia Medical Technologies, Inc. Systems and methods for delivering a fluid to a patient with reduced contamination
US9155495B2 (en) 2012-11-30 2015-10-13 Magnolia Medical Technologies, Inc. Syringe-based fluid diversion mechanism for bodily fluid sampling
US9999383B2 (en) 2012-11-30 2018-06-19 Magnolia Medical Technologies, Inc. Syringe-based fluid diversion mechanism for bodily fluid sampling
US9788775B2 (en) 2013-03-12 2017-10-17 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US9788774B2 (en) 2013-03-12 2017-10-17 Magnolia Medical Technologies, Inc. Methods and apparatus for selectively occluding the lumen of a needle
US9556243B2 (en) 2013-03-15 2017-01-31 Biomet Biologies, LLC Methods for making cytokine compositions from tissues using non-centrifugal methods
US9895418B2 (en) 2013-03-15 2018-02-20 Biomet Biologics, Llc Treatment of peripheral vascular disease using protein solutions
US9950035B2 (en) 2013-03-15 2018-04-24 Biomet Biologics, Llc Methods and non-immunogenic compositions for treating inflammatory disorders
US9950084B2 (en) 2015-09-03 2018-04-24 Magnolia Medical Technologies, Inc. Apparatus and methods for maintaining sterility of a specimen container

Similar Documents

Publication Publication Date Title
US3477432A (en) Combination mixing and injecting medical syringe
US3525264A (en) Micropipette holder
US3364930A (en) Sterile venoclysis apparatus and recipient set for use therwith
US3390759A (en) Shield and hub for disposable needle
US3556099A (en) Hypodermic syringe assembly
US4135513A (en) Drinking nozzle for bottles and similar containers
US5078698A (en) Axial eject hypodermic syringe holder
US4619651A (en) Anti-aerosoling drug reconstitution device
US4240425A (en) Syringe with plug type needle hub lock
US6413237B1 (en) Hypodermic syringe with selectively retractable needle
US6096005A (en) Retractable needle medical devices
US5772652A (en) Stab cap for a vial having a puncturable seal
US3729031A (en) Liquid dispenser and plunger and method and apparatus for filling same
US4755169A (en) Automatic medicament ingredient mixing and injecting apparatus
US5637101A (en) Quick release needle coupling system
US4036232A (en) Aspiration device
US5163583A (en) Aspiration cap for dispensing blood or other fluids for diagnostic purposes
US6361744B1 (en) Self-resealing closure for containers
US5181909A (en) Ampule-container medical syringe and methods
US4320769A (en) Universal holder for blood collecting tubes
US4243080A (en) Method of mixing plural components
US3680558A (en) Syringe with multiple compartments
US6312413B1 (en) Cylinder ampoule
US4803998A (en) Swab retaining vial cap and method of use
US5064419A (en) Disposable hypodermic syringe