US2893395A - Medical assembly and unit for liquid transfer - Google Patents

Medical assembly and unit for liquid transfer Download PDF

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Publication number
US2893395A
US2893395A US63913557A US2893395A US 2893395 A US2893395 A US 2893395A US 63913557 A US63913557 A US 63913557A US 2893395 A US2893395 A US 2893395A
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Prior art keywords
assembly
cannula
parts
unit
catheter
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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James R Buck
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Becton Dickinson and Co
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Becton Dickinson and Co
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/0215Measuring pressure in heart or blood vessels by means inserted into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221Valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150236Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150244Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150992Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10Tube connectors; Tube couplings

Description

July 7, 1959 J, R ug 2,893,395

MEDICAL ASSEMBLY AND UNIT FOR LIQUID TRANSFER Filed Feb. 8, 1957 INVENTOR JZlmes if. Back v BY m dmwtw ATTORNEYS MEDICAL ASSEMBLY AND UNIT FOR LIQUID TRANSFER James-R. Buck, Jersey City, N.J., assignor to Becton, Dickinson and Company, Rutherford, N.J., a corporation of New Jersey Application February 8, 1957, Serial No. 639,135 8 Claims. (Cl. 128349) This invention relates to a structurally and functionally improved medical assembly and unit.

In its more specific aspects the invention provides a. structure whereby a catheter or tubing may be manipulated in accordance with the desires of the attending or operating physician so that the operation, or treatment being performed may proceed with maximum expediency and minimum danger to the patient. The assembly provided, will for example be of primary utility in the case of cardiac catheterization. I

As is well understood, by the medical profession, in such use considerable difficulty has ben experienced in inserting the catheter in the vein through to the heart, where rotation of the parts was necessary. More particularly, that rotation frequently causes curling of the nylon catheter, and occasionally it was found that the base or proximal-end of the instrument would crack 'due to the torsion strains which were present. In order to relieve these, the technique has been followed of looseningthe proximal end from the injection device and rotatin'g it. In such loosening, air may accidentally be permitted to enter through the bore of the catheter. Under these circumstances the continuous flow of anticoagulant fluid would be disrupted and the patient would be endangered.

By means of the present teachings, rotation of the catheter or other tubing is readily feasible without it being necessary to loosen or disconnect theproximal end of the same from the injection device.

A further object is that of furnishing a relatively simple structure which may be economically produced and which in use will not require the employment of any special technique or skill. Moreover, when included in an assembly, the unit may be frequently used, will be capable of ready and complete cleaning and sterilization and will function over long periods of time with freedom from all difiiculties.

7 With these and other objects in mind, reference is had to the attached sheet of drawing illustrating one practical embodiment of the invention, and in which:

Fig. 1 illustrates an assembly connected to a patient;

Fig. 2 is an enlarged sectional side view taken along the line 2-2 in the direction of the arrows as indicated inFig. 1; and,

- Fig.3 is a fragmentary side elevation of certain of the parts as included in Fig. 1.

Referring primarily to Fig. 1, the numeral 5 indicates a cannula in the form of a catheter having a free end provided with an outlet opening 6. In a preferred grouping ofapparatus embracing the present teachings, a tube 7 will be furnished connected to a container embracing, for example, a supply of anticoagulant liquid. A second tube 8 may be connected to an oscilloscope to record blood pressure and heart action. Neither the latter instrument nor the container connected to tube 7 have been illustrated. It is also preferred that there be included in the grouping a provision for taking a blood specimen. This may include a syringe assembly as genatent C ice 2 erally indicated at 9. If desired, a casing 10 housing a suitable needle valve structure may be interposed in tube 8 or the parts associated therewith.

A fitting assembly conveniently includes two three-way valves disposed within casings '11 and 12. From these casings, coupling units 13 extend to connect respectively with the syringe assembly 9 and the inner end of tube 8. Further couplings such as 14, 15 and 16 are preferably provided. These may be of the Luer, or any other proper type to provide a quick-detachable connection. These couplings may be separate elements or integral with parts of casings 11 or 12. In this manner, connections are provided which permit of a ready coupling and separation of the parts for cleaning, sterilization and storing. Similarly, an adapter generally designated under the numeral 17 may, by means of the coupling 16, be connected with casing 11 and by means of a coupling 13 be connected with the hub portion 19 of the cannula 5.

That adapter should permit of a ready swivellin-g action of the cannula with respect to the fitting assembly. At the same time however, there should be no danger of its parts permitting an entry of air into the lumen of the cannula. A preferred structure achieving this result has been illustrated in Fig. 2. As will be seen in that figure, and especially its right hand portion, the numeral 16 designates the generally cylindrical part of the coupling. Conveniently the outer edge of the same may be defined by radially extending ears of projections 20 while its forward end is continued in a non-cylindrical portion 21. This constitutes one part of a more or less conventional Luer coupling.

The second part of the same as shown in the left hand portion of Fig. 2. may include a collar 22 to receive the outer end of a coupling portion such as 16. The inner face of collar '22 is conventionally formed with screw threads (not shown) which are engageable by the projecting ears 20 of a coupling. Also inaccordance with accepted construction, there may be formed adjacent the base of collar 22, slots 23; the collar being concentrically disposed with respect to and spaced from the outer face of a tip (not shown). While this type of coupling is definitely preferred, it will be understood that any acceptable form of connection may be employed between the adapter and its adjacent parts as well as othenwise within the assembly. That coupling, however, should permit of ready access for purposes of cleaning and sterilization.

Fixed with respect to portion 21 is a plug 24. The latter has secured to it a collar 25, which extends forwardly of it and terminates in an inwardly extending flange portion 26. A hub 27 is also fixedly secured to collar 22 and similarly mounts a cup shaped member 28 which extends within the space defined by collar 25 and has a diameter greater than that defined by the inner end of flange part 26. A projection 29 is conveniently integral with plug 24, and extends into cup member 28 to a point immediately adjacent its face. A ring 30 of packing material is interposed between the side wall of cup member 28 and the projecting portion 29. That material may conveniently be natural or synthetic rubber. The several parts of the adapter are formed with aligned passages providing in aggregate an axially extending bore 31.

As shown in Fig. 2, a slightly exaggerated spacing of the parts has been resorted to. In actual practice, the threads which are conveniently provided between plug 24 and collar 25 permit of the latter being telescoped or drawn over that plug to a greater extent. So shifted, packing 30 will be slightly compressed between the base of cup member 28, the inner face of its side wall, the outer face of projecting portion 29 and the adjacent face of the plug. Under that compression, the ring will therefore establish an effective liquid-tight seal preventing any escape of the fluid within bore 31 to a point beyond the side face of the adapter, or air from flowing inwardly into bore 31. At the same time, the user of the apparatus will have no difficulty in gripping the outer face of hub 27, and rotating it together with member 28 to turn these parts around the axis as defined by projection 29. With a cannula secured against movement with respect to hub 27, that instrument will be similarly turned.

So shifted, it is obvious that the outlet end of the cannula lumen as indicated at 6 will be similarly rotated. Under certain circumstances it may be desired to provide an indication of the amount of rotation. To achieve this result, and as shown in Fig. 3, hub 27 may provide on its outer face graduation marks 32. A pointer, such as an extension 33 of collar 25 will register with these marks. A registration mark 34 may also be associated with the hub 19 of the cannula. That mark is conveniently aligned with the exit end of the lumen as well as, for example, with the central mark of the indicia 32.

Therefore, with the rotation of hub 27, the physician will be aware of the direction in which that exit end extends.

As will be understood, an assembly such as the present, is of inestimable value in the case of cardiac catheterization. Prior to the development of the assembly, there has been considerable dilficulty in inserting the catheter in the vein through to the heart. This is because rotation of the parts resulted in a curling of the catheter which is usually formed of nylon or similar material. Also, it was found that occasionally the proximal end of the cannula would crack due to torsion on the later. Heretofore to alleviate this strain, the proximal end of the catheter was ordinarily loosened from the injection device and rotated. Under these circumstances, there was great danger that air might enter the lumen of the cannula and thus disrupt the continuous flow of anticoagulant liquid.

With the present apparatus, an incision is made in the vein in the arm, and a catheter conveniently formed of "woven nylon is inserted. In that insertion, it is attached as shown in Fig. 1 preferably to two three-way valves such as 11 and 12, and through the former to a syringe assembly such as 9. The second coupling of valve 12 connects with a tube 7 coupled to a container having a solution of anticoagulant fluid. The second connection of this valve casing is coupled to tube 8 in turn connected to an oscilloscope or similar instrument. Where a needle valve such as is indicated at 10 is employed within this part of the assembly, any surges in blood pressure are reduced. This permits, in a more correct manner, the visualization of pressure on the oscilloscope.

With the catheter inserted in the vein, it is moved by rotation and proper manipulation towards the heart which it enters through the right auricle. Usually during this procedure, and throughout the entire operation, a small amount of anticoagulant solution is constantly flowing through the catheter. Where desirable, the flow may be interrupted by shifting the valve within casing 11. Thereupon the syringe assembly 9 will permit of the taking of specimens of blood from the heart for analysis. By a suitable manipulation of the valves within both casings 11 and 12, blood pressure may also be observed. Where a register or indication such as 3233 is resorted to, a physician will be able to determine precisely the extent to which rotation of the parts has been efiected. In other words, it is feasible to determine precisely the direction in which the discharge of the solution from opening 6 is occurring. Similarly, if a hollow needle, or other form of a cannula were involved, an equally accurate determination could be made.

While cardiac catheterization is a primary purpose of the present assembly and unit, it will be apparent that it might be advantageously otherwise utilized. For example, it may be employed by a urologist or gynecologist for the introduction of solutions into body cavities. A radiologist or surgeon may employ the assembly including the unit in the preparation of cardiograms. It may also be utilized in connection with spinal or caudal analgesia. In all instances, and without manipulating the entire assembly, the physician can readily rotate the catheter, tubing or other cannulae units with respect to the parts to which it is attached.

Thus, among others, the several objects of the invention as specifically aforenoted are achieved. Obviously numerous changes in construction and rearrangement of the parts may be resorted to without departing from the spirit of the invention as defined by the claims which are:

1. In a medical assembly in combination a cannula, a fluid-conducting tube to be connected to a source of liquid injectable through the cannula, a fitting assembly connected to said tube, coupling means associated with said assembly and cannula, connected and relatively rotatable parts providing an adapter, coupling means included in said adapter and engaged with the coupling means of said cannula and fitting respectively to furnish quickdetachable connections therewith and means accessible from the exterior of said adapter for causing relative rotation of its parts to turn said cannula around its axis and with respect to said fitting assembly.

2. In an assembly as defined in claim 1, and a syringe structure connected to said fitting assembly.

3. In a medical assembly as defined in claim 1, and a further fluid-conducting tube for ascertaining blood pressure conditions also connected to said fitting assembly.

4. In an assembly as defined in claim 3, and valve means connected to said latter tube for preventing pressure-surges therethrough.

5. In an assembly as defined in claim 1, said fitting assembly including a valve for controlling fluid flow from said tube.

6. In an assembly as defined in claim 1, a syringe, said fitting assembly including a pair of multiple type valves, one interposed between said cannula and tube, and the other between said syringe and cannula.

7. In an assembly as defined in claim 1, said cannula having its lumen terminate in an outlet opening, and indicating means associated with said cannula to indicate the disposition of such outlet with respect to one of the parts of said adapter.

8. In an assembly as defined in claim 1, and a fluidtight packing interposed between the surfaces of the relatively rotatable parts providing such adapter.

References Cited in the file of this patent UNITED STATES PATENTS 993,774 Greenlaw May 30, 1911 1,273,174 Noakes July 23, 1918 2,226,039 Wiltse Dec. 24, 1940 2,532,669 Jones Dec. 5, 1950 FOREIGN PATENTS 727,959 Great Britain Apr. 13, 1955

US2893395A 1957-02-08 1957-02-08 Medical assembly and unit for liquid transfer Expired - Lifetime US2893395A (en)

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Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352303A (en) * 1965-07-28 1967-11-14 Lawrence J Delaney Method for blood clot lysis
US3385300A (en) * 1965-08-10 1968-05-28 Holter Company Cervical cannula
US3416531A (en) * 1964-01-02 1968-12-17 Edwards Miles Lowell Catheter
US3452740A (en) * 1966-05-31 1969-07-01 Us Catheter & Instr Corp Spring guide manipulator
US3503385A (en) * 1965-09-27 1970-03-31 Cordis Corp Guidable catheter assembly and manipulator therefor
US3785683A (en) * 1971-02-01 1974-01-15 Siemens Ag Connecting device for a catheter
US3854477A (en) * 1973-04-06 1974-12-17 S Smith Apparatus and method for the application of a continuous somatic nerve block
US3918450A (en) * 1974-11-22 1975-11-11 Kendall & Co Catheter adapter
US3991762A (en) * 1974-09-30 1976-11-16 Radford F Richard Aspirating device for patient ventilation apparatus
FR2437841A2 (en) * 1978-06-05 1980-04-30 Applic Technologiques Et Blood vessel inspection catheter - with inflatable bulbs on coaxial channels and bonded washers for sealing
US4254773A (en) * 1978-11-24 1981-03-10 Medex Inc. Swivel coupling for a catheterization system
FR2535826A1 (en) * 1982-11-04 1984-05-11 Norton Co rotary connection, in particular for casings has associated catheters
EP0269768A1 (en) * 1986-12-01 1988-06-08 TEEPLE, Edward Anti-air embolism and antiblood loss device for CVPcatheter
EP0301913A2 (en) * 1987-07-31 1989-02-01 Lawrence A. Lynn Blood aspiration assembly
US4803999A (en) * 1981-11-16 1989-02-14 Liegner Kenneth B Catheter system
US4967743A (en) * 1987-03-11 1990-11-06 Ballard Medical Products Neonatal closed system for involuntary aspiration and ventilation, and method
US5065754A (en) * 1990-06-06 1991-11-19 Ballard Medical Products Aspirating catheter tube inserter
US5107829A (en) * 1987-03-11 1992-04-28 Ballard Medical Products Neonatal closed system for involuntary aspiration and ventilation, and method
US5133345A (en) * 1987-03-11 1992-07-28 Ballard Medical Products Neonatal closed system for involuntary aspiration and ventilation, and method
US5215522A (en) * 1984-07-23 1993-06-01 Ballard Medical Products Single use medical aspirating device and method
US5277177A (en) * 1984-07-23 1994-01-11 Ballard Medical Products Single use medical aspirating device and method
US5334160A (en) * 1992-05-04 1994-08-02 Scimed Life Systems, Inc. Intravascular catheter with sleeve and method for use thereof
US5509911A (en) * 1992-11-27 1996-04-23 Maxxim Medical, Inc. Rotating adapter for a catheterization system
US5527299A (en) * 1994-05-13 1996-06-18 Critical Disposables, Inc. One-piece rotator and manifold system
US5549583A (en) * 1995-08-04 1996-08-27 Adam Spence Corporation Surgical connector
US5694922A (en) * 1994-05-18 1997-12-09 Ballard Medical Products Swivel tube connections with hermetic seals
US5855568A (en) * 1996-11-22 1999-01-05 Liebel-Flarsheim Company Angiographic syringe and luer connector
US6494203B1 (en) 1994-08-19 2002-12-17 Ballard Medical Products Medical aspirating/ventilating closed system improvements and methods
EP1277486A2 (en) * 2001-06-05 2003-01-22 ARIES S.r.l. Disposable preassembled device particularly for photodynamic therapy
US20050137500A1 (en) * 2003-12-23 2005-06-23 Vance Products Incorporated D/B/A Cook Urological Incorporated Rotatable sampling apparatus
US20070142786A1 (en) * 2005-12-16 2007-06-21 Lampropoulos Fred P System with color-coded medical syringes and basins
US20080077063A1 (en) * 2006-09-21 2008-03-27 Tyco Healthcare Group Lp Safety Connector Apparatus
US20090001008A1 (en) * 2006-01-31 2009-01-01 Nandu Deorkar End-Cap Device For High Efficiency Disposable Chromatography Column
US20100012565A1 (en) * 2006-01-31 2010-01-21 Mallinckrodt Baker, Inc. High Efficiency Chromatography Column with Re-usable End Cap
US8257287B2 (en) 2008-03-20 2012-09-04 Tyco Healthcare Group Lp Safety connector assembly
US20140276596A1 (en) * 2010-11-01 2014-09-18 Biomet Manufacturing, Llc Cannulated syringe

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US993774A (en) * 1910-03-19 1911-05-30 Greenlaw Mfg Co Rotary pipe-joint.
US1273174A (en) * 1917-12-13 1918-07-23 George James Sheppard Pipe-coupling.
US2226039A (en) * 1940-04-22 1940-12-24 Arthur S Allen Fluid line connection
US2532669A (en) * 1947-05-19 1950-12-05 Oil Ct Tool Co Balanced thrust swivel joint
GB727959A (en) * 1953-12-31 1955-04-13 Drug Houses Of Australia Ltd Oesophageal tube for use with animal drench guns

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US993774A (en) * 1910-03-19 1911-05-30 Greenlaw Mfg Co Rotary pipe-joint.
US1273174A (en) * 1917-12-13 1918-07-23 George James Sheppard Pipe-coupling.
US2226039A (en) * 1940-04-22 1940-12-24 Arthur S Allen Fluid line connection
US2532669A (en) * 1947-05-19 1950-12-05 Oil Ct Tool Co Balanced thrust swivel joint
GB727959A (en) * 1953-12-31 1955-04-13 Drug Houses Of Australia Ltd Oesophageal tube for use with animal drench guns

Cited By (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3416531A (en) * 1964-01-02 1968-12-17 Edwards Miles Lowell Catheter
US3352303A (en) * 1965-07-28 1967-11-14 Lawrence J Delaney Method for blood clot lysis
US3385300A (en) * 1965-08-10 1968-05-28 Holter Company Cervical cannula
US3503385A (en) * 1965-09-27 1970-03-31 Cordis Corp Guidable catheter assembly and manipulator therefor
US3452740A (en) * 1966-05-31 1969-07-01 Us Catheter & Instr Corp Spring guide manipulator
US3785683A (en) * 1971-02-01 1974-01-15 Siemens Ag Connecting device for a catheter
US3854477A (en) * 1973-04-06 1974-12-17 S Smith Apparatus and method for the application of a continuous somatic nerve block
US3991762A (en) * 1974-09-30 1976-11-16 Radford F Richard Aspirating device for patient ventilation apparatus
US3918450A (en) * 1974-11-22 1975-11-11 Kendall & Co Catheter adapter
FR2437841A2 (en) * 1978-06-05 1980-04-30 Applic Technologiques Et Blood vessel inspection catheter - with inflatable bulbs on coaxial channels and bonded washers for sealing
US4254773A (en) * 1978-11-24 1981-03-10 Medex Inc. Swivel coupling for a catheterization system
US4803999A (en) * 1981-11-16 1989-02-14 Liegner Kenneth B Catheter system
FR2535826A1 (en) * 1982-11-04 1984-05-11 Norton Co rotary connection, in particular for casings has associated catheters
US5215522A (en) * 1984-07-23 1993-06-01 Ballard Medical Products Single use medical aspirating device and method
US5277177A (en) * 1984-07-23 1994-01-11 Ballard Medical Products Single use medical aspirating device and method
US5611336A (en) * 1984-07-23 1997-03-18 Ballard Medical Products, Inc. Single use medical aspirating device and method
EP0269768A1 (en) * 1986-12-01 1988-06-08 TEEPLE, Edward Anti-air embolism and antiblood loss device for CVPcatheter
US5107829A (en) * 1987-03-11 1992-04-28 Ballard Medical Products Neonatal closed system for involuntary aspiration and ventilation, and method
US5133345A (en) * 1987-03-11 1992-07-28 Ballard Medical Products Neonatal closed system for involuntary aspiration and ventilation, and method
US4967743A (en) * 1987-03-11 1990-11-06 Ballard Medical Products Neonatal closed system for involuntary aspiration and ventilation, and method
EP0301913A3 (en) * 1987-07-31 1989-03-15 Lawrence A. Lynn Blood aspiration and method
EP0301913A2 (en) * 1987-07-31 1989-02-01 Lawrence A. Lynn Blood aspiration assembly
US5065754A (en) * 1990-06-06 1991-11-19 Ballard Medical Products Aspirating catheter tube inserter
US5334160A (en) * 1992-05-04 1994-08-02 Scimed Life Systems, Inc. Intravascular catheter with sleeve and method for use thereof
US5509911A (en) * 1992-11-27 1996-04-23 Maxxim Medical, Inc. Rotating adapter for a catheterization system
US5527299A (en) * 1994-05-13 1996-06-18 Critical Disposables, Inc. One-piece rotator and manifold system
US5694922A (en) * 1994-05-18 1997-12-09 Ballard Medical Products Swivel tube connections with hermetic seals
US6494203B1 (en) 1994-08-19 2002-12-17 Ballard Medical Products Medical aspirating/ventilating closed system improvements and methods
US5549583A (en) * 1995-08-04 1996-08-27 Adam Spence Corporation Surgical connector
US5855568A (en) * 1996-11-22 1999-01-05 Liebel-Flarsheim Company Angiographic syringe and luer connector
EP1277486A2 (en) * 2001-06-05 2003-01-22 ARIES S.r.l. Disposable preassembled device particularly for photodynamic therapy
EP1277486A3 (en) * 2001-06-05 2004-06-09 ARIES S.r.l. Disposable preassembled device particularly for photodynamic therapy
US20050137500A1 (en) * 2003-12-23 2005-06-23 Vance Products Incorporated D/B/A Cook Urological Incorporated Rotatable sampling apparatus
US7641620B2 (en) * 2003-12-23 2010-01-05 Vance Products Incorporated Rotatable sampling apparatus
US20070142786A1 (en) * 2005-12-16 2007-06-21 Lampropoulos Fred P System with color-coded medical syringes and basins
US20090001008A1 (en) * 2006-01-31 2009-01-01 Nandu Deorkar End-Cap Device For High Efficiency Disposable Chromatography Column
US20100012565A1 (en) * 2006-01-31 2010-01-21 Mallinckrodt Baker, Inc. High Efficiency Chromatography Column with Re-usable End Cap
US9687249B2 (en) 2006-09-21 2017-06-27 Covidien Lp Safety connector assembly
US8257286B2 (en) 2006-09-21 2012-09-04 Tyco Healthcare Group Lp Safety connector apparatus
US8287517B2 (en) 2006-09-21 2012-10-16 Tyco Healtcare Group Lp Safety connector assembly
US20080077063A1 (en) * 2006-09-21 2008-03-27 Tyco Healthcare Group Lp Safety Connector Apparatus
US8257287B2 (en) 2008-03-20 2012-09-04 Tyco Healthcare Group Lp Safety connector assembly
US20140276596A1 (en) * 2010-11-01 2014-09-18 Biomet Manufacturing, Llc Cannulated syringe

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