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Hypodermic syringe

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US2735427A
US2735427A US2735427DA US2735427A US 2735427 A US2735427 A US 2735427A US 2735427D A US2735427D A US 2735427DA US 2735427 A US2735427 A US 2735427A
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syringe
barrel
plunger
sterilizing
carried
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/001Apparatus specially adapted for cleaning or sterilising syringes or needles

Description

Feb. 21, 1956 J. J. SULLIVAN HYPODERMIC SYRINGE Filed April 25, 1953 INVENTOR. C/OH/V J SULL/VAN @amv 4 f7, (Bean l 'A TTOPA/mis.

United States Patent O HYPDERMIC SYRENGE John J. Sullivan, Bulfalo, N. Y.

Application April 23, 1953, Serial No. 350,691

9 Claims. (Cl. 12S-21S) My invention relates in general to hypodermic syringes, and in particular to an attachment for a hypodermic syringe.

The principal object of my invention is to provide an attachment for use with a hypodermic syringe which makes it possible for the operator to manipulate the syringe with one hand only, thereby avoiding wobbling of the needle, which is painful to the patient.

Another vobject is to provide an attachment which may'be used with any standard syringel Another object is to provide means whereby a hypodermic syringe may be successfully used by a patient in the self-administration of a hypodermic injection.

A'further object is to provide means whereby the leakage of medicine from a filled hypodermic syringe may be avoided, and whereby the syringe may be placed upon a supporting surface in a vertical position, thereby preventing the needle from becoming contaminated by touching the surface.

Moreover, my invention is such that a hypodermic injection may be conveniently given in any desired position.

Moreover, my invention permits the use of a hypodermic syringe at places where means of sterilization are not available.

Furthermore, my invention avoids the spilling and wasting of expensive serums.

The above objects and advantages have been accomplished by the device shown in the accompanying drawings, of which:

Fig. 1 is a side sectional elevation of my device as applied to a standard syringe;

Fig. 2 is a sectional view taken on line II-II of Fig. l;

Fig. 3 is a perspective view showing a frame for mounting and carrying the sterilizing means of my invention;

Fig. 4 is a sectional view of one of the cotton packs constituting the sterilizing means;

Fig. 5 is a plan view thereof;

Fig. 6 is a fragmentary sectional view of a modified form of sterilizing kit; and

Fig. 7 is a fragmentary sectional view of a modified form of attachment.

In the drawings 10 represents the barrel of any standard hypodermic syringe, and 11 the plunger thereof. The usual type needle 12 is shown attached to the barrel.

My device comprises a coupling collar 13 having a shoulder 14 for engagement with the bead 15 of the plunger 11 of the syringe. The shoulder 14 is formed with a bore 411S-for passage over the plunger 11 of the syringe. The collar Vis formed with a screwthreaded portion 2i) for engagement with the screwthreaded end 21 of 'the casing 22 of a sterilizing kit 23, to be hereinafter described. When the threaded end 21 of the casing'is engaged with the coupling collar, -the bead 15 will betightly clamped in position between the shoulder 14 and the end 21 of the casing.

A barrel clip 24 is provided with my attachment and this is clamped to the barrel at a point preferably where the spring gives the proper action. Suitable clamping means are provided for the clip, comprising a bolt 25 for passage through the tabs 26 of the clip, and a wing nut 30 carried by the bolt.

An actuating shaft 31 is passed between bearing portions 32 formed in the tabs 26 of the clip. This shaft extends outwardly toward the needle end of the barrel 10 so that when the plunger is in its innermost position, the actuating button 33 is near the outer end of the barrel. The inner end of the actuating shaft is preferably Screwthreaded and attached thereby to the coupling collar 13, whereby the plunger may be withdrawn from the cylinder by axial movement of the shaft. The side of the actuating shaft adjacent the bolt 25 is preferably formed with ratchet teeth or serrations 34 for engagement by a ratchet pawl 35 mounted between the tabs 26 of the clip. The ratchet pawl is carried by an actuating arm 36 which is pivotally mounted upon the bolt 25. A suitable spring il is provided for maintaining the ratchet pawl in position against the teeth of the ratchet.

A helical retracting spring 41 is mounted about the inner end of the actuating shaft 31 and has one end attached to the clip 24 and the other end to the coupling collar 13, whereby when the plunger has been withdrawn from the barrel by axial movement of the actuating shaft, it will be retracted or forced into the barrel when released and thereby discharge the medicine under pressure produced by the spring.

As is'well known to those skilled in the art, and particularlyby patients who have to take self-administered hypodermic treatments, an injection must be given many times at places where means for sterilizing the needle are not readily available. My invention, therefore, contemplates the use of a sterilizing kit which forms a part of the attachment. This kit comprises the hollow casing 22, hereinbefore referred to, which, together with the coupling collar 13, forms means for clamping the attachment to the plunger of the syringe. rl`his casing contains a plurality of cotton packs 42 which are disposed within the casing and which are preferably arranged one on top of the other.` Each of these packs is made preferably of cotton batting in the form of a disc 43 in which is imbedded a capsule 44 preferably of a soft -exible material and containing a quantity of a1- cohol or other suitable sterilizing solution. These packs are preferably disposed in a frame 45 comprising a base 45 and a top 50 joined by two side members 51. The top 56 is provided with a bale 52 by which the frame may be readily removed from the casing. The casing of the sterilizing kit is preferably formed with a base liange 53 which is considerably larger than the casing and which may be used as a support for the syringe when placed in a vertical position. lt will be obvious that when sosupported the needle of the syringe will be kept out of contact with the supporting surface whereby contamination thereof will be avoided.

In Fig. 6 I show a modied form of sterilizing kit for use upon a standard hypodermic syringe either with or without the spring tension portion of the attachment. in this form of device the casing 54 is formed with a bottom 55 for engagement with the bead 15 of the plunger 11. A number of spring clips 56 are carried by the bottom 55 of the casing and are designed to snap around the bead 15 of the plunger and to resiliently hold the casing in position thereon. This form of device is opened at the outer end where a pivotally mounted lid or cover 56 is' provided. This lid is formed with a spring catch 60 for engagement with the bead 61 formed at this end of the casing.

Should it be desired to use my attachment without the sterilizing unit 23, l provide a cap 61, shown in Fig. 7, to clamp the coupling collar to the bead of the syringe plunger. The cap is formed with a reduced threaded portion 62 for threaded engagement with the coupling collar and with a base ange 63 for supporting the syringe in a vertical position.

From the foregoing, it will be obvious that when a hypodermic syringe equipped with my invention is filled, the syringe may be supported by the ange 63 in a vertical position in which position the point of the needle will be prevented from touching the supporting surface and becoming contaminated thereby, Furthermore, when being administered, the medicine is forced out of a syringe eouinoed with my invention under spring tension when the ratchet nawl is released from the teeth of the actuating7 shaft. thereby administering the medicine under steady regulated flow and relieving the operator of the necessity of forcing the medicine into the body tissue, thereby avoiding unsteady movement or wobbling of the needle. made possible bv the use of my invention also avoids breakage of the syringe needles.

Should a patient find it necessary to administer a hypodermic inection where means of sterilization are not readily obtaintable, one of the cotton backs may be easily and quickly removed from the sterilizing kit, and the needle readily sterilized by piercing the pack and rupturing the capsule which causes the cotton to be impregnated with the sterilizing liquid, thereby making the needle ready for immediate use.

The sterilizing kit of Fig. 6 is shown as applied to a standard hypodermic syringe without the retracting spring and actuating shaft. Should, however, it be desired to use this form of sterilizing kit with the other portions of the attachment, it is only necessary that the casing 54 be provided with a lug (not shown) for the reception of the threaded end of the actuating shaft 31 and for the attachment of the inner end of the spring 41. These and other modifications of the details herein shown and described may be disclosed without departing from the spirit of my invention or the scope of the appended claims.

I claim:

1. An attachment for a hypodermic syringe having a barrel, a plunger slidable within the barrel and having a bead thereon, and a needle carried by the barrel, said attachment consisting of a sterilizing kit comprising a casing, a cover for the casing, means for demountably securing the casing to the bead of the plunger, and a plurality of sterilizing units carried bv the casing.

2. An attachment for a hypodermic syringe having a barrel, a plunger slidable within the barrel and having a bead thereon, and a needle carried by the barrel, said attachment consisting of a sterilizing kit comprising a casing, a cover for the casing, means for demountably securing the casing to the bead of the plunger, and a plurality of sterilizing units carried by the casing, each of the sterilizing units consisting of a disc of absorbent material and an ampoule imbedded in the disc and containing a sterilizing fluid.

3. The combination with a hypodermic syringe having a barrel, a beaded plunger slidable within the barrel, and a needle carried by the barrel, of an attachment comprising a clip for clamping to the barrel of the syringe, an actuating shaft slidably carried by the clip, a sterilizing kit, means for securing the sterilizing kit and the forward end of the actuating shaft to the bead of the plunger, and a retracting spring secured at one end to the clip and at the other end to the last named means.

4. The combination with a hypodermic syringe having a barrel, a beaded plunger slidably carried by the barrel, and a needle carried by the barrel, of an attachment comprising a clip secured to the barrel of the syr- The steady manipulation of the syringe inge, bead-engaging means carried by the plunger of the syringe, an actuating shaft slidably carried by the clip and having its forward end secured to the bead-engaging means, a helical spring mounted about the shaft and having its ends connected to the clip and to the bead-engaging means, and a sterilizing kit comprising a casing secured to the bead-engaging means and urging the same into engagement against the plunger bead, and a plurality of sterilizing packs carried by the casing.

5. An attachment for a hypodermic syringe having a barrel, a beaded plunger slidably carried by the barrel, and a needle carried by the barrel, said attachment comprising a clip adapted to be secured to the barrel of the syringe, bead-engaging means adapted to be carried by the plunger of the syringe, an actuating shaft slidably carried by the clip and having its forward end secured to the bead-engaging means, a helical spring mounted about the shaft and having its ends connected to the clip and to the bead-engaging means, and a sterilizing kit secured to the bead-engaging means and comprising a casing, and a plurality of sterilizing packs carried by the casing, each pack consisting of a cotton disc and an imbedded capsule containing sterilizing liquid.

6. An attachment for a hypodermic syringe having a barrel and a plunger with a bead thereon slidable in the barrel, comprising a coupling collar carried by the plunger of the syringe and engageable with the bead thereof, means for clamping the collar to the bead of the plunger, a clip secured to the barrel of the syringe, an actuating shaft carried by the clip and attached to the collar, and helical spring means connecting the collar to the clip.

7. An attachment for a hypodermic syringe having a barrel and a plunger movable lengthwise of the barrel,

the plunger having a bead thereon, comprising a cou-.

pling collar carried by the plunger of the syringe and engageable with the bead thereof, a sterilizing kit screwthreaded to the collar for clamping the latter to the plunger bead, a clip secured to the barrel of the syringe, an actuating shaft slidably carried by the clip and attached to the collar, and helical spring means connecting the collar to the clip.

8. An attachment for a hypodermic syringe having a barrel and a beaded plunger movable lengthwise thereof, comprising a coupling collar carried by the plunger of the syringe and engageable with the bead thereof, means for clamping the collar to the bead of the plunger, a clip secured to the barrel of the syringe, an actuating shaft slidably carried by the clip and attached to the collar, spring means connecting the coupling collar to the clip, and means for releasably retaining the actuating shaft in position, whereby the spring may be temporarily maintained under tension.

9. The combination with a hypodermic syringe having a barrel, a plunger slidably carried by the barrel, and a needle carried by the barrel, of an attachment comprising a clip secured to the barrel of the syringe7 a coupling collar secured to the plunger of the syringe, an actuating shaft carried by the clip and having its forward end secured to the collar, a helical spring mounted about the shaft and having its ends engageable with the clip and the collar, and a sterilizing kit secured to the collar, the kit comprising a casing, and a plurality of sterilizing packs carried by the casing.

References Cited in the file of this patent UNITED STATES PATENTS 2,198,666 Gruskin Apr. 30, 1940 FOREIGN PATENTS 15,888 Great Britain Aug. 23, 1895 562,328 Germany Oct. 24, 1932

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Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2863452A (en) * 1954-06-22 1958-12-09 Ogle Edna Syringe with adjustable aspirating means
EP0071289A1 (en) * 1981-07-27 1983-02-09 Duphar International Research B.V Automatic injection syringe
US4655226A (en) * 1983-12-16 1987-04-07 Southland Instruments, Inc. Disposable biopsy needle unit
US5115816A (en) * 1991-01-24 1992-05-26 Peter F. Lee, Inc. Single-hand controlled fine needle aspiration device
US5560373A (en) * 1994-04-11 1996-10-01 De Santis; Stephen A. Needle core biopsy instrument with durable or disposable cannula assembly
US5817033A (en) * 1994-04-11 1998-10-06 Desantis; Stephen A. Needle core biopsy device
US20010013554A1 (en) * 1999-09-09 2001-08-16 Scott Borland Aperture plate and methods for its construction and use
US6368308B1 (en) 1999-09-17 2002-04-09 Michael E. Nerney Syringe having forward-mounted plunger control
WO2003057291A1 (en) * 2002-01-07 2003-07-17 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US20030150445A1 (en) * 2001-11-01 2003-08-14 Aerogen, Inc. Apparatus and methods for delivery of medicament to a respiratory system
US20040004133A1 (en) * 1991-04-24 2004-01-08 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US20040035490A1 (en) * 2000-05-05 2004-02-26 Aerogen, Inc. Apparatus and methods for the delivery of medicaments to the respiratory system
US20040188534A1 (en) * 2001-05-02 2004-09-30 Aerogen, Inc. Base isolated nebulizing device and methods
US20040256488A1 (en) * 2001-03-20 2004-12-23 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US20050011514A1 (en) * 2003-07-18 2005-01-20 Aerogen, Inc. Nebuliser for the production of aerosolized medication
US20050080355A1 (en) * 2003-10-14 2005-04-14 Mark Joseph L. Vacuum assisted biopsy needle set
US20050172954A1 (en) * 2000-05-05 2005-08-11 Aerogen Inc. Methods and systems for operating an aerosol generator
US20050178847A1 (en) * 2002-05-20 2005-08-18 Aerogen, Inc. Methods of making an apparatus for providing aerosol for medical treatment
US20050199236A1 (en) * 2002-01-07 2005-09-15 Aerogen, Inc. Methods and devices for aerosolizing medicament
US20050205089A1 (en) * 2002-01-07 2005-09-22 Aerogen, Inc. Methods and devices for aerosolizing medicament
US20050217666A1 (en) * 2000-05-05 2005-10-06 Aerogen, Inc. Methods and systems for operating an aerosol generator
US20050229928A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US20050229926A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Method and composition for the treatment of lung surfactant deficiency or dysfunction
US20050229927A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Ventilation systems and methods employing aerosol generators
US7032590B2 (en) 2001-03-20 2006-04-25 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US7174888B2 (en) 1995-04-05 2007-02-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US20070044792A1 (en) * 2005-08-30 2007-03-01 Aerogen, Inc. Aerosol generators with enhanced corrosion resistance
US20070209659A1 (en) * 1995-04-05 2007-09-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US20070267010A1 (en) * 2000-05-05 2007-11-22 Fink James B Methods and systems for operating an aerosol generator
US20080017198A1 (en) * 2004-04-20 2008-01-24 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US20080200833A1 (en) * 2003-10-14 2008-08-21 Hardin Terry D Vacuum assisted biopsy device
US20090134235A1 (en) * 2005-05-25 2009-05-28 Aerogen, Inc. Vibration Systems and Methods
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US20110144684A1 (en) * 2006-06-15 2011-06-16 Abbott Diabetes Care Inc. Lancing devices having depth adjustment assembly
US8048003B2 (en) 2003-10-14 2011-11-01 Suros Surgical Systems, Inc. Vacuum assisted biopsy device
US20120059333A1 (en) * 2010-09-07 2012-03-08 Tara Chand Singhal Apparatus and methods for reuse of injection needle for home users
US8357103B2 (en) 2003-10-14 2013-01-22 Suros Surgical Systems, Inc. Vacuum assisted biopsy needle set

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB189515888A (en) * 1895-08-23 1896-07-04 William Evarts Richards Improvements in Syringes for Injecting Morphia, and for like purposes.
DE562328C (en) * 1931-01-20 1932-10-24 Koch Ernst Filling apparatus syringes
US2198666A (en) * 1936-09-30 1940-04-30 Lakeland Foundation Syringe

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB189515888A (en) * 1895-08-23 1896-07-04 William Evarts Richards Improvements in Syringes for Injecting Morphia, and for like purposes.
DE562328C (en) * 1931-01-20 1932-10-24 Koch Ernst Filling apparatus syringes
US2198666A (en) * 1936-09-30 1940-04-30 Lakeland Foundation Syringe

Cited By (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2863452A (en) * 1954-06-22 1958-12-09 Ogle Edna Syringe with adjustable aspirating means
EP0071289A1 (en) * 1981-07-27 1983-02-09 Duphar International Research B.V Automatic injection syringe
US4655226A (en) * 1983-12-16 1987-04-07 Southland Instruments, Inc. Disposable biopsy needle unit
US5115816A (en) * 1991-01-24 1992-05-26 Peter F. Lee, Inc. Single-hand controlled fine needle aspiration device
US20040004133A1 (en) * 1991-04-24 2004-01-08 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US7040549B2 (en) 1991-04-24 2006-05-09 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US5971939A (en) * 1994-04-11 1999-10-26 Laurus Medical Corporation Needle core biopsy device
US5560373A (en) * 1994-04-11 1996-10-01 De Santis; Stephen A. Needle core biopsy instrument with durable or disposable cannula assembly
US5817033A (en) * 1994-04-11 1998-10-06 Desantis; Stephen A. Needle core biopsy device
US8561604B2 (en) 1995-04-05 2013-10-22 Novartis Ag Liquid dispensing apparatus and methods
US20070209659A1 (en) * 1995-04-05 2007-09-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US7174888B2 (en) 1995-04-05 2007-02-13 Aerogen, Inc. Liquid dispensing apparatus and methods
US8398001B2 (en) 1999-09-09 2013-03-19 Novartis Ag Aperture plate and methods for its construction and use
US7066398B2 (en) 1999-09-09 2006-06-27 Aerogen, Inc. Aperture plate and methods for its construction and use
US20010013554A1 (en) * 1999-09-09 2001-08-16 Scott Borland Aperture plate and methods for its construction and use
US20070023547A1 (en) * 1999-09-09 2007-02-01 Aerogen, Inc. Aperture plate and methods for its construction and use
US6368308B1 (en) 1999-09-17 2002-04-09 Michael E. Nerney Syringe having forward-mounted plunger control
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US20070267010A1 (en) * 2000-05-05 2007-11-22 Fink James B Methods and systems for operating an aerosol generator
US7748377B2 (en) 2000-05-05 2010-07-06 Novartis Ag Methods and systems for operating an aerosol generator
US20080149096A1 (en) * 2000-05-05 2008-06-26 Aerogen, Inc. Apparatus and Methods for the Delivery of Medicaments to the Respiratory System
US20050172954A1 (en) * 2000-05-05 2005-08-11 Aerogen Inc. Methods and systems for operating an aerosol generator
US20050217666A1 (en) * 2000-05-05 2005-10-06 Aerogen, Inc. Methods and systems for operating an aerosol generator
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US7331339B2 (en) 2000-05-05 2008-02-19 Aerogen, Inc. Methods and systems for operating an aerosol generator
US20040035490A1 (en) * 2000-05-05 2004-02-26 Aerogen, Inc. Apparatus and methods for the delivery of medicaments to the respiratory system
US7322349B2 (en) 2000-05-05 2008-01-29 Aerogen, Inc. Apparatus and methods for the delivery of medicaments to the respiratory system
US8196573B2 (en) 2001-03-20 2012-06-12 Novartis Ag Methods and systems for operating an aerosol generator
US20040256488A1 (en) * 2001-03-20 2004-12-23 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7195011B2 (en) 2001-03-20 2007-03-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7032590B2 (en) 2001-03-20 2006-04-25 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US20080142002A1 (en) * 2001-03-20 2008-06-19 Aerogen, Inc. Methods and Systems for Operating an Aerosol Generator
US7104463B2 (en) 2001-05-02 2006-09-12 Aerogen, Inc. Base isolated nebulizing device and methods
US20040188534A1 (en) * 2001-05-02 2004-09-30 Aerogen, Inc. Base isolated nebulizing device and methods
US6978941B2 (en) 2001-05-02 2005-12-27 Aerogen, Inc. Base isolated nebulizing device and methods
US7600511B2 (en) 2001-11-01 2009-10-13 Novartis Pharma Ag Apparatus and methods for delivery of medicament to a respiratory system
US20030150445A1 (en) * 2001-11-01 2003-08-14 Aerogen, Inc. Apparatus and methods for delivery of medicament to a respiratory system
US20050205089A1 (en) * 2002-01-07 2005-09-22 Aerogen, Inc. Methods and devices for aerosolizing medicament
US20050199236A1 (en) * 2002-01-07 2005-09-15 Aerogen, Inc. Methods and devices for aerosolizing medicament
US20080184993A1 (en) * 2002-01-07 2008-08-07 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
US8539944B2 (en) 2002-01-07 2013-09-24 Novartis Ag Devices and methods for nebulizing fluids for inhalation
WO2003057291A1 (en) * 2002-01-07 2003-07-17 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US20050178847A1 (en) * 2002-05-20 2005-08-18 Aerogen, Inc. Methods of making an apparatus for providing aerosol for medical treatment
US7771642B2 (en) 2002-05-20 2010-08-10 Novartis Ag Methods of making an apparatus for providing aerosol for medical treatment
US20050011514A1 (en) * 2003-07-18 2005-01-20 Aerogen, Inc. Nebuliser for the production of aerosolized medication
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US7988642B2 (en) 2003-10-14 2011-08-02 Suros Surgical Systems, Inc. Vacuum assisted biopsy device
US8679032B2 (en) 2003-10-14 2014-03-25 Suros Surgical Systems, Inc. Vacuum assisted biopsy needle set
US20080221481A1 (en) * 2003-10-14 2008-09-11 Mark Joseph L Vacuum assisted biopsy needle set
US20050080355A1 (en) * 2003-10-14 2005-04-14 Mark Joseph L. Vacuum assisted biopsy needle set
US8430827B2 (en) 2003-10-14 2013-04-30 Suros Surgical Sysytems, Inc. Vacuum assisted biopsy device
US20080200833A1 (en) * 2003-10-14 2008-08-21 Hardin Terry D Vacuum assisted biopsy device
US8357103B2 (en) 2003-10-14 2013-01-22 Suros Surgical Systems, Inc. Vacuum assisted biopsy needle set
US8048003B2 (en) 2003-10-14 2011-11-01 Suros Surgical Systems, Inc. Vacuum assisted biopsy device
US7390306B2 (en) 2003-10-14 2008-06-24 Suros Surgical Systems, Inc. Vacuum assisted biopsy needle set
US8231544B2 (en) 2003-10-14 2012-07-31 Suros Surgical Systems, Inc. Vacuum assisted biopsy needle set
US7201167B2 (en) 2004-04-20 2007-04-10 Aerogen, Inc. Method and composition for the treatment of lung surfactant deficiency or dysfunction
US7290541B2 (en) 2004-04-20 2007-11-06 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US7267121B2 (en) 2004-04-20 2007-09-11 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US20050229926A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Method and composition for the treatment of lung surfactant deficiency or dysfunction
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
US20050229928A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US20080017198A1 (en) * 2004-04-20 2008-01-24 Aerogen, Inc. Aerosol delivery apparatus and method for pressure-assisted breathing systems
US20050229927A1 (en) * 2004-04-20 2005-10-20 Aerogen, Inc. Ventilation systems and methods employing aerosol generators
US20090134235A1 (en) * 2005-05-25 2009-05-28 Aerogen, Inc. Vibration Systems and Methods
US9108211B2 (en) 2005-05-25 2015-08-18 Nektar Therapeutics Vibration systems and methods
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