US2705949A - Biopsy needle - Google Patents

Biopsy needle Download PDF

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US2705949A
US2705949A US37630353A US2705949A US 2705949 A US2705949 A US 2705949A US 37630353 A US37630353 A US 37630353A US 2705949 A US2705949 A US 2705949A
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needle
tube
hub
flange
aperture
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Silverman Irving
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Silverman Irving
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • A61B10/0275Pointed or sharp biopsy instruments means for severing sample with sample notch, e.g. on the side of inner stylet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means

Description

April 12, 1955 l. SILVERMAN 2,705,949

BIOPSY NEEDLE Filed Aug. 25, 1953 FIG. I

INVENTOR. Irving Silvermcm I M 1 "a W AT ORNEY United States Patent BIOPSY NEEDLE Irving Silverrnan, Brooklyn, N. Y.

Application August 25, 1953, Serial No. 376,303

8 Ciaims. (Cl. 128-2) This invention relates to an improvement in my United States Patent No. 2,198,319 for a Biopsy Needle, issued April 23, 1940.

While my biopsy needle as disclosed in the above mentioned patent has satisfactorily met the need which it was conceived to meet, viz., to provide a means for removing samples of tissue from tumors, experience has indicated that improvements therein are possible which will make the needle an even greater aid to the surgeon. It will be recalled that the operational parts of the biopsy needle are in an inner split needle for grasping the tissue desired to be removed, and an outer tube within which the split needle can slide. The mode of operation is to first insert the split needle into the tissue, then insert the outer tube to enclose and compress the portions of the split needle together with the specimen of tissue therebetween, and remove the biopsy needle assembly, whereupon the specimens of tissue will be removed as well.

It will be apparent from an examination of the original patent that the operator of the device has no absolute way of knowing when the outer tube has been inserted to a point at which it covers the inner needle completely, but must rely on his good judgment. Should the outer tube not be introduced far enough, the result may be an inadequate grasp on the specimen to be removed by the inner needle and consequent failure to remove the specimen when the device is Withdrawn. Furthermore, if the tumor of which a specimen is desired is a dense one, the split portions of the inner needle may engage a large specimen, and when the outer tube is advanced for the purpose of covering the inner needle, the latter may not remain stationary but will advance further. Unnecessary trauma may result and the specimen may even slip out from between the split portions of the inner needle.

Accordingly, I have made an improvement in my biopsy needle by which these difiiculties may be overcome, and it may be said that the primary object of this invention is to overcome these difliculties.

One object of this improvement is to provide the operator with a means of knowing precisely when the outer needle has been advanced to a point where it covers the points of the inner needle.

Another object is to limit the range of movement of the inner needle so that once it has been inserted to the desired depth it can advance no further. This object especially encompasses the notion that the inner needle once having been inserted to the desired depth, may not be driven further by the action of the outer tube when it is subsequently inserted.

Still another object is to limit the range of movement of the outer tube so that it cannot be advanced further than a point just suflicient to be coextensive with the inner needle in its inserted position.

A further object is to provide a means for preventing rotation of the split needle after it has been inserted into the tumor and before the outer tube has been also inserted into the tumor. This object arises because instances have been known to occur where the device has been rotated after insertion of the inner needle, but before insertion of the outer tube, with the result that the split portions of the inner needle have been twisted beyond any hope of repair.

A still further object is to utilize the surface of the patients body in the vicinity of the tumor as a guide to control the extent of movement of the respective parts of the biopsy needle assembly.

Another object is to provide a means for aiding the operator to properly position and support the device in relation to the tumor before the specimen is taken.

Still another object is to keep at a minimum, trauma on the part of the patient by obviating unnecessary penetration of the inner split needle into the tumor, and by assuring that in most cases a specimen will be secured in a single attempt.

A final object is to accomplish all of the foregoing in as simple, eflicient and economical a manner as possible.

How these and many other objects are to be implemented will become apparent through consideration of the accompanying drawings wherein:

Fig. 1 is a side view of a biopsy needle and improvement thereon, in position before a specimen is taken,

Fig. 2 is a side view as in Fig. 1, after a specimen has been secured, but before the needle has been withdrawn,

Fig. 3 is a perspective view of one part in the present improvement, and

Fig. 4 is a perspective view of another part of the present improvement.

In the drawings there is shown a biopsy needle assembly 10 having an inner needle, 11. The penetrating part of needle 11 is comprised of two split portions 12 and 13. The other end of needle 11 is capped by the base 14 upon which pressure may be exerted to urge needle 11 into the tumor 15 of which a specimen is desired. Inner needle 11 passes through outer tube 16, the outer tube terminating at one end in hub 17 to which it is attached, hub 17 having a top 18 and bottom 19, outer tube 16 being beveled and pointed at its other end to facilitate insertion.

The outer tube 16 rests in carriage 20 having flanges 21 and 22 at either end, in such a manner that hub 17 has its top 18 in contact with flange 22, while tube 16 extends through an aperture 21a in flange 21. It should be noted particularly that the overall length of needle 11, exclusive of base 14, exceeds the length of tube 16 and hub 17 by an amount equal to the depth of penetration into the tumor desired, this desired depth being /3" in the embodiment shown in the drawings. The longitudinal dimension of carriage 20 is such that the distance from the bottom 19 of hub 17 to flange 21 is also equal to the depth of penetration into the tumor desired, the distance mentioned being measured when top 18 of hub 17 is in contact with flange 22. There is a hole 23 in carriage 20.

Lying exteriorly with respect to carriage 20 is the rack 24 having a single flange 25 at one end thereof in which there is an aperture 26, through which outer tube 16 may pass. Both carriage 2i and rack 24 are of rigid material. There is a slot 27 in rack 24.

A small bolt 30 passes through hole 23 in carriage 20 and slot 27 in rack 24. Nut 31 engages bolt 30 and may be tightened or loosened to render the mutual relationship between the carriage 20 and the rack 24 either fixed or movable. The portion of bolt 30 which passes through slot 27 is flat, on two sides so that bolt 30 will not turn when nut 31 is tightened down on it.

In order to prevent the operator from inadvertently rotating needle 11 independently of the remainder of the assembly, a portion 32 of the needle shaft adjacent to base 14 is square in cross section in the embodiment shown, and passes through a square aperture 33 in flange 22 of carriage 20.

In the actual operation of the assembly the outer tube 16 and associated hub 17 are placed in the carriage 20 with the tube passing through apertures 21a and 26 in carriage 20 and rack 24 respectively. Hub 17 rests in carriage 20 with the top 18 of the hub in contact with flange 22. The inner needle 11 is then inserted through aperture 33 and thence through the passage in the interior of outer tube 16 until the ends of split portions 12 and 13 just coincide with the beveled and pointed end of outer tube 16. The length of inner needle 11 is of such length that in this position the distance from base 14 to flange 22 will be equal to the depth of penetration into the tumor desired shown as A3" in the drawings, and will be the same distance as that between the bottom patient.

19 of hub 17 and flange 21, also in the drawings of the embodiment shown. Y

The skin 34 of the patient is then prepared, anaesthetized and an incision made. The biopsy needle assembly in the position just described is inserted :through the incision and just far enough to reach the surface of the tumor. The rack 24 is then movedwith respect to the carriage 20 until its flange comes into contact with the skin 34 of the patient. The functionof rack 24 is thus to aid the operator in positioning the device preparatory to taking a specimen, the flange 25 acting as a stop plate when it abuts against the skin of the Nut 31 is tightened to make the mutual relationship between rack 24 and carriage 20 fixed.

The inner needle 11 is then pushed into the tumor by exerting pressure on base 14 until the base comes into contact with the flange 22. Further progress of needle 11 is prevented by flange 25 abutting against the patients 'skin, as well as by base 14 coming into contact with flange 22. Outer tube 16 is then inserted until its further insertion is prevented when hub 17 comes into contact with flange 21. The operation is then complete; the assembly may be withdrawn together with the specimen of tissue there engaged.

While I have described a specific embodiment of my improvement it is obvious that modifications may be made therein without departing from the spirit of the invention.

I claim:

1. In a biopsy instrument for taking a specimen of tissue, having an outer tube and an inner split needle passing therethrough, said tube and said needle being capable of independent advancement, means for limiting the permitted distance of advancement of said tube to the same distance of advancement permitted for said needle, and means for positioning the ends of said tube and said needle at the surface of said tissue prior to advancement of said tube and said needle.

2. In a biopsy instrument having an outer tube and inner split needle passing therethrough, said tube and said needle being capable of independent advancement, means for limiting the permitted distance of advancement of said tube to the same distance of advancement permitted for said needle, and means for preventing rotation of said needle within said tube.

3. In a biopsy instrument for taking a specimen of tissue, having an outer tube and an inner split needle passing therethrough, said tube and said needle being capable of independent advancement, means for limiting the permitted distance of advancement of said tube to the same distance of advancement permitted for said needle, means for positioning the ends of said tube and said needle at the surface of said tissue prior to advancement of said tube and needle, and means for preventing rotation of said needle within said tube.

4. In a biopsy instrument having an outer tube at- 4 and the distance from one end of said hub to the aperture in said first mentionedflange-when the other-endof said hub is in contact with said second mentioned flange being also equal to the depth of penetration into said tissue desired.

6. In a biopsy instrument for taking a specimen of tissue from a mass of tissue lying beneath the surface of a body, said instrument having an outer tube attached to a hollow hub and an inner split needle passing interiorly through said tube and hub, said tube and said needle being capable of independent advancement, means for limiting thepcrmitted distance of advancement of said tube to t'ne s'ame distance of advancement permitted for said needle, said means having a strip of material with a flange at each end for accommodating said tube and hub, said strip having a hole therein, and a second means for positioning the ends of said tube and said needle at the surface of said tissue prior to advancement of said tube and said needle, said second meanscornprising a second strip of rigid material having a slot therein and a flange at one end thereof, an aperture in said flange, said tube passing through said aperture, a bolt passing through said hole in said first-mentioned strip and said slot in said second strip, and a nut engaging said bolt, whereby said second strip may be releasably fixed in varying position with respect to said first-mentioned strip.

7. In a biopsy instrument having an outer tube attached to a hollow hub and an inner split needle passing interiorly through said tube and hub, said tube and said needle being capable of independent advancement, means for limiting the permitted distance of advancement of said tube to the same distance of advancement permitted for said needle, said means comprising a rigid strip of material having a flange at either end, for accommodating said tube and hub, an aperture in one of said flanges, said tube passing through said aperture, a second aperture in the other of said flanges, said needle passing through said second aperture, said needle for a portion thereof having a cross-sectional shape other than circular, said last namedaperture having the same shape.

8. In a biopsy instrument for taking a specimen from a mass of tissue lying beneath the surface of a body, said instrument having an outer tube attached to a hollow hub and an inner split needle passing interiorly through said tube and hub, said tube and said needle being capable of independent advancement; means for limiting the permitted distance of advancement of said tube to the same distance permitted for said needle, said means comprising a rigid strip of material having a flange at either end, for accommodating said tube and hub, said strip having a hole therein, an aperture in the first of said flanges, said tube passing through said aperture, an aperture in the second of said flanges, said needle passing through said last named aperture, said needle tached to a hollow hub and an inner split needle passing interiorly through said tube and hub, with said tube and said needle being capable of independent advancement, means for limiting the permitted distance of advancement of said tube to the same distance of advancement permitted for said needle, said means comprising a rigid strip of material, having a flange at either end, for accommodating said tube and associated hub, an aperture in one of said flanges, said tube passing through said aperture, an aperture in the other of said flanges, said needle passing through said last named aperture.

5. In a biopsy instrument for taking a specimen from a mass of tissue lying beneath the surface of a body, said instrument having an outer tube attached to a hollow hub and an inner split needle passing interiorly through said tube and hub, said tube and said needle being capable of independent advancement, means for limiting the permitted distance of advancement of said tube to the same distance permitted for said needle. said means comprising a rigid strip of material having a flange at either end, for accommodating said tube and hub, an aperture in the first of said flanges, said tube passing through said aperture, an aperture in the second of said flanges, said needle passing through said last named aperture; said needle being greater in length than the combined length of said tube and hub by an amount equal to the depth of penetration into said tissue desired,

being greater in length than the combined lengths of said tube and hub by an amount equal to the depth of penetration into said tissue desired, and the distance from one end of said hub to the aperture in said first mentioned flange when the other end of said hub is in con tact with said second mentioned flange being also equal to the depth of penetration into said tissue desired; adjustable means for positioning the ends of said tube and said needle at the surface of said tissue prior to advancement of said tube and said needle, said means comprising a second strip of rigid material having a slot therein and a flange at one end thereof, an aperture in said flange, said tube passing through said aperture, a bolt passing through said hole in said first-mentioned strip and said slot in said second strip, and a nut engaging said bolt, whereby said second strip may be releasably Med in varying position with respect to said first mentioned strip; said needle for a portion thereof having a cross sectional shape other than circular, said aperture through which said needle passes having the same shape.

References Cited in the file of this patent UNITED STATES PATENTS 1,147,408 Kells July 20, 1915 2,198,319 Silverman Apr. 23, 1940 2,516,492 Turkel July 25, 1E0

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Cited By (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3477423A (en) * 1967-01-09 1969-11-11 Baxter Laboratories Inc Biopsy instrument
US3840008A (en) * 1972-04-18 1974-10-08 Surgical Corp Safety hypodermic needle
US3955558A (en) * 1974-11-04 1976-05-11 Medcom, Inc. Instrument for spinal taps
US4360016A (en) * 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
WO1985005024A1 (en) * 1984-05-07 1985-11-21 Hans Lee Method and apparatus for performing suction lipectomy
US4596553A (en) * 1984-05-07 1986-06-24 Hans Lee Method and apparatus for performing suction lipectomy
US4605011A (en) * 1983-03-23 1986-08-12 Naeslund Jan Ingemar Cell sampling apparatus
US4662870A (en) * 1985-07-15 1987-05-05 Augustine Scott D Needle penetration indicator and guide
US4676780A (en) * 1986-02-21 1987-06-30 Hans Lee Surgical apparatus for performing suction lipectomy
US4697586A (en) * 1986-06-24 1987-10-06 Gazale William J Combined chisel-guide surgical instrument
US4702261A (en) * 1985-07-03 1987-10-27 Sherwood Medical Company Biopsy device and method
US4713053A (en) * 1984-05-07 1987-12-15 Hans Lee Method and apparatus for performing suction lipectomy
US4917100A (en) * 1989-05-08 1990-04-17 Nottke James E Biopsy needle for use with spring-operated actuating mechanism
US4938743A (en) * 1984-05-07 1990-07-03 Hans Lee Surgical apparatus for performing suction lipectomy
US4966583A (en) * 1989-02-03 1990-10-30 Elie Debbas Apparatus for locating a breast mass
US4969870A (en) * 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
US5004457A (en) * 1988-12-02 1991-04-02 The United States Of Americas As Represented By The Secretary Of The Department Of Health And Human Services Tissue transplantation system
FR2654609A1 (en) * 1989-11-22 1991-05-24 Landos Applic Orthopediques Fs Support guide for biopsy needle
US5064414A (en) * 1989-07-28 1991-11-12 Angeion Corporation Locking clip with sheath and dilator
US5183463A (en) * 1989-02-03 1993-02-02 Elie Debbas Apparatus for locating a breast mass
US5217441A (en) * 1989-08-15 1993-06-08 United States Surgical Corporation Trocar guide tube positioning device
US5241969A (en) * 1992-06-10 1993-09-07 Carson Jay W Controlled and safe fine needle aspiration device
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
US5330501A (en) * 1991-05-30 1994-07-19 United States Surgical Corporation Tissue gripping device for use with a cannula and a cannula incorporating the device
US5336206A (en) * 1989-08-15 1994-08-09 United States Surgical Corporation Trocar penetration depth indicator and guide tube positioning device
US5445645A (en) * 1989-02-03 1995-08-29 Debbas; Elie Apparatus for locating a breast mass
WO1996024289A2 (en) * 1995-02-10 1996-08-15 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5562613A (en) * 1991-07-02 1996-10-08 Intermed, Inc. Subcutaneous drug delivery device
US5662674A (en) * 1989-02-03 1997-09-02 Debbas; Elie Apparatus for locating a breast mass
US5685856A (en) * 1996-02-27 1997-11-11 Lehrer; Theodor Coaxial blunt dilator and endoscopic cannula insertion system
US5738660A (en) * 1994-10-27 1998-04-14 Luther Medical Products, Inc. Percutaneous port catheter assembly and method of use
US5779647A (en) * 1995-06-07 1998-07-14 Chau; Sonny Automated biopsy instruments
US5807277A (en) * 1995-12-15 1998-09-15 Swaim; William R. Biopsy hand tool for capturing tissue sample
US5817052A (en) * 1995-12-26 1998-10-06 Pyng Medical Corp. Apparatus for intraosseous infusion or aspiration
US5882344A (en) * 1995-10-18 1999-03-16 Stouder, Jr.; Albert E. Adjustable length cannula and trocar
US5906599A (en) * 1995-11-09 1999-05-25 Intermed, Inc. Device for delivering biological agents
US5928164A (en) * 1994-03-24 1999-07-27 Ethicon Endo-Surgery, Inc. Apparatus for automated biopsy and collection of soft tissue
US6017316A (en) * 1997-06-18 2000-01-25 Biopsys Medical Vacuum control system and method for automated biopsy device
EP0979637A1 (en) * 1998-08-11 2000-02-16 Hakko Electric Machine Works Co. Ltd. Device for guiding puncture needle
US6142955A (en) * 1997-09-19 2000-11-07 United States Surgical Corporation Biopsy apparatus and method
WO2000064354A3 (en) * 1999-04-26 2001-03-08 Scimed Life Systems Inc Apparatus and methods for guiding a needle
US6293952B1 (en) 1997-07-31 2001-09-25 Circon Corporation Medical instrument system for piercing through tissue
EP1095625A3 (en) * 1999-10-29 2001-10-04 Tuebingen Scientific Surgical Products OHG Instruments support structure in particular for minimally invasive surgery
US6402701B1 (en) 1999-03-23 2002-06-11 Fna Concepts, Llc Biopsy needle instrument
US6423034B2 (en) * 1997-01-08 2002-07-23 Symbiosis Corporation Endoscopic infusion needle having dual distal stops
US6471711B2 (en) 1998-08-11 2002-10-29 Hakko Electric Machine Works, Co. Ltd. Device for guiding puncture needle
US20030114862A1 (en) * 2001-12-14 2003-06-19 Chu Michael S.H. Methods and apparatus for guiding a needle
US20030216667A1 (en) * 2000-09-11 2003-11-20 Frank Viola Biopsy system
US6659996B1 (en) 1995-11-09 2003-12-09 Intermed, Inc. Device for delivering biological agents
US6689142B1 (en) 1999-04-26 2004-02-10 Scimed Life Systems, Inc. Apparatus and methods for guiding a needle
US20040153002A1 (en) * 2003-01-31 2004-08-05 Schramm John B. Integrated biopsy needle assembly
US20040225229A1 (en) * 2000-11-27 2004-11-11 Viola Frank J. Tissue sampling and removal apparatus and method
NL1027561C2 (en) * 2004-11-23 2006-05-24 Isodose Control Intellectual P The insertion device for the insertion of a catheter.
US20080132804A1 (en) * 2006-12-01 2008-06-05 Stephens Randy R Remote Thumbwheel For Surgical Biopsy Device
US20080208136A1 (en) * 1998-05-15 2008-08-28 Pyng Medical Corp. Bone-penetrating member for intraosseous infusion and aspiration devices
US20100113972A1 (en) * 2008-10-31 2010-05-06 Victor Hugo Alvarado Biopsy needle device and method for using same
DE10062143B4 (en) * 1999-12-14 2011-05-26 Hoya Corp. Control panel for an endoscopic treatment instrument
US9180276B2 (en) 2010-03-26 2015-11-10 Terumo Kabushiki Kaisha Method involving use of an assembled indwelling assembly

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US2198319A (en) * 1938-10-29 1940-04-23 Silverman Irving Biopsy needle
US2516492A (en) * 1950-02-09 1950-07-25 Turkel Henry Skin biopsy needle

Cited By (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3477423A (en) * 1967-01-09 1969-11-11 Baxter Laboratories Inc Biopsy instrument
US3840008A (en) * 1972-04-18 1974-10-08 Surgical Corp Safety hypodermic needle
US3955558A (en) * 1974-11-04 1976-05-11 Medcom, Inc. Instrument for spinal taps
US4360016A (en) * 1980-07-01 1982-11-23 Transidyne General Corp. Blood collecting device
US4605011A (en) * 1983-03-23 1986-08-12 Naeslund Jan Ingemar Cell sampling apparatus
WO1985005024A1 (en) * 1984-05-07 1985-11-21 Hans Lee Method and apparatus for performing suction lipectomy
US4596553A (en) * 1984-05-07 1986-06-24 Hans Lee Method and apparatus for performing suction lipectomy
US4713053A (en) * 1984-05-07 1987-12-15 Hans Lee Method and apparatus for performing suction lipectomy
US4627834A (en) * 1984-05-07 1986-12-09 Hans Lee Apparatus for performing suction lipectomy
US4938743A (en) * 1984-05-07 1990-07-03 Hans Lee Surgical apparatus for performing suction lipectomy
US4702261A (en) * 1985-07-03 1987-10-27 Sherwood Medical Company Biopsy device and method
US4662870A (en) * 1985-07-15 1987-05-05 Augustine Scott D Needle penetration indicator and guide
US4676780A (en) * 1986-02-21 1987-06-30 Hans Lee Surgical apparatus for performing suction lipectomy
US4697586A (en) * 1986-06-24 1987-10-06 Gazale William J Combined chisel-guide surgical instrument
US5004457A (en) * 1988-12-02 1991-04-02 The United States Of Americas As Represented By The Secretary Of The Department Of Health And Human Services Tissue transplantation system
US5662674A (en) * 1989-02-03 1997-09-02 Debbas; Elie Apparatus for locating a breast mass
US5183463A (en) * 1989-02-03 1993-02-02 Elie Debbas Apparatus for locating a breast mass
US4966583A (en) * 1989-02-03 1990-10-30 Elie Debbas Apparatus for locating a breast mass
US5445645A (en) * 1989-02-03 1995-08-29 Debbas; Elie Apparatus for locating a breast mass
US4917100A (en) * 1989-05-08 1990-04-17 Nottke James E Biopsy needle for use with spring-operated actuating mechanism
EP0476047A1 (en) * 1989-06-07 1992-03-25 Univ California Method and apparatus for intraosseous infusions and aspirations.
EP0476047A4 (en) * 1989-06-07 1992-04-22 The Regents Of The University Of California Method and apparatus for intraosseous infusions and aspirations
US4969870A (en) * 1989-06-07 1990-11-13 The Regents Of The University Of California Method and apparatus for intraosseous infusions
US5064414A (en) * 1989-07-28 1991-11-12 Angeion Corporation Locking clip with sheath and dilator
US5336206A (en) * 1989-08-15 1994-08-09 United States Surgical Corporation Trocar penetration depth indicator and guide tube positioning device
US5370625A (en) * 1989-08-15 1994-12-06 United States Surgical Corporation Trocar guide tube positioning device
US5217441A (en) * 1989-08-15 1993-06-08 United States Surgical Corporation Trocar guide tube positioning device
FR2654609A1 (en) * 1989-11-22 1991-05-24 Landos Applic Orthopediques Fs Support guide for biopsy needle
US5330501A (en) * 1991-05-30 1994-07-19 United States Surgical Corporation Tissue gripping device for use with a cannula and a cannula incorporating the device
US5562613A (en) * 1991-07-02 1996-10-08 Intermed, Inc. Subcutaneous drug delivery device
US5241969A (en) * 1992-06-10 1993-09-07 Carson Jay W Controlled and safe fine needle aspiration device
US5312364A (en) * 1993-08-06 1994-05-17 Pyng Intraosseous infusion device
US7981050B2 (en) 1994-03-24 2011-07-19 Devicor Medical Products, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US7226424B2 (en) 1994-03-24 2007-06-05 Ethicon Endo-Surgery, Inc. Methods and devices for automated biopsy and collection of soft tissue
US20040019299A1 (en) * 1994-03-24 2004-01-29 Ritchart Mark A. Methods and devices for automated biopsy and collection of soft tissue
US20070156064A1 (en) * 1994-03-24 2007-07-05 Ritchart Mark A Methods and Devices for Automated Biopsy and Collection of Soft Tissue
US20080154151A1 (en) * 1994-03-24 2008-06-26 Ritchart Mark A Methods and Devices for Automated Biopsy and Collection of Soft Tissue
US20100063415A1 (en) * 1994-03-24 2010-03-11 Ritchart Mark A Methods and devices for automated biopsy and collection of soft tissue
US6428486B2 (en) 1994-03-24 2002-08-06 Ethicon Endo-Surgery, Inc. Methods and devices for automated biopsy and collection of soft tissue
US7794411B2 (en) 1994-03-24 2010-09-14 Devicor Medical Products, Inc. Methods and devices for automated biopsy and collection of soft tissue
US7918803B2 (en) 1994-03-24 2011-04-05 Devicor Medical Products, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5928164A (en) * 1994-03-24 1999-07-27 Ethicon Endo-Surgery, Inc. Apparatus for automated biopsy and collection of soft tissue
US5980469A (en) * 1994-03-24 1999-11-09 Ethicon Endo-Surgery, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US8808199B2 (en) 1994-03-24 2014-08-19 Devicor Medical Products, Inc. Methods and devices for biopsy and collection of soft tissue
US20110160611A1 (en) * 1994-03-24 2011-06-30 Devicor Medical Products, Inc. Methods and devices for biopsy and collection of soft tissue
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