US2697315A - Vacuum strip retention - Google Patents

Vacuum strip retention Download PDF

Info

Publication number
US2697315A
US2697315A US193946A US19394650A US2697315A US 2697315 A US2697315 A US 2697315A US 193946 A US193946 A US 193946A US 19394650 A US19394650 A US 19394650A US 2697315 A US2697315 A US 2697315A
Authority
US
United States
Prior art keywords
capsule
vacuum
strip
die
roll
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US193946A
Other languages
English (en)
Inventor
Stirn Frank Edwin
Taylor Arthur Sinclair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to US193946A priority Critical patent/US2697315A/en
Priority to CH295459D priority patent/CH295459A/fr
Priority to GB25563/51A priority patent/GB706805A/en
Application granted granted Critical
Publication of US2697315A publication Critical patent/US2697315A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use

Definitions

  • VACUUM STRIP RETENTION Filed Nov. 3, 1950 Sheets-Sheet 2 Jaw Mfzlkv- ATTO R N EY United States Patent VACUUM STRIP RETENTION Frank Edwin Stirn, Pearl River, and Arthur Sinclair Taylor, Spring Valley, N. Y., assignors to American Cyanamid Company, New York, N. Y., a corporation of Maine Application November 3, 1950, Serial No. 193,946
  • This invention relates to improvements in a method and mechanisms for forming and filling capsules from soft elastic strip material such as gelatin, whichcapsules may be filled with any desired material, and relates particularly to a method of retaining the strip on the surface of the die, in such fashion as to avoid slippage and to prevent variations in size of the capsule and to permit the obtaining of straight, evenly-formed capsules.
  • capsules have been produced but all too frequently there has been a previously unexplained variation in the size and also an unexplained irregularity in shape, particularly in the long cylindrical form of capsules with rounded ends referred to in the trade as flat ovals. They frequently have had a heliform or worm-shape; they have come out with various types of configurations like a kidney bean or a jelly bean, rather than a straight, symmetrical, evenlyformed capsule as is desired.
  • our method of retaining the strip in position is of particular value if the strip is coated on what is to become the inside of the capsule with an adhesive material such as a silicone resin or gum benzoin, or shellac, etc. If such a coating is used, it is desirable that none of the feeding or forming mechanisms contact the strip after the coating is applied. Our method of strip retention is particularly useful under such circumstances.
  • Our new type of hold-down dies may be used to position the strip in capsuling machines like those shown in our co-pending application Serial No. 164,426 filed May 26, 1950 for use with a single die roll against the fiat sealing roll.
  • Our vacuum strip hold-down may be used in machines like those shown by Scherer 1,970,396 to retain the strip in position while the capsule cavities are being formed.
  • Our vacuum strip hold-down may be used also in machines like those shown in Weckesser 2,323,581 and those shown by Cowley 2,387,747. Such machines are doublesided and vacuum strip retention is preferably to be used I on each roll.
  • Our vacuum strip retention may also be used for submerged filling like that shown by Pittenger 2,219,578 and may be used with either the double roller or the roll and flat die form shown by him.
  • Figure l is a surface view of a capsule die roll for flat oval capsules.
  • Figure 2 is a sectional view along line 2-2 of Figure 1 showing the manifold passages.
  • Figure 3 is a modification of our invention showing round capsule dies.
  • Figure 4 is a modification of our invention showing a separate vacuum system for the hold-down.
  • Figure 5 is a sectional view along line 5-5 of Figure 4 showing a manifold system for use with separate holddown ducts, showing the strip with the retention vacuum applied, before the application of the capsule cavityforming vacuum.
  • FIG. 1 there is shown a cavity die roll 11 having in its surface capsule cavity inserts 12. These inserts may be a press fit in insert slots 13. Each of the capsule cavity inserts has a cutting out rim 14 over which a deformable strip material 15 is placed. Normally a soft gelatin film is preferred for capsule work; various substitutes for gelatin may be used for this strip. Under the capsule cavity inserts, there may be a capsule ejector piston cylinder 16 in which fits a capsule ejector piston 17 to which is attached a capsule ejector plug 18. To the cylinder 16 is connected a manifold 19 which connects the cylinders with a valve seat surface 20 of the cavity die roll. On this surface rests a valve plate 21 in which there is a vacuum chest 22 to which a vacuum connection 23 is attached.
  • This general form of die roll is described in our earlier applications, Serial Nos. 164,426 and 174,748.
  • a restricted passage, 24 serves as a vacuum bleed during the forming cycle of capsuling operations. This passage should be very small, but in the drawings is accen: tuated so as to be visible.
  • gelatin film feeds towards the surfacetofthe .cavitydie roll, it hasthe tendency to lay fiatonithesurfaces .of-Ithe rims and must be pulled down intorcontact with the die roll.-both.inside and outside'of thecavities by the reduction of'pressure under the strip; It is desirablelthat the passages be ofsuch size as .to give a reduced pressure zone over the entire arc oficontact, anfparti'cularly; at ithepoint of actual. fill.,
  • Ah independent'hole to the'surface of the cavity die roll from the manifold passage 19 may be used.
  • Theoseparatevacuum chest'and passages permit the holdingtvacuum to be'independentlyapplied, prior to, simultaneously with, orrsubsequentto --the.;.capsule shell formingsvacuumrin the cavity die' inserts... With zaisingle. vacuum. .chest, and a single manifoldsystem, the 1 capsule shellj forming-- vacuum;.which .pulls; the gelatin 1 strip into the-:cap'sule :cavity, is 5 simultaneous with. the strip hold down vacuum.
  • a variation in the bleed vacuum applied through the bleed. vacuum. connection. can..increase or. decreasecthe...
  • a capsule-::dieroll which comprisesplacing the-strip adjacent the-surface of-the'die-roll' and* reducing the-pressure in" capsule-cavities in th'e'die' roll' surface, therebyformingpockets' inthe strip, and-in dependently and separately controllably' reducing the pressure under theportion ofi'the strip outside ofthecapsule cavities, thereby-retaining thestrip in position;
  • cavities whereby pressure between theelasticstrip and the die roll blank. but outside: of .the capsule forming cavities may be independently controlled..-

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
US193946A 1950-11-03 1950-11-03 Vacuum strip retention Expired - Lifetime US2697315A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US193946A US2697315A (en) 1950-11-03 1950-11-03 Vacuum strip retention
CH295459D CH295459A (fr) 1950-11-03 1951-10-30 Procédé de fabrication de capsules et dispositif pour la mise en oeuvre de ce procédé.
GB25563/51A GB706805A (en) 1950-11-03 1951-11-01 Improvements relating to capsules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US193946A US2697315A (en) 1950-11-03 1950-11-03 Vacuum strip retention

Publications (1)

Publication Number Publication Date
US2697315A true US2697315A (en) 1954-12-21

Family

ID=22715681

Family Applications (1)

Application Number Title Priority Date Filing Date
US193946A Expired - Lifetime US2697315A (en) 1950-11-03 1950-11-03 Vacuum strip retention

Country Status (3)

Country Link
US (1) US2697315A (fr)
CH (1) CH295459A (fr)
GB (1) GB706805A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040111277A1 (en) * 2002-12-06 2004-06-10 Pearson Walter G. Drug packaging machine & printing software for same
US20230106844A1 (en) * 2016-07-30 2023-04-06 CAPTEK® Softgel International Die roll for forming soft gel capsules

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716680C2 (de) * 1977-04-15 1979-12-20 Adolf Illig Maschinenbau Gmbh & Co, 7100 Heilbronn Vorrichtung zum Formen, Stanzen und Stapeln von Teilen aus thermoplastischer Kunststoffolie

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1629154A (en) * 1926-06-30 1927-05-17 Ybarrondo Vincent C De Pneumatic pulley for motion-picture films
US1654647A (en) * 1921-07-23 1928-01-03 Penn Rubber Products Corp Method of making hollow articles
US2152101A (en) * 1935-10-28 1939-03-28 Robert P Scherer Method and apparatus for making capsules by submerged filling action
US2219578A (en) * 1936-12-19 1940-10-29 Sharp & Dohme Inc Manufacture of medicinal capsules
US2308453A (en) * 1939-05-20 1943-01-12 John F Neary Jr Apparatus for manufacturing laminated material
US2376805A (en) * 1943-08-03 1945-05-22 Columbian Rope Co Molding apparatus
US2524419A (en) * 1946-03-01 1950-10-03 Vacuum Concrete Inc Apparatus and method for utilizing vacuum in molding plastic material, such as concrete

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1654647A (en) * 1921-07-23 1928-01-03 Penn Rubber Products Corp Method of making hollow articles
US1629154A (en) * 1926-06-30 1927-05-17 Ybarrondo Vincent C De Pneumatic pulley for motion-picture films
US2152101A (en) * 1935-10-28 1939-03-28 Robert P Scherer Method and apparatus for making capsules by submerged filling action
US2219578A (en) * 1936-12-19 1940-10-29 Sharp & Dohme Inc Manufacture of medicinal capsules
US2308453A (en) * 1939-05-20 1943-01-12 John F Neary Jr Apparatus for manufacturing laminated material
US2376805A (en) * 1943-08-03 1945-05-22 Columbian Rope Co Molding apparatus
US2524419A (en) * 1946-03-01 1950-10-03 Vacuum Concrete Inc Apparatus and method for utilizing vacuum in molding plastic material, such as concrete

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040111277A1 (en) * 2002-12-06 2004-06-10 Pearson Walter G. Drug packaging machine & printing software for same
US7650732B2 (en) * 2002-12-06 2010-01-26 Pearson Medical Technologies, Inc. Drug packaging machine & printing software for same
US20230106844A1 (en) * 2016-07-30 2023-04-06 CAPTEK® Softgel International Die roll for forming soft gel capsules

Also Published As

Publication number Publication date
CH295459A (fr) 1953-12-31
GB706805A (en) 1954-04-07

Similar Documents

Publication Publication Date Title
US2775080A (en) Method of forming powder-and-liquid filled capsules
US2697315A (en) Vacuum strip retention
KR920703029A (ko) 필름이 에워싸여진 하나의 코어를 갖는 알약과 그 유사품
CA966728A (en) Distributing device for a sowing machine
US2663128A (en) Method and machine for making capsules
US2697317A (en) Capsule forming die roll
US2663130A (en) Apparatus for producing symmetrical generally ellipsoidal capsules
US2775081A (en) High density encapsulation
YU180272A (en) Device for manufacturing articles provided wit an internal thread, by pressure casting
US2663129A (en) Machine for fabricating capsules from elastic films
CN109574772A (zh) 一种异形炸药柱成型模具
GB953916A (en) Improvements relating to rolling seal diaphragms
GB1268439A (en) Improvements relating to closure caps
US2902802A (en) Encapsulating die roll system
US3831423A (en) Method of making golf ball molds
US3593380A (en) Molding plate of a press mold for making articles of blanks of loose materials
US2252758A (en) Method of making diaphragms
GB2043581A (en) Method and apparatus for the manufacture of one-piece capsules
US3081234A (en) Soft elastic capsules and process for producing
US2367802A (en) Feeder head
US2363059A (en) Core for golf balls or the like and method of making
GB709784A (en) Improvements in or relating to capsules
GB1429116A (en) Pressing hollow glass articles
US2203457A (en) Stenciling apparatus
US2653737A (en) Method and means for blocking hats