US2687838A - Ampoule filling device - Google Patents

Ampoule filling device Download PDF

Info

Publication number
US2687838A
US2687838A US20842251A US2687838A US 2687838 A US2687838 A US 2687838A US 20842251 A US20842251 A US 20842251A US 2687838 A US2687838 A US 2687838A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
ampule
carriage
neck
ampules
track
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
Vernon H Wallingford
Jr Frank L Mackey
Kelley Horace Leo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Chemical Works
Original Assignee
Mallinckrodt Chemical Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00Packaging plastic material, semi-liquids, liquids, or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B3/003Filling medical containers such as ampoules, vials, syringes or the like

Description

Aug. 31, 1954 Filed Jan, 29, 1951 v. H. 'WALLINGFORD ETAL AMPOULE FILLING DEVICE 2 Sheets-Sheet l A g- 31, 1 54 v. H. WALLINGFORD ETAL 2,687,338

AMPOULE FILLING DEVICE Filed Jan. 29. 1951 2 Sheets-Sheet 2 Patented Aug. 31, 1954 UNITED STATES PATENT OFFICE Anroum jriij fic nn'vroc 8 Vernon H. Wallingford, Ferguson, and Frank L. Mackey, .Ir., and Horace Leo Kelley, St. Louis, Mo., assignors to Mallinckrodt Chemical Works, St. Louis, M0,, acorporation of Missouri Ap lication January 29, 1951, Serial No. 208,422

This invention relates to ampule filling devices, and more particularly to devices for use in filling glass ampules of the type having a neck, the neck having an intermediate narrow section, the ampule being hermetically sealed after it has been filled by flame-sealing the neck. The object of the invention is the provision of a device for facilitating the filling of necked am: pules by enabling an ampule easily and quickly to be accurately positioned in aligned relation with respect to an ampule filling needle, and then quickly moved into a filling position wherein the needle extends completely through the neck of the ampule with its discharge end entered within the body of the ampule. This enables necked ampules to be filled quickly without wetting the ing if their necks were wet on the inside in the.

region of sealing.

In general, an ampule filling device of this invention comprises an inclined track and an ampule filling needle carried by the track extending downward in cantilever fashion from the upper end of the track above and generally parallel to the track. The needle is supported for universal adjustment of the position of its axis. The needle has a discharge opening at its lower end, and its upper end is adapted for connection ofthe supply tube leading from the outlet of a pump for dispensing a liquid with which the ampules are to be filled. A carriage adapted to hold a necked ampule with the neck extending upward in accurate alignment with the needle is slidable on the track between a lower retracted position, wherein an ampule may be placed on the carriage, and a raised filling position, determined by engagement of the carriage with a stop on the track, wherein the needle extends completely through the neck of the ampule with the lower discharge end of the needle entered in the.

body or the ampule. Other features will be in part apparent and in part pointed out hereim.

Fig. 1 isa view in side elevation of an ampulel 9 Claims. (Cl. 226 493) filling device embodying the invention, a carriage thereof being shown in retracted position;

Fig. 2 is a view of Fig. l as viewed from the line 2--2 of Fig. 1, parts being shown in section;

Fig. 3 is a view similar to Fig. 2, illustrating the carriage in filling position;

Fig. 4 is an enlarged section taken on line 4-8 of Fig. 1;

Fig. 5 is an enlarged of l;

Fig. 6 is an enlarged section taken on line 6 6 of Fig. 1;

Fig. 7 is an enlarged section taken on line l--"l of Fig. l; Fig. Sis an enlarged section taken on line 8-4! of Fig. l; and,

Fig. 9 is a fragmentary view illustrating how an ampule filling needle extends through the neck of an ampule in filling position.

Similar reference characters indicate corresponding parts throughout the several views of the drawings.

The drawings illustrate a preferred embodiment of the invention for simultaneously filling two long-necked ampules i of the type shown in solid lines in Figs. 3 and 9 and in dotted lines in Fig. 1. As illustrated, each ampule, made of section taken on line 5-43 glass, consists of a cylindrical body 3 having a fiat bottom 5 and a long neck I. Adjacent the body 3, theneck is narrow, then develops sharply into a wider section, then tapers toward a narrow intermediate section 8 Where it is to be flamesealed. From the narrow section 8, the neck flares out to its upperopen end 9. Ampules of this type, as supplied by the manufacturer, are not always uniform. In some instances the diameter of the neck or the body may vary, or the axis of the neck may not coincide with the axis of the body. For example, the neck may be inclined with respect to the axis of the body, or parallel to but offset from the axis of the body. This invention provides a device for filling these ampules which makes it possible accurately to align'the neck of an ampule with a filling needle and to move the ampule into filling position wherein the needle extends completely through the neck in such manner as to avoid any possibility of wetting the narrow section 8 of the neck of the ampule, taking into account the possibility of non-uniformity of ampules.

In general, the embodiment of the invention shown in the drawings comprises a carriage or slide it for holding two ampules side-byside. The carriage is slidable up and down on an inclined track gene-rally designated it. A pair of ampule filling needles I5, of smaller diameter than the minimum inside diameter of the neck in its narrow section 8, are carried by the track at is upper end, and extend downward in cantilever fashion from the upper end of the track above and generally parallel thereto. Each needle has a discharge opening I! at its lower end. The upper ends 19 of the needles are adapted for the connection thereto of supply tubes 2| connected to a pump (not shown) for dispensing the liquid with which the ampules are to be filled.

More particularly, the device illustrated in the drawings comprises a stand consisting of a horizontal base plate 23 and a vertical post 25 extending upward from the base plate adjacent its rearward end. The track I3 comprises an angle bar 21 mounted in inclined position extending from adjacent the forward end of the base plate over the upper end of the post. A pair of V- shaped angle bar rails 29 are mounted side-byside on the bar 2'5. The inclination of the rails is preferably about 45. As shown, the bar 2'! is inverted so that its legs are downwardly divergent, and the rails 29 are mounted on the outer sides of the legs of the bar 2'! with their legs upwardly divergent.

Each needle 15 has an enlarged portion 3| adjacent its upper end which is slidably fitted in a sleeve 33 (see Figs. 2 and 4). At the upper ends of the rails 29 are open-ended cylinders 35 mounted side-by-side with their axes parallel to and above the rails. The cylinders are cradled in and secured to V-shaped spacers 31 fixed in the rails at their upper ends. The sleeves 33, carrying the needles 55, are adjustably held in position in the cylinders by upper and lower series of set screws 39 and 4 I, respectively, threaded radially in the cylinders at approximate 120 intervals, thereby providing two adjustable threepoint mountings for each needle spaced axially along the length of the needle. This enables each needle to be universally adjusted to extend parallel, or at least substantially parallel, to its respective rail, and at different distances from the rail. Each needle has a collar 43 abutting the upper end of the respective sleeve, and is fixed in the sleeve by set screws 45 and 41 threaded in the sleeve above and below the respective cylinder 35.

The carriage H comprises a pair of V-shaped slides 49 slidable in the V-shaped rails 29. The V-shaped slides 49 are held together adjacent their upper end by a bridge member and are retained in the rails by angle clips 53 (see Figs. 1, 2 and 6). At their lower ends, the slides are held together by a bottom plate 55 in a plane at right angles to the rails. Fixed in the slides 49 adjacent their lower ends are V-shaped cradles 5'? each having a narrow arcuate rim 59 abutting and secured to the plate 55. The cradles are V-shaped to hold the cylindrical bodies 3 of the ampules with the necks of the ampules extending generally parallel to the track, and with the bottoms oi; the ampules retained within the rims 59 in engagement with the bottom plate 55. Each slide 55 is provided with a centering member 6| for supportin the narrow section 8 of the neck of any ampule in a laterallyand vertically centered position as regards the carriage and the track. Preferably, member 6| is a spring clip, as illustrated, for receiving the narrow section 8 of the neck of any ampule and releasably gripping the neck. This arrangement insures that the narrow section 8 of the neck of any ampule is located in the same laterally and vertically centered position as the narrow section of the neck of any other ampule, despite variations in the ampules as above mentioned. This is important to assure substantial concentricity of the narrow sections of the necks of all ampules with the filling needles l5, so that the needles may pass centrally through the narrow sections without touching the glass. The needles are adjusted by means of set screws 39 and ll to secure axial alignment thereof with the narrow sections of the necks of the ampules mounted in the carriage.

The carriage It is manually slidable on the track 13 between the lower retracted position illustrated in Figs. 1 and 2, and the raised filling position illustrated in Figs. 3 and 9. The lower retracted position of the carriage is determined by the engagement of its bottom plate with a lower stop 63 on the base plate. The raised filling position of the carriage is determined by engagement of the bridge member 5! of the carriage with an upper stop 55 adjustably mounted on the track. The stop 83 is spaced from the lower discharge ends of the needles l5 a distance measured along the inclined track somewhat greater than the length of the ampules to be filled, so that when the carriage is retracted, it is clear of the needles so that ampules may be placed therein. When the carriage is in retracted position, the stop 55 is spaced from the bridge member 5i a distance measured along the track greater than the length of the neck of the ampule to the extent that when the carriage is moved to filling position, the needles will extend completely through the necks of the ampules with their lower discharge ends entered in the cylindrical bodies 3 of the ampules. Stop 55 comprises a screw adjustably threaded in a bridge member 51 secured to the rails adjacent the lower ends of the cylinders 35 (see Figs. 1, 2, 3 and 5). The stop or screw 55 extends parallel to and above the track. It is retained in adjusted position by a set screw 59, and provided with a collar "H acting as a detent in conjunction with a spring latch l3 carried by the bridge member 5| of the carriage, the latch engaging the detent releasably to hold the carriage in its raised filling position. The stop 65 may be threaded into or out of the bridge member 5? to vary the distance which the needles extend into the ampules.

In use, the carriage l l is placed in its retracted position of Figs. 1 and 2, and two ampules are placed neck upward in the cradles 51, their necks being clipped in clips M. This properly centers the narrow sections 8 of the necks of the ampules with the filling needles i5, simply by the act of placing the ampules in the carriage, due to the centering effect of the V-shaped cradles 57 and clips 6|. The clips grip the narrow section of the necks to hold them substantially concentric with the needles, while permitting the ampules easily to be removed from the carriage subsequently. While the narrow sections 8 of the necks of all ampules are centered in the clips, the positions of the bodies of the ampules in cradles 51 may vary in accordance with variations in the ampules.

Then the carriage is manually moved upward on the track 13 to its raised filling position illustrated in Fig. 3 determined by engagement of bridge member 5| with the stop G5. The carriage becomes releasably latched in this position by engagement of spring latch 13 with the detent H. This prevents the carriage from sliding downward if it should be released. As the carriage moves upward to its raised filling position, the ampules telescope over the needles without inter ference since the narrow sections of the necks are substantially concentric with the needles. With the carriage and ampules carried thereby in filling position, the needles extend completely through the necks of the ampules so that the clischarge ends of the needles are entered just within the cylindrical bodies of the ampules, with the discharge openings 1! above the level of the quantity of liquid that is to be supplied to the ampules. Then the dispensing pump (not shown) is operated to supply a measured quantity of liquid to each of the ampules. The liquid is delivered into the bodies of the ampules through the discharge openings at the lower ends of the needles below the lower ends of the necks, so that no liquid runs down through the necks.

When the filling of the ampules has been completeol, the carriage is moved downward to its lower retracted position. Should any liquid be present at the discharge opening of the ampule filling needles, it is notwiped onto the necks, inasmuch as the ends of the needles do not come into engagement with the insides of the necks. This is because of the assurance of substantial concentricity of the narrow sections of the necks and the needles. Once the carriage has been moved downward to its lower retracted position, the filled ampules'are removed from the carriage. They may then be placed in a machine for fiamesealing the necks, and two more ampules filled, and so on.

In view of the above, it will be seen that the several objects of the invention are achieved and other advantageous results attained.

As many changes could be made in the above constructions without departing from the scope of the invention, it is intended that all matter contained in the above description or shown in the accompanying drawings shall be interpreted as illustrative and not in a limiting sense.

We claim:

1. A device for use in filling ampules of the type comprising a cylindrical body and a neck having an intermediate narrow section, comprising an inclined track, an open-ended cylinder mounted at the upper end of the track with its axis substantially parallel to and above the track, a sleeve held in the cylinder by two axially spaced sets of adjustable three-point mountings with the axis of the sleeve substantially parallel to the track, an ampule filling needle held in the sleeve and extending downward in cantilever fashion above and generally parallel to the track, a carriage slidable on the track having a cradle for cradling the cylindrical body of an ampule and a member for supporting the neck of an ampule by its intermediate narrow section with the neck extending upward and with the narrow section of the neck substantially concentric with the needle, said carriage being slidable between a lower retracted position wherein an ampule may be placed therein, and a raised filling position, determined by engagement of the carriage with a stop on the track, wherein the needle extends completely through the neck of an ampule with the lower end of the needle entered in the body of the ampule.

2. The device set forth in claim 1, wherein the neck-supporting member comprises a spring clip.

3. The deviceset forth in claim 1, further including latch means for releasably latching the carriage in filling position.

4. A device for use in filling ampules of the type comprising a cylindrical body and a, neck having an intermediate narrow section, comprising an inclined track of V-shape in cross section with the V opening upward, an ampule filling needle mounted at the upper end of the track extending downward in cantilever fashion above and generally parallel to the track and generally in the vertical plane of the apex of the V, the needle having a discharge opening at its lower end, a carriage comprising a V-shaped cradle for cradling the cylindrical body of an ampule, the cradle being slidable in the V-shaped track, said cradle carrying a member for supporting the neck of an ampule by its intermediate narrow section with the neck extending upward and with the narrow section of the neck substantially concentric with the needle, said carriage being slidable between a lower retracted position wherein an ampule may be placed therein, and a raised filling position, determined by engagement of the carriage with a stop on the track, wherein the needle extends completely through the neck of the ampule with the lower end of the needle entered in the body of the ampule.

5. The device set forth in claim 4, wherein the neck-supporting member comprises a spring clip.

6. The device set forth in claim 4, further including latch means for releasably latching the carriage in filling position.

7. A device for use in filling ampules of the type comprising a cylindrical body and a neck having an intermediate narrow section, comprising an inclined track, a support at the upper end of the track, an ampule filling needle mounted in said support extending downward in cantilever fashion above and generally parallel to the track, means carried by the support holding the needle by its upper end in the support and adjustable with respect to the support for universal adjustment of the position of the axis of the needle, the needle having a discharge opening at its lower end, a carriage slidable on the track having a cradle for cradling the cylindrical body of an ampule and a member for gripping the neck of an ampule by its intermediate narrow section with the neck extending upward and with the narrow section of the neck substantially concentrio with the needle, said carriage being slidable between a lower retracted position wherein an ampule may be placed therein, and a raised filling position, determined by engagement of the carriage with a stop on the track, wherein the needle extends completely through the neck of the ampule with the lower end of the needle entered in the body of the ampule.

8. The device set forth in claim '7, wherein the neck-gripping member comprises a spring clip.

9. The device set forth in claim 8, further including latch means for releasably latching the carriage in filling position,

References Cited in the file of this patent UNITED STATES PATENTS Number Name Date 938,578 Gull Nov. 2, 1909 2,530,230 Cozzoli Nov. 14, 1950 FOREIGN PATENTS Number Country Date 566,937 Great Britain Jan. 19, 1945

US2687838A 1951-01-29 1951-01-29 Ampoule filling device Expired - Lifetime US2687838A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US2687838A US2687838A (en) 1951-01-29 1951-01-29 Ampoule filling device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2687838A US2687838A (en) 1951-01-29 1951-01-29 Ampoule filling device

Publications (1)

Publication Number Publication Date
US2687838A true US2687838A (en) 1954-08-31

Family

ID=22774549

Family Applications (1)

Application Number Title Priority Date Filing Date
US2687838A Expired - Lifetime US2687838A (en) 1951-01-29 1951-01-29 Ampoule filling device

Country Status (1)

Country Link
US (1) US2687838A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494087A (en) * 1994-10-13 1996-02-27 Pitelka; Karen J. Apparatus for aiding in the preparation of an injection serum

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US938578A (en) * 1907-04-15 1909-11-02 Rudolf Gull Machine for bottling beer.
GB566937A (en) * 1943-07-15 1945-01-19 Colby Engineering Company Ltd Improvements relating to machines for charging receptacles with liquid or solid substances
US2530230A (en) * 1948-07-24 1950-11-14 Frank J Cozzoli Combined filling and sealing machine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US938578A (en) * 1907-04-15 1909-11-02 Rudolf Gull Machine for bottling beer.
GB566937A (en) * 1943-07-15 1945-01-19 Colby Engineering Company Ltd Improvements relating to machines for charging receptacles with liquid or solid substances
US2530230A (en) * 1948-07-24 1950-11-14 Frank J Cozzoli Combined filling and sealing machine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494087A (en) * 1994-10-13 1996-02-27 Pitelka; Karen J. Apparatus for aiding in the preparation of an injection serum

Similar Documents

Publication Publication Date Title
US3552212A (en) Device for cleaning the exterior of an elongated body
US1847954A (en) Colon irrigator
US3833030A (en) Device for withdrawing or adding fluids to hypodermic syringes
US2000866A (en) Chassis checking gauge
US1479451A (en) Fluid-administering device
US3687175A (en) Apparatus for filling thin tubular containers with a liquid
US2300288A (en) Torque measuring machine
US3661189A (en) Liquid dispenser
US2150760A (en) Ampoule filler
US3460789A (en) Container suspension device
US2423784A (en) Sugar container and dispenser
US3955682A (en) Laboratory shelf for funnel-shaped glassware
US2413438A (en) Reversible nozzle for shipping containers
JPS5973753A (en) Ultra-minute amount spectrophotometer
US3184122A (en) Semi-automatic dilution pipette
US643102A (en) Sacking and weighing machine.
US2253954A (en) Lens blocking device
US3248120A (en) Adjustable tube holder
US2530230A (en) Combined filling and sealing machine
US2412954A (en) Coating device
US2353813A (en) Gauging apparatus
US4512203A (en) Liquid sampling device
US3212620A (en) Method and apparatus for feeding tubular articles into a work holder
US2358982A (en) Adjustable mounting for liquid fuel burners
US494467A (en) Liquid measurer and extractor