US2675802A - Injection device - Google Patents

Injection device Download PDF

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US2675802A
US2675802A US201588A US20158850A US2675802A US 2675802 A US2675802 A US 2675802A US 201588 A US201588 A US 201588A US 20158850 A US20158850 A US 20158850A US 2675802 A US2675802 A US 2675802A
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plunger
medicament
accumulator
bore
piston
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Jr George N Hein
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/30Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Definitions

  • This invention relates to a structurally and functionally improved hypodermic injection device and especially an apparatus by means of which medicament may be injected without the use of a skin-piercing needle.
  • an assembly which causes an expulsion of medicament at velocities and pressures and in a sufficiently fine stream such that skin penetration is eiected.
  • Apparatus of this type has been powered under ordinary circumstances by a power accumulator including a spring assembly or gas pressure. As the working stroke has occurred the expulsion force has diminished; this being as a consequence of the drop in pressure of the gas source or the decrease in force generated by the spring assembly as the latter has been expanded.
  • a power accumulator including a spring assembly or gas pressure.
  • the expulsion force has diminished; this being as a consequence of the drop in pressure of the gas source or the decrease in force generated by the spring assembly as the latter has been expanded.
  • Fig. 1 is a sectional side View of an injection apparatus and showing the parts of the mechanism in one position;
  • Fig. 3 is an enlarged fragmentary sectional view showing an alternative arrangement of structure different from that illustrated in Figs. 1 and 2.
  • the numeral 5 indicates a tubular body which adjacent its forward end may support a unit 5 dening a medicament chamber. Such support is conveniently achieved by screw threads. Likewise by means of screw threads a loading cap 'l is attached to unit 6. This loading cap is provided with a forward opening through which a nozzle member 8 projects. The outer end of this nozzle defines a relatively minute tone tone of such reduced diameter that medicament may be expelled therefrom in a suii'iciently fine stream to achieve the desired results.
  • Nozzle 8 has its rear or base end flanged as at 9 so as to be retained by cap 1. It may also be coupled to the member defining the medicament chamber proper. Such coupling is conveniently effected by forming the rearmost portion of nozzle 8 lwith a recess into which the flange I0 of a flexible cup II extends. That cup has a capacity equal to the injection which is to be made. As shown it is tapered towards its base end. Beyond that base it may be continued in the form of an integral extension I2. As is apparent unit 6 is formed with a recess having surfaces conforming to the surfaces of cup II. Also it is formed with a rearwardly extending bore within which plug I2 may move. In order to avoid unnecessary complications oi the drawings, the present apparatus has been illustrated as providing merely for a single injection after which it requires reloading.
  • the numeral I3 indicates va spring embodying force adequate to achieve the desired expulsion of medicament.
  • This spring will be pretensioned but be capable of further compression. Therefore adequate force will be available throughout the working stroke.
  • the spring is confined within a tube I4 reciprocable within body 5. Adjacent its forward end tube I4 mounts a cap I5 provided with a stem I6. The latter is disposed in line with and is of sufficiently small diameter that it enters the bore of unit 6. Accordingly, its forward end will engage the rear end of plug I2 of the medicament-containing sack or cup.
  • tube I4 Secured to the rear end of tube I4 is an assembly preferably including as shown a body Il formed with a bore I8.
  • the stem I9 of a supporting member 20 projects into this bore and ently adjacent the rear end of bore I 8 earlier'application is conveniently formed with a filling passage 2l normally maintained in closed position by a screw or other obstruction 22.
  • Support 20 bears against the rear end of spring I3 and is slidable Within the bore of tube I 4.
  • a ring packing 23 may be disposed within a recess formed in communication with the bore of body I1 and to bear against the surfaces of stem I 9.
  • Bore I3 is interrupted by a centrally apertured partition 24.
  • a piston slidably projects into the rear end of the bore and has been identified by the numeral 25.
  • This piston is conveniently formed with an extension or key 25 riding within a groove or keyway 21 forming a part of sleeve 28. The latter is attached by threads or in any other suitable manner to body I1.
  • a washer or spacing member 29 may be interposed between the abutting surfaces of body I1 and tube 28. Conveniand within that portion which provides a cylinder for piston 25 a further recess may be furnished for the reception of an O or ring shaped packing 30. A turning of tube 28 is prevented in any desired manner.
  • it may be formed with a longitudinally extending groove or keyway 3
  • piston 25 will likewise be prevented from rotating incident to the connection existing between these parts and indicated by the numerals 26 and 21.
  • an end cap 33 is mounted at the rear end of body 5.
  • This cap is formed with a central aperture which is threaded. Extending through the aperture and engaging these threads is a shaft 35.
  • the forward end of the shaft extends into a threaded recess 35 formed in the rear face of piston 25.
  • the threads in recess 35 and cap 33 are opposed.
  • the corresponding threads on shaft 34 are likewise opposed. Therefore when this shaft is turned it will not alone rotate with respect to the parts which it contacts but will also have axial movements with respect to those parts. To secure such turning Vany desired mechanism will be employed.
  • a crank 36 has been shown as mounted upon the squared rear end of shaft 34.
  • a triggering or release mechanism is conveniently provided by forming tube 28 with a recess into which the projecting end portion of a detent 31 extends.
  • the latter may be slidably mounted by a threaded thimble 3B and is spring pressed asv Vat $9. Its stem di! extends beyond the thimble and'pivotally mounts a cam member 4I.
  • the latter is provided with an extension 42.
  • a nut 3 Vis mounted upon the threads of thimble 38', and bears against a washer which, in turn, bears against the face of a slotted guide 44 disposed in .an inclined plane and secured against movement with respect to body by screws.
  • the bore I8 is filled with a suitable duid. This may take the formkof grease.
  • the fluid or body of material completely fills the forward portion of bore I8 when the parts are in the position shown in Fig. 1 and extends through the aperture in partition 24 into the rear portion of the bore in advance of piston 25. Its escape past piston 25 or between the surfaces of the bore and stem I9 is prevented by packings 23 and 3B. These will be especially effective if they are of the ring or other suitable type and having in mind that the spring I 3 is pre-loaded. Accordingly, pressure will always exist against these packings to prevent an escape of the material -or fluid.
  • the forward end of piston 25 carries a metering rod 43 which extends through the aperture of partition 24 into the forward portion of bore I8. For purposes of illustration the clearances and conguration of the parts has been somewhat exaggerated.
  • this rod has a diameter adjacent its base slightly less than the diameter of the aperture in partition 24. This diameter remains constant as in Figs. 1 and 2 for a distance such that the rod is not reduced until a point well beyond the partition is reached. At that point it extends in these gures in the form of a gradual tapered surface through to the rod end.
  • a body of grease has been indicated as extending at 44. The importance of this body has been somewhat exaggerated for purposes of illustration. It will be apparent that minute quantities of grease or equivalent material might be vented through the packing in which case they will serve as a lubricant.
  • plug I2 As the stem I5 moves forwardly it will push plug I2 in a similar direction.
  • the diameter of that plug is substantially equal to the base dia-meter of the cup bore.
  • the body of cup II being made of rubber or similar flexible material it therefore follows that the base of the cup will be projected within the bore of the latter. This will cause the side walls of the cup to invert upon themselves as shown in Fig. 2 thereby expelling substantially all liquid within the medica-ment chamber.
  • plug I2 advances and expands radially thereby preventing rearward distention of the walls of cup II as shown in Fig. 2.
  • the metering rod 43 is shifting to a position at which its tapered surfaces are passing through the aperture of the partition. Under these circumstances, constantly increasing clearances are presented. Therefore, the material or grease may flow with diminishing restraint from the forward portion of bore I8 to the rear portion of the latter. It will be apparent that by properly proportioning the taper of the metering rod, employing a suiciently stiff or fluid material, etc. the injection pressure might be maintained constant throughout the entire working stroke.
  • the metering rod might be proportioned as in Fig. 3. -In that view such rod includes a base portion l5 of substantially constant diameter, an adjacent reduced portion it and a tapered end portion lil. Again the clearancebetween the parts has been somewhat exaggerated. However, if the triggering mechanism is released and the assembly includes a metering rod of this type, it will be again apparent that the initial movement will not be so violent as to cause a sudden acceleration accompanied by an incidental noise. Rather that initial movement will merely result in the parts shifting so that the reduced portion 45 will enter the aperture of the partition. As will be understood, this will permit for the moment a substantially unrestrained flow of the grease, fluid or other material through the aperture of the partition. Therefore, the full force of spring i3 will thereafter act for a brief instant to expel medicament from the cup II.
  • the velocity of discharge of the medicament will be at a maximum rate.
  • This may serve, for example, to pierce a relatively resistant epidermis. Having eected this piercing by the jet or medicament, pressures may thereupon be reduced. Such reduction will occur as the tapered portion enters the aperture.
  • these tapered surfaces will serve to maintain a substantially constant pressure thro-ughout the remainder of the expulsion stroke. It is apparent, by suitably configuring the rod or other equivalent structure, that virtually any desired type of working stroke will result.
  • a hypodermic injection device comprising a body formed with a medicament chamber having a discharge opening, a source of motive power slidably mounted within said body to expel medicament from said chamber, means within said body to provide connected and otherwise closed compartments from one of which flowable material is transferred to the other, relatively movable means acting against and shifting material from one compartment to the other, means responsive to such shift to potentialize the source of motive power to expel medicament, releasable latch means for normally preventing an expulsion of medicament, metering means movable with respect to said compartments and extending into the connection between the same for controlling the flow of material from one to the other compartment and said metering means presenting a passage which is adjustable in area and being connected to shift with said power source.
  • An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator', manually operable leverage means movably mounted by said body and coupled to said accumulator for compressing the same, means forming a part of said device providing spaces and a passage for fluid flow as said plunger projects and valve means automatically regulating the speed of such flow as said plunger projects to control the movement of said plunger.
  • An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, manually operable leverage means movably mounted by said body and coupled to said accumulator for compressing the same, means forming a part of said device providing spaces and a passage for fluid ow as said plunger projects and variable metering means automatically regulating thespeed of such flow through said passage and from one space to the other as said plunger projects to thereby control the movement of said plunger.
  • An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed Within said body and connected to said plunger to project the latter upon expansion of said accumulator, manually operable leverage means movably mounted by said body and operatively coupled to said accumulator for compressing the same, said plunger assembly including spaces connected by a passage through which fluid ilovvs from one space to the other as said plunger projects and valve means mounted by said body and cooperative with said passage to regulate the speed of iiuid 110W therethrough and thereby control the movement of said plunger as the latter projects.
  • An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted bysaid body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed Within said body and connected to said plunger to project the latter upon expansion of said accumulator, manually operable leverage means movablymounted by said body and operatively coupled to said accumulator for compressing the same, said plunger assembly including spaces connected by a passage through vvhich iiuid ilovvs from one space to the other as said plunger projects, valve means extending into said passage to automatically regulate the speed of iiuid flow therethrough as said plunger projects to thereby control the movement of the latter and means connecting vsaid valve means with said leverage means to shift in response to the movement of the latter.
  • An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicamenttherefrom,v a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, said assembly providing a space to receive fluid material, manually operableleverage means movably mounted by said body, a piston shifted by said leverage means and acting against the material in said space to displace the same, means shifted by such displacement to compress said accumulator to potentialize said plunger for projection, releasable means for preventing such projection and metering means connected to saidA Y piston and cooperating' with the fluid material to govern the now thereof after the release of said means and during plunger projection.
  • An injection device including in combination a body, meansadjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible Vpressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, said assembly providing a space to receive fluid material, manually operable leverage means movably mounted by said body, a piston shifted by said leverage means and acting against the material in said space to displace the same, means shifted by such displacement to compress said accumulator to potentialize said plunger for projection, releasable means for preventing such projection, such space providing a restricted portion intermediate its ends and valve means connected to said piston and extending to a point adjacent said restricted portion to govern the rlow of fluid material through said space after release of said preventing means and during plunger projection.
  • An injection device including in combination a body, means adjacent one end of lsaid body dening a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, said assembly providing a space to receive iiuid material, manually operable leverage means movably mounted by said body, a piston shifted by said leverage means and acting against the material in said space to displace the same, means shifted by such displacement to compress said accumulator to potentialize said plunger for projection, releasable means for preventing such projection, such space providing a restricted portion intermediate its ends, valve means connected to said piston and extending to a point adjacent said restricted portion to govern the iiovv of fluid material through said space-after release of said preventing means and during plunger projection and said valve means presenting variable surfaces between which and said restricted portion said ilovv of fluid material

Description

April 20, 1954 G. N. HEIN, JR
INJECTION DEVICE File'd Dec. 19, 195o Patented Apr. 20, 1954 UNITED STATES PATENT OFFICE INJECTION DEVICE George N. Hein, Jr., San Carlos, Calif. Application December 19, 1950, Serial No. 201,588
This invention relates to a structurally and functionally improved hypodermic injection device and especially an apparatus by means of which medicament may be injected without the use of a skin-piercing needle.
Viewed in one aspect it is a primary object of the invention to furnish a structure embodying improved results over that disclosed in my prior application, Serial Number 113,598 led on September 1, 1949, and identied as Hypodermic Injection Apparatus.
By means of the present invention an assembly is provided which causes an expulsion of medicament at velocities and pressures and in a sufficiently fine stream such that skin penetration is eiected. Apparatus of this type has been powered under ordinary circumstances by a power accumulator including a spring assembly or gas pressure. As the working stroke has occurred the expulsion force has diminished; this being as a consequence of the drop in pressure of the gas source or the decrease in force generated by the spring assembly as the latter has been expanded. By means of the present teachings it is feasible to maintain the discharge pressures substantially constant throughout the entire working stroke. Accordingly, difficulties are not experienced as a consequence of the generation of high initial pressures and substantially diminished pressures towards the nal stages of the expulsion stroke.
Further by means of the'present teachings it Will be possible to cause the generation of virtually any desired expulsion pressure at any stage of the stroke. Therefore, it becomes feasible to discharge the apparatus without the existence of a high initial potential. Accordingly, a physician or other user is not confronted with the psychological objection of firing the apparatus with a simultaneous noise occurring incident to the release of high pressure and which noise is liable to cause the patient to iiinch.
Among other objects of the invention are those of providing an assembly including relatively few parts each individually simple and rugged in construction, such parts being capable of ready assemblage to furnish a compact and comparatively light weight apparatus functioning over long periods of time with freedom from all difficulties.
With these and other objects in mind reference is had to the attached sheet of drawings illustrating practical embodiments of the invention and in which:
Fig. 1 is a sectional side View of an injection apparatus and showing the parts of the mechanism in one position;
8 Claims. (Cl. 12S-1713) ig. 2 is a view similar to Fig. 1 but showing these parts in a different position; and
Fig. 3 is an enlarged fragmentary sectional view showing an alternative arrangement of structure different from that illustrated in Figs. 1 and 2.
In these views the numeral 5 indicates a tubular body which adjacent its forward end may support a unit 5 dening a medicament chamber. Such support is conveniently achieved by screw threads. Likewise by means of screw threads a loading cap 'l is attached to unit 6. This loading cap is provided with a forward opening through which a nozzle member 8 projects. The outer end of this nozzle defines a relatively minute orice of such reduced diameter that medicament may be expelled therefrom in a suii'iciently fine stream to achieve the desired results.
Nozzle 8 has its rear or base end flanged as at 9 so as to be retained by cap 1. It may also be coupled to the member defining the medicament chamber proper. Such coupling is conveniently effected by forming the rearmost portion of nozzle 8 lwith a recess into which the flange I0 of a flexible cup II extends. That cup has a capacity equal to the injection which is to be made. As shown it is tapered towards its base end. Beyond that base it may be continued in the form of an integral extension I2. As is apparent unit 6 is formed with a recess having surfaces conforming to the surfaces of cup II. Also it is formed with a rearwardly extending bore within which plug I2 may move. In order to avoid unnecessary complications oi the drawings, the present apparatus has been illustrated as providing merely for a single injection after which it requires reloading.
Thus the numeral I3 indicates va spring embodying force adequate to achieve the desired expulsion of medicament. This spring will be pretensioned but be capable of further compression. Therefore adequate force will be available throughout the working stroke. The spring is confined within a tube I4 reciprocable within body 5. Adjacent its forward end tube I4 mounts a cap I5 provided with a stem I6. The latter is disposed in line with and is of sufficiently small diameter that it enters the bore of unit 6. Accordingly, its forward end will engage the rear end of plug I2 of the medicament-containing sack or cup.
Secured to the rear end of tube I4 is an assembly preferably including as shown a body Il formed with a bore I8. The stem I9 of a supporting member 20 projects into this bore and ently adjacent the rear end of bore I 8 earlier'application is conveniently formed with a filling passage 2l normally maintained in closed position by a screw or other obstruction 22. Support 20 bears against the rear end of spring I3 and is slidable Within the bore of tube I 4. A ring packing 23 may be disposed within a recess formed in communication with the bore of body I1 and to bear against the surfaces of stem I 9.
Bore I3 is interrupted by a centrally apertured partition 24. A piston slidably projects into the rear end of the bore and has been identified by the numeral 25. In order to prevent this piston from turning it is conveniently formed with an extension or key 25 riding within a groove or keyway 21 forming a part of sleeve 28. The latter is attached by threads or in any other suitable manner to body I1. A washer or spacing member 29 may be interposed between the abutting surfaces of body I1 and tube 28. Conveniand within that portion which provides a cylinder for piston 25 a further recess may be furnished for the reception of an O or ring shaped packing 30. A turning of tube 28 is prevented in any desired manner. For example, it may be formed with a longitudinally extending groove or keyway 3| into which the end of a bolt 32 carried by body 5 may extend. Thus, it will be still capable of movement longitudinally of body 5. However, due to the fact that it is incapable of rotating, piston 25 will likewise be prevented from rotating incident to the connection existing between these parts and indicated by the numerals 26 and 21.
In order to provide a mechanism for shifting piston 25 and also to properly encase the parts an end cap 33 is mounted at the rear end of body 5. This cap is formed with a central aperture which is threaded. Extending through the aperture and engaging these threads is a shaft 35. The forward end of the shaft extends into a threaded recess 35 formed in the rear face of piston 25. As illustrated, the threads in recess 35 and cap 33 are opposed. The corresponding threads on shaft 34 are likewise opposed. Therefore when this shaft is turned it will not alone rotate with respect to the parts which it contacts but will also have axial movements with respect to those parts. To secure such turning Vany desired mechanism will be employed. For purposes of illustration a crank 36 has been shown as mounted upon the squared rear end of shaft 34.
A triggering or release mechanism is conveniently provided by forming tube 28 with a recess into which the projecting end portion of a detent 31 extends. The latter may be slidably mounted by a threaded thimble 3B and is spring pressed asv Vat $9. Its stem di! extends beyond the thimble and'pivotally mounts a cam member 4I. The latter is provided with an extension 42. A nut 3 Vis mounted upon the threads of thimble 38', and bears against a washer which, in turn, bears against the face of a slotted guide 44 disposed in .an inclined plane and secured against movement with respect to body by screws. The upper face of guide d'is conveniently'provided with graduations withwhich a suitable projecting part of the triggering mechanism may be aligned. This will bein accordance with the disclosure in the heretofore referred to and will permit of fractional dosages being injected according to the initial position of the triggering mechanism.. Y
Finally, as shown, the bore I8 is filled with a suitable duid. This may take the formkof grease.
The fluid or body of material completely fills the forward portion of bore I8 when the parts are in the position shown in Fig. 1 and extends through the aperture in partition 24 into the rear portion of the bore in advance of piston 25. Its escape past piston 25 or between the surfaces of the bore and stem I9 is prevented by packings 23 and 3B. These will be especially effective if they are of the ring or other suitable type and having in mind that the spring I 3 is pre-loaded. Accordingly, pressure will always exist against these packings to prevent an escape of the material -or fluid. The forward end of piston 25 carries a metering rod 43 which extends through the aperture of partition 24 into the forward portion of bore I8. For purposes of illustration the clearances and conguration of the parts has been somewhat exaggerated. However, this rod has a diameter adjacent its base slightly less than the diameter of the aperture in partition 24. This diameter remains constant as in Figs. 1 and 2 for a distance such that the rod is not reduced until a point well beyond the partition is reached. At that point it extends in these gures in the form of a gradual tapered surface through to the rod end. A body of grease has been indicated as extending at 44. The importance of this body has been somewhat exaggerated for purposes of illustration. It will be apparent that minute quantities of grease or equivalent material might be vented through the packing in which case they will serve as a lubricant.
In use it will be understood that an operator will turn shaft 34 to retract the entire assembly of movable parts to the left of body 5. This will be continued until detent 31 enters the recess formed in the surface of body 28 and under the inuence of spring 39 seats within that recess. At that position of the parts loading cap 1 may be removed and an assembly filled with medicament may be introduced into the recess and bore of body 6. Loading cap 1 is now remounted. Shaft 34 is now turned to secure a projection of piston 25. As that piston projects, it will displace the grease or other material through the apertureY assure twice the normal axial speed as would` otherwise occur. Y
If the outer end of nozzle 8 is now disposed adjacent the surface to'be injected and an operator depresses the release or trigger extension 42, injection will occur. This willbebecause cam 4I will retract stem spring 39 to therebywithdraw detent 31 from the recess in sleeve 28. Accordingly, while stein I9 and supporting portion or body 20 remain stationary those parts which are acted upon by the forward end of spring I3 are now released from restraint. Therefore, cap I5, together with stem IIS,v will be projected. In such projection it will carry with it tube I4 as well as body portion I1 and sleeve 28. Y This movement -of the parts will be permissible because tube I4 is freely slidable within body 5. Sleeve 28 Ehen-rotatable with Therefore spring 40 against the action of respect to tube I4 but may move longitudinally of body 5 because of keyway 3|. Likewise this sleeve may move longitudinally of piston 25 because of the key 2G and keyway 2.
As the stem I5 moves forwardly it will push plug I2 in a similar direction. The diameter of that plug is substantially equal to the base dia-meter of the cup bore. The body of cup II being made of rubber or similar flexible material it therefore follows that the base of the cup will be projected within the bore of the latter. This will cause the side walls of the cup to invert upon themselves as shown in Fig. 2 thereby expelling substantially all liquid within the medica-ment chamber. During the pressure stroke plug I2 advances and expands radially thereby preventing rearward distention of the walls of cup II as shown in Fig. 2.
The foregoing operation does not occur with unrestrained movements of the parts. Rather, it will be borne in mind that as detent 31 is withdrawn from the recess of tube 28, metering rod.
43 is in a position at which only a minimum passage of grease or controlling material may pass between its surfaces and the edges of the aperture formed in partition 2t. The restraining material must move from the forward end of bore I8 through the aperture into the cylinder portion occupied by piston 2b in order for the parts to move. Therefore, with minimum clearances, only relatively slow movement occurs. As a consequence of this slow movement the release of the detent from the recess in tubeZl is not accompanied by any appreciable noise such as occurs when the full shock of the expulsion force (usually more than 2,000 pounds per square inch) would be immediately released. Therefore, the action of spring I3 is restrained so that, for example, only the required pressure to effect penetration is transmitted to the uid medicament. Now as the force of the spring is released incident to its expansion, the metering rod 43 is shifting to a position at which its tapered surfaces are passing through the aperture of the partition. Under these circumstances, constantly increasing clearances are presented. Therefore, the material or grease may flow with diminishing restraint from the forward portion of bore I8 to the rear portion of the latter. It will be apparent that by properly proportioning the taper of the metering rod, employing a suiciently stiff or fluid material, etc. the injection pressure might be maintained constant throughout the entire working stroke.
Considering a fictitious or theoretical requirement, the metering rod might be proportioned as in Fig. 3. -In that view such rod includes a base portion l5 of substantially constant diameter, an adjacent reduced portion it and a tapered end portion lil. Again the clearancebetween the parts has been somewhat exaggerated. However, if the triggering mechanism is released and the assembly includes a metering rod of this type, it will be again apparent that the initial movement will not be so violent as to cause a sudden acceleration accompanied by an incidental noise. Rather that initial movement will merely result in the parts shifting so that the reduced portion 45 will enter the aperture of the partition. As will be understood, this will permit for the moment a substantially unrestrained flow of the grease, fluid or other material through the aperture of the partition. Therefore, the full force of spring i3 will thereafter act for a brief instant to expel medicament from the cup II.
Accordingly, the velocity of discharge of the medicament will be at a maximum rate. This may serve, for example, to pierce a relatively resistant epidermis. Having eected this piercing by the jet or medicament, pressures may thereupon be reduced. Such reduction will occur as the tapered portion enters the aperture. Thereupon, due to the fact that the metering rod 43 moves in synchronism with the shiftable assembly, these tapered surfaces will serve to maintain a substantially constant pressure thro-ughout the remainder of the expulsion stroke. It is apparent, by suitably configuring the rod or other equivalent structure, that virtually any desired type of working stroke will result.
Thus, among others, the several objects of the invention as specifically aforenoted are achieved. Obviously numerous changes in construction and rearrangement of the parts might be resorted to without departing from the spirit of the invention as defined by the claims.
I claim:
1. A hypodermic injection device comprising a body formed with a medicament chamber having a discharge opening, a source of motive power slidably mounted within said body to expel medicament from said chamber, means within said body to provide connected and otherwise closed compartments from one of which flowable material is transferred to the other, relatively movable means acting against and shifting material from one compartment to the other, means responsive to such shift to potentialize the source of motive power to expel medicament, releasable latch means for normally preventing an expulsion of medicament, metering means movable with respect to said compartments and extending into the connection between the same for controlling the flow of material from one to the other compartment and said metering means presenting a passage which is adjustable in area and being connected to shift with said power source.
2. An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator', manually operable leverage means movably mounted by said body and coupled to said accumulator for compressing the same, means forming a part of said device providing spaces and a passage for fluid flow as said plunger projects and valve means automatically regulating the speed of such flow as said plunger projects to control the movement of said plunger.
V3. An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, manually operable leverage means movably mounted by said body and coupled to said accumulator for compressing the same, means forming a part of said device providing spaces and a passage for fluid ow as said plunger projects and variable metering means automatically regulating thespeed of such flow through said passage and from one space to the other as said plunger projects to thereby control the movement of said plunger.
4. An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed Within said body and connected to said plunger to project the latter upon expansion of said accumulator, manually operable leverage means movably mounted by said body and operatively coupled to said accumulator for compressing the same, said plunger assembly including spaces connected by a passage through which fluid ilovvs from one space to the other as said plunger projects and valve means mounted by said body and cooperative with said passage to regulate the speed of iiuid 110W therethrough and thereby control the movement of said plunger as the latter projects.
5. An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted bysaid body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed Within said body and connected to said plunger to project the latter upon expansion of said accumulator, manually operable leverage means movablymounted by said body and operatively coupled to said accumulator for compressing the same, said plunger assembly including spaces connected by a passage through vvhich iiuid ilovvs from one space to the other as said plunger projects, valve means extending into said passage to automatically regulate the speed of iiuid flow therethrough as said plunger projects to thereby control the movement of the latter and means connecting vsaid valve means with said leverage means to shift in response to the movement of the latter.
6. An injection device including in combination a body, means adjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicamenttherefrom,v a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, said assembly providing a space to receive fluid material, manually operableleverage means movably mounted by said body, a piston shifted by said leverage means and acting against the material in said space to displace the same, means shifted by such displacement to compress said accumulator to potentialize said plunger for projection, releasable means for preventing such projection and metering means connected to saidA Y piston and cooperating' with the fluid material to govern the now thereof after the release of said means and during plunger projection.
7. An injection device including in combination a body, meansadjacent one end of said body defining a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible Vpressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, said assembly providing a space to receive fluid material, manually operable leverage means movably mounted by said body, a piston shifted by said leverage means and acting against the material in said space to displace the same, means shifted by such displacement to compress said accumulator to potentialize said plunger for projection, releasable means for preventing such projection, such space providing a restricted portion intermediate its ends and valve means connected to said piston and extending to a point adjacent said restricted portion to govern the rlow of fluid material through said space after release of said preventing means and during plunger projection.
8. An injection device including in combination a body, means adjacent one end of lsaid body dening a medicament-receiving chamber, a plunger assembly slidably mounted by said body and projectable towards said chamber for expelling medicament therefrom, a compressible pressure accumulator disposed within said body and connected to said plunger to project the latter upon expansion of said accumulator, said assembly providing a space to receive iiuid material, manually operable leverage means movably mounted by said body, a piston shifted by said leverage means and acting against the material in said space to displace the same, means shifted by such displacement to compress said accumulator to potentialize said plunger for projection, releasable means for preventing such projection, such space providing a restricted portion intermediate its ends, valve means connected to said piston and extending to a point adjacent said restricted portion to govern the iiovv of fluid material through said space-after release of said preventing means and during plunger projection and said valve means presenting variable surfaces between which and said restricted portion said ilovv of fluid material occurs.
References Cited in the le of this patent UNITED STATES PATENTS Number Name Date 2,295,849 Kayden Sept. 15, 1942 2,380,534 Lockhart July 31, 1945 2,397,051 vScherer Mar. 19, 1946 2,470,298 Fields May 17, 1949 2,505,763 Smoot Aug. 5, 1952
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202151A (en) * 1963-04-08 1965-08-24 Scherer Corp R P Multidose jet injector
US5080648A (en) * 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
US6056716A (en) * 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
EP1038542A1 (en) * 1999-03-24 2000-09-27 Deutscher Zahnarzt Verlag (DZV) Needleless injection device
US6309371B1 (en) 1998-07-27 2001-10-30 Medi-Jet Corporation Injection-assisting probe for medical injector assembly

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2295849A (en) * 1940-10-25 1942-09-15 Gustave L Kayden Attachment for hypodermic syringes
US2380534A (en) * 1941-04-26 1945-07-31 Marshall L Lockhart Hypodermic injector
US2397051A (en) * 1941-08-25 1946-03-19 Gelatin Products Corp Capsule
US2470298A (en) * 1949-02-07 1949-05-17 Abbott Lab Powdered medicine dispenser
US2605763A (en) * 1948-01-31 1952-08-05 Becton Dickinson Co Injection device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2295849A (en) * 1940-10-25 1942-09-15 Gustave L Kayden Attachment for hypodermic syringes
US2380534A (en) * 1941-04-26 1945-07-31 Marshall L Lockhart Hypodermic injector
US2397051A (en) * 1941-08-25 1946-03-19 Gelatin Products Corp Capsule
US2605763A (en) * 1948-01-31 1952-08-05 Becton Dickinson Co Injection device
US2470298A (en) * 1949-02-07 1949-05-17 Abbott Lab Powdered medicine dispenser

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202151A (en) * 1963-04-08 1965-08-24 Scherer Corp R P Multidose jet injector
US5080648A (en) * 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
US5318522A (en) * 1987-06-08 1994-06-07 Antonio Nicholas F D Hypodermic fluid dispenser
US6056716A (en) * 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
US6309371B1 (en) 1998-07-27 2001-10-30 Medi-Jet Corporation Injection-assisting probe for medical injector assembly
US20020058907A1 (en) * 1998-07-27 2002-05-16 Medi-Ject Corporation Injection-assisting probe for medical injector assembly
US7108675B2 (en) 1998-07-27 2006-09-19 Antares Pharma, Inc. Injection-assisting probe for medical injector assembly
EP1038542A1 (en) * 1999-03-24 2000-09-27 Deutscher Zahnarzt Verlag (DZV) Needleless injection device

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