US2594621A - Blood obtaining instrument - Google Patents

Blood obtaining instrument Download PDF

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Publication number
US2594621A
US2594621A US17739950A US2594621A US 2594621 A US2594621 A US 2594621A US 17739950 A US17739950 A US 17739950A US 2594621 A US2594621 A US 2594621A
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Grant
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Prior art keywords
receptacle
suction
needle
tube
blood
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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George W Derrick
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George W Derrick
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150213Venting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221Valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229Pumps for assisting the blood sampling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150267Modular design or construction, i.e. subunits are assembled separately before being joined together or the device comprises interchangeable or detachable modules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150351Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150473Double-ended needles, e.g. used with pre-evacuated sampling tubes
    • A61B5/150496Details of construction of hub, i.e. element used to attach the double-ended needle to a piercing device or sampling device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150732Needle holders, for instance for holding the needle by the hub, used for example with double-ended needle and pre-evacuated tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes

Description

April 29, 1952 G. w. DERRICK BLOOD OBTAINING INSTRUMENT Filed Aug. 5, 1950 INVENToR. GEORGE W. DERRICK ATTORNEY Patented Apr. 29, 1952 UNITED STATES PATENT ori-ICE 3 Claims.

This invention relates to a blood obtaining instrument by means of which a specimen of blood may be withdrawn from the body of a human being or of an animal and deposited into a receptacle which may thereafter be easily removed to a laboratory or other convenient place for an analysis of the blood specimen.

The main objects of this invention are to provide an instrument for obtaining blood specimens which is simple, durable and economical in construction, and wherein the parts thereof may be quickly and easily assembled or disassembled.

In carrying out the above mentioned objects 1 have provided a blood obtaining instrument which comprises a hypodermic needle, a glass receptacle for the blood specimen, and a simply constructed manually operated suction device for producing a partial vacuum in the glass receptacle.

Another object of the invention resides in providing an instrument of the character above referred to with a simple connecting means whereby the hypodermic needle and the suction device may be readily operatively connected to the glass receptacle, such connecting means being so constructed and arranged that the nee-Y dle and suction device may be removed from operative relation with the receptacle without momentarily subjecting the blood content thereof to outside atmospheric conditions, thereby eliminating possible contamination of the specimen.

Other objects and advantages of the instrument pertaining to its specic construction and to the form and relation of the parts thereof will more clearly appear from the following description taken in connection with the accompanying drawings in which:

Figure 1 is a longitudinal sectional view of the novel instrument made according to my invention, a portion thereof being shown in eleva-4 tion. i

Figure 2 is an elevation, partially in section, of a glass receptacle after it has been removed from the suction producing device.

Figure 3 illustrates the suction producing device in elevation detached from the glass receptacle, a portion thereof being broken away.

Figure 4 is a longitudinal sectional view similar to Figure l, illustrating a modied structure of my invention.

The instrument, as illustrated in Figures 1, 2, and 3, comprises a receptacle It and a suction device l I. The receptacle Ill is a tubular member having a closed bottom I2 and an open top I3, the same being made of glass or other suitable material, and preferably in the form of a test tube. The open top I3 of the receptacle I0 is closed by an end cap or stopper element I4 composed of relatively soft rubber or other suitable resilient material. The end cap i4 has a pair of axially disposed orices I5 and I3 extending inwardly from the top and bottom ends thereof respectively, and which are separated by a relatively narrow wall or partition I'I, as more clearly seen in Figure 2.

The suction device iI comprises an L-shaped header I9 having an L-shaped passage 20 extending therethrough. The shorter leg 2l of the header I9 is connected by a tube junction 22 to one end of a syringe bulb 23. The other or lower end of the bulb 23 has a valve structure 25 arranged to prevent entrance of air therethrough to the interior of the bulb 23 but permits the free exit of air from the interior of said bulb. The longer leg 25 of header I9 has an inwardly extending conical aperture 26 having communicationwith the adjacent end of passage 20. A ring-like support or head 23 is provided with a conical shaped projection or nipple 29 extending outwardly from one side thereof adapted to extend into the aperture 26 into functional engagement with the wall of said aperture.

A passage 30 in the projection 29 has its inner end communicating. with a suction tube 3l -mounted in the head 28 to project downwardly therefrom. The support or head 28 has` a substantially axially disposed conical bore 32 extending therethrough. A hypodermic needle 34 has a conical sleeve 35 mounted thereon which is adapted to extend into the bore 32 for frictionally connecting the needle with the head 28. The needle 34 and sleeve 35 may be secured together as by electric welding, brazing or the like. The lower ends of the suction tube 3l and needle 34 have needle points 34 and 3l respectively, which provide for the easy penetration of these members through the wall I'I of the cap I4. The receptacle I0, cap or stopper I4, needle 34, and suction tube 3I are thus held in connected relation with each other with an air-tight joint or seal between them.

When the suction device II, needle 34, and receptacle I9 are assembled as shown in Figure 1 the operator may cause the hypodermic needle to penetrate a blood vein from which it is desired to obtain a specimen. The syringe bulb 23 may now be collapsed, if this has not already been accomplished, to cause its air content to pass out through valved opening 25. Release of the bulb will now close valved opening 25 as the bulb returns to its normal form and cause air to be drawn from the interior of receptacle I0 out through tube 3I and passages 33 and 2) to the interior of the bulb 23, thus creating a reduction of the atmospheric pressure within the receptacle, thereby inducing a suction action in needle 34 which quickly withdraws blood from the vein. The blood `thus withdrawn ows through the needle 34 into the receptacle i0 and thus is deposited a specimen B within said receptacle.

After a specimen B is thus obtained, the receptacle and its stopper |4 are withdrawn from needle 34 and suction tube 3|. It will be understood that stopper |4 will remain in place on the receptacle I0 due to the greater surface contact thereof with the receptacle than with the needle and suction tube. As the needle 34 and suction tube 3| are thus removed from the stopper |4 the holes in the stopper produced by the needle and tube are immediately closed due to the inherent nature of the material composing the stopper. The closed receptacle I0, with its contents of blood specimen B, may now be removed to a convenient place for tests and examination. In the meantime the suction device and needle 34 may be assembled with a second receptacle I0 by the insertion of the needle 34 and suction tube 3| through the wall |1 of the stopper for the receptacle. It is thus seen that this instrument may be used over and over again for obtaining blood specimens in rapid succession which is particularly desirable in instances when making a multiplicity of blood tests as in recording the health condition of a ock of poultry or the like.

In the modied structure shown in Figure 4 the header as 38 has a cylindrical case 33, in lieu of syringe bulb 23, secured, as by screw threads 40, to the shorter leg 4| of header 38. The case 39 has a piston chamber 42 in which is reciprocally mounted a piston 43 having the rod 44 thereof extending downward through a suitable aperture in an end cap 45. The lower end of the piston rod 44 is xedly connected by an arm 46 to the lower end of a vertically disposed plunger 41 slidably mounted in a bore 48 provided in the cylinder case 39 in parallel spaced relation with piston chamber 42. The upper end of the bore 48 is closed by a nut 48 through which the plunger 41 extends and by which it is guided. The upper end of plunger 41 may, as shown, be provided with a nger piece 50. A spring 5| in the piston chamber 42 normally urges the piston 43 to its upper or innermost position. A valved passage 53 in piston 43 provides for the free passage of air from the inner end of the piston chamber to the outer end thereof as the piston moves inwardly. One or more vents 54 in cap 45 provide for the free passage of air from the lower end of the piston chamber 42 as the piston 43 is moved outwardly against the action of spring 5|.

The instrument shown in Figure 4 is used substantially the same as that illustrated in Figure l described above, with the exception that a minus pressure is produced in the receptacle |11 by exerting downward pressure on finger piece 50 and therefore piston 43 as is believed to be obvious.

Although I have shown and particularly described the preferred embodiment of my'invention and a modification thereof, I do not wish to be limited to the exact structure shown as it is obvious that other changes both in form and relation of the parts thereof may be readily made without departing from the spirit of the invention as set forth in the appended claims.

I claim:

1. A blood obtaining device, comprising, in combination, a fluid receptacle having an airtight stopper for effectively maintaining the interior of said fluid receptacle in a sterile condition, a suction device comprising a header having a passage extending therethrough connected to a source of vacuum, iluid conveying means including a suction tube operatively connecting the suction device with the receptacle in sterile relation to said interior of the receptacle, a surgical needle pointed at both ends, one end of said needle being disposed in the iiuid receptacle through the air-tight stopper and the other end adapted for direct insertion into the vein from which a blood sample is drawn, said stopper element having a needle and suction tube receiving portion so constructed and arranged that the receptacle may be disconnected from said needle and suction tube without breaking the fluid seal of said receptacle.

2. A blood obtaining device, comprising, in combination, a iiuid receptacle having an airtight stopper for effectively maintaining the interior of said fluid receptacle in a sterile condition, a suction device comprising a header having a passage extending therethrough connected to a source of vacuum, fluid conveying means including a suction tube operatively connecting the suction device with the receptacle in sterile relation to said interior of the receptacle, a surgical needle pointed at both ends, one end of said needle being disposed in the fluid receptacle through the air-tight stopper and the other end adapted for direct insertion into the vein from which a blood sample is drawn, said stopper element having a needle and suction tube receiving portion so constructed and arranged that the receptacle may be disconnected from said needle and suction tube without breaking the fluid seal of said receptacle, whereby the needle and said tube may simultaneously be inserted through the air-tight stopper.

3. A blood obtaining device, comprising, in combination, a fluid receptacle having an airtight stopper for effectively maintaining the interior of said fluid receptacle in a sterile condition, a suction device comprising a header having an L-shaped passage extending therethrough connected to a source of vacuum, fluid conveying means including a suction tube operatively connecting the suction device with the receptacle in sterile relation to said interior of the receptacle, a surgical needle pointed at both ends, one end of said needle being disposed in the fluid receptacle through the air-tight stopper and the other end adapted for direct insertion into the vein from which a blood sample is drawn, said stopper element having a needle and suction tube receiving portion so constructed and arranged that the receptacle may be disconnected from said needle and suction tube without breaking the iluid seal of said receptacle.

GEORGE W. DERRICK.

REFERENCES CITED The following references are of record in the le of this patent:

UNITED STATES PATENTS Number Name Date 2,231,564 Cooksey Feb. 11, 1941 2,460,641 Kleiner Feb. l, 1949 FOREIGN PATENTS Number Country Date 93,896 Sweden Sept. 1, 1938

US2594621A 1950-08-03 1950-08-03 Blood obtaining instrument Expired - Lifetime US2594621A (en)

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Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983037A (en) * 1973-11-05 1976-09-28 Jae Yoon Lee Apparatus for transfer, storage, and distribution of liquid
FR2322371A1 (en) * 1975-08-28 1977-03-25 Svensson Jan Method for evacuating a container and the samples taken and device for implementation of this method
US4073288A (en) * 1976-06-21 1978-02-14 Chapman Samuel L Blood sampling syringe
US4091802A (en) * 1976-02-17 1978-05-30 Eastman Kodak Company Vented liquid collection device
US4108175A (en) * 1977-01-28 1978-08-22 Orton Dale W Catheter insertion apparatus
US4192320A (en) * 1977-07-28 1980-03-11 Becton, Dickinson And Company Adapter for syringe
US4216782A (en) * 1977-02-15 1980-08-12 Sarstedt W Device for the extraction of blood
EP0017728A2 (en) * 1979-03-07 1980-10-29 C.A. Greiner & Söhne GmbH & Co. KG Blood letting instrument with blood sampling cannula and method of evacuating the cannula
US4392858A (en) * 1981-07-16 1983-07-12 Sherwood Medical Company Wound drainage device
US4404924A (en) * 1980-09-05 1983-09-20 Uresil Company Body fluid suction device indicators
EP0150127A2 (en) * 1984-01-24 1985-07-31 Bilbate Limited Suction generating device, particulary for fluid sampling
US4958622A (en) * 1983-05-11 1990-09-25 Selenke William M Hypodermic syringe for taking and transporting a specimen
US5071409A (en) * 1990-01-12 1991-12-10 Lior Rosenberg Vacuum device particularly useful for draining wounds
US5179960A (en) * 1991-08-16 1993-01-19 Helena Laboratories Corporation Biological fluid connection and delivery apparatus and method
US5195534A (en) * 1991-08-16 1993-03-23 Helena Laboratories Corporation Biological fluid collection and dispensing apparatus and method
US5653686A (en) * 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US5765591A (en) * 1995-11-20 1998-06-16 Argonaut Technologies, Inc. Valve apparatus and method for distributing fluids
US6395235B1 (en) 1998-08-21 2002-05-28 Argonaut Technologies, Inc. Devices and methods for accessing reaction vessels
US6706000B2 (en) 1997-11-21 2004-03-16 Amira Medical Methods and apparatus for expressing body fluid from an incision
US20040162506A1 (en) * 1996-05-17 2004-08-19 Duchon Brent G. Body fluid sampling device and methods of use
US20050277849A1 (en) * 2004-06-10 2005-12-15 Daniel Wong Vacuum sample expression device
US20070093728A1 (en) * 1996-05-17 2007-04-26 Douglas Joel S Blood and interstitial fluid sampling device
US20070293747A1 (en) * 1996-05-17 2007-12-20 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US20080149524A1 (en) * 2003-03-27 2008-06-26 Rademaker William B Food containers including dental cleaning devices and other personal care items
US20090118752A1 (en) * 2001-06-08 2009-05-07 Edward Perez Devices and methods for expression of bodily fluids from an incision
US20090308184A1 (en) * 2008-03-05 2009-12-17 Becton, Dickinson And Company Co-Molded Pierceable Stopper and Method for Making the Same
US7841991B2 (en) 1996-05-17 2010-11-30 Roche Diagnostics Operations, Inc. Methods and apparatus for expressing body fluid from an incision
US20110184312A1 (en) * 2008-08-14 2011-07-28 Moran Jr Antonio Bone Tissue Extracting Device and Method
US8460620B2 (en) 2010-12-03 2013-06-11 Becton, Dickinson And Company Specimen collection container assembly

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2231564A (en) * 1939-10-02 1941-02-11 Warren B Cooksey Blood transfusion apparatus
US2460641A (en) * 1945-08-14 1949-02-01 Joseph J Kleiner Blood collecting apparatus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2231564A (en) * 1939-10-02 1941-02-11 Warren B Cooksey Blood transfusion apparatus
US2460641A (en) * 1945-08-14 1949-02-01 Joseph J Kleiner Blood collecting apparatus

Cited By (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3983037A (en) * 1973-11-05 1976-09-28 Jae Yoon Lee Apparatus for transfer, storage, and distribution of liquid
FR2322371A1 (en) * 1975-08-28 1977-03-25 Svensson Jan Method for evacuating a container and the samples taken and device for implementation of this method
US4091802A (en) * 1976-02-17 1978-05-30 Eastman Kodak Company Vented liquid collection device
US4073288A (en) * 1976-06-21 1978-02-14 Chapman Samuel L Blood sampling syringe
US4108175A (en) * 1977-01-28 1978-08-22 Orton Dale W Catheter insertion apparatus
US4216782A (en) * 1977-02-15 1980-08-12 Sarstedt W Device for the extraction of blood
US4192320A (en) * 1977-07-28 1980-03-11 Becton, Dickinson And Company Adapter for syringe
EP0017728A3 (en) * 1979-03-07 1980-11-26 C.A. Greiner & Söhne GmbH & Co. KG Blood letting instrument with blood sampling cannula and method of evacuating the cannula
EP0045863A2 (en) * 1979-03-07 1982-02-17 C.A. Greiner & Söhne GmbH & Co. KG Blood sampling device
EP0045863A3 (en) * 1979-03-07 1982-05-26 C.A. Greiner & Söhne GmbH & Co. KG Blood sampling device
EP0017728A2 (en) * 1979-03-07 1980-10-29 C.A. Greiner & Söhne GmbH & Co. KG Blood letting instrument with blood sampling cannula and method of evacuating the cannula
US4404924A (en) * 1980-09-05 1983-09-20 Uresil Company Body fluid suction device indicators
US4392858A (en) * 1981-07-16 1983-07-12 Sherwood Medical Company Wound drainage device
US4958622A (en) * 1983-05-11 1990-09-25 Selenke William M Hypodermic syringe for taking and transporting a specimen
EP0150127A2 (en) * 1984-01-24 1985-07-31 Bilbate Limited Suction generating device, particulary for fluid sampling
EP0150127A3 (en) * 1984-01-24 1986-11-26 Bilbate Limited Suction generating device, particulary for fluid sampling
US5071409A (en) * 1990-01-12 1991-12-10 Lior Rosenberg Vacuum device particularly useful for draining wounds
US5179960A (en) * 1991-08-16 1993-01-19 Helena Laboratories Corporation Biological fluid connection and delivery apparatus and method
US5195534A (en) * 1991-08-16 1993-03-23 Helena Laboratories Corporation Biological fluid collection and dispensing apparatus and method
US5653686A (en) * 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US5765591A (en) * 1995-11-20 1998-06-16 Argonaut Technologies, Inc. Valve apparatus and method for distributing fluids
US5803105A (en) * 1995-11-20 1998-09-08 Argonaut Technologies, Inc. Systems and methods for distributing fluids
US20100222656A1 (en) * 1996-05-17 2010-09-02 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US8696596B2 (en) 1996-05-17 2014-04-15 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
US20040162506A1 (en) * 1996-05-17 2004-08-19 Duchon Brent G. Body fluid sampling device and methods of use
US8690798B2 (en) 1996-05-17 2014-04-08 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US7841991B2 (en) 1996-05-17 2010-11-30 Roche Diagnostics Operations, Inc. Methods and apparatus for expressing body fluid from an incision
US8231549B2 (en) 1996-05-17 2012-07-31 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US8740813B2 (en) 1996-05-17 2014-06-03 Roche Diagnostics Operations, Inc. Methods and apparatus for expressing body fluid from an incision
US20070293747A1 (en) * 1996-05-17 2007-12-20 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US20080015425A1 (en) * 1996-05-17 2008-01-17 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US8123701B2 (en) 1996-05-17 2012-02-28 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US7901363B2 (en) 1996-05-17 2011-03-08 Roche Diagnostics Operations, Inc. Body fluid sampling device and methods of use
US20110046515A1 (en) * 1996-05-17 2011-02-24 Douglas Joel S Methods and apparatus for expressing body fluid from an incision
US7828749B2 (en) 1996-05-17 2010-11-09 Roche Diagnostics Operations, Inc. Blood and interstitial fluid sampling device
US20100106058A1 (en) * 1996-05-17 2010-04-29 Douglas Joel S Blood and interstitial fluid sampling device
US7727168B2 (en) 1996-05-17 2010-06-01 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US7731668B2 (en) 1996-05-17 2010-06-08 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US20100222704A1 (en) * 1996-05-17 2010-09-02 Roche Diagnostics Operations, Inc. Methods and apparatus for sampling and analyzing body fluid
US20070093728A1 (en) * 1996-05-17 2007-04-26 Douglas Joel S Blood and interstitial fluid sampling device
US20060155316A1 (en) * 1997-11-21 2006-07-13 Roche Diagnostics Operations, Inc. Methods and apparatus for expressing body fluid from an incision
US20040204662A1 (en) * 1997-11-21 2004-10-14 Perez Edward P. Methods and apparatus for expressing body fluid from an incision
US6706000B2 (en) 1997-11-21 2004-03-16 Amira Medical Methods and apparatus for expressing body fluid from an incision
US6395235B1 (en) 1998-08-21 2002-05-28 Argonaut Technologies, Inc. Devices and methods for accessing reaction vessels
US9538941B2 (en) 2001-06-08 2017-01-10 Roche Diabetes Care, Inc. Devices and methods for expression of bodily fluids from an incision
US7758518B2 (en) 2001-06-08 2010-07-20 Roche Diagnostics Operations, Inc. Devices and methods for expression of bodily fluids from an incision
US20090118752A1 (en) * 2001-06-08 2009-05-07 Edward Perez Devices and methods for expression of bodily fluids from an incision
US20080149524A1 (en) * 2003-03-27 2008-06-26 Rademaker William B Food containers including dental cleaning devices and other personal care items
US20090131828A1 (en) * 2004-06-10 2009-05-21 Daniel Wong Vacuum sample expression device
US20050277849A1 (en) * 2004-06-10 2005-12-15 Daniel Wong Vacuum sample expression device
US20090308184A1 (en) * 2008-03-05 2009-12-17 Becton, Dickinson And Company Co-Molded Pierceable Stopper and Method for Making the Same
US8806920B2 (en) 2008-03-05 2014-08-19 Becton, Dickinson And Company Co-molded pierceable stopper and method for making the same
US8617085B2 (en) * 2008-08-14 2013-12-31 Antonio Moran, JR. Bone tissue extracting device and method
US20110184312A1 (en) * 2008-08-14 2011-07-28 Moran Jr Antonio Bone Tissue Extracting Device and Method
US9399218B2 (en) 2010-12-03 2016-07-26 Becton, Dickinson And Company Specimen collection container assembly
US9962704B2 (en) 2010-12-03 2018-05-08 Becton, Dickinson And Company Specimen collection container assembly
US8460620B2 (en) 2010-12-03 2013-06-11 Becton, Dickinson And Company Specimen collection container assembly

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