US2493155A - Apparatus for treating skin diseases - Google Patents

Apparatus for treating skin diseases Download PDF

Info

Publication number
US2493155A
US2493155A US72095447A US2493155A US 2493155 A US2493155 A US 2493155A US 72095447 A US72095447 A US 72095447A US 2493155 A US2493155 A US 2493155A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
cup
skin
electrode
adapted
circuit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Inventor
William R Mcmillan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSA Safety Inc
Original Assignee
MSA Safety Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/00051Accessories for dressings
    • A61F13/00063Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84Accessories, not otherwise provided for, for absorbent pads
    • A61F13/8405Additives, e.g. for odour, disinfectant or pH control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00902Plasters containing means
    • A61F2013/00919Plasters containing means for physical therapy, e.g. cold or magnetic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/15Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/84Accessories, not otherwise provided for, for absorbent pads
    • A61F2013/8476Accessories, not otherwise provided for, for absorbent pads with various devices or method

Description

Jan. 3, 1950 w. R. M MILLAN APPARATUS FOR TREATING SKIN DISEASES Filed Jan. 9, 1947 Patented Jan. 3, 1950 STATES PATENT 2,493,155.

APBARATUS'FORZIREATINGSKIN DISEASES William R. McMillan, Library,-.l?a.,,assignor. to.

Mine Safety Appliances Company, Pittsburgh,

Pa:, a corpcrationof Pennsylvania Applicationfianuary 9, 1947 ;:S'erialjNo'. 720954 (Cl. Rit -172.1

4 Claims.

This invention relates to the treatment of diseased .skin and tissue and, in particular, to apparatusfor electrically supplying a therapeutic agent: to thearea. to be;- treated.

It has. been found highly beneficial to treat various. forms of; skin or tissuev diseases, such-as epidermophytoses (athletesfoot) or other. moldy infections,;.b v iontophoresis of copper orother like-therapeutic agents. This may be accomr plished by the.electrolyticprocess, in which cop,- per ions from theelectrolyte migrate to. and-into the diseased. tissues when the circuit isclosed. Less common processes include electro -osmosis orelectro-phoresis, andare Within the contemplation of the present .invention.

Oneof thehandicaps-of these, treatments is the danger of. electrically shocking the patient. Toprevent this,- a circuit hasbeen devised which canbe controlled either manually; or automatic.- ally so as to .provide averysmall ilowof current when 7 initially closed and. to gradually;- increase the current to. provide eventually {a relatively large flow Without causing discomfort .toithe. pa tient. Sucha circuit is" disclosed in Conrad Patent No. 2,263,205, and it is my intention to utilize that circuit with the-improved treatment device disclosed herein. As shown in the Conrad patent, the diseased "or'affected part is immersedfin an electrolyte containing a therapeutic agent. The solution is carriedin areceptacle, such as a common. pan, and the hands also are immersed in another solution carried in a separate pan. When electrodes, which are placedinthe pan, are connectediwith a source of electromotive force, the body serves as a conductor to close the. circuit and permit-the flow ofelectriccurrent. When the affected partis' a foot or hand, the treatment can be performed satisfactorily. However, it would-be extremely inconvenient, if notimpossible, to so treat other portionsof the body, such for instance, as an infection of the face, neck or arm. Further; theConrad'systemuses a large body 'massras; a..-conductor" in the circuit so; that any sudden surgezof currentdue .togartaulty cirrcuit or careless circuit control might cause undue l sensory or motor discomfort. When the patients hands are immersed in a solution in one pan, another person may be required to manipulate the current controls.

It is among the objects of this invention to vertical. section taken,

copper: sulphate. solution, 1'.-

mobilizeE the hands; during treatment; .andlwhich requires electricity to. flowthrough no morelt'han a. veryshortpath-inthe body Accordingto theinventionthe edge. of a. cup is. pressed against. theskin. around the diseased area, preferably by astrapbrtape. The cup holds the. electricvv conducting fluid which con,-

tains .theftherapeuticagent that. is. to besupplied to the aiiected. area electrically. Electric. con.-

ductors;. closely associated with the cup, are adaptedto be connected into. an, electric circuit of the type disclosed: in .theConrad patent. Qne

of the. conductors; extends. into the solution. in the-,cup,=,while the other: is inelectric. contact withthe-skimoutside of. the cup. The current flows through the conductors, the. conducting fluid and the diseased. tissue area. to. cause the therapeutic agent to treat that-area.

The preferred embodiment of the inventioniis illustrated. in.v the accompanying,-. drawing, of which Fig, .1 .is aplan view of the. devicein oper- ,ative positionon a-patientfsarm; vFig. 2.is.a..ver.-

ticalsection through the device on thearmtaken on lineIL-II ofiFig. 1; andFig. S is anenlarged onthe, line lit-Ill; of Fig. 1. p

The following detailed description of. this -invention will. have-reference to .itsapplication in theaprocess .of electrolytically, treating, .skin diseasesmith a .:solution such .as. copp er.sulphate,..but it is notto-be-limited to that, particular solution. skinfwill be used broadly herein to include tissue.

is-vheldin liquid sealing engagement with the arm by.:*an ;.elastic. strap; 3. or by;- other'meanss such as a suitable: harness: or- 'adhesive' tape. The end wall of the 01113,,WhiCh-1Sfitfth8-t01? intheadrawing, ia provided with an opening; encircled by a neck 34:- inswhichthere; isaremovable stopper or plug 5; Bygremoving. .thaplug, the; cup: can. be filled; on the --arm..to:' the; desired extent with a The-plug; and the cup are constructed of any suitabe material, such as glass, plastic or rubber, which is electrically non-conductive and which is not attacked corrosively by the electrolyte.

The plug is provided with an axial passage in which a rod-like copper anode 8 is mounted. This electrode seals the plug passage and extends into the electrolyte in the cup. On the inner end of the electrode is mounted an insulating cap ID to prevent accidental contact of the electrode with the skin. A set screw 9 is mounted in the outer end of the electrode to connect it to a wire I I leading to a suitable source of electricity, preferably the circuit shown in the Conrad patent re ferred to above. Encircling the lip of the cup is a ring-shaped copper cathode l2, which is positioned close to it. This electrode also is provided with a set screw [3 for connecting it to a wire l4 leading to the same source of electricity or circuit as the other wire I I. In order to provide a good electrical connection between the annular electrode and the skin, a ring it of fabric, such as gauze, is moistened with a conducting liquid, for example, a salt solution, and is inserted between the electrode and the arm. The moist conductor I6 is pressed against the skin by the ring electrode 12 which in turn is pressed toward the skin by four arms I 7 these, preferably, being, leaf springs. The upper ends of these springs are fastened to the side wall of the cup by rivets l8, while their lower ends bear against the cathode.

The electrodes are connected into a controlled circuit, such as the Com'ad circuit previously mentioned. Anode 8 is connected to the positive side of the circuit and cathode E2 to the negative side. The current passing through the copper sulphate and the diseased area of the arm causes copper ions to migrate to and be deposited on and in the diseased skin. The use of this small device, which can be attached to localized areas of various parts of the body, makes it easy and comfortable to treat many areas that could not have been reached satisfactorily with the old system using pans. This device also leaves the hands free, and does not require electricity to flow through a large part of the body.

According to the provisions of the patent statutes, I have explained the principle, preferred embodiment and mode of operation of my invention, and have illustrated and described what I now consider to represent its best embodiment. However, I desire to have it understood that, within the scope of the appended claims, the invention may be practiced otherwise than as specifically illustrated and described.

I claim:

1. In apparatus for therapeutically treating skin diseases, a cup having its edge adapted to be pressed against the skin around the diseased area, said cup being adapted to hold against said area an electrically conductive liquid containing a therapeutic agent, an electrode mounted in the wall of the cup with its inner end adapted to extend into the liquid therein, an annular electric conductor surrounding the cup, and resilient means connected to the cup and adapted to press said conductor against the skin, said conductor and electrode being adapted to be connected to a source of electricity to form an electric circuit through said diseased area of the skin.

2. In apparatus for therapeutically treating skin diseases, a cup having its edge adapted to be pressed against the skin around the diseased area, said cup being adapted to hold against said area an electrically conductive liquid containing '3 4 therapeutic agent, an electrode mounted in the wall of the cup with its inner end adapted to extend into the liquid therein, an annular electrode surrounding the cup, an annular moist conductor engaging the annular electrode, leaf springs secured to the cup and engaging the annular electrode to press said moist conductor against the skin, said electrodes being adapted to be connected to a source of electricity to form an electric circuit through said diseased area of the skin.

3. In apparatus for therapeutically treating skin diseases, a cup having its edge adapted to engage the skin around the diseased area, adjust- :able means engaging the cup for pressing it against the skin in sealing engagement therewith, said cup being adapted to hold against said area an electrically conductive liquid containing a therapeutic agent, an electrode extending through the wall of the cup with its inner end adapted to be immersed in the liquid therein, an annular electric conductor surrounding the cup, and an arm having one end secured to the cup and the other bearing against and pressing said conductor against the skin, said electrode and conductor being adapted to be connected to a source of electricity to form an electric circuit through said dis eased area of the skin.

4. In apparatus for therapeutically treating skin diseases, a cup having its edge adapted to be pressed against the skin around the diseased area, said cup being provided with an opening through which it can be filled with an electrolyte containing a therapeutic agent, a, plug normally closing said opening and provided with a passage, an electrode extending through said passage and sealing it, the inner end of said electrode being adapted to project into the electrolyte in the cup, an electric conductor surrounding the cup, a spring connected to the cup and adapted to press said conductor against the skin, said conductor and electrode being adapted to be connected to a source of electricity to form an electric circuit through said diseased area.

WILLIAM R. McMILLAN.

REFERENCES CITED The following references are of record in the file of this patent:

UNITED STATES PATENTS Number Name Date 116,004 Amer June 20, 1871 309,897 Thurston Dec. 30, 1884 1,573,116 Kobayashi Feb. 16, 1926 2,126,070 Wappler Aug. 9, 1938 2,263,205 Conrad Nov. 18, 1941 FOREIGN PATENTS Number Country Date 498,527 Great Britain Jan. 10, 1939 OTHER REFERENCES Electrotherapy and Light Therapy, Richard K0- vacs, copyright 1945, pages 602-604. Note Figs. 335-337 and page 603, lines 4-48.

US2493155A 1947-01-09 1947-01-09 Apparatus for treating skin diseases Expired - Lifetime US2493155A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US2493155A US2493155A (en) 1947-01-09 1947-01-09 Apparatus for treating skin diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2493155A US2493155A (en) 1947-01-09 1947-01-09 Apparatus for treating skin diseases

Publications (1)

Publication Number Publication Date
US2493155A true US2493155A (en) 1950-01-03

Family

ID=24895927

Family Applications (1)

Application Number Title Priority Date Filing Date
US2493155A Expired - Lifetime US2493155A (en) 1947-01-09 1947-01-09 Apparatus for treating skin diseases

Country Status (1)

Country Link
US (1) US2493155A (en)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3187745A (en) * 1961-08-01 1965-06-08 Melpar Inc Electrodes
US3364929A (en) * 1964-12-21 1968-01-23 Burroughs Wellcome Co Method for administering muscle relaxant drug
US3387608A (en) * 1964-01-07 1968-06-11 Ceskoslovenska Akademie Ved Electrode for electromedical measurement
US3474775A (en) * 1967-02-27 1969-10-28 William R Johnson Electrode assembly for skin contact
US3580240A (en) * 1969-01-17 1971-05-25 Hoffmann La Roche Disposable electrode with self-sealing plug outlet
US3612061A (en) * 1969-02-20 1971-10-12 Inst Of Medical Sciences The Flexible cutaneous electrode matrix
US4376437A (en) * 1978-07-10 1983-03-15 Sundheim Benson R Topical environmental device
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
WO1986002277A1 (en) * 1984-10-12 1986-04-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4767401A (en) * 1975-04-22 1988-08-30 Maurice Seiderman Iontophoretic administration of ionizable or polar medicaments to a mammalian body
US4883457A (en) * 1983-08-18 1989-11-28 Drug Delivery Systems Inc. Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same
US5087240A (en) * 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US5135480A (en) * 1986-07-10 1992-08-04 Elan Transdermal Limited Transdermal drug delivery device
US5230703A (en) * 1992-04-09 1993-07-27 Staodyn, Inc. Wound infection resolution utilizing antibiotic agents and electrical stimulation
US5395398A (en) * 1993-07-28 1995-03-07 C. R. Bard, Inc. Microelectric apparatus for the antisepsis, promulgation of healing and analgesia of wound and chronic skin ulcers
US5840057A (en) * 1995-01-27 1998-11-24 Aloisi; Alessandro Device for iontophoretic physiotherapy with frozen medicament crystals
US20040116770A1 (en) * 2000-10-17 2004-06-17 O'connor Michael Controlled environment device
US20040143210A1 (en) * 2002-07-29 2004-07-22 Eemso, Inc. System and method for iontophoretic transdermal delivery of one or more therapeutic agents
US20090304776A1 (en) * 2008-06-06 2009-12-10 Totada Shantha Transmucosal delivery of therapeutic agents and methods of use thereof
US20090311311A1 (en) * 2008-06-16 2009-12-17 Shantha Totada R Transdermal local anesthetic patch with injection port
WO2011031116A2 (en) 2009-09-14 2011-03-17 Kim Hee Gu Pad for herbal medicine in which release of medicinal ingredient can be controlled, and manufacturing method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US116004A (en) * 1871-06-20 Improvement in attachments for vacuum-cups
US309897A (en) * 1884-12-30 Device foe
US1573116A (en) * 1924-09-02 1926-02-16 Kobayashi Tsurukichi Thermatologic electrode
US2126070A (en) * 1932-04-29 1938-08-09 Wappler Frederick Charles Electrotherapy
GB498527A (en) * 1937-07-16 1939-01-10 Scholl Mfg Co Ltd Improvements in and relating to applicator electrodes for electro-therapeutic purposes
US2263205A (en) * 1939-03-24 1941-11-18 Mine Safety Appliances Co Apparatus for the treatment of skin diseases

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US116004A (en) * 1871-06-20 Improvement in attachments for vacuum-cups
US309897A (en) * 1884-12-30 Device foe
US1573116A (en) * 1924-09-02 1926-02-16 Kobayashi Tsurukichi Thermatologic electrode
US2126070A (en) * 1932-04-29 1938-08-09 Wappler Frederick Charles Electrotherapy
GB498527A (en) * 1937-07-16 1939-01-10 Scholl Mfg Co Ltd Improvements in and relating to applicator electrodes for electro-therapeutic purposes
US2263205A (en) * 1939-03-24 1941-11-18 Mine Safety Appliances Co Apparatus for the treatment of skin diseases

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3187745A (en) * 1961-08-01 1965-06-08 Melpar Inc Electrodes
US3387608A (en) * 1964-01-07 1968-06-11 Ceskoslovenska Akademie Ved Electrode for electromedical measurement
US3364929A (en) * 1964-12-21 1968-01-23 Burroughs Wellcome Co Method for administering muscle relaxant drug
US3474775A (en) * 1967-02-27 1969-10-28 William R Johnson Electrode assembly for skin contact
US3580240A (en) * 1969-01-17 1971-05-25 Hoffmann La Roche Disposable electrode with self-sealing plug outlet
US3612061A (en) * 1969-02-20 1971-10-12 Inst Of Medical Sciences The Flexible cutaneous electrode matrix
US4767401A (en) * 1975-04-22 1988-08-30 Maurice Seiderman Iontophoretic administration of ionizable or polar medicaments to a mammalian body
US4376437A (en) * 1978-07-10 1983-03-15 Sundheim Benson R Topical environmental device
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US5087240A (en) * 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4883457A (en) * 1983-08-18 1989-11-28 Drug Delivery Systems Inc. Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same
WO1986002277A1 (en) * 1984-10-12 1986-04-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4713050A (en) * 1984-10-12 1987-12-15 Drug Delivery Systems Inc. Applicator for non-invasive transcutaneous delivery of medicament
US5135480A (en) * 1986-07-10 1992-08-04 Elan Transdermal Limited Transdermal drug delivery device
US5230703A (en) * 1992-04-09 1993-07-27 Staodyn, Inc. Wound infection resolution utilizing antibiotic agents and electrical stimulation
US5395398A (en) * 1993-07-28 1995-03-07 C. R. Bard, Inc. Microelectric apparatus for the antisepsis, promulgation of healing and analgesia of wound and chronic skin ulcers
US5840057A (en) * 1995-01-27 1998-11-24 Aloisi; Alessandro Device for iontophoretic physiotherapy with frozen medicament crystals
US7037254B2 (en) * 2000-10-17 2006-05-02 O'connor Michael Controlled environment device
US20040116770A1 (en) * 2000-10-17 2004-06-17 O'connor Michael Controlled environment device
US20040143210A1 (en) * 2002-07-29 2004-07-22 Eemso, Inc. System and method for iontophoretic transdermal delivery of one or more therapeutic agents
US20060009730A2 (en) * 2002-07-29 2006-01-12 Eemso, Inc. Iontophoretic Transdermal Delivery of One or More Therapeutic Agents
US20040225253A1 (en) * 2002-07-29 2004-11-11 Eemso, Inc., A Texas Corporation System and method for iontophoretic transdermal delivery of one or more therapeutic agents
US20090304776A1 (en) * 2008-06-06 2009-12-10 Totada Shantha Transmucosal delivery of therapeutic agents and methods of use thereof
US20090311311A1 (en) * 2008-06-16 2009-12-17 Shantha Totada R Transdermal local anesthetic patch with injection port
US7883487B2 (en) 2008-06-16 2011-02-08 Shantha Totada R Transdermal local anesthetic patch with injection port
WO2011031116A2 (en) 2009-09-14 2011-03-17 Kim Hee Gu Pad for herbal medicine in which release of medicinal ingredient can be controlled, and manufacturing method thereof

Similar Documents

Publication Publication Date Title
US3682162A (en) Combined electrode and hypodermic syringe needle
US3340868A (en) Body signal pickup electrode
US3490442A (en) Electrode with contact-forming suction cup means
US3405715A (en) Implantable electrode
US3367339A (en) Implantable nerve stimulating electrode and lead
US6522927B1 (en) Electrode assembly for a percutaneous electrical therapy system
US3866613A (en) Pessary ring electrode system
US5800498A (en) Catheter for implantable rhythm control device
US4211222A (en) Iontophoretic burn-protection method
US6633780B1 (en) Cardiac shock electrode system and corresponding implantable defibrillator system
US6134479A (en) Electrode triad for external defibrillation
US2043083A (en) Therapeutic electrode and plug therefor
US4310000A (en) Implantable pulse generator having separate passive sensing reference electrode
US6301502B1 (en) Defibrillation system
US3207161A (en) Ionization dental system
US20040167461A1 (en) Dermal patch
US5354321A (en) Patch arrangement for galvanic treatment
US5725563A (en) Electronic device and method for adrenergically stimulating the sympathetic system with respect to the venous media
US5534019A (en) Cardiac defibrillator with case that can be electrically active or inactive
US5070862A (en) Glove for electro-massage therapy
US4706688A (en) Non-invasive cardiac device
US6582416B2 (en) Iontophoretic treatment system
US2417530A (en) Electrical hair removing instrument
US3893461A (en) Pacing apparatus and method utilizing improved catheter
US20070150008A1 (en) Defibrillation electrode having drug delivery capablity