US2312488A - Coagulometer - Google Patents

Coagulometer Download PDF

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US2312488A
US2312488A US32415040A US2312488A US 2312488 A US2312488 A US 2312488A US 32415040 A US32415040 A US 32415040A US 2312488 A US2312488 A US 2312488A
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blood
film
opening
section
spot
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Robert L Rowland
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Robert L Rowland
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4905Determining clotting time of blood

Description

March 2, 1943.

R. 1.. ROWLAND COAGULOMETER Filed March 15, 1940 III I I 7////V SPOT IN VENTOR.

fiaerf Z. fiawfand XMA ATTORNEY Patented Mar. 2, 1943 UNITED STATES PATENT OFFICE COAGULOMETER Robert L. Rowland, Ogden, Utah Application March 15, 1940, Serial No. 324,150

6 Claims.

The present invention relates to the science of medicine and more particularly to an instrument for use by surgeons to determine the period of time required for the coagulation of the blood of a patient.

The instrument is especially useful in hospitals and in medical laboratories where various blood tests are being conducted.

The present invention and its use comprise providing a support having an opening therein of such size as to sustain a film of blood by surface tension, placing blood across the opening to form a film having a thin spot therein, oscillating the support on a substantially horizontal axis until the thin spot ceases to move and the blood film becomes immobile, and checking the time period from the procurement of the blood from the body of the patient to the moment when the film of blood ceases to be mobile.

An instrument comprising one form of device for carrying out the above specified method comprises a support provided with a small opening across which a film of blood may be stretched by surface tension. This support may comprise a washer having an opening therein or a wire loop of appropriate size carried by a main plate or ring of suitable material and of convenient size and shape for handling. Back and top plates are provided on each side of the main plate so as to enclose the film of blood in a substantially,

sealed chamber, thereby obviating excessive evaporation of the liquid content of the blood during the observation interval. Preferably, the back plate is of translucent material to pass diffused light or it may be adapted to refiect light, and the top is either provided with an opening or is transparent so that the condition of the specimen of blood film may be easily observed.

It is to be understood that the specific disclosures herewith are illustrative and are not to be considered in a limiting sense but comprise preferred embodiments of the present invention.

Fig. 1 is a plan view of one form of the apparatus showing the top and bottom plates moved aside in order to more clearly exhibit the same.

Fig. 2 is a section on line 2-2 of Fig. 1 with the cover plates closed.

Fig. 3 is a slightly different form of the invention mounted in a circular support.

Fig. 4 is an elevational view showing a section through the main plate of the device shown in Fig. 3.

Fig. 5 is an enlarged cross section of the supporting ring with a film of blood therein and shows the thin spot in the film.

Referring to the drawing and more especially to Figs. 1 and 2, the preferred form of the coagulometer comprises a main section I, a back plate 2, and a top plate 4. These three members may be oblong or rectangular in form and may be pivoted together by means of a pivot rivet or screw 5. The main section I is provided with an opening 6 in which is mounted a ring or loop of wire 1 having a substantially circular opening 8 comprising the test opening.

The sections I, 2, and 4 are preferably formed from synthetic resins, and may be constructed from a phenolic plastic resin known in the trade as Insurok. The middle section I preferably is black in color and may be of a thickness of substantially one-eighth of an inch. The back plate 2 is preferably translucent and of a milkwhite color and may be of a thickness of onesixteenth of an inch. The top plate 4 is preferably the same thickness as the back plate and preferably is transparent. The color scheme specified provides contrasting shades which are well suited to the observations necessary in the use of the device and the back plate 2 acts more or less like a ground glass to diffuse the light. The wire comprising the loop I is preferably of material which does not oxidize easily, such as stainless steel or other metal which is resistant to attack either from the air or from any blood content. The blood film opening 8 is preferably one-eighth of an inch in diameter. It is to be understood that the dimensions given herewith are not critical except that the blood film opening must be sufiiciently small to sustain a film of blood by its surface tension and sufiiciently large to produce the thin spot and to permit of proper observation of the suspended film.

In the use of the device, the back and front plates are moved aside to expose the opening 6 in the main section in which is mounted the loop of wire 1. A drop of blood is obtained from the patient in the usual manner, from a finger puncture or otherwise, and the instant of time of obtaining the blood sample is noted. This drop of blood is placed upon the wire ring 1 in such manner as to form a film which is suspended from the ring. The back and top plates are now brought into position as indicated in Fig. 2 over the main plate so that the space provided by the circular opening 6 in the middle section I is substantially sealed, thereby preventing undue evaporation of the blood sample. When the instrument is properly held between the thumb and finger in a substantially horizontal position, it will be observed that there is a thin spot in the center of the blood film stretched over the circular opening 1 in the loop of wire (see Fig. This thin spot is where the blood film is so thin as to exclude most of the corpuscles and is in sharp contrast with the remainder of the film. Light readily passes through the thin spot so that any movement thereof is easily seen. The instrument is now oscillated slowly relative to the horizontal plane and it will be observed that the thin spot in the film moves from side to side relative to the loop of wire 1. The oscillation is continued and it will be noted that the spot referred to continues to move long as the blood is uncoagulated. Just as soon as coagulation takes place, the thin spot becomes immobilized. This condition .of coagula'g tion occurs suddenly, thereby determining the end of the period of observation. As soon 'as the thin spot ceases to move when the in; strument is oscillated, the operator notes the time and thereby determines the length of; time of .the period from the moment ofobtaining a sample from the patent until coagulation has taken place. This determines the time factor of the patents blood coagulation, which is a very important fact in connection with preparation for a surgical operation.

' Figs. 3 and 4 illustrate a slight modification of the device in which the main bodyof the instrument is circular in form and the middle section 9 is provided with an opening I!) in which isset a washer or ring I l provided-with an opening. I'2. of proper size to support a film of blood. Back plate I4 is preferably translucent and of milk-White material while the top plate preferably is provided with a. tube IS in which is mounted a lens I"! through which the thin spot is'easily observed. V

W What I claim is z .1. An apparatus for determining the time period for the coagulation are specimen of-blood comprising, is main section provided with an opening, a film supporting. member having an aperture therein, theedges of which are capable of supporting a blood film bysurface tension and producing a thin spot in the film, saids'upporting member being carried by the main section within said openin said member being of less, thickness than said main section, a movable back section adapted to cover the. lower end of said opening, and a top section adapted to cover the upper end of said opening whereby said backv section and Saidtop section cooperate with the main sectiomto seal a blood film on saidfilm supporting'memb'er ag ainstievaporation.

2. An apparatus for determining. the. time period for the coagulation of 'a specimen of blood comprising, a supporting member having a small opening therein to support by surface tension the specimen of blood beingtested to produce a thin spot and with the axis ofsaid opening being normally substantially vertical, and sealing means to enclose said supporting member and to substantially seal said blood specimen on said supporting member from evaporation and with said specimen freely suspended within said supporting member, said sealing means having a portion thereof transparent whereby the opening in said supporting member is visible when said sealing means is effective.

3. An apparatus for determining the time period for the coagulation of a specimen of blood comprising, means to support a small film of blood by surface tension to produce a thin spot and with the edges of the film being in substantially a horizontal plane, and sealing means to prevent evaporation of said film of blood, said sealing means being out of contact with said film comprising, means to support afilm of blood by" surface tension to produce a thin spot and with the edges of the film being in a substantially horizontal plane, and sealing .means to enclose said means to prevent evaporation of said. film of blood, said sealing means being out of contact ing means above the film being transparent whereby the film may be viewed.

5. An apparatus for determining the time. period for the coagulation of a specimen of blood comprising, abody section provided with an opening, a blood film supporting member having an aperture therein and with the edges thereof capable. of supporting a blood filmi by. surface. tension and producing a thin spot in. the film, said supporting member being carried by. said body section and located within said opening, said member being of less thickness than the body section. and being spaced from the wall of said. opening in such manner as to prevent the blood film from contacting the upper and lower endS'of said opening in the body section a translucent back member adapted to'cover the lower end of said opening, and a top section through which said film may be viewed.

6. An apparatus for determining the time period for the coagulation of a specimen of blood comprising, a body section constituting a manually manipulable support, a blood fi-lmsupporting member having an aperture there-in with the edges thereof capable of supporting ablood film by surface tension and producing a. thin spot in the film, said supporting member being of less thickness than the body section with the aperture therein spaced from said-body section so as to prevent contact of the blood film with the body section.

ROBERT-L. ROWLAND.

US2312488A 1940-03-15 1940-03-15 Coagulometer Expired - Lifetime US2312488A (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2440472A (en) * 1944-09-11 1948-04-27 Belmont Radio Corp Stage incubator for microscopes
US2878715A (en) * 1956-02-06 1959-03-24 Mark C Rhees Method of blood plasma prothrombin time determinations
US3020748A (en) * 1959-05-18 1962-02-13 Bruce D Marshall Device for use in determining gel forming time of blood
US3029694A (en) * 1959-09-29 1962-04-17 Dantzic Morris Optical inspection accessory
EP0138190A2 (en) * 1983-10-15 1985-04-24 Klaus-Peter Dr. Völkl Apparatus for the in vitro measuring of coagulation time
US4568148A (en) * 1983-11-03 1986-02-04 Onanian Richard A Hand-held collapsible microscope system
US5191480A (en) * 1989-11-13 1993-03-02 Summagraphics Corporation Optical accessory for digitizer cursors
US6271920B1 (en) 1997-12-19 2001-08-07 Chromatics Color Sciences International, Inc. Methods and apparatus for color calibration and verification

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2440472A (en) * 1944-09-11 1948-04-27 Belmont Radio Corp Stage incubator for microscopes
US2878715A (en) * 1956-02-06 1959-03-24 Mark C Rhees Method of blood plasma prothrombin time determinations
US3020748A (en) * 1959-05-18 1962-02-13 Bruce D Marshall Device for use in determining gel forming time of blood
US3029694A (en) * 1959-09-29 1962-04-17 Dantzic Morris Optical inspection accessory
EP0138190A2 (en) * 1983-10-15 1985-04-24 Klaus-Peter Dr. Völkl Apparatus for the in vitro measuring of coagulation time
EP0138190A3 (en) * 1983-10-15 1987-04-22 Klaus-Peter Dr. Volkl Apparatus for the in vitro measuring of coagulation time
US4568148A (en) * 1983-11-03 1986-02-04 Onanian Richard A Hand-held collapsible microscope system
US5191480A (en) * 1989-11-13 1993-03-02 Summagraphics Corporation Optical accessory for digitizer cursors
US6271920B1 (en) 1997-12-19 2001-08-07 Chromatics Color Sciences International, Inc. Methods and apparatus for color calibration and verification

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