US20200008980A1 - Hybrid drape having a gel-coated perforated mesh - Google Patents

Hybrid drape having a gel-coated perforated mesh Download PDF

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US20200008980A1
US20200008980A1 US16/577,535 US201916577535A US2020008980A1 US 20200008980 A1 US20200008980 A1 US 20200008980A1 US 201916577535 A US201916577535 A US 201916577535A US 2020008980 A1 US2020008980 A1 US 2020008980A1
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mesh
fibers
adhesive
bonding
drape
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US16/577,535
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Christopher Brian Locke
Timothy Mark Robinson
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KCI Licensing Inc
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KCI Licensing Inc
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Priority to US201461945882P priority Critical
Priority to US14/619,714 priority patent/US10632020B2/en
Application filed by KCI Licensing Inc filed Critical KCI Licensing Inc
Priority to US16/577,535 priority patent/US20200008980A1/en
Assigned to KCI LICENSING, INC. reassignment KCI LICENSING, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LOCKE, CHRISTOPHER BRIAN, ROBINSON, TIMOTHY MARK
Publication of US20200008980A1 publication Critical patent/US20200008980A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0246Adhesive plasters or dressings characterised by the skin adhering layer
    • A61F13/025Adhesive plasters or dressings characterised by the skin adhering layer having a special distribution arrangement of the adhesive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/00051Accessories for dressings
    • A61F13/00068Accessories for dressings specially adapted for application or removal of fluid, e.g. irrigation or drainage of wounds, under-pressure wound-therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0203Adhesive plasters or dressings having a fluid handling member
    • A61F13/0216Adhesive plasters or dressings having a fluid handling member the fluid handling member being non absorbent, e.g. for use with sub- or over-pressure therapy, wound drainage or wound irrigation systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0246Adhesive plasters or dressings characterised by the skin adhering layer
    • A61F13/0253Adhesive plasters or dressings characterised by the skin adhering layer characterized by the adhesive material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0283Apparatus or processes for manufacturing adhesive dressings or bandages for making adhesive or cohesive tape or fabrics therefor, e.g. coating or mechanical treatments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/58Adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91Suction aspects of the dressing
    • A61M1/915Constructional details of the pressure distribution manifold
    • A61M1/0088
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91Suction aspects of the dressing
    • A61M1/912Connectors between dressing and drainage tube
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10Methods of surface bonding and/or assembly therefor
    • Y10T156/1052Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y10T156/1062Prior to assembly

Abstract

A system for treating a tissue site with negative-pressure is described. The system includes a manifold configured to be positioned adjacent to the tissue site and a drape configured to be positioned over the tissue site and the manifold to form a sealed space. The system also includes a negative-pressure source configured to provide negative-pressure to the sealed space. The drape includes a film layer, a layer of a bonding adhesive coupled to the film layer, and a mesh coupled to the layer of the bonding adhesive. The mesh includes a coating of a sealing adhesive and one or more bonding apertures. Methods of manufacturing the drape are also described.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • This application is a divisional of U.S. patent application Ser. No. 14/619,714, filed Feb. 11, 2015, entitled “HYBRID DRAPE HAVING A GEL-COATED PERFORATED MESH,” which claims priority to and the benefit of U.S. Provisional Patent Application No. 61/945,882, filed Feb. 28, 2014, entitled “HYBRID DRAPE HAVING A GEL-COATED PERFORATED MESH,” each of which is hereby incorporated by reference for all purposes.
  • FIELD
  • The present disclosure relates generally to dressings for adhering to a wound or tissue site, and more particularly, but without limitation, to a hybrid drape having a gel-coated perforated mesh.
  • BACKGROUND
  • Clinical studies and practice have shown that reducing pressure in proximity to a tissue site can augment and accelerate growth of new tissue at the tissue site. The applications of this phenomenon are numerous, but it has proven particularly advantageous for treating wounds. Regardless of the etiology of a wound, whether trauma, surgery, or another cause, proper care of the wound is important to the outcome. Treatment of wounds or other tissue with reduced pressure may be commonly referred to as “negative-pressure therapy,” but is also known by other names, including “negative pressure wound therapy,” “reduced-pressure therapy,” “vacuum therapy,” and “vacuum assisted closure,” for example. Negative-pressure therapy may provide a number of benefits, including migration of epithelial and subcutaneous tissues, improved blood flow, and micro-deformation of tissue at a wound site. Together, these benefits can increase development of granulation tissue and reduce healing times.
  • While the clinical benefits of negative-pressure therapy are widely known, the cost and complexity of negative-pressure therapy can be a limiting factor in its application, and the development and operation of negative-pressure systems, components, and processes continues to present significant challenges to manufacturers, healthcare providers, and patients.
  • SUMMARY
  • According to an illustrative, non-limiting embodiment, a dressing for treating a tissue site with negative pressure is described. The dressing may include a tissue interface configured to be positioned adjacent to the tissue site; and a sealing member configured to be positioned over the tissue interface and the tissue site to form a sealed environment. The sealing member may include a film layer, a layer of a bonding adhesive coupled to the film layer, and a mesh coupled to the layer of the bonding adhesive. The mesh may have a coating of a sealing adhesive and one or more bonding apertures.
  • According to another illustrative embodiment, a system for treating a tissue site with negative-pressure is described. The system may include a manifold configured to be positioned adjacent to the tissue site and a drape configured to be positioned over the tissue site and the manifold to form a sealed space. The system may also include a negative-pressure source configured to provide negative-pressure to the sealed space. The drape may include a film layer, a layer of a bonding adhesive coupled to the film layer, and a mesh coupled to the layer of the bonding adhesive. The mesh may have a coating of a sealing adhesive and one or more bonding apertures.
  • According to another illustrative embodiment, a method for manufacturing a drape for a negative-pressure system is described. A film layer may be provided, and a layer of a bonding adhesive may be coupled to the film layer. A mesh may be formed and coated with a sealing adhesive. One or more bonding apertures may be formed in the mesh, and the mesh may be coupled to the layer of the bonding adhesive.
  • Other aspects, features, and advantages of the illustrative embodiments will become apparent with reference to the drawings and detailed description that follow.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • Illustrative embodiments are described in detail below with reference to the attached drawings, which are incorporated by reference herein, and wherein:
  • FIG. 1 is a schematic diagram of an illustrative embodiment of a system for treating a tissue site with negative pressure;
  • FIG. 2 is an exploded perspective view of a drape that may be used with some embodiments of the systems of FIG. 1;
  • FIG. 3A is a plan view of a mesh that may be used with some embodiments of the drape of FIG. 2;
  • FIG. 3B is a perspective view of a portion of the mesh of FIG. 3A;
  • FIG. 3C is a side elevation view of a portion of the mesh of FIG. 3A;
  • FIG. 4 is a sectional view illustrating additional details that may be associated with some embodiments of the drape of FIG. 2 in a first state; and
  • FIG. 5 is a sectional view of the portion of the drape of FIG. 4 in a second state.
  • DETAILED DESCRIPTION
  • The following description of example embodiments provides information that enables a person skilled in the art to make and use the subject matter set forth in the appended claims, but may omit certain details already well-known in the art. The following detailed description is, therefore, to be taken as illustrative and not limiting.
  • The example embodiments may also be described herein with reference to spatial relationships between various elements or to the spatial orientation of various elements depicted in the attached drawings. In general, such relationships or orientation assume a frame of reference consistent with or relative to a patient in a position to receive treatment. However, as should be recognized by those skilled in the art, this frame of reference is merely a descriptive expedient rather than a strict prescription.
  • FIG. 1 is a sectional view of an example embodiment of a negative-pressure therapy system 100 illustrating details that may be associated with some embodiments for treating a tissue site 102 with negative pressure. As shown in the illustrative embodiment of FIG. 1, the negative-pressure therapy system 100 may include a dressing 104 fluidly coupled to a negative-pressure source 106. In some embodiments, the negative-pressure source 106 may be fluidly coupled to the dressing 104 by a conduit, such as a tube 112, and a connector, such as a connector 114. The dressing 104 may generally include a drape, such as a drape 108, and a tissue interface, such as a manifold 110. The drape 108 may have a film layer 124, a layer of a bonding adhesive 126, and a mesh 128. The drape 108 may be attached to an epidermis 116.
  • In general, components of the negative-pressure therapy system 100 may be coupled directly or indirectly to each other. For example, the negative-pressure source 106 may be directly coupled to the connector 114 and indirectly coupled to the manifold 110 through the connector 114. Components may be fluidly coupled to each other to provide a path for transferring fluids (such as, liquid, gas, or both liquid and gas) between the components.
  • In some embodiments, components may be fluidly coupled with a tube, such as the tube 112, for example. A “tube,” as used herein, broadly refers to a tube, pipe, hose, conduit, or other structure with one or more lumina adapted to convey fluids between two ends. Typically, a tube is an elongated, cylindrical structure with some flexibility, but the geometry and rigidity may vary. In some embodiments, components may additionally or alternatively be coupled by virtue of physical proximity, being integral to a single structure, or being formed from the same piece of material. Coupling may also include mechanical, thermal, electrical, or chemical coupling (such as a chemical bond) in some contexts.
  • In operation, a tissue interface, such as the manifold 110, may be placed within, over, on, against, or otherwise adjacent to a tissue site. For example, the manifold 110 may be placed against the tissue site 102, and the drape 108 may be placed over the manifold 110 and sealed to tissue proximate to the tissue site 102. Tissue proximate to a tissue site is often undamaged epidermis peripheral to the tissue site. Thus, the drape 108 can provide a sealed therapeutic environment 118 proximate to the tissue site 102. The sealed therapeutic environment 118 may be substantially isolated from the external environment, and the negative-pressure source 106 can reduce the pressure in the sealed therapeutic environment 118. Negative pressure applied uniformly through a tissue interface in the sealed therapeutic environment 118 can induce macrostrain and microstrain in the tissue site 102, as well as remove exudates and other fluids from the tissue site. The removed exudates and other fluids can be collected in a container and disposed of properly.
  • The fluid mechanics of using a negative-pressure source to reduce pressure in another component or location, such as within a sealed therapeutic environment 118, can be mathematically complex. However, the basic principles of fluid mechanics applicable to negative-pressure therapy are generally well-known to those skilled in the art, and the process of reducing pressure may be described illustratively herein as “delivering,” “distributing,” or “generating” negative pressure, for example.
  • In general, exudates and other fluids flow toward lower pressure along a fluid path. This orientation is generally presumed for purposes of describing various features and components of negative-pressure therapy systems herein. Thus, in the context of negative-pressure therapy, the term “downstream” typically implies something in a fluid path relatively closer to a negative-pressure source, and conversely, the term “upstream” implies something relatively further away from a negative-pressure source. Similarly, it may be convenient to describe certain features in terms of fluid “inlet” or “outlet” in such a frame of reference. However, a fluid path may also be reversed in some applications, such as by substituting a positive-pressure source, and this descriptive convention should not be construed as a limiting convention.
  • The term “tissue site” in this context broadly refers to a wound or defect located on or within tissue, including but not limited to, bone tissue, adipose tissue, muscle tissue, neural tissue, dermal tissue, vascular tissue, connective tissue, cartilage, tendons, or ligaments. A wound may include chronic, acute, traumatic, subacute, and dehisced wounds, partial-thickness burns, ulcers (such as diabetic, pressure, or venous insufficiency ulcers), flaps, and grafts, for example. The term “tissue site” may also refer to areas of tissue that are not necessarily wounded or defective, but are instead areas in which it may be desired to add or promote the growth of additional tissue. For example, negative pressure may be used in certain tissue areas to grow additional tissue that may be harvested and transplanted to another tissue location. In an illustrative embodiment, the tissue site 102 may be a wound that extends through the epidermis 116, through a dermis 120, and into subcutaneous tissue 122.
  • “Negative pressure” generally refers to a pressure less than a local ambient pressure, such as the ambient pressure in a local environment external to a sealed therapeutic environment 118 provided by the drape 108. In many cases, the local ambient pressure may also be the atmospheric pressure in a patient's vicinity. Alternatively, the pressure may be less than a hydrostatic pressure associated with tissue at the tissue site. Unless otherwise indicated, values of pressure stated herein are gauge pressures. Similarly, references to increases in negative pressure typically refer to a decrease in absolute pressure, while decreases in negative pressure typically refer to an increase in absolute pressure.
  • A negative-pressure source, such as the negative-pressure source 106, may be a reservoir of air at a negative pressure, or may be a manual or electrically-powered device that can reduce the pressure in a sealed volume, such as a vacuum pump, a suction pump, a wall-suction port available at many healthcare facilities, or a micro-pump, for example. A negative-pressure source may be housed within or used in conjunction with other components, such as sensors, processing units, alarm indicators, memory, databases, software, display devices, or operator interfaces that further facilitate negative-pressure therapy. While the amount and nature of negative pressure applied to a tissue site may vary according to therapeutic requirements, the pressure typically ranges between −5 millimeters of mercury (mm Hg) (−667 Pa) and −500 mm Hg (−66.7 kPa). Common therapeutic ranges are between −75 mm Hg (−9.9 kPa) and −300 mm Hg (−39.9 kPa).
  • A tissue interface, such as the manifold 110, can generally be adapted to contact a tissue site or other layers of a dressing. A tissue interface may be partially or fully in contact with a tissue site. If a tissue site is a wound, for example, a tissue interface may partially or completely fill the wound, or may be placed over the wound. A tissue interface may take many forms, and may be many sizes, shapes, or thicknesses depending on a variety of factors, such as the type of treatment being implemented or the nature and size of a tissue site. For example, the size and shape of a tissue interface may be adapted to the contours of deep and irregular shaped tissue sites.
  • In some embodiments, a tissue interface may be a manifold, such as the manifold 110. A “manifold” in this context generally includes any substance or structure providing a plurality of pathways adapted to collect or distribute fluid across a tissue site under negative pressure. For example, a manifold may be adapted to receive negative pressure from a source and distribute the negative pressure through multiple apertures across a tissue site, which may have the effect of collecting fluid from across a tissue site and drawing the fluid toward the source. In some embodiments, the fluid path may be reversed or a secondary fluid path may be provided to facilitate delivering fluid across a tissue site.
  • In some illustrative embodiments, the pathways of a manifold may be channels interconnected to improve distribution or collection of fluids across a tissue site. For example, cellular foam, open-cell foam, reticulated foam, porous tissue collections, and other porous material such as gauze or felted mat generally include pores, edges, and/or walls adapted to form interconnected fluid pathways. Liquids, gels, and other foams may also include or be cured to include apertures and flow channels. In some illustrative embodiments, a manifold may be a porous foam material having interconnected cells or pores adapted to uniformly (or quasi-uniformly) distribute negative pressure to a tissue site. The foam material may be either hydrophobic or hydrophilic. In one non-limiting example, a manifold may be an open-cell, reticulated polyurethane foam such as GranuFoam® dressing available from Kinetic Concepts, Inc. of San Antonio, Tex.
  • In some embodiments, such as embodiments in which the manifold 110 may be made from a hydrophilic material, the manifold 110 may also wick fluid away from a tissue site while continuing to distribute negative pressure to the tissue site. The wicking properties of the manifold 110 may draw fluid away from a tissue site by capillary flow or other wicking mechanisms. An example of a hydrophilic foam is a polyvinyl alcohol, open-cell foam such as V.A.C. WhiteFoam® dressing available from Kinetic Concepts, Inc. of San Antonio, Tex. Other hydrophilic foams may include those made from polyether. Other foams that may exhibit hydrophilic characteristics include hydrophobic foams that have been treated or coated to provide hydrophilicity.
  • A tissue interface may further promote granulation at a tissue site if pressure within the sealed therapeutic environment 118 is reduced. For example, any or all of the surfaces of the manifold 110 may have an uneven, coarse, or jagged profile that can induce microstrains and stresses at a tissue site if negative pressure is applied through the manifold 110.
  • In some example embodiments, a tissue interface may be constructed from bioresorbable materials. Suitable bioresorbable materials may include, without limitation, a polymeric blend of polylactic acid (PLA) and polyglycolic acid (PGA). The polymeric blend may also include without limitation polycarbonates, polyfumarates, and capralactones. The tissue interface may further serve as a scaffold for new cell-growth, or a scaffold material may be used in conjunction with the tissue interface to promote cell-growth. In general, a scaffold material may be a biocompatible or biodegradable substance or structure used to enhance or promote the growth of cells or formation of tissue, such as a three-dimensional porous structure that provides a template for cell growth. Illustrative examples of scaffold materials include calcium phosphate, collagen, PLA/PGA, coral hydroxy apatites, carbonates, or processed allograft materials.
  • In some embodiments, the drape 108 may provide a bacterial barrier and protection from physical trauma. The drape 108 may also be constructed from a material that can reduce evaporative losses and provide a fluid seal between two components or two environments, such as between a therapeutic environment and a local external environment. The drape 108 may be, for example, an elastomeric film or membrane that can provide a seal adequate to maintain a negative pressure at a tissue site for a given negative-pressure source. In some example embodiments, the drape 108 may be a polymer drape, such as a polyurethane film, that is permeable to water vapor but impermeable to liquid. Such drapes typically have a thickness in the range of about 25 microns to about 50 microns. For permeable materials, the permeability generally should be low enough that a desired negative pressure may be maintained.
  • An attachment device may be used to attach the drape 108 to an attachment surface, such as undamaged epidermis, a gasket, or another cover. The attachment device may take many forms. For example, an attachment device may be a medically-acceptable, pressure-sensitive adhesive that extends about a periphery, a portion, or an entire sealing member. In some embodiments, for example, some or all of the drape 108 may be coated with an acrylic adhesive having a coating weight between about 25 grams per square meter (gsm) to about 65 gsm. Thicker adhesives, or combinations of adhesives, may be applied in some embodiments to improve the seal and reduce leaks. Other example embodiments of an attachment device may include a double-sided tape, paste, hydrocolloid, hydrogel, silicone gel, or organogel.
  • A “container” broadly includes a canister, pouch, bottle, vial, or other fluid collection apparatus. A container, for example, can be used to manage exudates and other fluids withdrawn from a tissue site. In many environments, a rigid container may be preferred or required for collecting, storing, and disposing of fluids. In other environments, fluids may be properly disposed of without rigid container storage, and a re-usable container could reduce waste and costs associated with negative-pressure therapy. In some embodiments, a container may be a component of a negative-pressure source, such as the negative-pressure source 106.
  • A “connector,” such as the connector 114, may be used to fluidly couple a tube to a sealed therapeutic environment. The negative pressure developed by a negative-pressure source may be delivered through a tube to a connector. In one illustrative embodiment, a connector may be a T.R.A.C.® Pad or Sensa T.R.A.C.® Pad available from Kinetic Concepts, Inc. of San Antonio, Tex. In one exemplary embodiment, the connector 114 may allow the negative pressure generated by the negative-pressure source 106 to be delivered to the sealed therapeutic environment 118. In other exemplary embodiments, a connector may also be a tube inserted through a drape.
  • Negative-pressure therapy is increasingly being performed with smaller devices that use battery power rather than a connection to an electrical outlet. Use of battery power decreases the total power supply available to a device. As a result, power drains that would be considered negligible in a device powered through an electrical outlet connection may significantly reduce the performance of a battery-powered device. Power drains may be caused by low-level dressing leaks, for example, which can drain power by repeatedly triggering operation of the a negative-pressure source to maintain a therapeutic negative pressure at the tissue site. Power drains can shorten the useful life of a device by draining the device battery faster, requiring more frequent disposal of the device, recharging of the battery, or battery replacement. Leak detection techniques may help to identify some leaks that may be sealed by the user; however, low-level leaks can challenge the most sensitive leak detection systems and may often go undetected.
  • Low-level dressing leaks may occur between a drape and epidermis surrounding a tissue site if the drape fails to completely seal to the epidermis. Generally, a drape suitable for covering a tissue site for negative-pressure therapy may comprise a film having a thickness between about 25 microns and about 50 microns that is water-vapor permeable and formed of a polymer. The film, often formed of polyurethane, may be coated with an adhesive having a coating weight between about 25 gsm and about 65 gsm. The adhesive may often be acrylic-based and pressure sensitive. A standard acrylic adhesive may have a bond strength between about 1.8 Newton/centimeter (N/cm) and about 3.8 N/cm on stainless steel substrate at 23° C. at 50% relative humidity based on the American Society for Testing and Materials (“ASTM”) standard ASTM D3330. A pressure-sensitive adhesive increases in bond strength when pressed against the surface to which the adhesive is being bonded. In some applications, a pressure-sensitive adhesive may undergo a physical change when compressed against a surface. In other applications, a pressure-sensitive adhesive may flow into crevices of a surface when compressed, increasing the bond strength without undergoing a physical change. A drape using a standard acrylic adhesive as described above is generally suitable for a dressing where a negative-pressure source powered by a continuous power supply is available to compensate for a dressing leak.
  • Some drapes may use a bonding adhesive instead of the standard acrylic adhesive. A bonding adhesive may be an adhesive having a bond strength that is greater than the bond strength of a standard acrylic adhesive. In some embodiments, a bonding adhesive may be a type of acrylic adhesive. A bonding adhesive may be better for sealing, but the increased bond strength may cause significantly more discomfort if the drape is removed. In addition, removing a drape having a bonding adhesive may cause significant damage to delicate or damaged skin.
  • A drape that has a sealing adhesive can fill gaps between the drape and the epidermis to limit leaks and can be easy to remove with low discomfort to the patient. Generally, a sealing adhesive may have a lower bond strength than a standard acrylic adhesive and a bonding adhesive. Generally, a sealing adhesive may flow into gaps and crevices more readily than a standard acrylic adhesive or a bonding adhesive. Various sealing, gap-filling adhesives, such as silicone, hydrocolloids, and hydrogels, have been used but each can have drawbacks. For example, hydrogel adhesives are usually low tack and prone to swelling, creep, and mobility when used with fluid systems. Available hydrogels and hydrocolloids may not adhere well and may move when anchored. In another example, silicone adhesives can fill gaps and seal, but are not breathable and may lose mechanical bonding strength as the silicone adhesives interact with moisture during use. To counter these problems, silicone adhesives may require additional materials to secure the silicone adhesive to a patient. For example, a low-leak drape may be formed from two adhesive layers: a thick sealing adhesive, perhaps in the shape of a gasket or ring, and a thinner bonding adhesive layer used to keep the sealing adhesive in place. Low-leak drapes constructed in this way can be more complex than a drape using a single adhesive, increasing the complexity of manipulation and operation.
  • A hybrid drape having a thick sealing layer that is perforated and laminated over an adhesive-coated film can overcome many of these challenges. For example, a hybrid drape may include a film layer having a bonding adhesive applied directly to the film layer, and a sealing adhesive applied directly to the bonding adhesive. The sealing adhesive can be perforated to expose the bonding adhesive. When the drape is applied to a patient, the bonding adhesive can be pushed through the perforations of the sealing adhesive to secure the sealing adhesive to the patient. This laminated configuration may provide the benefits of the sealing adhesive and the bonding adhesive over the entire drape area. For example, the laminated configuration may be conformable and of sufficient strength to ensure an initial seal, can inhibit the development of typical low-level leaks, and can mechanically affix to an epidermis without secondary processes. The laminated configuration may also minimize application care by a user and can be removable with minimal trauma to a patient.
  • However, construction of a laminated configuration can require additional assembly steps and can increase an amount of materials that may be needed for drape construction, which can also significantly increase costs. In addition, as two layers of adhesive are applied to the film layer, the total thickness of the drape can significantly increase, reducing breathability of the drape. Still further, as two full layers of adhesive are applied, significantly more adhesive material is needed to construct the drape.
  • Other hybrid drapes may register a bonding adhesive and a sealing adhesive. These hybrid drapes apply both a bonding adhesive and a sealing adhesive directly to a film layer. The bonding adhesive and the sealing adhesive may each cover different portions of a film layer to reduce the overall thickness of a hybrid drape and decrease the amount of adhesive needed to construct the hybrid drape. However, the complexity of the manufacturing process may also increase costs relative to other drapes. While using less adhesive than the laminated hybrid drapes, registered hybrid drapes may still use more adhesive in construction than standard drapes.
  • Some hybrid drapes may use a gel coated mesh having mesh apertures with a diameter between about 5 millimeters (mm) and about 15 mm. However, a gel-coated mesh having apertures of this size may be unable to form a seal with a tissue site. The sealing properties of the gel-coated mesh may be improved by increasing an average diameter of the fibers used to form the mesh; however, the increased diameter of the fibers may also increase a prominence of a mesh where two fibers intersect. A prominence may be a relative height of a feature compared to surrounding features. If two fibers intersect so that a first fiber overlaps a second fiber, a prominence may be a distance between a top of a first fiber and the top of the second fiber. Generally, the prominence at an intersection of two fibers may be the diameter of the largest of the two intersecting fibers. Consequently, if the diameters of the fibers are increased to increase the sealing properties of a gel-coated mesh, the raised contours associated with fiber cross-over may create leaks that are difficult to seal.
  • As disclosed herein, the negative-pressure therapy system 100 can overcome these challenges and others by providing a substantially flat mesh coated with a sealing adhesive. In some embodiments, for example, the drape 108 may comprise a layer of a bonding adhesive coupled to a film layer, and a mesh layer coupled to the layer of bonding adhesive. The mesh layer may be a mesh formed of small diameter fibers and can be perforated to form bonding apertures. The mesh may be coated with a sealing adhesive.
  • FIG. 2 is an exploded perspective view, illustrating details that may be associated with some embodiments of the drape 108. The film layer 124 may be liquid-impermeable and vapor-permeable, allowing vapor to egress and inhibiting liquid from exiting. The film layer 124 may be a flexible film that is breathable and may have a high moisture-vapor transfer rate (MVTR). For example, in some embodiments, the MVTR may be greater than or equal to about 300 g/m2/24 hours. The film layer 124 may be formed from a range of medically approved films that typically range in thickness from about 15 microns (μm) to about 50 microns (μm). In other embodiments, a drape having a low MVTR or that allows no vapor transfer may be used. The film layer 124 can also function as a barrier to liquids and microorganisms.
  • The film layer 124 may be formed from numerous materials, such as one or more of the following: hydrophilic polyurethane (PU), cellulosics, hydrophilic polyamides, polyvinyl alcohol, polyvinyl pyrrolidone, hydrophilic acrylics, hydrophilic silicone elastomers, and copolymers of these. In an illustrative embodiment, the film layer 124 may be formed from a breathable cast matt polyurethane film sold by Expopack Advanced Coatings of Wrexham, United Kingdom, under the name INSPIRE 2301. The illustrative film may have an MVTR (inverted cup technique) of 14400 g/m2/24 hours and may be approximately 30 microns thick.
  • The bonding adhesive 126 may be coupled directly to the film layer 124. The bonding adhesive 126 may be a medically-acceptable, pressure-sensitive adhesive. For example, the bonding adhesive 126 may be formed from an acrylic adhesive, rubber adhesive, high-tack silicone adhesive, polyurethane, or other substance. In some illustrative embodiments, the bonding adhesive 126 may be formed from an acrylic adhesive with a coating weight of about 15 gsm to about 70 gsm. The bonding adhesive 126 may also be a high-bond strength acrylic adhesive, patterrubber adhesive, high-tack silicone adhesive, or polyurethane, for example. In some embodiments, the bonding adhesive 126 may have a peel adhesion or resistance to being peeled from a stainless steel material between about 6N/25 mm to about 10N/25 mm on stainless steel substrate at 23° C. at 50% relative humidity based on the ASTM D3330.
  • The bonding adhesive 126 may be a continuous layer of material or may be a layer with apertures (not shown). The apertures may be formed after application of the bonding adhesive 126 or may be formed by coating the bonding adhesive 126 in patterns on a carrier layer. The apertures may be sized to help control the resultant tackiness of the bonding adhesive 126. The apertures may also be sized to enhance the MVTR of the drape 108. The bonding adhesive 126 may couple the film layer 124 to the mesh 128.
  • In some embodiments, the mesh 128 may be a polymeric mesh, such as Mepitel® produced by Molnlycke Health Care, Adaptic® produced by Systagenix, and Noveface produced by Zodiac Aerospace Group. In some embodiments, the mesh 128 may be substantially flat. For example, the mesh 128 may have a thickness 129, and individual portions of the mesh 128 may have a minimal tolerance from the thickness 129. In some embodiments, the thickness 129 of the mesh 128 may be about 1 mm, and the tolerance of the thickness 129 may be less than about 2 mm. In another exemplary embodiment, a tolerance of the thickness 129 of the mesh 128 may be less than about 1 mm. In other embodiments, a tolerance of the thickness 129 of the mesh 128 may be less than about 0.5 mm. In some embodiments, the mesh 128 may be formed with bonding apertures 134. The bonding apertures 134 may be numerous shapes, for example, circles, squares, stars, ovals, polygons, slits, complex curves, rectilinear shapes, triangles, or other shapes.
  • FIG. 3A is a plan view, illustrating details that may be associate with some embodiments of the mesh 128. Generally, a mesh may include a structure of connected strands of metal, fiber, or other flexible or ductile material having openings between the strands. In some embodiments, a mesh may have evenly spaced openings between adjacent strands. In some embodiments, the mesh 128 may have a plurality of fibers 136. In some embodiments, the fibers 136 may be formed from a monofilament, a plurality of twisted monofilaments, a plurality of filaments, or a plurality of staple fibers. A filament may be a fiber that is formed in a continuous or near-continuous length. A monofilament may be a single filament. In some embodiments, a monofilament may be made from a single synthetic fiber of plastic, for example. Monofilaments may have a tensile strength related to a diameter of the monofilament and the type of material from which the monofilament is formed. A staple fiber may be a fiber of a selected standardized length, and the staple fiber may be formed of a suitable composition for used with a medical device. Each of the fibers 136 may have a diameter 127. In some embodiments, the diameter 127 may be no greater than about 1 mm. The fibers 136 may be formed from a range of materials including, but not limited to, silicone, cellulose acetate, and other similar materials.
  • In some embodiments, antimicrobial agents may be added to the mesh 128. In other embodiments, the fibers 136 may have antimicrobial properties. For example, in some embodiments, silver ions may be added to the fibers 136. In still other embodiments, the fibers 136 may be formed from elastomers to permit easier coverage of complex contours.
  • The plurality of fibers 136 may be woven, knitted, knotted, linked or otherwise connected to form a regular pattern of mesh apertures. In some embodiments, each of the plurality of fibers 136 may be separated from adjacent fibers 136 to form mesh apertures 139. In some embodiments, the fibers 136 may be separated a distance 138 from adjacent fibers, which may be between about 0.5 mm and about 4 mm. In some embodiments, each of the fibers 136 may be separated from adjacent fibers in a second direction by a distance 140. In some embodiments, the distance 140 may be between about 0.5 mm and about 4 mm. In some embodiments, the first direction of the distance 138 and the second direction of the distance 140 may be perpendicular. In some embodiments, the distance 138 and the distance 140 may be the same. In other embodiments, the first direction of the distance 138 and the second direction of the distance 140 may be other angles, and the distance 138 and the distance 140 may not be the same.
  • In some embodiments, the mesh apertures 139 may have an average effective diameter of about 1 mm. An effective diameter of a non-circular area may be a diameter of a circular area having the same surface area as the non-circular area. For example, the surface area of a mesh aperture 139 where the distance 138 is 0.5 mm and the distance 140 is 0.5 mm may be 0.25 mm2. The diameter of a circular area having a 0.25 mm2 surface area is about 0.56 mm; consequently, the effective diameter of the exemplary mesh aperture 139 is about 0.56 mm. Similarly, if the distance 138 is about 4 mm and the distance 140 is about 4 mm, the effective diameter of the mesh aperture 139 may be about 4.51 mm.
  • In some embodiments, the mesh 128 may include the bonding apertures 134. The bonding apertures 134 may have a uniform pattern or may be randomly distributed on the mesh 128. The bonding apertures 134 may be formed through one or more fibers 136. In some embodiments, the bonding apertures 134 may extend into the mesh apertures 139. Each bonding aperture 134 of the plurality of bonding apertures 134 may have an effective diameter. The average effective diameter of each bonding aperture 134 may be in the range of about 5 mm to about 15 mm.
  • In some embodiments, the mesh 128 may be coated with a gel, such as a sealing adhesive 144. In some embodiments, the sealing adhesive 144 may have a coating weight of about 100 gsm to about 500 gsm. In other embodiments, the sealing adhesive 144 may have a coating weight greater than about 200 gsm. The coating of the mesh 128 with the sealing adhesive 144 may fill in a portion of each mesh aperture 139. In some embodiments, the mesh apertures 139 may remain at least partially open after the coating of the mesh 128 with the sealing adhesive 144.
  • A sealing adhesive may be a soft material that provides a good seal with the tissue site 102. A sealing adhesive may be formed of a silicone gel (or soft silicone), hydrocolloid, hydrogel, polyurethane gel, polyolefin gel, hydrogenated styrenic copolymer gels, or foamed gels with compositions as listed, or soft closed cell foams (polyurethanes, polyolefins) coated with an adhesive (for example, 30 gsm-70 gsm acrylic), polyurethane, polyolefin, or hydrogenated styrenic copolymers. In some embodiments, a sealing adhesive may have a stiffness between about 5 Shore OO and about 80 Shore OO. A sealing adhesive may be hydrophobic or hydrophilic. A sealing adhesive may be an adhesive having a low to medium tackiness, for example, a silicone polymer, polyurethane, or an additional acrylic adhesive. In some embodiments, a sealing adhesive may a bond strength between about 0.5N/25 mm and about 1.5N/25 mm on a stainless steel substrate at 23° C. at 50% relative humidity based on ASTM D3330. A sealing adhesive may have a tackiness such that the sealing adhesive may achieve the bond strength above after a contact time of less than 60 seconds. Tackiness may be considered a bond strength of an adhesive after a very low contact time between the adhesive and a substrate. In an illustrative embodiment, a sealing adhesive may have a tackiness that may be about 30% to about 50% of the tackiness of a bonding adhesive.
  • In some embodiments, the bonding apertures 134 may be formed prior to coating of the mesh 128 with the sealing adhesive 144. In other embodiments, the bonding apertures 134 may be formed in the mesh 128 following coating of the mesh 128 with the sealing adhesive 144.
  • In some embodiments, the fibers 136 of the mesh 128 may form a plurality of intersections 142. In some embodiments, an intersection 142 may be a location of the mesh 128 where at least two fibers 136 overlap, cross-over, or meet, for example.
  • FIG. 3B is a perspective view, illustrating additional details that may be associated with some embodiments of the mesh 128 of FIG. 3A. In some embodiments, the mesh 128 may be formed so that at each intersection 142, the intersecting fibers 136 may be fused so that the intersection 142 is planar. In some embodiments, the mesh 128 may be molded, extruded, or expanded to form the mesh 128. In embodiments where the mesh 128 is molded, extruded, or expanded, the fibers 136 at an intersection 142 may be fused or joined so that a prominence at the intersection 142 is less than about 1 mm. In some embodiments, the prominence at an intersection 142 may be about 0 mm. In some embodiments, a substantially flat mesh may have a thickness at the intersections 142 that may be substantially the same as a thickness of the mesh 128 surrounding the intersections 142.
  • FIG. 3C is a side elevation view, illustrating additional details that may be associated with some embodiments of the mesh 128. In some embodiments, the mesh 128 may be formed by weaving or knitting the fibers 136. If the fibers 136 are woven or knitted, the intersections 142 may have a prominence 141. In some embodiments, the prominence 141 of the fibers 136 at the intersections 142 may be equal to the diameter 127 of the fibers 136. In some embodiments, the prominence 141 may be reduced by compressing the mesh 128 following weaving or knitting the fibers 136. The prominences 141 of the fibers 136 may also be reduced by passing the mesh 128 through a calender, which may apply pressure to the mesh 128 to smooth out the mesh 128. In some embodiments, the prominence 141 may be less than about 1 mm.
  • FIG. 4 is a sectional view, illustrating additional details that may be associated with some embodiments of the drape 108. In the assembled state, the bonding adhesive 126 may be coupled to the film layer 124, and the mesh 128 may be coupled to the bonding adhesive 126. If the mesh 128 is placed proximate to or in contact with the epidermis 116, the sealing adhesive 144 coating the mesh 128 may form sealing couplings 146 with the epidermis 116. In some embodiments, the diameter 127 of the fibers 136, the thickness of the sealing adhesive 144, and the bonding apertures 134 may create a gap between the bonding adhesive 126 and the epidermis 116.
  • FIG. 5 is a sectional view, illustrating additional details that may be associated with some embodiments of the drape 108 of FIG. 4 in a second position. If the drape 108 is in a desired location, pressure may be applied to the film layer 124. The pressure may cause the bonding adhesive 126 to be pressed at least partially into contact with the epidermis 116 to form bonding couplings 150. The bonding couplings 150 may provide secure, releasable mechanical fixation to the epidermis 116. The sealing couplings 146 between the sealing adhesive 144 and the epidermis 116 may be sufficient to seal the film layer 124 to the epidermis 116. The sealing couplings 146 may not be as mechanically strong as the bonding couplings 150 between the bonding adhesive 126 and the epidermis 116. The bonding couplings 150 may also anchor the drape 108 to the epidermis 116, inhibiting migration of the drape 108 and the sealing adhesive 144.
  • The average effective diameter of the bonding apertures 134 of the sealing adhesive 144 may be varied as one control of the tackiness or adhesion strength of the drape 108. In this regard, there may be an interplay between three main variables for each embodiment: the diameter 127 of the fibers 136, the average effective diameter of the plurality of bonding apertures 134, and the tackiness of the bonding adhesive 126. The more bonding adhesive 126 that extends through the bonding apertures 134, the stronger the bonding coupling 150. The smaller the diameter 127 of the fibers 136, the more the bonding adhesive 126 generally extends through the bonding apertures 134 and the greater the bonding coupling 150. As an example of the interplay, if a very tacky bonding adhesive 126 is used and the diameter 127 of the fibers 136 of the mesh 128 is small, the average effective diameter of the plurality of bonding apertures 134 may be relatively smaller to maintain a same adhesion strength of the drape 108.
  • In other embodiments, the mesh 128 may be formed from a perforated film which is then coated with the sealing adhesive 144 and laminated to the film layer 124 or the bonding adhesive 126. In other embodiments, the mesh 128 may be coated with the bonding adhesive 126 and then pattern-coated with the sealing adhesive 144. The mesh 128 may then be laminated directly to the film layer 124. The bonding adhesive 126 may be exposed through the areas of the mesh 128 that were not pattern-coated with the sealing adhesive 144.
  • In some embodiments, the adhesives may be mixed with blowing or expanding agents, for example organic and inorganic low temperature boiling point liquids. The blowing or expanding agents allow for the adhesives to expand under the application of heat or light to increase the thickness of the adhesive following deposition by one of the above described processes. The blowing or expanding agents may reduce the amount of adhesive needed and decrease the cost of production. In some embodiments, the application of heat or light may be delayed until application of the drape 108 to the epidermis 116 so that the contact area with the epidermis 116 may increase as the bonding adhesive 126 and the sealing adhesive 144 warm by contact with the epidermis 116. The application of light or heat following application of the drape 108 to the epidermis 116 can provide a better seal for some embodiments of the drape 108 to the epidermis 116.
  • A drape having a coated mesh may provide a lower cost solution that makes more efficient use of a sealing adhesive. The increase in efficiency of the use of a sealing adhesive may be accomplished without the complication of adding extruders and pattern coaters that may be required for pattern printing of adhesives. A drape having a coated mesh may have a higher MVTR than other drapes as the inclusion of mesh apertures can permit greater passage of moisture without interfering with sealing.
  • Although certain features and their advantages have been disclosed in the context of certain illustrative, non-limiting embodiments, it should be understood that various changes, substitutions, permutations, and alterations can be made without departing from the scope of the appended claims. It will be appreciated that features that may be described in connection to one embodiment may also be applicable to other embodiments. It will also be understood that the benefits and advantages described above may relate to one embodiment or may relate to several embodiments. It will further be understood that reference to “an” item refers to one or more of those items.
  • The steps of the methods described herein may be carried out in a suitable order, or simultaneously where appropriate.
  • Where appropriate, aspects of the embodiments described above may be combined with aspects of the other embodiments described to form further examples having comparable or different properties and addressing the same or different problems.
  • It will be understood that the embodiments described herein are given by way of example only and that various modifications may be made by those skilled in the art. The above specification, examples and data provide a complete description of the structure and use of exemplary embodiments. Although various embodiments have been described above with a certain degree of particularity, or with reference to one or more individual illustrations, those skilled in the art could make numerous alterations to the example embodiments without departing from the scope of the claims.

Claims (17)

1.-34. (canceled)
35. A method for manufacturing a drape for a negative-pressure system, the method comprising:
providing a film layer;
coupling a layer of a bonding adhesive to the film layer;
forming a mesh;
coating the mesh with a sealing adhesive;
forming one or more bonding apertures in the mesh; and
coupling the mesh to the layer of the bonding adhesive.
36. The method of claim 35, wherein the bonding apertures are formed in the mesh before coating the mesh.
37. The method of claim 35, wherein forming the mesh comprises weaving a plurality of fibers to form the mesh.
38. The method of claim 35, wherein forming the mesh comprises knitting a plurality of fibers to form the mesh.
39. The method of claim 35, wherein forming the mesh comprises extruding a plurality of fibers to form the mesh.
40. The method of claim 39, wherein extruding the plurality of fibers to form the mesh further comprises extruding the fibers so that the fibers intersect with a prominence less than about 1 millimeter.
41. The method of claim 35, wherein the mesh comprises a plurality of fibers and a diameter of each fiber is less than about 1 millimeter.
42. The method of claim 35, wherein the mesh comprises a plurality of fibers and each fiber comprises a monofilament.
43. The method of claim 35, wherein the mesh comprises a plurality of fibers and each fiber comprises a plurality of twisted monofilaments.
44. The method of claim 35, wherein the mesh comprises a plurality of fibers and each fiber comprises a staple fiber.
45. The method of claim 35, wherein forming the mesh comprises forming the mesh from a plurality of fibers having intersections and compressing the mesh to reduce a prominence at each intersection of the fibers.
46. The method of claim 35, wherein forming the mesh comprises forming the mesh from a plurality of fibers having intersections and calendaring the mesh to reduce a prominence at each intersection of the fibers.
47. The method of claim 35, wherein forming the mesh comprises forming the mesh to have a plurality of mesh apertures each having an effective diameter between about 0.5 millimeters and about 4 millimeters.
48. The method of claim 35, wherein coating the mesh comprises applying a coating weight of the sealing adhesive between about 100 grams per square meter and about 500 grams per square meter.
49. The method of claim 35, wherein forming the bonding apertures in the mesh comprises forming each bonding aperture with an effective diameter between about 5 millimeters and about 15 millimeters.
50. (canceled)
US16/577,535 2014-02-28 2019-09-20 Hybrid drape having a gel-coated perforated mesh Pending US20200008980A1 (en)

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EP3110379A1 (en) 2017-01-04
WO2015130471A1 (en) 2015-09-03
CA2940730C (en) 2022-07-26
EP3479803A1 (en) 2019-05-08
EP3479803B1 (en) 2021-03-31
US20150245949A1 (en) 2015-09-03
EP3110379B1 (en) 2019-04-03
EP3848009A1 (en) 2021-07-14
US10632020B2 (en) 2020-04-28

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